Daily Archives: February 7, 2022

COVID-19 infections increase risk of heart conditions up to a year later Washington University School of Medicine in St. Louis – Washington…

Posted: February 7, 2022 at 6:31 am

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Cardiovascular care essential part of post-infection care

An analysis of federal health data indicates that people who have had COVID-19 are at increased risk of developing cardiovascular complications within the first month to a year after infection, according to researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

An in-depth analysis of federal health data indicates that people who have had COVID-19 are at increased risk of developing cardiovascular complications within the first month to a year after infection. Such complications include disruptive heart rhythms, inflammation of the heart, blood clots, stroke, coronary artery disease, heart attack, heart failure or even death.

Such problems occur even among previously healthy individuals and those who have had mild COVID-19 infections, according to the study, from researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System.

The research is published Feb. 7 in Nature Medicine.

We wanted to build upon our past research on COVIDs long-term effects by taking a closer look at whats happening in peoples hearts, said senior author Ziyad Al-Aly, MD, an assistant professor of medicine at Washington University. What were seeing isnt good. COVID-19 can lead to serious cardiovascular complications and death. The heart does not regenerate or easily mend after heart damage. These are diseases that will affect people for a lifetime.

More than 380 million people globally have been infected with the virus since the pandemic started.

Consequently, COVID-19 infections have, thus far, contributed to 15 million new cases of heart disease worldwide, said Al-Aly, who treats patients within the VA St. Louis Health Care System. This is quite significant. For anyone who has had an infection, it is essential that heart health be an integral part of post-acute COVID care.

Cardiovascular disease an umbrella term that refers to various heart conditions, thrombosis and stroke is the leading cause of death in the United States and the world. The Centers for Disease Control and Prevention (CDC) estimates that one out of every four Americans dies of heart disease each year.

Additionally, heart disease comes with a hefty price tag, according to the CDC, costing the U.S. about $363 billion each year in health-care services, medications and productivity lost to death.

For people who were clearly at risk for a heart condition before becoming infected with SARS-CoV-2, the findings suggest that COVID-19 may amplify the risk, said Al-Aly, who is also director of the Clinical Epidemiology Center and chief of the Research and Education Service at the Veterans Affairs St. Louis Health Care System.

But most remarkably, people who have never had any heart problems and were considered low risk are also developing heart problems after COVID-19, he added. Our data showed an increased risk of heart damage for young people and old people; males and females; Blacks, whites and all races; people with obesity and people without; people with diabetes and those without; people with prior heart disease and no prior heart disease; people with mild COVID infections and those with more severe COVID who needed to be hospitalized for it.

The researchers analyzed de-identified medical records in a database maintained by the U.S. Department of Veterans Affairs, the nations largest integrated health-care delivery system. The researchers created a controlled dataset that included health information of 153,760 people who had tested positive for COVID-19 sometime from March 1, 2020, through Jan. 15, 2021, and who had survived the first 30 days of the disease. Very few of the people in the study were vaccinated prior to developing COVID-19, as vaccines were not yet widely available at the time of enrollment.

Statistical modeling was used to compare cardiovascular outcomes in the COVID-19 dataset with two other groups of people not infected with the virus: a control group of more than 5.6 million patients who did not have COVID-19 during the same time frame; and a control group of more than 5.8 million people who were patients from March 2018 through January 2019, well before the virus spread and the pandemic settled in.

The study does not include data involving the viruss delta and omicron variants, which began spreading rapidly in the latter half of 2021.

The COVID-19 patients in the study were mostly older, white men; however, the researchers also analyzed data that included women and adults of all ages and races.

The researchers analyzed heart health over a year-long period. Heart disease, including heart failure and death, occurred in 4% more people than those who had not been infected with COVID-19.

Some people may think 4% is a small number, but its not, given the magnitude of the pandemic, Al-Aly said. That translates to roughly 3 million people in the U.S. who have suffered cardiovascular complications due to COVID-19.

Compared with those in the control groups without any infections, people who contracted COVID-19 were 72% more likely to suffer from coronary artery disease, 63% more likely to have a heart attack and 52% more likely to experience a stroke.

Overall, those infected with the virus were 55% more likely than those without COVID-19 to suffer a major adverse cardiovascular event, which includes heart attack, stroke and death.

Our findings highlight the serious long-term cardiovascular consequences of having a COVID-19 infection and emphasize the importance of getting vaccinated against COVID-19 as a way to prevent heart damage; this also underscores the importance of increasing accessibility to the vaccines in countries with limited resources, Al-Aly said.

Governments and health systems around the world should be prepared to deal with the likely significant contribution of the COVID-19 pandemic to a rise in the burden of cardiovascular diseases, he said. Because of the chronic nature of these conditions, they will likely have long-lasting consequences for patients and health systems, and also have broad implications on economic productivity and life expectancy. Addressing the challenges posed by long-COVID will require a much needed, but so far lacking, urgent and coordinated long-term global response strategy.

Xie Y, Xu E, Bowe B, Al-Aly Z. Long-term Cardiovascular Outcomes of COVID-19. Nature Medicine. Feb. 7, 2022. DOI: https://doi.org/10.1038/s41591-022-01689-3

This research was funded by the U.S. Department of Veterans Affairs. The data that support the findings of this study are available from the U.S. Department of Veterans Affairs. VA data are made freely available to researchers behind the VA firewall with an approved VA study protocol.

Washington University School of Medicines 1,700 faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is a leader in medical research, teaching and patient care, and currently is No. 4 in research funding from the National Institutes of Health (NIH). Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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COVID-19 infections increase risk of heart conditions up to a year later Washington University School of Medicine in St. Louis - Washington...

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Can your at-home COVID-19 test go in the trash? – KRQE News 13

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by: Braley Dodson, Nexstar Media Wire

Posted: Feb 6, 2022 / 06:00 AM MST

Updated: Feb 4, 2022 / 06:25 AM MST

COLUMBIA, S.C. (WBTW) Can you throw your at-home, rapid COVID-19 test in the trash, or is it considered hazardous biological waste?

Unlike at hospitals, at-home tests can be thrown in the normal trash, the Centers for Disease Control and Prevention told the Miami Herald in January. However, some states have taken different stances.

In Delaware, schools should treat the kits as infectious waste, according to the Delaware Department of Natural Resources and Environmental Control. Schools have been directed to place used test materials in red bags, mark the bags with the biohazard symbol and tie them closed. The bags must be stored away from people and be protected from the weather, rodents and insects. The state must then remove the bags, and schools must keep a copy of the manifests for at least three years.

As for South Carolina, the Department of Health and Environmental Control said that residents should follow the instructions on the at-home tests they use.

Were not aware of any stipulations preventing an individual organization, business, school, or provider from developing their own disposal policies, but we encourage them to follow practical safety and health protocols when doing so, the agency said.

Lucira at-home COVID-19 test kits include a plastic bag for the test to be placed in and disposed of in the trash. Instructions for the QuickVue, BinaxNOW and IHealth at-home tests also say the used tests can be placed in the trash.

In California, disposal of BinaxNow test cards depends on whether or not the result was positive. For negative results, the test cards can go in the trash, while positive tests along with used swabs and other test components must be disposed of in a biohazard container according to regulated medical waste guidelines.

The CDC says tests from labs and testing sites should be treated as biohazardous waste. Rules on how to dispose of the waste vary by state, contact your local health department or COVID task force with any questions.

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The Prevalence of Depression and Related Factors During the COVID-19 Pandemic Among the General Population of the Jazan Region of Saudi Arabia -…

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Background

This study examines the rates of depression associated with the COVID-19 pandemic along with mitigation measures such as lockdown and quarantine in the population of the Jazan region in Saudi Arabia. The Kingdom of Saudi Arabia (KSA) began mitigation measures before the first case appeared on March 2, 2020, disrupting daily life in a culture that is centered on family life. We sought to assess the psychological impacts of the pandemic on this culturally unique region to see if it affected as many as other reported places in the world.

A self-reporting online questionnaire in Arabic was distributed through social media applications and a convenience sample of 942 participants 18 years of age living in the Jazan region was selected. The questionnaire included socio-demographics, economic status, chronic medical conditions, focus on and knowledge of COVID-19, and the patient health questionnaire-9 scale (PHQ-9) for depression metrics.

The data in this study were analyzed using descriptive analysis of participant characteristics, followed by Chi-square testing to compare reported depression related to each variable. Finally, to control for confounding factors, we applied multivariate logistic regression to find an adjusted odds ratio (AOR) with a 95% CI.

In the Jazan region, the rate of depression during the COVID-19 pandemic was nearly 26%. There are several significant determinants associated with higher rates of depression in descending order: those with chronic diseases were 160% higher than those without; those with a history of mental illness were 150% higher; participants who focused excessively on the pandemic 3 hours daily were 130% higher; participants who were divorced or widowed were 120% higher than singles; females were 87% higher; those under age 40 were 57% higher; students were 50% higher; those reporting low incomes were 40% higher than those with moderate incomes and 60% higher than those with high incomes.

Strategies need to be devised to protect vulnerable groups of participants from mental health effects, including depression during the COVID-19 pandemic. This will require the collaboration of various institutions, such as schools and others, to provide support for education and mental health. Future research should be aimed at determining the reasons for this higher vulnerability of some groups.

In January 2020, a novel coronavirus identified as SARS-CoV 2 spread rapidly around the world from its initial discovery in Wuhan, China, and the pandemic disease it causes, COVID-19, has continued for nearly two years [1]. The first case occurring in the Kingdom of Saudi Arabia (KSA) was reported on March 2, 2020, after the KSA had begun mitigation measures [2,3]. Mitigation measures were implemented in stages by the KSA and included requirements that radically changed the Saudi culture, which has close social daily interaction with family. Some examples of the stressful restrictions put in place were the closing of domestic travel, including to the holy cities of Mecca and Medina, as well as curfews that were imposed to prevent citizens from leaving their homes except during certain hours with a limit of only one person per household permitted to go out to obtain food and necessary supplies for the household [4,5]. The suspension of school and work, along with the enforcement of shelter at home policies, presented both a psychological and economic burden on Saudi daily life. While the physical medical care of acute COVID-19 is necessary, as one of the top 25 global illnesses of concern, depressive disorder is costly for individual wellbeing as well as society and the economy, and is a significant factor in suicide, as revealed by a review by Santomauro [6]. Symptoms of mental health disorders such as depression, anxiety, OCD, suicide, neurological, cognitive, and others have been increasing worldwide during the COVID-19 pandemic as the medical, economic, and psychological burdens continued [7-10]. These effects have proven to be long-lasting in previous pandemics such as MERS and SARS [9]. Therefore, this study is critical to assess their prevalence in the Jazan region and formulate plans for strengthening mental health along with medical conditions caused by COVID-19.

Many international studies have reported increased depression rates during the COVID-19 pandemic. Two U.S. studies comparing COVID-19-related depression to pre-covid rates on 18- to 30-year-olds observed an increase in depression following the COVID-19 shutdown of three-sevenfold, with the main factors being fewer socio-economic resources, the sudden high rate of unemployment, loneliness, and uncertainty about the course of the pandemic, while family support was very important in protecting participants from depression [7,8]. A study in Italy of the mental health of COVID-19 survivors revealed high levels of depression, possibly related to immune responses to the disease, along with some long-lasting disabilities [11]. A large systematic review and meta-analysis encompassing more than 33,000 subjects from 12 Chinese studies and one from Singapore on healthcare workers was conducted by scholars in the UK and Greece, revealing an overall depression rate of 22.8%, with the highest rates among females and nurses [12]. Investigators in Turkey examined depression, anxiety, and health anxiety during the COVID-19 period and found the rate of depression to be slightly more than 23%, with the strongest correlating factor being the female gender [13]. Chinese scholars examined depression and anxiety using an online questionnaire distributed nationally to adults who did not have a previous history of mental health conditions and reported a 20.4% rate of depression and/or anxiety or both, with a relationship to time spent focusing on COVID-19 news [14].

There are several Saudi studies of depression rates in the KSA related to COVID-19. As with international studies, multiple authors found similar factors contributing to symptoms of depression, such as being female, being younger than 30 years old, spending a lot of time focused on COVID-19 news, and having someone with COVID-19 within their circle of acquaintances [15-18]. Studies conducted on healthcare workers in the KSA and Egypt and university students in the KSA revealed depression rates of 69% and nearly 49%, respectively, with additional related factors of lack of emotional support and the presence of pre-existing medical or mental conditions [15,18]. Other studies cited other factors that are associated with increased rates of depression, such as being non-Saudi, unemployment, low income, being over 50 years old, being divorced, being retired, being single, and smoking [19,20]. Among the studies of the general population, depression rates were observed to range from 9.4% to 65%, but none of these studies concentrated on a single region, such as the Jazan region [16,17,19].

The aim of this study was to examine COVID-19-related depression rates and associated factors for the Jazan region of the KSA in order to provide background for planning purposes. Any pandemic will have an impact on the economic conditionsand psychological health as well as the physical health of a population. Therefore, it is prudent to assess the experience of the COVID-19 pandemic to provide awareness of the importance that mental health plays in the resilience of society. This study provides guidance to both address the current status of psychological health in the population of the Jazan region as well as prepare for future traumatic events with the goal of prevention of the worst effects.

An electronic questionnaire was created in Arabic using the Google Survey tool (Google LLC, Mountain View, California, USA) to conduct a cross-sectionally designed study to assess depression levels related to the COVID-19 pandemic and quarantine in the Jazan region of the KSA. The survey was then distributed via the social media platforms Twitter and WhatsApp and users were invited to participate if they met the inclusion criteria during the four-day period of May 28, 2020 through May 31, 2020. A convenience sample was selected from the eligible respondents. This self-reporting survey included sections on demographics, socioeconomic characteristics, pre-existing medical and mental health conditions, and the patient health questionnaire-9 scale (PHQ-9), an Arabic version whose validity has been established by Cronbachs = 0.857, with questions about depressive symptoms [21]. An online survey was necessary during the period of the COVID-19 pandemic lockdown since it was not possible to conduct in-person surveys. This method is in widespread use by researchers around the world [8,17-20]. The survey, titled "Psychological Impact(s) in Southern Saudi Arabia" was accessible via a link that explained the following inclusion criteria: participants had to be 18 years of age, residents of the Jazan region of the KSA, able to read and understand Arabic, and physically, mentally, and emotionally able to complete the form. Exclusion criteria included being <18 years of age, not being a resident of the Jazan region, being a non-Arabic speaker, and being mentally, emotionally, or physically unable to answer questions. The survey cover page explained the purpose of the questionnaire and the consent.

Data were collected for 942 participants who voluntarily filled out an electronic questionnaire distributed on May 28, 2020 through May 31,2020 on either Twitter or WhatsApp. Participant inclusion criteria were 18 years old, currently living in the Jazan region of the KSA, Arabic speakers, physically capable of filling out the form, and mentally and emotionally able to fill out the form. Exclusion criteria were <18 years old, not currently living in the Jazan region of the KSA, non-Arabic speakers, and not physically, mentally, or emotionally able to fill out the form. Informed consent was included on the questionnaire, and the privacy of the participants was maintained throughout the data collection. The questionnaire was composed of four sections of questions on socioeconomics, demographics, focus on and knowledge of COVID-19, and mental health symptoms.

The Epi InfoTM7 (Centers for Disease Control and Prevention, Atlanta, Georgia, USA) was employed to determine a statistically sufficient sample size. The minimum required sample size calculated through this method was 511 in order to provide no more than a 5% margin of error with a 99% confidence interval (CI). Therefore, our sample size of 942 increased the power of our statistical model [22]. We anticipated that nearly doubling the sample size would avoid sampling bias with the use of an online questionnaire [22].

Data were collected for 942 participants who voluntarily filled out an electronic questionnaire distributed on May 28, 2020 through May 31,2020 on either Twitter or WhatsApp. Participant inclusion criteria were 18 years old, currently living in the Jazan region of the KSA, Arabic speakers, physically capable of filling out the form, and mentally and emotionally able to fill out the form. Exclusion criteria were <18 years old, not currently living in the Jazan region of the KSA, non-Arabic speakers, and not physically, mentally, or emotionally able to fill out the form. Informed consent was included on the questionnaire, and the privacy of the participants was maintained throughout the data collection. The questionnaire was composed of four sections of questions on socioeconomics, demographics, focus on and knowledge of COVID-19, and mental health symptoms.

The Epi InfoTM7 (Centers for Disease Control and Prevention, Atlanta, Georgia, USA) was employed to determine a statistically sufficient sample size. The minimum required sample size calculated through this method was 511 in order to provide no more than a 5% margin of error with a 99% confidence interval (CI). Therefore, our sample size of 942 increased the power of our statistical model [22]. We anticipated that nearly doubling the sample size would avoid sampling bias with the use of an online questionnaire [23].

The Statistical Package for Stata 2014 version (StataCorp LLC, Texas, USA) was used to analyze all the data, with a p-value of 0.05 considered statistically significant. The data in this study were analyzed in a stepwise process. The first step was to perform a descriptive analysis of participant characteristics. The second step was to use Chi-square testing to compare reported depression related to each variable. In the third step to control for confounding factors, we applied multivariate logistic regression to find an adjusted odds ratio (AOR) with a 95% CI.

Table 1 presents a description of the characteristics of the participants grouped into those reporting and those not reporting depressive symptoms (DS). The following characteristics showed statistically significant differences: 86% of the overall sample was aged <40, and those under 40 accounted for more than double the number reporting DS. Females made up three-fourths of the total sample, and they accounted for one-and-a-half times as many among those reporting DS. Married participants represented only 40% of the sample and also had only one-fifth of those with reported DS, while divorced or widowed participants had double the reported DS. Of the total participants, less than one-fifth had chronic diseases, but they accounted for 60% more of the reported DS. Only 3% of the total sample reported previous mental illnesses, but they accounted for almost double the number of those reporting DS. Students reported one and a half times the rate of DS as those working and unemployed or retired, representing approximately 20% higher reported DS. In regards to the standard of living (SOL), those who reported a limited SOL and those with a high SOL each represented approximately 20% of the total sample. However, those with a limited SOL reported more than double the DS as those with a high SOL, while those reporting a moderate SOL fell between the two extremes. While 98% of participants reside with others, those participants reported five times the rate of DS. The final characteristic that showed statistical significance was time spent focusing on COVID-19, in which increasing time is directly related to reported DS, such that those spending 3 hours per day reported DS at a rate nearly double that of those who focused on it <1 hour per day. All other characteristics did not show statistically significant differences among those reporting DS. These include nationality, a diagnosis of COVID-19, BMI, smoking status, education level, working in the healthcare field, financial responsibility, and knowledge of COVID-19.

Table 2 shows the multi-logistic regression with several statistically significant factors that were associated with reported depression during the COVID-19 pandemic as follows: females 87% more compared to males, aged less than 40 are 57% more than participants aged more than 40, being divorced or widowed is 120% more than being single, participants with chronic diseases including chest diseases (160%), participants with previous mental illnesses are 150% more, being a student is 50% more than being a worker or retired, low income is 40% more and 60% more than moderate and high income, respectively, and time spent focusing on the COVID-19 is less than one hour daily.

This study assessed the association of depression rates with the 2020 COVID-19 pandemic and the risk factors in the Jazan Region, KSA. Depression is one of the top 25 illnesses of global concern and is associated with increases in other diseases and suicide, making it crucial to address for policymakers [6]. Our study observed that the depression rate of participants was nearly 26%, which is in the mid-range of a previous systematic review of the association of the pandemic with depression rates, which reported rates as low as 14.6% to as high as 32.7% in countries as diverse as Denmark, the U.S., China, Nepal, Spain, Italy, and Iran [24]. Several other international studies reported rates of 14-18% in China, 18.7% in Spain, 32.7% in Italy, 23.6% in Turkey, and 25.4% in Denmark [11,13,25-29].

Our data revealed a statistically significant relationship between some factors and the increasing frequency of depressive symptoms among the participants. Compared to participants with no pre-existing conditions, those with chronic diseases had a 160% higher incidence of depressive symptoms. This finding is consistent with several international studies of the association of the COVID-19 pandemic with depression, reporting that patients with chronic diseases or multiple comorbidities are at an increased risk of psychological symptoms, including depression, possibly due to awareness of the severity of COVID-19 for this group [30-33]. Compared to those with no history of mental illness, participants with a history of diagnosed mental illness had a 150% higher incidence. This finding is also consistent with international studies that do have some mixed findings, as reported by Bell et al., in which one case-controlled study in the Netherlands found that although a history of mental illness predisposes individuals to a higher risk of depression, the rates did not increase in response to the pandemic [34,35]. However, the preponderance of studies reported results consistent with this study or higher rates of depression among those with a history of mental illness [36-40]. Increasing focus on the pandemic increased depression, whereby compared to those who focused on it less than one hour daily, those who focused on it three hours or more daily had a 130% higher incidence of depressive symptoms. This finding aligns with other international studies that have examined the association of consuming a lot of media coverage of the pandemic with the participants' mental state [41,42].

With media coverage now expanded to innumerable sources, there is a constant flow of information, much of which may be exaggerated or misleading, but nevertheless will have an impact on the mental health of those who consume large quantities of it [43-45]. While excessive focus on the pandemic is correlated with negative mental health effects, social media platforms represent a dual-edged sword. Chinese studies have shown that 80% of the population utilizes social media for news and in India, more than 90% obtain their medical information via the internet [9]. On one hand, the barrage of misinformation, conspiracy theories, and negative personal posts leads to increased frustration when trying to discriminate between sources [46]. On the other hand, the connectivity provided with the outside world during enforced quarantine can lessen the sense of isolation [46]. Additionally, during this pandemic, legitimate health authorities placed accurate information on these sites and users also created their own information networks to inform their contacts of resources, such as in India when there were shortages of oxygen and ventilators, while communication was made possible between family members and hospitalized COVID patients [46]. Finally, many studies, such as this one, have relied on social media platforms to conduct primary research.

Compared to single participants, those who were either divorced or widowed had a 120% higher incidence. Compared to males, female participants had an 87% higher incidence, while compared to those over 40, those under 40 had a 57% higher incidence. Other studies have also shown that females have demonstrated higher rates of depressive symptoms in response to COVID-19 [13,47-49], but the reasons for this are still speculative, such as the increased burden of care borne by females, hormonal influences, and brain reactivity that results in higher fear responses [50-52]. Many other studies have similarly documented that younger people have had higher rates of depressive symptoms, possibly due to their higher exposure to social media with its attendant constant coverage of the pandemic, and this group may be more impacted by lockdowns and social isolation [48,53-55]. Economic factors also played a role in that, compared to participants who were either working or retired, students had a 50% higher incidence of depressive symptoms, which is consistent with many other studies. A study from the Netherlands measured mood homeostasis before and during a stringent lockdown on college students and reported a decrease in the mood-elevating activities after the lockdown compared to before [56]. Multiple studies have confirmed the association of increased depressive symptoms and the COVID-19 pandemic among students for reasons of isolation, lack of social support, worry about missing school, and others [53,57-60]. Finally, our finding that income levels represent a risk since, compared to participants with a moderate or high income, those with a low income had a 40% and 60% higher incidence, respectively, is supported by other international studies [54,55].

The KSA had prepared for a pandemic after the MERS outbreak of 2012 and thus handled the COVID-19 pandemic in 2020 relatively well. However, the mental health aspects were not anticipated. In view of the increase in depressive symptoms accompanying the COVID-19 pandemic, it is wise to take this opportunity to plan mitigation measures both for the current as well as any future pandemics. High-risk groups included those with comorbidities, a history of mental illness, a habit of focusing on the pandemic, females, young people, students, and low-income participants. Strategies to address the needs of these groups should be sought from multiple sectors of society, especially institutions such as schools. The medical establishment should address mental health issues so that they are part of risk management along with the medical consequences of pandemics. Ozamiz-Etxebarria has suggested that academic support be enhanced to help alleviate some of the psychological effects on students and the young [31]. The provision of a central source of accurate information may alleviate some of the fear and depression that are fueled by sensationalist news and misinformation from the public media. Further research is needed to find the source of depressive symptoms in the higher risk groups and to measure the mental health impacts of the pandemic over the long term in the Jazan Region.

Although this first study of depression associated with the COVID-19 pandemic is very rigorous, we must mention its limitations. First, this study should not be generalized to the entire population of the KSA as it is specific to the Jazan region, which may differ from the population as a whole. Second, the necessity of conducting this original research through an online survey automatically excludes those who do not participate in the applications through which it was distributed. Third, the use of a convenience sample may have inadvertently led to sampling bias, although we followed standard protocol to avoid such bias. Finally, the survey instrument cannot assign cause and effect to this cross-sectional study.

In the Jazan region, the rate of depression during the COVID-19 pandemic was nearly 26%. In addition, there are several significant determinants associated with higher rates of depression, in descending order: history of chronic diseases, history of mental illness, excessive focus on the pandemic, being divorced or widowed, female gender, being under age 40, being a student, having a low income. This study clearly demonstrates a relationship between the COVID-19 pandemic and depression in the Jazan region. We suggest prioritizing mental health prior to the next pandemic, encouraging the medical establishment to plan to integrate mental health into the care provided to vulnerable populations, and a public information system to provide accurate information in the event of such a health crisis. We recommend further research into more detailed causal effects of depression and also longer-term studies to capture the changing mental health landscape. Additional suggestions are noted in the discussion in this paper.

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Difference Between Quantum Physics and Quantum Mechanics …

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August 26, 2011 Posted by Madhu

The key difference between quantum physics and quantum mechanics is that quantum physics is a branch of science that focuses on quantum mechanics whereas quantum mechanics is the set of principals used to explain the behaviour of matter and energy.

People use the terms quantum physics and quantum mechanics with different meanings. Although we sometimes use these terms to describe the same thing, there is a difference between quantum physics and quantum mechanics. We can identify quantum physics as a branch of science that study theories like quantum mechanics and quantum field theory. In other words, mechanics is a set of theories we study in the branch of science known as physics.

1. Overview and Key Difference2. What isQuantum Physics3. What isQuantum Mechanics4. Side by Side Comparison Quantum Physics vs Quantum Mechanics in Tabular Form5. Summary

Quantum physics is a branch of science that focuses on systems explained by theories such as quantum mechanics and quantum field theory. Scientists and researchers focus on this area in order to use this knowledge to understand the behaviour of particles at the subatomic level. However, sometimes we use the terms quantum physics and quantum mechanics interchangeably.

Quantum mechanics is the set of principle that explains the behaviour of matter at atomic (or subatomic) scale. The word quantum itself describes a fundamental concept of quantum mechanics the quantized or discrete nature of matter and energy.

Quantum mechanics was born when Max Plank introduced the concept of quantized energy (E =nhf) to explain the blackbody thermal radiation. Then, Einstein came up with the concept of photon to explain the particle nature of light. It led to a theory known as wave-particle duality, which describes the possession of both wave and particle qualities by matter and energy. Louis de Broglie introduced this concept.

Fundamental concepts of quantum mechanics also include Bohr models to describe atomic structure by Niels Bohr, Schrdinger equation (widely used equation to calculate quantum waves) byErwin Schrdinger, uncertainty principle (which explains the probabilistic nature of matter and energy) by Werner Heisenberg, and Pauli Exclusion Principle by Wolfgang Pauli. The explanation known as Copenhagen interpretationand the phenomenon known as quantum entanglement also belong to the quantum mechanics.

Quantum physics is a major branch of science while quantum mechanics is a branch of quantum physics. So, the key difference between quantum physics and quantum mechanics is that quantum physics is a branch of science that focuses on quantum mechanics whereas quantum mechanics is the set of principals that explain the behaviour of matter and energy.

Furthermore, quantum physics can predict and describe the properties of a physical system while quantum mechanics can describe properties of molecules, atoms and subatomic particles regarding the interactions between them and with electromagnetic radiation. Therefore, this is the difference between quantum physics and quantum mechanics in terms of their usage.

Although we use the terms quantum physics and quantum mechanics interchangeably, they are different from each other. The key difference between quantum physics and quantum mechanics is that quantum physics is a branch of science which focuses on quantum mechanics whereas quantum mechanics is the set of principals that explains the behaviour of matter and energy.

1. Squires, Gordon Leslie. Quantum Mechanics. Encyclopdia Britannica, Encyclopdia Britannica, Inc., 3 Aug. 2018, Available here.

1. 3871213 (CC0) via Pixabay

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Difference Between Quantum Physics and Quantum Mechanics ...

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Quantum Time Exactly What Is Time?

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Max Planck is sometimes considered the father of quantum theory

In the first half of the 20th Century, a whole new theory of physics was developed, which has superseded everything we know about classical physics, and even the Theory of Relativity, which is still a classical model at heart. Quantum theory or quantum mechanics is now recognized as the most correct and accurate model of the universe, particularly at sub-atomic scales, although for large objects classical Newtonian and relativistic physics work adequately.

If the concepts and predictions of relativity (see the section on Relativistic Time) are often considered difficult and counter-intuitive, many of the basic tenets and implications of quantum mechanics may appear absolutely bizarre and inconceivable, but they have been repeatedly proven to be true, and it is now one of the most rigorously tested physical models of all time.

One of the implications of quantum mechanics is that certain aspects and properties of the universe are quantized, i.e. they are composed of discrete, indivisible packets or quanta. For instance, the electrons orbiting an atom are found in specific fixed orbits and do not slide nearer or further from the nucleus as their energy levels change, but jump from one discrete quantum state to another. Even light, which we know to be a type of electromagnetic radiation which moves in waves, is also composed of quanta or particles of light called photons, so that light has aspects of both waves AND particles, and sometimes it behaves like a wave and sometimes it behaved like a particle (wave-particle duality).

An obvious question, then, would be: is time divided up into discrete quanta? According to quantum mechanics, the answer appears to be no, and time appears to be in fact smooth and continuous (contrary to common belief, not everything in quantum theory is quantized). Tests have been carried outusing sophisticated timing equipment and pulsating laser beams to observe chemical changes taking place at very small fractions of a second (down to a femtosecond, or 1015 seconds) and at that level timecertainly appears to be smooth and continuous. However,if time actually is quantized, it is likely to be at the level of Planck time (about 10-43 seconds), the smallest possible length of time according to theoretical physics, and probably forever beyond our practical measurement abilities.

It should be noted that our current knowledge of physics remains incomplete, and, according to some theories that look to combine quantum mechanics and gravity into a single theory of everything (often referred to as quantum gravity see below), there is a possibility that time could in fact be quantized. A hypothetical chronon unit for a proposed discrete quantum of time has been proposed, although it is not clear just how long a chronon should be.

One of the main tenets of quantum theory is that the position of a particle is described by a wave function, which provides the probabilities of finding the particle at any number of different places, or superpositions. It is only when the particle is observed, and the wave function collapses, that the particle is definitively located in one particular place or another. So, in quantum theory, unlike in classical physics, there is a difference between what we see and what actually exists. In fact, the very act of observation affects the observed particle.

Another aspect of quantum theory is the uncertainty principle, which says that the values of certain pairs of variables (such as a particles location and its speed or momentum) cannot BOTH be known exactly, so that the more precisely one variable is known, the less precisely the other can be known. This is reflected in the probabilistic approach of quantum mechanics, something very foreign to the deterministic and certain nature of classical physics.

This view of quantum mechanics (developed by two of the originators of quantum theory, Niels Bohr and Werner Heisenberg), is sometimes referred to the Copenhagen interpretation of quantum mechanics. Because the collapse of the wave function cannot be undone, and because all the information associated with the initial possible positions of the particle contained in the wave function is essentially lost as soon as it is observed and collapsed, the process is considered to be time-irreversible, which has implications for the so-called arrow of time, the one way direction of time that we observe in daily life (see the section on The Arrow of Time).

Some quantum physicists (e.g. Don Page and William Wootters) have developed a theory that time is actually an emergent phenomenon resulting from a strange quantum concept known as entanglement, in which different quantum particles effectively share an existence, even though physically separated, so that the quantum state of each particle can only be described relative to the other entangled particles. The theory even claims to have experimental proof recently, from experiments by Ekaterina Moreva which show that observers do not detect any change in quantum particles (i.e. time foes not emerge) until becoming entangled with another particle.

The Copenhagen interpretation of quantum mechanics, mentioned above, is not however the only way of looking at it. Frustrated by the apparent failure of the Copenhagen interpretation to deal with questions like what counts as an observation, and what is the dividing line between the microscopic quantum world and the macroscopic classical world, other alternative viewpoints have been suggested. One of the leading alternatives is the many worlds interpretation, first put forward by Hugh Everett III back in the late 1950s.

According to the many worlds view, there is no difference between a particle or system before and after it has been observed, and no separate way of evolving. In fact, the observer himself is a quantum system, which interacts with other quantum systems, with different possible versions seeing the particle or object in different positions, for example. These different versions exist concurrently in different alternative or parallel universes. Thus, each time quantum systems interact with each other, the wave function does not collapse but actually splits into alternative versions of reality, all of which are equally real.

This view has the advantage of conserving all the information from wave functions so that each individual universe is completely deterministic, and the wave function can be evolved forwards and backwards. Under this interpretation, quantum mechanics is therefore NOT the underlying reason for the arrow of time.

Quantum gravity, or the quantum theory of gravity, refers to various attempts to combine our two best models of the physics of the universe, quantum mechanics and general relativity, into a workable whole. It looks to describe the force of gravity according to the principles of quantum mechanics, and represents an essential step towards the holy grail of physics, a so-called theory of everything. Quantum theory and relativity, while coexisting happily in most respects, appear to be fundamentally incompatible at unapproachable events like the singularities in black holes and the Big Bang itself, and it is believed by many that some synthesis of the two theories is essential in acquiring a real handle on the fundamental nature of time itself.

Many different approaches to the riddle of quantum gravity have been proposed over the years, ranging from string theory and superstring theory to M-theory and brane theory, supergravity, loop quantum gravity, etc. This is the cutting edge of modern physics, and if a breakthrough were to occur it would likely be as revolutionary and paradigm-breaking as relativity was in 1905, and could completely change our understanding of time.

Any theory of quantum gravity has to deal with the inherent incompatibilities of quantum theory and relativity, not the least of which is the so-called problem of time that time is taken to have a different meaning in quantum mechanics and general relativity. This is perhaps best exemplified by the Wheeler-DeWitt equation, devised by John Wheeler and Bruce DeWitt back in the 1970s. Their attempt to unify relativity and quantum mechanics resulted in time essentially disappearing completely from their equations, suggesting that time does not exist at all and that, at its most fundamental level, the universe is timeless. In response to the Wheeler-DeWitt equation, some have concluded that time is a kind of fictitious variable in physics, and that we are perhaps confusing the measurement of different physical variables with the actual existence of something we call time.

While looking to connect quantum field theory with statistical mechanics, theoretical physicist Stephen Hawking introduced a concept he called imaginary time. Although rather difficult to visualize, imaginary time is not imaginary in the sense of being unreal or made-up. Rather, it bears a similar relationship to normal physical time as the imaginary number scale does to the real numbers in the complex plane, and can perhaps best be portrayed as an axis running perpendicular to that of regular time. It provides a way of looking at the time dimension as if it were a dimension of space, so that it is possible to move forwards and backwards along it, justas one can move right and left or up and down in space.

Despite its rather abstract and counter-intuitive nature, the usefulness of imaginary time arises in its ability to help mathematically to smooth out gravitational singularities in models of the universe. Normally, singularities (like those at the centre of black holes, or the Big Bang itself) pose a problem for physicists, because they are areas where the known physical laws just do not apply. When visualized in imaginary time, however, the singularity is removed and the Big Bang functions like any other point in space-time.

Exactly what such a concept might represent in the real world, though,is unknown, and currently it remainslittle more than a potentially useful theoretical construct.

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Einstein Finally Warms Up to Quantum Mechanics? The Solution Is Shockingly Intuitive – SciTechDaily

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Einstein was no stranger to mathematical challenges. He struggled to define energy in a way that acknowledged both the law of energy conservation and covariance, which is general relativitys fundamental feature where physical laws are the same for all observers.

A research team at Kyoto Universitys Yukawa Institute for Theoretical Physics has now proposed a novel approach to this longstanding problem by defining energy to incorporate the concept of entropy. Although a great deal of effort has gone into reconciling the elegance of general relativity with quantum mechanics, team member Shuichi Yokoyama says, The solution is shockingly intuitive.

Einsteins field equations describe how matter and energy shape spacetime and how in turn the structure of spacetime moves matter and energy. Solving this set of equations, however, is notoriously difficult, such as with pinning down the behavior of a charge associated with an energy-momentum tensor, the troublesome factor that describes mass and energy.

The research team has observed that the conservation of charge resembles entropy, which can be described as a measure of the number of different ways of arranging parts of a system.

And theres the rub: conserved entropy defies this standard definition.

The existence of this conserved quantity contradicts a principle in basic physics known as Noethers theorem, in which conservation of any quantity generally arises because of some kind of symmetry in a system.

Surprised that other researchers have not already applied this new definition of the energy-momentum tensor, another team member, Shinya Aoki, adds that he is also intrigued that in general curved spacetime, a conserved quantity can be defined even without symmetry.

In fact, the team has also applied this novel approach to observe a variety of cosmic phenomena, such as the expansion of the universe and black holes. While the calculations correspond well with the currently accepted behavior of entropy for a Schwarzschild black hole, the equations show that entropy density is concentrated at the singularity in the center of the black hole, a region where spacetime becomes poorly defined.

The authors hope that their research will spur deeper discussion among many scientists not only in gravity theory but also in basic physics.

Reference: Charge conservation, entropy current and gravitation by Sinya Aoki, Tetsuya Onogi and Shuichi Yokoyama, 2 November 2021, International Journal of Modern Physics A.DOI: 10.1142/S0217751X21502018

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How the Physics of Resonance Shapes Reality – WIRED

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Almost anytime physicists announce that theyve discovered a new particle, whether its the Higgs boson or the recently bagged double-charm tetraquark, what theyve actually spotted is a small bump rising from an otherwise smooth curve on a plot. Such a bump is the unmistakable signature of resonance, one of the most ubiquitous phenomena in nature.

Resonance underlies aspects of the world as diverse as music, nuclear fusion in dying stars, and even the very existence of subatomic particles. Heres how the same effect manifests in such varied settings, from everyday life down to the smallest scales.

In its simplest form, resonance occurs when an object experiences an oscillating force thats close to one of its natural frequencies, at which it easily oscillates. That objects have natural frequencies is one of the bedrock properties of both math and the universe, said Matt Strassler, a particle physicist affiliated with Harvard University who is writing a book about the Higgs boson. A playground swing is one familiar example: Knock something like that around, and it will always pick out its resonant frequency automatically, Strassler said. Or flick a wineglass and the rim will vibrate a few hundred times per second, producing a characteristic tone as the vibrations transfer to the surrounding air.

A systems natural frequencies depend on its intrinsic properties: For a flute, for instance, they are the frequencies of sound waves that exactly fit inside its cylindrical geometry.

The Swiss mathematician Leonhard Euler solved the equation describing a system continuously driven near its resonant frequency in 1739. He found that the system exhibited various and wonderful motions, as he put it in a letter to fellow mathematician Johann Bernoulli, and that, when the system is driven precisely at the resonant frequency, the amplitude of the motion increases continually and finally grows out to infinity.

Driving a system too hard at the right frequency can have dramatic effects: A trained singer, for instance, can shatter a glass with a sustained note at its resonant frequency. A bridge resonating with the footsteps of marching soldiers can collapse. But more often, energy loss, which Eulers analysis neglected, prevents the motion of a physical system from growing unchecked. If the singer sings the note quietly, vibrations in the glass will grow at first, but larger vibrations cause more energy to radiate outward as sound waves than before, so eventually a balance will be achieved that results in vibrations with constant amplitude.

Now suppose the singer starts with a low note and continuously glides up in pitch. As the singer sweeps past the frequency at which the wineglass resonates, the sound momentarily grows much louder. This enhancement arises because the sound waves arrive at the glass in sync with vibrations that are already present, just as pushing on a swing at the right time can amplify its initial motion. A plot of the sound amplitude as a function of frequency would trace out a curve with a pronounced bump around the resonant frequency, one thats strikingly similar to the bumps heralding particle discoveries. In both cases, the bumps width reflects how lossy the system is, indicating, for instance, how long a glass rings after it is struck once, or how long a particle exists before it decays.

But why do particles behave like humming wineglasses? At the turn of the 20th century, resonance was understood to be a property of vibrating and oscillating systems. Particles, which travel in straight lines and scatter like billiard balls, seemed far removed from this branch of physics.

The development of quantum mechanics showed otherwise. Experiments indicated that light, which had been thought of as an electromagnetic wave, sometimes behaves like a particle: a photon, which possesses an amount of energy proportional to the frequency of the associated wave. Meanwhile, matter particles like electrons sometimes exhibit wavelike behavior with the same relation between frequency and energy.

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Opinion/Ng: As we observe Black History Month, what RI’s past sins can teach us – The Providence Journal

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It was the last class of my last semester of my last year in college.The course was the theory of quantum physics and, although it was more than four decades ago, I never have forgotten my bespectacled philosophyprofessor with his thick, black, curly hair standing at the front of the classroom, back when we still used chalk and leisure suits were in style.

He was my kind of teacher, part poet, part showman, and all fun. He had the right skill set to teach non-science majors like me about the importance of physics, not the calculations and numbers, but the theorem that the world can be seen in different dimensions.

Opinion/Ng: Decorated Green Beret reports for duty as Journal's new veterans columnist

Before you graduate, he said to us, I have one final assignment for you.

Some people believe that the solutions to our problems are in the future, yet to be discovered, I recall him saying. Others believe those solutions are rooted in our past, in our history. What do you think is the answer? And with that …, he said, bowing and lowering his outstretched arms as if he were taking acurtain call, …I will leave you with thatfinal riddle.

And off into the world I went.

Of course, the purpose of the riddle was not to find an answer but to examine how we think and how we look atchallenges in life, and to understandthat our conclusion, like those ink-blotted Rorschach tests, says more about who we really are than what we actually see right there in front of us.

So, my answer is history.

Opinion/Ng: For a RI doctor and me, it's only three degrees of separation instead of six

When I first moved to Providence, I could not help but notice that many of the restaurants and shops in downtown taped signs in the windows.Black Lives Matter. Justice for George Floyd. Justice for Breonna Taylor. The call and the passion for racial justice were there in open view, and I learned that my new town did not shy away from the issue but instead embraced it.

To mark Black History Month,I searchedour archives at The Providence Journal on issues related to Rhode Islands history on race, its sins and atonement.

In 2006, The Journal published a 15-part series called Rhode Island and The Slave Trade that detailed how some of our now most-heralded communities Newport, Bristol and Narragansett were bastions of forced labor of human beings brought here in chains. It includes stories about how some of the states forefathers brutalizedliving souls who, to the owners, were no more than possession thathappened to be made of flesh and blood.

But it also outlines how evenin the 1770s a debate was raging in Rhode Island on the morality of slavery, if not its legality.For even in 1787, when Rhode Island outlawed slave trading, the trafficking did not stop.Nearly half of the states slave voyages occurred after trading was banned, with much of the trade relocating from Newport to Bristol.

More: An executive editor's best memories of his rookie year in Rhode Island

The stain of slavery cannot be wiped clean, even if we fill a library full of books about that grim chapter.But remembering that history is a first step.

Our reporter Amy Russo wrote in November 2021 how Brown University released an updated editionof a study examining its ties to slavery more than a decade after it had alreadyacknowledged its complicity in slavery and conceded that the university's prosperity was tainted.

The legacy of slavery is thatit is asin that keeps on taking. But it also affords us the opportunity for redemption.

Amy reported that same monthhow the Providence Preservation Society conceded that in the late 1950s and early 1960s, centuries after the first slave ships set sail from Rhode Island, it had played a role in the displacement ofresidents, mostly African Americans and people of Cape Verdean descent, from the area once known as Lippitt Hill, in the name of historic preservation.

Opinion/Ng: How a serious bike crash led to my favorite story of 2021 from Executive Editor David Ng

For the article, Amy tracked down those from a generation displaced by gentrification. "The entire East Side was decimated," Deborah Johnson told Amy, remembering how her world was upended when she was only 11. "It felt to me like it happened overnight.Swoop! Gone."

But in the hopes of righting a wrong, the Preservation Society said it would now diversify its board and advisory committees and assist people of color. It cannot undo the past, but perhaps it can help chart a new future.It's one step, with the promise of many more to come.

Our State House reporter Patrick Anderson has been tracking the two-year effortto implement voters' decision to shortenthe state's namefrom"State of Rhode Island and Providence Plantations" to "Rhode Island." But printing up new stationeryis one thing; scrubbing words that are literally carved into stone on a building is another.The analogy cannot be ignored. Some sins are not easily erased.

Still, it is one step.

Opinion/Ng: A memorable lesson on how to treat those in need

Voices more eloquent than mine have valued the lessons of history.

"Those who do not remember the past are condemned to repeat it." George Santayana, philosopher.

"Difficulty is the excuse history never accepts." Edward R. Murrow

"We are not makers of history. We are made by history." Dr. Martin Luther King Jr.

So yes, my answeris history.

David Ng is executive editor of The Providence Journal. Email him atdng@providencejournal.com.

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Answer the Call: Stream Apple TV’s New Sci-Fi Mystery | The Wooster Voice – The Wooster Voice

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Jonathan Logan

Editor in Chief

Audio drama and motion picture tell a story in two very different forms. The radio adaptation of H.G. Wells War of the Worlds is an audio drama that most people are familiar with, after its airing on CBS Radio in 1938 convinced many listeners Earth was under alien attack. Audio dramas counterpart, silent films, make do without sound, just as compelling audio drama makes do without visual information.

Both mediums take advantage of sensory deprivation by going without either audio or visual stimuli. Apple TVs Calls, directed by Fede Alvarez, merges both audio and visual drama by withholding exact visual information and restricting the viewer to hear only phone calls between two people. The nine episode series tells the story of an apocalyptic event through a series of phone calls that cross timelines and make viewers scream at their screens as a star-studded cast, including Rosario Dawson and Pedro Pascal, acts out their roles to a tee. The phone calls are played over visceral, synth-style visuals that allow the mind to build its own world.

The show starts out at the end. Time advances at a rate of one second per second for all of us together, but Calls wants us to ask questions about our own individual timelines. What if there is always a beginning and an end to our stories that could be accessed not via any direct experience, but by phone calls? Without direct experiences involving their five senses (or however many humans might have) the characters go through the same sensory deprivation we, the viewers, go through. A simple phone call from one character to another turns into a mind-voyage as an unexplained anomaly connects people to other timelines, to their past or future selves and to loved ones. They can only use words to talk to the confused person on another timeline as they both try to make sense of an end-of-times event that they dont realize they are directly involved in!

Most science fiction stories today treat quantum mechanics and parallel universes like the Staples button (that was easy). When stories need to explain a phenomenon science cant explain, they throw quantum foam onto an already sloshy ocean in the hopes that well never see deeper than the surface. Calls does not do this. Instead of slapping the quantum Staples button and using parallel universe jargon, it asks us to believe in many worlds, in other possibilities. Instead of trying to prove that many worlds exist, the show, via character Dr. Wheating, gives viewers a simple thought experiment: imagine that a persons entire life exists on another train (world) that left the station (being born) just before your train (your world) left the station. Of course, the same is true for past versions of their life.

Calls forces you to tap into a resonant sense you never knew you had in an attempt to make up for the lack of directly experiencing other train rides. The characters inability to directly access these other worlds can be explained by not being able to jump from one train to another. Trains can also accelerate, meaning our timelines get out of phase with other timelines. In some episodes, a character will call a loved one or a friend three or four times in the span of just 20 minutes for them, but because worlds can be out of phase, they end up talking to their loved ones or friends for what is to them 20 years or more.

To compensate for the anomaly that is connecting people to their past and future timelines, the Universe kills whomever they talk to. By the last episode, so many people have accessed their other lives via phone calls that the Universe (or Many Worlds, if you believe) becomes chaotic and threatens to eliminate the entire human race for breaking the laws of physics.

But thats not what this show wants viewers to think. Physics is lame. Instead, it dives into the personal tragedies that lead the characters to make the decisions they do. They are museums of decisions. Their lives are ephemerides of emotion, and when they cross paths with another timeline via phone calls, they simultaneously recognize all of their mistakes while also changing the course of an entire world. Sure, were all just drops in an ocean, but Calls makes you feel like a ripple.

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How Easy Is It To Imagine Absolutely Nothing? – Walter Bradley Center for Natural and Artificial Intelligence

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The Big Bang is, for most, the beginning of all science questions about the universe and the mind and all that Many dislike the Big Bang because, while it is makes the best sense of the universe, it implies that there is a God. What are the arguments either way?

Some see the Big Bang as engineered, though not by a divine Mind.

Harvard astronomer Avi Loeb, argued in Scientific American last October that advanced aliens engineered the Big Bang and that, when we humans are sufficiently advanced, we will create other universes as well. Loebs hypothesis is not logically stranger than the many that attempt to account for the Big Bang without underlying information/intelligence.

It does not appear that the Big Bang had a natural beginning. It was the beginning. Before it, there was nothing at all, which is a hard concept for us to grasp. In a debate with naturalist philosopher David Papineau, theistic neurosurgeon Michael Egnor described it as an effect with no physical cause. Despite their other differences Papineau agreed with that.

Some have argued that there were multiple Big Bangs, each building on the ashes, so to speak, of the last. University of Birmingham philosophy prof Alastair Wilson attempts to explain the concept poetically, relying on cosmologist Roger Penrose,

For a philosopher of science, Penroses vision is fascinating. It opens up new possibilities for explaining the Big Bang, taking our explanations beyond ordinary cause and effect. It is therefore a great test case for exploring the different ways physics can explain our world. It deserves more attention from philosophers.

For a lover of myth, Penroses vision is beautiful. In Penroses preferred multi-cycle form, it promises endless new worlds born from the ashes of their ancestors. In its one-cycle form, it is a striking modern re-invocation of the ancient idea of the ouroboros, or world-serpent. In Norse mythology, the serpent Jrmungandr is a child of Loki, a clever trickster, and the giant Angrboda. Jrmungandr consumes its own tail, and the circle created sustains the balance of the world. But the ouroboros myth has been documented all over the world including as far back as ancient Egypt.

The ouroboros of the one cyclic universe is majestic indeed. It contains within its belly our own universe, as well as every one of the weird and wonderful alternative possible universes allowed by quantum physics and at the point where its head meets its tail, it is completely empty yet also coursing with energy at temperatures of a hundred thousand million billion trillion degrees Celsius. Even Loki, the shapeshifter, would be impressed.

Well, it sounds grand but, once we take our explanations beyond ordinary cause and effect, we lose the power of logic to evaluate them.

Neurologist Steven Novella offers another approach. Also hat tipping cosmologist Roger Penrose, outlines a theory by which the universe could have come about from nothing without a beginning by asking us to reimagine what nothing means. Perhaps there cant be nothing but the fact that the universe is expected to wind down until it undergoes heat death may be, he considers, a way out:

Perhaps the laws of reality (the metaverse, whatever) simply do not allow for a state that we would understand as completely nothing. We think of nothing as simply the absence of stuff, of matter and energy, but perhaps its more complicated than that. It may simply be impossible for there to be truly nothing in that simplistic sense. This, of course, deals with the ultimate nature of reality, where physics borders metaphysics.

What if the maximally expanded and cold universe mathematically approaches the identical state as the singularity that resulted in the Big Bang? Again, our human minds limited by the frame of the Earth cannot wrap around this concept, but we can crunch the numbers. At some point the heat death universe becomes a singularity, and then starts another cycle of the universe. If you want to really blow your mind, some physicists even speculate that this would be the same universe. Not another version of the same matter and energy, but the actual same universe in space and time. Essentially the end of the universe and the beginning of the universe are the same moment in time, the universe loops back in on itself in one giant self-contained temporal cycle.

The universe would then be temporally finite but unbound (Stephen Hawking discussed this in his book, A Brief History of Time). The best analogy is a ring, we just keeping going around the ring forever, but there is no true beginning or end. In this concept there is no beginning or end, there is no before, there is just a bound infinite loop. This solves the something from nothing problem, because the universe did not come from anything, it just always was. This still leaves us with the deeper question why is there something instead of nothing, but that may not be a useful line of inquiry.

In that case, the matter that makes up the universe must be assumed to be an eternal Something.

Novella places his trust in mathematics but its hard to know if we should trust mathematics if he is right.

In the beginning, the Lord created the heavens and the earth is a simpler explanation in that it has the advantage that God is not considered to be either the universe or part of the universe. Eternal existence is simply part of the nature of God. But that makes more sense for God than for the universe.

The non-theistic explanations are colorful but it is not clear that they solve problems. Rather, they demonstrate the difficulty we have imagining absolutely nothing.

You may also wish to read:

Freebits: An interesting argument from the Big Bang for free will There are two types of uncertainty, we learn, only one of which could create free will. Astrobiologist Caleb Scharf argues that information isnt just a way to probe the fundamentals of nature; it may be part of the fundamentals.

and

Round 3: Egnor vs Papineau: The Big Bang has no natural beginning, In the debate between theistic neurosurgeon Michael Egnor and naturalist philosopher David Papineau, the question gets round to the origin of the universe itself. Egnor maintains that the Big Bang, which is held to have created the universe, is an effect with no physical cause. Papineau agrees.

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