Daily Archives: May 7, 2021

WANTED PHOTO: DNA leads to the identity of a suspect on the run, in a burglary of a home – CW39

Posted: May 7, 2021 at 4:08 am

HOUSTON (CW39) Deputies credit a DNA match, with identifying a suspect, wanted in the burglary of a home. Back in December of 2019, deputies with Harris County Precinct 4, responded to a burglary at a home, in the 14100 block of Cypress in North Houston. While on scene, deputies collected a DNA sample from the burglarized residence. The evidence was sent to the Harris County Institute of Forensic Science for testing.

In May 2021, Constable Investigators received a DNA match that linked suspect- Michael Washington to the burglary. Right now, he is no where to be found. Thats why the Constables office is calling on residents help find Mr. Washington.

Michael Washington is currently wanted by law enforcement for Burglary of a Habitation as well as an unrelated Aggravated Robbery with a Deadly Weapon case. He received No Bond out of the 177th District Court. If you have any information regarding his whereabouts, you are urged to contact our dispatch or your local law enforcement.

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Hot Spots of Aging and Disease Revealed by How Brain Cells Repair Their DNA – SciTechDaily

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Salk scientists reveal new insights into neurodegenerative disorders and potential for genetic therapies.

Neurons lack the ability to replicate their DNA, so theyre constantly working to repair damage to their genome. Now, a new study by Salk scientists finds that these repairs are not random, but instead focus on protecting certain genetic hot spots that appear to play a critical role in neural identity and function.

The findings, published in the April 2, 2021, issue of Science, give novel insights into the genetic structures involved in aging and neurodegeneration, and could point to the development of potential new therapies for diseases such Alzheimers, Parkinsons and other age-related dementia disorders.

In this image of a neuron nucleus, bright spots show areas of focused genetic repair. Credit: Salk Institute/Waitt Advanced Biophotonics Center

This research shows for the first time that there are sections of genome that neurons prioritize when it comes to repair, says Professor and Salk President Rusty Gage, the papers co-corresponding author. Were excited about the potential of these findings to change the way we view many age-related diseases of the nervous system and potentially explore DNA repair as a therapeutic approach.

Unlike other cells, neurons generally dont replace themselves over time, making them among the longest-living cells in the human body. Their longevity makes it even more important that they repair lesions in their DNA as they age, in order to maintain their function over the decades of a human life span. As they get older, neurons ability to make these genetic repairs declines, which could explain why people develop age-related neurodegenerative diseases like Alzheimers and Parkinsons.

To investigate how neurons maintain genome health, the study authors developed a new technique they term Repair-seq. The team produced neurons from stem cells and fed them synthetic nucleosidesmolecules that serve as building blocks for DNA. These artificial nucleosides could be found via DNA sequencing and imaged, showing where the neurons used them to make repairs to DNA that was damaged by normal cellular processes. While the scientists expected to see some prioritization, they were surprised by just how focused the neurons were on protecting certain sections of the genome.

What we saw was incredibly sharp, well-defined regions of repair; very focused areas that were substantially higher than background levels, says co-first and co-corresponding author Dylan Reid, a former Salk postdoctoral scholar and now a fellow at Vertex Pharmaceutics. The proteins that sit on these hot spots are implicated in neurodegenerative disease, and the sites are also linked to aging.

The authors found approximately 65,000 hot spots that covered around 2 percent of the neuronal genome. They then used proteomics approaches to detect what proteins were found at these hot spots, implicating many splicing-related proteins. (These are involved in the eventual production of other proteins.) Many of these sites appeared to be quite stable when the cells were treated with DNA-damaging agents, and the most stable DNA repair hot spots were found to be strongly associated with sites where chemical tags attach (methylation) that are best at predicting neuronal age.

From left: Rusty Gage and Dylan Reid. Credit: Salk Institute, Dylan Reid

Previous research has focused on identifying the sections of DNA that suffer genetic damage, but this is the first time researchers have looked for where the genome is being heavily repaired.

We flipped the paradigm from looking for damage to looking for repair, and thats why we were able to find these hot spots, Reid says. This is really new biology that might eventually change how we understand neurons in the nervous system, and the more we understand that, the more we can look to develop therapies addressing age-related diseases.

Gage, who holds the Vi and John Adler Chair for Research on Age-Related Neurodegenerative Disease, adds, Understanding which areas within the genome are vulnerable to damage is a very exciting topic for our lab. We think Repair-seq will be a powerful tool for research, and we continue to explore additional new methods to study genome integrity, particularly in relation to aging and disease.

Reference: Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons by Dylan A. Reid, Patrick J. Reed, Johannes C. M. Schlachetzki, Ioana I. Nitulescu, Grace Chou, Enoch C. Tsui, Jeffrey R. Jones, Sahaana Chandran, Ake T. Lu, Claire A. McClain, Jean H. Ooi, Tzu-Wen Wang, Addison J. Lana, Sara B. Linker, Anthony S. Ricciardulli, Shong Lau, Simon T. Schafer, Steve Horvath, Jesse R. Dixon, Nasun Hah, Christopher K. Glass and Fred H. Gage, 2 April 2021, Science.DOI: 10.1126/science.abb9032

Other authors on the study are Patrick Reed, Ioana Nitulescu, Enoch Tsui, Jeffrey Jones, Claire McClain, Simon Schafer, Grace Chou, Tzu-Wen Wang, Nasun Hah, Sahaana Chandran and Jesse Dixon of Salk; Johannes Schlachetzki, Addison Lana, and Christopher Glass of the University of California, San Diego; Ake Lu and Steve Horvath of the University of California, Los Angeles.

The research was supported by the American Heart Association, the Paul G. Allen Frontiers Group, the JPB Foundation, the Dolby Foundation, the Helmsley Charitable Trust, and the National Institutes of Health.

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New DNA information emerges in Ledell Lee case, 4 years after execution – Arkansas Online

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Four years after the execution of an inmate convicted of murdering his Jacksonville neighbor in 1993, new DNA evidence has emerged revealing genetic material and fingerprints from an unknown male, according to a report released Friday from the Innocence Project and the American Civil Liberties Union.

Ledell Lee maintained his innocence until he was executed on April 20, 2017, for the murder of Debra Reese. Lee was convicted in 1995.

DNA testing of evidence from the crime scene, including the murder weapon and a bloody shirt, revealed the profile of an unknown male. New fingerprints found on crime scene evidence could also not be identified, according to the Innocence Project and the ACLU.

The DNA and fingerprint profiles have been entered into a national database but so far no matches have been identified.

While the results obtained 29 years after the evidence was collected proved to be incomplete and partial, it is notable that there are now new DNA profiles that were not available during the trial and post-conviction proceedings in Mr. Lees case, Nina Morrison, Innocence Project senior litigation counsel, said in a statement.

We are hopeful that one or more of these forensic law enforcement databases will generate additional information in the future, Morrison said.

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New DNA information emerges in Ledell Lee case, 4 years after execution - Arkansas Online

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DNA and the Death Penalty: Why Ledell Lees Case Should Increase Calls for Abolishment – EBONY

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If our criminal justice system is to pull from the brink of insanity, it should be designed not just to punish, but to rehabilitate without foreclosing that opportunity.

The death penalty kills innocent people.

This is what reads upon the hoodie and T-shirt from the Forgive Everyone Collective, an abolitionist screen printing collective from Grand Rapids, Michigan. On it, the names of 173 individuals who were sentenced to death and later exonerated are featured on the item, and Ledell Lee might have been another to addbut he was executed for murder in a flurry of lethal injections despite lawyers calls for DNA testing.

No one should be executed when there is a possibility that that person is innocent, attorney Nina Morrison said in April 2017, just after Leeconvicted in the 1990sbecame the first person put to death in Arkansas in more than a decade. This week, four years later, attorneys shared word that genetic material from the murder weapon in Lees case pointed to someone else. On the handle of the bloody club apparently used to bludgeon Debra Reese to death, new testing found DNA from an unknown man, in an effort led by The Innocence Project, the American Civil Liberties Union and Lees family to exonerate him even after his execution.

25 states, including, Kansas, Indiana, Virginia and Texas still have the death penalty, according to a 2020 study. Four others, Colorado, Pennsylvania, California, and Oregon have suspended the law until deemed worthy again. And even despite what may be looked at like diminished usage, the flaws and failures of capital punishment are more apparent than ever before. In a study released in October 2015, 156 individuals have been exonerated from death row, which means for every 10 people who have been sentenced to death, only one person has been set free. As Arkansas Gov. Asa Hutchinson tells it, even if the new evidence were to have been submitted before Ledell Lees execution date, he wouldve ignored the chance of examining the discovery and called for his death. They [the Supreme Court] affirmed the convictions and its my duty to carry out the law, Hutchinson said, reacting during Wednesdays news briefing. The evidence obviously thats been uncovered is inconclusive and the fact is that the jury found him guilty based upon the information that they had.

Guilty.

It is uniquely interesting how that word can subscribe a man to death in a Christian country that professes to expound values found in the Ten Commandments. While many outside a certain demographic know this to be untrue, you would think that those Boastful Bible Thumpers would realize the hypocrisy in their behavior. In the King James version of the Holy Scriptures, the argument is made that thou shalt not kill should be interpreted as thou shalt not murder, which when placed against how many innocent lives the American death penalty has taken, that this act of justice would be deemed an affront against God.

According to the Criminal Justice Project of the NAACP, there are 2,620 people on death row in the US as of Jan. 1, 2020.

This includes Mumia Abu Jamal, a political activist and journalist who was sentenced to death in 1982 for the murder of a Philadelphia police officer, but whos sentence was overturned by a Federal court in 2011.

And since 1976, when the death penalty was reinstated by the US Supreme Court, states with the legal authority to do so have executed 1,516 people (as of July 2020).

How does ending ones lifeespecially an innocent or potentially innocent onemake one accountable for their actions? The Forgive Everyone Collective defines accountability as understanding ones harm, choosing transformation, and committing to systemic change. Ledell Lees family, equipped with evidence that counters the claim, even after his execution, points out just how important it is to abolish the death penalty. According to The Innocence Project, eighteen people have been proven innocent and exonerated by DNA testing in the United States after serving time on death row. Think about how those people served a combine 229 years in prisonincluding 202 years on death rowfor crimes they didnt commit, and then think of them being denied because new evidence is inconclusive or the jury found them guilty based upon the information that they had.

And then open your eyes and see Ledell Lee.

While his innocence or guilt can no longer be argued, what can is that the death penalty has again come under spotlight for all the wrong reasons. It is state-sanctioned revenge that does not achieve accountability, healing or transformationand it definitely does not improve public or personal safety.

Were all more than the worst thing weve ever done, because were all capable of change and growth. The death penalty affects and traumatizes everyone it touches. If our criminal justice system is to pull from the brink of insanity, it should be designed not just to punish, but to rehabilitate and offer transformation, redemption and gracewithout foreclosing that opportunity.

Joane Amay is the Beauty and Style Director at Ebony magazine. A hoarder of shoes, baubles and sparkly things, she dreams one day of owning her own private island.

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DNA Testing To Be Done In Nationally Known ‘Fatal Attraction’ Case In Westchester – Peekskill Daily Voice

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Westchester County prosecutors have given the green light for DNA testing on evidence linked to the 1992 conviction of Carolyn Warmus in the Fatal Attraction killing of her lovers wife.

Two years ago, Warmus, a former school teacher in Westchester, was granted parole following her conviction for her alleged role in the famed 1989 fatal shooting of Greenburgh resident Betty Jeanne Solomon, the wife of Warmus' lover, Paul Solomon, nine times in the back.

Warmus was sentenced to a term of 25 years to life in prison.

Warmus and Solomon had met when they both were teaching at the Greenville Elementary School in Edgemont. At the time of the fatal incident, Warmus, the daughter of a millionaire insurance executive, was 27, while her victim was 40.

Since being imprisoned, Warmus has vehemently maintained her innocence, and sought to have several pieces of evidence tested to determine if they can exonerate her and identify a new suspect.

This week, Westchester County District Attorney Mimi Rocahs office agreed to perform DNA testing on that evidence, which includes a glove and bag found near Solomons body, that contributed to Warmus' conviction.

According to Warmus attorneys, the DNA testing could represent a significant development in clearing her name. Both they and the prosecution are set to meet at a later date to determine how testing will proceed.

"However, because a prior DA's administration initially consented to DNA testing, and because we have only just established this office's first-ever independent Conviction Review Bureau and developed the bureaus intake protocols, we will make an exception and consent to the requested DNA testing in this specific case," a spokesperson for Rocah stated.

The murder garnered national attention and happened two years after the release of the blockbuster movie Fatal Attraction, in which longtime Westchester resident Glenn Close, who lived in Bedford, starred as a book editor who had an affair with a happily married man, played by Michael Douglas.

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Taylor Richardson is reaching for the stars – The Resident Community News Group, Inc. – The Resident Community News

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Posted on May 6, 2021By EditorJunior Residents

Taylor Richardson | Photo Credit: Renee Parenteau

At only 17 years old, Taylor Richardson has already impacted the local community, the country, the world. She aspires to someday impact space.

Taylor is determined to visit Mars. A little Black girl walking around in an astronauts suit saying she wants to go to Mars was a very lofty dream. But she is doing the work to try to ensure that, said her mother, Latonja Richardson.

Taylors service and advocacy work began when she was 9 years old when she built a Mars colony, a project that earned her a stay at Alabamas Space Camp where she was the only Black girl of 500 attending. There, she was given the nickname Astronaut StarBright.

Most people know her for her philanthropy skills. In the last three years, Taylor has raised almost $250,000 for girls empowerment and STEM resources for girls, particularly girls of color, not just nationally, but internationally as well, said Latonja.

Through my work, the legacy I want to leave behind is to bring a sisterhood of warriors with me all the way to the stars by disrupting the status quo where Black girls like me have equal representation at the table, Taylor said. And her intention is not only to benefit Black girls, but all girls.

Taylor launched The Black Friend Challenge, hoping to distribute 100 copies of the book The Black Friend by Frederick Joseph as a way to prompt dialogue to combat racism. So far, shes raised over $22,000, and all 21 Jacksonville public libraries now have the book available, as do over 30 states and 40 US Embassies.

In June 2019, Taylor was the first Black girl and the youngest ever to receive an Aspiring EVE award by The Florida Times-Union. Though she is still too young to vote, in summer 2019, Taylor helped 150 Jacksonville youth register to vote. She has been interviewed on national news shows along with celebrities like Oprah Winfrey and Mae Jemison, the first African American woman to travel through space.

Taylor has spoken at conferences around the world to push #RepresentationMatters. She has graced the covers of two scholastic science magazines. She was voted 2017 Girl of the Year for Women in Aviation, being the first African American girl to do so. She is featured in two documentary films that are doing well in festivals across the country. She has her own Wikipedia page, and a list of other accomplishments too lengthy to print.

As a young child, Taylor was bullied due to the color of her skin and to her diagnosis of ADHD (Attention Deficit Hyperactivity Disorder). She changed the acronym to Abundantly Different Happily Divine, trademarked that name, and now sells ADHD apparel. The proceeds she donates to a local ADHD foundation and to space initiatives.

Taylor has proven that labels of any sort need not hold anyone back from following their dreams and achieving their goals. What Im most proud about with Taylor is not her successes but how she has handled her failures, how she has handled being bullied, said Latonja.

Despite her early setbacks, Taylor is currently a junior at The Bolles School, maintaining a 3.8 GPA while attending virtual classes. Her next step is college; she wants to be a physician, a scientist, and an astronaut. Then, its to Mars.

Kids are not the future; we are here now. We are not going to change the world someday; we are already doing it, Taylor said.

Taylor Richardson, The Black Friend Challenge, The Bolles School

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Japanese startup to carry UAE lunar rover to the moon in 2022 – The Japan Times

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Japanese startup ispace Inc. will deliver a lunar rover under development by the United Arab Emirates to the Moon next year in what will be the Arab worlds first lunar mission.

Under the contract recently announced by the Tokyo-based space company and the Mohammed Bin Rashid Space Centre, Dubais governmental space agency, ispace will also provide communications and power during the journey to the moon and on its surface.

The UAEs rover will be loaded onto a lunar lander that ispace plans to launch from Florida in the United States using a rocket made by SpaceX, officially known as Space Exploration Technologies Corp. and founded by tech billionaire Elon Musk.

The Rashid rover, weighing 10 kilograms and measuring about 50 centimeters in length and width and 70 cm in height, will be transported in ispaces lander currently under development. The project will mark ispaces first space mission since its establishment in 2010.

We are very honored that MBRSC has selected ispace to play a key role for this historic moment, Takeshi Hakamada, CEO and founder of ispace, told an online news conference. Furthermore, we are very pleased to advance our collaboration between the UAE and Japan in space exploration.

If the mission succeeds, ispace could become the first private Japanese firm to land on the moon.

The company has also been chosen by the U.S. National Aeronautics and Space Administration to join its project to collect lunar regolith from the Moons surface as part of NASAs Commercial Lunar Payload Services program.

Adnan Al Rais, MBRSCs senior director in its Remote Sensing Department who also attended the news conference, said that his nation chose the Japanese firm as its partner because of their capability, strong team and their leading in this field.

The Middle Eastern country is seeking to diversify its oil-dependent industrial structure by expanding its space exploration program.

In February, its Hope probe successfully entered the orbit of Mars after being launched from Tanegashima Space Center in Kagoshima Prefecture, southwestern Japan, last July. The UAE also has a project to build a human colony on Mars by 2117.

The upcoming lunar mission will represent a milestone in the UAEs space sector as it is expected to provide valuable scientific data and information crucial for the long-term Mars initiative, said Al Rais, who also oversees MBRSCs Mars 2117 program.

Currently, only the United States, Russia and China have succeeded in putting a spacecraft on the surface of the moon.

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Out of thin air: This company has found a way to produce oxygen from soil on the Moon – Euronews

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Over 50 years have passed since man first landed on the Moon, a feat that has remained an enduring symbol of human progress and technological ingenuity ever since.

But in the 21st century, private aerospace companies like SpaceX, Blue Origin and Virgin Galactic have thrown open the door to the real possibility of human beings becoming an interplanetary species.

Despite this centurys massive leaps in making space travel more affordable, there remain huge logistical challenges to making this dream a reality. Chief amongst these is the need to sustain spaceflight and extraterrestrial colonies with a locally-produced oxygen supply.

Oxygen is a hot commodity in space. It will be vital not only for potential human settlements to breathe, but also to enable the combustion processes needed to propel rockets to and from celestial bodies.

Nowadays, its often the case that 70 per cent of a rockets cargo consists of the oxygen needed to launch the spacecraft, which must be carried with it from Earth.

One of the main challenges is the extraordinary cost of sending anything from Earth to the Moon, Jonathan Geifman, the co-founder of Israeli company Project Helios, told Euronews.

His company is currently developing a system to extract and produce oxygen and metals from lunar soil.

It's estimated in the area of $1 million (832,951) per kilogram, so running the numbers, you can immediately understand that this is not sustainable economically. In the long run, we must be able to utilise and use resources on site, he added.

Project Helios, which is backed by the Israeli Energy Ministry and the Israel Space Agency (ISA), has developed an electrochemical reactor capable of extracting oxygen, metals and silicon from moon soil in order to enable the eventual establishment of a permanent lunar base.

And while getting humans to eventually establish a sustainable presence on the Moon is the aim of NASAs Artemis programme, which was launched in 2017, the ultimate prize is sending a crewed mission to Mars.

Its a goal that some, like Jeff Bezos, believe will not be possible without first establishing a lunar base.

If youre gonna need a lot of supplies and fuel and bulk materials to go to Mars, youre much better lifting them off the Moon than you are lifting them off the Earth, Bezos said in an interview at the JFK Space Summit in 2019.

Its an illusion that you can skip a step, he added. Skipping steps slows you down, its seductive but wrong.

In any case, sustaining life on the Moon or Mars will depend on the kind of technology that Project Helios is developing. So, how does the process work?

We are using a process called molten oxide electrolysis, said Geifman.

Just like electrolysing water [where] you split hydrogen from oxygen, we're trying to do the same thing with molten lunar soil.

This process will work pretty well on the Moon, on Earth and on Mars, Mars and actually probably any other planetary body or moon that has soil, sand or whatever on it.

While the company remains focused on their extraterrestrial ambitions, Geifman believes the technology they have developed could also be put to good use here on Earth.

He points to the high polluting arms trade as one example of an industry that could benefit from a more environmentally-sound method of metal production.

Working on these technologies immediately puts us in a completely different frame that allows us to think of new ways of developing technology that must be super efficient environmentally. he said.

When we produce oxygen out of the lunar surface, the by-product we get [is] iron, we get silicon, etc. we can use the same process here on Earth to produce iron. And instead of carbon dioxide as a by-product, we get oxygen instead of carbon dioxide.

According to Geifman, Project Helios won the support of the Israeli Ministry of Energy precisely because they see the potential for a terrestrial application of the technology they are developing.

The challenge facing it - as is often the case for young companies - is scaling up the processes. This is the main focus of their work at the moment.

But Geifman is hopeful about the timeline for Project Helios technology to be up and running on the Moon.

I think that the most optimistic scenario - stars will align in the sky and everything will be just perfect and the whole value chain will function and work - that would be 10 years, he told Euronews.

Thanks to the privatisation of the space industry, companies like SpaceX, it seems more reasonable than ever before. I mean, things are moving faster and faster. And I'm optimistic.

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Will Mars ever be habitable? – The Daily Star

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Elon Musk's mission to populate Mars seems to be always on trend, even when nobody is particularly talking about it. It's been several years since the announcement of such an endeavour, and in 2020 we've seen some stories about the first space crew for this grand mission (even though nothing has been finalised). Once they will set foot on Mars, there's no turning backother crews in batches will likely join them, and then colonies, cities and civilisations will be formed on the Red Planet, and it will cease to be one of the lonely occupants of our universe, hanging around through the passage of time.

At least, that's the plan, but as we all might have guessed, landing humans on Mars isn't the only difficult part of the mission. Living there is a greater challenge. Mars is not Earth, it has its own identitythe arid world doesn't compare to the bearer of about 75 percent water on its surface. So, the real mission is making Mars habitable for humans.

The first colonisers will be given the task of turning Mars into an environment which can sustain life. Simply put, they need to "terraform" Mars, which means the Martian atmospheric conditions need to be manipulated to make them more like that of Earth, so that humans can live, breathe and reproduce freely.

Surely, that is not going to be an easy undertaking. However, Robert Zubrin, in his celebrated book The Case for Mars, is able to a put the subject in an optimistic light. His argument is that if Earth could be made into a self-sustainable planet, the same can be done to Mars.

In its infancy, Earth did not have any oxygen and was barren, much like Mars is now. Only due to the presence of photosynthetic organisms, which used carbon dioxide up and gave out oxygen, the composition of Earth's atmosphere had evolved, leading to the evolution of human beings. So, if the atmosphere of Mars can be manipulated to make it denser and warmer, theoretically it could also support life.

We understand what needs to be done, but how exactly can we go about making Mars hospitable to humans? The answer may lie in the reservoir of carbon dioxide present in the ice caps or under the soil surface on Mars. Carbon dioxide, among other things, is infamous for being a greenhouse gas and contributing to global warming on Earth. We may not want Earth to heat up as a result of global warming more than it has already, but frankly, Mars could use some greenhouse gases. Zubrin points out that the release of carbon dioxide, methane and the production of chlorofluorocarbons or CFCs could lead to a thicker Martian atmosphere, which will be able to trap heat and make Mars warmer.

To accomplish such a feat, Zubrin proposes some innovative solutions. The first, is using orbiting mirrors to direct heat towards specific areas in Mars' south pole. A temperature rise of five degrees (in Kelvins) would be able to cause the dry ice to evaporate, releasing carbon dioxide. The mirrors could also be used to melt the ice to form liquid water, which can be used in biological reactions. Another far-fetched idea is to build factories which can release halocarbons into the Martian atmosphere. However, setting up factories that can generate a substantial volume of the gases requires a substantial amount of money as well, which is why such a project does not seem feasible to the layman. The third solution is to contaminate Mars with photosynthetic microorganisms such as bacteria. This would lead to the release of ammonia and methane as waste products, which would contribute to the greenhouse effect.

If any of these ideas or even a combination of them can be realised on Mars, it could become less hostile for humans. However, if people dream of walking around Mars without special suits and masks, they need to come up with a plan for oxygenating the atmosphere. For this, simple organisms will not be enoughlarge volumes of oxygen are required to support advanced life forms. Genetically engineered plants that can carry out photosynthesis in harsh Martian conditions can provide a solution. The idea is to increase the volume of gases in the atmosphere bit by bit, and as it warms up it can support more advanced plant life. This goes on in a cycle that can be continued until the conditions are suitable for humans.

However, this process would take centuries if the plan is to terraform Mars completely. Instead, "Paraterraforming" can provide a solution for the moment. Here, domes can be built to form an enclosed space that humans can live in. Microbial reactions with the carbon rich Martian soil that can give off oxygen will occur in that restricted region, but out of that enclosed sphere, life would not be supported. The advantage here is that less time and resources will be used. Carrying such a project out is not impossible; in fact, a few years ago, scientists at a company called Techshot had successfully used microbes to create a self-sustaining ecosystem within a localised region that mimics Mars' harsh atmospheric conditions.

Theoretically, everything seems possible, and recent news about the conversion of carbon dioxide on Mars to oxygen by NASA's Perseverance rover is giving us hope that theories can be put to practice. At this point, landing a spacecraft on Mars with humans is a challenge, judging by the sheer amount of time it takes to complete the journey. The first humans to land on Mars will have to build the "biodomes" where further experiments can be carried out and crops can be grown under controlled conditions. Also, resources that are not readily available on Mars need to be made on Earth and imported to Mars. Are we going to be able to devote vast amounts of resources and time to such an endeavour? Will the money required for such a venture be better spent if we were to spend it on Earth? These are some of the questions that could be asked before we take on the challenge of turning Mars into another Earth. We need to keep in mind that the first step a human takes on Mars will be just thatthe first step. There is a long way to go from there, and it will be interesting to see how that story unfolds in the near future.

Protiti Rasnaha Kamal holds a BA in Neuroscience from Mount Holyoke college, USA. She can be reached at protitirasnaha@gmail.com.

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Earth in the Balance: Andy Weir’s Project Hail Mary – tor.com

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Back in 2014, Andy Weirs The Martian became a surprise hit novel, and then an inevitable hit Matt Damon movie. The story of a man accidentally abandoned on Mars and his fight to survive by sciencing the shit out of his impossible situation was immediately captivating. Weir followed this up with Artemis, about a mystery on a moon colony, and now hes back with an interstellar thriller, Project Hail Mary.

I went into this book a near-tabula rasa. All I knew was that it involved an interstellar journey by an astronaut on a last-ditch mission to save Earth. Now, heres the thingif you havent read the book, I recommend you go into it with as rasa a tabula as possible, because this sucker is so crammed with plot twists and reversals that the less you know the more fun its going to be.

To be clear, theyre not gratuitous plot twists. Much as he did in The Martian, Weir sets up a couple base problems and then works through them, inexorably. Sometime there are solutions, sometimes not, and sometimes the solutions breed new problems that need to be dealt with. You can practically hear him backing his main character, Ryland Grace, into new and more difficult corners, then asking, OK, how do I get him out of this? This is the fun of the book.

Without getting into details (for now), Project Hail Mary becomes three or four different books over the course of its plot. While it suffers from some clunky sections, and more exposition than it needs, its also an engaging thriller with some genuine heart and emotional heft. If you enjoyed The Martian and/or Artemis I think youll love it. But to really dig in, to paraphrase Mark Watney, Im gonna have to spoil the shit out of this. If you havent read it, you should bail out now.

For the rest of you, lets get spoilery:

SPOILERS AHOY!!!

Book #1: A Martian-esque survival thriller! This is probably the second strongest thread. As in The Martian, Weir sets his stakes very high and then ratchets them up to incredibly stressful levels. We learn very quickly that our Sun is dimming because of an alien element called Astrophage. This means that Earth is doomed to another Ice Agewith only about thirty years to prepare. Were pretty much fucked. To try to cope, all the Earths major governments band together for Project Hail Mary, studying the Sun, diagnosing the problem, and building a ship to try to solve it. One of the joys of the book is seeing everyone set their differences aside to work together as a species. As Grace travels into space, deals with the Astrophage, and tries to figure out ways to send life-saving info back to Earth, each solution he comes up with has drawbacks, risks, downsides, consequences. He almost dies, a lot.

Book #2: A surprisingly heartwarming First Contact story! Heres where those of you who have read the book are nodding at my decision to bury this under a spoiler line. I had no idea there were aliens in this sucker? Im just reading along, like, gosh, is Grace going to figure out the Astrophage? Will there be any way to get home, or is he really doomed? And then WHAM! Alien ship! Right there! And here again, Weir thinks of a problem: what if Grace has to handle First Contact, alone in space, with no backup, and no obvious way to communicate? How would a person work through that kind of stress? I loved watching Grace and the alien he comes to call Rocky gradually build communicationthough I do think it was a little too easy at some points. And I loved Rocky. But for me the element that really got to me was thinking about Rockys intense bravery. To be alone for as long as he was, see an alien ship, and make the terrifying choice to reach out to an alienespecially as Weir lets us learn about his intensely communal species, and just how lonely and terrified he must have been. I also appreciated the fact that this First Contact story casts the human as well-meaning but not always heroic, allowing the alien to be the real star of the show for sections of the book.

Book #3: The ongoing taxonomy of an alien species! Ryland Grace is the first person to meet an alien who is sentient by our definition of the term. He has to describe Rocky, work through how he thinks, eats, sleeps. He has to try to help him when hes injuredand his efforts are somewhat disastrous. He has to deduce ideas about Rockys planet, civilization, and cultural history. And Weir does all that, and gives us a bunch of worldbuilding of an alien civilization, through conversations and monologues between characters in a three-room spaceship.

Book #4: A story about Earth apocalypse! This one is, I would argue, considerably weaker. I never had a sense of how much time was spent on Project Hail Mary. While I liked Graces boss Stratt being a merciless hard ass who has to do an impossible job, I think more time could have been spent making her real and complicated, and showing her character rather than telling us about it via Graces snarky monologues. The catastrophe that face humanity was so enormous that I thought Weir needed to check in on it a bit more often, and with more in-scene action. For instance, the idea of an environmental scientist nuking Antarctica is terrifying, and I think spending more time on that, building up to that scene, would have been much more effective than the later monologue Weir gives to Stratt. Hearing her outline how much of a hell the Earth is about to become, and hearing her justify her attempts to give humanity a chance, was a fun twist on a classic villain speechbut it would have been far more powerful if we had seen more of Earths collapse along the way. Also, just the throwaway line that Stratt fully expects to live through Earths collapse in a prison cell after all the governments prosecute her for all the laws she brokein a way shes as doomed as Grace is, and I think playing with that more, and in more subtle way, would have served the story better and added to the tension in Book #5. Speaking of

Book #5: Both is and isnt the book I hoped we were getting! As soon as its clear that Grace has woken up with amnesia, and keeps talking about how much he wished he could remember leaving Earth, I began to suspect that the truth of his heroic mission was more complicated than he thought. I love that Weir went with Grace was literally drugged, kidnapped, and sent to his doom after saying no rather than heroic schoolteacher acts heroic. Its such a great thread to weave through, when even Rocky refers to both of them as good people because of their sacrifices, to have the rug pulled out from under Grace and the reader. I especially like the idea that here is a schoolteacher who could be seen as kind of a riff on (actually heroic) Christa McAuliffewe want to believe that this cool teacher is a renegade scientist who makes a huge sacrifice. Instead, Grace is a promising academic who fled his field rather than challenge himself. Hes a cool teacher, but he throws his kids under the bus and claims he needs to stay on Earth to teach them how to survive an apocalypse, which is absurd. He knows for months that hes coma resistant, but never discusses it with Stratt or offers to go. He jeopardizes the whole mission with his refusal to join, even though it will, at best, only buy him about a decade of increasingly shitty life on an unstable planet.

All of this is great. My one issue with it is that I think, again, Weir should have let Grace, and us, sit with that discovery for a while longer. Im personally pretty unsure of my own capacity for heroism, but I know that if Id spent a few months thinking I was a hero, while piecing my whole life together after amnesia, and then found out I was actually a coward who almost doomed my planet? Id be catatonic for a while.

But having said that, how great is it when Grace realizes exactly what he and Rocky did wrong, and how, even if he makes it back, Rockys doomed after all? The whole fantastic rollercoaster of Grace thinking hes a dead man walking, discovering he can go home after all, realizing that he was a coward but that now he gets to go home to a heros welcomeonly to realize that he has to actually make the heroic sacrifice to save Rocky and the Eridians?

Project Hail Mary is available from Ballantine Books

Leah Schnelbach might be coming around on the whole going to space idea. Come talk to them about interstellar travel on Twitter!

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Earth in the Balance: Andy Weir's Project Hail Mary - tor.com

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