Daily Archives: March 21, 2017

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Western medicine and alternative healing are kind of like leggings and leather jacketsat one point itwas rare to see them pairedtogether,butnow theyre considered to bea pretty perfect match.

For proof, just take a stroll through any major US hospital. Therapies such as acupuncture, meditation, and yoga, which were unheard of many years ago, are now commonly offered to patients while receiving cardiac, oncology, and fertility treatments, to name but a few, says Nada Milosavljevic, MD, a board-certified physician, faculty member at Harvard Medical School, and founder of Sage Tonic,which createswellness tool boxes for common medical maladies.

So how do you know whether your headaches merit an herbal tincture or an Rx for Imatrex? The short answer: Its really complicated.

That said, not all alt-therapies have attained BFF status with their conventional counterparts. (You wont find many shamanic healing ceremonies going down in the ICU.) Plus, theres still some debate in the medical community around when its appropriate to seek out alternative treatments and when traditional interventions are best.

So how do you know whether your headaches merit an herbal tincture or an Rx for Imatrex?

The short answer: Its really complicated. But while every practitioner has her own opinion on the topic, there are some guidelines that all docs and holistic healers can agree upon.

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On the more traditionaltip, some doctors insist that if youre seeking out a complementary therapy, its crucial to consult with themeven if its something as seemingly harmless as yogato quell anxiety.

Its important to have an evaluation and discuss treatment options with a health care provider to make sure you receive the best care possible, says Wendy Weber, ND, PhD, a branch chief of clinical research at the National Center for Complementary and Integrative Health. Once you have a clear diagnosis, then you can explore what treatments are best for you with your providers.

While many herbs are safe to use, theres always the potential for them to interact with medications the patient may currently take.

Other docs, however, say super-low-risk modalities usuallydont require their sign-off. For a mild condition like day-to-day stress, trying meditation or acupressure might be fine, says Dr. Milosavljevic.

One things for sure: If youre taking medication, you should definitely talk to your doctorbefore adding anything ingestible to your treatment regimen. Lets say a patient is on several medications and is interested in trying an herbal treatment, says Dr. Milosavljevic. While many herbs are safe to use, theres always the potential for them to interact with medications the patient may currently take.

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Some doctors wont wholeheartedly recommend a holistic therapy unless it has a librarys worth of evidence behind it for the specific condition in question. But that kind of heavyresearch isnt always readily available in the world of alt-health.

For example, the NCCIH claims research is too limited to proveacupuncture is avalidfix for anxiety, even though just about anyone in the Chinese medicine world would call foul on that logic. Meanwhile, the same organization has given acupuncture the thumbs-up for treating back pain, since extensive research has proven it works.

Holistic practitioners also take science into consideration, of coursebut their practices have often been tested and confirmed over centuries. For many, thats proof enough of their crafts legitimacy (even if mountains of data arent there).

Holistic practitioners also take science into consideration, of coursebut their practices have often been tested and confirmed over centuries.

Take that acupuncture example, for instance. From the perspective of Chinese medicine, acupuncture can help with everything, says Ro Giuliano, an acupuncturist and herbalist at Brooklyns Maha Rose Center for Healing Arts. But sometimes it would stand alone, and sometimes it would be in conjunction with Western medicine. (More on that in a minute.)

Either way, always do your homework to ensure the treatment youre curious about has been deemed safe for your condition. (Check out the NCCIH for all the deetsand, of course, ask your doctor.)

And once youve determined youre in the no-sketch zone, make certain your holistic pro is the real deal. Its important that you seek out trained, licensed, or certified providers of any complementary health approach that you decide to use, Weber stresses.

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Theres no debating this one: If youre seriously sick or injured, haul assto aWestern doctor.

Even holistic practitioners, like Ayurvedic naturopath Meghana Thanki, will co-sign this. We can do so much with Ayurveda, but I feel theres definitely a place for Western medicinemostly for emergencies and for some of their diagnostic tools, she says. Herbalists will also make thecase for pharmaceuticals in certain situations. Even though there are herbs with antimicrobial properties, there are a lot of times where you just need antibiotics, says Giuliano.

Even though there are herbs with antimicrobial properties, there are a lot of times where you just need antibiotics.

Thats not to say that alternative therapies cant buddy up with conventional treatmentslike getting reikiwhile receiving cancer treatmentbut again, its important to get your doctors blessing first. Some alternative therapies might not be possible for some conditions, due to their severity or complexity, points out Dr. Milosavljevic.

Bottom line:Its always best to err on the side of caution, so pursuescience-backed holistic treatments in conjunction with Western medicine, where appropriateand make sure your doctor stays in the loop.

The healthworld is full of hot debates: Is coffee really good for you? Are long or short workouts better? Big breakfast or a small one?

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When to seek out alternative medicineand when to go mainstream - Well+Good

Photo Courtesy of Manuel Aregullin

Manuel Aregullin, senior research associate, is an expert on plant pharmacology.

Cornell is a gold mine of fantastic gardens, beautiful foliage and abundant flora. In just the five-minute walk from Mann Library to Rockefeller Hall, one can see trees of all sizes and a wide variety of flowers. With colorful flower blossoms in spring and large full trees in summer, the valley, campus walkways and gardens are scenic masterpieces for much of the year. But there is much more to these shrubs, leaves or grasses than meets the eye.

Cancer, Alzheimers and Diabetes are all debilitating diseases. Their treatments routinely involve drugs containing a wide of variety of artificially synthesized chemicals. Is it possible that plants possess chemistry just as powerful as that in synthetically designed drugs? Could the plants we see as decorative be the sources of a new generation of drugs?

Natural remedies have been an important part of human history and extracting medicine from plants is not a new notion. However, investigating the properties of plants that may help provide better, more effective drugs or help us better understand disease biology is not as well established. As of late, the scientific community has fostered a unique interest in plant chemistry with booming trends in plant-based alternative medicines and all-natural remedies, either as initial treatment or as last resorts. According to Global Industry Analysts, the global herbal supplements and remedies market is expected to be valued at $115 billion by 2020. With rising health-care awareness among consumers, corporations will take a larger interest in producing products based on herbal and botanical extracts.

The Sun sat down with Senior Research Associate Manuel Aregullin, plant biology, to talk about the growing interest in alternative medicine and his laboratorys unique focus on plant pharmacology.

The medicinal use of plants remains a very important component of the healthcare system of many cultures around the globe and students are interested in learning about this topic. Cornell has made an effort in addressing that interest in the past through a diversity of courses in plant biology, Aregullin said.

The School of Integrated Plant Sciences offers a plants and human health concentration but does not have a dedicated major on the topic. Crop studies on functional foods or foods that provide benefits beyond nutrition, have been conducted at Cornell, but not many have focussed on plant based drugs.

No one was really working on the pharmacology of a particular plant, whether it was the chemical or biological aspect, for a specific purpose, for a practical motive or looking for something that could result in a new drug lead, Aregullin said. A number of courses, such as plant toxicology and pharmacology, that would fulfill the requirements of a major in plant and health sciences do not exist.

I lecture on botanical pharmacology in the courses I teach, but that is only relevant when you look at plants as medicinals, Aregullin said. The major will bring in a formal robust academic foundation to the importance of plants in human health. Aregullin and his colleagues expressed their excitement that many students interested in studying plant medicinals intend to attend medical school.

I think that to have some kind of background to the understanding of plants as medicinals is important in the medical practice for a number of reasons, Aregullin said. Some patients use plants as a form of complementary medicine while for others it is an alternative and it is always advantageous for the practitioner to acknowledge the natural origin of a prescription drug in clinical use.

Often, in medical school training, the number of courses on plant pharmacology are fairly limited and physicians have poor knowledge of what consequences certain alternative medicines may have. This gap needs to be urgently filled if physicians are to know how plant-based drugs react with conventional ones.

Rarely does botany address the medicinal chemistry of a plant, Aregullin said. A large segment of the population is consuming natural remedies as supplements and we need to know what is in them and if there is a benefit.

However, conducting research on plant chemistry and its possible therapeutic benefits is not easy.

The National Science Foundation will only help fund what they think will be the most effective drug, which will not necessarily come from a plant. Research in clinical areas gets much more funding; there is little funding going towards ventures which are not pivotal to the pharmaceutical industry, Aregullin said. It is a little bit complicated.

However, Aregullins research continues. A crucial point of focus is drug discovery based on disease biology and plant chemistry. Aregullin explains that the first step is to establish the hierarchy of the study. The study usually begins with an investigation of either the treatments goals or a plants chemistry, with subsequent steps intended to find a connection between the two.

If the lab begins by looking at diseases and their treatments, they often begin by looking at developments in the pharmaceutical industry. Clinically validated modes of actions, the process of substance-initiated functional or anatomical changes at the cellular level, are then targeted. Understanding the underlying chemistry behind this mode of action is crucial so that one can identify such chemistry in certain plants.

One criterion by which plants are chosen for study is history. Because of the way certain plants have been used by different groups over the centuries, theories of their benefits have surfaced.

There is a historical background to most plants, if you give weight to that, chances are that the therapeutic health benefit is real, I concur with the idea that the persistent use of a plant for a specific medicinal purpose could reflect efficacy and safety, Aregullin said.

A particular group that Aregullins lab looks at closely is the Iroquois. The team is investigating the species they use in order to prevent the contribution of starch to higher blood sugar. Northeast American ethnobotany, the study of a regions plants, is very robust and diverse. Therefore, research does not require traveling vast distances to access plants. In fact, many of the plants used in the lab have been collected from Cornells grounds.

When there is a lack of ethnobotanical information, Aregullin looks at particular plant chemistries which have been found to be therapeutic, in a process he calls template chemistry. Once such chemicals have been properly identified, Aregullin can identify new plants that may be used to provide similar benefits. Aregullin is also working on what he calls combinatorial pharmacology, studies in which treatments for two types of diseases are found from similar plant chemistry because of the similarity between these diseases.

With a higher number of natural pharmaceuticals expected to hit the market in the coming years, there is a serious need for physicians to understand the chemical basis for these medicines. Furthermore, as pharmaceutical companies see manufacturing costs rise, studies like Aregullins could provide the foundation for a new generation of alternative, natural medicines.

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Roots, Shoots and a Dash of Medicine - Cornell University The Cornell Daily Sun