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Category Archives: Cbd Oil

I was a National Champion with the Florida Gators and played in NFL now I run my own CBD oil business… – The US Sun

Posted: August 26, 2023 at 4:07 am

AFTER winning two National Championships and spending six seasons in the NFL, a former Florida Gator has kickstarted his own business.

One of the stars of the long-awaited Netflix Untold docuseries on Urban Meyers' Florida Gators, titled Swamp Kings, former linebacker Brandon Spikes has lived a remarkably varied post-NFL life.

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Originally from North Carolina, football offered Spikes a path toward a brighter future.

In the documentary, Spikes discussed his tough childhood, explaining how "Football was my way out. Out of it all."

In 2006 he headed for Florida, joining a Gators program that was on the rise under their young head coach.

Spikes went on to solidify himself as a legend down in Gainesville, winning two BCS National Championships while being named a Consensus All-American twice, and an All-SEC First-Teamer three times.

Come 2010, it was time for Spikes to take the next step, ultimately being selected in the second round of the NFL Draft by the New England Patriots.

He spent four seasons with the Patriots, starting 39 of his 51 appearances, racking up 286 tackles, twelve defended passes, and four forced fumbles.

In 2014, Spikes headed for the Buffalo Bills where he'd go on to play in all sixteen games that season, starting ten.

He subsequently returned to New England, although this proved to be an ill-fated move as he was released less than a month later after running into trouble with the law.

Spikes eventually pled guilty to having left the scene of an accident, as per The Athletic, and went on to miss the 2015 season.

The following year, while working as a certified credit investor, he reached out to his former head coach Bill Belichick for help.

"I wanted to give up. I really did until I reached out to Bill," he told The Athletic.

"I reached out to everybody, people I trusted and loved, and they just couldn't give me an answer why I wasn't in the league.

"So I was like, 'F**k it, I'm about to call Bill.' So I called Bill Belichick, and of course, he answered on the first ring."

Belichick put Spikes in touch with an agent, David Canter, who managed to get him a one-year deal back in Buffalo.

Eleven appearances later, and his time in the NFL came to an end.

Spikes' next career venture took him to Canter's agency where he worked for the post-career affairs department.

Meanwhile, he also founded SpikesCBDX, which produces CBD-infused creams, oils, and gels.

"Throughout my career in the NFL, I always wanted to help myself and other athletes avoid injuries and recover quickly, without medications and their side effects," Spikes wrote on their website.

"This was the driver behind the Spikes CBDX product line, creating products all athletes could benefit from."

Fast forward to 2023, and Spikes has gone on to enter a new chapter of his post-NFL career, as a student assistant coach for the Gators.

Speaking to FloridaGators.com, he explained: "I just want to bring value and basically get this thing back to how we left it. I've seen how it should be done.

"You don't come to Florida to be mediocre. The bar is set, and I will do everything in my power to enforce what is set here."

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I was a National Champion with the Florida Gators and played in NFL now I run my own CBD oil business... - The US Sun

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The ABCs of CBD: Cannabinoids in Dermatology and Skin Care – Dermatology Times

Posted: at 4:07 am

Cannabinoids (CBDs) are gaining popularity in both the skin care industry and the dermatology drug market and are becoming increasingly available to physicians and consumers. Cannabis-based personal care products suddenly seem ubiquitous all over the market, where CBD is a featured ingredient in everything from moisturizers and lotions to makeup.1 In medical dermatology, CBD has been studied in acne, eczematous disorders, lichen planus, melanoma and nonmelanoma skin cancer, melasma, prurigo, pruritus, psoriasis, scleroderma and systemic sclerosis, and seborrheic dermatitis.2

Although some of these studies indicate a potential therapeutic benefit in skin disease, existing studies are, unfortunately, underpowered and lack rigorous design. Making matters worse, the federal government lists cannabis as a schedule I substance (defined as drugs with no currently accepted medical use and a high potential for abuse), which makes it very difficult to study CBD for medical purposes. In its last communication on CBD products in the current market, the FDA stated that the existing regulatory framework for CBD is not appropriate and that it will work with Congress to develop a safe and effective regulation strategy. Despite these issues, CBD may offer a promising new area of pharmacology for skin disease and skin care. Even if dermatology providers choose not to use or recommend these products, patients are asking about them during their office visits. Therefore, it is important to review the current evidence on CBD use in dermatology to understand its potential for treating skin diseases. It is also important to learn about the potential benefits of CBD in dermatology to better counsel patients in the office.

What Are CBDs?

CBDs are chemicals that exert their effects through cannabinoid receptors (CBRs). Multiple ligands exist for CBRs including endogenous endocannabinoids (such as AEA, 2-AG, PEA, and OEA), phytocannabinoids (produced in plants), and synthetic CBDs. The most notorious and well-known phytocannabinoid is delta-9-tetrahydrocannabinoil (THC), which is the psychoactive component of cannabis responsible for the feelings of euphoria, relaxation, heightened sensory perception, altered perception of time, and increased appetite.

Most CBDs are not psychoactive in the traditional sense. For example, many beauty products contain hempseed oil (cannabis sativa seed oil), which contains no THC. This is an important distinction to make because skin care products labeled cannabis can be misleading.

Not only are consumers confused on this topic, but health care providers are as well. A survey of 531 dermatologists found that 64% of respondents did not know that CBD is not psychoactive and 29% did not know that THC is psychoactive.3 Only half of the dermatologists on the Medical Advisory Board for the National Psoriasis Foundation believed that medical cannabis is safe for patients.4

CBRs have been discovered to exist on cutaneous nerve fibers, mast cells, and keratinocytes, and some evidence has shown that CBDs may directly stimulate keratinocytes and act on other important receptors such as PPAR-g (which regulates fatty acid storage and glucose metabolism).5 CBD has also been found to enhance adenosine A2A receptor activity, which downregulates hyperimmune states and decreases tissue inflammation.6

These basic science findings are encouraging and suggest that CBDs may be of benefit in a number of dermatological diseases, as well as for use in personal care products.

Cannabinoids continue to be of interest as they possess many characteristics that would seemingly make them a great fit for multiple dermatologic conditions: They are potentially anti-inflammatory, anti-pain, and anti-itch; can alter hair growth; can regulate epidermal proliferation; and can even decrease sebum production. In atopic dermatitis, acne, psoriasis, and hidradenitis suppurativa, there is a potential role for them, at least in theory, said Peter A. Lio, MD, clinical assistant professor of dermatology and pediatrics at Northwestern University Feinberg School of Medicine in Chicago, Illinois, and also the author of the article Cannabinoids in Dermatology: Hope or Hype? featured in the Journal of Cannabis and Cannabinoid Research.

CBD and Acne

The pathophysiology of acne is a permutation of follicular hyperkeratinization, microbial colonization, sebum production, and inflammation. The endocannabinoid N-arachidonoylethanolamine glycerol (AEA) has been shown to cause sebocyte apoptosis at higher levels, thus targeting one of the key pathophysiological mechanisms of acne.7 Several in-vitro studies indicate that CBD could be a possible treatment option for acne through its regulatory effects on sebum production and sebocyte proliferation.8

One key study, conducted by Olah et al, investigated the effects of CBD on sebaceous glands in vitro.9 The researchers found that AEA (a type of endocannabinoid) was able to inhibit lipogenic actions of sebaceous glands in a dose-dependent manner by inhibiting lipogenic compounds such as arachidonic acid and a mixture of linoleic acid and testosterone. CBD was also found to prevent pro-acne mediators from elevating TNF-a mRNA expression and normalize the lipopolysaccharide-induced expression of IL-1 and IL-6. Furthermore, in a small, split-face study, male subjects applied 3% cannabis seed extract cream to 1 side of their face twice daily for 12 weeks. At the end of the study, researchers found skin sebum production and erythema were significantly decreased compared with placebo, with no notable adverse effects.10

Although larger-scale human studies and randomized, controlled clinical trials are needed in the treatment of acne with CBDs, these preliminary studies show promise in the use of CBD as an individual or adjunctive therapy for acne vulgaris. This may prove popular with patients who are seeking alternative, complementary, or natural therapies.

CBD and Atopic Dermatitis/Eczema

CBDs have been studied for the treatment of eczema and atopic dermatitis, which affects about 10% of the US population.11 Eberlein et al studied more than 2000 eczema patients in a large, multinational cohort study and found that applying a cream containing palmitoylethanolamide (PEA) resulted in a significant reduction in dryness, excoriation, pruritus, and erythema across the population. Impressively, 56% of patients stopped using topical corticosteroids by the end of the study.12 It is important to note that this study lacked a placebo group. Therefore, it is difficult to ascertain the therapeutic benefit of the PEA vs the emollient effect of the vehicle. Nevertheless, this study is promising for the use of PEA in the treatment of eczema, as another randomized, double-blind, comparative trial of 60 patients with eczema found that PEA/AEA emollient was associated with improved scaling, dryness, and itching at day 28 of therapy.13

Oral CBD has also been studied for this inflammatory skin disease. Callaway et al found that oral hempseed oil improved AD in a randomized crossover study demonstrating a significant decrease in skin dryness, itchiness, and use of topical medications compared with olive oil.14

CBD: Emollients and Skin Care

CBD has been gaining popularity as a cosmetic material because of its reported emollient and anti-inflammatory properties. Through an examination of online search trends, a 2019 study found that consumer interest greatly increased in topical CBD products from 2015 through 2019.15 CBD has been shown to increase dermal water content and skin turgor.16 CVS.com lists nearly 50 personal care products with CBD, including muscle relief creams, moisturizers, massage oils, facial cleansers, facial masks, antiwrinkle creams, bath salts, and eye serums.17 Sephora.com lists a $125 full-spectrum CBD luxury beauty serum, whose description states that whole plant cannabis molecules penetrate quickly to visibly calm redness, clear blemishes, and deeply restore.18

Research may support its use here, as well. A mouse model investigating the emollient effect of CBD found that a 1% CBD solution applied to the skin increased the dermal water content through upregulation of aquaporin-3.19 An in vitro study using normal human epidermal keratinocytes found that CBD is able to penetrate keratinocytes and reduce the oxidative stress caused by UVB irradiation and hydrogen peroxide.8

An ideal property of a moisturizer is to treat the pruritus associated with xerosis, and multiple studies have found that anandamide, an endocannabinoid, possesses antipruritic properties via inhibition of TRPV1 (an ion channel expressed mainly in nociceptive neurons of the peripheral nervous system).20

Future Directions

CBD represents an exciting area of pharmacology in the treatment of skin disease and for use in skin care and cosmetics products. CBD has been studied for the treatment of eczematous eruptions, skin cancer, pruritus, fibrotic skin diseases, acne, seborrheic dermatitis, psoriasis, and skin rejuvenation.20 However, most studies are either in vitro studies or clinical studies with only a small number of patients. Currently, double-blind, randomized, placebo-controlled clinical trials for the use of CBD in dermatology are lacking. Preliminary studies show potential benefits but more, well-conducted trials are needed before we can offer definitive recommendations to patients. It is certainly possible that formulations of cannabinoids can be highly effective, and I remain cautiously optimistic about this. However, that means for nowwe are in a tough place and are not really able to recommend cannabinoid products routinely, in my opinion, Lio concluded.

References

1. Nickles MA, Lio PA. Cannabinoids in dermatology: hope or hype? Cannabis Cannabinoid Res. 2020;5(4):279-282. doi:10.1089/can.2019.0097

2. Mounessa JS, Siegel JA, Dunnick CA, Dellavalle RP. The role of cannabinoids in dermatology. J Am Acad Dermatol. 2017;77(1):188-190. doi:10.1016/j.jaad.2017.02.056

3. Robinson E, Murphy E, Friedman A. Knowledge, attitudes, and perceptions of cannabinoids in the dermatology community. J Drugs Dermatol. 2018;17(12):1273-1278.

4. Nussbaum D, Desai S, Gonzalez-Lopez A, Hawkes JE, Gondo G, Friedman A. Practices and perspectives on medical cannabis and cannabinoids: a survey of the National Psoriasis Foundation Medical Advisory Board. JAAD Int. 2022;9:23-25. doi:10.1016/j.jdin.2022.07.001

5. Gaffal E, Cron M, Glodde N, Tting T. Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors. Allergy. 2013;68(8):994-1000. doi:10.1111/all.12183

6. Burstein S. Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorg Med Chem. 2015;23(7):1377-1385. doi:10.1016/j.bmc.2015.01.059

7. Dobrosi N, Tth BI, Nagy G, et al. Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling. FASEB J. 2008;22(10):3685-3695. doi:10.1096/fj.07-104877

8. Baswan SM, Klosner AE, Glynn K, et al. Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clin Cosmet Investig Dermatol. 2020;13:927-942. doi:10.2147/CCID.S286411

9. Olh A, Tth BI, Borbr I, et al. Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. J Clin Invest. 2014;124(9):3713-3724. doi:10.1172/JCI64628

10. Ali A, Akhtar N. The safety and efficacy of 3% cannabis seeds extract cream for reduction of human cheek skin sebum and erythema content. Pak J Pharm Sci. 2015;28(4):1389-1395.

11. Eczema stats. National Eczema Association. Accessed July 9, 2023. https://nationaleczema.org/research/eczema-facts/

12. Eberlein B, Eicke C, Reinhardt HW, Ring J. Adjuvant treatment of atopic eczema: assessment of an emollient containing N-palmitoylethanolamine (ATOPA study). J Eur Acad Dermatol Venereol. 2008;22(1):73-82. doi:10.1111/j.1468-3083.2007.02351.x

13. Yuan C, Wang XM, Guichard A, et al. N-palmitoylethanolamine and N-acetylethanolamine are effective in asteatotic eczema: results of a randomized, double-blind, controlled study in 60 patients. Clin Interv Aging. 2014;9:1163-1169. doi:10.2147/CIA.S65448

14. Callaway J, Schwab U, Harvima I, et al. Efficacy of dietary hempseed oil in patients with atopic dermatitis. J Dermatol Treat. 2005;16(2):87-94. doi:10.1080/09546630510035832

15. Wang JV, Shah S, Albornoz CA, Saedi N. Consumer interest in topical cannabidiol: an examination of online search trends from 2015 to 2019. Clin Dermatol. 2021;39(6):1014-1017. doi:10.1016/j.clindermatol.2020.11.007

16. Palmieri B, Laurino C, Vadal M. A therapeutic effect of CBD-enriched ointment in inflammatory skin diseases and cutaneous scars. Clin Ter. 2019;170(2):e93-e99. doi:10.7417/CT.2019.2116

17. CBD products. CVS. Accessed July 9, 2023. https://www.cvs.com/shop/personal-care/cbd

18. Saint Jane Beauty Luxury Beauty Serum Calming Treatment. Sephora. Accessed July 9, 2023. https://www.sephora.com/product/luxury-beauty-serum-P444222

19. Ikarashi N, Shiseki M, Yoshida R, et al. Cannabidiol application increases cutaneous aquaporin-3 and exerts a skin moisturizing effect. Pharmaceuticals (Basel). 2021;14(9):879. doi:10.3390/ph14090879

20. Sheriff T, Lin MJ, Dubin D, Khorasani H. The potential role of cannabinoids in dermatology. J Dermatol Treat. 2020;31(8):839-845. doi:10.1080/09546634.2019.1675854

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The ABCs of CBD: Cannabinoids in Dermatology and Skin Care - Dermatology Times

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Exploring the Connection: Does CBD Help with Depression and How? – babyboomers.com

Posted: at 4:07 am

In our fast-paced modern world, the spotlight on mental health and overall well-being is shining brighter than ever. Among the intriguing topics of discussion, CBD's potential role in easing symptoms of various disorders has captured significant attention. A burning question that's on the minds of many is: Can CBD really make a difference in managing depression? In this comprehensive guide, we're embarking on a journey to explore the potential link between CBD and depression. We'll dive into ongoing research, hear from those who've experienced it firsthand, and uncover how CBD might offer a helping hand to those facing the challenges of this pervasive mental health battle.

Depression isn't just a fleeting sense of unhappiness or letdown. It's a sophisticated mental health condition that has the power to impact every aspect of a person's life. Symptoms span a wide spectrum from persistent feelings of sadness and fatigue to a waning interest in activities that once sparked joy. In more severe cases, it can even lead to distressing thoughts of self-harm.

In the pursuit of effective treatments, researchers and healthcare experts are continuously seeking better ways to combat this multifaceted challenge. As a result, alternative remedies like CBD for depression have been gaining traction.

CBD, often referred to as cannabidiol, is a natural compound extracted from the cannabis plant. While it shares a connection with THC the compound responsible for that euphoric sensation CBD doesn't deliver the same intoxicating effects. Instead, it engages in a friendly chat with our body's endocannabinoid system, a complex network that orchestrates various bodily functions.

The intrigue around CBD's potential to help with depression stems from its interaction with this system. However, as with any exciting prospect, it's vital to delve into the research, step by step, before jumping to any conclusions. The journey of understanding CBD's role in managing depression is a thorough and evolving one.

The mechanisms through which CBD might address depression are diverse and still a subject of ongoing research. Experts have highlighted several potential avenues in which CBD could influence depression symptoms, emphasizing the need for further exploration into how exactly it might help.

The endocannabinoid system (ECS) plays a role in mood regulation and emotional responses. CBD is believed to interact with ECS receptors, potentially influencing the release of neurotransmitters associated with mood. By modulating the ECS, CBD might contribute to a sense of balance and well-being.

Imbalances in neurotransmitters, such as serotonin and dopamine, are implicated in depression. Some studies suggest that CBD may impact these neurotransmitter systems, potentially promoting a more stable mood. However, the exact mechanisms are still under investigation.

Chronic inflammation has been linked to various mental health conditions, including depression. CBD has demonstrated anti-inflammatory properties in preclinical studies, leading researchers to speculate that its anti-inflammatory effects might contribute to its potential as an antidepressant agent.

While the potential mechanisms of CBD for depression are intriguing, it's essential to evaluate the scientific evidence through a critical lens.

Numerous preclinical studies using animal models have explored the effects of CBD on depression-like behaviors. These studies have shown promising results, suggesting that CBD might exhibit antidepressant effects by modulating neurotransmitter systems and reducing stress-related responses. However, translating these findings from animal models to human experiences is a complex process that requires further investigation.

Human research on CBD's effects on depression is still in its early stages, but initial findings are encouraging. Some small-scale clinical trials and observational studies have suggested that CBD may help alleviate symptoms of depression. However, more rigorous research with larger sample sizes and placebo-controlled designs is needed to draw definitive conclusions.

Before considering CBD as a potential treatment for depression, it's crucial to keep certain considerations and precautions in mind.

If you or a loved one is considering using CBD for depression, it's imperative to consult a qualified healthcare professional. A mental health provider can assess your individual circumstances, discuss potential risks and benefits, and help you make an informed decision. CBD should not be used as a substitute for evidence-based treatments, and its use should be integrated into a comprehensive mental health strategy.

Not all CBD products are created equal. When selecting a CBD product, consider factors such as the source of CBD (hemp-derived CBD is preferable), third-party lab testing, and the presence of other ingredients. Reputable manufacturers provide transparency about their products' potency and purity.

CBD is generally well-tolerated, but some individuals may experience side effects. These can include dry mouth, changes in appetite, diarrhea, and fatigue. It's essential to start with a low dose and monitor your body's response. If you experience any adverse effects, discontinue use and consult a healthcare professional.

One of the most popular methods, CBD oil or tinctures, can be taken sublingually (under the tongue) for quick absorption. They're available in various concentrations, allowing users to adjust the dosage based on their needs.

For those who prefer a more traditional method, edibles, and capsules provide a convenient way to consume CBD. Do note that these methods might take longer to manifest effects due to the digestion process.

While more commonly used for pain or skin conditions, some individuals opt for CBD-infused creams or balms, applying them to specific areas for localized relief.

Starting with a low dose and gradually increasing is typically advised. Monitoring effects and maintaining consistency can be pivotal in determining if CBD is a beneficial adjunctive treatment.

So, does CBD help with depression? This question is one that continues to intrigue researchers, clinicians, and individuals seeking alternative approaches to mental health. While preliminary evidence suggests that CBD may hold potential as an adjunctive treatment for depression, more rigorous research is needed to establish its effectiveness and safety. If you or a loved one is considering CBD for depression, consultation with a healthcare professional is essential. As science advances and our understanding deepens, CBD's role in the realm of mental health may become clearer, offering new possibilities for those seeking relief from the burdens of depression.

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Exploring the Connection: Does CBD Help with Depression and How? - babyboomers.com

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Hulk Hogan reveals why he quit drinking alcohol – Yahoo Eurosport UK

Posted: at 4:07 am

Hulk Hogan has opened up about his decision to become sober.

The retired WWE wrestler recently spoke to Muscle and Health, telling the publication that after decades of drinking, he's finally "done".

"I've had a lot of practice drinking because I wrestled for about forty years, so those guys have a beer every once in a while," the 70-year-old star shared. "But about seven months ago, I decided not to drink any more alcohol. I was at a New Year's Eve party and saw a bunch of stuff that I didn't condone or like. I saw myself in this environment, and I went, 'You know what? I don't know how I got here, but I'm done.' It was just that one thing."

"It feels much better to be so clear-headed," the WWE Hall of Famer continued. "I'm no longer tempted to drink alcohol. I don't have an addictive personality. I mean, with anything. It can be business or people or alcohol or drugs. When I'm done, I'm done."

The former wrestler revealed he now favours CBD (cannabidiol oil), which he was introduced to by Ric Flair and Mike Tyson.

"It took me a while to figure it out because I am a little slow," he explained of using the substance. "I had to do a lot of research and do my due diligence," before adding, "I figured this was something that really would benefit a lot of people that needed help - and I know it will."

He added he believed CBD products could help people with their health, especially those returning from war, drug addicts, or "people who've got themselves into the prescription trap following illness or anxiety".

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Best Male Enhancement Gummies 2023: Compare the Top-Rated … – Kirkland Reporter

Posted: at 4:07 am

It is high time men start to pay attention to their well-being. We say this because men tend to ignore their overall health more than women because they hesitate to talk about it. They can start by taking supplements that can support sexual function and overall performance in their body.

Many products claim to boost the health of your penis and reproductive system. The latest product that can boost your libido is male enhancement gummies or CBD gummies.

Our research and editorial team ranked the best male enhancement gummies that can provide multiple health benefits and even help treat erectile dysfunction and premature ejaculation. Any supplement from this list may improve your sex life and health.

We found the best male enhancement gummies that can boost your sexual performance and overall well-being to a great extent. We considered many factors while preparing this list, and only the most suitable products made our list.

Any male enhancement supplement you pick from here can improve blood flow to the penis. You can spice up your sex life and perform better in the bedroom.

Since all these male enhancement products are made from natural ingredients, they dont have any side effects on your body.

Before taking a detailed look at the best male enhancement gummies, go through their summary in the following table for a quick read.

A well-known brand in the industry has developed this male enhancement supplement. Unabis Passion Gummies are formed of natural components that can improve your sexual function to a great extent.

This natural product has 15 mg full-spectrum CBD oil extract, horny goat weed, and a delicious cola flavor to enhance your sexual desire. Unabis Passion Gummies can help improve blood flow to the penis of individuals with low libido.

These CBD gummies can enhance your sexual performance by balancing your testosterone production and improving your erection quality so that you enjoy better orgasms.

If you are looking for male enhancement gummies from a reputable brand, Xwerks Rise is the ideal choice. This supplement can help boost blood flow to the penis and reproductive system to enjoy several male health benefits.

This male enhancement supplement contains boron, zinc, shilajit, Tongkat Ali, and other proven ingredients to improve the health of your penile chambers so that your sexual function improves on its own.

These gummies can increase testosterone production and help improve your sex life. They can help reduce stress, improve energy levels, and restore youthful stamina.

Elm & Rye produces a host of male enhancement products and CBD gummies to help people with low testosterone levels. Its libido gummies are formulated with organic ingredients like Muira Puama, Tribulus Terrestris, Ginseng, Maca root, and others to improve your sexual function.

Elm & Rye Libido Gummies also comprise L-arginine, an amino acid that can fight erectile dysfunction and premature ejaculation. This male enhancement supplement boosts testosterone levels and overall male health.

You can enjoy better performance in the bedroom as Elm & Rye Libido Gummies relax the blood vessels to increase circulation.

Boner Bears ME Gummies are not CBD gummies, but when taken one hour before sex have been proven to improve sexual function. No one except the manufacturer of this supplement knows what goes inside these gummies. It is said on the official website that this male enhancement supplement uses a blend of nitric oxide activators and PDE5 inhibitors.

From our prior knowledge, nitric oxide has been proven to improve blood flow to the penis and provide multiple health benefits. It can supercharge energy levels and positively impact your overall health.

These gummies can help target the root cause of poor sexual well-being and boost testosterone to enhance male health.

Dame Desire Gummies may boost your sexual function with the help of natural ingredients like Ashwagandha and L-theanine, which are rich in vitamins and other compounds that enhance sexual performance in men.

Dame Desire Gummies can boost testosterone levels and reduce stress so that you can enjoy better sexual function. This supplement can relax the blood vessels in the penis so that you get rid of sexual issues like erectile dysfunction.

These gummies are not CBD gummies as well.

Maude Libido Gummies are non-CBD, rich in organic ingredients like pine pollen and Tribulus Terrestris that have been proven effective in boosting blood flow to the penis and increasing libido in men.

Maude Libido Gummies can significantly improve virility and sexual function with the help of proven ingredients. They can supply energy to your body so you can enjoy sex with your partner. These gummies can also improve your sperm count.

These are one of the best male enhancement CBD gummies on our list. House of Wise Sex Gummies helps in improving sexual function using science-backed ingredients. This supplement has been proven to improve libido and sexual desire in men by boosting blood flow to the sex organs.

The ingredients used in these CBD gummies can help provide multiple health benefits that can enhance your well-being without inducing any side effects. This supplement can improve testosterone production and even help treat erectile dysfunction.

Blue Moon Hemp Love Bears can boost testosterone levels and sexual function using an all-natural blend of effective ingredients. It uses an amino acid, L-arginine, that is extremely helpful in improving your sexual health.

All the natural ingredients that go into the formula of this supplement are derived from trusted sources to protect your overall health.

Love Bites uses L-citrulline, horny goat weed, maca root, and other ingredients to improve sexual performance in men. These ingredients can improve blood flow to the penis and enhance testosterone production. They are packed with multiple benefits for male health.

Experience improved sexual function and sexual desire with the help of Love Bites.

Force Factor Horny Goat Weed Gummies are non-CBD that help in boosting your sexual function by increasing your testosterone levels. It uses traditional medicine to improve mens blood flow and sperm count, so they experience better orgasms and well-being.

Regular consumption of this male enhancement supplement can significantly impact your love life.

Force Factor Test X180 Gummies uses Tribulus Terrestris, fenugreek, horny goat weed, etc., to enhance your sex drive and improve your sexual health. This supplement can enhance testosterone production, which may help improve overall health.

Force Factor Test X180 Gummies can also improve your mental health.

Solterra Mars Mens Fertility Gummies are packed with sexual benefits for the male body. It can improve your sex drive so sexual function increases. These non-CBD gummies can enhance your sex life using proven ingredients.

All the ingredients that go into the formula of this supplement have been proven to enhance sexual function by boosting testosterone.

Choosing the most effective male enhancement gummies is challenging because there are so many options on the market. Our team considered several ranking factors while selecting these CBD gummies.

All the male enhancement products on our list have been proven to provide several health benefits to people with low libido and poor penis health. They can help people with zinc deficiency by improving their sexual desire and overall performance in bed.

Lets look at the ranking factors in detail to understand how male enhancement or CBD gummies entered this exclusive list.

It is essential to pick male enhancement products with natural ingredients so they dont cause harmful side effects on your body. You can experience enhanced sexual health and sex drive if you consume proven natural products without putting your body at risk.

Core Ingredients like L-arginine, L-citrulline, Tribulus Terrestris (traditional medicine), Muira Puama, pine pollen, and other amino acids can help people with zinc deficiency experience improved sexual function. These ingredients can boost blood flow to the penile chambers so your penis can maintain good erection quality.

The absence of artificial sweeteners from these CBD gummies enables them to increase testosterone levels effectively.

We only selected male enhancement or CBD gummies whose makers were honest about the formula of their products. People need to know about a supplements composition before they consume it.

When makers are transparent about their manufacturing practices, it increases the trust of individuals in their products. It helps people believe that a particular male enhancement supplement can boost their sexual function, sex drive, and overall health.

Many brands go overboard with the benefits of their male enhancement or CBD gummies. Some even claim that their supplement can increase penis size or penis length. There might be various benefits of consuming a male enhancement supplement, but it is nearly impossible to make this happen.

Every supplement on this list makes realistic promises like improving libido, erection quality, overall sexual health, and other benefits.

If you decide to consume a supplement daily for the next few months, you must get accustomed to its taste and flavor. We chose only those male enhancement or CBD gummies that used natural flavors and had an impeccable taste. These gummies can improve your sex drive, sexual function, and penis health.

Most men prefer tasty and well-textured gummies with zero side effects and a well-rounded effect on your well-being.

Another factor that comes into the picture while selecting any supplement for this list is the manufacturers reputation in the USA and other countries. All the brands on this list have a solid reputation in the industry because of their transparent manufacturing practices and dealings.

Their male enhancement products can improve your sex life and boost libido, providing other benefits and negligible side effects.

We ensure that all the chosen male enhancement or CBD gummies fulfill the industry standards of purity. Almost every supplement on this list is produced in a clean and approved facility under the strictest sterile standards.

Using traditional medicine like Muira Puama and amino acids like L-arginine and L-citrulline reduces the chances of getting side effects.

These male enhancements or CBD gummies can improve your libido and testosterone levels without compromising your well-being due to their clean and safe manufacturing process.

Our research team went through several male enhancement reviews online to get a clearer picture of the CBD gummies included in this list. People posted positive feedback about every supplement here and how it helped them experience better sexual function, sex drive, and penis health.

Basing the list on customer reviews is important because it helps us to find out the real benefits of male enhancement or CBD gummies on the body.

Another important factor while picking any supplement for this list is determining whether a 100% satisfaction guarantee backs it. People nowadays want a money-back guarantee for at least 60 days to determine whether the supplement is ideal for them.

If the supplement fails to improve your testosterone levels or sex life, you should have the option of returning it to the makers for a refund.

Men need to make genuine efforts to improve their sexual health naturally. Sure, they can take male enhancement supplements to boost their testosterone and libido, but they need to do a couple of other things to improve their overall sexual performance.

Some natural ways with negligible side effects can help maintain male vitality. They can help you improve penis health to experience better sexual arousal and sex life.

Lets see how you can improve your testosterone with the help of these science-backed ways.

It is a known secret that junk and processed food items are unhealthy for your testosterone levels. These food items can interfere with blood flow and harm your overall well-being.

You can make many diet changes to help enhance your sexual function by boosting testosterone and sex drive. Various scientific studies have shown that green leafy vegetables, black tea, and legumes can help keep your penile size and testosterone level intact.

There are many benefits of exercising daily. One of them is experiencing improved testosterone in the body. When you exercise regularly, the blood flow in your body improves, and your sex drive increases to a great extent. People with low libido and poor erection quality can benefit significantly from physical activities.

You can experience better performance in the bedroom with your partner with enhanced testosterone production.

Stress can take away the most precious moments of your life by interfering with your testosterone levels. It is essential to reduce stress if you want to enjoy your sex life. Although the male enhancement supplements on this list can reduce anxiety in men, you need to try other natural ways of reducing stress.

For instance, you can avoid stress triggers that result in low testosterone. You can also take help from women who practice yoga and meditation to reduce stress and anxiety.

Your body balances hormone production when you are asleep. Many men who dont take sufficient sleep suffer from decreased sex drive. Poor sleeping patterns have been found to affect libido and sexual health in both men and women.

You can take a sleep-boosting supplement to help you fall asleep and promote deep sleep. It can help increase testosterone levels in your body significantly.

It is a very debatable topic in the world of male enhancement products.

Many men have erectile dysfunction because of zinc deficiency. Male enhancement or CBD gummies with zinc and other compounds can help prevent erectile dysfunction.

Many products aim to treat this problem by boosting your sexual function and improving your erection quality. These gummies improve blood flow to the penis and reproductive system to increase testosterone levels and sex drive.

You can enjoy a happier sex life with your partner by eliminating sexual issues.

Unlike other supplements with harmful steroids and artificial substances, we have only included natural male enhancement CBD gummies free from harmful ingredients. These products do not contain artificial sweeteners, flavors, or stimulants that can interfere with other aspects of your health and induce harmful side effects.

Instead, they are formed of organic ingredients and natural extracts that can improve your sexual function and spice up your sex life. These male enhancement products benefit your body by increasing blood flow to the penis and treating erectile dysfunction.

All the sexual wellness products listed here are free from significant side effects. They are beneficial for male health as they boost testosterone extensively.

However safe these male enhancement CBD gummies might be, any person with a medical condition, pregnant women, and children must not consume them without professional medical advice.

It is widely known that men are experiencing a wide range of sexual health issues due to many factors with every passing day. This has affected their penis length and penis size extensively.

Therefore, it has become all the more critical for them to take male-enhancement CBD gummies to boost their libido and enhance their sexual function. Choose from any of the best male enhancement gummies above to increase testosterone levels and improve your well-being.

All the products listed here have been carefully chosen after going through many male enhancement reviews online. You can highly benefit from these products if you also suffer from poor testosterone and declining male well-being.

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Best Male Enhancement Gummies 2023: Compare the Top-Rated ... - Kirkland Reporter

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‘We are all we have’: CBD business struggles – The Bay’s News First – SunLive

Posted: at 4:07 am

When the night is done at her familys Turkish restaurant Seyda Coskun goes home, washes off the kebab oil from her shift and frets. Its like this most nights and has been for some time.

As one of the remaining stores on Downtown Taurangas Devonport Rd, this is the harsh reality for those trying to make ends meet with a struggling business in a cost of living crisis.

While all passer-bys might see are shopfronts among For Lease signs, and construction sites there are whole worlds of financial stress, waning hope and family burdens that toil within these businesses.

Turkish restaurant and family business Abrakebabra opened in 2008 on Devonport Rd.

Abrakebabras manager Seyda Coskun says: Back then the street was a lot more profitable.

We actually existed back then. Years ago the environment was a lot more lifted. It was happy and people were more willing to spend money.

Seyda Coskun, Hayati Gurleyen and Hatice Saribuga Gurleyen of struggling family business, Abrakebabra on Devonport Rd. Photo: Bob Tulloch.

More hours, no paychecks

Now, the business is taking it week-by-week. Seyda says the businesses is struggling with a lack of customers due to ongoing construction sites and lack of CBD parking.

Our family is working far more hours and were not taking home pay cheques anymore because our staff need the pay cheques.

She says restaurant losses are 40-45 per cent some weeks. With financial stresses and personal bills to pay, Seyda says its impossible to switch off from the business.

It never goes awaymost nights Im just worrying because its a family business and it means a lot more than just working for another company. We are all we have. You go home, take a shower, and you wash all the oil and the kebab off you and just worry. Its awful.

Construction continues

Ongoing construction work on Devonport Rd and Elizabeth St is a huge problem for downtown businesses, says Seyda.

Were not getting any notices when parts of the road are all blocked off. There is no compensation available...so were out of pocket.

Devonport Rds construction sites include private developments and council projects. Tauranga City Councils future office block at 90 Devonport Rd is expected to be complete early-2025.

Seyda says it would help customer foot traffic if construction work took a staggered approach.

Itd be great if they could tackle one part of the city first, even one half of the street, then the other.

While we will try to mitigate disruption where we can, we do need to balance it with making sure the transformation can take place as quickly as possible so we can get the heart of our city pumping again and local businesses can start benefiting from that," says Tauranga City Council's general manager of city development and partnerships Gareth Wallis.

Carpark spots and costs

Seyda says the CBD parking situation is also damning business on both customer and staff fronts.

If customers can even find a park, theres then the parking charges themselves and theyre quite expensive. Cost of living as you know is going up. Our staff are leaving because they cant one, find a park; and if they can its too expensive which is just damning all of our businesses again.

Gareth says TCC has been closely tracking city centre parking availability.

Recent data from June 2023 shows, on average, only 50-60 per cent of on-street carparks are being used Monday-Friday. In parking buildings, during peak hours, no more than 70 per cent of carparks are used at any given time.

Short-term plans are also progressing to develop a temporary carpark at 160-176 Devonport Road."

Business strategy

Tauranga Business Chamber CEO Matt Cowley met with struggling downtown businesses last week.

Some businesses need help with business strategy to diversify their revenue sources, some need help with cash flow forecasting as their liquidity run-way is month-to-month, others need help renegotiating leases with landlords. The two most common issues are worsening lack of parking and the growing antisocial behaviour.

Seyda says antisocial behaviour in the CBD, making customers and staff feel unsafe, isnt helping business either.

So is there enough support for these CBD stores who have been in our community for years? Matt says if youre city centre business, the answer is: No.

If youre a ratepayer in other parts of Tauranga whod be paying for the support, then maybe. Ultimately, if you ask a CBD business owner what support they want the most, its more carparking.

Gareth says council has been implementing several short to medium term solutions to support local businesses at this time, through the City Centre Development Incentive Fund.

Some of these initiatives include: partnering with Tauranga Business Chamber to provide free targeted support and mentoring to each businesss unique situation; and funded access to the Business Navigator programme managed by Mentoring NZ to ensure city centre businesses have expert advice and resources to get through this period of development," says Gareth.

"The unfortunate part of that is that it takes us away from the business and we cant leave the business theres just no staff so it makes it a bit tougher on families," says Seyda, in regards to business mentoring support.

"I appreciate it takes time to do anything. I just think they [TCC] need to appreciate weve already given them a lot of time and theyve caused us nothing but worry. No reassurance. No support. No real change.

Support local

Downtown Taurangas Chair Ash Gee says the community is encouraged have the Covid-19 support local mind-set towards downtown businesses.

Continue to support your favourite businesses in the city centre that may be just a little bit harder to get to presently. Community support is required to help get our city centre businesses through this transformation phase.

Abrakebabra doors remain open, while other businesses of Devonport Rd have shut up shop.

Its really sad, and its kind of a reminder that that could happen to us which is really hard driving past all the closed businesses every day. It makes you think that really could be us, and who knows in however much time. Its quite scary.

Seyda and her family have started a petition for people to support downtown businesses.

Sign the petition at: https://www.change.org/p/support-tga-city-centre

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'We are all we have': CBD business struggles - The Bay's News First - SunLive

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8 Best CBD Oils For Cats With Anxiety – mindbodygreen

Posted: June 20, 2023 at 8:42 pm

Written by

This content is produced in collaboration with an advertising partner and follows mindbodygreens editorial guidelines. The content is written by a third party. Statements are not fact-checked by a medical expert.

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June 20, 2023

Advertorial:This content is produced by a third-party advertiser. Statements are not fact checked by a medical professional.

Disclaimer: Our website includes general information and instruction relating to health and wellness topics. This content is not a substitute for medical advice from your health care provider. All treatment decisions should be determined in partnership with a health care practitioner. Hemp CBD products are derived from U.S. industrial hemp (less than 0.3% THC) and European hemp (less than 0.2% THC). While CBD products derived from the hemp plant (Cannabis sativa) are legal on a federal level in the U.S., some states have specific laws, so you'll want to check your state's laws to be sure.

The best CBD oils for cats with anxiety

Many people struggling with anxiety have turned to CBD to help promote a sense of calmbut humans aren't the only ones who can benefit from the cannabinoid. If your cat struggles with occasional bouts of anxiousness, there's a chance that CBD oil could help support a more even mood.*

The research surrounding CBD and cats is in even earlier stages than the studies on humans. While a 2021 study1 found that CBD is generally well tolerated by healthy cats, most evidence supporting the use of CBD oils for cats with anxiety is anecdotal from pet owners or veterinarians.

What we do know about cats and CBD? Similar to humans, cat have an endocannabinoid system or ECS. This biological communication network 2 is present in all mammals, where it plays a role in supporting the balance of body systems, like the nervous and immune systems.

The ECS has an impact on pain control, digestion, and, you guessed it, mood. When you give your feline CBD, you're introducing external cannabinoids to support the endocannabinoid system, including your animal's mood. Just remember further research is still needed to understand the exact interaction between CBD and the ECSeven in humans.

If you're ready to explore the benefits of CBD oil for cats, we've compiled a list of our top picks to guide you toward the best possible option. Just remember that it is key to consult your vet before introducing a new supplement into your cat's routine.

Penguin CBD Cat Oil sources broad-spectrum hemp from pesticide-free Oregon farms for a CBD that you can feel good about giving your cat. Each bottle has just four ingredients: hemp, MCT oil, natural flavor, and terpenes (part of the hemp plant). When combined together, they offer a gentle 5mg of CBD per serving in a cat-friendly salmon flavor. Our only note? While MCT oil is a common carrier oil for CBDincluding in pet-focused formulasit's not tolerated by all furry companions.

View COAs here.

Penguin CBD Cat Oil sources broad-spectrum hemp from pesticide-free Oregon farms for a CBD that you can feel good about giving your cat. Each bottle has just four ingredients: hemp, MCT oil, natural flavor, and terpenes (part of the hemp plant). When combined together, they offer a gentle 5mg of CBD per serving in a cat-friendly salmon flavor. Our only note? While MCT oil is a common carrier oil for CBDincluding in pet-focused formulasit's not tolerated by all furry companions.

FOCL specifically formulated this non-GMO CBD oil for petsand it shows from the three pet-friendly flavors. You'll have the choice of Peanut Butter, Wild Salmon, or Savory Chicken oil, which comes in either a gentle (10mg CBD per serving) or moderate (20mg) potency. Our favorite part? These oils are actually vegan despite the flavor names.

View COAs here.

FOCL specifically formulated this non-GMO CBD oil for petsand it shows from the three pet-friendly flavors. You'll have the choice of Peanut Butter, Wild Salmon, or Savory Chicken oil, which comes in either a gentle (10mg CBD per serving) or moderate (20mg) potency. Our favorite part? These oils are actually vegan despite the flavor names.

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Cornbread Hemps pet-friendly formula uses only three ingredients: USDA certified organic hemp, organic MCT oil, and the brands proprietary vegan corn dog flavoring. Derived from top-quality hemp plants from the brands own Kentucky farms, this full-spectrum option ensures a robust combination of beneficial cannabinoids, terpenes, and other natural compounds. It does only come in one flavor and potency (17mg CBD per serving), though, but youll likely be able to customize your cats dose using the clearly marked dropper.

View COAs here.

Cornbread Hemps pet-friendly formula uses only three ingredients: USDA certified organic hemp, organic MCT oil, and the brands proprietary vegan corn dog flavoring. Derived from top-quality hemp plants from the brands own Kentucky farms, this full-spectrum option ensures a robust combination of beneficial cannabinoids, terpenes, and other natural compounds. It does only come in one flavor and potency (17mg CBD per serving), though, but youll likely be able to customize your cats dose using the clearly marked dropper.

Fewer pet oils are USDA certified organic, but this option from InnoVet is an exception. Formulated for cats and small dogs, the full-spectrum pick comes in two gentle strengths with either 4 or 8mg of CBD per serving. Not only does the oil come with a 30-day money back guarantee, but it also opts for hemp oil rather than MCT oilso you get the bonus of additional omega fatty acids in the carrier oil. While there aren't any fun flavors of this oil, the brand does also offer a hemp oil with catnip instead (if you need a little extra incentive).

View COAs here.

Fewer pet oils are USDA certified organic, but this option from InnoVet is an exception. Formulated for cats and small dogs, the full-spectrum pick comes in two gentle strengths with either 4 or 8mg of CBD per serving. Not only does the oil come with a 30-day money back guarantee, but it also opts for hemp oil rather than MCT oilso you get the bonus of additional omega fatty acids in the carrier oil. While there aren't any fun flavors of this oil, the brand does also offer a hemp oil with catnip instead (if you need a little extra incentive).

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ElleVets CBD oil is a stronger-potency option that uses a proprietary strain of full-spectrum hemp combined with CBDa or cannabidiolic acid. [The latter is believed to be even more potent than regular CBD, those further research is still needed.] If the 70mg serving of this oil seems too high for your fur-baby, it comes with a syringe to easily customize the dosage as needed. Plus, the brand even includes free capsules to help pet parents sneak the oil into their cat's favorite treat.

View COAs here.

ElleVets CBD oil is a stronger-potency option that uses a proprietary strain of full-spectrum hemp combined with CBDa or cannabidiolic acid. [The latter is believed to be even more potent than regular CBD, those further research is still needed.] If the 70mg serving of this oil seems too high for your fur-baby, it comes with a syringe to easily customize the dosage as needed. Plus, the brand even includes free capsules to help pet parents sneak the oil into their cat's favorite treat.

Science-Rite uses USA-grown, organic, broad-spectrum hemp in its cat-friendly formula. The Nano Hemp Pet Tincture comes in four different flavorsbeef, peanut butter, chicken, or salmonand is available in a wide range of strengths. The lowest, and likely the best starting point for pet parents who are new to CBD, is the lowest strength formula with 5mg of CBD per serving. It does, however, contain MCT oil as a carrier, which may or may not work for your cat.

View COAs here.

Science-Rite uses USA-grown, organic, broad-spectrum hemp in its cat-friendly formula. The Nano Hemp Pet Tincture comes in four different flavorsbeef, peanut butter, chicken, or salmonand is available in a wide range of strengths. The lowest, and likely the best starting point for pet parents who are new to CBD, is the lowest strength formula with 5mg of CBD per serving. It does, however, contain MCT oil as a carrier, which may or may not work for your cat.

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Another USDA certified organic formula, this full-spectrum tincture offer a gentle potency of 4mg of CBD per serving to promote relaxation.* Also certified by the National Animal Supplement Council (NASC), it has just two ingredients: MCT oil and hemp.

View COAs here.

Another USDA certified organic formula, this full-spectrum tincture offer a gentle potency of 4mg of CBD per serving to promote relaxation.* Also certified by the National Animal Supplement Council (NASC), it has just two ingredients: MCT oil and hemp.

One of the more affordable picks on our list, Hemp Factory Outlet sources hemp from USA farms and uses minimal ingredients in its pet-friendly formulas. While this tincture is only available in one potency, Hemp Factory Outlet provides a marked dropper and offers guidance on how to best administer to your cat based on their weight. Also worth noting: This is another unflavored oil, so you may need to get a little creative by dropping it on your cats food or treats.

View COAs here

One of the more affordable picks on our list, Hemp Factory Outlet sources hemp from USA farms and uses minimal ingredients in its pet-friendly formulas. While this tincture is only available in one potency, Hemp Factory Outlet provides a marked dropper and offers guidance on how to best administer to your cat based on their weight. Also worth noting: This is another unflavored oil, so you may need to get a little creative by dropping it on your cats food or treats.

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Product Quality and Purity

We thoroughly evaluated the quality and purity of each CBD oil for cats with anxiety. We considered factors such as the source of the CBD, whether it was derived from organic hemp plants, and whether the products underwent third-party lab testing to ensure potency, purity, and the absence of harmful contaminants.

CBD Concentration and Dosage

We examined the concentration of CBD in each oil and its suitability for cats. The optimal dosage for feline anxiety varies, so we looked for oils with clear dosage instructions and options for different cat sizes. We considered products that provided a sufficient concentration of CBD to be effective without overwhelming the cat's system.

Customer Reviews and Feedback

We paid close attention to customer reviews and feedback from cat owners who had used CBD oils for anxiety relief. Positive testimonials regarding effectiveness, ease of administration, and overall satisfaction were important factors. We also considered any negative feedback or concerns to ensure a comprehensive evaluation.

With the rising popularity of CBD for cats or dogs, it can be tricky to navigate the wide array of options available in the market. Be sure to take into account factors like the quality of ingredients, third-party lab testing, and a pet-friendly potency when making your selection. And always speak with your pet's veterinarian before adding a new supplement to their routine.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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8 Best CBD Oils For Cats With Anxiety - mindbodygreen

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CBD Oil Market to Reach USD 55,791.3 Million by 2028 | With – GlobeNewswire

Posted: at 8:42 pm

Pune, India, June 14, 2023 (GLOBE NEWSWIRE) -- The global CBD oil market size is expected to showcase considerable growth by reaching USD 55,791.3 million by 2028 while exhibiting an exceptional CAGR of 47.49% between 2023 and 2028. This information is published by Fortune Business Insights, in a report, titled CBD Oil Market, 2023-2028. The report further mentions that the market stood at USD 2,770.8 million in 2020. Factors such as the increasing product approvals by the FDA and concerned government agencies and the growing demand for CBD amongst health and fitness enthusiasts will bode well for the growth of the market. For instance, according to a report by the Harvard Health Institute in 2018, CBD can be extensively adopted to provide relief from health issues such as anxiety, insomnia, etc.

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The CBD oil market has experienced significant growth in recent years, driven by the increasing awareness of its potential health benefits and the legalization of cannabis in some countries. CBD is a non-psychoactive compound found in the cannabis plant that has been shown to have anti-inflammatory, analgesic, and neuroprotective properties, among others. It is used in a wide range of products, including oils, capsules, edibles, and topicals, and is believed to help with conditions such as chronic pain, anxiety, and epilepsy. The market is expected to continue to grow as more countries legalize cannabis and more research is conducted on the potential therapeutic applications of CBD.

List of Key Players Profiled in the CBD oil market Report:

Report Scope & Segmentation:

Browse Detailed Summary of Research Report with TOC:

https://www.fortunebusinessinsights.com/cannabidiol-cbd-market-103215

Market Segmentation:

On the basis of source, the market is bifurcated into marijuana and hemp. Furthermore, based on application, the market is segregated into food & beverages, pharmaceuticals, pet care, cosmetics, and others.

On the basis of application, the pharmaceuticals segment is expected to hold the largest global CBD Oil market share during the forecast period. This is owing to the constant focus on developing innovative medical products across the pharmaceutical industry worldwide. Lastly, based on region, the market is categorized into North America, Europe, Asia-Pacific, South America, and the Middle East and Africa.

What does the Report Provide?

The global CBD oil market report provides a detailed analysis of several factors such as the key drivers and restraints that will impact growth. Additionally, the report provides insights into the regional analysis that covers different regions, contributing to the growth of the market. It includes the competitive landscape that involves the leading companies and the adoption of strategies by them to introduce new products, announce partnerships, and collaborate that will further contribute to the market growth. Moreover, the research analyst has adopted several research methodologies such as PORTERs Five Point Analysis and PESTEL to obtain information about the current trends and industry developments that will drive the market growth between 2023 and 2028. Our well-revised reports help companies to receive in-depth information about the present scenario of every market so that they can adopt the necessary strategies accordingly.

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DRIVING FACTORS:

Increasing FDA Approvals for CBD Products to Promote Market Growth

The prominent players in the market are focusing on launching novel and advanced products to cater to the high demand for CBD among consumers. The increasing utilization of the product in the manufacturing of medicines and consumer products will create lucrative opportunities for the market. The rising approval grants from government agencies for various CBD products are further expected to favor the growth of the market. Additionally, the proactive focus of the manufacturers towards the incorporation of CBD in a variety of food products is expected to contribute to the global CBD Oil market growth during the forecast period.

REGIONAL INSIGHTS

North America The region stood at USD 1276.7 million in 2020 and is anticipated to hold the highest position in the market in the forthcoming years. This is attributable to the favorable government policies that enable the commercialization of cannabidiol products in countries such as the U.S. and Canada.

Europe The market in the region is anticipated to showcase exponential growth backed by the rising sales of CBD products such as vaping, smoking, and edibles in the region between 2023 and 2028.

COMPETITIVE LANDSCAPE

Major Companies Focus on Partnerships to Brighten Their Market Prospects

The global market for cannabidiol is experiencing healthy competition among key players that are focusing on partnering with other companies to expand their product portfolio and further boost sales revenues. Additionally, the other major companies are striving to maintain their presence by adopting strategies such as merger and acquisition, facility expansion, and collaboration that will bode well for the growth of the market in the forthcoming years.

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Detailed Table of Content:

TOC Continued...!

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Industry Development:

February 2020 - Colgate-Palmolive Company announced the launch of a new product in the U.S. The company reports that the product, CBD Vegan Lip Balm, will help to expand its cosmetics business in the country.

Read Related Insights:

Booming Cannabis Market to Hit USD 197.74 Billion by 2028 | An Overview of the Fastest Growing Marijuana Industry

Cannabis Beverages Market to Reach USD 19,063.58 Million by 2028 | At a CAGR 54.31%

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CBD Oil Market to Reach USD 55,791.3 Million by 2028 | With - GlobeNewswire

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Using TLC-MS for the Direct Analysis of CBD – AZoM

Posted: at 8:42 pm

The utilization of cannabis and its derivatives in nutritional supplements and medicine has increased worldwide, primarily because of the favorable regulatory status for medicinal use. As new compounds continue to arrive on the market, accessible techniques are needed to analyze product quality quickly and efficiently.

Cannabidiol (CBD) has become a popular health supplement in the UK, while multiple studies have reported analgesic anti-depressant effects. CBD is derived from the Cannabaceae genus of flowering hemp, and during the extraction process, the essential oils that create the body of the sample matrix are released.

This complex matrix presents a challenge when testing product quality. This article discusses how a QA scientist can extract CBD from the starting matrix, utilizing a hyphenated technique of CAMAG's planar chromatography technology and Microsaic's point-of-need mass spectrometer (MS) and fluidics handling platform.

Samples of CBD were acquired in three forms: 5% hemp oil droplets, 2.75% hemp oil droplets, and 10 mg capsules. These samples were mixed with methanol and injected into HPLC vials, which were then placed into the CAMAG Automatic TLC Sampler 4.

Samples were applied onto HPTLC plates (HPTLC Si RP-18 F254, 20x10) in narrow bands. Vision CATS software was employed, and plates were developed using the CAMAG Automatic Developing Chamber 2.

A developing solvent mixture of methanol, water, and acetic acid (in the respective ratio of 70:15:15) was utilized and then presented with the CAMAG TLC Visualizer 2. The CAMAG TLC 2 Interface extracted bands from the developed plate.

The extraction solvent consisted of methanol and water in a ratio of 80:20 at 0.5 ml/min. This solvent was provided by the Microsaic MiDasTM, with the extracted sample passing directly into the Microsaic 4500 MiD.

Figure 1. System configuration showing the TLC2 interface connected to the 4500 MiD. Image Credit: Microsaic Systems plc

Figure 2 presents the developed plates alongside a CBD standard for comparison. Good agreement is observed with the developed band around 0.3 rf, providing confidence that the separation has been successful.

Figure 2. Developed plate showing separated samples. Band at 0.3 rf corresponds well with reported rf value for CBD. Image Credit: Microsaic Systems plc

Mass detection is favored since it provides direct confirmation while removing the need for expensive, difficult-to-obtain reference standards. Information-rich data that contains co-eluting compounds and matrix impurities is acquired.

The developed plate was transferred to the TLC Interface 2, and the targeting laser was aligned onto the band at 0.3 rf. The sample was extracted and passed through the solvent stream via an inline filter to the MiD mass detector.

Figure 3 presents the MS data from the developed plate. A good response is observed from a full scan total ion count (TIC) over the full mass range (50-1400 m/z) in tandem with a SIM acquisition that is run concurrently (MaSScope; 315.2 m/z).

Figure 3. MaSScope data showing combination of TIC over 50-1400u mass rage and SIM scan @ 315.2. Bottom shows the mass spectrum extracted from the TIC *CBD peak (m/z 315.2; [M+H]+). Image Credit: Microsaic Systems plc

Figure 4. Mass spectrum of extracted band @ 0.3 rf CBD 315.2 m/z; [CBD+H]+. Image Credit: Microsaic Systems plc

In Figure 4, the signal in the mass spectrum, which corresponds to [CBD+H]+ is visible, which shows the sensitivity of the MiD and the flexibility to run two methods concurrently.

CAMAG planar chromatography equipment and Microsaic point-of-need technology have been employed to extract mass data from popular high-street health supplements. The accessibility of the MiD complements the CAMAG planar technology.

The intrinsic usability minimizes the time required from setup to analysis, allowing the study of developed plates to occur in line with established workflows.

As cannabis becomes more accepted in nutritional supplements and medicine, flexible methods are required to overcome these challenges. Microsaic Systems Plc and Omicron Research Ltd are committed to delivering these solutions to the point of need.

Produced from materials originally authored by Microsaic Systems Plc. The original authors wish to thank the University of Westminster and Omicron Research Ltd for access to chromatography equipment and application support.

This information has been sourced, reviewed and adapted from materials provided by Microsaic Systems plc.

For more information on this source, please visit Microsaic Systems plc.

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Using TLC-MS for the Direct Analysis of CBD - AZoM

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Cornbread Hemp Organic CBD Gummies Review – BusinessMole

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Ever since the legalization of cannabis by the2018 Farm Act, millions of people have been discovering its benefits and ways to consume it safely. Hemp products are now being recommended by wellness experts, therapists, medical doctors, and veterinarians for human and animal consumption to alleviate the symptoms of several ailments and as a health boost. As a result, the market has experienced an influx of cannabis products in multiple forms ranging from drops, pills, gummies, vapes, smokes, oils, creams, and treats for our favorite animals.

Gummies are one of the most convenient and discrete ways to consume hemp-related products. They are especially great for people with an aversion to smoking or consuming CBD oils and pills. With their exciting shapes, colors, and fruity scents, one can easily pop a gummy while their friends assume they are eating usual candies. This article thoroughly explores cornbread CBD gummies, highlighting their composition, benefits, safety, and side effects.

Cornbread Hemp is a full spectrum CBD-infused, vegan gummy bear product from a family-owned business in Kentucky. The product is made of organic CBD oils specifically sourced from Kentucky-bred hemp. The brand uses a flower-only approach, meaning that the stems, stalks, and leaves are removed in the manufacturing process to offer more potent products. The brand has an A+ customer feedback rating on most of its products, including cornbread gummies. It has never been involved in any lawsuits or received anyproduct blacklisting from the Food and Drug Administration (FDA).

Although cornbread CBD gummies are slightly pricier than other cannabis competitor brands, they are made from USDA-certified organic hemp. They have proven third-party testing and come with more potent effects, giving them good value for money. The cornbread CBD gummies are made using natural, organic apple pectin as a substitute for animal-based gelatin, so they are juicy, tender, and suitable for vegans.

The full-spectrum, flower-only formulation is packed with a fruity aroma that mutes the hemp flavor, making them a discrete choice for CBD consumption in public. The product also comes in an aesthetically pleasing glass bottle that is compact and easy to carry in a bag.

Cornbread CBD gummies are safe and non-addictive since they dont contain the psychoactive compound in marijuana THC. There are minimal chances of overdose when using these products though excess consumption will cause elongated effects, especially for newbie users. That being said, some medications and substances shouldnt be consumed together with CBD as they may severely counteract each other. Therefore, it is advisable to consult your doctor before incorporating these gummies into your health regimen.

As mentioned above, these products have undergone third-party testing for CBD and THC amounts, terpene profile, mycotoxins, microbial, foreign matter, pesticides, heavy metals, and residual solvents. The manufacturing facilities are also third-party certified and comply with theCurrent Good Manufacturing Practice (CGMP) regulations.

Cornbread gummies contain cannabidiol (CBD),which is a cannabinoid present in the cannabis plant. CBD is related to many potential health benefits because it interacts with theendocannabinoid systemin the body, a complex biological system that helps regulate and balance key bodily functions. Here are some of the health bonuses of consuming these gummies.

TheAmerican Psychology Association (APA)defines anxiety as a feeling characterized by tension, worry, and physical changes such as heightened blood pressure. Like exercise and meditation, CBD gummies are a natural way to relieve anxiety and stress. The advantage of these gummies over the other two practices is that its a quick and easy way to blow steam that doesnt require consistency, practice, or discipline to start or maintain. CBD works in collaboration with the endocannabinoid system (ECS) tobind specific brain receptorsresponsible for ease and calmness. Users have reported fast results from consuming cornbread CBD gummies, and long-term use may provide mental and emotional equilibrium.

Though the role of CBD in pain management is still under research, anecdotal evidence proves that CBD can significantly reduce chronic pain and inflammation without the dire and addictive effects caused by opioids.

Uneven sleep patterns often trigger frustration, anger, physical maladies, and unproductivity. Being a full-spectrum CBD product, cornbread CBD gummies can quickly help lull you to sleep. They are a safe, effective, natural, and healthier alternative compared to pharmaceutical sleeping pills, that are often producing undesirable medical conditions and addictions.

Anecdotal research indicates that CBD optimizes gut health by boosting mucosal defense, creating and maintaining optimal pH levels in the intestines, and controlling the stomachs natural flora. Full-spectrum CBD also reduces inflammation, thus promoting healthy digestion and food absorption and reducing nutrient waste throughout the body. Cornbread CBD gummies have also been reported to help relieve symptoms of irritable bowel syndrome, such as constipation.

Full-spectrum CBD is often associated with increased appetite, which in turn helps improve the consumers energy levels and battles lethargy. Additionally, cornbread CBD gummies have been reported to cause an energy surge in users with low energy levels who need motivation for productivity. The best thing about CBD gummies is that you can quickly pop one in the mouth without drawing attention to yourself whenever youre feeling down.

People generally tolerate CBD products well, though some may still experience side effects. The Food and Drug Administration (FDA) warns that further research is needed to determine the long-term safety of CBD use. Drowsiness, diarrhea, decreased appetite, and increased irritability are among the possible adverse effects you may encounter during the first use instances, while more serious complications connected with consistent CBD overdosing are liver damage and male fertility loss. Medication can also interact with CBD. Thus, we recommend consulting a healthcare expert before using CBD to verify that it does not interfere with any other medications or supplements you are taking. Get somecornbread hemp organic CBD gummies 1500mgfor yourself or as a gift to a loved one, and enjoy all the fantastic benefits today. Be sure to share your experience with the gummies for others to learn a thing or two about these CBD gummies.

Cornbread CBD gummies are an excellent alternative to CBD smoking, vaping, or CBD oil consumption with a dropper. They are deliciously flavored and contain only natural, organic ingredients. Thus, using a cornbread gummy is a great option to find pain or stress relief and enjoy the tangible effects of CBD in a fun way.

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Cornbread Hemp Organic CBD Gummies Review - BusinessMole

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