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Category Archives: Transhuman News

DNA sleuth hunts wine roots in Anatolia

Posted: November 28, 2012 at 5:44 pm

There are easier places to make wine than the spectacular, desolate landscapes of southeast Turkey, but DNA analysis suggests it is here that Stone Age farmers first domesticated the wine grape.

Today Turkey is home to archaeological sites as well as vineyards of ancient grape varieties like Bogazkere and Okuzgozu, which drew the curiosity of the Swiss botanist and grape DNA sleuth Jose Vouillamoz, for the clues they may offer to the origin of European wine.

Together with the biomolecular archaeologist Patrick McGovern, Vouillamoz has spent nearly a decade studying the world's cultivated and wild vines.

"We wanted to collect samples from wild and cultivated grape vines from the Near East -- that means southeastern Anatolia, Armenia and Georgia -- to see in which place the wild grape was, genetically speaking, linked the closest to the cultivated variety."

"It turned out to be southeastern Anatolia," the Asian part of modern Turkey, said Vouillamoz, speaking at the EWBC wine conference in the Turkish city of Izmir this month. "We propose the hypothesis that it is most likely the first place of grape vine domestication."

McGovern's lab at the University of Pennsylvania Museum also provided archaeological evidence of wine's Anatolian roots after analysing residues of liquid recovered from vessels thousands of years old.

Author of "Uncorking the Past" and "Ancient Wine", McGovern used a sensitive chemical technique to look for significant amounts of tartaric acid -- for which grapes are the only source in the Middle East.

While Georgia, Armenia and Iran all played a role in ancient winemaking, preliminary evidence from pottery and even older clay mineral containers, seems to place the very first domestication of the wild Eurasian grape Vitis vinifera in southeastern Anatolia sometime between 5,000 and 8,500 BC, McGovern said.

Southeast Anatolia is part of the Fertile Crescent, the name given to a vast area stretching through modern-day Iraq and Iran to the Nile Valley in the south, widely seen as the birthplace of the eight so-called "founder" crops -- from chickpea to barley -- that are the world's first known domesticated plants.

Evidence found by the research duo suggests that for wine too, hundreds of today's grapes find their roots in "founder" varieties descended from the wild grapes of the region.

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DNA sleuth hunts wine roots in Anatolia

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'Bigfoot' Is Part Human, DNA Study Claims

Posted: at 5:44 pm

Genetic testing confirms the legendary Bigfoot is a human relative that arose some 15,000 years ago at least according to a press release issued by a company called DNA Diagnostics detailing supposed work by a Texas veterinarian.

The release and alleged study by Melba S. Ketchum also suggests such cryptids had sex with modern human females that resulted in hairy hominin hybrids, but the scientific community is dubious about her claim.

"A team of scientists can verify that their five-year long DNA study, currently under peer-review, confirms the existence of a novel hominin hybrid species, commonly called 'Bigfoot' or 'Sasquatch,' living in North America," the release reads. "Researchers' extensive DNA sequencing suggests that the legendary Sasquatch is a human relative that arose approximately 15,000 years ago."

For her study, Ketchum obtained three "whole nuclear genomes from purported Sasquatch samples. The genome sequencing shows that Sasquatch mtDNA is identical to modern Homo sapiens, but Sasquatch nuDNA is a novel, unknown hominin related to Homo sapiens and other primate species." (Mitochondrial DNA, or mtDNA, is the DNA that resides in the cell's energy-producing structures, and is typically passed down from mothers, while nuclear DNA, nuDNA, resides in the cells' nuclei and is passed down from both parents to offspring.)

"Our data indicate that the North American Sasquatch is a hybrid species, the result of males of an unknown hominin species crossing with female Homo sapiens," the statement reads. [Infographic: Tracking Belief in Bigfoot]

Any proof?

It's a fascinating theory.

So where's the evidence? Well, there is none. Not yet, anyway: Ketchum's research has not appeared in any peer-reviewed scientific journal, and there's no indication when that might happen. If the data are good and the science is sound, any reputable science journal would jump at the chance to be the first to publish this groundbreaking information. Until then, Ketchum has refused to let anyone else see her evidence.

Of course the history of Bigfoot is rife with exaggerated and premature claims about proof of the creature's existence. For decades, various types of evidence have been offered as final, definitive proof, ranging from Bigfoot hair to blood to dead bodies. Without exception, the evidence has always been hoaxed, misidentification or inconclusive.

Because Ketchum has released no information at all about her findings (nor have they been examined by outside experts), it's impossible to evaluate the validity of her conclusions. But an important clue can be found in her statement that "Sasquatch mtDNA is identical to modern Homo sapiens."

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'Bigfoot' Is Part Human, DNA Study Claims

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Scientist claims to have sequenced ‘Bigfoot’ DNA

Posted: at 5:44 pm

A frame from the October 20th, 1967 Patterson-Gimlin film claiming to depict BigfootA Texas scientist claims to have sequenced the DNA of Sasquatch, a creature whose very existence is mysterious to many and purely mythological to most.

"Our study has sequenced 20 whole mitochondrial genomes and utilized next generation sequencing to obtain 3 whole nuclear genomes from purported Sasquatch samples," Dr. Melba S. Ketchum of Nacogdoches, Texas, says in a news release.

"The genome sequencing shows that Sasquatch mtDNA is identical to modern Homo sapiens, but Sasquatch nuDNA is a novel, unknown hominin related to Homo sapiens and other primate species."

Ketchum writes that her team's research indicates the "North American Sasquatch" is a hybrid of a female Homo sapien and a male of "unknown hominin species," whose DNA matched approximately 15,000 years ago.

Sasquatch, more commonly known as Bigfoot, has been a staple of American mythology for hundreds of years. The modern Sasquatch theories took on a newfound prominence in 1958 when the first official Bigfoot search party was launched in California.

Most members of the scientific community have discounted the Sasquatch theory. However, in a Sept. 27, 2002, interview with National Public Radio, Jane Goodall appeared open to the concept, saying, "Maybe they don't exist, but I want them to."

So, how do Ketchum's claims hold up under scrutiny?

The Houston Chronicle's Eric Berger does some unraveling of Ketchum and the claims she made in the news release.

For starters, Berger notes that while Ketchum has 27 years of genetic research experience during her career as a veterinarian, her company, DNA Diagnostics, has received an "F" rating from the Better Business Bureau.

But more important, Ketchum has not allowed scientific peer review of her findings.

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Scientist claims to have sequenced ‘Bigfoot’ DNA

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Dr Bartha Knoppers on the Power of Genomics – Video

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Dr Bartha Knoppers on the Power of Genomics
As part of the Genome Canada / Gairdner Foundation Genomics: The Power and the Promise conference being held in Ottawa, we shot some quick videos of various people across Canada talking about the potential power of genomics. The Power and Promise conference and gala dinner brings together some of the top experts in the field of genomics and examines the impact of genomics on Canada #39;s bioeconomy, health, agriculture, and the environment.From:OntarioGenomicsClipsViews:0 0ratingsTime:01:15More inScience Technology

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Dr Bartha Knoppers on the Power of Genomics - Video

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R7 representation of uncontrolled Connectrons – Video

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R7 representation of uncontrolled Connectrons
A graphic showing where the sources of the uncontrolled Connectrons occur in all the chromosomes of the mouse genome.From:Richard J. FeldmannViews:2 0ratingsTime:02:46More inScience Technology

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R7 representation of uncontrolled Connectrons - Video

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R4 representation of Connectrons – Video

Posted: at 5:44 pm


R4 representation of Connectrons
A graphic showing how sources on other chromosomes determine Connectrons on chromosome 1 of the mouse genome.From:Richard J. FeldmannViews:0 0ratingsTime:06:01More inScience Technology

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R4 representation of Connectrons - Video

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Yeast Nuclear Structure – Video

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Yeast Nuclear Structure
Shows the nuclear structure of the yeast genomeFrom:Richard J. FeldmannViews:1 0ratingsTime:09:34More inScience Technology

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Yeast Nuclear Structure - Video

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Simplified Access and Mining of The Cancer Genome Atlas (TCGA) Copy Number Data – Video

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Simplified Access and Mining of The Cancer Genome Atlas (TCGA) Copy Number Data
The Cancer Genome Atlas (TCGA) has generated a wealth of genomic information for a wide range of cancers. Much of the data is available publicly on the internet via the TCGA portal. Although the data portal provides access to download processed data as well as the ability to issue simple queries, the utility of this tool is rather limited for most research applications. BioDiscovery has solved these issues by 1) downloading the publically available (Level 3) data and associated phenotypic data onto a single, secure, cloud-based repository-Nexus DB 2) providing free and easy access to this data to Nexus Copy Number users and 3) providing user-friendly tools (Nexus Copy Number and Nexus DB) to analyze and mine this data. In this presentation we will show how to search and query this data with Nexus Copy Number and Nexus DB to find, for example, projects with a particular aberration signature or projects with specific affected genes. We will also discuss possible issues with the level 3 data and how the raw data can be used to obtain a more accurate representation of the data.From:BioDiscoveryIncViews:0 0ratingsTime:48:13More inScience Technology

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Simplified Access and Mining of The Cancer Genome Atlas (TCGA) Copy Number Data - Video

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Klick Health Trashes the Company FAQ in Favor of Video Q

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Klick Health Trashes the Company FAQ in Favor of Video Q A
At the E2 Innovate conference in Santa Clara, California, the trade show floor was lined with different companies trying to sell their all-in-one enterprise collaboration solution. Klick Health could have chosen that path, but instead spent the last ten years developing its own internal collaboration system called Genome, explained Jay Goldman, SVP Innovation for Klick Health. Genome started on this belief that email sucks and it #39;s a horrible tool to use to track any tasks that need to be completed, said Goldman. With the introduction of Genome, Klick Health banned email internally and stopped using it for tracking any tasks. Today, it #39;s a single system that runs the whole company. It has become their travel system, their expense system, budgeting, finances, project management, and everything else that has to do with the business happens through Genome, said Goldman. KlickTalk -- Video Q A among employees One element of Klick Health #39;s Genome is KlickTalk, a resource pool comprised of video answers coworkers have about common office questions. They could be internal questions such as "How do I do an expense report?" or "How do I set up my vacation days?" Or they can be client related such as "Who do I get in touch with for this issue?" The purpose of KlickTalk, explained Goldman is "we don #39;t want people to get hung up on those questions because they can become big time sucks. Or people put off something to do because they don #39;t know how to do it." Ask the question to the ...From:kigniteViews:0 0ratingsTime:04:04More inPeople Blogs

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Klick Health Trashes the Company FAQ in Favor of Video Q

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Watch Horizon: Miracle Cure? A Decade of the Human Genome Online Full Movie – Video

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Watch Horizon: Miracle Cure? A Decade of the Human Genome Online Full Movie
Full Movie Link: http://www.zexnetworks.comFrom:Tommie SeeleyViews:0 0ratingsTime:00:36More inFilm Animation

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Watch Horizon: Miracle Cure? A Decade of the Human Genome Online Full Movie - Video

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