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Category Archives: Transhuman News

Families offer to help with bones' DNA tests

Posted: October 8, 2012 at 1:23 pm

During the last three years, a skull and two femur or thigh bones have been found off the Wexford and Waterford coasts.

Garda authorities were informed by their detectives that special DNA testing in England was required as testing in Ireland had not managed to extract the DNA and identify the remains.

Garda were also told it is possible the remains may be some of the crew of either the Pere Charles, the Maggie B or the Honey Dew II.

The bodies of nine men from those tragedies were never recovered.

Garda say the cases are still being actively investigated and the matter has been raised in the Dil.

John Hennessy, a brother of the Pere Charles skipper Tom Hennessy, said the remains are lying in storage in a fridge in Dublin and are still unidentified.

He told RT News that families would be willing to discuss paying to have the bones tested if it was only financial considerations that were stalling the investigation.

Garda were told last year the cost could be up to 12,000 but that included testing on other bones, the identity of which have since been ascertained, so the cost would now be lower.

Mr Hennessy said he believes the Government has handled the situation badly, saying all that the families wanted was to have the two bones and the skull sent to England to see if the DNA can be extracted.

Garda say inquires to establish the identity of the human remains have not yielded any positive results so far.

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Forensic Anthropologist Uses DNA to Solve Real-Life Murder Mysteries in Latin America

Posted: at 1:23 pm

Argentinean Mercedes Doretti has successfully identified the remains of hundreds of Central American immigrants who have perished on their dangerous journey north

By Brendan Borrell

DIGGING FOR JUSTICE: Forensic anthropologist Mercedes Doretti led a team of researchers identifying remains of Los Desaparecidos--the disappeared ones--in her native Argentina. Her work there continues today, as evidence she personally collected in the 1980s is still making its way through the country's legal system. Image: Courtesy of Richard Renaldi

"Seora, go and search for yourself." With those words, Mexican authorities sent away the grieving mother seeking clues about her daughter's killer. The year was 2001, after those authorities had discovered the bodies of eight young women in a cotton field near Ciudad Jurez on the Texas-Mexico border, across the Rio Grande from the U.S. city of El Paso. Police were unlikely to solve their cases, just like those of the hundreds of women who had been sexually abused, mutilated and killed in this lawless town, where this year alone another 60 women and girls have been murdered. The government's handling of the "Campo Algodonero" murders stood out as an egregious violation of human rights for the way the authorities botched the case and mishandled the women's remains.

The victims' mothers even came to doubt that the remains authorities had given them were their own children. In December 2003 they began working with Mercedes Doretti, a New York-based forensic anthropologist and co-founder of the Argentine Forensic Anthropology Team to get help in identifying the bodies.

Doretti's work in Ciudad Jurez revealed that law enforcement had misidentified three of the eight remains furnished, and her report to the Inter-American Court of Human Rights led in 2009 to an order for reparations to all the families and a condemnation of the Mexican justice system. That small victory cemented Doretti's resolve to probe deeper. She now knew that dozens of other bodies had no possible matches to local families. Where had these other victims come from?

Doretti, a stylish woman in her 50s, has spent her life supporting human rights. She studied anthropology in Buenos Aires, during the height of Argentina's "Dirty War," when the right-wing regime kidnapped, tortured and murdered some 20,000 students, activists, journalists and guerrillas. Her team's work identifying remains of the Desaparecidosthe disappeared onescontinues today, and evidence she personally collected in the 1980s is still making its way through the country's legal system. In 2007 the MacArthur Foundation awarded her a "genius grant" for her work investigating human rights abuses around the world, and she serves as a Chairman of the Board of Trustees of the United Nations Voluntary Fund for Victims of Torture.

Doretti suspected that some of the unidentified bodies in Mexico may have been migrants journeying north from Central America, and in 2009 she established the Missing Migrants project. The full scope of the problem is hard to pin down, but some 200 migrants die of exposure each summer in southern Arizona alone. Mexico's criminal gangs have kidnapped many more for extortion or murdered and buried these victims in mass graves. Doretti has created a network of forensic DNA banks in El Salvador, Honduras and Chiapas, Mexico and recently announced her first positive identifications from remains recovered in Texas and Arizona. "It's amazing what she's doing," says Bruce Anderson, forensic anthropologist with the medical examiner's office in Pima County, Arizona.

Scientific American met Doretti at her organization's spartan one-room office in Brooklyn's DUMBO neighborhood. Edited excerpts follow.

When the Argentinean dictatorship collapsed in 1982, you still thought that you might follow an academic anthropology path. How did you get introduced to forensics? I was at a demonstration against the International Monetary Fund in January 1984, and one of my friends came and said: "There's a gringo who wants to exhume disappeared people." As it happened, the American Association for the Advancement of Science had sent a scientist named Clyde Snow down to train people in forensics, but the Argentinean Anthropology Association initially did not want to get involved directly. Snow didn't have anybody to work with. Frankly, it sounded very strange to me. But after meeting him the next day, I realized everything he was saying made total senseto apply the techniques of traditional archaeology and biological anthropology into the forensic field so that we will be able to recover and identify the remains of Los Desaparecidos in the proper way.

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Forensic Anthropologist Uses DNA to Solve Real-Life Murder Mysteries in Latin America

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DNA Sequencing Market Growth Driven by Top 10 Companies and Technologies

Posted: at 1:23 pm

ReportsnReports.com adds new market research report Top Ten Companies in DNA Sequencing to its store. Global sequencing products market is forecast to reach $6.6 billion by 2016.

Dallas, Texas (PRWEB) October 08, 2012

The goal of this report is to provide a more in-depth look at the top tier DNA sequencing companies as well as some of the second tier companies to look for in the near future, and to note the technological changes within the DNA sequencing industry that are sure to play a role in the years to come.

More specifically, the objectives include identifying companies that are considered the leaders in their field and the technological means these companies are using to exploit their markets and dominate their field.

Key technology points explored include:

Other major factors used to determine top companies in the field include:

INTENDED AUDIENCE

This study will be of particular interest to life-science research tools suppliers, pharmaceutical, diagnostics, nanotechnology, bioinformatics, semiconductor, and biotechnology companies. It will also be valuable to companies involved in genome sequencing projects, sequencing centers, manufacturers of microarrays, suppliers of molecular diagnostics assays, bioinformatics companies, and cancer researchers and clinicians. As this report is a profiling of top companies in the DNA sequencing field, the main audience should also include executive management personnel and marketing and financial analysts.

SCOPE

The scope of this report is focused on a select 10 companies in DNA sequencing, and the key areas in the field that are driving industry growth allowing these companies to succeed. These areas include Sanger, next-generation, and emerging sequencing technologies; the markets for sample preparation products, sequencing instruments and consumables; and bioinformatics and sequencing services. A key area BCC also explores is industry structure, noting strategic alliances and acquisitions along with pertinent patent information.

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DNA Sequencing Market Growth Driven by Top 10 Companies and Technologies

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8 new susceptibility loci for eczema identified

Posted: at 1:22 pm

London, October 8 (ANI): In a new study, researchers have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population.

The findings by researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues, advance our understanding of the genetic basis of the skin disorder, which affects millions of children and adults around the world.

Atopic dermatitis - often called eczema - is a chronic, relapsing inflammatory skin condition affecting as much as one-fifth of children and 1-3 percent of adults in industrialized countries.

Those with the condition have skin that reacts easily to the environment and becomes flaky and itchy. While treatment can alleviate some of these symptoms, current techniques remain ineffective in many cases, due in part to a limited scientific understanding of the origins of the condition.

The research group set out to shed light on these origins using a genome-wide association study (GWAS), an approach which identifies gene loci associated with a particular trait. With its strong genetic basis, atopic dermatitis is well suited to the GWAS approach.

Three previous GWAS on European and Chinese populations identified 7 loci associated with the condition, but no such studies have been conducted on Japanese people.

To fill this gap, the group conducted a thorough GWAS on 1472 subjects with atopic dermatitis and 7971 controls from among the Japanese population, and then validated their results in a separate study on 1856 subjects with atopic dermatitis and 7021 controls.

Analyzing a total of roughly 600,000 genetic variants (called Single Nucleotide Polymorphisms or SNPs), they identified 8 new genetic regions associated with atopic dermatitis and confirmed the 7 loci observed in earlier studies.

Among these regions, they identified variants at the IL1RL1/IL18R1/IL18RAP and human leukocyte antigen (HLA) loci, both of which have been associated with bronchial asthma in recent GWAS.

The group's findings thus suggest that atopic dermatitis and asthma have overlapping susceptibility regions, and thus that these regions contain common genetic factors for many allergic diseases.

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8 new susceptibility loci for eczema identified

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Krugman's MMMF Question

Posted: at 1:20 pm

By Mark Thornton

Paul Krugman attacked Ron Paul, Paul Ryan, and "honest money" and also took a shot at Austrian economists on his blog recently. He called honest money a "Ron Paul dog whistle" and then went on to query Austrian economists on their position on money-market mutual funds (MMMF). He doesn't expect a serious answer.

How do the Austrians propose dealing with money market funds? I mean, it has always been a peculiarity of that school of thought that it praises markets and opposes government intervention but that at the same time it demands that the government step in to prevent the free market from providing a certain kind of financial service. As I understand it, the intellectual trick here is to convince oneself that fractional reserve banking, in which banks don't keep 100 percent of deposits in a vault, is somehow an artificial creation of the government. This is historically wrong, but maybe the actual history of banking is deep enough in the past for that wrongness to get missed.

But consider a more recent innovation: money market funds. Such funds are just a particular type of mutual fund and surely the Austrians don't want to ban financial intermediation (or do they?). Yet shares in a MMF are very clearly a form of money you can even write checks on them created out of thin air by financial institutions, with very few pieces of green paper behind them.

So are such funds illegitimate?

In the Austrian view MMMF are not technically money and so deposit holders do not hold full reserves, but rather invest those deposits in short-term commercial paper. MMMF can lose value and owners may get back less than they deposited without the deposit holder going bankrupt. Technically they are not instantly redeemable and are not a final means of payment.

According to Joseph Salerno,

Although MMMF share accounts at first glance look like MMDAs [money-market deposit accounts], they are clearly excludable from the TMS [true money supply], because they are neither instantly redeemable, par value claims to cash, nor final means of payment in exchange. This requires a brief explanation of the nature of MMMFs.

Each MMMF share represents a claim to a pro rata share of a managed investment portfolio containing short-term financial assets, such as high-grade commercial paper, certificates of deposit, and U.S. Treasury notes. Although the value of a share is nominally fixed, usually, at one dollar, the total number of shares owned by an investor (abstracting from reinvested dividends) fluctuates according to market conditions affecting the overall value of the fund's portfolio. Under extreme circumstances, such as a stratospheric rise in short-term interest rates or the bankruptcy of a corporation whose paper the fund has heavily invested in, the fund's investors may well suffer a capital loss in the form of an actual reduction of the number of fixed-value shares they own. Unlike a check drawn on a demand deposit or MMDA, therefore, an MMMF draft does not simply represent a direct transfer of current claims to currency, but a dual order to the fund's manager to sell a specified portion of the shareowner's asset holdings and then to transfer the monetary proceeds to a third party named on the check. Note that the payment process is not finally completed until the payee receives money, typically in the form of a credit to his demand deposit. (Austrian Economics Newsletter 6.4)

No Paul, we do not want to ban MMMF.

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Krugman's MMMF Question

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PICKET: EPA told human test subjects – 'there's a possibility you may die from this'

Posted: at 1:20 pm

Steven Milloy's lawsuit against the EPA has gone forward into federal court. As I wrote in a previous post, Milloy, a biostatistician and securities lawyer who runs the site junkscience.com, is suing the Environmental Protection Agency overwhat he discovered through evidence from a Freedom of Information Act request.

Milloy found that "disturbing experiments" conducted for the EPA "are exposing humans to inhalable particulates" that the agency has said are deadly, theNational Legal and Policy Center noted.

Senator Jim Inhofe, Oklahoma Republican and ranking member of the Environmental Public Works Committee, is calling for a hearing to investigate this matter further.

According to Milloy, the EPA declared to a federal court that it asks human guinea pigs to risk their lives for regulatory purposes at $12 per hour.:

EPA responded (Thursday) to our emergency motion for a temporary restraining order (TRO) against its ongoing human experiment (called CAPTAIN) involving the air pollutant known as PM2.5.

In the declaration of Martin W. Case, the EPA clinical research studies coordinator for CAPTAIN, Case claims he verbally warns study subjects before the experiment as follows:

My first approach after being introduced to the subject by the medical station staff is to ask the subject if they have read the consent form. The subjects for CAPTAIN have been given the informed study consent form on a previous visit, and, they are also given the same consent to read again if they have not read the consent the day of the training

I provide participants with information about fine particles (PM2.s). I say that PM2.s are particles so small that they are able past through your airways and go deep into your lungs, these particles are so small that your usual lining and cilia of your airways are not able to prevent these particles from passing into your lungs, Therefore, if you are a person that for example lives in a large city like Los Angeles or New York, and its been a very hot day, and you can see the haze in the air, and you happen to be someone that works outside, and if you have an underlying unknown health condition, or, you may be older in age; the chances are that you could end up in the emergency room later on that night, wondering whats wrong, possibly having cardiac changes that could lead to a heart attack; there is the possibility you may die from this

Heres the analysis of Cases remarkable admission that is, if we can even rely on Cases declaration:

Prohibition on human sacrifice. Every law, regulation and code developed since World War II strictly prohibits human sacrifice (i.e.,significant injury or death) for no health benefit to the patient (the wage of $12 per hour does not count as a benefit). EPA employee Case explicitly admits in this declaration that short-term exposure to PM2.5can be lethal.And though Case attempts to distance this warning from the experiment by explaining the risk in terms of a person living in a large city like Los Angeles or New York, EPA states in its IRB application for approval of CAPTAIN, The particle burden, on a mass basis presented to the volunteer will not exceed an exposure an individual receives over a 24 hour period while visiting a typical urban center in America on a smoggy day. Moreover, EPA has repeatedly stated in numerous regulatory documents and public statements that there is no safe level of exposure to PM2.5 and that any exposure to PM2.5 can kill within hours or days.

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PICKET: EPA told human test subjects - 'there's a possibility you may die from this'

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ADP Broadens its Human Capital Management Offer to Help Midsized Companies Gain a Competitive Edge

Posted: at 1:20 pm

CHICAGO, Oct. 8, 2012 /PRNewswire/ -- ADP, a leading provider of human capital management solutions, today unveiled its next-generation ADP Workforce Now cloud-based platform for midsized organizations. The company showcased its new platform at the annual HR Technology Conference & Exposition in Chicago. This enhanced platform broadens ADP's lineup of human capital management (HCM) services by providing midsized companies with access to more sophisticated tools to manage their workforce. As midsized companies struggle to compete in tough economic times, ADP Workforce Now enables businesses to be more strategic in how they manage their employees while reducing time spent on administrative tasks.

To view the multimedia assets associated with this release, please click: http://www.multivu.com/mnr/58119-adp-enhances-human-capital-management-platform-for-midsized-companies

(Photo:http://photos.prnewswire.com/prnh/20121008/MM82922LOGO )

According to a recent survey by the ADP Research InstituteSM, only 15% of midsized business owners and executives are confident the U.S. economy will improve over the next 12 months compared to 52% who believe it improved during the last four years. Despite this pessimistic outlook, 43% plan to hire an average of 18 new employees in the next year.

The same ADP Research Institute study entitled, "Top Concerns of Business Leaders in the Post-2008 Economy," revealed the top three business concerns on the minds of midsized business owners are:

Of particular interest is the area of increased government regulation, where 81% of midsized business owners believe their business is in compliance with tax and labor regulations. Yet, 33% reported having incurred unintended expenses such as fines or penalties in the last year due to noncompliance not once, but an average of 6.4 times. Midsized companies can ill afford such preventable expenses and need HCM tools that can help business owners reduce risks and operate more efficiently.

"We're thrilled to unveil our enhanced platform for midsized businesses and understand companies of all sizes need access to sophisticated HCM tools," said Jessica Saperstein, Division Vice President of Strategy and Business Development at ADP. "Our newly enhanced ADP Workforce Now platform gives midsized companies greater controls in an all-in-one package so they can do more to confront human resources challenges."

The ADP Workforce Now platform is a key component of ADP's fast-growing HCM portfolio, which includes ADP Vantage HCMSM for large organizations and ADP GlobalView for multinational organizations. ADP recently announced its HCM services now support more than 30,000 clients worldwide.

"I've used ADP Workforce Now for years to efficiently manage my organization's employees, and I'm excited about how the new functionality on this evolving platform provides even greater control over HR tasks," said Tom Aldrich, Vice President/Human Resources Director, at Teche Federal Bank, an existing ADP Workforce Now client in New Iberia, La. "In fact, the technology behind ADP Workforce Now allows me to perform most human resources activities from anywhere with an Internet connection, which is critical during hurricanes and other natural disasters that periodically impact the Gulf Coast."

Designed for the Midmarket's Evolving Needs

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ADP Broadens its Human Capital Management Offer to Help Midsized Companies Gain a Competitive Edge

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A Quick Primer On Futurist-Level Foresight

Posted: at 1:20 pm

Anyone raising a child with the benefits of the digital world doesn't have to look past those tiny fingertips tapping their own apps to realize how quickly we're transitioning.

Theoretical physicist and futurist Dr. Michio Kaku argues that humankind is at a turning point in history. He claims that in this century, we are going to make a shift from the "Age of Discovery" to the "Age of Mastery," a period in which we will move from being passive observers of life and nature to its active choreographers. According to Kaku, robots with human-level intelligence may finally become a reality, and in the ultimate stage of mastery, we'll even be able to merge our minds with machine intelligence. It's how we harness this mastery that will matter.

The science fiction is becoming fact. During a recent visit to Google headquarters, California Gov. Jerry Brown signed legislation to allow autonomous vehicles to operate on the state's roads. Brown touted the signing of the bill as turning today's science fiction into tomorrow's reality. California is the third U.S. state to legalize self-driving cars, following Nevada and Florida, where similar laws earlier were passed this year.

This is just the beginning. We need to be ready for the next set of intelligent innovation, in any field. Hospitals are embracing robotic surgery, and patients are choosing it more and more for many procedures. Robotic-assisted laparoscopic radical prostatectomy, is minimally-invasive, laparoscopic surgery, and has become the standard of care for prostate cancer patients. It offers lower morbidity, less pain, less blood loss and increased precision.

Education too needs to evolve to prepare people for an integrated world, where science converges with every area of practice and development. People training in or committed to a single discipline in a traditional manner won't succeed in tomorrow's marketplace. For more than 30 years, the Fisher Program in Management and Technology has combined two of Penn's greatest assets into one educational experience: Penn Engineering and The Wharton School. Schools that fail to offer true cross-disciplinary study are going to fall behind to create future leaders of a converged world. And leaders who fail to create cross-functional, cross-industry workforce will lose to their competition.

It is the leader's responsibility to prepare his or her organization for what lies ahead--and that will mean changes in what we are doing now to break down the silos and create multi-disciplinary teams--in order to prepare for the unknown.

The underlying, critical element of achieving and maintaining convergence in the modern organization is nothing less than individual leadership. It takes leaders with perseverance and courage to build and implement the cross-functional management culture with the tenets of converged disciplines.

It is a continual evolution and revolution of concepts and opportunities that reflect contemporary and future business operations and objectives.

An essential part of this transition requires both left-brained (analytical) and right-brained (creative) talent and culture. Leaders of the future will approach this collaboration challenge by defining cross-functional teams as personas'. These are roles that one assumes or displays in society or the workplace. Their skills and behaviors influence their interactions with other people. Some personas are analytical, some are creative, and others are a combination. A few personas are as follows:

However, to sustain product and business innovation, leaders must build a flexible culture that can attract and empower a wide variety of talent. It is all too easy for organizations to fall into the analysis trap and focus on left-brain skills like process, measurement, and execution.

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A Quick Primer On Futurist-Level Foresight

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SpaceX to launch cargo ship for space station delivery

Posted: October 7, 2012 at 10:20 pm

CAPE CANAVERAL, Florida A privately owned rocket was poised to blast off Sunday night on the first of a dozen space station supply missions under a mega-contract with NASA.

It will be the second time that the California-based SpaceX company tries to launch a Dragon capsule to the International Space Station.

Last May, a test flight went well. Now the real work is about to begin under a $1.6 billion contract between NASA and SpaceX. This will be the first of 12 resupply missions under that contract.

"Are you ready to hear the (hash)Dragon roar!" SpaceX said in a Twitter update.

SpaceX raised the Falcon rocket, vertically, at its launch pad Sunday afternoon in advance of the 8:25 p.m. liftoff. Forecasters said there's a 40 percent chance that storm clouds or rain could interfere. The good news was that a piece of space junk was no longer threatening the orbiting lab, and NASA could focus entirely on the delivery mission.

NASA is counting on private business to restock the space station, now that the shuttles have retired to museums.

This newest Dragon will carry up about 1,000 pounds of food, clothes, experiments and equipment. The three space station residents will get a frozen treat when the capsule arrives later in the week: chocolate vanilla swirl ice cream.

Even more cargo will come back when the Dragon parachutes into the Pacific at the end of October.

None of the Russian, European or Japanese cargo ships can bring anything back; they're destroyed during re-entry.

Space Exploration Technologies Corp., or SpaceX -- owned by PayPal co-founder Elon Musk -- is working to convert its unmanned Dragon capsules into vessels that could carry astronauts to the space station in three years. Other U.S. companies also are vying to carry crews. Americans must ride Russian rockets to orbit in the meantime, for a steep price.

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SpaceX to launch cargo ship for space station delivery

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Private Space Station Launches Capsule Sunday

Posted: at 10:20 pm

CAPE CANAVERAL, Fla. (AP) A private company is on the verge of launching another cargo ship to the International Space Station.

On Sunday night, California-based SpaceX will attempt to send a Dragon capsule to the orbiting lab and its three-member crew.

Liftoff of the company's unmanned Falcon rocket is scheduled for 8:35 p.m. EDT. Forecasters put the odds of acceptable weather at 60 percent. Thick clouds and rain are the main concerns.

A Dragon cargo ship successfully docked to the space station last May, but that was considered a test flight. The coming mission is the first under a $1.6 billion contract with NASA that calls for a dozen resupply flights by SpaceX, essential in the post-shuttle era.

"We got there once. We demonstrated we could do it, so there might be a teeny, teeny bit of relaxation. Not a lot, though," SpaceX President Gwynne Shotwell told reporters Saturday night.

NASA was monitoring a potentially threatening piece of orbiting junk, but said that even if the space station had to steer clear of the object, that would not delay the SpaceX mission.

This newest Dragon will haul about 1,000 pounds of food, clothes and gear, including ice cream for the American, Russian and Japanese astronauts on board. (The ice cream will go up in freezers meant for research). Even more cargo will be coming back.

The capsule will remain docked to the space station for most of October. Astronauts will fill the capsule with blood and urine samples, other experiments and old equipment, for its return to Earth at the end of the month. By then, the complex will be back to a full crew of six.

The nearly 500 tubes of blood and syringes of urine have been stashed in space station freezers since the last space shuttle flight, by Atlantis, in July 2011. The decommissioned Atlantis, and sister ships Discovery and Endeavour, are now museum relics.

NASA nutritionist Scott Smith said these blood and urine samples part of medical studies will be the first to be returned since Atlantis' final voyage.

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