Category Archives: Evolution

Webinar Event to Be Held Tomorrow June 29th at 12pm Eastern / 9am Pacific Time

SAN DIEGO, CA, June 28, 2021 (GLOBE NEWSWIRE) -- via NewMediaWire Sigyn Therapeutics, Inc. (OTCMarkets: SIGY), a medical technology company focused on the treatment of sepsis and other life-threatening inflammatory conditions precipitated by Cytokine Storm Syndrome, announced today that its Chairman and CEO, Jim Joyce will participate in a webinar entitled: The Evolution of Blood Purification Technologies to Treat Emerging Pandemic Threats, Including COVID-19. The event will be held tomorrow at 12pm eastern.

Event registration can be accessed through the following link: https://forcewealth.com/portfolio-items/sigyn-06-29/?portfolioCats=28

Prompted by 911 and the October 2001 Anthrax attacks, the industry to support the development of drug and vaccine countermeasures to treat emerging bioterror and pandemic threats was established when President George W. Bush signed Project BioShield into law. Mr. Joyce will review the congressional effort that expanded Project BioShield to be inclusive of blood purification devices and will additionally discuss how COVID-19 has unveiled the ability of blood purification therapies to deliver life-saving mechanisms that are beyond the reach of post-infection drugs. Thus, establishing the potential for an important new industry segment.

Beyond a review of Sigyn Therapy, technologies to be discussed will include the Hemopurifier from Aethlon Medical, the CytoSorb device from CytoSorbents Corporation, Torymyxin from Toray Industries, the Oxiris Filter from Baxter and the Seraph 100 Microbind Affinity Blood Filter from Exthera Medical.

Note: In addition to co-founding Sigyn Therapeutics, Mr. Joyce was the founder of Aethlon Medical and oversaw the development of the Aethlon Hemopurifier.

About Sigyn Therapeutics

Sigyn Therapeutics is focused on significant unmet need in global health; the treatment of life-threatening inflammatory conditions that are precipitated by Cytokine Storm Syndrome. The annual market opportunity exceeds $20 billion.

Sigyn Therapy is a multifunctional blood purification technology designed to mitigate the Cytokine Storm that underlies Sepsis (the #1 cause of in-hospital deaths) and other high-mortality inflammatory disorders commonly induced by bacterial and viral pathogens. To overcome the limitations of previous therapies, Sigyn Therapy addresses the source of inflammation (viral pathogens, bacterial toxins) in concert with the broad-spectrum depletion of inflammatory cytokines from the bloodstream. Additionally, the device establishes a therapeutic strategy to target CytoVesicles that transport inflammatory cargos throughout the circulatory system.

Sigyn Therapy incorporates a formulation of adsorbent components that optimize the broad-spectrum elimination of therapeutic targets from the bloodstream without the risk of direct blood-cell interactions. To support widespread implementation, Sigyn Therapy is a single-use disposable device designed for use on the established infrastructure of hemodialysis and continuous renal replacement therapy (CRRT) machines already located in hospitals and clinics worldwide. The Company is also conducting studies to evaluate the potential use of Sigyn Therapy to treat acute forms of liver failure, including hepatic encephalopathy.

To learn more, visit http://www.SigynTherapeutics.com

Cautionary Note Regarding Forward-Looking Statements

This press release contains forward-looking statements of Sigyn Therapeutics, Inc. (Sigyn) that involve substantial risks and uncertainties. All statements contained in this press release are forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. The words could, will, plan, intend, anticipate, approximate, expect, potential, or the negative of these terms or other similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. These forward-looking statements include, among others, statements about Sigyns future financial performance, the impact of management changes, any proposed organizational restructuring, results of operations, capital resources to fund operations; statements about Sigyns expectations regarding the capitalization, resources and ownership structure of the combined company; statements about the potential benefits of the transaction; the expected completion and timing of the transaction and other information relating to the transaction; and any other statements other than statements of historical fact. Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements that Sigyn makes due to a number of important factors, including (i) the risk that the transaction may not be completed in a timely manner or at all, which may adversely affect Sigyns business and the price of the common stock of Sigyn, (ii) the failure to satisfy of the conditions to the consummation of the transaction, (iii) the occurrence of any event, change or other circumstance that could give rise to the termination of the merger agreement, (iv) risks related to the ability to realize the anticipated benefits of the transaction, including the risk that the businesses will not be integrated successfully, (v) the effect of the announcement or pendency of the transaction on Sigyns business relationships, operating results and business generally, (vi) risks that the proposed transaction disrupts current plans and operations, (vii) risks related to the combined entitys ability to up-list to a national securities exchange, (viii) risks related to the combined entitys access to existing capital and fundraising prospects to fund its ongoing operations, (ix) risks related to diverting managements attention from Sigyns ongoing business operations, (x) other business effects, including the effects of industry, market, economic, political or regulatory conditions, future exchange and interest rates, and changes in tax and other laws, regulations, rates and policies, and (xi) risks related to an inability to manufacture Sigyn Therapy, risks related to the clinical advancement of Sigyn Therapy with regulatory agencies, and no assurance that Sigyn Therapy will be proven to be a safe and efficacious treatment for any condition. The forward-looking statements in this press release represent Sigyns views as of the date of this press release. Sigyn anticipates that subsequent events and developments may cause its views to change. However, while it may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. You should, therefore, not rely on these forward-looking statements as representing Sigyns views as of any date subsequent to the date of this press release.

Media Contacts:Russo Partners, LLCDavid Schull(212) 845-4271David.Schull@russopartnersllc.com

Nic Johnson(212) 845-4242Nic.Johnson@russopartnersllc.com

Corporate Contact:Jim JoyceChairman, CEO(619) 368-2000jj@sigyntherapeutics.com

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The Evolution of Blood Purification Technologies to Treat Emerging Pandemic Threats, Including COVID-19 - GlobeNewswire

THE WOODLANDS, TX -- Many of us reflected during the pandemic about how we spent our time at work. Are we spending 50 plus hours each week or much of our time at a job that does not bring joy to our livelihood? The pandemic has reshaped out thoughts on taking a risk and leaving a job that doesnt make us happy. More than 40% of people have left their jobs in 2021 already.

Thoughts of trying out a new career, working in an industry that excites us every day or strategizing on starting our own business presents possibilities. Many businesses are shifting to a varied work schedule with part of the time working remotely or possibly all office work is done remotely as they downsize expenditures for office space and embrace virtual working. An alternative professional work environment is here to stay.

Office Evolution of The Woodlands (OE) is celebrating a two-year anniversary this month. The pandemic has increased the amount of business minded people looking to change up the way they live, and reducing the commute is one way to do that. Office Evolution is located close to the Woodforest community, Stillwater, Del Webb, and Lake Windcrest, the location is ideal for a convenient office space located at 525 Woodland Square Blvd off FM 1488 in the Marcel Town Center.

With over 400 parking spaces and 6 restaurants, tenants leasing office space are never inconvenienced looking for space in a garage or leaving for lunch. As the market changes and more individuals are considering a fresh start with self-employment, many small business startups are creating the foundation for their new venture by bundling services with a professional plan to include the mailbox business address, the phone messaging services by a live person, meeting room discounts, and shared workspaces.

Currently at a 70% capacity and growing the workplace suites offer viable solutions logistically and financially. Phil Anderson and his franchise partner Roger Tietze, encourage the community to explore their office space and see for themselves the convenience of an easy drive, easy parking, and accessibility for lunch or dinner meetings. Its okay to be here all day, its okay to bring in your own food, or do pick up at 6 restaurants here in the center. Office Evolution has their own mini kitchen with free Wi-Fi internet, coffee, tea, and water.

Clients enjoy the family, comfortable attitude when they walk in our door said Phil Anderson, franchise partner at Office Evolution. We call it Ohana. OHANA is Hawaiian for big family. We are dedicated to making your dreams come true. We are a business- but we are a 'family' business since we are a network of local owner operated locations 70+ locations nationwide.

If your business hosts events or sees clients in an office, the workspace offered at Office Evolution is ideal. The offices are designed in contemporary bright colors with windows that allow for natural lighting. The training/conference room is a beautiful contemporary space with 105 -inch white board and 75- inch Smart TV. Guests are always welcomed by a friendly receptionist at the front desk as they enter. Face to face interactions build relationships and a key element to business success. If you are having Virtual Conference calls, job interviews or inviting other professional partners to your office it is a great impression to be met at the desk by a receptionist.

Each office space has their own key to their locked furnished office, phone number, personalized voicemail, live phone answering service, private mailbox with physical address, secure Wi-Fi internet service, meeting rooms, and a shared lounge area with a community kitchen. Members can access their workspace 24/7 at the home location or any of the 70 Office Evolution locations nationwide. Postal services, a business address, phone services and printing options are available upon request.

Watermere at Woodlands Lakes, a retirement community is nestled to the back of the Marcel Shopping Center. If your business is targeted to adults over 55 you have both Watermere and Del Webb steps away from Office Evolution.

Jo Smith of MHW Real Estate was looking for a meeting room to conduct a half day conference and left a Google Review on June 22, Tina answered my call and quickly answered all my questions with assurance that she could provide the perfect room with a window view. She made the booking process easy with no advance deposit needed with up to 48 hours to cancel if necessary. The great customer service and amenities offered gave me confidence that our team with have a productive and fun meeting!.

Another Google Reviewer posted this comment: It's the little things that make OE an excellent place to do my business. The desk and table heights are perfect. The chairs are comfortable and supportive. The facility is always clean. The lighting is bright, but not glaring, and the colors are inviting. My clients LOVE the comfort and professionalism here. The feeling of family is strong at OE. The owners and operators are always so helpful and encouraging; it actually feels as if they are business coaches, and I have never felt like just a 'customer' to them. They want my business to succeed as much as I do. And I get the same treatment, whether utilizing the most basic package, or the upgraded plan. Can't wait to have a full-time office here in the future.

'If you don't need a lot of services, talk to the OE staff about your individual needs including postal services, a business address, phone services, and printing options, said Phil Anderson. We can accommodate your professional needs on an individual basis.

For their 2-year Anniversary Office Evolution is offering the podcast studio for $25/hour with a 2-hour limit. Book it by emailing woodlands.tx@officeevolution.com or calling Tina Asma at (936) 270-1150.

Gain the edge on your competition with new opportunities by updating your technology presence with a podcast. A special introductory offer provides new office members with a two-hour/month allowance to use the podcast studio with all the equipment you need. Through a partnership in the community your podcast will have a landing page to direct listeners, too.

Take the risk and step into your new workspace-Office Evolution, The Woodlands.

For more information about Office Evolution-The Woodlands visit http://www.officeevolution.com/locations/woodlands or call 936-270-1150. Follow them on Facebook, http://www.facebook.com/Office-Evolution-Woodlands

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Office Evolution Celebrating 2 year Anniversary with Office Solutions - Woodlands Online

Mitsubishis president and CEO, Takao Kato, has revealed when the brand could start offering the cars that fans are waiting for, Evolution XI included, with its returning Ralliart sub-brand to lead the way.

According to Japanese publication Response, Mitsubishi shareholders had asked for the Evolution series to be revived, although Mr Kato told them at their annual general meeting on June 23 that firm plans for an 11th instalment remain off the table for now.

Electrification costs a lot of development costs, and the company is still not strong enough. We had a big deficit in the previous fiscal year, so we first revived the company and then put out the cars that fans are waiting for, he said via translator.

Needless to say, Mitsubishi is obviously prioritising its financial health, with its ongoing electric vehicle (EV) transition key to its long-term future. That said, once the ball is well and truly rolling there, the door is still open for the eagerly anticipated Evo XI.

In the meantime, the brand committed to the Ralliart sub-brands return in May, with Mr Kato having now confirmed we plan to expand it to a wide range of models as genuine accessories first. As reported, the Triton ute is set to be the first to receive the treatment.

And if the Evolution series is revived down the line, its increasingly unlikely to be based on the Lancer small car, as per the previous 10 instalments, although there are conflicting reports as to what form it would take.

Autocar claimed in June 2019 that Evo XI would share its CMF-C/D platform with the next-generation Megane RS hot hatch, which still makes a lot of sense given Mitsubishi and Renault make up two-thirds of the Renault-Nissan-Mitsubishi Alliance.

The UK publication also said the Evo XI was due around 2022 and would be motivated by a 2.0-litre turbo-petrol four-cylinder engine with about 255kW of power and 450Nm of torque, and a 48V mild-hybrid system. Again, all of that sounded plausible.

That said, Mitsubishi heavily hinted at a very different direction for the high-performance Evolution series when it revealed the e-Evolution concept, an all-electric SUV, at the Tokyo motor show in October 2017.

Fast forward to January this year,Response reported the production version of the e-Evolution concept would be revealed later in 2021, but with two electric motors instead of three.

It goes without saying that this potential new model is likely to be mechanically related to the zero-emissions Nissan Ariya mid-size crossover, which is available with a 290kW/600Nm powertrain that wouldnt be out of place in the Evolution series.

Adding fuel to this fire is Mr Kato, who also said: We would like to create a car that allows customers to experience the electrification technology, SUV technology with high off-road driving performance, and the comfort performance in a functional and enjoyable space.

Its easy to put two and two together there, but time will tell if this model will be part of the Evolution series. Either way, fans will have to wait that little longer to find out what does or doesnt happen.

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Will Mitsubishi's Ralliart return lead to Evolution XI? Brand boss reveals when the iconic performance model could make its comeback - CarsGuide

The Jurassic World Evolution 2 team recently discussed the four key areas that the sequel will focus on: an authentic narrative, deeper management, enhanced creativity, and realistic dinosaurs. Game director Rich Newbold said that everything in the game should be working towards at least one of those key ideas. With an authentic narrative, the teams wants to push the narrative aspects of the sequel, with a story set after Fallen Kingdom. It's the idea of enhanced creativity that's most interesting, however one of the drawbacks of Jurassic World Evolution was its limitations with customisation and terrain tools, but Newbold says they're adding extra tools and opportunities for you to really customise... and build those parks of your dreams."

Another issue with the first game was the limits of its management mechanics, but Newbold says they're aiming for deeper management with the sequel. We wanted to add a lot more levers, a lot more things that the player is doing whilst theyre managing their parks, when it comes to the guests, the dinosaurs building that park and managing that park and dealing with the moment-to-moment aspects of running a dinosaur theme park." By the time you got to grips with the first game you'd often have quite a bit of downtime while new dinosaurs were being created, research was being completed, excavation teams were off fossil-hunting, or new buildings were being constructed. From the sound of things, the sequel will bring us more to do, and hopefully cut out some of that downtime. Frontier recently detailed a few of the new features coming with the sequel, such as a territory system and wild dinosaurs, tying into the game's fourth pillar: realistic dinosaurs. Newbold adds that the game features over 75 different prehistoric species," and that this realism will be achieved with "a lot more depth in their behaviours, in the way they move around your landscapes and environments, how they interact with each other." We had a glimpse of dino behaviour in two new Species Field Guide videos, where we also saw another of Jurassic World Evolution 2's new features, as two Amargasauruses were released at the same time.

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Jurassic World Evolution 2 will focus on "enhanced creativity, deeper management" and more - TrueAchievements

Anne Hathaway, in hot pink cargo trousers and a knitted cardigan, attends the Fox Teen press junket at Planet Hollywood in Los Angeles, California, on July 23, 1999. Globe Photos

Anne Hathaway, in a strapless LBD, attends the 'Nicholas Nickleby' premiere at Warner Village Cinema on June 22, 2003 in London, England. Getty Images

Anne Hathaway, in Christian Lacroix, arrives at the 59th annual Tony Awards at Radio City Music Hall on June 5, 2005 in New York, US. EPA

Anne Hathaway, in a lace-trimmed strapless dress, attends a photo call for 'Brokeback Mountain' at the 62nd Venice Film Festival on September 2, 2005 in Venice, Italy. Getty Images

Anne Hathaway, in an asymmetric tiered dress, attends the premiere for 'Brokeback Mountain' at the 62nd Venice Film Festival on September 2, 2005 in Venice, Italy. Getty Images

Anne Hathaway, in a teal mini dress, attends a party for 'The Devil Wears Prada' at Casino di Venezia on September 6, 2006 in Venice, Italy. Getty Images

Anne Hathaway, in a polka-dot dress, attends a photo call for 'The Devil Wears Prada' during the 63rd Venice Film Festival on September 7, 2006 in Venice, Italy. Getty Images

Anne Hathaway, in Alberta Ferretti, attends the premiere of 'The Devil Wears Prada' at the 63rd Venice Film Festival on September 7, 2006 in Venice, Italy. Getty Images

Meryl Streep and Anne Hathaway, in a gold-trimmed LBD, attend 'The Devil Wears Prada' premiere at the 32nd Deauville Festival on September 9, 2006 in Deauville, France. Getty Images

Anne Hathaway, in Valentino, arrives at the Valentino in Rome: 45 Years of Style gala dinner at the Imperial Forum on July 6, 2007 in Rome, Italy. Getty Images

Anne Hathaway, in Marchesa, arrives for the 80th annual Academy Awards at the Kodak Theatre in Hollywood, California, on February 24, 2008. EPA

Anne Hathaway, in a red dress with voluminous sleeves, attends the premiere of 'Get Smart' at Movie World on June 22, 2008 in the Gold Coast, Australia. Getty Images

Anne Hathaway, in Valentino, attends the 'Get Smart' premiere at Warner Moderno Cinema on July 7, 2008 in Rome, Italy. Getty Images

Anne Hathaway, in Lela Rose, attends a 'Rachel Getting Married' photo call at the 65th Venice Film Festival on September 3, 2008 in Venice, Italy. Getty Images

Anne Hathaway, in Versace, attends the premiere of 'Rachel Getting Married' at the 65th Venice Film Festival on September 3, 2008 in Venice, Italy. Getty Images

Anne Hathaway, in Armani, arrives for the 66th annual Golden Globes at the Beverly Hilton Hotel in Beverly Hills, California, on January 11, 2009. EPA

Anne Hathaway, in Gianfranco Ferre, attends a photo call for 'Bride Wars' at Hotel George V on January 19, 2009 in Paris. Getty Images

Anne Hathaway, in Armani, arrives at the 81st Academy Awards at the Kodak Theatre in Hollywood, California, on February 22, 2009. EPA

Anne Hathaway, in Armani, attends the Giorgio Armani show during Paris Fashion Week on January 25, 2010 in Paris, France. Getty Images

Anne Hathaway, in Marchesa, arrives at the premiere of 'Valentine's Day' in Los Angeles, California, on February 8, 2010. EPA

Anne Hathaway, in Vivienne Westwood, arrives for the 'Alice in Wonderland' after party at The Sanderson Hotel on February 25, 2010 in London, England. Getty Images

Anne Hathaway, in Valentino, arrives at the Met Gala at the Metropolitan Museum of Art in New York, US, on May 3, 2010. EPA

Anne Hathaway, in Oscar de la Renta, and Jake Gyllenhaal attend the premiere of 'Love and Other Drugs' at Event Cinemas George Street on December 6, 2010 in Sydney, Australia. Getty Images

Anne Hathaway, in Giorgio Armani, arrives for the 68th Golden Globe Awards at the Beverly Hilton Hotel in Los Angeles, California, on January 16, 2011. EPA

Anne Hathaway, in Valentino, arrives for the 83rd annual Academy Awards at the Kodak Theatre in Hollywood, California, on February 27, 2011. EPA

Anne Hathaway, in Gucci, arrives for the premiere of 'Rio' at Grauman's Mann Chinese Theatre in Hollywood, California, on April 10, 2011. EAPA

Anne Hathaway, in Valentino, attends the White Fairy Tale Love Ball at Chateau de Wideville on July 6, 2011 in Crespieres, France. Getty Images

Anne Hathaway, in Alexander McQueen, attends the premiere of 'One Day' at The Vue Westfield on August 23, 2011 in London, England. Getty Images

Anne Hathaway, in Giambattista Valli, arrives at the Kennedy Centre Honours at the US Department of State in Washington, DC, on December 3, 2011. EPA

Anne Hathaway, in Gucci, attends the premiere of 'The Dark Knight Rises' at Odeon Leicester Square on July 18, 2012 in London, England. Getty Images

Anne Hathaway, in Givenchy, attends the 'Les Miserables' premiere at the Odeon Leicester Square on December 5, 2012 in London, England. Getty Images

Anne Hathaway, in Chanel, arrives for the 70th annual Golden Globe Awards at the Beverly Hilton Hotel in Los Angeles, California, on January 13, 2013. EPA

Anne Hathaway, in Giambattista Valli, arrives for the 19th annual Screen Actors Guild Awards at the Shrine Auditorium in Los Angeles, California, on January 27, 2013. EPA

Anne Hathaway, in Prada, attends the 'Les Miserables' premiere at Cinema Gaumont Marignan on February 6, 2013 in Paris, France. Getty Images

Anne Hathaway, in Chanel, attends the 'Les Miserables' photo call during the 63rd Berlinale International Film Festival at Grand Hyatt Hotel on February 9, 2013 in Berlin, Germany. Getty Images

Anne Hathaway, in Burberry, attends the Baftas at The Royal Opera House on February 10, 2013 in London, England. Getty Images

Anne Hathaway, in Prada, attends the 85th Academy Awards at the Dolby Theatre in Hollywood, California, on February 24, 2013. EPA

Anne Hathaway, in Valentino, and Valentino attend the Met Gala at the Metropolitan Museum of Art in New York, US, on May 6, 2013. EPA

Anne Hathaway, in Gucci, arrives for the 86th annual Academy Awards at the Dolby Theatre in Hollywood, California, on March 2, 2014. EPA

Anne Hathaway, in Calvin Klein, arrives for the Met Gala at the New York Metropolitan Museum of Art in New York, US, on May 5, 2014. EPA

Anne Hathaway, in Richard Nicoll, arrives for the premiere of 'Interstellar' at the TCL Chinese Theatre in Los Angeles, California, on October 26, 2014. EPA

Anne Hathaway, in Wes Gordon, attends the premiere of 'Interstellar' at Odeon Leicester Square on October 29, 2014 in London, England. Getty Images

Anne Hathaway, in Chanel, attends the 'Interstellar' premiere at UME Cinema on November 10, 2014 in Shanghai, China. Getty Images

Anne Hathaway, in Ralph Lauren, attends the Met Gala at the New York Metropolitan Museum of Art in New York, US, on May 4, 2015. EPA

Anne Hathaway, in Jonathan Simkhai, attends the premiere of 'The Intern' at Vue West End on September 27, 2015 in London, England. Getty Images

Anne Hathaway, in Naeem Khan, attends the Vanity Fair After Party following the 88th annual Academy Awards in Hollywood, California, on February 28, 2016. EPA

Anne Hathaway, in Christopher Kane, attends the premiere of 'Alice Through the Looking Glass' at the El Capitan Theatre in Hollywood, California, on May 23, 2016. EPA

Anne Hathaway, in Valentino, attends the Met Gala at the Metropolitan Museum of Art in New York, US, on May 7, 2018. EPA

Anne Hathaway, in Jean Paul Gaultier, arrives for the premiere of 'Ocean's 8' at Alice Tully Hall in New York, US, on June 5, 2018. EPA

Anne Hathaway, in Givenchy, attends the Givenchy show as part of Paris Fashion Week on September 30, 2018 in Paris, France. Getty Images

Anne Hathaway, in Valentino, arrives for the 22nd annual Hollywood Film Awards at the Beverly Hilton Hotel in Beverly Hills, California, on November 4, 2018. EPA

Anne Hathaway, in Elie Saab, arrives for the 76th annual Golden Globe Awards at the Beverly Hilton Hotel in Beverly Hills, California, on January 6, 2019. EPA

Anne Hathaway, in Valentino, receives a star on the Hollywood Walk of Fame in Hollywood, California, on May 9, 2019. EPA

Anne Hathaway, in Versace, attends the 25th annual Critics Choice Awards in Santa Monica, California, on January 12, 2020. EPA

Anne Hathaway, in Michael Kors, arrives for the premiere of 'The Last Thing He Wanted' at the Sundance Film Festival in Park City, Utah, on January 27, 2020. EPA

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Anne Hathaway's style evolution in 55 photos: from 'The Princess Diaries' to red carpet queen - The National

A new study published in Nature Communications finds that piles of sand grains, even when undisturbed, are in constant motion. Using highly-sensitive optical interference data, researchers from the University of Pennsylvania and Vanderbilt University present results that challenge existing theories in both geology and physics about how soils and other types of disordered materials behave.

Most people only become aware of soil movement on hillsides when soil suddenly loses its rigidity, a phenomenon known as yield. Say that you have soil on a hillside. Then, if theres an earthquake or it rains, this material thats apparently solid becomes a liquid, says principal investigator Douglas Jerolmack of Penn. The prevailing framework treats this failure as if its a crack breaking. The reason thats problematic is because youre modeling the material by a solid mechanical criterion, but youre modeling it at the point at which it becomes a liquid, so theres an inherent contradiction.

Such a model implies that, below yield the soil is a solid and therefore should not flow, but soil slowly and persistently flows below its yield point in a process known as creep. The prevailing geological explanation for soil creep is that it is caused by physical or biological disturbances, such as freeze-thaw cycles, fallen trees, or burrowing animals, that act to move soil.

In this study, lead author and Penn Ph.D. candidate Nakul S. Deshpande was interested in observing individual sand particles at rest which, based on existing theories, should be entirely immobile. Researchers have built models by presuming certain behaviors of the soil grains in creep, but no one had actually just directly observed what the grains do, says Deshpande.

To do this, Deshpande set up a series of seemingly simple experiments, creating sand piles in small plexiglass boxes on top of a vibration isolation worktable. He then used a laser light scattering technique called diffusing-wave spectroscopy, which is sensitive to very small grain movements. The experiments are technically challenging, Deshpande says about this work. Pushing the technique to this resolution is not yet common in physics, and the approach doesnt have a precedent in geosciences or geomorphology.

Deshpande and Jerolmack also worked with long-time collaborator Paulo Arratia, who runs the Penn Complex Fluids Lab, to connect their data with frameworks from physics, materials science, and engineering to find analogous systems and theories that could help explain their results. Vanderbilts David Furbish, who uses statistical physics to study how particle motions influence large-scale landscape changes, provided explanation for why previous models were physically inadequate and inconsistent with what the researchers had found.

The first experiments were seemingly easy: Pour a pile of sand into the box, let it sit, and watch with the laser. But the researchers discovered that, while intuition and prevailing theories say that the undisturbed piles of sand should be static, sand grain piles are in fact a mass of constant movement and behave like glass.

In every way that we can measure the sand, it is relaxing like a cooling glass, says Deshpande. If you were to take a bottle and melt it, then freeze it again, that behavior of those molecules in that cooling glass are, in every way that were capable of measuring, just like the sand.

In physics, glass and soil particles are classic examples of a disordered system, one whose constituent particles are arranged randomly instead of in crystalline, well-defined structures. While disordered materials, a major focus area of Penns Materials Research Science & Engineering Center, share some common behaviors in terms of how they deform when stressed, there is an important difference between glass and a pile of sand. The molecules that make up glass are always moving randomly at a rate that depends on temperature, but sand grains are too large to do that. Because of that, physicists expect that a pile of sand would be jammed and unmoving, but these latest findings present a new way of thinking about soil for researchers in both physics and geology.

Another surprising result was that the rate of creeping soil could be controlled based on the types of disturbances used. While the undisturbed sandpile continued to creep for as long as the researchers observed, the rate of particle motion slowed through time in a process called aging. When sand particles were heated, this aging was reversed such that creep rates increased back to their initial value. Tapping the pile, in contrast, accelerated aging.

We tend to think of things that drive soil toward yield, like shaking from an earthquake that triggers a landslide, but other disturbances in nature potentially drive soil further away from yield, or make it harder for a landslide to happen, says Jerolmack. Nakuls ability to tune it further or closer to yield was like a bomb that went off for us, and this is an all-new area.

In the near term, the researchers are working on follow-up experiments to recreate the impacts of localized disturbances using magnetic probes to understand how disturbances could lead a system further away from or closer to yield. They are also looking at data from field observations, from natural soil creep to catastrophic landslide events, to see if they can connect their lab experiments to what observers see in the field, potentially enabling new ways to detect catastrophic landscape failures before they happen.

The researchers hope that their work can be a starting point for refining existing theories that rely on a paradigm that, like a hillside whose soil particles have shifted over time, no longer holds weight. When you observe something really counterintuitive and new, its going to now take a long time before that turns into a model to use, says Jerolmack. I hope on the geoscience side that people with sophisticated tools and techniques and experience will pick up where weve ended and say, I have a new idea for seeking this signature in the field that you wouldnt have thought ofthat natural handoff of scales and abilities and interests.

Paulo Arratia is a professor in the departments of Mechanical Engineering and Applied Mechanics and Chemical and Biomolecular Engineering in the School of Engineering and Applied Science at the University of Pennsylvania.

Nakul S. Deshpande is a Ph.D. candidate in the Department of Earth & Environmental Science in Penns School of Arts & Sciences.

Douglas Jerolmack is a professor in the Department of Earth & Environmental Science in Penns School of Arts & Sciences and holds a secondary appointment in the departments of Mechanical Engineering and Applied Mechanics in the School of Engineering and Applied Science.

This research was supported by Army Research Office Grant W911NF-20-1-0113 and National Science Foundation Materials Research Science and Engineering Center Grant DMR-1720530.

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Shifting sands, creeping soils, and a new understanding of landscape evolution | Penn Today - Penn Today

From dark bangs to platinum blonde waves, theres no denying that Khlo Kardashian has had quite the beauty evolution since stepping into the spotlight.

Rewind to 2007, when Keeping Up With the Kardashians premiered, and the 37-year-old reality star was hitting red carpets with jet black hair and heavy smoky eyes.

Fast forward to today, and the Good American founder has had quite the transformation. Shes gone through an amazing fitness journey, switched up her hair color more times then we can count, had a nose job and mastered her contouring technique.

If you ask Us, Kardashian looked fabulous at every stage of the game. But, shes certainly had to face her fair share of critics when it comes to her appearance and it hasnt always been the easiest to deal with.

During part two of the Keeping Up With the Kardashians reunion, the reality star admitted to Andy Cohen that speculation around her plastic surgery has gotten under her skin through the years.

Everyone says, Oh my gosh, shes had her third face transplant. But Ive had one nose job Dr. Raj Kinodia and everyone gets so upset, like, Why dont I talk about it, she said during the special. No ones ever asked me. Youre the first person in an interview thats ever asked me about my nose. Ive done, sure, injections not really Botox.

While the businesswoman admitted to the above, internet trolls always have something to say about Kardashians appearance, claiming that she looks different, had her eyes pulled back or that her forehead looks bigger in recent years.

Earlier this month, one critic even said that she looked like an alien in a commercial for Nurtect. Kardashian responded: Sorry you feel that way. You have every right to block/mute me. I am trying to help many out there who suffer in silence I dont think you should refer to yourself as a feminist if you are attacking a woman unprovoked.

Haters aside, the Revenge Body host always knows how to bring it when it comes to glam. She frequently works with hair colorist Tracey Cunningham and hair stylist Andrew Fitzsimons.

She switches up her style fairly frequently, going from tight braids to big bouncy waves. Her hair color chances on the regular as well, but blonde will always be her personal favorite.

My heart is with blonde. But sometimes a girl just needs to change. Ill always go back to blonde I Just think I need a little something different right now, she wrote via Twitter in 2020, after dyeing her hair brunette.

As for makeup? KoKo frequently works with makeup artist Ash K. Holm. The duo has created looks ranging from soft neutrals and coppers to summery peaches. But, without fail, Kardashian is always rocking a set of falsies and a lined lip.

So, in honor of her 37th birthday, keep scrolling to take a look back at Khlos beauty transformation, from the KUWTK premiere to present day.

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See Khloe Kardashians Beauty Evolution Since the Start of KUWTK - Us Weekly

[WARNING: The following contains MAJOR spoilers for Bosch Season 7.]

Titus Wellivers Harry Bosch witnessed two of the most important people in the homicide detectives life reach a crossroads. A daughter in Maddie and a long-time partner in Jerry Edgar.

TV Insider chatted with stars Madison Lintz and Jamie Hector respectively to talk about their Bosch journey during the Amazon series seventh and final season.

Maddie was inadvertently put into the crossfire of a hitman during a case investigation. One that left her mentor Honey Chandler [Mimi Rogers] shot and fighting for her life in the hospital. Ultimately, a shootout in the parking lot of a courthouse followed. The experience further motivated Maddie to follow her dad into law enforcement.

It was a shock to me, Lintz said, upon reading the script. I just thought she was just going to be a prosecutor. That was fine with me. I thought it was incredible and loves Honey Chandler. That would have been a really great path for her. Deep down, I always hoped she would become a cop. On my Pinterest board for Maddie Bosch, I feel like I manifested it a little bit. Just kidding. It was the incredible writers and producers who decided that. It felt like a surreal moment filming the scene.

The actress believes Maddie also came to the realization that things happen to the people in her life that were out of her control. Becoming a cop is a way to bring change.

Being a prosecutor is not enough. I have to get closer, Lintz added. In a way, that is very valiant and a testament to who her father is and who she is. They are protectors who do the right thing. In other ways, it is how she has dealt with her own grief.

Prime Video

One of the most emotional scenes comes when Madie opens up to her boyfriend Antonio (Jonny Rios). She breaks down about missing her late mother Eleanor (Sarah Clarke), a former FBI agent who was murdered years prior.

I think what happened to Honey opened up a lot of that, Lintz said. Her mom died when she was 16 or 17. That is hard and dealt with the best she could. Now that she is an adult, it spurred out an opening of grief, which was necessary for her to deal with it in an adult way.

Maddie is making moves, literally, leaving dads house to share a place with her boyfriend. She meets Harry at Musso and Frank to tell him the news of her career aspirations.

What I dont think Maddie realizes is she is becoming more of her own person, Lintz said. She is becoming her fathers daughter, but becoming her own person is making these decisions without telling anybody. That shocks Harry a little bit, which is funny to watch. Its part of growing up. I think she wanted him to be excited but understood how the news coil is jarring.

Amazon Prime

Lintz was delighted to find out Maddies story is just beginning with the not-yet-titled Bosch spinoff on the horizon. She is grateful to spend the summer months working on the project, as well as further digging into the role.

One of the things I love about Maddie is she has grown up in that world. She knows the darkness. She has seen what happens to people in law enforcement, yet chooses to go into it anyway. Ive been working with (real detectives) Mitzi [Roberts] and Tim [Marcia] the last couple of months. They are on set.

Ive gained so much from them and they are so much about what they do. Being able to experience and learn and sink your teeth in a different profession for the sake of your own profession is the craziest thing ever. Ive been watching bodycam footage on YouTube. I watched End of Watch with Jake Gyllenhaal because a few producers told me that was a good one to watch. It has been an incredible experience. I find it so fascinating all the facets of the job. I just want to portray it as real as possible. That is my main angle for all of this. I want to do it justice.

Jerry is still deeply affected by his decision to fire on and kill Haitian drug kingpin Jacques Avril (Treva Etienne). Did he let revenge get the better of his judgment? A question that leads to the normally straight-laced J. Edgar to unravel, looking to the comfort of strippers and nicotine to ease the pain. Its impacting not only his personal life but compromising cases as well.

Sometimes its not what you affect. Its what affects you, Hector said. Him grappling, having to take a life. Even though that person was on the other side of the law, its showing up at his doorstep. Its affecting him emotionally, physically, mentally. He always has his suit tailored and ready to go.

There are people who experience what he goes through in their lives. There is still hope for him and there is still another day. Hopefully, it can show other people that its very possible to get beyond your hurt with time and support and seeing the world a little differently.

Prime Video

Jerry lets his emotions get the better of him during questioning, which puts Maddie in danger. He ends up being the saving grace at the courthouse, helping stop the hitman and providing some kind of redemption. It was also a wake-up call Harry wanted him to have long before the incident. Though for Hector, Jerry remains a work in progress.

He doesnt want the responsibility of having lost another life based on the choices and decisions that he made. And not just another life, but someone who is like another daughter, Maddie, he said. For him to be the one who almost causes her death because he couldnt keep his mouth shut. The fact Harry and everyone almost lost their lives in an ambush, which would have been because of him. He knew what he needed to do. This all also pulls him out of that dark abyss. Knowing if he stayed in that place things will only get worse if he keeps making these foolish moves.

With Jerry reassigned to RHD (Robbery-Homicide Division) and Harry going private, the series finale marks the end of an era for this partnership. Hectors focus is now on his next project We Own This City where hell play Sean M. Suiter, Baltimore, well, a homicide detective. In Hectors eyes, the job is similar but the role is someone new.

Amazon Prime

Youre dealing with different people. It focuses on the rise and fall of the Baltimore Police Departments Gun Trace Task Force. They are both detectives but its really about the human behind the profession. Its about the ups and downs, the ins and outs. Its not just about solving a crime, but how he solves the crime. How he thinks and sees the world and impulses. My approach to this new character is to understand who he was and not judge him, but express him as best I can.

The project will see him reunited withThe Wire EP David Simon and producer George Pelecanos. Hector enjoyed the wink to the show when Jerry revealed to be a fan.

I called my family and said, Listen to this line. It really brings it back, he said. Shout out to Eric Overmyer and Michael Connelly for having that into the script, our showrunner, and executive producer. Eric also worked on The Wire as well and we knew each other, so to bring that into it here in the last season of the season, I loved it.

Thanks to the IMDB TV spinoff, this isnt the end of Boschs story. And Hector isnt entirely sure its the end of Jerrys either.

Im looking forward to that call one day because come on, its Bosch, Hector said. It would be fun to play in that sandbox again.

Bosch, Seasons 1-7, Streaming Now, Amazon Prime Video

Read the rest here:

Bosch: The Evolution of Jerry Edgar and Maddie Over 7 Seasons - TV Insider

As a designer, Matthew Williams switches between two different thinking caps. Being at the helm of two very different brands Givenchy, a house steeped in history, and his own street-infused venture, 1017 Alyx 9SM means his design style is inherently versatile.

1017 Alyx 9SM spring/summer 2022.

Each season, Williams caters to the distinct character of both brands. For his Alyx spring/summer 2022 presentation, he harked back to influences he has experimented with in the past. The results were unveiled in a film directed by Jordan Hemingway, set against the backdrop of the mystical volcanic Aeolian island of Stromboli.

Models traversed the dramatic landscape wearing slinky maxi and mini dresses, unzipped oversized hoodies and Alyxs trademark metallic hardware. Hand-embroidered glass bead dresses, tops and skirts were dressed down in classic Williams fashion, with chunky, clog-like flats and angular sunglasses.

To mark the release of his spring/summer 2022 collection, British Vogue caught up with Williams to talk inspiration, progression, and fashions post-lockdown mood.

We dont really work with a moodboard or references, [were] more designing the collections as a continuation of the previous one an evolution not a revolution. Its about perfecting and evolving the garments from one season to the next.

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Its An Evolution Not A Revolution: Matthew Williams On Taking His Alyx Vision To Stromboli - British Vogue

Let me introduce you to Ophiojura, a bizarre deep-sea animal found in 2011 by scientists from the French Natural History Museum, while trawling the summit of a secluded seamount called Banc Durand, 500 metres below the waves and 200 kilometres east of New Caledonia in the southwest Pacific Ocean.

Ophiojura is a type of brittle star, which are distant cousins of starfish, with snake-like arms radiating from their bodies, that live on sea floors around the globe.

Being an expert in deep-sea animals, I knew at a glance that this one was special when I first saw it in 2015. The eight arms, each 10 centimetres long and armed with rows of hooks and spines. And the teeth! A microscopic scan revealed bristling rows of sharp teeth lining every jaw, which I reckon are used to snare and shred its prey.

(J. Black/University of Melbourne, Author provided)

Bristling teeth poke out from all eight jaws, ready to pierce and shred prey. The colour in this micro-CT scan reflects the density of the skeleton.

As my colleagues and I now report in Proceedings of the Royal Society B, Ophiojura does indeed represent a totally unique and previously undescribed type of animal. It is one of a kind the last known species of an ancient lineage, like the coelacanth or the tuatara.

We compared DNA from a range of different marine species, and concluded that Ophiojura is separated from its nearest living brittle star relatives by about 180 million years of evolution. This means their most recent common ancestor lived during the Triassic or early Jurassic period, when dinosaurs were just getting going.

Since then, Ophiojura's ancestors continued to evolve, leading ultimately to the situation today, in which it is the only known survivor from an evolutionary lineage stretching back 180 million years.

Amazingly, we have found small fossil bones that look similar to our new species in Jurassic (180 million-year-old) rocks from northern France, which is further evidence of their ancient origin.

Scientists used to call animals like Ophiojura living fossils", but this isn't quite right. Living organisms don't stay frozen in time for millions of years without changing at all. The ancestors of Ophiojura would have continued evolving, in admittedly very subtle ways, over the past 180 million years.

Perhaps a more accurate way to describe these evolutionary loners is with the term paleo-endemics" representatives of a formerly widespread branch of life that is now restricted to just a few small areas and maybe just a single solitary species.

For seafloor life, the centre of palaeo-endemism is on continental margins and seamounts in tropical waters between 200 metres and 1,000 metres deep. This is where we find the relicts" of ancient marine life species that have persisted in a relatively primitive form for millions of years.

Seamounts, like the one on which Ophiojura was found, are usually submerged volcanoes that were born millions of years ago. Lava oozes or belches from vents in the seafloor, continually adding layers of basalt rock to the volcano's summit like layers of icing on a cake. The volcano can eventually rise above the sea surface, forming an island volcano such as those in Hawaii, sometimes with coral reefs circling its shoreline.

But eventually the volcano dies, the rock chills, and the heavy basalt causes the seamount to sink into the relatively soft oceanic crust. Given enough time, the seamount will subside hundreds or even thousands of metres below sea level and gradually become covered again in deep-sea fauna. Its sunlit past is remembered in rock as a layer of fossilised reef animals around the summit.

While our new species is from the southwest Pacific, seamounts occur worldwide and we are just beginning to explore those in other oceans. In July and August, I will lead a 45-day voyage of exploration on Australia's oceanic research vessel, the RV Investigator, to seamounts around Christmas and Cocos (Keeling) Islands in the eastern Indian Ocean.

These seamounts are ancient - up to 100 million years old and almost totally unexplored. We are truly excited at what we may find.

Seamounts are special places in the deep-sea world. Currents swirl around them, bringing nutrients from the depths or trapping plankton from above, which feeds the growth of spectacular fan corals, sea whips, and glass sponges. These in turn host numerous other deep-sea animals. But these fascinating communities are vulnerable to human activities such as deep-sea trawling and mining for precious minerals.

(S. Samadi/MNHN/KANADEEP2, Author provided)

The Australian government recently announced a process to create new marine parks in the Christmas and Cocos (Keeling) regions. Our voyage will provide the data required to manage these parks into the future.

The New Caledonian government has also created a marine park in offshore areas around these islands, including the Durand seamount. These marine parks are beacons of progress in the global drive for better environmental stewardship of our oceans. Who knows what weird and wonderful treasures of the deep are yet to be discovered.

Tim O'Hara, Senior Curator of Marine Invertebrates, Museums Victoria

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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This deep-sea brittle star survived 180 million years of evolution - Big Think