Monthly Archives: September 2021

Roundup: Adalimumab Biosimilar Advancements and a Biosimilar Pill – The Center for Biosimilars

Posted: September 17, 2021 at 9:06 pm

Alvotech of Reykjavik said it has received a recommendation for approval of its adalimumab biosimilar (AVT02) from the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency.

The approval concerns a high-concentration, citrate-free 100-mg/mL formulation of adalimumab, referencing Humira. The positive opinion from the CHMP will go to the European Commission, which is the authority that has the power to authorize marketing of the drug in the European Union and EU member states (Iceland, Liechtenstein, and Norway).

Adalimumab inhibits the activity of tumor necrosis factor, a protein in the body that causes inflammation. The drug is used in the treatment of multiple conditions, including Crohn disease, rheumatoid arthritis, and psoriatic arthritis.

Alvotech noted that Humira has annual sales of about $20 billion. AbbVie, the owner of the Humira franchise, has captured significant market share with its own high-concentration, citrate-free formulation, and Alvotechs product has the potential to take a portion of that business away from the drug company giant.

However, Alvotech would not be the first company to bring a high-concentration biosimilar of adalimumab to market in the European Union. Celltrion Healthcare achieved that milestone in February 2021 when it received European Commission approval to market Yuflyma, a 100-mg formulation.

Both Celltrion and Alvotech hope to gain FDA approval to market their high-concentration adalimumab biosimilars in the United States.

Biosimilar Adalimumab in New Zealand

New Zealands Pharmaceutical Management Agency (Pharmac), the government entity that decides which medicines are subsidized for use in hospitals and community settings, said it is contemplating making the adalimumab biosimilar Amgevita the principal adalimumab product in that country, displacing Humira, in February 2022.

Pharmac said the proposed change would save money. The list price of Amgevita would be lower than the current adalimumab list price, Pharmac said.

Amgevita is available in citrate-free formulation, which reduces pain on injection, and is dispensed in prefilled pens and syringes in doses of 20 mg/0.4 mL and 40 mg/0.8 mL; however, Pharmac said dosing restrictions would be removed for patients using Amgevita.

Higher concentration Humira is available, also in citrate-free formulations, and it was not explained whether the removal of dosing restrictions on Amgevita is intended to compensate for that. A public comment period on the proposal closes on September 22, 2021.

Patients who start on adalimumab treatment would automatically receive Amgevita, and those who are currently treated with Humira would have to switch to Amgevita by September 1, 2022. The Amgevita preference would continue at least through June 2026.

This proposal results from a competitive process for the principal supply of funded adalimumab. It would release significant funds for Pharmac to invest in other medicines for the benefit of New Zealanders, the government organization said.

Theres a (Biosimilar) Pill for That

BioFactura, a Maryland-based biopharmaceutical company, said it will partner with Rani Therapeutics to package its proposed ustekinumab biosimilar (BFI-751) in the form of a robotic pill that is ingested and delivers a drug payload into the small intestine via injection.

The ustekinumab biosimilar candidate would reference Stelara and be used in the treatment of Crohn disease, ulcerative colitis, plaque psoriasis, and psoriatic arthritis. Ustekinumab reduces inflammation that causes these conditions.

The robotic pill concept, if successful, would substitute for subcutaneous or intravenous administration, BioFactura said. The RaniPill capsule is designed to be a pain-free alternative for delivering large molecule chronic disease treatments that are typically administered via injection, the company said.

Rani Therapeutics will conduct preclinical studies to determine whether pill administration is suitable for ustekinumab administration.

BioFactura Australia, the BioFactura subsidiary charged with development of BFI-751, initiated a phase 1 double-blind trial in April 2021 to compare pharmacokinetics, safety, and tolerability between the originator and biosimilar candidate agents.

Rani Therapeutics created a simulation video that demonstrates how the robotic pill would travel through the body to deliver a drug agent.

For Related Reading:

The Center for Biosimilars recently interviewed Anil Okay, chief commercial officer for Alvotech, about the company's biosimilar development and marketing plans. Okay explained why the company believes the high concentration formulation, AVT02, will have a marketing advantage.

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Roundup: Adalimumab Biosimilar Advancements and a Biosimilar Pill - The Center for Biosimilars

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Listen to I Don’t Live Here Anymore by The War on Drugs – Pitchfork

Posted: at 9:05 pm

Here is a song that will make you long to be back in a concrete arena filled with 20,000 new friends, singing together in a way that makes you think, if only for a moment, that humanity might not be swirling toward total catastrophe. You can feel the stick on the soles of your feet just by listening to this thing. You can smell the frankfurters. Its the type of anthem that makes one of those $18 Budweisers in a commemorative plastic cup seem like a damn bargaina small price to pay to briefly heighten some sense of communion after a year and a half of pandemic seclusion.

Everything about the title track to the War on Drugs upcoming fifth album is gloriously unsubtle, including its opening lines. I was lying in my bed/A creature void of form, sings bandleader Adam Granduciel, nodding to Dylan. Been so afraid of everything/I need a chance to be reborn. And honestly, who doesnt feel like that right now? Cue the synths reminiscent of Don Henleys Boys of Summer, the drums sparkling enough to make 80s stadium-rock guru Mutt Lange bow down in appreciation, and the gospel-tinged backing vocals that urge you to believe in something beyond yourself. Granduciel has been meticulously mining classic rock sounds for more than a decade, but never quite like this; his Springsteen fandom is well-documented (his young son is named Bruce) but hes never made a song as welcoming as Hungry Heart until now.

I Dont Live Here Anymore celebrates getting to the point in life when youre no longer drowning in waves of old memories but surfing atop them. The title is not a lament but a point of pride. Amid a daydreaming verse, Granduciel wonders, Is life just dying in slow motion/Or getting stronger everyday? Then a cascade of toms and guitars give way to the majestic hook, and the answer could not be clearer.

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14 Best Songs of Week: The War on Drugs, Hatchie, Sam Evian, Magdalena Bay, and More – Under the Radar Mag

Posted: at 9:05 pm

14 Best Songs of Week: The War on Drugs, Hatchie, Sam Evian, Magdalena Bay, and MorePlus Tonstartssbandht, Snail Mail, My Morning Jacket, Coco, Ducks Ltd., and a Wrap-up of the Weeks Other Notable New Tracks

Sep 17, 2021By Mark Redfern (with Joey Arnone)

Welcome to the 35th Songs of the Week of 2021. It was a blockbuster week for new songs, with lots of strong contenders. We tried to show a bit of restraint and keep it to an already over-stuffed Top 12, but then we just went for it with a Top 14. I mean, whose going to tell us we cant pick 14 favorite songs? Its our website and we have no corporate overlords.

In the last week we posted interviews with Madi Diaz and Jos Gonzlez.

In the last week we also reviewed a bunch of albums.

To help you sort through the multitude of fresh songs released in the last week, we have picked the 14 best the last week had to offer, along with highlighting other notable new tracks shared in the last seven days. Check out the full list below.

1. The War on Drugs: I Dont Live Here Anymore (Feat. Lucius)

The War on Drugs are releasing a new album, I Dont Live Here Anymore, on October 29 via Atlantic. On Wednesday they shared its second single, I Dont Live Here Anymore, which features backing vocals from Lucius and has a big bold 1980s rock sound. It was shared via an Emmett Malloy-directed video that features the band performing the song on a rooftop with the downtown Los Angeles skyline behind them (which is also very 1980s), among other things.

Previously The War on Drugs shared the albums first single, album opener Living Proof, via a video for it. Living Proof was #1 on our Songs of the Week list. Then they remotely performed Living Proof on The Late Show with Stephen Colbert.

I Dont Live Here Anymore is the follow-up to 2017s A Deeper Understanding (which won the 2018 Grammy for Best Rock Album and was our #1 album of 2017), although in 2020 they released a live album, simply titled LIVE DRUGS, via frontman Adam Granduciels own Super High Quality Records.

Sessions for the album began in early 2018, when Granduciel, bassist Dave Hartley, and multi-instrumentalist Anthony LaMarca recorded some demos in Upstate New York, including early versions of some of the songs on I Dont Live Here Anymore. But the album was recorded during more than 12 sessions, in seven studios (including Electric Lady in New York and Los Angeles Sound City), and over three years, with co-producer/engineer Shawn Everett helping to guide the ship. Living Proof was recorded in May 2019 at Los Angeles Electro-Vox studios with the bands entire lineupwith the aforementioned members joined by keyboardist Robbie Bennett, drummer Charlie Hall, and saxophonist Jon Natchez. A press release says that Granduciel puts War on Drugs records together like a kind of rock n roll jigsaw puzzle.

Read our review of A Deeper Understanding here.

Read our interview with the band about making A Deeper Understanding.

Read our interview with Adam Granduciel on recording A Deeper Understanding.

2. Hatchie: This Enchanted

On Tuesday Hatchie, the dream pop project of Australian musician Harriette Pilbeam, shared a new song, This Enchanted, via a video for it. It is her first single for Secretly Canadian and her signing with the label was also announced on Tuesday. This Enchanted again finds Hatchie ably putting a modern spin on early 90s shoegaze music, producing a song thats at once pleasing to old school fans of the genre but is also accessible to contemporary listeners with no proven affinity for shoegazers. The video finds Pilbeam wandering around a city at night while wearing angel wings, as well as showing her performing the song with her band.

This Enchanted is Hatchies first single since the 2019 release of her acclaimed debut album, Keepsake, which came out via Double Double Whammy. The song came together in February 2020, while Pilbeam and her romantic partner, and Hatchie guitarist, Joe Agius (who also releases music as RINSE) were writing in Los Angeles and working with producer Jorge Elbrecht (Sky Ferreira, Japanese Breakfast, Wild Nothing).

Pilbeam had this to say about the song in a press release: This Enchanted encapsulates everything I wanted to do moving forward from my first album. I started writing it with Jorge and Joe in February 2020 and completed it from afar in lockdown later in the year. We had been talking about making something dancey but shoegaze.

Its one of the more lighthearted, lyrically vague songs of my new recordings about falling in love; its not a perfect relationship, but youre enthralled by one another and its an easy love. Its one of the most fun songs Ive written, so it was a no-brainer to pick it as my first solo release in almost two years. It feels so right to be working with a label as exciting as Secretly as I step into new territory with Hatchie. Ive been counting down the days until its release for a long time.

Read our rave 8.5/10 review of Keepsake here.

Read our 2018 interview with Hatchie on her EP Sugar & Spice.

Read our My Favorite Album interview with Hatchie on Carole Kings Tapestry.

3. Sam Evian: Time to Melt

Sam Evian is releasing a new album, Time to Melt, on October 29 via Fat Possum. On Monday he shared its second single, title track Time to Melt, via a trippy video for it. John TerEick directed the video, in which Evian meets an alien in the woods. It was filmed in the woods near Evians house.

Evian had this to say about the song in a press release: If youre familiar with tarot, I think of it as pulling the death card in a positive way. Its like facing the idea of death, which I think everyone thought about a lot this past year, maybe more than usual collectively.

He had this to add about the video: I met a lonely alien in the woods and they taught me a jig. As the night went on they convinced me to try huffing some special kind of bug spray, which opened a wormhole vortex to another dimension.

Previously Evian shared Time to Melts first single, Knock Knock, via a video for it. Knock Knock was one of our Songs of the Week.

Evian recorded the album in his own studio, Flying Cloud Recordings, in a Catskills town in Upstate New York, where he lives with his romantic partner, fellow musician Hannah Cohen after decamping from New York City. The album was recorded during the pandemic and it features Cohen, as well as remote contributions from Spencer Tweedy, Chris Bear, and Jon Natchez (The War on Drugs).

Evians last album was 2018s You, Forever.

On tour Evian will be joined by Brian Betancourt (bass), Michael Coleman (keys), Sean Mullins (drums), and Liam Kazar (guitar, synths).

4. Magdalena Bay: You Lose!

Los Angeles-based electro-pop duo Magdalena Bay (aka Mica Tenenbaum and Matthew Lewin) are releasing their debut full-length album, Mercurial World, on October 8 via Luminelle. On Wednesday they shared its third single, You Lose!, via an amusing video that features the band having a series of unfortunate events, such as losing the ice cream off a cone or running out of toilet paper.

In a joint press release statement the band say the new single is about trying to be a musician and feeling like time for success is always running out. Its definitely melodramatic, describing ourselves as aging and nearing death, but sometimes it really feels that way.

Previously the band shared the albums first single, Chaeri, via a video. Chaeri was one of our Songs of the Week. Then they shared its second single, Secrets (Your Fire), via a fun video that features the band getting sucked into a computer. Secrets (Your Fire) was #1 on our Songs of the Week list.

Mercurial World is the follow-up to 2020s A Little Rhythm and a Wicked Feeling EP. The band wrote, produced, and recorded the album themselves.

We spend all of our time together, and in some ways Mercurial World is about that particular sense of madness in containment, Lewin said in a previous press release. We live together and make art together; this immerses you in our creative, insular universe.

5. Tonstartssbandht: What Has Happened

This week Tonstartssbandht (the brother duo of Edwin and Andy White) announced the release of their 18th album, Petunia, which will be out on October 22 via Mexican Summer. They subsequently shared a Case Mahan-directed video for the albums lead single, What Has Happened. Check out the albums tracklist and cover art here.

Mahan states in a press release regarding the new video: We shot a couple hundred feet of Super 8 in the hot Orlando sun. That nocturnal bird that showed up midday gave us permission to film a heavy subject on a beautiful afternoon. Not premeditated, everything seemed to fall into place much like the bands performances that are sometimes seemingly improvised.

The vast majority of Petunia was written and recorded by the duo at their home studio in Orlando between April and August 2020. It was mixed by Joseph Santarpia and Roberto Pagano at The Idiot Room in San Francisco.

The bands previous album, Sorcerer, came out in 2017 via Mexican Summer. By Joey Arnone

6. My Morning Jacket: Love Love Love

My Morning Jacket are releasing a new self-titled album on October 22 via ATO. On Tuesday they shared its second single, Love Love Love, which features a simple but universal message: The more you give yeah/The more you get now/Go tell it to the world. It was shared via a vibrant George Mays-directed video.

Previously My Morning Jacket shared the albums first single, Regularly Scheduled Programming, via a video for it. Regularly Scheduled Programming also made our Songs of the Week list.

My Morning Jackets frontman Jim James had this to say about Love Love Love in a press release: Love Love Love is trying to steer the ship away from everything Im talking about in Regularly Scheduled Programming, and speak toward positivity and pure love, finding truth within yourself and in the world around you.

James produced and engineered My Morning Jacket over two multi-week sessions at Los Angeles, CAs 64 Sound. A press release says that the band almost called it quits prior to recording the album, but were inspired by performing four shows in summer 2019, in particular two nights at Red Rocks Amphitheatre, that encouraged them to make a new album and keep going as a band.

I hope this album brings people a lot of joy and relief, especially since weve all been cooped up for so long, said James in a previous press release. I know that feeling you get from driving around blasting music you love, or even lying in bed and crying to the music you love. The fact that were able to be a part of peoples lives in that way is so magical to us, and it feels really good that were still around to keep doing that.

My Morning Jacket released a new album, The Waterfall II, just last year via ATO after announcing it only a few days earlier. The album was the long-awaited follow-up to 2015s The Waterfall and was recorded at the same time as that album. When The Waterfall was released it was said to be part one of a two-part album and five years later they delivered on that promise. While no pre-release singles from the album were shared, when the album was released Feel You and Wasted both made our Songs of the Week list.

My Morning Jacket are currently on their first full on headline tour in five years. The band are partnering with PLUS1 so that $1.00 from every ticket will go to support non-profits working for environmental justice, racial equity, and securing access to mental health care for all.

In 2019, James released The Order of Nature, a new live album recorded with The Louisville Orchestra in collaboration with conductor/arranger/composer Teddy Abrams, via Decca Gold.

Read our interview with Jim James on the 2018 midterm elections.

Read our review of The Waterfall.

Read our interview with My Morning Jacket on The Waterfall.

7. Snail Mail: Valentine

On Wednesday Snail Mail (aka Lindsey Jordan) announced the release of her sophomore studio album, Valentine, which will be out on November 5 via Matador. Jordan also shared a new Josh Coll-directed video for the albums title track and announced a new 2021/2022 tour. Check out the albums tracklist and cover art, as well as the list of tour dates, here. The video is age restricted and can only be watched on YouTube, so weve also included the basic audio of the song.

Jordan speaks about the new album in a press release, stating: I wanted to take as much time as possible with this record to make sure I was happy with every detail before unleashing it unto yall. Referring to the process as the deepest level of catharsis and therapy I have ever experienced would be a huge understatement. Valentine is my child!

She adds, regarding the Valentine video: It was so rewarding concocting this video alongside the brilliant Josh Coll! Watching a few perverse images in my head metamorphose into this gorgeous storyline and eventually into a tangible visual was one of the most rewarding experiences of my life. We connected over a mutual interest in the intersection between terror and devastating beauty. But also Tim and Eric and watered down ginger ale, which I had to drink a shocking amount of in those drink-bombing scenes.

Valentine was written and produced by Jordan and co-produced by Brad Cook (Bon Iver, Waxahatchee). Jordans debut album as Snail Mail, Lush, came out in 2018.

Read our interview with Snail Mail on Lush. By Joey Arnone

8. Coco: Come Along

This week Coco, a trio consisting of Maia Freedman (Dirty Projectors), Dan Molad (Lucius), and Oliver Hill (Pavo Pavo), shared a video for their new single titled Come Along. It is the latest release from their forthcoming self-titled debut studio album, which will be out on October 29 via First City Artists/Awal.

The band states in a press release: The skeleton of Come Along was recorded live, all together, with Oliver on guitar, Maia on drums, and Danny on bass. The underlying chord loop plays throughout as other instruments are weaved in one by one, picking up momentum and rolling forward as everything joins in harmony. The video mimics the song in this way, portraying our individual days-in-the-life with each of us filming one another on handheld camcorders. The day culminates in our first performance together as Coco, at a house show in Olivers garage with our friends as backing band. When it all came together we were pleased with the juxtaposition of the comically low fidelity and fast-paced editing, like a homemade action movie. Just as releasing music anonymously felt natural in 2020, it now feels natural to share ourselves and delight in the connection we make with our listeners.

Last year, Dirty Projectors shared an EP anthology album, 5EPs, via Domino. By Joey Arnone

9. Still Corners: Heavy Days

On Tuesday Still Corners shared a new single titled Heavy Days. The duo also announced a new 2022 U.S. tour in tandem with a set of rescheduled Europe dates. Check out the tour dates here.

Frontwoman Tessa Murray talks about the new song in a press release, stating: Sometimes it all feels like too much, theres a lot to take in reading the news all the time. We wanted to write a reminder to put the phone down now and again and get out there and live life to the fullest while you can.

The bands most recent album, The Last Exit, came out earlier this year on their own Wrecking Light label. By Joey Arnone

10. Ducks Ltd.: Under the Rolling Moon (Feat. The Beths)

Toronto-based duo Ducks Ltd. are releasing their debut full-length album, Modern Fiction, on October 1 via Carpark. On Tuesday they shared its third single, Under the Rolling Moon, which features backing vocals from labelmates The Beths. It was shared via a video featuring the band in a Hearse in the desert. Ambar Navarro and Max Flick directed the video and they were aiming for the feel of a low to mid budget video from 1985, such as some of the videos by The Cure.

The band features Evan Lewis on lead guitar and Tom McGreevy on vocals and rhythm guitar.

Under the Rolling Moon is about trying to be there for a friend who is in a moment of crisis, says McGreevy in a press release. Some of the frustration maybe of witnessing someone elses extremely recognizable self-defeating behavior, but mostly just the feeling of caring for them, knowing they can be ok and hoping that they can find their way to seeing that.

Previously the band shared its first single, 18 Cigarettes, via a video for it. 18 Cigarettes was one of our Songs of the Week. Then they shared its second single, How Lonely Are You?, which features labelmates The Beths. How Lonely Are You? also landed on our Songs of the Week list.

Modern Fiction follows their Get Bleak EP, which was originally put out in 2019 and given an expanded reissue by Carpark this past May. It included the new song, As Big As All Outside.

Producer James Cecil (The Goon Sax, Architecture in Helsinki) put finishing touches on the album and Carpark labelmates The Beths did backing harmonies on three of the albums songs. 18 Cigarettes features Eliza Neimi on cello.

11. Absolutely Free: Remaining Light

Torontos Absolutely Free are releasing a new album, Aftertouch, on September 24 via Boiled Records. This week they shared its second single, the Pink Floyd-esque Remaining Light.

The band collectively had this to say about the new single in a press release: Remaining Light expresses the frustration felt towards invincible and corrupt institutions that uphold structural inequities, including police brutality and manufactured poverty experienced primarily by racialized communities. Written during a heat wave in the summer of 2016, the song dishearteningly remains as relevant as ever today.

Previously Absolutely Free shared the albums first single, How to Paint Clouds, via a video for it made via an AI system.

Aftertouch is the bands first full-length album in seven years. Jorge Elbrecht produced the album, which a press release describes as such: Culling from a myriad of influences that span Krautrock, New Wave, the proliferation of international psychedelic and funk compilations, and early forms of electronic dance music, Absolutely Free has created a patina of disparate but harmonic styles distinctly its own.

Aftertouch follows the bands excellent 2019 EP, Geneva Freeport. That EPs first single, Currency (Extended Mix), which featured U.S. Girls (aka Meghan Remy), was one of our Songs of the Week. Its title track also made our Songs of the Week list, as did The Endless Scroll.

Absolutely Free havent released a full-length album since their 2014-released self-titled debut album. The bands core lineup is Moshe Fisher-Rozenberg, Michael Claxton, and Matt King.

12. Makthaverskan: This Time

This week Swedish post-punk band Makthaverskan announced the release of their fourth studio album, Fr Allting, which will be out on November 12 via Run For Cover. They also shared the albums lead single, This Time. Check out the albums tracklist and cover art here.

Fr Allting features production by Hannes Ferm (HOLY), as well as the incorporation of drum machines and synthesizers, something previously not used by the band. Guitarist Hugo Randulv states in a press release: When we started the songwriting process for this album, I think we all were pretty determined to take the music in a new direction. Not necessarily that we would sound different, but to work on the songs using somewhat different methods than before. For our previous albums, we wrote the songs in our rehearsal space and pretty much recorded them the way they were. For this album, we intended the songs to be finalized in the studio and left some more room to work with.

The bands most recent album, III, came out in 2017 via Luxury/Run For Cover. By Joey Arnone

13. Marissa Nadler: If I Could Breathe Underwater (Feat. Mary Lattimore)

Marissa Nadler is releasing a new album, The Path of the Clouds, on October 29 via Sacred Bones and Bella Union. On Tuesday she shared its second single, If I Could Breathe Underwater, via a video for the song that fittingly features Nadler underwater. The song features harp playing from Mary Lattimore, a longtime friend of Nadlers. Jenni Hensler directed the video, which was partially shot with 16mm film camera.

Nadler had this to say in a press release: When I wrote If I Could Breathe Underwater, I was contemplating the possibilities of possessing various superhuman powers: teleportation, shapeshifting, energy projection, aquatic breathing, extrasensory perception, and time travel to name a few. As a lyrical device, I married those powers with events in my life, wondering if and how they could change the past or predict the future. I loved working on the melody for this song and bringing the choruses to their climaxes. Marys layered, hallucinatory shimmers really echo the netherworld of the story.

Hensler had this to say about the video: This song took on many meanings to me and I love that about it. How beauty and tragedy collide. Dreaming of having supernatural powers to change reality and have the ability to live and breathe underwater. It could also speak to the duality of existence. That we all have inner personas or shadow selves, and how we envision those different masks we wear. I chose to make something that touched on the idea of duality and the inner persona. To connect to the two worlds.

Previously Nadler shared the albums first single, Bessie, Did You Make It?, via a video for it. Bessie, Did You Make It? was also one of our Songs of the Week.

Nadler wrote and recorded the album during the pandemic and was partially inspired by binging reruns of Unsolved Mysteries as she began to notice parallels between many of its stories and her own life, as a press release puts it. On The Path of the Clouds she worked with various collaborators, including Mary Lattimore, Simon Raymonde (of Cocteau Twins and Lost Horizons and the head of Bella Union), multi-instrumentalist Milky Burgess, Jesse Chandler (Nadlers piano teacher and a member of Mercury Rev and Midlake), Emma Ruth Rundle, and Black Mountains Amber Webber. Seth Manchester (Lingua Ignota, Battles, and Lightning Bolt) mixed the album.

Nadlers last album was 2018s For My Crimes.

14. Dean Wareham: Cashing In

Dean Wareham (of Luna, Galaxie 500, and Dean & Britta) is releasing a new solo album, I Have Nothing to Say to the Mayor of L.A., on October 15 via Double Feature. Today he shared its next single, Cashing In, in which Wareham sings Im not selling out/Im cashing in. Leanna Kaiser directed the accompanying video.

Wareham had this to say about the new single in a press release: Musically I was inspired by Michael Rothers great, late-70s instrumental guitar records. And also by Peter Hook; I played the new Hooky 6-string bass I bought last year, its a big part of that early New Order sound.

Previously Wareham shared the albums first single, The Past Is Our Plaything, via a video for it. The Past Is Our Plaything was also one of our Songs of the Week.

Warehams last solo album was 2014s Dean Wareham but since then hes kept busy, including doing the soundtrack for Mistress America with his wife, Britta Phillips, and reuniting and touring with Luna.

The hard thing is just to start, Wareham says of the gap between solo albums. When I sat down and did it, the songs came pretty quickly.

Papercuts Jason Quever produced and played on the album, which also features Phillips on bass, vocals, and keys, and Roger Brogan on drums.

In terms of the albums title, I Have Nothing to Say to the Mayor of L.A., and what he would say if he actually met the mayor of Los Angeles, where Wareham and Phillips have been based since 2013, Wareham responds: Its gonna happen. But the answer is right there tooI have nothing to say.

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14 Best Songs of Week: The War on Drugs, Hatchie, Sam Evian, Magdalena Bay, and More - Under the Radar Mag

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The War On Drugs release new single ‘I Don’t Live Here Anymore’ – Far Out Magazine

Posted: at 9:05 pm

American indie rock band The War On Drugs have unveiled the title track for their upcoming fifth studio album I Dont Live Here Anymore.

The track features Lucius vocalists Jess Wolfeand Holly Laessig backing up lead vocalist Adam Granducie during the choruses. The song itself is a dreamy mix of synths and guitars. Sounding quite a bit like the background music in The Breakfast Club, the amount of echo and gated reverb on the track is prime 1980s territory.

The band had previously mentioned that the LP would be an uncommon rock album about one of our most common but daunting processesresilience in the face of despair. Were starting to get a clearer picture of what thats going to look like, and good news: it comes with Bob Dylan references!

When we went to see Bob Dylan/We danced to Desolation Row/But I dont live here anymore/But Ive got no place to go. Do people actually dance to all eleven minutes of Desolation Row or was that just a convenient rhyme? Either way, it gives old school music nerds like me something to think about.

The War On Drugs actually have strong ties to Bob Dylan. Granducie is an avid fan, and when he met fellow musician Kurt Vile, the two bonded over their shared love for the singer, eventually leading to the formation of The War On Drugs. The band shared their cover of Tangled Up In Blue before, and their continued reverence of Dylan is easily found in their latest song.

Check out the video for I Dont Live Here Anymore down below. I Dont Live Here Anymore will be released on October 29.

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The War On Drugs release new single 'I Don't Live Here Anymore' - Far Out Magazine

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Call to abandon ‘failed’ war on drugs as report reveals death count in Lanarkshire for first half of year – Daily Record

Posted: at 9:05 pm

Its time to abandon the failed war on drugs and stop criminalising those who use them, according to an MSP.

The call from Gillian Mackay, Scottish Greens health and social care spokesperson, came as it was revealed there were a total of 67 suspected drugs deaths in Lanarkshire during the first half of this year.

The MSP also called for drugs legislation in Scotland to be devolved.

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The sad statistic of 67 suspected deaths in Police Scotlands Lanarkshire division area is the second highest of any in the country, exceeded only by the Greater Glasgow division.

The newly released figures by the Scottish Government compiled from police management information has revealed that the number of people who died from suspected drugs deaths in Lanarkshire for the latest quarter April to June 2021 was recorded as 29. Thats in addition to the 38 people who died in the first quarter of the year.

Although the number for the latest quarter is down significantly from the 53 who died in the same period last year, Ms Mackay believes its time for powers over drugs legislation to be devolved to the Scottish Parliament.

The Central Scotland MSP also called for safe drug consumption units to be exempt from prosecution in the meantime.

She said: This is a public health crisis. Health is devolved to the Scottish Parliament and powers over drugs legislation should clearly also be devolved so we can abandon the failed war on drugs and focus on harm reduction.

"We need action now, however, and the new Lord Advocate should use her authority to exempt lifesaving services such as safe drug consumption rooms from prosecution. The Minister for Drug Policy has said that work is underway on this issue and it is vital that meaningful progress is made.

Police Scotland compiled the latest data on the basis of reports from police officers who attended the scene of someones death. A suspected drug death is based on an officers observations and initial enquiries at the scene.

The statistics also show that there were 722 suspected drug deaths across Scotland in the first half of 2021.

That total is down slightly from the 731 people suspected to have died from drugs in the first six months of last year.

Glasgow City was again the hardest hit by far with 95 deaths in the latest quarter, to add to the 92 in the first three months of the year.

These figures remind us of the devastating impact that drug-related deaths continue to have on communities and families in Lanarkshire and Scotland as a whole, Ms Mackay said.

Too many people who use drugs are still being failed by the Scottish and UK Governments. We need to stop criminalising and stigmatising people who use drugs and take a more compassionate approach which recognises their right to dignity and treatment.

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Call to abandon 'failed' war on drugs as report reveals death count in Lanarkshire for first half of year - Daily Record

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A gem of a lab will design next-generation diamond sensors, bringing the world of quantum physics into the light – Newswise

Posted: at 9:03 pm

Newswise The novel design for a next-generation diamond sensor with capabilities that range from producing magnetic resonance imaging (MRI) of single molecules to detecting slight anomalies in the Earths magnetic field to guide aircraft that lack access to global positioning systems (GPS) will be developed by a collaboration of scientists led by the U.S. Department of Energys (DOE) Princeton Plasma Physics Laboratory (PPPL).

Leading the collaboration to develop a new quantum sensor, under a highly competitive three-year, $5.2-million award from the DOE, is David Graves, PPPL associate laboratory director for low temperature plasma surface interactions, who will work closely with co-designers Nathalie de Leon of Princeton University, a renowned expert in quantum hardware, and physicist Alastair Stacey of Australias Royal Melbourne Institute of Technology (RMIT).

"Technologies of tomorrow"

The award was one of 10 critically reviewed DOE microelectronic grants for national laboratories. Microelectronics are the key to the technologies of tomorrow, said Secretary of Energy Jennifer M. Granholm, and with DOEs world-class scientists leading the charge, they can help bring our clean energy future to life and put America a step ahead of our economic competitors.

The award brings PPPL, traditionally a fusion-focused research lab, fully into the often-bizarre world of quantum physics. This is the start of a whole new activity for the laboratory that will make us leaders in the use ofplasma to make diamond to improve sensors, said Steve Cowley, PPPL director. It is also a marvelous example of how the laboratory, under David Gravess leadership, iscollaborating with Princeton University and Professor Nathalie de Leon and physicist Alastair Stacey in Melbourne.

Creation of diamond sensors calls for the synthesis of designer diamond material that begins with a diamond seed that is built up through the gradual deposition of plasma-enhanced vapor. The trick is to replace carbon atoms of the growing material with nitrogen atoms and vacant spaces a combination referred to as NV centers in diamonds. This combination creates the sensor and is commonly called a color center since it glows red when a light shines on it.

Tricky materials design

The tricky materials design requires the exquisitely careful doping, or implantation, of nitrogen atoms together with the creation of vacant spaces in the color center. The doping is done with microwave reactors that produce the plasma-enhanced vapors that enlarge the diamond. These reactors are in some ways similar to the microwave ovens used in homes but are modified to enable them to ignite plasmas. Such reactors are very touchy and peculiar, Graves said. You have to do the process just right to get the doping to work.=

The PPPL venture will follow the pathway suggested by Stacey of Australias RMIT, who explained thatincreasing the number of color centers addressed at a time will make the sensor more sensitive.However, he said, the traditional methodofdoing this byincreasing the densityof the centerscreates defects in the diamond that degrade the color center properties and thus limit the sensor improvement.To avoid that problem, he proposed adding the innovative step of co-doping the diamond with phosphorus plasma to increase the density without electrical interference.

The plasma must be carefully controlled to successfully incorporate both dopants and that requires significant advances in plasma physics and chemistry. Key plasma researchers include PPPL physicists Yevgeny Raitses and Igor Kaganovich, leaders of PPPLs Laboratory for Plasma Nanosynthesis, who will examine plasma used in the synthesis of diamond sensors. Plasma, the fourth state of matter that makes up 99 percent of the visible universe, consists of free electrons and atomic nuclei, or ions.

Room-temperature plasmas

Kaganovich and his team will model the room-temperature plasmas and perform quantum-chemistry calculations of diamond growth, while Raitses will use state-of-the-art diagnostics to measure the chemical species, or substances, in the plasma. The plasma studies will help guide the choice of synthesis conditions. The low-temperature, or cold, plasmas studied compare with the million-degree fusion plasmas that have been the hallmark of PPPL research.

The basic idea is to combine plasma science with modeling the surface chemistry of the plasma and doing experiments to grow the diamond, Graves said. We also want to understand the science behind how you build and operate a plasma reactor to give you this highly specialized and defect-free material for useful quantum sensors.

The plan calls for buying two commercial reactors to co-dope the diamond at PPPL: one for light phosphorous doping and one for heavy phosphorous doping. The combination will enable a range of doping concentrations, Graves said.

The development process will bring all collaborators together. The group headed by Princetons de Leon will lead measurements that include what are called the coherence properties of the diamonds color centers. Such properties refer to the length of time that electrons in the color center spin in quantum superposition, or simultaneously up and down, to activate the sensor.

"Tight collaboration"

Having a tight collaboration between diamond synthesis, plasma modeling, and quantum measurement will enable a new frontier in quantum sensors, de Leon said. These research areas are typically completely separate research communities, and I am excited about what we can achieve together.

Meanwhile, Stacey will lead measurements of the doping characteristics and growth of the diamond crystal, beginning with the seed. The seed is a piece of existing high-purity single= crystal diamond, Stacey said. We often only add a tiny bit of new diamond, just as a new layer on the surface, but this new layer has precisely engineered properties [such as doping agents and increased densities] which the original seed did not have.

Graves notes the significance of the project for PPPL. This is a big step, he said. Its our first competitive [quantum] proposal. Its a pretty big deal for PPPL to get a grant in an area like this that is so different from our traditional research, and I think symbolically its important.

PPPL, on Princeton University's Forrestal Campus in Plainsboro, N.J., is devoted to creating new knowledge about the physics of plasmas ultra-hot, charged gases and to developing practical solutions for the creation of fusion energy. The Laboratory is managed by the University for the U.S. Department of Energys Office of Science, which is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, visitenergy.gov/science(link is external).

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A gem of a lab will design next-generation diamond sensors, bringing the world of quantum physics into the light - Newswise

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Are we approaching quantum gravity all wrong? – Big Think

Posted: at 9:03 pm

Electrons exhibit wave properties as well as particle properties, and can be used to construct images or probe particle sizes just as well as light can. Here, you can see the results of an experiment where electrons are fired one-at-a-time through a double-slit. Once enough electrons are fired, the interference pattern can clearly be seen. (Credit: THIERRY DUGNOLLE / PUBLIC DOMAIN)

At a fundamental level, we often assume that there are two ways of describing nature that each work well in their own regime, but that dont seem to play well together. On the one hand, we know that the matter and energy that makes up the Universe, from stars to atoms to neutrinos to photons, all require a quantum description in order to extract their properties and behavior. The Standard Model, the pinnacle of quantum physics, works perfectly well to describe every interaction weve ever measured in the Universe.

On the other hand, we also have General Relativity: our theory of gravity. However, this is fundamentally a classical theory, where the presence of matter and energy curves the fabric of space, and that curved space in turn tells matter and energy how to move through it. Although each one works quite well over its own range of validity, there are plenty of questions that require a thorough knowledge of both, together to answer. Due not only to their fundamental differences but their fundamental incompatibilities, many questions that we can imagine are currently beyond our ability to answer.

That doesnt necessarily imply that anything is broken with physics, but it certainly seems to indicate that our current understanding of matters is, at the very least, incomplete. In an attempt to uncover just what it is that we know, what we dont, and what the path forward might look like, I sat down in an interview with physicist Lee Smolin, wholl be appearing at the HowTheLightGetsIn festival in London this September 18 and 19. Lee is a pioneer in the field of quantum gravity and someone whose latest book, Einsteins Unfinished Revolution, details the search for what lies beyond whats presently known about the quantum Universe.

Ethan Siegel: What are the motivations behind why you would say quantum field theory and the Standard Model, and General Relativity for gravity, why can that not describe the Universe at a fundamental level?

Lee Smolin: Well it just cant. Its easy to think of experiments that that collection of ideas doesnt give consistent predictions for. More than that, there are reasons, in principle, why the principles that quantum physics is based on contradict the principles that General Relativity is based on, and we need to make these things fit together on a level of principle, because its supposed to be a fundamental theory of nature.

There are both experimental reasons and reasons of principle and between them there are also lots of technical problems that we see when we get to know them are a consequence of these conceptual clashes: clashes of principle.

ES: Can you give one example?

LS: Sure, what does collapse of the wavefunction, which is a part of quantum mechanics, look like in a spacetime which is dynamical, and which evolves according to some equations of motion in General Relativity?

ES: Einsteins original idea of unification was originally to geometrically add in classical electromagnetism to General Relativity, and we know that cant be right because we know the Universe is quantum mechanical in nature. You write about what you call Einsteins unfinished dream. Why is this dream important, even if Einsteins original ideas about it are no longer relevant?

LS: Well, I disagree with you about how relevant Einsteins original ideas were, for better or for worse. There are, in the history of science revolutions, where our understanding of nature changes profoundly and on every possible scale. When you go from being an Aristotelian scientist to a Newtonian scientist, your picture of the world changed drastically, on all scales, and there are many applications of that.

Heres what at stake. Einstein started two revolutions at the start of the 20th century: general relativity and quantum mechanics. He understood that they did not give a consistent picture put together. And in fact, he believed, and I agree with him, that quantum mechanics all by itself doesnt give a consistent picture. To put it directly, it just doesnt make sense: the quantum mechanics as it was formulated in the 1920s, by his friends and colleagues.

LS: So we have two tasks on the agenda. One is to make sense of quantum mechanics. And two is to fix that theory which is better than quantum mechanics, and to make that theory thats better than quantum mechanics also complete General Relativity. So I see it as a question of completion.

General Relativity covers very well, to a certain degree of approximation, certain phenomena. Quantum mechanics covers very well, to a certain degree of approximation, certain phenomena. Theyre both incomplete. Highly incomplete. At the level of experiments, you have to use some imagination, but its not all down at the Planck scale. There are experiments which involve timescales of minutes or seconds where we have no clear prediction. But this double revolution needs to be completed on both sides, and thats whats at stake: its to complete the revolution, because were living in a conceptual situation much analogous to that faced by Kepler and Galileo, who were contemporaries, they were each halfway between Aristotelian and Newtonian physics. They understood certain things very well, but they were deeply confused about other things. And thats our situation now.

ES: From the quantum side, Ive heard many people argue, counter to what youre arguing, that quantum physics works exactly fine for describing every quantum phenomenon in the Universe, so long as you dont also fold in quantum gravitational effects. If I can treat spacetime as being a classical or semi-classical background, then I can do everything that my quantum field theory predicts I should do without any errors or uncertainties. Do you disagree with that?

LS: Am I supposed to be impressed by that?

Aristotle worked with orbits and the positions of the planets that were accurate to a part in a thousand over a millennium. That was impressive, but it was bloody wrong. That simple-minded theory that youre describing why would somebody take such a little, little, low-ambitious thing? Of course you can make it work if you put in enough caveats and enough approximations, thats what were trained to do.

And there are some beautiful things that come out of it, like Steve Hawkings prediction of black hole radiation. So thats fine, but man, thats 1970s physics; do we want to do 1970s physics forever? Im being deliberately a bit provocative, but, you know, weve got to wake these people up!

ES: So I read, back in 2003, you co-wrote a paper [with Fotini Markopoulou] that showed what Ill say is an intriguing link between general ideas in quantum gravity and the fundamental non-locality of quantum physics. Now, maybe I should even ask you a setup question for this: we often state that quantum physics is fundamentally a non-local theory. And when we talk about quantum entanglement, we use that as sort of an illustration of that. But critics of that will say that no information ever travels faster than light from one quantum to another. Does this create any conflict in your mind? Would you say that quantum mechanics is fundamentally non-local?

LS: That quantum mechanics is fundamentally non-local, and therefore, making sense of quantum mechanics requires a strong modification in our understanding of what space is. And that General Relativity requires a strong modification in our ideas of what space is. And therefore, the things should go together. We shouldnt try to ignore that and do this and then ignore this and do that, we should fix them together, in one move. And thats what Ive been trying to do since 19 since I was in college.

That [paper], that was mostly [Markopoulous] idea, and that was a very clever demonstration of the principle that space could be is be emergent, so that time could be fundamental. And thats what she believed and she convinced me, and thats what Ive been working on, really, the last 20 years. Is the idea that time and causation are at the bottom, and are fundamental, and that space is a secondary, emergent quantity, like pressure of the air or temperature of the Earth. And so thats what weve been trying to do, and weve been having some moderate success along the road.

So that what we experience of the world, evolving in time event-by-event, event-by-event, is real, thats how the world really is. And out of that fundamental, active notion of time and causation, we make space as a derivative concept, the same way that out of the motion of atoms, you make a gas.

ES: Interesting. So you are very strongly an advocate that this classical notion of cause-and-effect, persists all the way down to the quantum level. I would assume that this means you are not a fan of quantum mechanics interpretations that do not maintain cause-and-effect as a fundamental tenet of all interactions?

LS: Mmm-hmmm, yes.

ES: I know that you have stated, and I dont know if its for ideological or physical reasons, that reality ought to be independent of us, the observer.

LS: Yes, of course.

ES: You say, yes, of course. And many people throughout the history of quantum mechanics have not thought, yes, of course. Can you explain why reality should be independent of the observer?

LS: Because Im a realist, and for me the goal of science is precisely the description of nature as it would be in our absence. Now, that doesnt mean that there isnt a role for the observer. For example, in the theories Ive been developing for the last five years its called the theory of views what is real in that Universe is a view of that Universe, looking back, causally, into the past. And thats exactly whats real. John Bell, who was very much a realist, used to say, we have to say not what the observables are, but what the viewables are. So Ive been developing this theory where we have events, and then have information or news that comes to them from the past, and thats whats real: those views. And the dynamics of the world doesnt depend on differential equations in space, or fields, it depends on the views, and the differences between those views. And the basic dynamical principle of the theory is that the Universe evolves to make the views as varied and as different from each other as possible.

ES: So you have a principle, then, of something thats either maximized or minimized.

LS: Of course.

ES: Is that something you could describe for us?

LS: Sure. Its called, the variety. It can be applied to many different kinds of systems, so lets take cities. Consider an old city: the center of Rome, which was preserved. Think of calling a friend and saying, Im lost, Im at some corner and heres what I see around me. Now, Rome is a city with a lot of variety, so your friend is gonna be able to say, Oh, youre there, near the [whatever] because every corner looks different. Rome is a city with high variety. On the other hand, there are some very suburban-dominated cities, in which you wouldnt know very much about where you are just from what you see when you look around, because many of the corners are similar to each other. So that can give you an example of what we mean when we say, we want to increase the variety.

ES: So when you say, we want to increase the variety, do you think that nature extremizes variety?

LS: Yes, and I can write that down as an equation within the framework I discussed, where there are these causal relations, and theres energy and momentum, but theres no space. We can construct a dynamical theory that extremizes, over time, the variety of the system. And we derive from that, quantum mechanics, and as a limit of that, classical mechanics.

Why do we get quantum mechanics out? Roughly speaking, there was an original realist interpretation of quantum mechanics called pilot wave theory, that Louis de Broglie invented in 1927, and it was reinvented by David Bohm in about 1952. And in that theory, theres potential energy and theres another new function of the wavefunction, and it sits where the potential energy usually sits. And they derive the Schrodinger equation from maximizing the influence of this function. Well, it turns out that this function that David Bohm invented is a certain limit of the quantity we call the variety, by the way with Julian Barbour, back in the 80s. And this was one of the great surprises of my working life.

ES: When you take this limit of the quantity you call the variety, and youre saying, were extremizing over that, this sounds to me like something that would be pretty analogous to some type of entropy, some type of thermodynamic quantity. So far, everyone I know whos tried to come up with a concept of gravity is emergent or space is emergent or some other quantity that we normally look at as fundamental is in fact emergent, takes something that in typical physics thought we view as emergent and makes that fundamental. I would say the typical view of physics is that entropy is an emergent property that you can calculate based on, say, the microscopic quantum state of all the particles aggregated together. Are you basically doing something similar to that, except with this thing you define as variety instead of entropy?

LS: Roughly speaking yes, but thats a long discussion. Because the role of entropy in cosmological theory is something we have to get our heads straight about. Theres a series of three very beautiful papers that Marina Corts, Andrew Liddle and Stu Kauffman have that weve been working on for a few years, and they contain some important new insights about very far-from-equilibrium systems and their relation to cosmology.

ES: Id like to ask about this idea that Heisenberg and a lot of other people had, which is that unless you have what we call an interaction in some sense one quantum interacting with another quantum thats the only thing that provides meaningful information about the Universe. If you dont make a measurement, then you dont have a quantifiable property of the Universe. So all of the information that we have has to come out of that act, which I look at, maybe naively, as fundamentally antagonistic to this idea of an objective reality. The fact that we cant make any measurements that discern between this Heisenberg-esque picture of reality and a objective reality exists picture of reality you have a certainty about your perspective that I dont share and that many physicists dont share. How do you make sense of this if you cant tell experimentally between these different interpretations?

LS: No, thats a fake. I dont know that, but its a good working fake. Let me tell you about how I look at quantum mechanics these days, because its new and its been very exciting to me. Our realization, actually following down some quotes of Heisenberg which were very mysterious at first, you know that Heisenberg said that the wavefunction description does not apply to the past. Somehow, the wavefunction was about the future, and the classical description is about the past. And a few people said this. Freeman Dyson said this at length; Schrodinger said something like that, and even deeper and more mysterious.

What we realized they were trying to say is that in the Copenhagen version of quantum mechanics, there is a quantum world and there is a classical world, and a boundary between them: when things become definite. When things that are indefinite in the quantum world become definite. And what theyre trying to say is that is the fundamental thing that happens in nature, when things that are indefinite become definite. And thats what now is. The moment now, the present moment, that all these people say is missing from science and missing from physics, that is the transition from indefinite to definite. And quantum mechanics, the wavefunction, is a description of the future which is indefinite and incomplete. And classical physics is how we describe the past.

Why? Because the past happened, what happened was definite, and it doesnt change, because its the past. So we have this different way of thinking about quantum mechanics, and it seems to be helpful, were having a good time.

ES: Its very hard to disagree with that. So when you look at, lets say, Wheelers delayed choice experiment. And Im thinking in particular of one where you send in a photon and you have a beam splitter, and the photon can take two paths around mirrors, and theyll meet up on the other side. And either youll have another beam splitter that will combine them and youll get your detector that will see an interference pattern of the recombined photons, or you wont put the splitter in there, and youll just get one of the photons that comes into your detector.

So, you can do this, and Wheelers idea is that you can send the photon through that first splitter, to have it go those two different ways. And then you can either put the second splitter there or not. And at the last second, you can either remove the splitter that was there (or not) or you can insert the splitter that wasnt there to try and, he called it, catch the photon deciding on what it was going to do before you made that measurement.

In hindsight, to no ones surprise, what did you measure at the detector? Well, if the splitter was there, you get the interference pattern back. And if the splitter wasnt there, youd just get the one photon back. Basically, nature doesnt know in advance what youre going to do. But once you do it, its like it knew all along what you were going to do. That, to me, and youre going to tell me thats not the only interpretation, has always meant the act of interacting, itself, is what gives you that meaningful information. If you didnt have any interactions taking place, you have not determined your reality yet. Your reality remains indeterminate until you make a measurement that would discern between the different possibilities.

LS: Yeah, but you see, I agree with that. Only, my line is now, is the boundary between the future and the past.

ES: Are you saying that right now, the in progress things, that have not yet been decided, that will be decided with an interaction at some point in the future, are you saying that everything in the past has already been determined, even those things where that measurement that will draw that line has not yet occurred?

LS: So that event has not yet occurred, so thats rather compatible. The notion of the now that gives rise to is not a thin instant, where it has to happen here; its what the philosophers call a thick now. So there can be events that turn something definite, that are late, or that are early, so our now can zigzag quite a bit. At least, thats the way we try to understand those cases. Theyre not in the original two papers, but were going through all these thought experiments in detail and show how to think about whats going on.

ES: This is stuff thats right on the cutting edge of trying to understand what the fundamental nature of reality is. Youve written very much, Id say, non-positively about many of the ideas in string theory, and how theyve become this dominant theoretical paradigm. One of the things Ive noticed about your work is that it seems to be relatively agnostic about other extensions to what might be out there: string theory, supersymmetry, grand unification, etc., you seem pretty agnostic about this all, which is maybe in contrast to what peoples public perception of you is.

LS: If people want to express an opinion about [my 2006 book, The Trouble With Physics], I would ask them the favor that they should read it. There was a lot of angst and conflict in that period, and I think people would be surprised here, but let me just tell you what I think. What I believe is that there are a number of interesting different approaches to quantum gravity, which so far are all incomplete. They all manage to explain something to us about what a quantum description of spacetime may be, but each of them also get stuck somewhere on some characteristic.

String theory is a beautiful set of ideas, which in my view has gotten stuck. And loop quantum gravity, which Im fortunate enough to have had the experience of working on while it was being invented, but its also clearly gotten stuck. Both of them express the same idea: that theres a duality between fields carrying forces, like the electromagnetic field, and quantum excitations of those fields can look like extended objects, like strings or loops, propagating. Both loop quantum gravity and string theory express in different contexts that fundamental conjecture.

What I tried to express in that book, and its always the authors fault when youre misunderstood, that book started as a case study of the role of conflict in science. Being a student of Paul Feyerabend, I think that conflict and disagreement are vital to the progress of science. And that book was meant to be an argument for that, using the case study that I knew best. As the book got shaped by me and by the editors, we flipped the book so that the case study came first and the analysis in terms of how the conflict plays a driving role in science came second, and most people only read the first half.

What I was against, and what I am against wherever I see it, is premature dogmatism: premature believing in something more than what the evidence supports. And this, unfortunately, is very common in science, because we all want to believe that weve done something good and discovered something. There was an atmosphere at the time, which I think is very dissipated now, of over-optimism in my view. I try to give a balanced view of what the strengths of string theory were and what the weaknesses were, and unfortunately some people reacted to that. But that was a long time ago.

ES: Can I ask you what you think of certain effective approaches to quantum gravity? Like asymptotically safe gravity, do you think that offers any promise? Ive always had an appreciation for that one because it seems to allow for predictions to be made in an otherwise inaccessible regime.

LS: Asymptotic safety has some very attractive points. Its basically an application by Steve Weinberg about some ideas about perturbatively non-renormalizable theories that Ken Wilson had, and he applied their ideas to gravity. Its a very attractive story, but theres a problem; as I said theres always a problem. The problem in asymptotic safety is unitarity. We know of an asymptotically safe theory which is present even in perturbation theory. Can we speak a little math here?

ES: Go ahead, Ill translate.

LS: The action principle to the theory is the Einstein action principle, plus the cosmological constant term, plus a term in the Ricci scalar squared plus a term in the Ricci tensor squared. And this last one invariably introduces instabilities and an impossibility to satisfy the principle of unitarity, which among other things means you cant guarantee that the probabilities for all the things that will happen will add up to one. And this has been a known problem since 1978 or 1982 or something, and I wrote the third paper in response to Steves paper that showed the violation of unitarity. So thats where it stands in my mind, but its always good to follow the kids, and theres a bunch of smart, young people working on this. Its not my bet, but its their bet, and theyre really good.

We dont have any senior faculty working on asymptotic safety at Perimeter, but we were so impressed by some of the young people who applied to us that, despite our own misgivings, we hired them for a few years. Because its interesting and exciting to have them around, and if you want your field to prosper, youve got to be able to listen to and promote young people who disagree with you, otherwise its not science.

ES: When Ive felt optimistic about it, Ive looked towards asymptotically safe gravity in the same way I now look back at the time-dependent Schrodinger equation. I say, okay, look, this has cases where it doesnt apply, and cases where it breaks down, because its not a relativistically invariant theory. But if you can find a formulation of it, like the Dirac equation, that is relativistically invariant, or if you could find a more general formulation, like quantum field theory that eliminates the need for that sort of thing. Maybe this idea can be salvaged, despite the fact that the way its formulated now, it doesnt guarantee unitarity.

LS: But if you turn it up so that it is giving you unitary answers to second or third order in perturbation theory, then the condition that there should be a non-trivial fixed point constrains the top quark mass by a measurable amount. They actually get a prediction that if this all works out, then heres the top quark mass.

ES: I remember reading a paper by Wetterich and Shaposhnikov years before they had measured the mass of the Higgs boson where they used the mass of all the particles except the Higgs to say, well, instead of getting the mass of the top were going to get the mass of the Higgs, and the value they got was ~126 1. But if I remember right, since then, the mass of the top has changed a little bit, and now if you put that same math back in, youd get something like 129 or 130, which doesnt agree with what theyve seen at the LHC.

LS: I didnt know that; thats interesting. Thats great. What else excites you?

ES: One thing Id like to press you on a little bit is this: if you have a dynamical spacetime, versus a static spacetime, how can you describe wavefunction collapse in a changing spacetime? If you have a wavefunction in a changing spacetime, what does wavefunction collapse look like, if your spacetime isnt static?

LS: Roger Penroses view of that is that the collapse of the wavefunction is a physical thing that happens when a certain measure of energy involved in that possible event is equal to the planck energy per planck time, or something like that. I dont remember the exact way he did it. So then, youre in a domain where neither the Einstein equation or the Schrodinger equation is quite right.

What Im really, really excited about is that there are some experiments under development where they actually test that. Theres a whole new generation of tabletop gravity or quantum gravity experiments that different people are working on.

ES: I like the tabletop experiments that are happening. One thing that I definitely wanted to ask you about is, youve talked, Ill say derisively about people who treat conclusions as if theyre foregone conclusions without having evidence to back that up. You want to remain open-minded to anything that may be possible before that critical evidence comes in. Do you worry that taking the stance of saying, I am a realist when it comes to quantum physics is violating that piece of advice. Do you worry about saying, Im a realist and I believe that reality is observer-independent is making that mistake?

LS: You know, I dont know whats wrong with me, but I love this stuff to death. I am having so much fun and theres nothing like it to be able to think about this stuff. Some people have this wire in them that says they have to be right, and I dont have that. I dont know why, maybe its a defect? So, sure, if you ask me, yeah, I could be wrong about that. I could be wrong about a lot of things.

Lets put us 1000 years in the future, well all look like fools for having missed the obvious things in neuroscience or planetary science or something that turned out to be important. There was a famous boxer who was asked how he felt about his career, and he said, you know, I did the best I could with what I was given. And Im happy with that. I dont gotta be right, but if I didnt follow what I believe in, I wouldnt be as happy a person now.

ES: I want to pull out a Niels Bohr quote and ask you your opinion of this, then. When we measure something, we are forcing an undetermined, undefined world to assume an experimental value. We are not measuring the world; we are creating it. This strikes me as a statement that I would expect you to fundamentally disagree with, but you might surprise me.

LS: No, it doesnt appeal to me, but wow, Im really sorry I never got to meet Bohr. He was an interesting guy; cant we just be on that level? In the end, Bohr was at a very weird place from our point of view in the development of western culture and society. He was influenced by Schopenhauer and people like that, and so he had what we would consider not just a non-realist viewpoint, but a radical non-realist viewpoint, and he did the best he could with that. But I dont believe that, that doesnt keep me up at night, but sure.

ES: Do you have any thoughts youd like to share that I havent asked you about that you think are too important to not share?

LS: Open up the scientific community to more people who are highly trained and really good. And maybe Im just getting this in because I like these ideas. For me, when people talk about diversity, that means not just women and blacks and aboriginals and who else, those are all very very important, but also very important are people who think differently. Now, to make a success in physics, you cant just be anyone off the streets, its like I couldnt compose a piece of music and send it to the New York Philharmonic and have them play it.

Youve gotta have your tools, youve got to be practiced, you gotta be good with your tools, youve gotta make a convincing case for the results that youve found in your work. Thats what a Ph.D. symbolizes But among the people who are excellent, technically, we want as wide a variety of ideas and viewpoints and types and personalities and gender and race its yes yes yes yes. I would hope that the next generation and the second-to-next generation live in a scientific world that is much more fun. Because if everyones like you, its not fun.

Lee Smolin will be appearing at the HowTheLightGetsIn London 2021 festival this September 18/19, with remaining tickets still available here.

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A gem of a lab will bring the world of quantum physics into the light – EurekAlert

Posted: at 9:03 pm

image:Co-doping diamond collaborators from left: Princeton Prof. Nathalie de Leon; David Graves, PPPL associate laboratory director for low temperature plasma surface interactions; Alastair Stacey of Australias Royal Melbourne Institute of Technology, with ultraviolet image showing emission from diamond color centers behind them. view more

Credit: From left: Sameer Khan/Fotobuddy; Elle Starkman/Office of Communications; photo courtesy of Alastair Stacey. Ultraviolet image courtesy of Science magazine; collage by Kiran Sudarsanan for Office of Communications.

The novel design for a next-generation diamond sensor with capabilities that range from producing magnetic resonance imaging (MRI) of single molecules to detecting slight anomalies in the Earths magnetic field to guide aircraft that lack access to global positioning systems (GPS) will be developed by a collaboration of scientists led by the U.S. Department of Energys (DOE) Princeton Plasma Physics Laboratory (PPPL).

Leading the collaboration to develop a new quantum sensor, under a highly competitive three-year, $5.2-million award from the DOE, is David Graves, PPPL associate laboratory director for low temperature plasma surface interactions, who will work closely with co-designers Nathalie de Leon of Princeton University, a renowned expert in quantum hardware, and physicist Alastair Stacey of Australias Royal Melbourne Institute of Technology (RMIT).

"Technologies of tomorrow"

The award was one of 10 critically reviewed DOE microelectronic grants for national laboratories. Microelectronics are the key to the technologies of tomorrow, said Secretary of Energy Jennifer M. Granholm, and with DOEs world-class scientists leading the charge, they can help bring our clean energy future to life and put America a step ahead of our economic competitors.

The award brings PPPL, traditionally a fusion-focused research lab, fully into the often-bizarre world of quantum physics. This is the start of a whole new activity for the laboratory that will make us leaders in the use ofplasma to make diamond to improve sensors, said Steve Cowley, PPPL director. It is also a marvelous example of how the laboratory, under David Gravess leadership, iscollaborating with Princeton University and Professor Nathalie de Leon and physicist Alastair Stacey in Melbourne.

Creation of diamond sensors calls for the synthesis of designer diamond material that begins with a diamond seed that is built up through the gradual deposition of plasma-enhanced vapor. The trick is to replace carbon atoms of the growing material with nitrogen atoms and vacant spaces a combination referred to as NV centers in diamonds. This combination creates the sensor and is commonly called a color center since it glows red when a light shines on it.

Tricky materials design

The tricky materials design requires the exquisitely careful doping, or implantation, of nitrogen atoms together with the creation of vacant spaces in the color center. The doping is done with microwave reactors that produce the plasma-enhanced vapors that enlarge the diamond. These reactors are in some ways similar to the microwave ovens used in homes but are modified to enable them to ignite plasmas. Such reactors are very touchy and peculiar, Graves said. You have to do the process just right to get the doping to work.=

The PPPL venture will follow the pathway suggested by Stacey of Australias RMIT, who explained thatincreasing the number of color centers addressed at a time will make the sensor more sensitive.However, he said, the traditional methodofdoing this byincreasing the densityof the centerscreates defects in the diamond that degrade the color center properties and thus limit the sensor improvement.To avoid that problem, he proposed adding the innovative step of co-doping the diamond with phosphorus plasma to increase the density without electrical interference.

The plasma must be carefully controlled to successfully incorporate both dopants and that requires significant advances in plasma physics and chemistry. Key plasma researchers include PPPL physicists Yevgeny Raitses and Igor Kaganovich, leaders of PPPLs Laboratory for Plasma Nanosynthesis, who will examine plasma used in the synthesis of diamond sensors. Plasma, the fourth state of matter that makes up 99 percent of the visible universe, consists of free electrons and atomic nuclei, or ions.

Room-temperature plasmas

Kaganovich and his team will model the room-temperature plasmas and perform quantum-chemistry calculations of diamond growth, while Raitses will use state-of-the-art diagnostics to measure the chemical species, or substances, in the plasma. The plasma studies will help guide the choice of synthesis conditions. The low-temperature, or cold, plasmas studied compare with the million-degree fusion plasmas that have been the hallmark of PPPL research.

The basic idea is to combine plasma science with modeling the surface chemistry of the plasma and doing experiments to grow the diamond, Graves said. We also want to understand the science behind how you build and operate a plasma reactor to give you this highly specialized and defect-free material for useful quantum sensors.

The plan calls for buying two commercial reactors to co-dope the diamond at PPPL: one for light phosphorous doping and one for heavy phosphorous doping. The combination will enable a range of doping concentrations, Graves said.

The development process will bring all collaborators together. The group headed by Princetons de Leon will lead measurements that include what are called the coherence properties of the diamonds color centers. Such properties refer to the length of time that electrons in the color center spin in quantum superposition, or simultaneously up and down, to activate the sensor.

"Tight collaboration"

Having a tight collaboration between diamond synthesis, plasma modeling, and quantum measurement will enable a new frontier in quantum sensors, de Leon said. These research areas are typically completely separate research communities, and I am excited about what we can achieve together.

Meanwhile, Stacey will lead measurements of the doping characteristics and growth of the diamond crystal, beginning with the seed. The seed is a piece of existing high-purity single= crystal diamond, Stacey said. We often only add a tiny bit of new diamond, just as a new layer on the surface, but this new layer has precisely engineered properties [such as doping agents and increased densities] which the original seed did not have.

Graves notes the significance of the project for PPPL. This is a big step, he said. Its our first competitive [quantum] proposal. Its a pretty big deal for PPPL to get a grant in an area like this that is so different from our traditional research, and I think symbolically its important.

###

PPPL, on Princeton University's Forrestal Campus in Plainsboro, N.J., is devoted to creating new knowledge about the physics of plasmas ultra-hot, charged gases and to developing practical solutions for the creation of fusion energy. The Laboratory is managed by the University for the U.S. Department of Energys Office of Science, which is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, visitenergy.gov/science(link is external).

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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UArizona Engineer Awarded $5M to Build Quantum-Powered Navigation Tools – The University of Arizona Research

Posted: at 9:03 pm

By Emily Dieckman, College of Engineering

Thursday

Zheshen Zhang, a University of Arizona assistant professor ofmaterials science and engineering, is leading a $5 million quantum technology project to advance navigation for autonomous vehicles and spacecraft, as well as measurement of otherworldly materials such as dark matter and gravitational waves.

The National Science Foundation'sConvergence Accelerator Program, which fast-tracks multidisciplinary efforts to solve real-world problems, is funding the Quantum Sensors project.

In September 2020, 29 U.S. teams received phase I funding to develop solutions in either quantum technology or artificial intelligence-driven data sharing and modeling. Ten prototypes have advanced to phase II, each receiving $5 million, including two projects led by UArizona researchers Zhang's project and another by hydrology and atmospheric sciences assistant professor Laura Condon.

"Quantum technology and AI innovation are a priority for the National Science Foundation," said Douglas Maughan, head of the NSF Convergence Accelerator program. "Today's scientific priorities and national-scale societal challenges cannot be solved by a single discipline. Instead, the merging of new ideas, techniques and approaches, plus the Convergence Accelerator's innovation curriculum, enables teams to speed their research into application. We are excited to welcome Quantum Sensors into phase II and to assist them in applying our program fundamentals to ensure their solution provides a positive impact on society at large."

Upgrading Gyroscopes and Accelerometers

The objects we interact with in our daily lives adhere to classic laws of physics, like gravity and thermodynamics. Quantum physics, however, has different rules, and objects in quantum states can exhibit strange but useful properties. For example, when two particles are linked by quantum entanglement, anything that happens to one particle affects the other, no matter how far apart they are. This means probes in two locations can share information, allowing for more precise measurements. Or, while "classical" light emits photons at random intervals, scientists can induce a quantum state called "squeezed" light to make photon emission more regular and reduce uncertainty or "noise" in measurements.

The Quantum Sensors project will take advantage of quantum states to create ultrasensitive gyroscopes, accelerometers and other sensors. Gyroscopes are used in navigation of aircraft and other vehicles to maintain balance as orientation shifts. In tandem, accelerometers measure vibration or acceleration of motion. These navigation-grade gyroscopes and accelerometers are light-based and can be extremely precise, but they are bulky and expensive.

Many electronics, including cellphones, are equipped with tiny gyroscopes and accelerometers that enable features like automatic screen rotation and directional pointers for GPS apps. At this scale, gyroscopes are made up of micromechanical parts, rather than lasers or other light sources, rendering them far less precise. Zhang and his team aim to develop chip-scale light-based gyroscopes and accelerometers to outperform current mechanical methods. However, the detection of light at this scale is limited by the laws of quantum physics, presenting a fundamental performance limit for such optical gyroscopes and accelerometers.

Rather than combat these quantum limitations with classical resources, Zhang and his team are fighting fire with fire, so to speak, by using quantum resources. For example, the stability of squeezed light can counterbalance the uncertainty of quantum fluctuations, which are temporary changes in variables such as position and momentum.

"The fundamental quantum limit is induced by quantum fluctuations, but this limit can be broken using a quantum state of light, like entangled photons or squeezed light, for the laser itself," said Zhang, director of the university's Quantum Information and Materials Group. "With this method, we can arrive at much better measurements."

Gaining an Edge on Earth and Beyond

The benefits of extremely precise measurements are numerous. If a self-driving car could determine its exact location and speed using only a compact, quantum-enhanced, onboard gyroscope and accelerometer, it wouldn't need to rely on GPS to navigate. A self-contained navigation system would protect the car from hackers and provide more stability. The same goes for navigation of spacecraft and terrestrial vehicles sent to other planets.

"In both space-based and terrestrial technologies, there are a lot of fluctuations. In an urban environment, you might lose GPS signal driving through a tunnel," Zhang said. "This method could capture information not provided by a GPS. GPS tells you where you are, but it doesnt tell you your altitude, the direction your vehicle is driving or the angle of the road. With all of this information, the safety of the passengers would be ensured."

Zhang is collaborating with partners at General Dynamics Mission Systems, Honeywell, the NASA Jet Propulsion Laboratory, the National institute of Standards and Technology, Purdue University, Texas A&M University, UCLA and Morgan State University.

"We are excited to work with the University of Arizona on this NSF Convergence Accelerator project," said Jianfeng Wu, Honeywell representative and project co-principal investigator. "The integrated entangled light sources can reduce the noise floor and enable the navigation-grade performance from chip-scale gyroscopes. The success of this program will significantly disrupt the current gyroscope landscape from many perspectives."

Because precise navigation would directly affect 700 million people worldwide, researchers estimate that quantum sensors could create a $2.5 billion market by 2035. They also expect that the precision and stability offered by the technology will give researchers a way to measure previously unmeasurable forces, such as gravitational waves and dark matter.

"As a leading international research university bringing the Fourth Industrial Revolution to life, we are deeply committed to advance amazing new information technologies like quantum networking to benefit humankind, said University of Arizona PresidentRobert C. Robbins. "The University of Arizona is an internationally recognized leader in this area, and I look forward to seeing how Dr. Zhang's Quantum Sensors project moves us forward in addressing real-world challenges with quantum technology."

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Vedika Khemani wins Breakthrough New Horizons Prize | Stanford News – Stanford University News

Posted: at 9:03 pm

Vedika Khemani, assistant professor of physics at Stanford University, has been awarded a New Horizons in Physics Prize from the Breakthrough Prize Foundation. Khemani was recognized for pioneering theoretical work formulating novel phases ofnon-equilibrium quantum matter, including time crystals.

Vedika Khemani (Image credit: Rod Searcey)

Time crystals got their name for the fact that, like crystals, they are structurally arranged in a repeating pattern. But, while standard crystals like diamonds or salt have an arrangement that repeats in space, time crystals repeat across time forever. Importantly, they do so without any input of energy, like a clock that runs forever without batteries. Khemanis work offered a theoretical formulation for the first time crystals, as well as a blueprint for their experimental creation. But she emphasizes that time crystals are only one of the exciting potential outcomes of out-of-equilibrium quantum physics, which is still a nascent field.

None of the world is in equilibrium; just look out your window, right? Were starting to see into these vastly larger spaces of how quantum systems evolve through experiments, said Khemani, who is faculty in the School of Humanities and Sciencesand a member of Q-Farm, Stanfords broad interdisciplinary initiative in quantum science and engineering. Im very excited to see what kinds of new physics these new regimes will bring. Time crystals are one example of something new we could get, but I think its just the beginning.

The $100,000 New Horizons Prize in Physics is given each year to up to three promising junior researchers who have already produced important work, according to the prize website. New Horizons prizes are one of three groups of Breakthrough Prizes in physics the others are the $3 million Special Breakthrough Prize and the $3 million Breakthrough Prize. The Breakthrough Prizes also recognize researchers in mathematics and life sciences. Called the Oscars of Science, the prizes are celebrated at a gala award ceremony presented by superstars of movies, music, sports and tech entrepreneurship. Since the prizes began in 2012, 10 Stanford faculty and researchers have won Breakthrough Prizes.

The concept of time crystals was first proposed in 2012 by physicist and Nobel laureate Frank Wilczek, but the idea was met with significant skepticism and comparisons to the impossible perpetual motion machine. In 2014, shortly after Wilczeks proposal, it was shown by Masaki Oshikawa and Haruki Watanabe that fundamental laws of thermodynamics provably forbid the existence of time crystals. (Watanabe is a co-recipient of the New Horizons Prize.)

Thus, Khemani wasnt thinking of time crystals at all as she went about her graduate work at Princeton University on non-equilibrium quantum physics. But in 2016, a reviewer for a preprint paper co-authored by Khemani pointed out that she and her colleagues had, without intending to, outlined a working model for time crystals.

I think if we had set out to find the time crystal we would have run into the same kinds of objections as Wilczek, said Khemani. Instead, we were thinking about: How do we generalize the ideas of quantum phases of matter to systems that are out of equilibrium?

Khemani and her doctoral advisor, Shivaji Sondhi, a professor of physics at Princeton University, were working on the problem of many-body localization. In a many-body localized system, particles get stuck in the state in which they started and can never relax to an equilibrium state. As such, these systems lie strictly outside the framework of equilibrium thermodynamics, which underpins our conventional understanding of all phases of matter.

Sondhi and Khemani worked with Achilleas Lazarides and Roderich Moessner at the Max Planck Institute to figure out how to think about phases of matter in many-body localized systems that are periodically driven in time, for instance by a laser. They found that, while equilibrium thermodynamics goes out the window, the possibility of formulating phases of matter need not. In addition to abstract theoretical formulations, they studied a concrete model: a periodically driven system of Ising spins. (The Ising model is often described as the fruit fly of statistical physics and has been extensively studied in equilibrium to understand fundamental phenomena, such as magnetism.)

These researchers found a number of phases in the out-of-equilibrium Ising model, including a novel one in which the system displays a stable, repetitive flip between patterns that repeat in time forever, at a period twice that of the driving period of the laser. (As required by the definition of time crystals, the laser does not impart energy into the system.) The phase Khemani and co-workers had found was, in fact, a time crystal the out-of-equilibrium setting in which they were working allowed them to evade the constraints imposed by the laws of thermodynamics.

In the months that followed the preprint, important properties about the new phase were worked out by Khemani and her collaborators, notably Curt von Keyserlingk at the University of Birmingham, as well as a by Dominic Else, Bela Bauer and Chetan Nayak at Microsoft Station Q. (Else and collaborators also independently identified Khemanis model as a time crystal, and Else is a co-recipient of the New Horizons Prize.) It was found that the phase displays a remarkable amount of robustness and stability. Then, various early experiments in 2017 showed promising precursors of the phase although they were ultimately found to not realize a stable many-body time crystal.

Khemani describes work in the years that followed as creating a checklist of what actually makes a time crystal a time crystal, and the measurements needed to experimentally establish its existence, both under ideal and realistic conditions.

In 2020, Matteo Ippoliti, a postdoctoral scholar at Stanford working with Khemani, and others published a proposal for experimentally realizing a time crystal using the unique capabilities of Googles Sycamore quantum computer. Following this proposal, this summer, Ippoliti and Khemani, collaborating with the large Google Quantum AI team, published a preprint paper detailing the experimental creation of the first-ever time crystal on Googles device. That paper is now undergoing peer review.

Khemani sees great promise in these types of quantum experiments for many-body physics.

While many of these efforts are broadly motivated by the quest to build quantum computers which may only be achievable in the distant future, if at all these devices are also, and immediately, useful when viewed as experimental platforms for probing new nonequilibrium regimes in many-body physics, said Khemani.

As for the award recognizing all of this work, Khemani described how it reflects the bigger picture. This is called the New Horizons prize and I do think we are looking at new horizons in physics, she said. There are people at Stanford who think about black holes and big astronomical questions talking to people who are trying to build quantum computers, talking to many-body theorists, talking to quantum information scientists. Its really exciting when you start getting so many different perspectives and so many different new ways of looking at problems.

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