The Prometheus League
Breaking News and Updates
- Abolition Of Work
- Ai
- Alt-right
- Alternative Medicine
- Antifa
- Artificial General Intelligence
- Artificial Intelligence
- Artificial Super Intelligence
- Ascension
- Astronomy
- Atheism
- Atheist
- Atlas Shrugged
- Automation
- Ayn Rand
- Bahamas
- Bankruptcy
- Basic Income Guarantee
- Big Tech
- Bitcoin
- Black Lives Matter
- Blackjack
- Boca Chica Texas
- Brexit
- Caribbean
- Casino
- Casino Affiliate
- Cbd Oil
- Censorship
- Cf
- Chess Engines
- Childfree
- Cloning
- Cloud Computing
- Conscious Evolution
- Corona Virus
- Cosmic Heaven
- Covid-19
- Cryonics
- Cryptocurrency
- Cyberpunk
- Darwinism
- Democrat
- Designer Babies
- DNA
- Donald Trump
- Eczema
- Elon Musk
- Entheogens
- Ethical Egoism
- Eugenic Concepts
- Eugenics
- Euthanasia
- Evolution
- Extropian
- Extropianism
- Extropy
- Fake News
- Federalism
- Federalist
- Fifth Amendment
- Fifth Amendment
- Financial Independence
- First Amendment
- Fiscal Freedom
- Food Supplements
- Fourth Amendment
- Fourth Amendment
- Free Speech
- Freedom
- Freedom of Speech
- Futurism
- Futurist
- Gambling
- Gene Medicine
- Genetic Engineering
- Genome
- Germ Warfare
- Golden Rule
- Government Oppression
- Hedonism
- High Seas
- History
- Hubble Telescope
- Human Genetic Engineering
- Human Genetics
- Human Immortality
- Human Longevity
- Illuminati
- Immortality
- Immortality Medicine
- Intentional Communities
- Jacinda Ardern
- Jitsi
- Jordan Peterson
- Las Vegas
- Liberal
- Libertarian
- Libertarianism
- Liberty
- Life Extension
- Macau
- Marie Byrd Land
- Mars
- Mars Colonization
- Mars Colony
- Memetics
- Micronations
- Mind Uploading
- Minerva Reefs
- Modern Satanism
- Moon Colonization
- Nanotech
- National Vanguard
- NATO
- Neo-eugenics
- Neurohacking
- Neurotechnology
- New Utopia
- New Zealand
- Nihilism
- Nootropics
- NSA
- Oceania
- Offshore
- Olympics
- Online Casino
- Online Gambling
- Pantheism
- Personal Empowerment
- Poker
- Political Correctness
- Politically Incorrect
- Polygamy
- Populism
- Post Human
- Post Humanism
- Posthuman
- Posthumanism
- Private Islands
- Progress
- Proud Boys
- Psoriasis
- Psychedelics
- Putin
- Quantum Computing
- Quantum Physics
- Rationalism
- Republican
- Resource Based Economy
- Robotics
- Rockall
- Ron Paul
- Roulette
- Russia
- Sealand
- Seasteading
- Second Amendment
- Second Amendment
- Seychelles
- Singularitarianism
- Singularity
- Socio-economic Collapse
- Space Exploration
- Space Station
- Space Travel
- Spacex
- Sports Betting
- Sportsbook
- Superintelligence
- Survivalism
- Talmud
- Technology
- Teilhard De Charden
- Terraforming Mars
- The Singularity
- Tms
- Tor Browser
- Trance
- Transhuman
- Transhuman News
- Transhumanism
- Transhumanist
- Transtopian
- Transtopianism
- Ukraine
- Uncategorized
- Vaping
- Victimless Crimes
- Virtual Reality
- Wage Slavery
- War On Drugs
- Waveland
- Ww3
- Yahoo
- Zeitgeist Movement
-
Prometheism
-
Forbidden Fruit
-
The Evolutionary Perspective
Monthly Archives: May 2021
Elon Tweets That Rawlinson Was Never Chief Engineer At Tesla, Except He Was – InsideEVs
Posted: May 4, 2021 at 8:09 pm
Oh, Elon. You weren't satisfied with only tweeting about your upcoming Saturday Night Live appearance today so you decided to take another dig at former Tesla employee and current Lucid Motors CEO and CTO, Peter Rawlinson. We guess you just couldn't help yourself and had to tell the world that Rawlinson was never the Chief Engineer at Tesla.
The problem is, it appears as Elon isn't remembering it the same way Rawlinson does. But since that could be a simple case of he said, he said, we took the time to dig up some old Tesla Blog posts, videos, and even a screenshot of the Tesla website when Rawlinson worked there, courtesy of the Wayback Machine.
Rawlinson and I have spoken about this exact topic in the past, and luckily I still have the recording of our conversation. Here's how the man behind the Lucid Air explains what went on when Musk hired him to save and deliver the Model S.
"Elon reached out to me and said, look, I've got a bloody disaster on my hands, will you come and join us? I joined the company and I checked out where they were at. I remember it vividly. After the first few days at Tesla, I went to see Elon at Space-X on a Friday and he asked me: What do you think? I said Elon, it's a disaster. You're going to have to start again. He asked everything? I said yes, look, I know how to do this, let me design Model S from scratch. Elon asked: What, you mean nothing (can be saved)? I said if you want the best car, then trust me, it's from scratch. I thought well, he can only fire me, but he didn't, he said do it - and he meant it. He actually trusted me and empowered me to do it and we did do it." - Lucid Motors CEO and CTO Peter Rawlinson on how he was tasked by Elon Musk to engineer the Tesla Model S.
We found these two videos in which Rawlinson explains Model S engineering. These identify Rawlinson as the "VP of Engineering", not specifically the Chief Engineer, as he is described in other places on the Tesla website.
Part 1:
And here's Part 2:
Below is the announcement that Rawlinson had joined the Tesla team as Chief Vehicle Engineer. You can find the full post on the Tesla blog from April 20th, 2010.
InsideEVs did reach out to Lucid Motors for comment, but it appears the company doesn't want to give this story any more oxygen than it already has. A company spokesperson replied:We have no comment to make at this time. As you will already be aware, Peters focus is on putting the worlds best EV into production, a car with over 500 miles of range that delivers new benchmarks in efficiency, power, range, performance, charge rate and luxury.
There's also this piece from the Tesla website that also names Rawlinson as the Chief Engineer for Vehicle Engineering.
Personally, I do love much of Elon's colorful personality. Sure, I think Elon (and Tesla) would be better off without some of his more outrageous statements, but overall, I believe his confident swagger was needed to get Tesla to where they are today.
That said, it appears that Elon misremembers Rawlinson's history with Tesla, or, even worse, he's guilty of creating some revisionist history. If what we've shown above isn't enough, check out this video of Rawlinson from the 2011 Detroit Auto Show. Additionally, we discovered this list of patents that Rawlinson and members of his team filed for, related to his work at Tesla.
We certainly don't mind some competitive banter between rival EV companies, but it's important to point out misinformation, which, after reviewing the information we found, seems to be the case. Take a look at the above information and let us know what you think in the comment section below.
See the rest here:
Elon Tweets That Rawlinson Was Never Chief Engineer At Tesla, Except He Was - InsideEVs
Posted in Elon Musk
Comments Off on Elon Tweets That Rawlinson Was Never Chief Engineer At Tesla, Except He Was – InsideEVs
Elon Musk’s next SpaceX flight will have private citizens as the crew | TheHill – The Hill
Posted: at 8:09 pm
Elon Musks SpaceX is aiming to take a giant leap in human spaceflight with its next mission.
The private rocket company is scheduled to send the first ever all-civilian crew into space as part of a flight scheduled for September.
America is changing faster than ever! Add Changing America to your Facebook or Twitter feed to stay on top of the news.
The Inspiration4 missionwill launch the four civilians into space where they will travel across a low Earth orbit on a multi-day journey that will continually eclipse more than 90% of the Earths population.
The civilian crew members include Jared Isaacman, an accomplished jet pilot and founder and CEO of Shift4 Payments; Hayley Arceneaux, a physician assistant; Sian Proctor, a teacher and communicator; and Chris Sembroski, an engineer at Lockheed Martin.
Isaacman, who will be commanding the mission, is funding the flight and arranged the mission as a fundraiser for St. Jude Childrens Research Hospital.
In fulfilling a personal and lifelong dream, I recognize the tremendous responsibility that comes with commanding this mission. While a historic journey awaits us in space, I hope this mission reinforces how far inspiration can take us and the extraordinary achievements it leads to here on Earth, Isaacman said.
On Sunday, SpaceXs Crew Dragon successfully carried NASA astronauts Michael Hopkins, Victor Glover and Shannon Walker, along with Japan Aerospace Agency astronaut Soichi Noguchi, back to Earth from the International Space Station.
The astronauts splashed down into the Gulf of Mexico just south of Panama City. The NASA Crew-1 astronauts had spent nearly six months in the International Space Stations (ISS) microgravity laboratory. The mission was the longest-ever duration for a crew launched in an American-built spacecraft.
SpaceX launched the crew to the ISS in November.
READ MORE STORIES FROM CHANGING AMERICA
FALSE ALARM: NO SPACE JUNK THREAT TO SPACEX LAUNCH
NASAS HELICOPTER SENDS FIRST AERIAL PHOTOS OF THE SURFACE OF MARS
ELON MUSKS SPACEX LAUNCHES NASA CREW-2 INTO ORBIT
FOR ITS NEXT TRICK, NASAS HELICOPTER FLEW SIDEWAYS ON MARS
NASAS MARS LANDER IS IN EMERGENCY HIBERNATION AND IT COULD DIE
Read more here:
Elon Musk's next SpaceX flight will have private citizens as the crew | TheHill - The Hill
Posted in Elon Musk
Comments Off on Elon Musk’s next SpaceX flight will have private citizens as the crew | TheHill – The Hill
Elon Musk’s fury with ‘knucklehead’ Bill Gates after shutting down ‘lovers’ claim – Daily Express
Posted: at 8:09 pm
Billionaire Microsoft founder Mr Gates and his wife, Melinda, are set to get divorced after 27 years. Announcing the news online, the couple said they made the decision after "a great deal of thought and a lot of work on our relationship, but will continue to work together on their foundation. Mr Gates, the fourth richest man in the world, married Melinda in January 1994, but stated that we no longer believe we can grow together as a couple in this next phase of our lives.
The 65-year-old is surpassed in wealth by only a handful of people in the world, including Mr Musk, but the pair have not always seen eye-to-eye.
They have both helped in the fight against COVID-19, with Mr Gates pledging $10million (7.21million) via the Bill and Melinda Gates Foundation and Musk redirecting Tesla resources to source and produce ventilators and teaming up with the German biotech firm CureVac of which Mr Gates is an investor.
Since last March, Mr Musk has appeared to downplay the severity of the virus, criticised stay-at-home orders and seemed to question death data.
In an interview on CNBC's "Squawk Box" last July, Mr Gates appeared to question his involvement.
He said: "Elon's positioning is to maintain a high level of outrageous comments.
"He's not much involved in vaccines. He makes a great electric car. And his rockets work well. So he's allowed to say these things.
I hope he doesn't confuse areas he's not involved in too much."
And that seemed to ruffle Mr Musk, who responded by posting multiple tweets, including "Billy G is not my lover" and "the rumour that Bill Gates and I are lovers is completely untrue.
During a podcast interview with the New York Times, his tone seemed more serious.
READ MORE:Dogecoin warning: Musk just flexing power muscles as DOGE tipped for turbulent twist
He said what Mr Musk has accomplished with Tesla is one of the greatest contributions to climate change anyone's ever made and added that underestimating Elon is not a good idea.
Since Mr Gates met his wife at his company, their organisation has spent billions fighting causes such as infectious diseases and encouraging vaccinations in children.
The pair, along with investor Warren Buffett, are also behind the Giving Pledge, which calls on billionaires to commit to giving away the majority of their wealth to good causes.
Mr Gates stepped down from Microsoft's board last year to focus on his philanthropic activities.
Read the original here:
Elon Musk's fury with 'knucklehead' Bill Gates after shutting down 'lovers' claim - Daily Express
Posted in Elon Musk
Comments Off on Elon Musk’s fury with ‘knucklehead’ Bill Gates after shutting down ‘lovers’ claim – Daily Express
Elon Musk Couldnt Get the Job He Wanted, So He Got Busy Changing the World – CleanTechnica
Posted: at 8:09 pm
Originally posted onEVANNEX.
Formany kids after college, getting a job isnt so easy. Even if youre Elon Musk. It turns out that Musk had failed in his efforts to land a job in the internetindustryback in 1995.
According toNews18, Musk, now known for revolutionizing the electric vehicle market, in fact had failed to get a job at Netscape Communications, the company that created the first web browser, when he first reached Silicon Valley in the 90s.
A Twitter user with the handle Pranay Pathole wrote that when Musk applied at Netscape, he went to their office but was so shy that he didnt talk to anyone and later wasnt able to get a job anywhere.
The last part of the tweet drew Musks attention and he promptlyreplied to correct his admirer. I could get a job, just not at an Internet company (werent many back then), Musk replied.
Did this setback stop Elon Musk? Obviously not. Its reported that, A year after failing at Netscape, Musk launched his own company, Zip2, which [was] aimed at helping media companies come online. Compaq bought the company in 1999 and Musk co-founded PayPal, which eBay acquired for $1.5 billion in July 2002.
After helping media outlets enter the online arena and birthing the first successful online payment system, Musk could have easily stopped there, counted his money, and retired young. Instead, he decided to take on the auto, energy, and aerospace establishment with Tesla, SolarCity, and SpaceX.
Musks audacity doesnt stop there either. Now hes trying to end soul-crushing traffic with The Boring Company. Hes also trying to help create a safe, symbiotic future with AI via Neuralink. And it all started because a young Elon was too shy in the front lobby at his dream job.
Read the rest here:
Elon Musk Couldnt Get the Job He Wanted, So He Got Busy Changing the World - CleanTechnica
Posted in Elon Musk
Comments Off on Elon Musk Couldnt Get the Job He Wanted, So He Got Busy Changing the World – CleanTechnica
The firm that connects Elon Musk, Rihanna, mixed martial arts and three Reliance Jio investors – Moneycontrol
Posted: at 8:09 pm
Dwayne "The Rock" Johnson, left, with Endeavor's Ari Emanuel and Patrick Whitesell at November 2015 event in New York City. (Ilya S. Savenok)
Its TIMEEEEEEEEEEE!!! Fans of combat sports would be familiar with this popular catchphrase of legendary Ultimate Fighting Championship (UFC) ring announcer Bruce Buffer.
In fact, this writer is one and wished Buffer, the Voice of the Octagon, was present when Endeavor finally walked into Wall Street.
Eighteen months after pulling the plug on its listing plans due to unfavourable market conditions, the entertainment powerhouse made its stock market debut earlier this week. Other than the mixed martial arts platform UFC, Endeavor is also home to the William Morris Talent Agency as well as sports and modelling agency IMG.
The Los Angeles-headquartered firm raised $511 million in a US initial public offering (IPO), valuing it at around $10 billion. The eagerly awaited offering has revived hopes in Hollywood of a revival in the entertainment, content and live events segments, which have been dealt vicious uppercuts by COVID-19.
In 2020, Endeavor clocked $3.5 billion in revenues and its losses stood at $625 million. Reducing the $5.9 billion debt burden is a high priority for the company.
Lets take a look at some interesting facts about the firm, its promoters, its investors and its deals.
The High-Profile Emanuel Siblings
The firms founder is Hollywood mogul Ari Emanuel,who loosely inspired the fictional character of Ari Gold in the hit HBO show 'Entourage.A New Yorker piece refers to Aris Chicagostyle aggression and how he craves the stature of a visionary, not of a mere corporate executive.
His elder brother Ezekeil Emanuel is an advisor to US President Joe Biden and a medical ethicist (an individual who advises hospital administrations on policies). The third siblingRahm Emanuel has been a White House chief of staff and mayor of Chicago.
A Celeb Client List To Die For.
Endeavors client portfolio includes some of the biggest names in showbiz, entertainment and sports. It has represented Hollywood celebrities like Dwayne The Rock Johnson, Martin Scorsese, Charleze Theron, Matt Damon and Christian Bale, sports stars such as Novak Djokovic, Serena Williams, Maria Sharapova, Lebron James and Stephen Curry, talk show hosts like Oprah Winfrey and even musicians like Adele and Rihanna. It doesnt get bigger than this folks.
The Elon Musk Factor
Tesla founder and the worlds richest man Elon Musk has been tapped by Endeavor to bolster its board of directors.
Founder Ari Emanuel and Musk have known each other for many years and Endeavor would be hoping that the social media savvy, billionaire tech entrepreneurs cult-like status amongst retail investors would widen the appeal of the newly listed entertainment conglomerate.
And perhaps, its Twitter following too. It also wouldnt hurt if its stock mirrored the incredible rally seen in the shares of Tesla over the last year.
The Reliance Jio Connection
US-based tech investor Silver Lake, which backs Twitter and AirBnb, is one of the early investors of Endeavor. The former shot into prominence after acquiring PC maker Dell Inc along with Micheal Dell in 2013. In 2011, Silver Lake sold Skype to Microsoft for $8.5billion in one of the most successful private equity exits in history. Private equity firm KKRand Middle East fund Mubadla are also investors in Endeavor.
Ok, so whats the link to Reliance Jio?
Well, interestingly, both firms have several common investors. Silver Lake, KKR and Mubadla participated in the 2020 fund-raising blitzkrieg by Jio, which raised a stunning $15 billion in 10 weeks by sealing 11 deals.
There was a sporty connection as well between the two groups. Reliance Industries owns the glitzy franchisee-based soccer league Indian Super League, which was launched in 2014 along with Endeavor arm IMG. IMG exited the league in 2018 by selling its stake to Reliance.
The Beautiful Deal With Donald Trump
Former US president Donald Trump was once a client of Endeavor. In 2015, the firm acquired Miss Universe Organization, which was solely owned by Trump and was responsible for producing Miss Universe, Miss USA and Miss Teen USA and related content. The deal valuations were not disclosed and Endeavor considered it a strategic fit to its portfolio.
Trump was a presidential candidate when the deal was struck. He had owned the pageant for nearly two decades during which he courted multiple controversies for his sexist remarks. For instance, in 2019, he infamously boasted to talk show host David Letterman about his approach to the pageants, saying, "I made the heels higher and the bathing suits smaller.
A Fighting Chance
Think UFC and think of Irelands larger than life Notorious Conor McGregor and his Proper 12 whiskey brand, Brazilian legend Anderson Silva, former ladies champion Rowdy Ronda Rousey, who switched to the WWE (World Wrestling Entertainment) and the humble Russian Khabib Nurmagomedov, who wrestled with bear cubs during his childhood. In 2016, in the most expensive transaction in sports history, UFC was sold to Endeavor for $4 billion.
The UFC showcases real combat competition, unlike the WWE, which follows a scripted format. The firm is one of the largest Pay-Per-View event providers in the world, and its content is broadcast in over 156 countries and territories to more than 1.1 billion television households worldwide. Ari Emanuel and team are betting big on the UFC as live audiences come back to arenas and online views of fights surge in markets like China.
Endeavors Back Home
Some of the desi peers of Endeavor in the event and celebrity management segments include the likes of Wizcraft, Cineyug, Fountainhead, OML, Matrix, KWAN (now Collective Artists Network) and Bling. Additionally, the likes of Zee Live, which focus on onground experiences for audiences, have rolled out a countrywide theatre tour.
Experts tracking the domestic entertainment sector believe that the segment is disproportionately dominated by TV and cinema in terms of revenues. But as spending increases, these industry observers are confident that leisure expenditure in niche segments like live sports will grow at a rapid pace. Scalability may be a challenge and investors may play ball only if businesses reach the desired size, but the growth potential is high, they feel.
Here is the original post:
Posted in Elon Musk
Comments Off on The firm that connects Elon Musk, Rihanna, mixed martial arts and three Reliance Jio investors – Moneycontrol
Opinion | Why Virgin Galactic Couldn’t Beat Elon Musk to Space – The New York Times
Posted: at 8:09 pm
Yet Virgin Galactic forges ahead. It plans to resume its rocket-powered flight test program in May, and its new chief executive, Michael Colglazier, the former head of Disneys international theme park division, appears intent on dealing with past difficulties. It recently unveiled a spaceship that includes metallic fasteners that help prevent disbonding, and a stability augmentation system that automates an aspect of the flight and allows for a smoother ride.
While these changes could address some of Virgin Galactics problems, its DNA as a rocket plane company remains the same a DNA that may present its greatest challenge, according to Luke Colby, a propulsion engineer who worked on Virgin Galactics spaceship program for nearly a decade and has also consulted for SpaceX and Blue Origin. If you want a space vehicle to be fully reusable for airline-like traffic, it doesnt have to look like an airplane, Mr. Colby said. It just has to function like one. And the physics really drive you toward a two-stage, vertical-take-off-and-vertical-landing rocket.
He accepted that Virgin Galactic is likely to be remembered as one of the first but not necessarily the most successful of the first new space companies a sobering admission. Its problem, he said, was that the company was driven by nostalgia for aeronautical flight. Blue Origin and SpaceX, on the other hand? They have been driven by the physics of spaceflight, he said.
Physics presented one challenge; human nature posed another. Put simply, Virgin Galactic has set a standard of perfection for itself that is noble but nave. As one test pilot said, Ninety-nine percent isnt good enough. An accident rate of less than 1 percent on an experimental rocket ship? Near impossible. Those are the hard realities of romance.
Perhaps thats what made this company so fascinating to watch: its hope, in spite of the odds. I wanted to see it succeed not because I cared who won the private space race but because I admired the passion and optimism shared by the techs and engineers and test pilots on the project. We can only hope when we fear failure, and that was one thing algorithms couldnt yet do: hope. The human factor had worked its magic on me.
My kids felt it, too. They still talk about watching that ship blast off and then later standing at the foot of the stage while Beth Moses, elated at what shed just witnessed, struggled to find the words to articulate her experience, while her husband and her own children gazed up at her in awe.
That, she said, is an indescribable ride.
Visit link:
Opinion | Why Virgin Galactic Couldn't Beat Elon Musk to Space - The New York Times
Posted in Elon Musk
Comments Off on Opinion | Why Virgin Galactic Couldn’t Beat Elon Musk to Space – The New York Times
SNL Cast Members Can Skip the Elon Musk Show If They Really Hate Him Being There – autoevolution
Posted: at 8:09 pm
On May 8, 2021, Technoking and Imperator of Mars Elon Musk will be making his comedy debut, hosting Saturday Night Live on NBC. Confirmation of his hosting is still getting many people very hot under the collar.
Even SNL cast members voiced their displeasure at having Musk on the show, one way or the other. Among them, Bowen Yang, Aidy Bryant, Michael Che, and writer Andrew Dismukes posted messages on social media, showing or hinting that they thought the host choice was a very bad one.
According to Page Six, if any one of these SNL regulars or others find the job of sharing the screen with Musk too much to bear, they can simply opt out of this weeks episode. Speaking historically, if a cast member has been that unhappy, they dont have to do it, a source tells the publication. [SNL boss Lorne Michaels] wont ever make them do anything they dont want to do. The same source says that Musk is very much a showman, which is probably a comeback to all those claiming Michaels and NBC sold out for bigger ratings. After all, SNL is hardly in the habit of bringing tech guys or public figures that are too controversial on board.
On a positive note, the report notes that not one of the SNL regulars has yet announced an intention to skip this weeks show. Good or bad, Musks appearance on the show will be history in the making. And, certainly, the ratings are bound to go up, especially since Mr. Technoking has made it clear that he has no plan of toning it down for the sake of the cameras.
Follow this link:
SNL Cast Members Can Skip the Elon Musk Show If They Really Hate Him Being There - autoevolution
Posted in Elon Musk
Comments Off on SNL Cast Members Can Skip the Elon Musk Show If They Really Hate Him Being There – autoevolution
The Surprising Reason Scientists Haven’t Been Able to Clone a Bird Yet – National Audubon Society
Posted: at 8:09 pm
One current project aims to use new technology to create domestic chickens with the gonads of Greater Prairie-Chickens, giving the barnyard birds the ability to produce prairie-chicken eggs. Photo: Ravi Hirekatur/Audubon Photography Awards
Earlier this year, scientists announced that they had successfully cloned an endangered North American species for the first time. Elizabeth Ann the black-footed ferretthe clone of an individual named Willa who died more than30 years agowas born via C-section on December 10, 2020. Without the aid of cloning technology or the forward-thinking researchers who froze Willas DNA, her genes would have been lost forever. Elizabeth Anns birth bringsfresh genetic diversity to the black-footed ferret captive-breeding program, and is an important step towardhelping other endangered species.
Conservation cloning is a tool of last resort. Its most promisinguses are either for species that are descended from just a handful of individuals,known as a genetic bottleneck,or species that are in danger of going extinct now. Even though Elizabeth Ann's birth demonstrates cloning's potential hope for at-risk mammals, its a different story when it comes to avian conservation.
Weve been asked a few times now, when is this going to happen for birds?, says Ben Novak, a lead scientist with Revive & Restore, the organization that spearheaded the black-footed ferret cloning efforts. The answer, Novak says, is probably nevercloning likely isnt possible in birds.
To understand why, its important to know how cloning works. Theres more than one way to get a clone (including, for instance, identical twins), but the technique made famous by Dolly the sheep and used to create Elizabeth Ann is called somatic cell nuclear transfer.This process involves swapping out the genetic information of an egg cell and replacing it with the DNA of a donor individual. First, the researchers take the egg cell and place it under a microscope. Then, they zero in on its nucleus, which is the part of the cell that contains the vast majority of its genetic information. They carefully suck that nucleus out, leaving the egg cell empty of its genetic code. This means that the egg is now a blank slate ready to be filled with a new set of instructions.
The next step is to insert either a body cell (also known as a somatic cell) or its nucleus from the individual they want to clone, which contains the donors genetic material. Once the new cell and itsinstructions are inside the egg, researchers encourage the two to fuse with a jolt of electricity. If everything has gone right, this tricks the egg cell into thinking it has been fertilized, and it will start to divide and multiply, forming an embryo.After growing for a while in a petri dish, theresulting embryo can be implanted in the uterus of a surrogate mother, who will give birth to a clone.
In practice, only a fraction of these nuclear transfers result in viable embryos that go on to become adult animals. Even so, a lot of mammalseven wild species like deer, graywolves, and macaqueshave been cloned in this way since Dolly the sheep proved it was possible back in 1996. But there has never been a single cloned bird.
There are a few reasons why birds have been impossible to clone so far.The biggest hurdle? Its what you had for breakfast, says Tom Jensen, a reproductive scientist with the San Diego Zoo Wildlife Alliance. The egg yolk.
That nucleus-swapping trick is easy enough to do with mammal egg cells, which range from about one to three human hairs width in diameter, Jensen explains. These little eggs are the perfect size to slide under a microscope, where scientists can get down to a microscopic level and locate the tiny DNA-containing nucleus. But in birds, the egg cellwhat we call the yolkis a lot bigger. And the nucleus holding all of the bird's DNA is a miniscule white dot in the middle of that yolk, which the embryo will eventually grow out of.
The yolk is basically a bird embryo'spacked lunch from mom, providing it with all thenutrients itneeds toeventually growintoa baby bird ready to hatch.The arrangement is anefficient one, but it alsopresents two majorissuesfor scientists trying toclone a bird. First, the yolk's sizeprevents it fromfittingunder amicroscope to conduct the necessary work. And second, even if scientists could inspect the yolk on a microscopic level,findingthat tinynucleus floating somewhere in the yolkisextremely challenging. Novak hasdescribedthe process as akin to "looking for a white marble in a pool of milk."
Another issue with eggsis that once the yolk leaves the ovary, it is always on the move. During the typical cloning process with a mammal, researchers can just stick the embryo in a surrogate mothers uterus and let it grow. Birds have no such incubation chamber. After the yolk forms, its dropped into something called the oviduct, where it tumbles down an assembly line that coats it with first the egg white, and then the shell membrane. There is no uterus equivalent in which to stick a bird clone embryo.
Its technically much easier in a mammal than it would be in a bird, Jensen says. So, I dont think itll ever be anything we can use for bird conservation.
Currently, without the ability to cryopreserve the cells ofbird species and clone themlater, there is no scientific failsafe for birds like there is for mammalsin case of genetic bottlenecks orcritical endangerment.However,Jensen is hoping a different emerging genetic technology could perform a similar role for endangered bird species. This onefocuses not on creating an entire clone, but on altering what kinds of chicks an individual is producing. That requires researchers to focus on birds' testes and ovaries, also called the gonads.We dont really care that [the host species]looks like the animal, what we care about is that its gonads are identical to the animal that were cloning, right? Jensen says. In birds, we can kind of clone the gonad.
The bird answer to cloning hinges on something called primordial germ cells, or PGCs. Thats basically a fancy term for the cells that are destined to become sperm and egg cells. Cloning a mammal involves inserting the DNA of one individual into one egg, and producing one offspring that is the genetic replica of the donor. With PGC technology, the goal is to createa surrogate with gonads that contain the DNA of another species. Reseearchers refer to these hybrid animalsas chimeras.
To makea chimera, researchers carefully insert PGCs from a donor into a host embryo as it is developing. The PGCs then migrate down to the host embryos gonads. If everything goes to plan, the host will grow up to become an adultthat produces sperm or eggs containing the DNA of the donor.
So, for instance, you might have a domestic rooster host who produces sperm with the DNA of a Greater Prairie-Chicken. If the rooster were mated with a female Greater Prairie-Chicken, the pair could then produce Greater Prairie-Chicken chicks. This approach has the benefit that one host parent could theoretically produce many offspring with the DNA of a donor over the course of its lifetime, rather than the single individual that would be produced via cloning. And, as long as researchers can cryopreserve these PGCs, this can still offer the benefit of bringing back DNA from a donor that died long ago.
The catch is that PGC technology is much trickier than cloning, with more steps that could potentially go wrong, so its still in development.Researchers have made some progress, however, that makes Jensen and Novak hopeful that the technology could one day be used for conservation.
Most of the research thus far has involved domestic chickens. Several groups of researchers have successfully transferred PGCs from one breed of chicken into another, producing offspring with donor DNA. Researchers have also used the technique to successfully produce Maya Ducks, Korean Pheasants, and even Houbara Bustards by mating chimera domestic chicken males to the females of those species.
Jensen and his team, for their part, are looking into whether stem cells from dead individuals can be used for this technique, and trying to figure out how far apart the donor and the host species can be genetically. So far, any cells his lab has experimentally introduced to chicken embryos have migrated to the gonads like theyre supposed to. Which is a really, really good sign for working across multiple specieseven distantly related species, Jensen says. Although we have not yet hatched any chickens to verify functional sperm production.
Revive & Restore, meanwhile, is in the process of producing interspecies chimeraswithconservation in mind. More specifically, theyre in the preliminary stages of gettingdomestic chickens to produce Greater Prairie-Chicken sperm. Rosemary Walzem, a researcher with Texas A&M University, is currently leading these efforts. Her labhosts a flock of Greater Prairie-Chickens, and this spring her team is hoping to carefully extract some primordial germ cells (a tricky task in its own right) to eventually try to introduce into domestic chickens. The idea is to perfect the process with a species that is closely related to domestic chickens, then apply what they learn to related species that are endangeredor even extinct.
Eventually, this technology might help to improve the genetic diversity of species like California Condors or Whooping Cranes that are descended from just a few individuals. Pretty much any breeding program where you could go in and bring an individual back from decades later would really benefit from that diversity injection, Jensen says.
Ideally, this technology would never be necessary. The best approach to conservation is to keep species plentiful and their habitats and ecosystems intact. But it could be a valuable tool in worst-case scenarios. Jensen and Novak say that they ultimately hope the technology will be developed to the point that researchers can capture wild birds with mist nets, extracttheir primordial germ cells, and then release them. The cells could then be stored away, or they could immediately be placed in a host to reproduce more of the species without having to take a wild population into captive breeding. But that vision is still a long way off, both admit.Our goals are very ambitious, Novak says. But we think theyre doable.
More:
The Surprising Reason Scientists Haven't Been Able to Clone a Bird Yet - National Audubon Society
Posted in Cloning
Comments Off on The Surprising Reason Scientists Haven’t Been Able to Clone a Bird Yet – National Audubon Society
JPJ finds there are vehicle owners who conspired with car cloning syndicates to duplicate original road tax – paultan.org – Paul Tan’s Automotive News
Posted: at 8:09 pm
The Road Transport Department (JPJ) has said that the act of falsifying the registration of cars smuggled into Malaysia, commonly referred to as cloned cars, is not only done secretly without the knowledge of the original owners, but also by those who conspired with syndicates that offered them compensation to be involved in the illegal act.
In a report by Sinar Harian, the director of JPJ Selangor, Nazli Md Taib, said that low prices spur the demand for cloned cars mostly luxury vehicles and that from 2016 to March this year, a total of 314 cloned vehicles have been seized.
A cloned vehicle is defined as any motor vehicle used on the road that resembles a Malaysian-registered vehicle, using identical number plates taken from a similar legitimately-registered model. According to Nazli, there are a few categories of cloned vehicles, including those that are not registered and brought in through ports or borders either from Thailand or Singapore.
For example, in the case of a cloned Toyota Vellfire in white, the syndicate will clone the vehicle using an existing Toyota Vellfire [of the same colour] registered in the country. The cloned vehicle would then be used in Kedah or states where it is unlikely that the owner of the legitimately registered vehicle will go to the states involved to avoid it being detected, said Nazli.
This cloned car will use either a falsified road tax or a copy of the original vehicle road tax. If the syndicate takes someone elses registration number and uses it on a cloned car, this is a forgery. Most cases like these are brought up to us when the original owner says he received a summon in a place he never went to. As such, we will send the information to the state concerned for further action, he continued.
While this category of cloned cars involves falsifying a vehicle registration without the knowledge of the original owner, Nazli said there are those who conspired with syndicates to perform the illegal act. As an example, he said there was a case where a syndicate approached a Volkswagen owner and offered to pay his monthly car instalment in exchange for duplicating the vehicles registration.
The owner, influenced by money, would agree to the terms. This is a case of the owner agreeing. The suspect would then clone several of such cars based on the agreement between the owner and the syndicate, Nazli explained.
The syndicate would then bring in the cloned car using the same registration number as the original car. The syndicate and the original vehicle owner would also agree on certain terms, including forbidding the latter to go to the state where the cloned car was sold in, he added.
Nazli goes on to say that based on the agreement with by the syndicate, the original vehicle owner will go to the department to apply for a new road tax disc on the pretense of the current one being damaged or missing. Here, the original vehicle owner that conspired with the syndicate will obtain a new road tax disc and hand it over to the syndicate to be used on the cloned car, he said.
Nazli noted that cloned vehicles that are registered this way were worth more than those with fake registrations, adding that syndicates were also able to use advanced technologies to produce fake road tax discs that appeared genuine.
The department picked up on this activity when the original vehicle owner came to apply for a new road tax again for the third time using the same excuses. There have also been cases where a syndicate revived the registration of vehicles that have been declared a total lost after being involved in a serious accident.
These acts make it difficult for the public to determine if a car has been registered legally or cloned, Nazli commented, adding that it can be very difficult to differentiate a forged road tax disc from an original, requiring the department to send samples to Percetakan Nasional for validation. He goes on to say that if a luxury vehicle is sold for as low as RM20,000, theres certainly something amiss with the vehicle, but there are still those who buy it.
Link:
Posted in Cloning
Comments Off on JPJ finds there are vehicle owners who conspired with car cloning syndicates to duplicate original road tax – paultan.org – Paul Tan’s Automotive News
Pose Recap: Im Not Trying to Be Nice – Vulture
Posted: at 8:08 pm
Pose
Intervention
Season 3 Episode 2
Editors Rating 3 stars ***
Photo: Eric Liebowitz/FX
The title for the second episode of Poses final season (which aired in tandem with its premiere opener) hints at exactly what dominates the hour-long proceedings. Only, it would have perhaps been more accurate had the title been a plural. Intervention may hint at the staged gathering wherein Blanca (Mj Rodriguez) and the House of Evangelista lovingly attempt to get Pray Tell (Billy Porter) to acknowledge the fact that he has a drinking problem, but there were several scenes peppered throughout that followed that very same dynamic (see: Papi and Angel, Elektra and Lulu).
But the bluntness of the episodes title speaks also to the tacitly understood structure of the show. Theres always been a welcome didacticism to Pose, an understanding that the FX drama hopes to be this generations Beverly Hills, 90210. Or, rather, its contemporary companion. Seen side by side, especially when operating in the kind of very special episode vein that an entry like Intervention so recalls, 90210 and Pose almost feel like sister shows, intent on serving as narrative PSAs that embolden viewers young and old to understand why some people make the ill-conceived choices they make. Pose is both a belated corrective and a fabulous reworking of that kind of storytelling, filtered through the specificity of its queer and trans characters, many of whom (like Pray) carry with them traumas and burdens that span generations.
So yes, if there are some moments in the episode that feel a tad ham-fisted or slightly overwrought, Im inclined to look past them. Its not just that I couldnt have fathomed seeing the kinds of conversations about addiction as tied to the grief over HIV/AIDS on a show like 90210 back when I was a teen, but that now, in my 30s, seeing those same conversations feels powerful in and of itself: Much is made of what a show like Pose is doing for younger generations, but Im constantly reminded (especially in those moments where intergenerational rivalries and solidarities flare up, as between Pray and Lemar, or Pray and Ricky) that this chronicle of a queer past is a potent call to arms for our very present.
Watching Blanca, for instance, navigating a terse outing with Christophers parents filled with euphemistic barbs (his mother finds the prospect of Blancas having owned a nail salon stimulating and her growing up in the projects colorful) only to then see her standing up for herself is as heartwarming as it is empowering. She may claim shes lost her self-confidence, but theres something in Blanca that will always make her stand out and stand up for herself. Credit where its due: Rodriguezs ability to capture a fragile but steely resilience is what makes Blanca such a revelation; watch her in those two meet the Huxtables scenes and notice how shes constantly shuttling between shrinking herself to be liked and gritting her teeth for making herself do so. By the time she stands up (quite literally), it feels like a vision of the Blanca we know, the one Christopher first fell in love with. Its a glorious moment of self-empowerment that is accompanied by a loving show of support: The dinners been a redo and Christopher has risen to the challenge when, perhaps in a different show, he may have failed.
I return here, as I did in my previous recap, to the way this signals a subtle but undeniable aspect of the writing in Pose: These are people who are not only rooting for their characters, but actively creating worlds (as imagined as they are authentic) that allow them to be the selves they deserve to be. Thats why even when the show puts a character like Pray Tell in a situation where hes clearly on the path to self-destruction, you know therell be a light at the end of the tunnel. Does this deprive the show of what we would normally call narrative tension because we trust a happy ending will be inevitable? Perhaps. But as Pray in this episode shows, that doesnt detract from Pose extracting all the drama out of such a plotline.
Which is to say: This episode alone could handily win Billy Porter another Emmy.
Think about it: In the span of an hour, we get to see the actor perform a killer lip sync (give it up for En Vogue!), deliver a scathing series of all too personal reads (If I wanted advice from a crackhead, I would walk out on the streets and ask for it), break down in tears when faced with the prospect of losing Ricky, and finally find his way back to sobriety before checking into rehab upstate. Porter gives you everything: the numbness that comes with alcoholism, the euphoria that comes with an energetic ballroom outing, the righteous frustration that comes with seeing friends and former lovers dying all while showing the children what a seasoned performer can do with a perfectly timed close-up.
Again, Prays storytelling feels all too neatly parceled out, too tidy even amidst Poses penchant for keeping its episodes tightly packaged. I mean, the episode is titled Intervention; obviously this wasnt designed as a season-long arc despite its rich thematic content. But even with this accelerated pacing, theres no denying Porter was given a feast of an episode (give or take a too-clever clunky line like, I drink because I hate myself. And I hate myself because I drink).
And just as with Blancas story line (funny how both of these early episodes have so sidelined the shows ancillary characters, no?), Prays moments of self-reflection hit a chord precisely because they vocalize what many then (and perhaps to this day) carry with them as they cope with life in the shadow of HIV/AIDS. What do you do with such pain? What do you do with the trauma? How do you go on with your life when your every day is shaded by death? The House of Evangelista is right to call Pray out on his drinking, but they dont really have too many answers as to how better to go on when his body, his life, his friends are constant reminders of what seems like an inevitable outcome.
Thats what made his outburst during his intervention so painful. Whether calling out Elektra for her delusions of grandeur or sniping at Papi for riding Angels coattails, you got to see Pray wielding his sharp tongue on his loved ones with the same verve he no doubt reserves for himself. There was no generosity there, just the lashing out of someone in pain taking the blade hes been using on himself to hurt everyone around him. That his reads also echoed his stage presence and his role as emcee merely stressed how his acid-tongued performances always hid a darker way of looking at the world. But where amid the glitter of the balls, hed turned that skill into a shining moment of levity, here it was swallowed whole by the darkness that so consumes him.
Itll be interesting to see what a post-rehab and sober Pray looks like, both in and out of the spotlight. Lets just hope it gives Porter even more fabulous notes to play as he sketches out the final few episodes of one of televisions most fascinating characters.
Who are you calling queer? I am a proud transexual woman! I loved Lulus almost throwaway line during the intervention prep: It was a quick gloss on the way umbrella labels like queer can oftentimes obscure the specific lived-in experiences of those theyre trying to include.
Im still gagging over Elektras feathered ensemble. And Prays glittery romper.
I know the show has long framed Blanca as the central mother figure (she was called out as such by Pray himself in this episode), but can we take a moment to rejoice in Ms. Elektras excellent mothering skills? She may never get herself a Piet-like statue, but her no-bullshit, tough-love approach (with Lulu: The category is: seamstress!, with Blanca: You are every-fucking-thing!, and even with Pray: Think of your skin-care routine if nothing else!) remains especially welcome, especially during scenes when the shows writing risks becoming all too cloying.
Any show that manages to feature Toni Braxton, En Vogue, Janet Jackson, and Mariah Carey in a single episode deserves extra props.
Keep up with all the drama of your favorite shows!
Here is the original post:
Posted in Personal Empowerment
Comments Off on Pose Recap: Im Not Trying to Be Nice – Vulture







