Category Archives: Genetic Engineering

PUBLIC RELEASE DATE:

15-Dec-2014

Contact: Kathryn Ryan kryan@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News @LiebertOnline

New Rochelle, NY, December 15, 2014-Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Genetic Testing and Molecular Biomarkers website until January 11, 2014.

Xin Guo, First Affiliated Hospital of Harbin Medical University, China, and Jiaqi Liu, Liuping You, Gang Li, Yuenan Huang, and Yunlong Li, Second Affiliated Hospital of Harbin Medical University, explored the relationship between two polymorphisms in the adiponectin gene and the risk of colorectal cancer in the article "Association Between Adiponectin Polymorphisms and the Risk of Colorectal Cancer." They also showed that these genetic variations may interact with environmental factors, such as red meat intake, to affect cancer risk.

"This paper suggests that adiponectin gene sequence may have significant prognostic value for colorectal cancer," says Kenneth I. Berns, MD, PhD, Editor-in-Chief of Genetic Testing and Molecular Biomarkers, and Director of the University of Florida's Genetics Institute, College of Medicine, Gainesville, FL.

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About the Journal

Genetic Testing and Molecular Biomarkers is an authoritative peer-reviewed journal published monthly online with Open Access options and in print that reports on all aspects of genetic testing, including molecular and biochemical based tests and varied clinical situations; ethical, legal, social, and economic aspects of genetic testing; and issues concerning effective genetic counseling. Genetic Testing and Molecular Biomarkers is the official journal of Genetic Alliance. Complete tables of content and a free sample issue may be viewed on the Genetic Testing and Molecular Biomarkers website.

About the Publisher

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New colorectal cancer risk factor identified

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Genomics researcher Alison Van Eenennaam, with Monsanto's Robert Fraley, argues that genetically modified foods have increased farmers' yields and profits around the world. Samuel LaHoz/Intelligence Squared U.S. hide caption

Genomics researcher Alison Van Eenennaam, with Monsanto's Robert Fraley, argues that genetically modified foods have increased farmers' yields and profits around the world.

Many plants we eat today are a result of genetic modifications that would never occur in nature. Scientists have long been altering the genes of food crops, to boost food production and to make crops more pest-, drought- and cold-resistant.

Proponents of genetically modified organisms, or GMOs, say that farmers who grow these crops are able to use fewer environmentally damaging pesticides. The increased yields of GMO crops, they also argue, are essential to feeding the world's growing population. And proponents say that numerous studies have shown that genetically modified foods are safe to eat.

Critics, however, say the claims of those benefits are overblown. They say farmers growing GMO crops have actually increased their use of herbicides. And widespread use of the crops, they say, have also led to an increase in herbicide- and pesticide-resistant weeds and insects. And, they argue, there is still no scientific consensus on the long-term safety of these foods.

Four scientists recently took on those questions in an Intelligence Squared U.S. debate, facing off two against two on the motion, "Genetically Modify Food." In these Oxford-style debates, the team that sways the most people to its side by the end is the winner.

Before the debate, the audience at the Kaufman Music Center in New York voted 32 percent in favor of the motion, with 30 percent against and 38 percent undecided. Afterward, 60 percent agreed with the motion, and 31 percent disagreed making the side arguing in favor of the motion the winners of this debate.

Those debating:

FOR THE MOTION

Robert Fraley is executive vice president and chief technology officer at Monsanto, where he has worked for more than 30 years. He currently oversees the company's global technology division which includes plant breeding, biotechnology and crop protection research facilities in dozens of countries. Fraley has authored more than 100 publications and patent applications. In 2013, he was honored as a World Food Prize Laureate and is the recipient of numerous awards, including the 2008 National Academy of Sciences Award for the Industrial Application of Science for his work on crop improvement and the National Medal of Technology from President Clinton in 1999.

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