Category Archives: DNA

Ginkgo Bioworks Holdings, (DNA) disclosed a change of 6.58% and its listed share value at $11.17 in the recent trade transaction. This company belong to USA Country and part of Healthcare sector. DNA exchanged 59206633 shares on hands in most recent trading session and observed an average volume with 8406.33K shares. The stock acknowledged active focus on shares in the current trading session. It has a market capitalization of $16309.99M. Using market capitalization to display company size because this is basic factor of different characteristics to develop the investors interests including risk.

TECHNICAL INTERPRETATION:

A Simple moving average is one of the most flexible as well as most-commonly used technical analysis indicators. It is highly popular among traders, mostly because of its simplicity. It works best in a trending environment. Simple Moving Average calculated as an average of the last N-periods (20-Day, 50-Day, 200-Day).The share price is positive from its 20 days moving average with 1.53% and trading from 50 days moving average with -9.08%. The stock price is performing along rising drift from its 200 days moving average with 3.26%.Any type of moving average can be used to generate buy or sell signals and this process is very simple. The charting software plots the moving average as a line directly into the price chart.

Currently Relative Strength Index (RSI-14) reading of stock is 49.55. RSI reading varies between 0 and 100. Speed and change of stock price movement is measured by the RSI momentum oscillator. J. Welles Wilder developed Relative Strength Index (RSI) that is used most commonly as momentum indicator. Commonly when RSI goes below 30 then stock is overload and stock is overbought when it goes above 70. 30 to 70 are considered a normal reading of a stock. General trend, finding deviations and failure swings can be detected by using RSI.

VOLATILITY ANALYSIS:

Volatility remained at 13.69% over last week and shows 11.21% volatility in last month. VOLATILITY is also measured by ATR an exponential moving average (14-days) of the True Ranges. ATR value stands at 1.19.

PROFITABILITY SNAP:

PERFORMANCE REVIEW:

DNA revealed weekly performance of 10.92%. The stock moved to 12.71% in last six months and it maintained for the month at -17.81%. The stock noted year to date performance at 10.38% and changed about 0.54% over the last three months. The stocks price situated at -29.59% from 52 week high and stock price seen at 41.21% when looking at 52 week low price.

ANALYSTS OPENION:

Looking ahead of 52-week period, the stock will achieve $14.83 price. This mean target price is expected by analysts.

The rest is here:
You Need to See this stock? Ginkgo Bioworks Holdings, (DNA) - The Union Journal

Country

United States of AmericaUS Virgin IslandsUnited States Minor Outlying IslandsCanadaMexico, United Mexican StatesBahamas, Commonwealth of theCuba, Republic ofDominican RepublicHaiti, Republic ofJamaicaAfghanistanAlbania, People's Socialist Republic ofAlgeria, People's Democratic Republic ofAmerican SamoaAndorra, Principality ofAngola, Republic ofAnguillaAntarctica (the territory South of 60 deg S)Antigua and BarbudaArgentina, Argentine RepublicArmeniaArubaAustralia, Commonwealth ofAustria, Republic ofAzerbaijan, Republic ofBahrain, Kingdom ofBangladesh, People's Republic ofBarbadosBelarusBelgium, Kingdom ofBelizeBenin, People's Republic ofBermudaBhutan, Kingdom ofBolivia, Republic ofBosnia and HerzegovinaBotswana, Republic ofBouvet Island (Bouvetoya)Brazil, Federative Republic ofBritish Indian Ocean Territory (Chagos Archipelago)British Virgin IslandsBrunei DarussalamBulgaria, People's Republic ofBurkina FasoBurundi, Republic ofCambodia, Kingdom ofCameroon, United Republic ofCape Verde, Republic ofCayman IslandsCentral African RepublicChad, Republic ofChile, Republic ofChina, People's Republic ofChristmas IslandCocos (Keeling) IslandsColombia, Republic ofComoros, Union of theCongo, Democratic Republic ofCongo, People's Republic ofCook IslandsCosta Rica, Republic ofCote D'Ivoire, Ivory Coast, Republic of theCyprus, Republic ofCzech RepublicDenmark, Kingdom ofDjibouti, Republic ofDominica, Commonwealth ofEcuador, Republic ofEgypt, Arab Republic ofEl Salvador, Republic ofEquatorial Guinea, Republic ofEritreaEstoniaEthiopiaFaeroe IslandsFalkland Islands (Malvinas)Fiji, Republic of the Fiji IslandsFinland, Republic ofFrance, French RepublicFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabon, Gabonese RepublicGambia, Republic of theGeorgiaGermanyGhana, Republic ofGibraltarGreece, Hellenic RepublicGreenlandGrenadaGuadaloupeGuamGuatemala, Republic ofGuinea, RevolutionaryPeople's Rep'c ofGuinea-Bissau, Republic ofGuyana, Republic ofHeard and McDonald IslandsHoly See (Vatican City State)Honduras, Republic ofHong Kong, Special Administrative Region of ChinaHrvatska (Croatia)Hungary, Hungarian People's RepublicIceland, Republic ofIndia, Republic ofIndonesia, Republic ofIran, Islamic Republic ofIraq, Republic ofIrelandIsrael, State ofItaly, Italian RepublicJapanJordan, Hashemite Kingdom ofKazakhstan, Republic ofKenya, Republic ofKiribati, Republic ofKorea, Democratic People's Republic ofKorea, Republic ofKuwait, State ofKyrgyz RepublicLao People's Democratic RepublicLatviaLebanon, Lebanese RepublicLesotho, Kingdom ofLiberia, Republic ofLibyan Arab JamahiriyaLiechtenstein, Principality ofLithuaniaLuxembourg, Grand Duchy ofMacao, Special Administrative Region of ChinaMacedonia, the former Yugoslav Republic ofMadagascar, Republic ofMalawi, Republic ofMalaysiaMaldives, Republic ofMali, Republic ofMalta, Republic ofMarshall IslandsMartiniqueMauritania, Islamic Republic ofMauritiusMayotteMicronesia, Federated States ofMoldova, Republic ofMonaco, Principality ofMongolia, Mongolian People's RepublicMontserratMorocco, Kingdom ofMozambique, People's Republic ofMyanmarNamibiaNauru, Republic ofNepal, Kingdom ofNetherlands AntillesNetherlands, Kingdom of theNew CaledoniaNew ZealandNicaragua, Republic ofNiger, Republic of theNigeria, Federal Republic ofNiue, Republic ofNorfolk IslandNorthern Mariana IslandsNorway, Kingdom ofOman, Sultanate ofPakistan, Islamic Republic ofPalauPalestinian Territory, OccupiedPanama, Republic ofPapua New GuineaParaguay, Republic ofPeru, Republic ofPhilippines, Republic of thePitcairn IslandPoland, Polish People's RepublicPortugal, Portuguese RepublicPuerto RicoQatar, State ofReunionRomania, Socialist Republic ofRussian FederationRwanda, Rwandese RepublicSamoa, Independent State ofSan Marino, Republic ofSao Tome and Principe, Democratic Republic ofSaudi Arabia, Kingdom ofSenegal, Republic ofSerbia and MontenegroSeychelles, Republic ofSierra Leone, Republic ofSingapore, Republic ofSlovakia (Slovak Republic)SloveniaSolomon IslandsSomalia, Somali RepublicSouth Africa, Republic ofSouth Georgia and the South Sandwich IslandsSpain, Spanish StateSri Lanka, Democratic Socialist Republic ofSt. HelenaSt. Kitts and NevisSt. LuciaSt. Pierre and MiquelonSt. Vincent and the GrenadinesSudan, Democratic Republic of theSuriname, Republic ofSvalbard & Jan Mayen IslandsSwaziland, Kingdom ofSweden, Kingdom ofSwitzerland, Swiss ConfederationSyrian Arab RepublicTaiwan, Province of ChinaTajikistanTanzania, United Republic ofThailand, Kingdom ofTimor-Leste, Democratic Republic ofTogo, Togolese RepublicTokelau (Tokelau Islands)Tonga, Kingdom ofTrinidad and Tobago, Republic ofTunisia, Republic ofTurkey, Republic ofTurkmenistanTurks and Caicos IslandsTuvaluUganda, Republic ofUkraineUnited Arab EmiratesUnited Kingdom of Great Britain & N. IrelandUruguay, Eastern Republic ofUzbekistanVanuatuVenezuela, Bolivarian Republic ofViet Nam, Socialist Republic ofWallis and Futuna IslandsWestern SaharaYemenZambia, Republic ofZimbabwe

Read more:
Snapchat chatter, DNA led to arrest in shooting death of Hitchcock teen - Galveston County Daily News

SANDI Sandrik, 51, a nurse, lives in Phoenix, Arizona, with husband Ken, 55, a warehouse driver.

She describes the remarkable story of how she found out her colleague was her brother.

5

5

Looking around the table, I smiled at my colleague Allen, who I was hosting for dinner. What was incredible was I had just learnt he was also my brother.

I had no idea that I was adopted until I was 11, when a friend blurted it out.

When I asked my parents, they admitted that my biological mum, named Anna, was a distant relative of the man I knew as my father.

Although some people in our town were already aware, it was a complete shock to me.

I loved my parents so much, I couldnt bring myself to ask more questions in case it hurt them, but I never stopped wondering, and as a teenager, I developed a fear of rejection.

In 1985, aged 15, I met Ken, and we married two years later when I was pregnant with our eldest child Ryan, now 33.

Life was good, and we went on to have our daughter, Hali, 30, and another son, Eric, 29, and I trained to be a nurse.

Sadly, my mum died in September 2013, followed by my dad in August 2016.

I was swimming in grief the night Dad died, when my phone lit up with a text from my biological mother Anna, whod got my number through family.

Shed promised my parents not to contact me while they were alive, but said shed always wanted me in her life.

She explained how shed become pregnant at 20 while dating a man called Gary, but that she was still in love with her ex.

Adoption within the family seemed the best thing to do, so she handed me over to Mum and Dad and lost touch with Gary.

I found out I also had a half-sister, Sophie*, now 52, and after messaging and talking on the phone for many months, in February 2017, I met both Anna and Sophie, and I felt a connection straight away.

We have a great relationship now, but it was a lot to take in, so for a long time I didnt even think about trying to find my biological father, too.

But then my kids paid for me to have a DNA test in November 2017.

The manufacturer connects you with other genetic relatives, and I realised this could be a way to track down my dad.

Six months later, I connected with a cousin, who shared Garys Facebook profile with me.

I didnt see anything of myself in him, and it took me two months to send him a message to introduce myself.

As time went on and I didnt get a reply, I tried not to think about him.

Then in summer 2019, a new nurse called Allen started at my work.

5

5

He was kind, thoughtful and like me calm under pressure, and I liked him immediately.

He kept saying he was sure that he knew me from somewhere, but I just shrugged it off.

Meanwhile, Id occasionally check Garys Facebook profile, still hopeful that hed reply, but he never did.

It was in December 2020, while looking through Garys friends list, that I spotted Allen.

When I saw him at work next, I asked how he knew my biological father Gary.

Oh my god, he replied. Hes my dad, too.

Bursting into tears, he pulled me into a hug, saying he was overjoyed.

Back home, I told Ken. Like me, he was in disbelief.

Allen and I exchanged numbers, and over the next few days I learned he was five years older than me and was three when Gary divorced his mum.

Allen wasnt close to Gary, but he was in his life. As we shared our stories, I felt our connection grow.

When we had a family meal in January 2021, I invited Allen and his wife Stacie to join us, and it was lovely.

Later that week, Allen spoke to Gary, who initially denied everything.

I can understand his reaction it was a shock for us all but he agreed to meet me at a lunch Allen organised.

I was nervous, but it was really nice to be together. Gary and I are now slowly getting to know each other, though weve not discussed much of the past yet.

My relationship with Allen has gone from strength to strength. Hes now close to my husband and kids, and we speak constantly.

My advice to anyone thinking of doing a DNA test is to be careful as there are many peoples feelings involved.

But for me, discovering Allen was the most wonderful surprise of all.

*name has been changed

5

We pay for your stories!

Do you have a story for The Sun news desk?

The rest is here:
A DNA test revealed my colleague was my brother he kept saying he knew me from somewhere but I shrugged i... - The Sun

If you're not sure where to start when looking for the next multi-bagger, there are a few key trends you should keep an eye out for. Amongst other things, we'll want to see two things; firstly, a growing return on capital employed (ROCE) and secondly, an expansion in the company's amount of capital employed. Ultimately, this demonstrates that it's a business that is reinvesting profits at increasing rates of return. So when we looked at the ROCE trend of Skyline Champion (NYSE:SKY) we really liked what we saw.

For those that aren't sure what ROCE is, it measures the amount of pre-tax profits a company can generate from the capital employed in its business. To calculate this metric for Skyline Champion, this is the formula:

Return on Capital Employed = Earnings Before Interest and Tax (EBIT) (Total Assets - Current Liabilities)

0.28 = US$200m (US$1.0b - US$289m) (Based on the trailing twelve months to October 2021).

Thus, Skyline Champion has an ROCE of 28%. In absolute terms that's a great return and it's even better than the Consumer Durables industry average of 15%.

See our latest analysis for Skyline Champion

Above you can see how the current ROCE for Skyline Champion compares to its prior returns on capital, but there's only so much you can tell from the past. If you'd like, you can check out the forecasts from the analysts covering Skyline Champion here for free.

Investors would be pleased with what's happening at Skyline Champion. The numbers show that in the last five years, the returns generated on capital employed have grown considerably to 28%. Basically the business is earning more per dollar of capital invested and in addition to that, 309% more capital is being employed now too. The increasing returns on a growing amount of capital is common amongst multi-baggers and that's why we're impressed.

In another part of our analysis, we noticed that the company's ratio of current liabilities to total assets decreased to 29%, which broadly means the business is relying less on its suppliers or short-term creditors to fund its operations. So shareholders would be pleased that the growth in returns has mostly come from underlying business performance.

To sum it up, Skyline Champion has proven it can reinvest in the business and generate higher returns on that capital employed, which is terrific. Since the stock has returned a staggering 434% to shareholders over the last three years, it looks like investors are recognizing these changes. With that being said, we still think the promising fundamentals mean the company deserves some further due diligence.

If you'd like to know about the risks facing Skyline Champion, we've discovered 1 warning sign that you should be aware of.

High returns are a key ingredient to strong performance, so check out our free list ofstocks earning high returns on equity with solid balance sheets.

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team (at) simplywallst.com.

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

More:
We Think Skyline Champion (NYSE:SKY) Might Have The DNA Of A Multi-Bagger - Simply Wall St

Illustration of the DNA molecule and its components. DNA is made up of two strands, a nucleotide ... [+] chain and a complementary chain, each one made up of phosphoric acids, sugar and bases (Adenine, Thymine, Guanine and Cytosine). (Photo by: BSIP/Universal Images Group via Getty Images)

Have you eaten any DNA lately? My bet is that youve eaten lots of it. DNA is not only safe to eat, its present in many truly delicious foods.

For example, chocolate has loads of DNA. Ice cream also has DNA, plenty of it. And lest you think DNA is only in desserts, its also found in hamburgers, cheese, bread, all kinds of sushi, and a very long list of other foods. Want to know which foods are DNA-free? Keep reading.

(Aside: why am I explaining that DNA is safe? Scientists reading this might say of course it is, whats the big deal? If youre among those, you dont need to read any further. But many people are afraid to eat DNA because they dont know what it is, and the name sounds a bit scary. In fact, a study in 2016 found that 80% of Americans thought that foods containing DNA should have a warning label.)

DNA contributes pretty much nothing to the taste of your food, which is sort of obvious given that its found in so many different-tasting foods. Thats because flavors are a very complex combination of many, many ingredients, and DNA is just one small part of most foods. If you were to purify DNA and taste it all by itself, it would taste slightly salty. If you want to watch someone trying this for himself, check out this video:

So how do we know that DNA is present in so many different foods? The explanation goes like this: all living thingsplants, animals, fungi, bacteria, and othersare composed of cells. Almost every cell in a plant or animal contains a copy of its genetic code, and that code is captured by DNA molecules. Think of DNA as a very, very long string of chemicals, or bases.

In rice, to choose just one example, each cell contains 12 chromosomes, and each chromosome is a long DNA molecule. The DNA strings in rice add up to about 430 million bases. So when youre eating rice, youre eating all of this DNA in every bite.

The wheat we use to make bread has even more DNA: every cell has about 16 billion bases. Thats 5 times more DNA than human cells have! But interestingly, the wheat we use to make pasta, called semolina or durum wheat, has only about two-thirds as much DNA as bread wheat (and only 14 chromosomes instead of 21). But I digress.

Thus any food that is derived from a plant or animal is almost certain to contain DNA, unless the food is processed so much that every cell from the original plant is removed or pulverized to bits, and the DNA is somehow removed (which normal food processing or cooking does not do). Theres no reason to remove the DNA, though, because its completely safe.

Pretty much every food that has DNA in it will also have RNA. RNA is safe to eat too! Some people have been concerned lately about RNA, which has been in the news frequently because it is used in two of the most effective Covid-19 vaccines, the ones from Pfizer/BioNTech and Moderna. Of course, injecting RNA into your arm is different from eating it, but both are very safe. (For more about RNA vaccines, see the article I wrote just a month ago, here.)

Now lets answer a question I posed at the top: what foods dont have DNA? The list is remarkably short:

Yep, thats it. Salt is a mineral, so it doesnt come from living things. And sugar is a simple molecule, C12H22O11, produced by plants such as sugar cane and sugar beets. The asterisk (*) next to sugar is there because unless the sugar is very pure, some DNA from the original plants is probably present, so it might not be DNA-free.

And if you want to wash down that salt and sugar with a DNA-free drink, you cant use coffee, tea, wine, beer, or fruit juice. All of them contain DNA.

Before I close, I should add that DNA stands for deoxyribonucleic acid. To some, the name is cause for concern: after all, acid cant be good, right? Well, in the case of DNA, it is good. Maybe we should call it nuclein instead; that was the name given to it by Friedrich Miescher, the Swiss scientist who first discovered DNA, in 1871.

Bottom line: DNA is in almost everything you eat, youve been eating it all your life, and theres nothing to worry about.

Continue reading here:
DNA Is Safe To Eat. RNA Isnt Bad Either. - Forbes

His brother, Johnny Little, currently lives in Atlanta. His DNA helped identify Frank, who was a guitarist and songwriter for the music group the O'Jays.

ATLANTA A four decade mystery has come to an end. Partial human remains found in 1982 in Ohio have finally been identified by police as Frank Little Jr., a former songwriter and guitarist for music group the O'Jays.

They were able to make that discovery thanks to his brother, Johnny Little, who lives in Atlanta, and other family members, who sent in their DNA.

Frank's cousin, Ross Little, tells 11Alive he did a DNA kit this year to trace his ancestors. He got a call from a detective not too long after.

The detective - they found that the John Doe they discovered years ago, matched my DNA," Ross said.

From there, Johnny says the detective then called the Atlanta Police Department to get ahold of him.

"The detectives came to my home and swabbed my mouth," Johnny said. "A couple of weeks went by and then they called and said it's confirmed that he was your brother. Oh, I broke up crying."

Johnny says he last saw his brother in 1976 after starting a brand new job for a plastic machinery company.

"I got my first check, so I run into him and I showed him my check. He said, 'Oh, man, that's a nice book. Congratulations on your new job', And then we parted," Johnny recalled.

Johnny says Frank had two children and served in the U.S. Army, deploying to Vietnam.

He also spent a few years playing guitar and writing songs for the O'Jays. After his death, the band was inducted into the Rock & Roll Hall of Fame in 2005.

"I used to go watch him play at different times," Johnny remembered. "He tried to teach me how to play the guitar. He wanted us to be like to Everly brothers.

Johnny was the youngest of the family of five brothers and three sisters. Frank was just one year older than him.

"He used to draw, paint, and he wrote songs. He could he could pick up a tree trunk and carve it and sell it. He used to make his own clothes. Yeah, a lot of talent," Johnny added.

Their mother died giving birth to what would've been a fourth sister when Johnny was only 3 years old.

"They called me and asked me, 'Does the name Laverta mean anything?' And I burst out crying too because that's my mother's name. And that's an odd name: Laverta," he added.

Johnny says he last saw his brother in 1976 in Cleveland, Ohio, and moved to Atlanta a few years later.

In 1982, the partial human remains were found in a garbage bag behind a business southeast of Cleveland.

The detective told me that they found the head behind an abandoned building, and 50 feet further is where they found the plastic bag," Johnny said. He was inside the plastic bag. Cut up."

According to the Twinsberg Police Department in Ohio, his identification was made through the collaborative efforts of the department, the DNA Doe Project, the Ohio Attorney Generals Office Bureau of Criminal Investigation, and the Summit County Medical Examiners Office.

It adds that: "Franks partial remains were recovered in a garbage bag behind a now-closed business on Cannon Road. The remains were that of an African-American male, 20 to 35 years of age, approximately 56 tall, and he may have had adolescent kyphosis, a curvature of the spine."

His manner of death has been ruled a homicide by Dr. Lisa Kohler of the Summit County Medical Examiners Office.

"Im grateful that DNA proved that it was him because we always wondered where he was. I used to worry about him," Johnny added.

Few details were known about the circumstances of his disappearance or death, the department said.

According to NBC News, a representative for the O'Jays said Wednesday morning, "we wish his family and friends closure to what appears to be a very sad story."

I used to go watch him play at different times. He tried to teach me how to play the guitar, but your fingers get real sore when you start out. When my fingers got like that, I quit. He wanted us to be like the Everly brothers and play guitar," Johnny said while laughing.

View original post here:
Remains found in garbage bag in 1982 identified as former O'Jays member, thanks to DNA from brother in Atlanta - 11Alive.com WXIA

INDIANAPOLIS There will be occasions when Carson Wentz carries the day.

He passed for a career-high 402 yards and two touchdowns in the overtime loss at Baltimore, and everyone remembers those 26 consecutive drop-backs in the loss to Tampa Bay. Hes tied a career-best with a 100-plus passer rating in seven games, has 22 touchdowns against just five interceptions, and had a six-game stretch where he delivered at least two TD passes in each.

And in case youve forgotten, the NFL remains a quarterback-driven venture.

The Indianapolis Colts arent exactly an outlier, but neither are they conformists.

Listen to Frank Reich.

What matters to me is that our DNA our identity from day 1 when I got here from the last place I was at (is) were going to run the football, he said. Thats what I believe offensively as a team you have to be able to do to win consistently in this league.

Im not saying there is not ever roster dynamics that could make it otherwise, but the idea coming in was we want to be able to run the football.

Thats been Reichs MO.

I know what it feels like to be on a team that can run the football, he said. Ive experienced that my whole life as a quarterback and as a coach.

As offensive coordinator of the 2017 Super Bowl-winning Philadelphia Eagles, Reich relied on the NFLs No. 3-ranked run game.

During his formative years as the Buffalo Bills backup quarterback, he was part of an up-tempo offense that was viewed as pass-happy, but in fact was routinely one of the leagues most prolific on the ground. It ranked in the top 10 from 1988-95, and was No. 1 in 1991-92.

Its a powerful thing to be able to run the ball, Reich said. It doesnt necessarily mean 50 times or 200 yards. It just means you can run the ball when you want to run the ball, and you can run it effectively.

I really think if you want to be a truly dynamic offense, which we want to be, you have to be able to execute in both areas. Were always striving (for) that, but for us, we always say the foundation for that is the run game.

The man has put his game plan where his mouth is. Consider:

Pro Bowl center Ryan Kelly traces the Colts run-centric approach to a week 7 meeting with Buffalo in 2018. They had staggered to a 1-5 start in Reichs first season, but finally seemed to embrace that DNA Reich mentioned.

Very distinctive game, Kelly said. On record, we werent very good. I think we put (37) on them.

That was really what changed the mindset for this team.

The Colts pounded the Bills into submission: 220 yards on 37 rushing attempts in a 37-5 blowout. The next week, they rushed 40 times for 222 yards in a 42-28 win at Oakland.

Since then, Kelly insisted, weve always been a run-first team.

First with Mack, who led the team in rushing in 2018-19, and now with Taylor.

The teams 2020 second-round draft pick has emerged as the undeniable catalyst for an offense that ranks 11th in yards per game (368.1), 2nd in rushing (151.7) and 4th in scoring (28.5). That rushing average, by the way, would be the Colts highest since 1985 (152.4).

Taylor has rushed for at least 100 yards in seven of his last 10 games and is on pace for 1,762, which would eclipse Edgerrin James club record (1,709 in 2000).

But with each passing week, the target on Taylors back has grown. Teams have crowded the line of scrimmage, making it more difficult for him and requiring Wentz to do more in the passing game.

I mean, obviously youre going to see more attention, more stacked boxes and then it falls on us, Taylor said. It leans on us as an offense in order to make sure that were all on our alignments and assignments.

Especially when you have a loaded box, you have to make sure that technique is on and make sure were fitting guys up. I have to do a great job of bringing guys to blocks and not just leaving it to the o-line and the receivers to get guys covered up as well.

All of that makes Saturday nights showdown with the New England Patriots in Lucas Oil Stadium so intriguing.

The Colts want to Run the Damn Ball.

The Patriots are among the best at not allowing that to happen, and dont let their lackluster ranking fool you.

New Englands run defense ranks 19th in yards per game (114.5) and yards per attempt (4.4). But those numbers are somewhat skewed by a week 12 win over Tennessee. While the Patriots were rolling 36-13, the Titans were piling up 270 yards most in the NFL this season on 39 attempts.

In its other 12 games, the Patriots have allowed averages of 101.5 yards per game and 4.1 per attempt; the 12-game yield on the ground would rank 8th. During their seven-game winning streak, theyre allowing a league-low 10 points per game.

And lets not forget coach Bill Belichick is a master at taking away whatever an opponent does best.

I mean, hes the best ever, Reich said. This is the No. 1 defense. Its a great challenge. We know theyre very well-coached. Theyre physical, theyre disciplined.

Theyve got playmakers on defense. They turn the ball over.

Added Wentz: Theyre very specific I would say within each game on how they want to stop an opponent. For us, it will be, Hey, come out early, lets get a feel for whats the flavor of the day. How are they trying to stop us?

Whatever approach Belichick takes, the design will be to limit Taylors effectiveness.

For sure, for sure, Wentz said. I would say a lot of teams have done that as of late. For us, JTs still as good as it gets at that position in the league and we trust our big boys up front, no matter what the looks, to get it done.

For us, its going to still be the same thing. Were going to try to run the ball and Im confident were going to be able to. Were going to still do our thing. Then, like we always say within a game, make adjustments as needed.

Along with the normal adjustments, it will be incumbent upon Reich and offensive coordinator Marcus Brady to remain committed to their run game, unless the Patriots are able to take it away with loaded fronts and creativity.

Explosive plays have been a major part of Taylors breakout season. He leads the NFL with 10 rushes of at least 20 yards and three that have gained at least 40. Taylor has generated the leagues two longest runs this season: 83 yards against Houston in 6 and a 78-yard TD against the Jets in week 9.

If you get it to him enough, hes going to create big plays, Reich said. But at the same time, we dont want him to pound his head up against a wall play-in and play-out.

That goes back to that mix of how much is too much or how much isnt enough, and thats a game-by-game, really series-by-series feel.

Listen to the Colts Blue Zone Podcast for weekly coverage and analysis of the Indianapolis Colts.

You can follow Mike Chappell on Twitter at@mchappell51.

View original post here:
Frank Reich: DNA is were going to run the football - Fox 59

The US should consider restricting the export of its human genomics data to guard against potential future attacks by Russia or China with DNA targeted weapons, according to a scientific risk assessment.

This raises the prospect that the genomics data which in the past 20 years has become the lifeblood of large swathes of medical and public health research could be restricted for security reasons. China is already allegedly imposing controls on the use of its own information.

Theres a recognition that theres a military dimension, military potential to this, said Robert Shaw, an export control expert at the Middlebury Institute of International Studies, Monterey, California, co-author of the risk assessment report. There is a dual-use dimension, absolutely, he said.

For now, the prospect of a DNA-targeted weapon aimed at whole countries, ethnicities, families or individuals is the stuff of a James Bond adventure - literally. In 007s latest outing, No Time to Die, the villain of the piece threatens to eradicate millions of people, using nanobots programmed to attack specific DNA sequences.

Reassuringly, the Scientific Risk Assessment of Genetic Weapon Systems, says that the capabilities in No Time to Die remain fictional, at least for now.

Targeting genetic markers present in one population would inevitably spill over into other countries due to interbreeding, it says, making a precise weapon difficult to create. The USs ethnic diversity therefore gives the country a protective effect against attack, it concludes.

In addition, launching a genetic weapon into a population remains a major challenge.

While raising the alarm, Shaw said there are currently no specific, confirmed military programmes developing genetic weapons.

However, such weapons could become increasingly feasible in the next 5 15 years due to technological advances.

While the targeting approaches described in this report are technically challenging and data hungry, because of ongoing research these technical barriers are likely to erode over time, the report says.

Even if it is hard to target entire countries, genetic weapons could prove uniquely suited to carrying out covert assassinations, where lack of attribution is paramount.

The case for encryption

As the report notes, Once genomic information is shared, it cannot be unshared.

Given these risks the US should, Explore applicability of national-level export controls on human genomic information, the report recommends.

The US should also start to differentiate between human and non-human genomics data. The exception to that is the genomes of staple crops, the genomic homogeneity of which makes them particularly vulnerable to targeting by a genetic weapon, the report says.

The prospect of DNA being weaponised strengthens the case for encrypting and limiting the sharing of genetic data, said Allison Berke, director of advanced technology at the Institute for Economic Policy Research at Stanford University.

But privacy concerns are an even stronger reason for greater control, because genetic information can be used to track individuals, identify family relationships and medical conditions, she said.

Berke stressed that currently, There is not enough genetic variation between nations to make a genetically-targeted weapon sufficiently accurate, and there are easier means to target individuals than a customised genetic weapon.

Nonetheless, China-focused national security think tanks in the US are increasingly worried, according to Shaw. This topic is already coming up in those circles, he said.

While the US has been open in sharing genomics data, China has been increasingly protective of its own, and in 2019 introduced new legislation restricting foreign access, the report says.

Shaw said that there is informed speculation that China is worried about the prospect of genetic weapons because its own population is relatively ethnically homogenous. That may lend itself togenetic weapons targeting a bit more easily, than lets say by comparison the US, which is a much more ethnically diverse population, he said. Science|Business has contacted the Chinese Academy of Sciences for a comment.

Continual monitoring

The report is not the first to warn that genetic data could have a military use. Last year, the US National Academy of Sciences (NAS) published a report called Safeguarding the Bioeconomy, which discusses if only briefly - the prospect of genetic targeting of populations.

The idea poses a number of technical difficulties, it says, but warns that new biotechnologies are continually being developed and the area requires continual monitoring.

Concerns have also been raised during the past year in the US and Europe about the harvesting of genetic data by private Chinese companies. The focus is less on the risk of a genetic weapon, and instead on privacy, blackmail or intelligence concerns - hostile governments could identify people predisposed to depression, for example.

The propensities of national leaders to act in certain ways, which could be influenced by their genetic makeup, could well be of interest to adversarial intelligence agencies, says the NAS report.

There are further concerns over how genetic data could intersect with artificial intelligence. AI may enable a pathogen to be specifically engineered for lethality or to target a genetic profilethe ultimate range and reach weapon, warned the final report of the USs National Security Commission on Artificial Intelligence, released earlier this year.

It also sounds the alarm over Chinese genomics data gathering. The US cannot afford to look back in 10 years and be surprised by the biotechnology equivalent of Huawei, it cautions.

Currently, genetic data is not explicitly part of any of the various intergovernmental agreements that control the export of dual-use technologies, said Shaw. There are generally broad exemptions for scientific research, and a general reluctance to control the flow of raw sequence data, as opposed to the actual means to create a weapon.

Any inclusion of genetic data in these regimes would really represent a fundamental change in export control and get a strong pushback from academic communities who use it in their work.

Even so, privacy concerns may start to restrict genetic data flows. The EU is currently working out to what extent genetic information is protected by its General Data Protection Regulation, said Berke.

Any regulatory dimension to the sharing of genetic data, its probably going to be privacy related, said Shaw. And the same would hold true in the US.

Read more:
Call to restrict sharing of genomics data over fears of DNA-targeted weapons - Science Business

A highly regarded scientific journal has retracted a paper based on DNA samples from nearly 38,000 men in China, including Tibetans and Uyghurs who almost certainly did not give proper consent.

The rare retraction by the journal, Human Genetics, follows a two-yearcrusade by a Belgian scientist to push publishers to investigate research that he and others say is complicit in human rights violations.

The papers authors used DNA samples from across China to assess genetic variation among and within ethnic groups. The journals editors retracted the paper because of doubts about the informed consent process. According to a retraction notice published December 11, three authors, including the two lead authors, agreed to withdraw the paper.Human Genetics is published by Springer Nature, which retracted two other papers for similar reasons in August and September.

The scientist who spearheaded the retraction campaign, Yves Moreau, said he was thankful that Springer Nature had investigated but that there was more work to be done, noting that the papers findingshad been used in over two dozen other papers. This is not only a matter of informed consent, but also a matter of retracting and not publishing research clearly linked to serious harm, said Moreau, who is a bioinformatician at the University of Leuven in Belgium. It raises the question of what will happen to those almost 40,000 DNA profiles. The anonymized profiles remain in an online database in Germany that can be freely queried by anyone.

At least nine of the papers 30 co-authors are affiliated with Chinese police departments or police academies, and several others are affiliated with forensic science departments at Chinese universities. Researchers are often given co-author slots in exchange for collecting samples and data, said Moreau, making it likely that at least some of the Chinese samples were collected by police. Chinas Ministry of Public Security, which oversees police across China, has been building out a national DNA database, overthe objections of human rights activists.

One of thelead authors on the retracted paper, Lutz Roewer, oversees the German database, which is housed atthe Charit research hospitalin Berlin. Called the Y-Chromosome Haplotype Reference Database, or YHRD, it is often used by police around the world who are seeking more information about specific DNA samples. It has recently come under scrutiny for including DNA from the persecuted Roma ethnic group as well as Uyghur and Chinese DNA that ethicists presume was collected without informed consent.

Roewer did not immediately respond to a request for comment.

A facility believed to be a reeducation camp where mostly Muslim ethnic minorities are detained is seen in Artux, north of Kashgar in Chinas western Xinjiang region, on June 2, 2019.

Photo: Greg Baker/AFP via Getty Images

An explosion in accessible DNA technologies has also sparked police misuse in the United States. In China, said Emile Dirks, adoctoral candidate at the University of Toronto who studies Y-STR data collection, you have a nationwide, multiyear campaign to target individuals for genealogical or genomic collection, none of whom are targets in an investigation, nor are they known to be or suspected of being related to someone who is a target of a criminal investigation.

YHRD, the German database, is the largest collection of Y-STR samples in the world, containing 300,000 profiles. The profiles do not have names attached, but police often use them to zero in on a likely geographic origin for a suspect, then use that marker to make assumptions about the suspects ethnicity.

If our community is perceived to be condoning or even tolerating human rights abuses, public trust in genetics will rapidly crumble.

Moreau first raised concerns about the paper with Springer Nature editors in June 2020. This past July, he wrote to the journals editorial board to ask for help, appealing to the Hippocratic oath that many took when they became doctors. Public trust in human genetics depends on our communitys ability to transparently abide by its moral duties, he wrote. If our community is perceived to be condoning or even tolerating human rights abuses, public trust in genetics will rapidly crumble.

In a later email to the editorial board, he worried that his inquiries were being stonewalled because of strategic and business considerations by publishers, who are afraid of poking a mighty bear, referring to the financial interests of journals operating in China.

Springer Nature did not immediately respond to The Intercepts requests for comment.

Moreaus email to the editorial board sparked a heated discussion. One scientist responded to his comment about business interests, observing that science was slipping from the hands of actual practicing scientists and not just in human and medical genetics.

The work included DNA probes of sources that did not respect ethical obligations, thereby violating contemporary ethical norms and regulations, Gudrun Rappold, a geneticist at the University of Heidelberg and a member of the editorial board, wrote to The Intercept. She said that she had previously used Y chromosome data in her own work but that she saw the retraction as a warning sign for the future.

In August, Moreaus emails to the editorial board of another journal that had published fraught research, Molecular Genetics & Genomic Medicine, prompted eight scientists to resign in protest.

China is the best and the clearest example that one can think of because we all agree that human rights violations in China are so severe, said Veronika Lipphardt, a science historian at the University of Freiburg in Germany who,along with Rappold,recently authored a comment article in Nature on abuses involving Roma DNA. But we should not forget to look elsewhere. A lot of data from marginalized populations around the world, in nondemocratic regimes as well as in democratic countries, has been collected in similar ways by police forces.

Correction: December 14, 2021Thisarticle has beenupdated to clarify that the database containing the anonymized DNA profiles on which the retracted Human Genetics paper was based does not require registration and can be queried by anyone with access to the internet.

View post:
Journal Retracts Paper Based on Uyghur DNA - The Intercept

STONY BROOK, N.Y., December 15, 2021--(BUSINESS WIRE)--Applied DNA Sciences, Inc. (NASDAQ: APDN) (Applied DNA or the "Company"), a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing and nucleic acid-based technologies, and Stratum Reservoir (Isotech), LLC ("Isotech"), a division of Stratum Reservoir and a leader in laboratory stable isotope analysis, a technique used for fingerprinting naturally occurring organic compounds such as cotton, today announced that they have entered into a Memorandum of Understanding (MoU). Under the terms of the MoU, Applied DNA will deploy Isotechs isotopic analysis (IA) as a confirmatory assay for cotton genotyping, the process through which cotton DNA is utilized to determine cotton fiber and fabric origin forensically. The MoU is expected to be followed by a definitive agreement between the companies.

The signing of the MoU follows the joint presentation of initial data by the companies at an American Apparel and Footwear Association event that describes a methodology and findings for the successful determination of Egyptian cotton fiber, yarn and fabric origin using cotton genomics with affirmation by IA. The complementary use of IA to Applied DNAs CertainT platform for textile traceability yields a continuity of forensic data across the entirety of a natural fiber-based value chain from source to finished goods to ensure adherence to social (avoidance of products made with forced or slave labor) and environmental practices (sustainable, organic) aligned with regulatory and consumer expectations. Per the MoU, the companies will support business development opportunities for cotton traceability. They will also continue to build and compile a global database of cotton, yarn, and fabric samples from known sources to broaden the application and utility of IA.

MeiLin Wan, vice president of Textile Sales at Applied DNA, stated, "The use of IA complements our CertainT platform to deliver what we believe is a best-in-class, multi-layered approach to supply chain traceability and assurance across the entirety of natural fiber-based value chains. With CertainT, once origin is established, we deliver certainty that we believe is immutable and forensic from source-to-shelf. The power of DNA is now augmented with IA."

Story continues

"Stable isotope analysis is a powerful tool that we have historically used in the oil and gas industry," said Steven Pelphrey, Director of Stratum Reservoir (Isotech), LLC. "Through our collaboration with Applied DNA, we can now more broadly apply our proven technology and techniques to the textile industry. This both enhances Applied DNAs CertainT platform with an additional layer of geographic provenance and delivers an unmatched solution to the marketplace."

About Applied DNA Sciences

Applied DNA is commercializing LinearDNA, its proprietary, large-scale polymerase chain reaction ("PCR")-based manufacturing platform that allows for the large-scale production of specific DNA sequences.

The LinearDNA platform has utility in the nucleic acid-based in vitro diagnostics and preclinical nucleic acid-based drug development and manufacturing market. The platform is used to manufacture DNA for customers as components of in vitro diagnostic tests and for preclinical nucleic acid-based drug development in the fields of adoptive cell therapies (CAR T and TCR therapies), DNA vaccines (anti-viral and cancer), RNA therapies, clustered regularly interspaced short palindromic repeats (CRISPR) based therapies, and gene therapies.

The LinearDNA platform also has non-biologic applications, such as supply chain security, anti-counterfeiting and anti-theft technology. Key end-markets include textiles, pharmaceuticals and nutraceuticals, and cannabis, among others.

Leveraging its deep expertise in nucleic acid-based technologies, the Company has also established safeCircle, a high-throughput turnkey solution for population-scale COVID-19 testing. safeCircle is designed to look for infection within defined populations or communities utilizing high throughput testing methodologies that increase testing efficiencies and provide for rapid turn-around-times. The Company has also submitted a request for an EUA-authorization for its LineaTM SARS-CoV-2 Mutation Panel, an assay-based panel for the detection of certain SARS-CoV-2 genetic mutations.

Visit adnas.com for more information. Follow us on Twitter and LinkedIn. Join our mailing list.

The Companys common stock is listed on NASDAQ under ticker symbol APDN, and its publicly traded warrants are listed on OTC under ticker symbol APPDW.

Applied DNA is a member of the Russell Microcap Index.

About Stratum Reservoir (Isotech), LLC

Isotech is a leading provider of laboratory services and equipment designed to deliver scientific insights for customers around the world, including specializing in high-precision carbon, hydrogen, oxygen, nitrogen and sulfur-isotope analysis for a variety of industries. Isotech is a member of the Stratum Reservoir group of companies, which operates rock and fluids analysis laboratories to enable the discovery and sustainable development of energy resources through applied geosciences.

For more information, visit http://www.stratumreservoir.com and follow us on LinkedIn.

Forward-Looking Statements

The statements made by Applied DNA in this press release may be "forward-looking" in nature within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe Applied DNA's future plans, projections, strategies, and expectations, and are based on assumptions and involve a number of risks and uncertainties, many of which are beyond the control of Applied DNA. Actual results could differ materially from those projected due to its history of net losses, limited financial resources, limited market acceptance, including Applied DNA's ability to successfully enter into commercial contracts for the implementation of its CertainT platform, the unknown ability to identify and commercialize large numbers of cotton geographic biomarkers, the uncertainties inherent in research and development, and various other factors detailed from time to time in Applied DNA's SEC reports and filings, including our Annual Report on Form 10-K filed on December 9, 2021, and other reports we file with the SEC, which are available at http://www.sec.gov. Applied DNA undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date hereof or to reflect the occurrence of unanticipated events, unless otherwise required by law.

View source version on businesswire.com: https://www.businesswire.com/news/home/20211215005459/en/

Contacts

For Applied DNA: Investors: Sanjay M. Hurry, 917-733-5573, sanjay.hurry@adnas.com Program Manager: MeiLin Wan, 631-240-8849, meilin.wan@adnas.com Web: http://www.adnas.com Twitter: @APDN

For Isotech: Media Inquiries: Jason Buchman, (832) 375-6800, jason.buchman@stratumreservoir.com Program Manager: Steve Pelphrey, (217) 398-3490, steven.pelphrey@stratumreservoir.com

Follow this link:
Applied DNA and Stratum Reservoir (Isotech) Sign Memorandum of Understanding to Leverage Isotopic Analysis for Enhanced DNA-Based Cotton Authenticity...