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Category Archives: Psychedelics

Expanding consciousness – 48 Hills

Posted: August 1, 2017 at 6:26 pm

At some point, humankind will look back and figure out what to make of our heavy usage of psychedelics at music festivals. Despite the fact that mega-events provide probably the worst atmosphere for astral introspection, many peoples first mushroom or acid trips still happen at mobbed festivals or maybe the hardest trip theyll ever trip will take place at one. Hello, 21-year-old me at Reggae on the River. (I am not ashamed.)

The ritual of ingestion is often articulated in traditional cultures by a shaman or a guide well-read in the ways of certain substances. But in contrast with ayahuasca ceremonies, at Coachella or Burning Man psychedelic use is presided over by musicians on a stage set thousands of people away or by a friend who is just as dehydrated and medicated as you are or no one, when a overpowering wave of crowd splinters a crew.

Lacking a safe container to trip in, psychedelic complications are bound to happen in the haphazard setting of festival madness. Psychedelic users who become violent or otherwise unresponsive to official suggestion via a difficult trip can wind up at the hospital or worse, jail. Neither place is likely to alleviate the paranoia or fear theyre experiencing.

Drug research and education organization MAPS (Multidisciplinary Association For Psychedelic Studies) stepped into this disconnect when it raised the first incarnation of its Zendo Project at Burning Man in 2012. The on-site counseling program complimented MAPS larger mission to advocate for the therapeutic uses of psychedelics. The groups work often focuses on the way that drugs can be used to open up healing emotional pathways, such as a 2016 study that looked at the effects of MDMA on people suffering from PTSD.

The term psychedelic means mind manifesting, which means that our conscious mind becomes aware of subconscious things, says Sara Gael, MAPS director of harm reduction and Zendo Project organizer who has been involved since the year the program came to life and is a firm believer in the benefits associated with responsible usage of the drugs. Thats what therapy is about, exploring the subconscious and the aspects of self that society has taught us to repress.

In the uncertainty of festival chaos, worries about personal sanity or safety can complicate a psychedelic trip, rendering it all but impossible to stay open to the painful realizations that psychedelics can trigger. The Zendos infrastructure responds to this construct; volunteers erect a tent where triggered festival attendees can rehydrate, lie down, and/or snack, in addition to connecting with trained souls ready to sit with them through any threatening visions or panic-inducing paranoias.

Some of the more challenging cases we experience are people who are really frightened, who might then become aggressive, or try to run away, or feel really lost or paranoid, says Gael. Those are some of the more difficult situations to work with because were trying to keep that person physically safe. Thats why we work in collaboration with medical and security.

Today, the Zendo Project has helped 2,900 people at large events, teaming up with security and medical festival staff so that attendees receive the best treatment for their particular situation. Given the projects success, it is pleasant to imagine a larger diversity of gatherings in which Zendo-like harm reduction efforts were present. Currently, the program is limited to Burning Man and its regional events from South Africa to San Diego, in addition to the other transformational endeavors (Lightning in a Bottle, Costa Rican yoga and spirituality fest Envision.)

The Zendo Project is looking to expand, and is currently in the middle of a fundraising drive. And MAPS just publishedThe Manual of Psychedelic Support, a thick tome available for free download.

The manual outlines the logistics behind setting up a Zendo Project-like space, not to mention the inclusion of a fascinating history of harm reduction in modern Western festival culture (the original Woodstock festivals Hog Farmers, founded by Wavy Gravy, are considered pioneers in the area) and the Zendo Projects guiding principles for interactions with those on tough trips: creating a safe space, sitting not guiding, talking through and not down, and difficult is not the same as bad, in Gaels summarization.

Gael is quick to note that the core principles can even be self-applied, if you can remember them should you enter into a difficult trip yourself. When asked for a couple quick pointers for those finding themselves on shaky psychedelic ground, she ventured: What is coming up, try to turn into it rather than away from it, because what we resist, persists. Try to find a safe space away from noise with people that you trust. Find someone who is able to sit with you even if theyre not formally trained, who is not freaking out. Trying to connect with your breath and body, connecting with nature can be really helpful, finding a tree.

She adds that if youre still feeling shaken up even after youve become sober, MAPS has published a list of therapists who are educated in psychedelic integration, or the practice of connecting the dots between psychedelias half-processed self realizations.

It is clear that modern day Western society takes psychedelics under much different circumstances than the cultures that previously utilized the substances. The ritual of loading ones car up with friends and alcohol en route to Electric Daisy Carnival has little in common with the temazcals and sacrament of a Navajo peyote ceremony.

MAPS makes it clear that as part of a harm reduction strategy, the Zendo Project simply responds to the reality that this is the current situation, says Gael. And that despite policy, [psychedelic usage] is going to continue. After nearly 50 years of practice, however, new forms of psychedelic guidance in certain modern day sites of cultural ritual are being developed a nascent safety net for the psychedelic voyagers of today.

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Expanding consciousness - 48 Hills

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What Has Awe Done for Me Lately? – HuffPost

Posted: July 31, 2017 at 10:28 am

What is the value of awe and mystic experience? For starters, it reduces the me that wants things done for it, or at least offers temporary relief from this grasping me. Mystic experience, whatever links it occasions, offers a kind of holiday from ordinary reality. In this expansive space, the world can be felt as less self-centered, and more inter-connected. In many spiritual traditions, this shift is called awakening, or at least the start of it. Awakening is not an entertainment (lets get high) but a jewel (lets get real).

We have Aldous Huxley to thank for one of the first post-war accounts of a day transformed by a psychedelic (it was mescaline). Borrowing from William Blake, he called his book The Doors of Perception (1954). What he described was things seen in a state of awe. Many other great writers have explored the phenomenon of mystical experience occasioned by what a friend of mine calls mindful molecules, and some of their work will be listed near the end of this piece, reports subsequent to Huxleys.

These writers were interested in classic psychedelics not to alleviate or cure a health condition or reduce anxiety, much less to create a colorful internal light show, but rather to induce a state of awe Why?

They all refer to the ability of classis psychedelics to occasion mystical experience (or in a cautious phrase in a report about psilocybin, mystical-type experience). Professor Ralph Hood had not yet developed his mysticism scale in time for Wassons 1954 account of a psilocybin mushroom ceremony near Oaxaca, but the first word about the experience in Wassons account was, awestruck.

One interpretation of an experience of awe could be to reinforce a religious allegiance, whether, for example, Buddhist. Christian, Hindu, or Islamic. In each off these traditions, an allegiance has been strengthened by a mystic experience with or without the use of a mindful molecule. In this article, however, rather than get involved in theology, I want to stay with the experience occasioned by a classic psychedelic, prior to any interpretation of it.

We can all agree that the experience is radically different than ordinary reality, causing a habitual tendency to call it sacred and to assume it descends upon us from, or connects us with, another realm. However, Occams Razor suggests that were making a giant assumption if we assert that something very different from ordinary reality is necessarily transcendental. It might be, but it might equally represent access to a function of the human brain that is ordinarily absent or hidden.

As a rhetorical strategy, the claim of access to a realm in the bailiwick of spiritual leaders has some advantages. In the U.S. our idea of religious freedom might extend to the use of classic psychedelics. So far, this argument has succeeded only in the case of the Native American Church, which legally uses peyote in its ceremonies for hundreds of thousands of worshippers from one race,, and of a couple of offshoots of syncretic Brazilian churches (offshoots both located in the U.S. West).

Our courts seem to respect antiquity of practice. The native Americans have been doing their peyote ritual for a long time, and the Brazilian churches are linked to ancient shamanic practices involving ayahuasca in the Amazon basin. According to The Road to Eleusis, many of the ideas of Western civilization arose from people initiated through an annual ceremony that appears to have featured a group envisioning induced by a psychedelic agent in the kykeon and that continued for as long as two thousand years. A pause since the fourth century does not alter the antiquity of the practice.

According to the Road to Eleusis, the mysteries could be resumed now and offer benefits to our culture, as they did to the culture of ancient Greece and to initiates from the Roman empire. In a word, they could become again a part of normal life.

Now for the bibliographic note:

Appreciation for awe has appeared in a string of writings after Huxley on spiritual uses of psychedelics. Examples include:

At the time of the writings cited, Wasson was a New York banker and a mycologist; Watts, a British clergyman transposed to California; Smith, a philosopher of religion and former professor at various universities including MIT; Forte, a teacher and an editor; Hofmann, a chemist at Sandoz in Basel and the discoverer of LSD; Ruck, a classicist at Boston University;; Doblin, the founder of MAPS; Badiner, a student of Buddhism and an editor; Griffiths, a professor at Johns Hopkins.

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New book about psychedelics and weird human experiences – Boing Boing

Posted: July 26, 2017 at 4:26 pm

David Luke, a University of Greenwich psychology lecturer and researcher of high weirdness, has a new book out with the compelling title of Otherworlds: Psychedelics and Exceptional Human Experience. Based on the blurb, it sounds like an absolute trip:

A psychonautic scientific trip to the weirdest outposts of the psychedelic terrain, inhaling anything and everything relevant from psychology, psychiatry, parapsychology, anthropology, neuroscience, ethnobotany, ethnopharmacology, biochemistry, religious studies, cultural history, shamanism and the occult along the way.

Staring the strange straight in the third eye this eclectic collection of otherworldly entheogenic research delivers a comprehensive and yet ragtaglledy scientific exploration of synaesthesia, extra-dimensional percepts, inter-species communication, eco-consciousness, mediumship, possession, entity encounters, near-death and out-of-body experiences, psi, alien abduction experiences and lycanthropy. Essentially, its everything you ever wanted to know about weird psychedelic experiences, but were too afraid to ask

"Otherworlds: Psychedelics and Exceptional Human Experience" (via Daily Grail)

In Paper Girls, the celebrated comics creator Brian K Vaughan (Saga, Y: The Last Man, etc) teams up with Cliff Chiang to tell a story thats like an all-girl Stranger Things, with time-travel.

To call Shopsins a Greenwich Village institution was to understate something profound and important and weird and funny: Shopsins (first a grocery store, later a restaurant) was a kind of secret reservoir of the odd and wonderful and informal world that New York City once represented, in the pre-Trumpian days of Sesame Street and Times Square sleaze: Tamara Shopsin grew up in Shopsins, and Arbitrary Stupid Goal is her new, no-muss memoir, is at once charming and sorrowing, a magnificent time-capsule containing the soul of a drowned city.

There are three more stops on my tour for Walkaway: tomorrow at San Diego Comic-Con, next weekend at Defcon 25 in Las Vegas, and August 10th at the Burbank Public Library.

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Psychedelics and Normality – HuffPost

Posted: at 1:30 am

The official U.S. response to classic psychedelics has been primarily a defense of existing normality. The response was aroused, for example, by the drop out kicker in Tim Learys famous motto (turn on, tune in, drop out). It was shaped by perceived links to social disarray caused by claims of equality from blacks, women, people dismissed as shiftless, and foreigners who resented intervention (such as in Vietnam).

My own introduction to the drug issue came from a college student when I was a teaching assistant at Stanford in a course on personality theory. It was back in the late 1960s. I was told this pill is really great, this student reported being assured at a frat party. Swallow it and get ready for a really good time. He didn't even ask what the pill was said to be, much less seek data on what it actually contained. He just swallowed. LSD was soon made illegal. (As we will see below, this was far from an ideal set and setting.)

When U.S. research on psychedelics was allowed to resume, decades later, it was largely for projects that explored medicinal uses, which aim to restore a person toyou guessed itnormality. Has most of society been afraid not only of party drugs, but also of the experience of awe? Awe is regarded as okay for the occasional mystic, who may even be elevated to sainthood (for example, Francis of Assisi, after whom the current Pope chose to be named), but it arouses suspicion when people talk to birds. Thats weird.

Nobody wants vast criminal syndicates, users do not want the risk of impure drugs (with dangerous molecules sometimes being sold as Ecstasy), nobody wants their children thrown in prison for smoking pot while good burghers drive their cars to a bar to get plastered, nobody wants to pay higher taxes to keep non-violent young people locked up, and researchers do not want prohibitions on research about amazing substances, even if they were not widely used. But anything in defense of normality.

The big question is whether were ever going to find a way to integrate awe into lives that are otherwise normal, to tolerate a regime under which people can, if they want, suspend ordinary reality in a safe and beneficial way. At least since 1954, when Aldous Huxleys Doors of Perception gave us that brilliant writers account of his trip on a classic psychedelic, explorers have tried to bridge the gap between their direct experience and the views of the majority who werent burdened by personal encounters with awe but who, with the help of the media, knew what they believed.

Huxleys spirit was put in a religious context by Huston Smith, who spoke of cleansing those Blakeian doors.

More recently, people who feel that a therapeutic trip has been one of the most important experiences of their lifetime or have found mega benefits in micro-dosing have adopted various rhetorical strategies to try to communicate their discovery. Im reminded of this attempt, which has now continued for a half century or so, by two recent books, The Psychedelic Renaissance (2012) by Ben Sessa, and A Really Good Day (2017) by Ayelet Waldman.

An English physician and researcher, Sessa adopts the strategy of identifying with his profession and searching for ways that classic psychedelics (and MDMA) can help psychiatrists reduce unnecessary suffering. At the same time, he wonders aloud why, after scorning hippies, he has adopted many of their values and insights. Then he returns to the sobriety of his status in society, his caseload, and research based on double-blind evidence.

Waldman adopts a different strategy. Professionally, she is a writer. She is also a mother of four. She suffers from depression and anxiety. She had heard that taking a tenth of a normal dose of LSD might help. She followed a protocol described by Jim Fadiman, who began researching psychedelics as a graduate student when LSD-25 was still legal. This accounts for Waldmans subtitle: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life.

Assured of a supply for a month of three-day cycles, Waldman supposedly wonders whether even a micro-dose will kill her or, if not, drive her crazy, with ghastly flashbacks. Despite having been a volunteer for the Drug Policy Alliance, which works against the war on drugs, and in spite of teaching a law school course in the area, Waldman says she started her personal experiment with fear-based stories widely held in our society, inculcated by the misinformation our government has propagated for decades. She then educates her readers with the quite different facts.

So these are the first two rhetorical strategies: identify with your audience (I thought so, too, but boy, was I mistaken) or identify with a valued profession (Im a doctor, I just want to find medicines that work).

One way to make drugs almost acceptable is to present them as potential medicines, under the control of a highly regarded corps of professionals. Can they treat PTSD, as in the studies of MDMA as an adjunct to therapy, studies conducted by the Mithoefers? Can they ease end-of-life fear, as in the project run by Charles Grob? Can they deal with addiction to alcohol and other legal drugs open to abuse?

Another strategy is to argue that, under the Constitution, liberty includes the right to alter, at least temporarily, ones own consciousness: you may not have the freedom to encourage or guide others, but an individual in our society does retain the power to decide what to put in his or her own body, especially if its been shown to be safer than substances sold and imbibed freely.

We have Jim Fadiman to thank not only for Ayelet Waldmans experiment but also for other effects of his own book, The Psychedelic Explorers Guide: Safe, Therapeutic and Sacred Journeys (2011). In contrast to my student reporting on unknown drugs handed around at a frat party, Fadiman describes how to do it right. Experienced people advise: (a) ingest a psychedelic only if you are mentally balanced, (b) get pure substances, (c) take a correct dose, (d) form a positive intention for the trip (and then be willing to let go of it), (e) find and stay in a welcoming non-clinical setting, (f) have an experienced and non-intrusive guide, (g) lie down or find a comfortable chair, (h) listen to music instead of operating machinery or communicating with people outside the room. Of course, prohibition makes it difficult to get pure substances, and current law would make any guide an accessory.

Another rhetorical strategy was inherent in the 1960s project on psychedelics and creativity led by Professor Willis Harman. This project gave a classic psychedelic to professionals who were working with resistant challenges in their fields. It discovered benefits before the project was cut off when the government decided to make LSD illegal. That was in 1968 (the same year Martin Luther King, Jr., was shot, Bobby Kennedy won the California primary and was then assassinated, and Richard Nixon nabbed the Presidency).

If creativity is not enough to win approval, how about a hypothesis about evolution of the species, that it was psilocybin that helped convert primates into archaic humans? Along with many other speculations in the course of his career, Terence McKenna explored this possibility around 1992. What was his motive? If we could import into straight society, almost as a Trojan horse, the idea that these psychedelic compounds and plants are the catalyst that called forth humanness out of animal nature, if we could entertain this as a possibility, he said, it would alter societys efforts to control and eradicate these substances.

In contrast to proposing bold but unprovable theories, recent researchers looked at neurological data, gathered in large part by methods not yet available when classic psychedelics became widespread in the U.S. For example, Robin Carhart-Harris at Imperial College in London used magnetic resonance imagining to map effects in the brain.

Data about spiritual experience was reported in research led by Professor Roland Griffiths at Johns Hopkins, as expressed in the classic paper, Psilocybin occasioned mystical-type experiences The investigators focused not on an illness that was to be alleviated but rather on an enhancement of ordinary life.

To summarize the rhetorical strategies cited here:

There are other rhetorical strategies, but these are enough to illustrate the persistence and ingenuity of people who are still seeking, after a half century of prohibition, to bridge the gap between firm beliefs of the general public and data developed, against official resistance, by research both here and abroad.

When fear is aroused, as in the war on terror, good public policy is swept aside and we tend not to look at facts.

In the case of psychedelics, what will work? We are encouraged to be patient, as was Martin Luther King, Jr., by white colleagues at the time of the Montgomery demonstrations. In response, King asked whether the time since the Civil War was long enough to wait.

The prohibition against psychedelics has lasted about half a century. Critics of the fear-response decry the losses: the healing that has been lost, the abuse of liberty, the loss of research, of creativity, of experiences of awe.

One of the U.S. organizations that has worked persistently and ingeniously during most of this period of prohibition has been the Multidisciplinary Association for Psychedelic Studies (MAPS), founded by Rick Doblin, a graduate of Harvards Kennedy School. MAPS has held conferences on psychedelic science, sponsored research here and abroad, published a newsletter, and tried to educate the political establishment.

Other leading organizations include the Heffter Research Institute, which gathered key academics in this field, Amanda Feildings Beckley Foundation in the U.K., Bob Jesses Council for Spiritual Practices, the archives at Purdue University (Psychoactive Substances Research Collection), and the Vaults of Erowid.

On the model of cannabis, perhaps it would be helpful to establish medical uses, then move on to what is called recreational use, a term that refers to all uses not controlled solely by physicians but freely available to the public. The term recreational is prejudicial like the term drugs, which fails to distinguish between classic psychedelics and addictive or otherwise harmful drugs, such as heroin.

For example, there is nothing recreational about the experience of awe or of wonder. The term trivializes what can happen. Drugs are taken not only to get high or cure a health condition, but also to take a holiday from the confines of ordinary reality, as in studying a textbook, buying a house, raising children, serving as a professional, and so forth. What if, instead of an ill-conceived and unworkable prohibition, we focused our ingenuity on making the opportunity for good trips part of a normal life?

One pioneer who sketched this possibility was Gordon Wasson, a U.S. banker who made a famous trip to a tribal area of Mexico and experienced a psilocybin mushroom ceremony with a local shaman, and wrote about it in Life magazine (in1957, a few years after Huxleys book). What was his first reaction after the mushroom took effect? I felt awestruck.

Later he co-authored a book, The Road to Eleusis (1978), working with Albert Hofmann, the Swiss chemist who synthesized and then, in 1943, discovered the mental effects of LSD, and with a professor of classics named Carl Ruck. They proposed that the ancient ceremony at Eleusis included a psychedelic. (No one knows for sure because the participants were sworn to secrecy.) The point is, the ritual was not counter-cultural but part of the culture, not for everybody, but not considered a challenge to the dominant way of life.

Perhaps our culture will accept the value of psychedelics through demonstrations of their usefulness in alleviating suffering, through medical applications. But it was observers such as Wasson who understood that their most extraordinary value was experiencing awe and that this opportunity could become part of a normal life.

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Reasons to Consider Trying Psychedelics – FoxWeekly

Posted: July 25, 2017 at 12:28 pm


FoxWeekly
Reasons to Consider Trying Psychedelics
FoxWeekly
The word psychedelic roughly translates to mind revealing. It is derived from the Greek words psyche and deloun. It is a term used to refer to any phenomena that alters a man's state of consciousness, cognition or perception. The psychedelics we ...

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Psychedelic Shine takes a trip to the skies in Boulder – Boulder Daily Camera

Posted: July 22, 2017 at 8:21 am

If you go

What: Psychedelic Shine: Extended-State DMT with Dr. Andrew Gallimore and

Breathwork

When: 2 to 9:30 p.m. Sunday

Where: Shine Restaurant and Gathering Place, 2027 13th St., Boulder

Cost: $20 to $55 (various packages)

More info: medicinalmindfulness.org/psychedelic-shine

The world may owe psychedelics a little credit.

George Harrison, citing LSD as a necessary experimentation for the Beatles in the '60s, told Rolling Stone, "It was like gaining hundreds of years of experience in 12 hours."

Francis Crick, the co-discoverer of the DNA molecule structure, was allegedly on LSD when he lightbulbed the idea of the helix structure.

And Steve Jobs kept it no secret that he experimented with LSD in college. Apple's late-cofounder told his biographer, Walter Isaacson, that "taking LSD was a profound experience, one of the most important things in my life."

Coming to Boulder from Japan on Sunday, neurobiologist Dr. Andrew Gallimore will discuss how the psychedelic drug, DMT, can be used as a tool for exploring alien worlds.

DMT (N,N-Dimethyltryptamine, for the science types) is a molecule naturally produced in various plants, animals and humans. The well-known version of DMT, ayahuasca, is a tropical Amazonian vine, known for its hallucinogenic properties and is often made into a tea, which is experiencing a boom in the United States with ceremonies from Brooklyn to Silicon Valley. (Marc Maron recently said on a "WTF" podcast that DMT is so trendy right now. His guest Susan Sarandon agreed, explaining her trip on ayahuasca.)

Medicinal Mindfulness, a consciousness company in Boulder, is hosting the Psychedelic Shine event that also features live music and breathwork exercises (to help achieve deep healing from anxiety or trauma) from 2 to 9 p.m. Sunday at Shine Restaurant and Gathering Place, 2027 13th St., Boulder.

But back to that mind-altering mecca.

"I see DMT as a tool for accessing alternate realities and establishing stable communication with intelligent beings not of this world, not even of this universe," Gallimore said via email from a conference in Belgium. "The verification that such intelligences exist and that we could communicate with them would, in my opinion, the most profound discovery in the history of mankind."

Dr. Andrew Gallimore explains the brain on DMT

The world you experience, whether during normal waking life, dreaming or at the peak of a DMT trip, is built from information generated by the brain. This world is a model and should not be taken as the definitive absolute reality. The brain has evolved to build a world for you to live in, a world that is a useful model, but "truth" has nothing to do with it. It is a mistake to assume that the normal waking world is the "real thing" and any alternative worlds are mere hallucinations or false perceptions. The waking consensus world is a functional model, a simulacrum in which to survive and reproduce.

When you drift into the dream world at night, your brain builds your world in almost exactly the same way as it does during waking. The only difference is that, during waking, the information used to build the world is modulated by a relatively small amount of information from the senses.

The world is merely constrained by sensory information, but not built from it your world is always built from information generated by your brain. When a psychedelic drug, such as LSD, enters the brain, it interacts with specific receptor proteins in the cortex. This changes the patterns of information generated by the brain and, since your world is built from this information, your world changes. The world shifts from being stable and predicable, to unstable, unpredictable and novel. However, DMT has a much more profound effect on the brain and seems to activate a complete reality switch the information generated by the brain no longer manifests as the world we are familiar with, but an entirely new world of astonishing complexity and strangeness: a hyperdimensional alien reality replete with hyperintelligent entities.

Why DMT, the most common natural hallucinogen in the world, has this special ability to flick the reality switch in this way is open to speculation. I speculate in one of my papers that DMT might have been implanted as a message about the nature of our reality by an advanced intelligence a message that can only be decoded once humans reach a degree of cognitive sophistication to identify and isolate DMT from the plants in which it occurs. But this is highly speculative and not necessarily something I believe.

Gallimore, based in Japan at the Okinawa Institute of Science and Technology, explained that the world we experience whether it's waking life, dreaming or at the peak of a DMT trip is built from information generated by the brain. In short, some psychedelics, such as LSD, interact with receptor proteins in the cortex, changing the patterns of information generated by the brain, he said. DMT, on the other hand, has a much more profound effect on the brain.

"(It) seems to activate a complete reality switch," said Gallimore. "The information generated by the brain no longer manifests as the world we are familiar with, but an entirely new world of astonishing complexity and strangeness: a hyperdimensional alien reality replete with hyperintelligent entities."

Is it a big drug party at Shine on Sunday, then?

No. There will be no consumption of any drugs, Medicinal Mindfulness Executive Director Daniel McQueen said. This is the 10th Psychedelic Shine (the February event at the Boulder Theater gathered 500), and this particular one is "going to be a wild one," said McQueen, a spirituality and life coach.

"It's the most controversial topic we've explored so far and we expect to fill the place," said McQueen. Medicinal Mindfulness will be filming a documentary for Gaia TV, a streaming service based out of Louisville with programing that focuses on mind, body and spirit.

McQueen called the event part "grassroots consciousness experience," and will be speaking about his research proposal. With a master's degree in transpersonal counseling psychology from Naropa, he said in his practice he works with cannabis as a tool to initiate healing transformations.

"I haven't experienced anything more effective in healing," he said. "We work with medicines in an intentional way by going into unconscious behavior to help with revealing, healing and inspiring the person."

McQueen said he has also studied the effects of MDMA (ecstasy, molly) on post-traumatic stress disorder patients in approved research settings.

"Psychedelics allow us to look at something deep within, whether it's a problem or struggle or a pattern we are unconscious about that's not healthy," he said. "A combination of the medicine and solid psychotherapy allows the person to review traumatic material without being re-traumatized by the events."

McQueen explained that psychedelics, which are reported to increase empathy and euphoria in users, can help the patient look at their problems in a compassionate and non-judgemental way.

"Once you come out of the experience after the healing, many patients find it difficult to revert back to living the way they did before because the conscious mind knows it wasn't having a positive impact," he said. "We call it integrating the lessons and understandings of how to move forward with life."

McQueen said, like any therapy, the journey is an ongoing one. He said the practice helped him to heal from his own past trauma and to step into the person he truly is now. Along the way, he said he has seen many other transformations.

If DMT is so extraordinary and a naturally-occurring, nonetheless, psychedelic substance, how can the world play without legal access since it's classified as a Schedule I drug?

"We're seeing a renaissance of psychedelic research since the several decade-long hiatus because of prohibition," said Gallimore. "Now we're seeing an increasing number of research programmes (sic) looking at the mechanisms of psychedelic drug action in the brain, as well as exploring therapeutic uses. However, I don't see any time in the near future when DMT will be freely available for the purpose of communicating with extradimensional intelligences. That's just too far out. But one day perhaps."

Gallimore wouldn't divulge his DMT channel of choice, but said he has been to extra-dimensional realities "a number of times."

Is it like spaceships and purple beings with buggy eyes?

"For me the place is always similar, one of extreme complexity and with a technological ambience, as if this place has been there for countless trillions of years before our universe popped into existence," Gallimore said. "The power and intelligence of the beings that reside therein is overwhelming, the point we might expect an intelligence to reach after trillions of years of evolution."

McQueen and Gallimore said they encounter skeptics many of whom have never taken DMT before.

"To gain a deep understanding of what we do, someone should try it to experience it in context, read about it and learn about the clinical support for what we do," said McQueen.

"It's just a hallucination" is the usual response. Many think it's a recreational substance only for use at parties or raves.

But there's a simple answer for the skeptics.

"I always say the only true convincer is a small glass pipe and somewhere comfortable to lie down for 20 minutes," said Gallimore.

Have a nice trip.

Christy Fantz: 303-473-1107, fantz@dailycamera.com or twitter.com/fantzypants

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Psychedelic drugs could tackle depression in a way that antidepressants can’t – INSIDER

Posted: at 8:21 am

Jul. 20, 2017, 12:16 PM

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When Clark Martin tripped on magic mushrooms for the first time, he was flanked by two researchers in a small room at New York University.

An avid sailor, Martin said the first few hours of the experience reminded him of a time he'd been knocked off his boat by a powerful wave and lost track of the vessel.

"It was like falling off the boat in the open ocean, looking back, and the boat is gone. Then the water disappears. Then you disappear," he said.

But the panic was temporary. Over the next few hours, Martin felt overwhelmed by an enduring sense of tranquility and a feeling of oneness with his surroundings.

"The whole 'you' thing just kinda drops out into a more timeless, more formless presence," Martin told Business Insider in January.

That shrinking of the sense of self has been linked with long-lasting shifts in perspective changes that appear to be related to a reduction in symptoms of depression and anxiety. That's according to clinical trials of magic mushrooms' active ingredient, psilocybin, in cancer patients at Johns Hopkins and New York University. Martin was one of those patients.

David Nutt, the director of the neuropsychopharmacology unit in the division of brain sciences at Imperial College London, told Business Insider in January that a key characteristic of mental illnesses like anxiety, depression, and addiction is overly strengthened connections in some brain circuits specifically those involved in the sense of self.

"In the depressed brain, in the addicted brain, in the obsessed brain, it gets locked into a pattern of thinking or processing that's driven by the frontal, the control center," Nutt said.

Brain scan studies and several clinical trials suggest that psychedelic drugs tamp down on the activity in these circuits, potentially providing relief that may last a few weeks, several months, or even years. For this reason, preliminary research on psychedelics suggests they could one day be used to help treat mental illnesses.

"Psychedelics disrupt that process so people can escape," Nutt said. "At least for the duration of the trip, they can escape about the ruminations about depression or alcohol or obsessions. And then they do not necessarily go back."

Researchers say the drugs' apparent ability to induce powerful, positive changes in personality could offer a way to address the foundations of mental illness, unlike current antidepressant medications that simply treat the symptoms.

"Psychedelic therapy ... offers an opportunity to dig down and get to the heart of the problems that drive long-term mental illness in a much more effective way than our current model, which is take daily medications to mask symptoms," psychiatrist Ben Sessa said at a recent conference in London on the science of psychedelics.

The drugs are not a treatment in and of themselves, Sessa said. Rather, they are a tool that can be used in conjunction with therapy to help people address underlying issues.

"It's using the drugs to enhance that relationship between the therapist and the patient," he said.

Julie Holland, a psychiatrist who is currently serving as the medical monitor for a study of MDMA and psychotherapy in veterans with PTSD, said at the conference that she sees the use of psychedelics alongside therapy as a powerful way to address issues that patients may never deal with on existing anti-depressant medications.

Those medications, Holland said, "are sort of sweeping symptoms under the rug. Psychedelic psychotherapy takes the rug out back and beats the hell out of it and vacuums the floor and puts the rug back down."

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Do You Take Drugs at Festivals? This Initiative is Working on Keeping You Safe – PoliticalCritique.org

Posted: July 20, 2017 at 3:22 am

Despite its popularity, recreational drug use remains stigmatised. Thus, it can be difficult to find reliable information, and if you do end up on a bad trip, specialised help and emergency rooms at festivals are not only few and far between, but users might also feel discouraged from seeking help for fear of being reported to the authorities.

The Czech Psychedelic Society is working to change that. Their PsyCare initiative is a cozy and safe tent, where users can get information about drugs, as well as be helped through a bad experience. Qualified volunteers accompany the visitors for hours, making sure they feel comfortable PsyCare is thus an important program of on-site harm reduction. You can support the crowdfunding campaign here.

Anna Azarova: In your experience, is drug consumption common at the festivals you work at? Svatava Bardynov: Yes, definitely. The international experience is that roughly 1% of festivalgoers visit PsyCare tents. But at a festival where we worked last month, we had more than 20 out of 100-300 guests around 20%.

Festivals are required to have on-site paramedics at all time, and many people dont see the point of harm reduction or drug sitting tents. How is your work with PsyCare any different? The biggest difference, Id say, is that we dont judge people for taking drugs: we know that its very common to take them, especially recreationally. When people have a bad trip, they can have difficult psychedelic experiences, and the paramedics cant really help them properly, because, as we see it, their needs are more psychological, and they often see it differently. But we can approach it from this point of view as well.

So if someone is, lets say, on acid and isnt feeling very well, and goes to the ambulance, they really dont know what to do. Sometimes they give them diazepam or some other benzodiazepines. Thats often not very helpful: you can calm people down a bit, but at the same time, the psychological aspect of the trip is prevented from ending on its own terms.

Some people have stayed with us for 6 hours, and our volunteers are with them throughout the whole time.

The way we see it, is that in this state people need a safe environment and education. The volunteers working with us are all experienced with psychedelics; and we all work as psychiatrists or social workers with drug users, so we know both the counselling and the preventative sides of the work. We can really help them to go through the psychedelic experience in comfort and safety to do what they need, be it crying or screaming, or simply just lying down, or even closing their eyes if they want to but often talking, or being close to others is very helpful in itself. We can stay with them and support them for hours some people have stayed with us for 6 hours, and our volunteers are with them throughout the whole time. With psychedelics, it is very important to finish the trip so there is no unresolved residual issues. If you prevent the psychedelic high from resolving on its own, you risk having psychiatric issues, such as flashbacks, in the future. In a way, PsyCare is focusing on prevention to avoid those issues. Paramedics are not prepared to do this work.

What are you snorting tonight? Meow meow? Yeah, sure.

What is it about the festival environment that can trigger a bad trip? Does it happen often? Its difficult to say how often it happens, and there are many factors that can influence the experience, whether it be a bad trip or not. Some people are more sensitive to psychedelics, and of course it also depends on the dose. And, thirdly, your experience: most people who have a bad trip are first-time users.

Festivals can be a risky environment for taking psychedelics, especially if youre inexperienced.

Furthermore, festival settings can be quite overwhelming: you have to remember not to lose your wallet or phone, your friends are coming and going, its chaotic, and the music is often very loud. And of course, there are also other drugs, which visitors combine with the psychedelics the combination with alcohol is especially risky. After the psychedelic experience, you should also be able to take some time off to rest which can be difficult with everything around you being chaotic. I wouldnt say that its all crazy at festivals, but it can be risky, especially if youre inexperienced.

Apart from helping people through their bad trips, is there anything you are currently unable to do, but would want to? The biggest limit in PsyCare work is that the whole process is improvised. When people come to our tent, theyre already under the influence, and it can be hard to make agreements with them, for example that they dont take any other drugs.

Apart from that, it would be great to be able to provide drug testing, but at the moment we cant: it is very expensive, and we dont receive any funding.

Machon: Prohibiting a Little Weed? What Damage It Did!

The Czech Republic has the reputation of being one of the most liberal states in Europe concerning drugs. Is the legislation on psychedelics different from more widespread drugs, such as marijuana or MDMA? Psychedelics are considered to be hard drugs in the Czech Republic, and are illegal. Even though we have a lot of mushrooms growing in every forest, if you pick them and run into a police officer, you can get into a lot of trouble. On the other hand, drug use is very wide-spread in the Czech Republic: we are among the biggest consumers of cannabis, MDMA, and methamphetamine in Europe.

Under this legislation, to what extent is harm reduction work possible? What is also impossible, but should be possible? Its mostly alright we are allowed to do our work. But now it is mainly a question of money: it would be great if we could raise enough to pay at least the coordinators, if not all the volunteers.

It would be great if we could provide drug testing, but (since we work here on voluntary basis) it is a lot of work to write and apply for governmental grants; and the chances of receiving money for this kind of project is incredibly low. Ideally, we would be able raise enough money independently to use for both the testing and the PsyCare projects.

Currently, there are no organisations doing drug tests in the country. There used to be some a couple of years ago, until theNational Monitoring Centre for Drugs and Addiction forbade independent organisations from doing it. Through this organisation, the government could exert pressure on the NGOs so that they could receive no funding at all if they engaged in drug testing so they stopped.

But if we would be able to stay completely independent from the state, we could start offering it again.

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Should We Reclassify Marijuana as a Hallucinogen? – Big Think

Posted: at 3:22 am

Marijuana has been hard to classify, historically. It doesnt fall neatly into any of the other categories, be they stimulants, depressants, opioids, or what-have-you. As a result, its be dropped into a slot all its own. At a recent psychedelics conference in London, New York psychologist Julie Holland suggested a recategorization for cannabis, as a hallucinogen.

Her reasoning, it can cause "dehabituation," or the ability to see an issue from a completely new perspective. According to Holland, "The thing that I'm interested in with cannabis is how it does this thing where everything old is new again." Such an experience is very therapeutic. Consider being able to suddenly see a traumatic memory differently, and to frame it in a healthier way.

Currently, not much is known about marijuanas effect on the brain. Some research shows that chronic use can increase the risk of psychosis. Psychosis however, is defined in a very specific way. Its considered either becoming overly paranoid or experiencing hallucinations.

Marijuanas inducement of dehabituation may be useful for clinical purposes. Getty Images.

Some research suggests that chronic marijuana use doesnt cause psychotic disorders, but may be a catalyst to an episode thats already developing. In other words, its those who suffer from mental illness who gravitate toward chronic marijuana use, perhaps to self-soothe. But theyre also barreling toward an episode.

So how would dehabituation work therapeutically? In this case, a therapist would have a patient use marijuana and then take them on a guided trance, in such a way as to install a healthier viewpoint in them. Could such a thing be done?

Some fear marijuana use alongside psychological treatment could trigger a mood disorder such as anxiety or depression. But a well-regarded study recently upended such claims. It may cause problems in the developing brain however, particularly in those between adolescence and age 25. There are conflicting views. If it were cleared, cannabis therapy would have to be performed only on those over a certain age.

Marijuanas psychoactive ingredient, delta9-tetrahydrocannabinol (THC), can cause neural noise. This is experiencing a stream of random, unrelated thoughts, or even a hallucination. The person feels the effect of neurons becoming overactive inside their brain. These electrical disturbances, in marijuanas case, calm down quickly. Over the course of some minutes, the patient enters an altered state, losing touch with reality and then returns. Most psychedelics meanwhile, last for hours.

Chronic marijuana use may be detrimental to those under age 25. Getty Images.

According to Dr. Holland, "In psychiatry it seems that cannabis is grossly underused and understudied." Most marijuana studies have looked at it as a way of alleviating the side effects of say cancer treatment or severe epileptic disorders, offering pain relief, dampening Parkinsons, and mitigating the symptoms of other serious illnesses. Few have looked at it for mental health treatment. Some of those studies do show that it may be helpful for treating PTSD, anxiety, or depression.

Meanwhile, a growing body of evidence shows that psychedelics can be useful in overcoming psychological disorders. Research has found that LSD can help addicts and alcoholics overcome addiction. Psilocybin, the active ingredient in magic mushrooms, was shown to helpcancer patients overcome depression and anxiety.Meanwhile, MDMA has successfully treated PTSD.

As a result of these and other findings, medical research on psychedelics has increased in the last 15 years or so. Even so in the US, marijuana and most hallucinogens are considered schedule 1 narcotics under the federal Controlled Substances Act. Therefore, research on such drugs has been limited. Gaining approval from multiple federal agencies is required, to study either one, which can take years. Even so, interest in using both marijuana and hallucinogens for therapeutic purposes is growing.

Marijuana and psychedelics like LSD and psilocybin, may interact differently within the brain, discouraging reclassification. Studies using the brain scans of patients on psychedelics show that their brains make new connections with disparate parts. Different regions may interact with the visual cortex for example, allowing those on acid to smell colors or visualize music. No such equivalent has been witnessed in marijuana users.

Chronic use of marijuana effects the orbitofrontal cortex, the nucleus accumbens, and the amygdala. The first has to do with decision-making and information processing, while the second and third are both part of the brains reward circuit. The amygdala is also the center for our emotions.

Psilocybin mushrooms. Getty Images.

Could neural noise and the experience of dehabituation, no matter how brief, lead to marijuanas reclassification? Probably not. It would be of little value, since theyre both are at the same classification level. Would there be any other advantages in seeing marijuana reclassified?

Not really. What a growing number of researchers, policy makers, and journalists are saying, is that there needs to be a change in the classification of both marijuana and hallucinogens in the US, on the federal level. These drugs arent deadly, have no long-lasting side effects, and arent physically addictive.

A rescheduling would allow for more research, so we can better understand how they affect human health, and if these drugs can be leveraged effectively for clinical purposes, with minimal side effects. Despite obstacles, Holland and colleagues are working on a study which will assess whether or not marijuana helps reduce PTSD symptoms. Veterans have been claiming it does since the Vietnam War era.

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Countdown To (Legalized) Ecstasy! Rick Doblin, MAPS, & the Psychedelic Renaissance [Podcast] – Reason (blog)

Posted: at 3:22 am

Reason.com"The experiences I've had with psychedelic drugs, namely psilocybin, MDMA, and LSD, but particularly MDMA, have been personally transformative for me," says Mike Riggs, a reporter for Reason and the author of a blockbuster new story about how medical and psychiatric researchers are using psychedelics to help their patients. "Not frequent use, but kind of taking these drugs and then having really intense, in-depth, long conversations with intelligent people about how to get better, just how to get better as a person, as a human being, how to be a better neighbor, how to be a better friend."

It was that experience that led Riggs to study groups such as The Multidisciplinary Association for Psychedelic Studies (MAPS) and its founder, Rick Doblin. "Doblin is a totally fascinating guy," Riggs tells me in the newest Reason Podcast. "He started MAPS in 1986. His journey of studying and advocating for the use of psychedelic drugs in therapeutic settings began in the late 1960s or early '70s. He was kind of a guy who, for a long time starting when he was in college all the way to the mid-'80s, he was a guy who's like, 'We can get this to where it needs to be in terms of legitimacy simply by talking about it and simply by doing it.' And so in the 1960s and 1970s, there's some underground psychedelic therapy work in which psychiatrists who either participated in the research in the 1950s with LSD continued secretly. And then going into the 1970s when MDMA was kind of rediscovered by this chemist named Sasha Shulgin. MDMA wasn't illegal. It hadn't been banned. So psychiatrists were able to use it as kind of a research chemical."

The tale Riggs tells isn't one of wanton hedonism or Dr. Strange-level trips. Rather, it's one in which doctors and patients are working together against the backdrop of a decades-long war on drugs to figure out new and effective ways to treat PTSD, depression, and other maladies with currently illegal substances. And more amazing, how Doblin and crew are on the verge of changing the way that the government regulates drugs.

Produced by Ian Keyser.

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This is a rush transcriptcheck all quotes against the audio for accuracy.

Nick Gillespie: Hi. I'm Nick Gillespie and this is the Reason podcast. Please subscribe to us at iTunes, and rate and review us while you're there.

Today, we are talking with Mike Riggs. He's a reporter for Reason. He writes for the magazine, the print magazine. He writes for the website. And he occasionally appears in videos at Reason TV. Mike, thanks so much for talking to us.

Mike Riggs: Yeah. It's my pleasure.

Gillespie: All right. So, you've got a kind of blockbuster story coming out, or out at Reason.com, which is about how after 30, 40 years, 50 years, almost 60 years, psychedelic drugs are being taken seriously by all kinds of medical researchers, psychological researchers, et cetera. Explain, briefly, what the thesis of your story is.

Riggs: The thesis of the story, I would say, is basically that while most people who follow drug policy reform kind of broadly or generally think of it as using ballot initiatives for drugs like marijuana to basically kind of legalize through mobilizing the citizenry that there's an entire alternative path that's being pursued by psychedelic researchers. People who are studying the medical applications for LSD, psilocybine, MDMA, and some other drugs like that. Their path, they have never tried the referendum approach. They've never tried getting legislatures to pass laws to decriminalize or legalize these drugs. The trajectory they chose was instead to go through the FDA. Let's jumped through all the hoops. Let's dot all the I's, cross all the T's, and that's all the trials necessary to have the FDA approve these substances as pharmaceutical drugs. The benefit of this is that it basically removes democratic politics from the drug approval process-

Gillespie: And democratic, small d there, right? I mean, you don't have to-

Riggs: Yeah, yeah.

Gillespie: You don't have to get 50% plus one or two thirds or anything like that. What you are doing is you're going to the gate keeper institution that says, "Here are good drugs that pharmaceutical companies and doctors will create, and doctors will prescribe. You'll pay a co-pay, et cetera." As opposed to basically the model for medical marijuana and recreational marijuana, increasingly.

Riggs: Yeah. And so, the plus side is you don't have to worry about a legislature sabotaging this or having some kind of campaign finance war where it's who can spend the most on advertising. The downside is that it happens much more slowly. California passed it's first medical marijuana law in 1996. We're just shy of 20 years later and marijuana, is across the country, revolutionized. Meanwhile, the process that psychedelic researchers have gone through, started in about 1986. It's now 2017. None of these drugs are yet legal.

Gillespie: What is the status? I mean, the drugs in America are put, since the Nixon years, they're put on different schedules including a schedule one drug, which it's got a high potential for abuse and no known medical use, right?

Riggs: Yeah, that's true.

Gillespie: Where is LSD, psilocybin, Ecstasy or MDMA, and the like? Because what's interesting about these and LSD is obviously, or not obviously, but probably the most famous, but that drug was legal until 1966. Ecstasy was legal until 1986. Are any of these drugs, are they in something other than schedule one?

Riggs: No, they're all in schedule one. But the one exception is ketamine, which I think is on schedule two or schedule three. And that's only because it was used for a very long time as a surgical anesthetic before anybody realized that it had dissociative properties, which dissociation kind of fits under the umbrella or psychedelic side effects, though it's not really a psychedelic drug. But everything else is in schedule one.

Gillespie: Walk us through. What is LSD good for besides just tripping your balls out?

Riggs: The argument, and this argument was made a long time ago, Aldous Huxley in "Doors of Perception and Heaven and Hell," wrote about LSD. Albert Hoffman, who was the chemist at Sandoz Pharmaceuticals who studied LSD. Basically, going back to the '40s and '50s and '60s, the argument has been that psychedelic drugs, and the first one that anybody really tried was the LSD, kind of stops you from being who you are for long enough for you to change who you are. As an adjunct to psychotherapy, if you're working with someone who's seeing a lot of people taking LSD and worked with a lot of people who've taken LSD, this is not actually as scary as it sounds. If you're somebody who has a substance use disorder or you're a binge eater or you're depressed or you're anxious or you're-

Gillespie: And an alcoholic, right?

Riggs: Whatever you want to say.

Gillespie: Yeah.

Riggs: Yeah. That was the first one, that was the big one was alcoholics, was the idea that there was something underneath the alcoholism, that there was some sort of psychological issue that if you could just sort of pause a person and say, "Let's start from scratch." Again, there's really no other drug or really any other medical therapy or modality that says, "Let's just make you somebody else."

Gillespie: Right.

Riggs: That's kind of what the psychedelic model is.

Gillespie: And then, what about psilocybin and ecstasy? Why are medical researchers or and what's interesting, you went to the MAPS conference. Rick Doblin, the kind of grand poobah of MAPS. These are not people who are, they're not silly people, they're not superficial people. They're talking about how do individuals use drugs like we all use other training regimens or diet or whatever, meditation, courses in education to better ourselves or to understand ourselves better. That's what these people are about. What about psilocybin and ecstasy? What do those do for people in a therapeutic setting?Riggs: If we can just leave the chemistry aside a little bit because it's kind of complicated for both drugs, but at a basic level, psilocybin and MDMA are both being used in patient populations that are experiencing anxiety related to a traumatic experience. For a lot of the studies with psilocybin, they've been used in patient populations that either have a terminal illness or a life threatening illness. In a lot of cases, that's cancer of some sort.

And then for MDMA, it's a lot of the clinical trials involve people who have PTSD as a result of military service or sexual abuse. The basic idea's that while on these substances the patient is just able to confront difficult concepts, difficult memories, without re-experiencing the panic and anxiety and lockdown that they feel when they re-visit those memories when their sober. This is one of the idea of triggering for people with PTSD is that whenever they're confronted by something that resembles this really traumatic experience, you hear about people coming back from Afghanistan or Iraq who hear a car backfire, a door slammed really loudly, and suddenly they're back in Fallujah.

MDMA allows them to sort of re-visit these really hard memories and talk about them and think about them and create a demarcation, maybe a wall, a compartment, where that memory, they're able to disconnect it from this sort of unintentional feedback loop of emotions where every time that memory is evoked, they then have to experience panic or anxiety or fear. And so they can consider the memory, they can be reminded of that experience without feeling all this other stuff.

Gillespie: Well, talk a little bit about MAPS and Rick Doblin.

Riggs: Yeah, so Doblin is a totally fascinating guy. He started MAPS in 1986. His journey of studying and advocating for the use of psychedelic drugs in therapeutic settings began in the late 1960s or early '70s. He was kind of a guy who, for a long time starting when he was in college all the way to the mid-'80s, he was a guy who's like, "We can get this to where it needs to be in terms of legitimacy simply by talking about it and simply by doing it." And so in the 1960s and 1970s, there's some underground psychedelic therapy work in which psychiatrists who either participated in the research in the 1950s with LSD continued secretly. And then going into the 1970s when MDMA was kind of re-discovered by this chemist named Sasha Shulgin. MDMA wasn't illegal. It hadn't been banned. So psychiatrists were able to use it as kind of a research chemical.

Doblin had met all these people. He'd heard great stories about therapists working with these drugs. He said, "This should be enough. We've got all these M.D.s, a lot of them affiliated with academic institutions. A lot of them have been in practice for a long time. They have great medical records. They haven't been sued out of existence. They haven't had their licenses revoked. This should be enough to get the government to recognize these as therapeutic drugs."

As we know, most every therapeutic drug that also happens to make people feel good, MDMA worked it's way into the recreational community the same way that LSD had and other drugs like that. And so, when the DEA decided to crack down on MDMA in the 1980s, the evidence that all these psychiatrists put forward and that Doblin helped organize and deliver to Washington D.C. really didn't move the needle. The DEA engaged in years long battle with all these therapists throughout the 1980s and by the late 1980s had won the battle. And so, these drugs were added to schedule one.

Gillespie: One of the things that is fascinating about ecstasy or MDMA, excuse me, is and I say this as somebody, I was in college from '81 to '85, ecstasy was free and legal, or it wasn't free, but it was very cheap and it was legal. But it was seen as an anti-social drug because you would have such intense feelings and emotions. You would just stay in a room with yourself and your girlfriend or boyfriend and touch fingerprints. You wouldn't even go outside because you didn't want to. You were exploring yourself. It was a very introspective drug. Once it was banned, it became the ultimate party drug and the rave drug and then everybody ... One of the reasons it was banned is because it turned people dangerously anti-social. After it was banned, it became the rave drug of choice. Kind of fascinating.

How do the phrases set and setting fit into the broader kind of psychedelic research that you've been covering?

Riggs: Yeah. Set and setting is probably the most significant contribution from Timothy Leary to the contemporary movement. Leary, in the 1960s, was a big advocate of LSD. He worked at Harvard and lost his job because he was giving drugs to undergrads. He coined this idea of set and setting, which is set is mindset. So how you're thinking about a drug or what you're going to do on the drug before you do it. And then setting is the physical setting that you're in. Psychedelic therapists still use this language today. Mindset, you want to prepare a patient for the experience that they're going to have when they're on one of these drugs. And then setting is you want to make sure that they feel safe and comfortable and that there's nothing in their immediate physical environment that's going to upset them.

It's also terminology that's used by recreational users. I mean, there are all kinds of forums on the internet from Bluelight to Reddit where users will say to other users, "Hey. I was thinking about using this psychedelic drug at event X, Y, or Z." And then there will be a conversation about whether or not that's a good set or setting based on how the drug affects the mind. It's very interesting. There's a sort of an element of planning and preparation for psychedelic drugs you generally don't see with things like marijuana or cocaine just because the potential for a really bad experience if you're not thinking ahead and you're not being prepared is so much more real for LSD or psilocybin than it is for marijuana.

Gillespie: Well, then, it's also the trip lasts longer. It's like planning a golf outing or a long horseback ride or something where with cocaine you're not talking about minutes. You're talking about, an LSD trip could last anywhere from 4 to 12 to 24 hours.

Riggs: Yeah. LSD lasts an incredibly long time. MDMA is on the shorter side. It's maybe two hours, two and a half hours. Psilocybin's somewhere between. But yeah, these drugs all last much longer than marijuana and certainly much longer than cocaine, which peaks really quickly and then you hit the trough pretty quickly after that.

Gillespie: What did these guys do to win the FDA over to at least considering rescheduling things or to take seriously the idea that these drugs that have been associated for decades now with hippies and youth and out of control kinds, all of that kind of stuff? How did they get the FDAs attention to say, "Okay. You know what? We want to start thinking about this more seriously."

Riggs: Part of it was sheer, dumb luck. In the late 1980s, the FDA created a new unit within itself that was tasked with expediting the investigational new drug application process, which is where a researcher says, "Hey. I have chemical X or Y. I think it could be useful in this setting. I'd like to move my research from animals to humans." Prior to the late 1980s, there were a lot of those applications would come into the FDA and a lot of them have just been put on hold. This group called the Pilot Drug Evaluation Staff started in the late 1980s to bring some sort of entrepreneurial elements into the FDA, started going through all these old applications and realized that overwhelming amount of applications that had been put on hold were for psychedelic drugs.

Around the time that this division was created, Rick Doblin, again the founder and president of MAPS, met a psychiatrist named Charles Grobe, who still practices today and is a medical school professor in California. Together, they said, "Hey. Let's submit a proposal for FDA to kind of get this process started." So that's what they did. Grobe put together an investigational new drug application with a limited trial for cancer patients suffering anxiety. He and Doblin and some other psychedelic researchers, mostly chemists, flew to Washington D.C. for meetings with all the alphabet agencies, DEA, the drugs [czar's 00:16:09] office, the FDA, Health and Human Services, and basically made their case.

They said, "There's a lot of data out there that wasn't necessarily conducted or gathered through the clinical trial process, but that was gathered by responsible investigators who documented what they were doing showing that we can use this safely in humans. We think we should be allowed to proceed especially if this ends up being a kind of revolutionary new drug for psychiatric disorders." The FDA, after all these meetings with DEA and drug czar's office, the feeling was, "Hey. If this is as tightly controlled, if this process is as by the book as we would request of any pharmaceutical giant, you can go ahead and do it."

So Grobe and Doblin got permission to do so. They raised the money from philanthropists to conduct these studies. That's something else worth noting, that almost none of the psychedelic research is tied to the pharmaceutical industry in any way because all these drugs are off patent. They're all-

Gillespie: Even though all of them, I mean, came out of the, for lack of better term, the legitimate pharmaceutical industry. Right?

Riggs: Yeah, no, that's true. MDMA, LSD were both developed by pharmaceutical companies in the 20th century. Merck developed MDMA right at the turn of the 20th century as a sort of intermediate drug for something else. They never used it in humans. It was never of interest to their clinical team. LSD was kind of the same. But, yeah. The only one that's really got any pharmaceutical company involvement is ketamine, again, because it's not a schedule one, because it was a surgical anesthesia. But, so they just said, "Hey. Let's raise the money. Let's put together these trials."

They kind of bootstrapped it for a little while. I got to talk to a woman at MAPS who defected, for lack of a better word, from Novartis, which is a pharmaceutical giant to go work at MAPS. She talks about how for over a decade, nearly two decades, MAPS did all of their paperwork like an Excel spreadsheet and by hand. They were sort of documented all this way using photocopies and stuff like that. She kind of upgraded them to the more modern pharmaceutical style electronic and digital databases and that kind of thing. But they just tried to do what any other drug researcher working with a budget 100 times larger than their own would do.

Gillespie: Is there interest in pharmaceutical companies to start purveying newer versions, newer and better versions, time release versions? All of that kind of stuff of these drugs.

Riggs: For ketamine, there is right now, again because they know it's legal right now. If you're able to come up with a newer or better version of ketamine, you're time window for getting that approved is much shorter than for any of these other drugs.

I think that once one of these psychedelic drugs is moved from schedule one to schedule two or schedule three, something like MDMA, either you will see some pharmaceutical interest particularly when you get what's called post-market data in. A drug is moved to prescription status. And then for years afterward, you're able to collect a totally different type of data because you've gone from your clinical trial sample size, which will be a couple hundred people, to five years after it gets the pharmaceutical status you could have had 10 thousand people use the drugs, you could have had 50 thousand.

And so once we know what is most desirable about MDMA in this clinical setting, in this psychiatric setting, and what effects are least desirable, what effects kind of occasionally complicate or sabotage improvement, I suspect that's when you see the pharmaceutical companies saying they would look at that data and say, "Okay. Psychiatrists say that this is the best part of using this drug. This is not a great part. Well, let's make a drug that only has these ideal qualities and none of the bad ones."

Gillespie: Timothy Leary gave out psilocybin in his Good Friday experiments, along with Richard Alpert later, Ram Dass, at Harvard. That was the proximate cause for them getting bounced from Harvard. Leary obviously popularized LSD. He was a big promoter of pot use and stuff. He's kind of the villain, isn't he, in people who do psychedelic research? Talk a little bit about Timothy Leary's kind of ambivalent role or ambiguous role in all of this.

Riggs: He's sort of the guy without whom I'm not sure any of this would be possible, but because of him it hasn't already happened, if that makes sense. If you just look at his credentials, he got his PhD in psychology at UCLA and then he went to Harvard. Had he done everything by the book, had he not fallen in love with LSD, which LSD changed Timothy Leary's life. I mean, it transformed him as a human being and as a thinker. Had it not done all that. Had it remained purely academic for him, I suspect that this research would have never stopped and that maybe some of these drugs would be legal already for medical uses. But at the same time, I don't know if you ever get the national awareness that LSD developed without him.

He's a cautionary tale for contemporary researchers. They recognize that the credentials were necessary, that Leary being at Harvard, for a while, was very helpful, which is why so many of the researchers today, they are at Stanford. They're at UCLA. They're at Imperial College London. They're at Johns Hopkins University. They're at NYU. They're at Brown. I mean, they're just, they're all over the place. Being in those positions of authority and power and respect are really important.

The tricky thing is sort of always maintaining this wall, this firewall between the personal affection that most of these researchers, I won't say all of them because I haven't spoken to all of them, but many of the researchers recognize on a personal level that these drugs are very beneficial for most of the people who use them, even people who use them outside of a psychiatric setting. But in terms of what they say publicly, what they say in their research, they are very consistent and disciplined about saying, "Regardless of what we know anecdotally about these drugs, what we know is wise to recommend is that they only be used under supervision after they've been approved by the FDA." That's because of Leary.

Gillespie: One of the many of the fascinating aspects of your story, you discuss your own use, particularly with ecstasy, I guess. Can you tell us a little bit about that? How does that factor into this broader story of psychedelics kind of on the march for psychological well being and kind of realization of human potential for you?

Riggs: Yeah. It's funny. I kind of waffled a little bit on whether or not to include the personal stuff in my story just because as I was researching this one I was reading Albert Hoffman's memoir, "LSD: My Problem Child." One of the things he talks about this explosion of awareness of LSD in the 1960s and then an increase in recreational use. He blames, I don't know if blame's the right word, but he says that this coincides with a lot of writing about LSD in the popular press. There were a couple of memoirs that came out. Word leaked that Cary Grant, the actor, had used LSD and that it transformed him and made him a better actor.

I felt kind of self conscious about that, as well, because the experiences I've had with psychedelic drugs, namely psilocybin, MDMA, and LSD, but particularly MDMA, have been personally transformative for me. I think most of the people who have known me for many years would say that I'm a different person now than I was four or five years ago. Part of that is because I wasn't leading a particularly sustainable life five or six years ago. But part of it for me was that the transition to a more healthful way of being taking better care of my body, trying to be more diligent about building good habits was kind of aided by the use of psychedelic drugs. Not frequent use, but kind of taking these drugs and then having really intense, in depth, long conversations with intelligent people about how to get better, just how to get better as a person, as a human being, how to be a better neighbor, how to be a better friend. That kind of stuff.

The reason that I was ambivalent to include it in the story is that I only know my own story best, I know it's a good one. And I know lots of people who also have positive stories. But there are people who have bad ones. There are people who have problem use with MDMA. It does have an amphetamine component, which activated dopamine receptors and that makes it a drug that you kind of want to take a lot. So there's addiction issues with MDMA. I've met people who used mushrooms and felt really terrible throughout the entire experience and don't ever want to use them again. LSD is kind of, I mean, that is a real commitment to self exploration. The trip lasts a long time. It distorts your perception of reality in a way that nothing else does.

For me, they've been really important and really amazing and really life-affirming. That's just not true for everyone. I tried to, this is also why I find this whole story interesting is this idea of a lot of these psychedelic researchers, they either had this experience themselves or they know someone who has had this experience. And so, what they want to do is kind of Sherpa these drugs from where they are now to a place where if somebody has a bad reaction on them, they're having it in the presence of a trained clinician who can make sure that they don't hurt themselves. As much as I believe in my body, my choice, and not incarcerating people for what they do to their own bodies, I do see a lot to commend in the movement to make sure that these drugs are used in safe settings.

Gillespie: You're writing at Reason is really a lot about human modification or kind of self-directed evolution almost. How do people, they have an idea of what they want to be like and then they pursue that. Talk a bit about, and you yourself over the past few years, you went on a particularly strict diet and workout regimen, you transformed the way that you look. You had always been what used to be called a husky person, now you're kind of-

Riggs: That's true. Yeah.

Gillespie: Rock hard and all that. What is your interest, and for libertarians in particular, what is the interest in this kind of motivational change of what you look like or what you think like?

Riggs: There are lots of sort of just these moments of awareness that happened as I was nearing the age of 30 in which I was kind of like, "Okay. This is a thing I cannot do forever." One of those was smoking a pack and a half of cigarettes a day. I was like, "I cannot do this forever." My father had a double bypass when he was 52 and had been a lifelong smoker. And so I was just kind of all these things were happening. I was like, "Okay. I can't do this forever." And then the other thing that I realized and that has become a fundamental, philosophical belief for me is that the world has very little interest in how long I live or how well I live.

As someone who believes very much in the phenomenon of spontaneous order and that you don't need a central organizer or planner to make sure that life happens. There's nothing in the theory of spontaneous order that says, "The world will not continuously offer you stuff that will kill you." For me, that has been at various times cigarettes. It's been alcohol. It's been food. It's been inactivity. It's been mindless forms of entertainment. There's no drug I've tried, maybe with the exception of nicotine, that I find as addictive as an Xbox game console.

For me, this was kind of just a realization of things. One, that there was no one in the world who was going to keep me from living a unfortunately short life if I so choose and that some part of me, maybe it's genetic, maybe it's just ingrained through repetition, really preferred a lot of behaviors that were going to shorten my lifespan. I don't know how I feel about living forever or even exceeding what's considered a long, healthy natural life. But I don't like the idea of someone saying, "He died young." And so that was that constellation of sentiments is kind of what led me to change things.

Gillespie: Talk a bit about your kind of career arc because I believe, and if I'm not mistaken, you first came to Reason as an intern. What year would that have been?

Riggs: That was 2008.

Gillespie: Yeah. You were there and then you went on to various other journalism outfits. You worked for Families Against Mandatory Minimums. Give your interest in kind of self ownership in terms of better living through chemistry in many ways and a wakening sense of exercise and diet and things like that, your interests in policy. What's the grand narrative that Mike Riggs is building for himself?

Riggs: That's tricky. I mean, the initial grand narrative. I was an intern at Reason in 2008. I'd been a student journalist in college and turned at a daily newspaper before I left college. But the narrative for a long time was that good art comes from suffering and that the best way to suffer is to kind of self abuse. I was very much a fan of Hunter Thompson and in pretty much any other heavy drinking, big meal eating, writer from the 20th century. I just thought that that was the best way to get stories, was to do crazy stuff, to get ripped or hammered, to always write with a cigarette between my lips. A lot of stuff like that. That was kind of-

Gillespie: This is, if I can say this is William Blake by way of Jim Morrison what the road of excess leads to the palace of wisdom. Something along those lines.

Riggs: Yeah. I mean, basically, I found that way of seeing art and writing and creation very compelling. I struggled for a very long time with the idea of how can you have a happy, healthy, normal life? How can you be someone who gets eight hours of sleep a day, and is a good family man, and doesn't wake up hungover with bloodshot eyes? How can you be all those things and also someone who makes compelling writing? It wasn't so much that I came to believe that this was not true, as it was that I just found it utterly exhausting.

I went from Reason as an intern to the Washington City paper where my personal brand was kind of the insufferable libertine. I also wrote as a libertarian, but it was mostly [illiteracy 00:33:15]. I was mostly like, "Hey, isn't it fun to be reckless all the time?" And then I went to the Daily Caller, which had not yet launched, but I helped Tucker Carlson launch that and kind of developed a reputation while working there. It's very conservative today, but at the time it was so new that I was able to be someone who was also kind of reckless and wild. That was my "personal brand."

I think eventually I just found it exhausting and also it kind of got on my employers nerves after a while. That kind of eventually led to a revisiting and this desire to tell good stories, tell interesting stories, tell true stories, tell hopeful stories, while also leading a life that was not slowly killing me.

Gillespie: You also worked at Families Against Mandatory Minimums, FAMM. How did that play into your interests or your commitments?

Riggs: Yeah. I joined FAMM from the Atlantic. I felt just one step too far removed from what I have basically, the thing I've written about consistently at every journalism job I've ever had is drug policy. I was feeling kind of mildly frustrated. As a young blogger, I was in the habit of saying things like, "Well, if we just did this, we will fix these problems. If we just did this." After a while I kind of wanted to get a little closer and just get a sense of, "Well, what's keeping us from just doing this? What are the obstacles to just doing that?"

So I went to work for Families Against Mandatory Minimums as the director of communications there and got a front row seat to why it is so difficult to change, probably any law, but definitely the laws around drug sentencing for federal drug offenders. That was just an incredible wake up call. I mean, for one thing, this idea that kind of permeates most drug policy writing is we tend to look at somebody who's been incarcerated due to a drug offense and we say, "Hey, they've got kids. Hey, they've never been convicted of a violent crime before. Hey, they're neighbors don't seem to have a problem with them. Why are we putting them in prison for a long time? This doesn't make sense. They're not really bad people that you want to put in prison for a long time."

Working at FAMM, I came to learn pretty deeply and intimately just how little a defendant character or personality or beliefs or circumstances has to do with how long they're sentenced to prison. I mean, which is one of the biggest objections to mandatory minimums is that when you go, one size fits all. When you say, "X quantity of drugs gets you X sentence regardless of whatever mitigating circumstances you may be able to present to the court." That's why one of the reasons why they're so heinous. I mean, you treat the kingpin who's ordered the deaths of dozens of people and the dad who owns a pizza shop and grows a bunch of weed in his backyard to supplement his income, you look at both of them and say, "Your sentence is based on the quantity of drugs you have."

Gillespie: Are you optimistic about drug policy reform in America?

Riggs: Yeah, it's a great question. I mean, at the end of the Obama administration, I would have said yes. I would have said that he did not do enough and that the justice department did not do enough and that I was very frustrated by the opportunities that a seemingly reformed, friendly Congress missed because of partisan bickering. But that I was, for the most part, optimistic that things could only get better. With Attorney General, Jeff Sessions, I don't want to say that all hope is lost, but it is a reminder that whatever policy changes are implemented by way of executive order as opposed to signed, or passed and signed legislation, they are transitory. They don't have to be. Sometimes they aren't. But, for the most part, they're transitory.

I am wondering, I do wonder, what has to change? What has to happen? What does Congress have to look like? Who has to sit in the White House? For those two branches of government to re-visit the cascade of terrible drug laws that they've passed since, well going back to the beginning of the 20th century. But what are the ideal circumstances for that because a republican majority in Congress that seemed to be pro criminal justice reform with a democratic president who was pro criminal justice reform, whatever the allure of some great, bi-partisan bargain is to pundits was not there for them. Now that you have a unified Congress, and a republican President, a republican Congress, whatever allure there is to being able to take full responsibility for implementing some brilliant criminal justice reform. That also doesn't seem to be very compelling.

I do wonder. My optimism is blunted by my curiosity, I guess you could say, about what has to happen for any of this to actually become real.

Gillespie: What is the next story you're working on, Mike?

Riggs: I've got a couple of different ones that I'm thinking about. I will be meeting with my excellent editor, Peter Seederman, to go over them. But I'm looking at a piece about reciprocity, which is the idea that any drug that the European Union approves we should just automatically allow Americans to use as well because it's Europe not Rwanda and so they've got a pretty good drug approval process.

I'm also doing some exploration of the ultimate drug gray market, which is the research chemical market. Most familiar to Americans because of the K2/spice/bath salts epidemic. All of those things were created by academic chemists at universities here in the United States who then published their formulas. And then those things kind of took on a life of their own that became a global phenomenon. That is a piece I'm looking into now is kind of tracing how is that phenomenon born? How does K2 or spice or bath salts, how does that come into existence? Why did it come into existence? And what is the best solution for having people use safer drugs?

Gillespie: I can remember a couple of years ago when K2 or spice was a big thing. There was a great, I forget the newspaper that ran it, but it was a headline that said, "Fake pot as bad as the real thing." It just seemed to kind of sum up a lot of the thinking that goes into the drug war.

Mike Riggs, reporter for Reason. Thank you so much for talking to the Reason podcast. Any last, any message to your fans?

Riggs: Yeah. Be safe.

Gillespie: All right. All right.

Riggs: Be safe. That's always by words of wisdom.

Gillespie: Those are true words of wisdom. Thank you so much, Mike Riggs.

This is the Reason podcast. I am Nick Gillespie for Reason. Thank you so much for listening. Please subscribe to us at iTunes and rate and review us while you're there.

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Countdown To (Legalized) Ecstasy! Rick Doblin, MAPS, & the Psychedelic Renaissance [Podcast] - Reason (blog)

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