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Category Archives: Transhuman News

New insights into virus proteome: Unknown proteins of the herpesvirus discovered

Posted: November 24, 2012 at 7:43 pm

ScienceDaily (Nov. 23, 2012) The genome encodes the complete information needed by an organism, including that required for protein production. Viruses, which are up to a thousand times smaller than human cells, have considerably smaller genomes. Using a type of herpesvirus as a model system, the scientists of the Max Planck Institute (MPI) of Biochemistry in Martinsried near Munich and their collaboration partners at the University of California in San Francisco have shown that the genome of this virus contains much more information than previously assumed.

The researchers identified several hundred novel proteins, many of which were surprisingly small. The results of the study have now been published in Science.

More than 80 percent of the world's population is infected with the herpesvirus, which can cause severe diseases in newborns and in persons with weakened immune system. Researchers had already sequenced the herpesvirus genome 20 years ago, thinking they could then predict all proteins that the virus produces (virus proteome). Now scientists from the research department of Matthias Mann, director at the MPI of Biochemistry, and their American colleagues have analyzed the information content of the genome more precisely.

Small but highly complex

To carry out their study, the scientists infected cells with herpesvirus and observed which proteins the virus produced inside the cell over a period of 72 hours. In order for proteins to be produced at all, the cell machinery must first make copies of the genetic material as intermediate products (RNA). While investigating the intermediate products of the herpesvirus, the American collaborators discovered many novel RNA molecules which were in large part surprisingly short.

They also found that the organization of information required for protein production in the virus genome was far more complex than previously assumed. Annette Michalski, a scientist in the Department of Proteomics and Signal Transduction at the MPI of Biochemistry, was subsequently able to confirm directly the predicted viral proteins in the infected cell using mass spectrometry. This method enables an overview of the complete proteome of the virus-infected cell.

The results of the American and German researchers provide detailed insight into the complex mechanisms used by the virus. "We showed that it's not enough merely to know the virus genome to understand the biology of the herpesvirus," Annette Michalski said. "What is important is to look at the products actually produced from the genome." Even human genes may be much more complex than the genome sequence itself indicates, commented the researchers. Matthias Mann and his colleagues plan to investigate this question further in the coming years.

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New insights into virus proteome: Unknown proteins of the herpesvirus discovered

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Daniel Ryan on the role of the insurance industry funding longer lives – Video

Posted: at 7:42 pm


Daniel Ryan on the role of the insurance industry funding longer lives
Daniel Ryan, Head Life Health R D, Swiss Re In an interview with Daniel Ryan he provides answers to the following questions: What are your key takeaways from this conference? How will the points you #39;ve just mentioned impact future life expectancy? What is the role of the insurance industry in managing longevity risk? Daniel Ryan spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his panel discussion is available at cgd.swissre.comFrom:swissretvViews:8 1ratingsTime:02:55More inScience Technology

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Helen Chung on health policy and longer lives – Video

Posted: at 7:42 pm


Helen Chung on health policy and longer lives
Helen Chung, Head of Health Policy Research, Life Health R D, Swiss Re In an interview with Helen Chung she provides answers to the following questions: What were the thoughts behind the themes addressed at the conference? In what ways can health policy help us life longer lives? What are your key takeaways from the conference? Helen Chung spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of her panel discussion is available at cgd.swissre.comFrom:swissretvViews:5 1ratingsTime:04:28More inScience Technology

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Helen Chung on health policy and longer lives - Video

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Omid Farokhzad on transforming drug delivery through nano-medicine – Video

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Omid Farokhzad on transforming drug delivery through nano-medicine
Omid Farokhzad, Associate Professor, Brigham and Women #39;s Hospital, Harvard Medical School In an interview with Omid Farokhzad he provides answers to the following questions: What are the key messages of your workshop? How do you see the future of nanomedicine develop and how might this impact the future of longevity? What did you learn at the conference and how did it inspire you? Farokhzad spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his keynote is available at cgd.swissre.comFrom:swissretvViews:2 1ratingsTime:03:41More inScience Technology

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Omid Farokhzad on transforming drug delivery through nano-medicine - Video

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Elias Mossialos on health policy and innovating for longevity – Video

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Elias Mossialos on health policy and innovating for longevity
Elias Mossialos, Brian Abel-Smith Professor of Health Policy, London School of Economics In an interview with Elias Mossialos he provides answers to the following questions: What are the key messages of your presentation? How do you see the future of health systems and policy, and how might this impact the future of longevity? What did you learn at the conference and how did it inspire you? Elias Mossialos spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his keynote is available at cgd.swissre.comFrom:swissretvViews:4 1ratingsTime:03:09More inScience Technology

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Elias Mossialos on health policy and innovating for longevity - Video

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James Heywood on what is health and how we can learn what it means – Video

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James Heywood on what is health and how we can learn what it means
James Heywood, Co-Founder and Chairman, PatientsLikeMe In an interview with James Heywood he provides answers to the following questions: What are the key messages of your presentation? How do you see the future of online self-reported patient data collection and how might this impact the future of longevity? What did you learn at the conference and how did it inspire you? James Heywood spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his keynote is available at cgd.swissre.comFrom:swissretvViews:3 1ratingsTime:03:01More inScience Technology

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James Heywood on what is health and how we can learn what it means - Video

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Nick Wood on translating genetics into neurological disease and management – Video

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Nick Wood on translating genetics into neurological disease and management
Nick Wood, Professor in Clinical Neurology and Neurogenetics, University of London, Director Institute of Human Genetics and Health In an interview with Nick Wood he provides answers to the following questions: What are the key messages of your presentation? How do you see the future of treatment of neurological diseases develop and how might this impact the future of longevity? What did you learn at the conference and how did it inspire you? Nick Wood spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his keynote is available at cgd.swissre.comFrom:swissretvViews:2 1ratingsTime:01:39More inScience Technology

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Nick Wood on translating genetics into neurological disease and management - Video

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Experts on key drivers of human longevity – Video

Posted: at 7:42 pm


Experts on key drivers of human longevity
The following experts provide their views on what they think are the key drivers for future human longevity: - Helen Chung, Head of Health Policy Research, Life Health R D, Swiss Re - James Heywood, Co-Founder and Chairman, PatientsLikeMe - Elias Mossialos, Brian Abel-Smith Professor of Health Policy, London School of Economics - Nick Wood, Professor in Clinical Neurology and Neurogenetics, University of London, Director Institute of Human Genetics and Health - Omid Farokhzad, Associate Professor, Brigham and Women #39;s Hospital, Harvard Medical School - Daniel Ryan, Head Life Health R D, Swiss Re The experts spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.comFrom:swissretvViews:12 1ratingsTime:03:48More inScience Technology

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Experts on key drivers of human longevity - Video

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Bern Shen on how technology reduces some risk and increases others – Video

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Bern Shen on how technology reduces some risk and increases others
Bern Shen, Chief Medical Officer, HealthCrowd In an interview with Bern Shen he provides answers to the following questions: What are the key messages of your workshop? How do you see the future of health-related technologies develop and how might they impact the future of longevity? What did you learn at the conference and how did it inspire you? Bern Shen spoke at the Swiss Re conference The future of human longevity: focusing on you cgd.swissre.com A recording of his keynote is available at cgd.swissre.comFrom:swissretvViews:1 1ratingsTime:01:43More inScience Technology

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November Baby, Thanksgiving OOTD, and 100% Pure Cosmetics Giveaway Contest! – Video

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November Baby, Thanksgiving OOTD, and 100% Pure Cosmetics Giveaway Contest!
Happy Thanksgiving! Since tis the season of thanks and giving, thought it would be the opportune time to do a giveaway! This giveaway features products from 100% Pure Cosmetics, one of the top eco-beauty brands in the Bay Area of California, USA. They started out in the Eastbay and have now expanded into the Southbay. Their ingredients are certified organic by the USDA and personally have been using them for years without any issues of it triggering my eczema or breakouts. In fact, I would dare to say their products do the opposite and help heal and fortify skin. It #39;s never been better. So to enter this contest, you just need to do 2 things: 1. Subscribe to my Youtube channel 2. Comment below on your favorite eco-friendly/green beauty brand/product. Or tell me about a product you have trouble finding for your skincare or makeup routine that you would like to find out about. I #39;ve been my own guinea pig for as long as I can remember, so I #39;ve tried as many products that say they are "hypoallergenic" as possible (as well as keep searching for new and upcoming brands) and can probably direct you to a brand or two to help with your needs. Also, I wrote a blog for Thanksgiving on what I #39;m thankful for this year. It also lists a number of other eco-beauty brands that are hypoallergenic and that I #39;ve personally tested to verify this. You can read it here (it also has lots of pictures :)): terryalabata.wordpress.com I also included my OOTD for fun. Love dressing up! Currently ...From:TerryAlabataViews:32 1ratingsTime:06:52More inHowto Style

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November Baby, Thanksgiving OOTD, and 100% Pure Cosmetics Giveaway Contest! - Video

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