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Category Archives: Transhuman News

World's 'oldest person' dies at 132

Posted: October 10, 2012 at 3:11 am

London, Oct 8 (IANS) A Georgian woman who claimed to be 132-years-old - making her the world's oldest human being ever - has died, The Independent reported Monday.

Antisa Khvichava claimed to have been born July 8, 1880, and had a Soviet-era passport and documentation to that effect, but her age was contested and never officially proven.

She lived in Sachino village in northwest Georgia with her 42-year-old grandson and claimed to have retired from her job as a tea and corn picker in 1965, when she was 85.

Khvichava claimed to be just 10-years younger than Russia's first communist leader Vladimir Lenin and to have been born a year before the death of celebrated Russian writer Fyodor Dostoyevsky.

She said she had 12 grandchildren, 18 great-grandchildren and four great-great-grandchildren and reportedly attributed her longevity and good health to drinking a small amount of local brandy every day, according to the newspaper.

Her original birth certificate is said to have been lost during the years of revolutions and civil wars that ravaged Georgia following the fall of the USSR.

But local officials, friends, neighbours and descendants have all back up the claim she was 132 when she died, the daily said.

The oldest living person at the moment is 116-year-old Besse Cooper from the state of Georgia in the US. Her birth can be officially proven to have been in August 1896.

The oldest ever verified person was French woman Jeanne Calment, born in February 1875, who lived to 122 years and 164 days before dying in August 1997.

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World's 'oldest person' dies at 132

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How Did Woman Live to 132?

Posted: at 3:11 am

Possibly the last person on the planet who knew the taste of the air in 1880 has died.

Antisa Khvichava, who claimed to be 132 years old, was enjoying her 47th year of retirement in Sachino, a remote village in the former Soviet republic of Georgia, when she passed away, according to a British newspaper, the Independent. If she was as old as she said, Khvichava would've been the oldest person to ever live.

Though a birth certificate and passport indicate Khvichava was born July 8, 1880, they are replacements of documents she had lost over the years, raising skepticism over her claim.

But science can't rule out her feat absolutely. If there's a maximum possible human age, it hasn't been found yet.

In 1798, the then-oldest verified person died at 103, according to the Gerontology Research Group. In 1997, France's Jeanne Calment, the current verified oldest, died at 122. [Infographic: Global Life Expectancy]

If Kvichava did, indeed, walk the Earth for well over a century, what did she do right?

Based on current science, the answer might be that, other than avoiding obvious physical threats, she didn't do much to earn her longevity.

Researchers at the Albert Einstein College of Medicine of Yeshiva University showed last year that, among a studied population of people older than 95, bad health habits such as smoking, drinking, poor diet and lack of exercise were about as common as in the general population, meaning their longevity seemed to be largely based on genes.

But this does not mean the general population should abandon healthy living and adopt a doctrine of genetic fatalism. Rather, that study and others suggest longevity outliers like Kvichava, a reported daily brandy drinker, have rare genetic protections that transcend unhealthy habits, propelling them into very old age in spite of lifestyle.

For people who aren't prepared to take a gamble that they're genetically predisposed to break 100 (the 2010 Census counted 53,364 centenarians in the United States), the famously abstemious and healthy-living Seventh-Day Adventists seem to hint at a practical regimen for increasing lifespan.

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How Did Woman Live to 132?

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Now available: Naturally sourced eczema treatment for babies

Posted: at 3:11 am

Mustela Philippines distributor Sharleen Cu-unjieng with Metro magazines Charmagne Laconico

Mention the name Mustela to any mother and her eyes light up. This is immediately followed by oh I looove that!

The brand was brought to the Philippines by moms Tammy Tancinco and Sharleen Cu-Unjieng after they discovered Mustelas wonders.

So legendary was Mustelas reputation that it was actually Sharleens yaya who recommended Mustela to relieve her babys diaper rash.

Mustela is the No. 1-selling mom-and-baby product in European pharmacies. It is manufactured by Laboratoires Expanscience, which is the sixth largest independent laboratory in France, which ensures its products are free from paraben, phthalate, phenoxyethanol, alcohol, chlorphenesin and oils. The firm uses ingredients of natural origins.

Stylish moms headed by chef Francesca Cario gathered at the newly opened Premio restaurant at The Fort for the launch of Mustelas Stelatopia line for babies with atopic or eczema-prone skin.

HOST Lexi Schulze

My own two children suffer from eczema-prone skin and so I was interested to try out a new product that would replace the use of steroid creams.

When my son was small I vowed not to use strong medicines on him. However, his eczema flare-ups would get so bad that I was forced to use steroids to relieve the itching and redness that would sometimes disrupt his sleep.

JACKIE Antonio, Juana Yupangco

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Now available: Naturally sourced eczema treatment for babies

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Interim Analysis Supports Continuation of Can-Fite's Phase 2/3 Psoriasis Clinical Study with CF101

Posted: at 3:11 am

PETAH TIKVA, Israel, Oct. 9, 2012 /PRNewswire/ --Can-Fite BioPharma (TASE: CFBI; OTC: CANFY) announced today the continuation of patient enrollment in its Psoriasis Phase 2/3 clinical study with CF101. This decision follows an interim analysis of safety and efficacy data from the first 103 patients who completed 24 weeks of treatment in the trial. The positive clinical effects of the CF101-2 mg BID dose relative to placebo were observed in a variety of standard psoriasis assessment parameters, with the responses accumulating steadily over the 24-week treatment period. These clinical effect data corroborate the published Phase 2 study and confirm the dose selection, while the favorable safety profile of CF101 further supports its development for the systemic treatment of moderate-to-severe psoriasis. To allow the trial to meet its full objectives, the company therefore intends to complete patient enrollment for this Psoriasis Phase 2/3 clinical study comparing CF101-2 mg BID to placebo, as standalone therapy. The study will include approximately 300 patients overall and is currently conducted in 17 U.S., European and Israeli medical centers.

Psoriasis is a skin condition that affects 2% to 3% of the general population. The psoriasis therapeutic market is estimated at $3.5 billion annually and is dominated by biological drugs.

Can-Fite CEO Pnina Fishman, Ph.D., commented, "We are pleased to continue the clinical development plan of CF101, a small molecule orally bioavailable drug, based on its encouraging therapeutic index. CF101's anti-inflammatory effect, its well-defined mechanism of action, and the excellent safety profile, all suggest this drug is an attractive candidate for the treatment of psoriasis."

The company also announced that it has listed and begun trading of its American Depository Receipts (ADRs). Shares of the ADRs launched on October 2nd, 2012 on the over-the-counter (OTC) market under the symbol CANFY. The Company's ordinary shares trade on the Tel Aviv Stock Exchange under the symbol CFBI and each ADR share represents 50 ordinary shares.

About CF101

CF101, an A3 adenosine receptor agonist, is a novel, first in class, small molecule, orally bioavailable drug with a favorable therapeutic index demonstrated in Phase 2 clinical studies. CF101 is currently developed for the treatment of autoimmune inflammatory diseases including rheumatoid arthritis (Phase 2b) and psoriasis (Phase 2/3). CF101 is also developed for ophthalmic indications including dry eye syndrome (Phase 3), glaucoma (Phase 2) and Uveitis by OphthaliX (OPLI), a subsidiary of Can-Fite.

About Can-Fite BioPharma Ltd.

Can-Fite BioPharma Ltd is an Israeli public company, the ordinary shares of which are traded on the Tel Aviv Stock Exchange (CFBI.TA). American Depository Receipts of the company are traded on the over-the-counter market (CANFY). The company, which commenced business activity in 2000, was founded by Pnina Fishman, Ph.D., researcher in the Rabin Medical Center, and Ilan Cohn Ph.D., patent attorney and senior partner at Reinhold Cohn Patent Attorneys. Pnina Fishman serves as CEO of the company. The company was founded on the basis of Fishman's scientific findings, and is focused on the development of small molecule orally bioavailable drugs, ligands to the A3 adenosine receptor. The latter mediates anti-inflammatory and anti-cancer effects and is suggested as a biological predictive marker. The company's lead drug, CF101, is in clinical development for the treatment of autoimmune inflammatory diseases. The CF102 drug candidate is being developed for the treatment of liver diseases. Can-Fite has a wealth of clinical experience: to date, more than 700 patients have participated in clinical trials conducted by the company. Can-Fite previously licensed its activity in the ophthalmic field to OphthaliX Inc., in which it holds a controlling interest (OPLI).

Contact:

KCSA Strategic Communications Jeff Corbin / Phil Carlson jcorbin@kcsa.com/ pcarlson@kcsa.com 212-896-1233

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Interim Analysis Supports Continuation of Can-Fite's Phase 2/3 Psoriasis Clinical Study with CF101

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Rare Gene Deletion Tied To Psychiatric Disease And Obesity

Posted: at 3:11 am

Featured Article Academic Journal Main Category: Psychology / Psychiatry Also Included In: Obesity / Weight Loss / Fitness;Anxiety / Stress;Genetics Article Date: 09 Oct 2012 - 14:00 PDT

Current ratings for: Rare Gene Deletion Tied To Psychiatric Disease And Obesity

5 (1 votes)

In their paper, Carl Ernst, a professor in the Department of Psychiatry at the Faculty of Medicine of McGill University in Montreal, Quebec, Canada, and colleagues, suggest deletion of BDNF, a nervous system growth factor that is important for brain development, leads to major depression, anxiety and obesity.

They are confident they have found a molecular pathway that plays a key role in psychopathology.

Ernst, who is also a researcher at the Douglas Mental Health University Institute (affiliated to McGill), says scientists have been scouring the genome to find regions in our DNA that may tell us something about the genetic origins of psychiatric disorders.

For some time, thanks to animal studies, it has been proposed that BDNF plays several roles in the brain, but no study has yet shown what happens when it is missing from the genome.

In this study, the participants were 35,000 people referred for genetic screening, and over 30,000 controls, in Canada, Europe and the US.

From the genetic screening, five people (including three children) tested positive for BDNF deletions. All five were obese and had mild to moderate intellectual impairment, plus a mood disorder, which in the children comprised anxiety disorder, aggressive disorder, or attention deficit-hyperactivity disorder (ADHD), and in the older subjects comprised anxiety or major depressive disorder.

As they got older, these subject gradually put on weight, which the researchers suggest means obesity happens slowly when it is due to BDNF deletion.

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Rare Gene Deletion Tied To Psychiatric Disease And Obesity

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Dem PAC uses ‘loud’ Joe Walsh in 10th District ads

Posted: at 3:11 am

By Natasha Korecki nkorecki@suntimes.com October 9, 2012 6:38PM

Joe Walsh

storyidforme: 38239911 tmspicid: 12114272 fileheaderid: 5533808

A pro-Democratic group is using video cuts of the loud, politically incorrect Tea Partier Joe Walsh to turn up the volume against Republicans in three key Chicago-area races, including the 10th Congressional District.

Walshs bluster is the centerpiece of a new spot, which is part of a $2.4 million ad buy attacking the congressman, and two other Republicans U.S. Reps. Robert Dold in the 10th District and Judy Biggert in the 11th who are targeted by Democrats.

Dont blame banks! I am tired of hearing that crap! Walsh is seen imploring on a video of him talking to district residents.

In another clip hes shown saying: I want America to pay for my contraceptives. Youre kidding me. Go get a job!

Clearly viewing Illinois as fertile ground to win over congressional seats, the House Majority PAC, which aims to put Democrats back into the lead in Washington, on Tuesday disclosed it had pumped $2.4 million into the three key Chicago-area races including U.S. House races in the 6th, 10th and 11th congressional districts.

One video, entitled Loud links Walsh to Dold and Judy Biggert, both of whom are incumbents. While Walsh is a Tea Partier through and through, both Dold and Biggert are far more moderate.

Still, the ad, which, according to the House Majority PAC, will run in heavy rotation for two weeks, works to link the three as equally out of step but only plays video snippets of Walsh talking.

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Dem PAC uses ‘loud’ Joe Walsh in 10th District ads

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Democratic PAC uses ‘loud’ Walsh in ads against other Dold, Biggert

Posted: at 3:11 am

By Natasha Korecki Sun-Times Media October 9, 2012 4:14PM

Updated: October 9, 2012 5:58PM

A pro-Democratic group is using video cuts of the loud, politically incorrect tea partyer Joe Walsh to turn up the volume against Republicans in three key Chicago-area races.

Walshs bluster is the centerpiece of a new spot, which is part of a $2.4 million ad buy attacking the 8th District congressman from McHenry, and two other Republicans who are targeted by Democrats.

Dont blame banks! I am tired of hearing that crap! Walsh is seen imploring on a video of him talking to district residents.

In another clip hes shown saying: I want America to pay for my contraceptives. Youre kidding me. Go get a job!

Clearly viewing Illinois as fertile ground to win over congressional seats, the House Majority PAC, which aims to put Democrats back into the lead in Washington, disclosed Tuesday it had pumped $2.4 million into the three key Chicago-area races including U.S. House races in the 8th, 10th and 11th congressional districts.

One video titled Loud links Walsh to U.S. Reps. Bob Dold of Kennilworth and Judy Biggert of Hinsdale, both of whom are incumbents. While Walsh is a tea partyer through and through, both Dold and Biggert are far more moderate. Still, the ad which, according to the House Majority PAC, will run in heavy rotation for two weeks works to link the three as equally out of step but only plays video snippets of Walsh talking.

Incidentally, the cut of Walsh saying Go Get a Job cut off the second part of his quote. The full quote from that day was Go Get a Job, Sandra Fluke. Fluke is the woman who testified before Congress about affordable birth control, only to be berated by conservative talk-show host Rush Limbaugh as a slut.

The HousePAC is banking on Walsh being so unpopular in Illinois that he will help sink two other Republican incumbents.

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Democratic PAC uses ‘loud’ Walsh in ads against other Dold, Biggert

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Democratic PAC uses ‘loud’ Joe Walsh in ads against Dold, Biggert

Posted: at 3:11 am

By Natasha Korecki Political Reporter/@natashakorecki October 9, 2012 9:04AM

Updated: October 9, 2012 10:10PM

A pro-Democratic group is using video cuts of the loud, politically incorrect Tea Partier Joe Walsh to turn up the volume against him and two other Republicans in three key Chicago-area races.

Dont blame banks! I am tired of hearing that crap! Walsh is seen imploring on a video of him talking to 8th Congressional District residents.

In another clip hes shown saying: I want America to pay for my contraceptives. Youre kidding me. Go get a job!

Clearly viewing Illinois as fertile ground to win over congressional seats, the House Majority PAC, which aims to put Democrats back into the lead in Washington, on Tuesday disclosed it had pumped $2.4 million into the three U.S. House races in the 8th, 10th and 11th congressional districts.

One video, entitled Loud links Walsh to U.S. Representatives Bob Dold and Judy Biggert. While Walsh is a Tea Partier through and through, both Dold and Biggert are far more moderate. Still, the ad, which, according to the House Majority PAC, will run in heavy rotation for two weeks, on both cable and broadcast, works to link the three as equally out of step even thought it only plays video snippets of Walsh talking.

Incidentally, the cut of Walsh saying Go Get a Job, was only a partial quote. The full quote from that day was Go Get a Job, Sandra Fluke.

Fluke is the woman who testified before Congress about affordable birth control, only to be berated by conservative talk-show host Rush Limbaugh as a slut.

The HousePAC is banking on Walsh being so unpopular in Illinois, he will help sink two other Republican incumbents.

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Democratic PAC uses ‘loud’ Joe Walsh in ads against Dold, Biggert

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Iran censors currency rates as rial suffers

Posted: at 3:11 am

Iran on Tuesday stepped up censorship of websites that usually give foreign currency rates for its pummelled money, the rial, as the exchange market remained virtually paralysed and under tight scrutiny.

Sites such as Mesghal.com and Mazanex.com had rates blanked out for the rial's value against many other nations' currencies, extending a censorship that previously applied to dollar and euro rates.

The market rate for gold coins was also missing.

In Tehran's money changing district, licensed bureaux were doing no business at the rate of 28,500 rials to the dollar imposed since Saturday by the central bank in an effort to reverse a collapse of the money last week.

Instead, a few black market dealers were offering the dollar at 35,000 rials -- close to the all-time low of more than 36,000 reached last week when the rial plunged 40 percent in value.

Iran's currency market has effectively been frozen since October 3, when protests erupted in central Tehran over the sliding rial.

Although shopkeepers and exchange bureaux have since reopened, they are doing little trade.

Merchants in the city's historic Grand Bazaar, which packs political weight in Iran, have greatly increased prices, to the dismay of shoppers. Several were refusing to sell goods until the currency situation stabilises.

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Iran censors currency rates as rial suffers

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Ron Paul to Appear in New Film About U.S. Economy

Posted: at 3:10 am

In The Bubble, Paul criticizes the Federal Reserve and says America is facing an inflationary depression.

New York, NY (PRWEB) October 09, 2012

In the film, Paul says that Ben Bernanke's response to the 2008 crisis is only postponing America's fiscal problems. Paul believes that the massive increase in the money supply by the Fed will lead to extreme inflation and terrible unemployment. He says it is absolutely delusional to think we are entering into a period of recovery with either Romney or Obama. The Congressman was quick to point out that both Republicans and Democrats played a part in passing the recent stimulus acts and bailouts.

The standard of living is going down, Paul stated. The culprit is lower than market interest rates. The keynesians don't emphasize the need for production. They just want to create money and get people in the government to spend money...it is a very corrupt system and it is very unworkable.

The raw footage of Ron Paul and the rest of the cast member interviews are available online at http://www.TheBubbleFilm.com. Updates about the film, including information about its upcoming 2012 release, can also be found at http://www.Facebook.com/TheBubbleFilm.

Tyler Whitney The Bubble (517) 420-3186 Email Information

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