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Daily Archives: March 1, 2017
Meet the weaponized propaganda AI that knows you better than you know yourself – ExtremeTech
Posted: March 1, 2017 at 9:15 pm
Is it worse to be distracted by irrelevant ads, or to be monitored closely enough that the ads are accurate but creepy? Why choose? (Why not Zoidberg?) One company called Cambridge Analytica has managed to apply what some are calling a weaponized AI propaganda machine in order to visit both fates upon us at once. And its all made possible by Facebook.
Cambridge Analytica specializes in the mass manipulation of thought. One way they accomplish this is through social media, particularly by deploying native advertising. Otherwise known as sponsored content, these are ads designed to fool you into assimilating the ad unchallenged. The company also uses Facebook as a platform to push microtargeted posts to specific audiences, looking for the tipping point where someones political inclination can be changed, just a little bit, for the right price. Much like Facebook games designed specifically for their addictive potential, rather than for any entertainment value, these intellectual salesmen exist solely to hit every sub-perceptual lever in order to bypass our conscious barriers.
Cambridge Analytica is one subsidiary of a UK-based firm called SCL for Strategic Communication Laboratories that does business in psychometrics, an emerging field concerned with applying the big data approach to psychology and the social sciences. SCL also claims secretive but highly paid disinformation and psy-ops contract work on at least four continents. Their CV includes work done on the public dime here in America, training our military for counterterrorism. Also among their services is the euphemistically named practice of election management. They are riding to fame or at least better funding on the coattails of Donald Trumps ascension to the White House, for which they claim no small degree of responsibility.
If you want certainty, you need scale, their website asserts, and they say theyre just the outfit to provide it. Like any business proposition, this is best taken with some skepticism. But turning political tides in favor of the highest bidders ideology is their whole business model. Their parent company claims to have exerted material influence over elections and other geopolitical outcomes in 22 countries. They, and Cambridge Analytica as their agent, claim to be mindshare brokers of the highest order.
Image source: Cambridge Analytica
Nobody iswilling to go on the record and put their name to assertions that the emperor has no clothes, for fear of incurring the wrath of newly powerful Cambridge Analytica board member Steve Bannon, or yanking too hard on the Koch brothersmonetary speech apparatus. Its not clear whether Cambridge Analytica is pulling the strings they say theyre pulling, or just really good at knowing what side is going to win. But they definitely have something under their hats.
There are a few fundamental tech applications that underlie what Cambridge Analytica claims it can do. But they all depend on the idea that artificial intelligence isnt some dissimilar alien entity, sprung fully self-actualized from the forebrain of humanity like HAL. AI is an extension of human intelligence, which we accomplish by applying the organization and data-handling power of computers to our own tasks and problems. On a reductionist level, all theyre doing at Cambridge Analytica is using more RAM and a rigorous, written-down set of rules to organize and manipulate data that social scientists handled with clipboards and calculators and pencils back in the day. The AI that enables the entire business model is likely an intellectual descendant of Dr. Michal Kosinskis work in the Cambridge University social sciences department and an illegitimate one, if you ask Kosinski himself. The story reads like a film noir.
It starts with the marriage of Facebook, psychology, and AI. Facebook activity has an uncanny amount of predictive power. Back in the 80s, scientists developed the questionnaire-based OCEAN model of five major psychological traits, still in use today. Michal Kosinskis 2014 PhD project rested on a psychometric Facebook survey called MyPersonality, which added AI to the mix. MyPersonality catalogued participants Facebook profile information including social connections and Likes, and also asked the participants to take a Facebook quiz to find out their OCEAN scores. Then it used machine learning to predict their OCEAN scores based on their Facebook activity. With only a persons Facebook likes plugged into a MyPersonality dossier, Kosinskis AI could reliably predict their sexual orientation, ethnicity, religious and political views, personality traits, intelligence, happiness, use of addictive substances, parental separation, age, and gender.
Success rates for Kosinskis prediction algorithm. Source
More data meant a better guess, of course. Seventy likes were enough to make the AIs prediction of a persons OCEAN score better than their friends could do, 150 made it more accurate than what their parents got, and 300 likes could do better predicting a persons OCEAN score than the best human judge of a person: their spouse. More likes could even surpass what a person thought they knew about themselves, by predicting their OCEAN score closer than the persons own best estimate of what their score would be.
It goes the other way, too. To a database, a persons name and entries from their profile are just nodes in an n-dimensional space, and the connections between nodes arent necessarily directional. You can class individuals by similarities in the data, or you can search the data for individuals who fit into a class. Its as simple as doing an alphabetical sort in an Excel sheet.
Working with the predictive power of Facebook likes and quizzes became Kosinskis stock in trade. Kosinski even used Amazons Mechanical Turk in some of his research, crowdsourcing his quizzes to probe what made people respond to them. (Spoiler: getting paid helps.) His work earned him a deputy directorship at Cambridges Psychometrics Centre. It also earned him the attention of SCL. Kosinski told Motherboard that in 2014, a junior professor in his department named Aleksandr Kogan cold approached him asking for access to the MyPersonality database. Kogan, it turns out, was affiliated with SCL. Kosinski Googled Kogan, discovered this affiliation and declined to collaborate. But his research and methods were already in the wild, which meant in Kogans hands.
Kogan founded his own company that contracted with SCL to do psychometrics and predictive analysis, using aggregated Facebook data and a governing AI. At least some of this data came from jobs posted to Mechanical Turk, where participants were paid about $1 in exchange for access to Facebook profile data. Kogan changed his name and moved to Singapore. Kosinski remained deputy director of the Psychometrics Centre until he moved to the States in 2014.
Facebook has been in the news again and again because of the sheer extent of their data collection. One way they get the information they have is by using a thing called a conversion pixel. You know that stupid social network widget thats on every web page these days, including this one? Its designed to let you like and share a page without having to navigate back to Facebook. It also affords incredible mass surveillance opportunities. Every time you visit a web page with a Facebook share widget, you query one of Facebooks servers for a conversion pixel. Facebook then promptly attempts to phone home with what link you visited, how long you lingered on the page, whether you scrolled down or signed up or bought anything, and whether you chose to Like or share the page, plus the text of whatever comment you might post at the bottom using your Facebook profile. Even if you delete the text and dont publish the post. Likes already have enough predictive power; between likes and activity, that widget can produce a comprehensive set of metadata on a persons personality.
When logged-in users take Facebook quizzes like Kosinskis, the quiz can ask for permission to scrape any or all of this data out of their Facebook profile and into the hands of any marketer, data analyst, or election management specialist willing to pay for it. Between that and purchasing life history data and credit reports from brokers like Experian, this is how Cambridge Analytica profiles their marks in the first place. In return maximum you get to post a little quizlet thing to your wall, so you and all of your friends data can know which Walking Dead character each of you would be.
This is not an exchange of equivalent value.
CORAL!
And then theres microtargeting: the idea that Alice the Advertiser can accurately change the mind of Bob the Buyerbased on information Alice can buy.
The notion of microtargeting is not itself new, but what Cambridge Analytica is doing with it is novel. Theyre using the Facebook ecosystem because it perfectly enables the goal of targeting individuals and using their longer-lasting personality characteristics like a psychological GPS. It all hinges on a Facebook advertising tool called unpublished posts. Among advertisers, these are simply called dark posts.
Normally, when you make a Facebook post, it appears on your Timeline within your current privacy settings; this is true for people and Pages alike. When an advertiser makes a dark post, though, they can choose to serve that post to only a certain subset of users. Nobody sees it but the people the advertiser was targeting. And theyre canny about choosing their targets, looking for persuadable voters.
For example,explained Cambridge Analyticas CEO Alexander Nix in an op-ed last year about the companys work on the Ted Cruz presidential campaign, our issues model identified that there was a small pocket of voters in Iowa who felt strongly that citizens should be required by law to show photo ID at polling stations.
Almost certainly informed by Kosinskis work on Facebook profiling, Cambridge Analytica used the OCEAN model to advise the Cruz campaign on how to capture the vote on the issue of voter ID. The approach: use machine learning to classify, target, and serve dark posts to specific individuals based on their unique profiles, in order to use this relatively niche issue as a political pressure point to motivate them to go out and vote for Cruz. Later, Cambridge Analytica would use the same approach for the Trump campaign. Its not possible to make a complete count, but various places around the web have claimed that Cambridge Analytica tested between 45,000 and 175,000 different dark posts on the days of the Clinton-Trump debates.
Where do they get all the content to serve? Its difficult to say, because Cambridge Analytica doesnt respond to journalists who ask them about their methods. But the $6 million or so Trump has paid Cambridge Analytica can only pay just so many people for just so long. One journalist has been digging into this issue, and his research strongly suggests that much of the political propaganda surrounding the 2016 election was procedurally generated using machine learning, and then packaged and served to target audiences. As that Facebook widget follows a user around the web, the AI gets better and better at serving the user politically polarizing content shell click on. Mindshare acquired.
Nix went on: For people in the Temperamental personality group, who tend to dislike commitment, messaging on the issue should take the line that showing your ID to vote is as easy as buying a case of beer. Whereas the right message for people in the Stoic Traditionalist group, who have strongly held conventional views, is that showing your ID in order to vote is simply part of the privilege of living in a democracy.
We call this behavioral microtargeting, Nix later told Bloomberg, and this is really our secret sauce, if you like. This is what were bringing to America.
But dont take my word for it. Listen to Nix explain his own methods:
If you dont want to opt in to the secret sauce, what can you do?
On the individual level, bluntly, get good at knowing when youre being sold something. Dont reward intellectual salesmanship that you wouldnt tolerate elsewhere. After all, build a better mousetrap, and Nature will build a better mouse.
From the top-down direction, one way is to work to pass strong privacy regulations. They would need to entail meaningful oversight, and consequences that have teeth when an organization is found in breach of the law. But they also have to be nuanced, because if the government tries to ban something, and then that ban gets challenged in court, the government can lose. That sets legal precedent, just like a win in court would.
Also, heres a thought experiment: Watching Deadpool from your desk chair is not the same as taking in a late-night show in a theater, with the popcorn and the bass and all that. If pirating the data that can reconstruct a movie is the moral and legal equivalent of stealing the movie from a store, then pirating a model that can be used to reconstruct someones personality with enough fidelity to predict and alter their behavior without their consent might also be worth legal attention. Can you consent to be misled, and then vote based on that? Our legislature can be sold ideas, and they enact policy by voting. Whos serving dark posts to Congress, and whats in those posts?
If data feels cold and impersonal, a Cambridge Analytica press release muses, then consider this: the data revolution is in the end making politics (or shopping) more intimate by restoring the human scale.
Thats exactly the problem. It is personal. So much is built on the fact that data can be personal, even when dealing en masse. The salient thing here is that there is an outfit which means to leverage the enormous body of intimately personal data they can gather, in order to conduct large-scale and yet individualized psy ops for the highest bidder. The stakes theyre after are no less than the medium-term fate of nations. Whether or not Cambridge Analytica has done what they claim to have done, Pandoras box is open.
Now read:19 ways to stay anonymous and protect your online privacy
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The Future Of Work: The Intersection Of Artificial Intelligence And Human Resources – Forbes
Posted: at 9:15 pm
Forbes | The Future Of Work: The Intersection Of Artificial Intelligence And Human Resources Forbes Artificial intelligence is transforming our lives at home and at work. At home, you may be one of the 1.8 million people who use Amazon's Alexa to control the lights, unlock your car, and receive the latest stock quotes for the companies in your ... |
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Facebook implements artificial intelligence to identify suicidal users – Washington Times
Posted: at 9:15 pm
Facebook will begin using artificial intelligence and pattern recognition technology in an effort to automatically identify users likely to commit suicide, the company said Wednesday.
The social network has expanded its decade-old suicide prevention tools by making it easier for users both actual and automated to flag account holders at risk of self-harm, Facebook said in a Wednesday press release.
In addition to integrating its current suicide prevention tools across its chat and live-streaming platforms Messenger and Facebook Live, respectively the announcement said the social network is experimenting with artificial intelligence and its potential to identify users likely to attempt suicide.
Based on feedback from experts, we are testing a streamlined reporting process using pattern recognition in posts previously reported for suicide, the announcement said. This artificial intelligence approach will make the option to report a post about suicide or self injury more prominent for potentially concerning posts like these.
The announcement, penned by Facebook product manager Vanessa Callison-Burch, researcher Jennifer Guadagno and Antigone Davis, the companys head of Global Safety, said the company is testing pattern recognition to identify posts as very likely to include thoughts of suicide.
Our Community Operations team will review these posts and, if appropriate, provide resources to the person who posted the content, even if someone on Facebook has not reported it yet, the announcement said.
Suicide claims an average of one life every 40 seconds, according to Facebook, making it the second-leading cause of death among individuals ages 15 through 29. The social network boasted 1.86 billion monthly active users as of the end of 2016, roughly a quarter of which are under the age of 25.
Facebook is in a unique position through friendships on the site to help connect a person in distress with people who can support them, the announcement said. Its part of our ongoing effort to help build a safe community on and off Facebook.
Artificial intelligence and pattern recognition technology will only be used on a limited basis in the U.S. for now, Facebook said. Elsewhere, however, users should expect to see integrated suicide prevention tools while using both Facebook Live and Messenger beginning with Wednesdays roll-out, according to the announcement.
Facebook Live platform was initially introduced to celebrity users in August 2015 before the service was broadened to the rest of its billion-plus account holders the following April. At least three Facebook users have broadcast their suicides using the live-streaming service since the start of 2017, including a 14-year-old girl who allegedly took her own life in January at the end of a two-hour broadcast, Variety reported this week.
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How do we prepare for the Artificial Intelligence Society? – Huffington Post
Posted: at 9:15 pm
At the recent Davos 2017, Klaus Schwab, the founder of the World Economic Forum in conversation with Sergey Brin, co-Founder of Alphabet Google, described his book the 4th Industrial Revolution1 published just a year ago, as rapidly evolving with the rise of artificial intelligence2. While this revolution in fusion of physical, digital, and biological worlds from 3D printing, additive manufacturing, and net shape processing to nanotechnology, bioengineering to deep neural networks were. Underpinned by hyperscaling of infrastructure and advances in consumerization and embedding technology. Most commentators and governments are looking at the positive and negative consequences of these changes both in terms of direct human work impact and indirect associated activity that may be impact from automation and a society with AI.
Transition to an AI Society
The main driver for this revolution is not only the affordability and availability of reliable sensors and computing resources, but also the advancements made in software in particular within the realm of artificial intelligence (eg. machine learning). Andrew Ng recently said there was little if any industry that could not be impacted by AI in some form, and described AI as the new electricity.
While AI is projected to have a pervasive potential for disruption across most industry and business sectors, it is nevertheless important to distinguish the hype from real expectations for such a technology, particularly for practitioners and professionals within our society. Nevertheless, we must heed the cautions expressed by the preeminent minds of our times, never before in the history of humans has there been the availability of hardware and software that will enable humans to contrast intelligent machines. The interconnection of devices when coupled with the automation using these new kinds of technology will have a very serious impact on human employment, privacy, security, social and economic wellbeing that will have huge long-term consequences and implications for the society of human beings.
Earlier revolutions of industry, agrarian, political and social dislocations started in the West and East at different times, which have now become a global phenomenon. Have we reached a point in time where Adam Smith6 economics of the 18th century that defined the basis of the wealth of Nations as economic wellbeing, needs revising in order to accommodate changing value? Changes within our society and habitat, such as aging populations and increasing limitations of global resources and concerns over greenhouse gases, etc. will inevitably present us with new challenges and hurdles for humankind to overcome often in unrealistic timeframes.
What will be the new jobs in this new world and how will these kinds of new technology help to create new jobs, which will be balanced in some manner given that the distribution of work and wealth will change drastically in the next few decades. Pursuing laissez-faire economic policies with minimal intervention on peoples rights and wellbeing may need to be rethought as changes are brought upon the very mechanisms of wealth creation and sharing are integrated, and even controlled, by machine automation.
Professor Mark Skilton, Dr Felix Hovespian
Forthcoming book: The Fourth Industrial Revolution: An Executive Guide to Intelligent Systems, 2017 Palgrave Macmillan. Professor Mark Skilton. Dr Felix Hovespian.
1. Klaus Schwab, The 4th Industrial Revolution, World Economic Forum, 2016 ISBN-13 978-1-944835-00-2
3. Dr. Andrew Ng: Artificial Intelligence is the New Electricity, January 25 2017. Stanford MSx Future Forum https://www.youtube.com/watch?v=21EiKfQYZXc&feature=youtu.be&a (Dr. Andrew Ng, VP & Chief Scientist of Baidu; Co-Chairman and Co-Founder of Coursera; and an Adjunct Professor at Stanford University)
5. Adam Smith: The Father of Economics, Sept 7 2016 , Investopedia http://www.investopedia.com/updates/adam-smith-economics/
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Baidu Ventures partners with Comet Labs as both double down on artificial intelligence – TechCrunch
Posted: at 9:15 pm
TechCrunch | Baidu Ventures partners with Comet Labs as both double down on artificial intelligence TechCrunch Baidu Ventures exists on the front-lines of the Chinese search giant's push to brand itself as an artificial intelligence company. In an effort to bridge the AI ecosystems of China and the United States, Baidu Ventures is partnering with Comet Labs, a ... |
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NVIDIA’s Artificial Intelligence Opportunity in 1 Chart – Motley Fool
Posted: at 9:15 pm
NVIDIA (NASDAQ:NVDA) was one of the hottest tech stocks of 2016, jumping 230% over the past 12 months. The company makes the vast majority of its revenue from gaming -- about 62% in the fiscal fourth quarter 2017 -- but NVIDIA is much more than just a gaming processor company.
The artificial intelligence (AI) market is quickly expanding, and NVIDIA is positioning itself to make big gains in the space. According to an investor note published by Goldman Sachs' Toshiya Haria couple of months ago, NVIDIA's total addressable market in AI and deep learning could be as big as $5 billion to $10 billion -- out of a total market of $40 billion.
Take a look:
Data source: Goldman Sachs. Chart by author.
Hari mentioned that NVIDIA already has a lead in the AI space and that the company's competition "continues to face high barriers to entry." He went on to add that NVIDIA already holds nearly 90% of the market for chips that are used for training tasks in machine learning (referring to the company's GPUs).
NVIDIA's position in the burgeoning AI market market comes from several of the company's products. Its Drive PX 2 supercomputer uses deep learning to process image information for self-driving vehicles and help them decide how they should react in certain situations.
More than 80 automakers and Tier 1 automotive suppliers already use a version of Drive PX, including Tesla. The electric-auto maker is rapidly moving toward a self-driving car future and has already added key driverless car technologies -- including NVIDIA's computers -- to make it a reality.
But the company isn't satisfied just with using its GPU-based AI computers for autonomous driving. NVIDIA's DGX-1 supercomputer server uses machine learning systems to process information faster than previous deep learning machines of its kind, and is currently being used by SAP for enterprise solutions for 320,000 customers.
NVIDIA says that its latest Pascal chip architecture is"purpose-built for AI," and other major tech companies have already taken notice. BothIBM and Microsoft are using NVIDIA's GPUs for some of their AI services as well."
While NVIDIA's AI opportunity is huge, investors should know one thing: AI makes up only a small percentage of revenue right now.
In the fiscal fourth quarter 2017, NVIDIA brought in just $296 million from its data center division -- 13% of total revenue -- and even its automotive business (which includes the Drive PX 2 AI supercomputer) brings in less than 6% of total revenue.
That means the company will need to continue releasing new hardware and adding more customers to reach its full AI potential. But at this point, NVIDIA is already well on its way to fully tapping into the AI market, and it's doing so at the perfect time.
This year may be one of the best years to invest in AI, as tech companies and governments around the world are ramping up investments in artificial intelligence. NVIDIA's current position in AI, potential market share, and focus on new AI hardware should push the company to the top of the list for anyone looking to invest in AI over the long term.
Teresa Kersten is an employee of LinkedIn and is a member of The Motley Fools Board of Directors. LinkedIn is owned by Microsoft. Chris Neiger has no position in any stocks mentioned. The Motley Fool owns shares of and recommends Nvidia and Tesla. The Motley Fool has a disclosure policy.
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Artificial intelligence: could pharma lead the way? – PMLiVE
Posted: at 9:15 pm
PMLiVE | Artificial intelligence: could pharma lead the way? PMLiVE Chris Cooper A rare opportunity now exists for the pharmaceutical industry to play its part in driving customer behaviour with a digital marketing approach that the world is fast becoming familiar with, and will soon be reliant on - artificial ... |
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Georges St-Pierre Takes Aim at Immortality in Title Shot Against Michael BIsping – Bleacher Report
Posted: at 9:14 pm
Josh Hedges/Zuffa LLC/Getty Images Chad DundasMMA Lead WriterMarch 1, 2017
UFC President Dana White announced Wednesday that Georges St-Pierres return to the Octagon will be a middleweight title fight against Michael Bispingand, boy, is that going to be an unpopular decision.
Of all the likely candidates for St-Pierres returnincluding superfights against Anderson Silva or Conor McGregorBisping was unilaterally regarded as the least appealing.
In the wake of Whites appearance on ESPNs SportsCenter to confirm this fight, early reviews have been mostly negative:
This unrest is nothing against the 185-pound champion himself but, rather, a compliment to the overall strength of the middleweight division. With top contenders like Yoel Romero and Jacare Souza already beating down Bispings door there was just no good reason to further stymie that divisions already slow-motion title picture.
That is, except for the two reasons that trump all else right now in the eyes of this fight company and these fighters: Money and immortality.
Since winning the title with a surprise knockout of Luke Rockhold at UFC 199 in June 2016, Bisping has eschewed the UFCs official rankings in favor of trying to chase down lucrative matchups for himself. Hes defended the title just once since, against Dan Henderson at UFC 206 four months ago.
You cant blame Bisping for this approach. At 37 years old, hed long been considered a nice cog in the middleweight machine, but not championship material. Here hes got an unprecedented and unexpected chance to earn a nice bonus after 11 years and nearly 30 fights worth of service for the UFC.
And for GSP?
Well, what he gets in his return to the Octagon after a three-year absence is a potentially winnable championship fight, a nice payday and a chance at the history books.
If St-Pierre is able to return to action at 36 years old and win another UFC title in a weight class above his natural division, there will simply be no argument against anointing him the greatest MMA fighter of all time.
Hes already routinely mentioned on the short-list of contenders for that honor alongside former middleweight champion Anderson Silva and former light heavyweight champ Jon Jones. Defeating Bisping would definitively put GSP over the top in that three-horse raceat least for the time being.
Silvas claim to the throne has taken a big hit in recent years.
Back-to-back losses to Chris Weidman at UFCs 162 and 168 signaled the end of his career as a truly elite middleweight, but had Silva walked away then he might still be able to lay credible claim to GOAT status.
Unfortunately, he soldiered on and has gone just 1-4-1 dating back to the beginning of 2013 (that record includes the Weidman losses). His only official win in that span came three weeks ago, in a controversial unanimous decision against middling contender Derek Brunson.
Perhaps most damaging, Silvas win over Nick Diaz at UFC 183 was overturned after he tested positive for two banned substances. Its tough to make any case for greatest-of-all-time seriously from a guy who has tested dirty for performance enhancers.
Jones, meanwhile, is the most gifted athlete and strategist the UFC has ever seen, but has had a hard time keeping himself on the organizations active roster of late.
Hes managed to fight just once a year the past three years and has missed significant time, first while sorting out legal issues stemming from a hit-and-run accident and then after himself testing positive for banned substances during the lead-up to a fight against Daniel Cormier at UFC 200.
Joness claim that the positive test resulted from a tainted dietary supplement was later substantiated by the US Anti-Doping Agency, but as of this writing hes still out serving a one-year suspension.
If Jones can return and win back his light-heavyweight title at age 30 hell still have plenty of time to move past both Silva and St-Pierre for consideration as best ever. That future has never appeared less secure than now, however, as Jones out-of-the-cage transgressions have taken on considerable momentum and have left him facing what might be his last chance with UFC ownership.
For the time being, St-Pierre leads his two closest competitors by a nose. Even before he makes this comeback, the case against him as greatest of all time must be made primarily on style points.
From 2006 to his announced break from the sport at the end of 2013with the exception of roughly one year spent without the title after a fluke loss to Matt Serra at UFC 69he ruled the UFC welterweight division with merciless zeal. He defeated nine consecutive challengers, more often than not taking out the best 170-pound fighters the UFC could find without so much as losing a round.
Critics called it boring, but the truth was, it was amazing. Without any organized background in wrestling, St-Pierre transformed himself from a stand-up oriented, Kyokushin karate stylist to one of the most dominant grapplers in Octagon history.
He beat wrestlers like Matt Hughes, Jon Fitch and Johny Hendricks. He beat potent strikers like Nick Diaz and Carlos Condit. He beat submission aces like Serra (in their rematch at UFC 83), BJ Penn and Jake Shields.
It didnt matter what they did. St-Pierre beat them all.
Meanwhile, his built-in Canadian audience turned him into the UFCs single biggest pay-per-view draw to that point. It was a different time for the UFC, but GSPs PPV numbers are still staggering. He sold an estimated 625,000 PPVs for his fight against Fitch at UFC 87, 770,000 against Dan Hardy at UFC 111 and 800,000 against Shields at UFC 129.
In todays UFC there is next to no one who can consistently provide those kinds of numbers, outside of McGregor.
Thats one place St-Pierres detractors fall flat. The notion that MMA fighters need to be exciting only exists because of the PPV model. Conventional wisdom preaches that fighters need to impress audiences in order to convince them to shell out $60 to watch them fight.
But GSP never had a problem with that. In fact, he did it better than anybody else from his era.
Can he still? That remains to be seen.
His accomplishments to this point are nearly peerless, however. Now, if St-Pierre can return from his lengthy hiatus, defeat Bisping and win another UFC title in a different weight class?
With all due respect to Silva and Jonesand to borrow a phrase from longtime MMA announcer Michael Schiavellothats good night, Irene.
[Estimated pay-per-view numbers courtesy Dave Meltzer's ProWrestling Observer, as compiled at MMA Payout.]
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Georges St-Pierre Takes Aim at Immortality in Title Shot Against Michael BIsping - Bleacher Report
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Heart tissue cryogenics breakthrough gives hope for transplant patients – The Guardian
Posted: at 9:13 pm
Freezing and rewarming sections of heart tissue successfully raises hopes for doing the same for the entire organ. Photograph: Sebastian Kaulitzki/Alamy
Scientists have succeeded in cryogenically freezing and rewarming sections of heart tissue for the first time, in an advance that could pave the way for organs to be stored for months or years.
If the technique scales up to work for entire organs and scientists predict it will it could save the lives of thousands who die each year waiting for transplants.
The work is being hailed as a major development in the field of cryopreservation as it marks the first time that scientists have been able to rapidly rewarm large tissue samples without them shattering, cracking or turning to a pulp. The US team overcame this challenge by infusing the tissue with magnetic nanoparticles, which could be excited in a magnetic field, generating a rapid and uniform burst of heat.
Kelvin Brockbank, chief executive officer of Tissue Testing Technologies in Charleston, South Carolina and a co-author, said: It is a huge landmark for me. We can actually see the road ahead for clinical use and getting tissues and organs banked and into patients.
Currently, donor organs such as hearts, livers and kidneys must be transplanted within hours because the cells begin to die as soon as the organs are cut off from a blood supply. As a result, 60% of the hearts and lungs donated for transplantation are discarded each year, because these tissues cannot be kept on ice for longer than four hours.
Recent estimates suggest that if only half of unused organs were successfully transplanted, transplant waiting lists could be eliminated within two to three years. The latest paper has been hailed as a significant step towards this goal.
Mehmet Toner, a professor of bioengineering who is working on cryopreservation at Harvard Medical School, said: Its a major breakthrough. Its going to catalyse a lot of people to try this in their laboratories. Im impressed.
Cryopreservation has been around for decades, but while it works well for red blood cells, sperm and eggs, scientists have come up against a barrier for samples with a volume larger than around one millilitre.
Previously, larger samples have been cooled successfully using a technique known as vitrification, in which the tissue is infused with a mixture of antifreeze-like chemicals and an organ preservation solution. When cooled to below -90C (-130F), the fluid becomes a glass-like solid and prevents damaging ice crystals from forming.
The real problem has been the thawing process. Unless the rewarming occurs rapidly and uniformly, cracks will appear in the tissue and tiny ice crystals suddenly expand, destroying cellular structures.
We can freeze tissue and it looks good, but then we warm it and there are major issues, said Toner.
The latest work scales up cryopreservation from one millilitre to about 50ml, and the scientists said they believe the same strategy is likely to work for larger skin transplants, sections of ovarian tissue and entire organs.
John Bischof, professor of mechanical engineering at the University of Minnesota and the senior author of the study, said: We have extremely promising results and we believe that were going to be able to do it but we have not yet done it.
Brockbank and colleagues previously attempted and failed to use microwave warming to generate an even thawing. It failed dreadfully due to the development of hotspots in the tissue, he said.
In the latest paper, published in the journal Science Translational Medicine, the team describe the new nano-warming technique. Pig heart valves and blood vessels were infused with a cryoprotectant solution mixed with iron oxide nanoparticles, coated in silicon to make them biologically inert, and the samples were cooled in liquid nitrogen to -160C (-256F).
For thawing, the sample was placed inside an electromagnetic coil, designed to generate an alternating magnetic field. As the magnetic field is flipped back and forth, the particles jiggle around inside the sample and rapidly and uniformly warm tissue at rates of 100 to 200C per minute, 10 to 100 times faster than previous methods.
In tests of their mechanical and biological properties, the tissues did not show any signs of harm, unlike control samples rewarmed slowly over ice. The researchers were also able to successfully wash away the iron oxide nanoparticles from the sample following the warming although said that further safety testing would be required before the technique could be used in patients.
The team are now testing the technique on rabbit kidneys and human allografts, which are combinations of skin, muscle and blood vessels from donors.
That will be our first trial with human tissues, said Brockbank. If that is successful, we would then progressively move to structures such as the human face for banking and for hands for banking as well as digits.
However, he added that it was difficult to put a timeline on when the developments might have a clinical impact, as this depended on regulatory approval as well as overcoming significant scientific challenges.
The scientists acknowledged that their work may attract interest from the cryonics industry, which promises to freeze the bodies or heads of clients after their death in the hope of bringing them back to life in the future, when medicine has advanced.
There is a certain intellectual connecting of the dots that takes you from the organ to the person... I could see somebody making this argument, said Bischof, but added these ambitions were not science-based as unlike with organs, the person would already be dead when frozen.
Clive Coen, professor of neuroscience at Kings College London, described the technique as ingenious. If the technique can be scaled-up to large organs such as kidneys, the contributions to the field of organ transplantation could be immense, he said. Such painstaking and careful research is to be applauded and must not be confused with wishful thinking about sub-zero storage and subsequent reanimation of a human body, as envisaged by the cryonics industry
Almost 49,000 people in Britain have had to wait for an organ transplant in the past decade and more than 6,000, including 270 children, have died before receiving the transplant they needed, NHS statistics reveal.
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Heart tissue cryogenics breakthrough gives hope for transplant patients - The Guardian
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Keegan Macintosh-British Columbia Guy Signs First Canadian Cryonic Contract – E Canada Now
Posted: at 9:13 pm
A B.C. man who is challenging the provinces laws on the preservation of the body after death has signed a groundbreaking cryonic contract. Keegan Macintoshis believed to be the first person to sign a deal with a Canadian provider to keep his body in a state of permanent suspension.
The four-page contract between Keegan Macintosh and the Lifespan Society of B.C. is accepted to be the first run through a Canadian has marked with a neighborhood supplier to keep their body in a condition of lasting suspension.
The agreement is the most recent turn in a strange B.C. Preeminent Court confrontation over the regions Cremation, Interment and Funeral Services Act.
Macintoshs claim says the province is the only place on theplanet to fugitive cryonics.
The issue of cryonics increased overall consideration this month when a British judge allowed the last wishes of a 14-year-old who composed a letter before kicking the bucket of malignancy asking the court to let her mom cryogenically safeguard her body.
The decision made room for the young ladys remaining parts to be taken to an office in the U.S. to begin the conservation procedure at a cost of more than $62,000.
Various Canadians have marked cryonic safeguarding manages U.S. suppliers, however, Lifespan president Carrie Wong says the agreement with Macintosh is accepted to be the first of its kind in Canada.
Mac has altered his unique explanation of claim to mirror the marking of an agreement. Wong said the general public is currently holding up to perceive how the Crown reacts.
Wong said, If theyre really not interested, then anyone in B.C. can go into a cryonics arrangement.
As indicated by the terms of the arrangement, Lifespan will supplant Macintoshs blood with a sort of liquid catalyst to avoid ice gems framing when the body is cooled.
The general public additionally consents to suspend Macintoshs remaining parts at ultra-low temperatures.
Consequently, Macintosh will pay $30 a year.
The agreement gives a progression of capabilities around revival, beginning with the finishing date.
However, Lifespan additionally concurs that when in Lifespans best judgment, it is determined that attempting resuscitation is in the best interests of the cryopreserved member, Lifespan shall attempt to resuscitate (Macintosh).
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Keegan Macintosh-British Columbia Guy Signs First Canadian Cryonic Contract - E Canada Now
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