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Monthly Archives: February 2021
Health Canada approves DUPIXENT (dupilumab injection) as the first biologic for the treatment of moderate-to-severe atopic dermatitis in children aged…
Posted: February 25, 2021 at 1:22 am
MISSISSAUGA, ON, Feb. 23, 2021 /CNW/ - Sanofi Canada announced today that Health Canada has approved DUPIXENT (dupilumab injection) for the treatment of moderate-to-severe atopic dermatitis (AD) in children aged six to 11 years whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable.3
"As the first biologic treatment for atopic dermatitis approved for this age group, DUPIXENT is a promising new option for treating children living with this chronic disease," says Dr. Melinda Gooderham, Dermatologist and Medical Director at the SKiN Centre for Dermatology. "Because it targets type 2 inflammation, the underlying cause of the disease, it may help young patients gain more control over their symptoms during childhood, a pivotal time in their development."
DUPIXENT is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL-4) and interleukin-13 (IL-13) proteins and is not an immunosuppressant. Data from DUPIXENT clinical trials have shown that IL-4 and IL-13 are key drivers of the type 2 inflammation that plays a major role in AD, asthma, and severe chronic rhinosinusitis with nasal polyposis (CRSwNP).4
AD, the most common form of eczema, is an inflammatory disease classified by dry, itchy skin. In its moderate-to-severe form, it is characterized by rashes that can cover much of the body, and can include intense, persistent itching, skin lesions and skin dryness, cracking, redness or darkness, crusting and oozing.5 Inadequately controlled AD can have a physical, emotional and psychosocial impact, causing sleep disturbance, symptoms of anxiety and depression, and feelings of isolation.6
For children living with AD, studies showed that the impact extends beyond its physical symptoms. A survey conducted by the Eczema Society of Canada among Canadian children from infancy up to the age of 18 (and their caregivers) living with AD found that 70 per cent experienced loss of sleep due to their condition, 20 per cent missed school days and 30 per cent experienced anxiety.7 These factors can have a negative psychological impact on children, particularly in regard to their concentration and performance at school along with their willingness to socialize.8
"Atopic dermatitis is a chronic disease that has an indelible impact on all patients, both physically and psychologically, and can be devasting to children during a vulnerable time in their life," says Marissa Poole, Country Lead, Sanofi Canada and General Manager, Sanofi Genzyme Canada. "With this new indication, DUPIXENT now has the potential to help the many Canadians who experience this disease including children, adolescents and adults."
About DUPIXENT
Since its initial approval in 2017, DUPIXENT remains the only biologic medicine approved by Health Canada for the treatment of patients six years and older with moderate-to-severe AD whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable.9 DUPIXENT is also approved in Canada for the treatment of adult patients with severe CRSwNP and for the treatment of severe asthma in patients 12 years and older.10
DUPIXENT is jointly developed by Sanofi and Regeneron under a global collaboration agreement.
About Sanofi
Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.
With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe.
Sanofi entities in Canada employ approximately 2,000 people. In 2018, we invested more than $127 million in R&D in Canada, creating jobs, business and opportunity throughout the country.
Follow us on Twitter @SanofiCanada and on YouTube.
Sanofi, Empowering Life
References
___________________________________
1 Ben-Gashir MA, Seed PT, Hay RJ. Quality of life and disease severity are correlated in children with AD. Br J Dermatol. 2004;150(2):284-90. Available from https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2133.2004.05776.x?sid=nlm%3Apubmed. Accessed February 19, 2021.
2Eczema Society of Canada. Atopic Dermatitis Quality of Life Report. Available from https://eczemahelp.ca/wp-content/uploads/2019/02/ESC_Quality-of-Life-Report_Nov-2017-1.pdf. Accessed February 19, 2021.
3 DUPIXENT Canada Product Monograph. February 22, 2021.
4DUPIXENT Canada Product Monograph. February 22, 2021.
5 Mount Sinai. Patient Care Atopic Dermatitis. Available from http://www.mountsinai.org/patient-care/health-library/diseases-and-conditions/atopic-dermatitis#risk. Accessed February 19, 2021.
6 Eczema Society of Canada. Atopic Dermatitis Quality of Life Report. Available from https://eczemahelp.ca/wp-content/uploads/2019/02/ESC_Quality-of-Life-Report_Nov-2017-1.pdf. Accessed February 19, 2021.
7 Eczema Society of Canada. Atopic Dermatitis Quality of Life Report. Available from https://eczemahelp.ca/wp-content/uploads/2019/02/ESC_Quality-of-Life-Report_Nov-2017-1.pdf. Accessed February 19, 2021.
8 Sick Kids. Eczema: School and activities. Available from https://www.aboutkidshealth.ca/Article?contentid=1113&language=English. Accessed February 19, 2021.
9 DUPIXENT Canada Product Monograph. February 22, 2021.
10 DUPIXENT Canada Product Monograph. February 22, 2021.
SOURCE Sanofi Canada
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Health Canada approves DUPIXENT (dupilumab injection) as the first biologic for the treatment of moderate-to-severe atopic dermatitis in children aged...
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Mums agony at sons screams from blistered skin and bowel movements like acid water – The Sun
Posted: at 1:22 am
A MUM has described how her sons milk allergy left him skin blistered from head to toe and his poo like acid water.
Charlotte Smallwood, 25, says her baby Arthur screamed in pain and was "inconsolable" for seven months before he finally got the treatment he needed.
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Doctors reportedly misdiagnosed Arthur, now 10 months old, with colic - when babies cry an abnormal amount - and acid reflux.
But Charlottes first child, three-year-old Thea, had suffered from both of these conditions, and she thought there was something more to Arthurs suffering.
The mum believed that milk was the problem but claims doctors continuously insisted Arthur did not have a cow's milk protein allergy (CMPA).
She and husband Lewis, 28, tried steroid creams, bath creams and milk formulas prescribed by doctors to help their constantly upset and sleep deprived baby - but to no avail.
Eventually, dermatologists at a children hospital urgently requested to see Arthur and were reportedly shocked and disgusted at his treatment to that point.
They prescribed a regime that worked miracles within 24 hours, according to Charlotte, who said Arthur was laughing and rolling around within a week.
Now, Arthur only has flare ups of his allergic symptoms.
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Charlotte, from Romford, Essex, said: The eczema and reactions grew worse and worse, and in the end his skin was reacting to everything that went into or onto his body.
His skin and bowels would bear the brunt of his reactions he would have uncontrollable bowel movements that were like acid water, which left him blistered and raw.
It seemed as though whatever had just gone into him was trying to get out via his skin.
He couldnt do anything he never laughed, couldnt roll, sit up, play or grab things.
Charlotte felt overwhelmed trying to help her son when everything seemed to either have no affect or make him worse.
She said: The toughest part was watching Arthur scream, cry, scratch, throw himself around and bleed.
He would be absolutely uncontrollable and inconsolable.
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Knowing that there wasnt anything that I could do to help my child was absolutely heartbreaking.
Charlotte noticed problems with baby Arthurs skin the day after he was born in April 2020.
His face was patchy and swollen, which doctors reportedly dismissed as baby acne and swelling due to being born by caesarean.
But when Arthur was taken home and started having infant formula, he began suffering episodes of screaming after eating, vomiting up the formula and arching his back in pain.
After swapping Arthur's milk back to pre-made bottles she saw an improvement in his behaviour but the symptoms soon started up again.
She tried over the counter colic and reflux medicines - after Arthurs GP suggested this was the cause - but nothing helped the poor baby.
Arthur was also suffering with severe cradle cap and constipation, and at four weeks old patches of eczema appeared on his cheeks and arms.
From one to four months old, I was back and forth on the phone to the doctor, Charlotte said.
He was given antibiotics, mild steroid creams, bath creams and over the counter creams nothing helped, it just made him worse and worse.
Some creams would even make him look as though he had been burned.
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Cow's milk allergy - the facts
Cows milk protein allergy (CMPA) is one of the most common food allergies to affect babies and young children in the United Kingdom it is still rare.
Symptoms of CMPA often start in the early weeks and months of life.
It affects formula fed babies, but also breastfed babies in very rare cases.
CMPA is an abnormal response by the bodys immune system in which proteins in cows milk are recognised as a potential threat.
This can causethe immune system to be "sensitised". When this happens, there is the potential that when cow's milk is consumed the immune system remembers this protein and may react to it by producing allergic symptoms.
Allergic symptoms can affect one or more of thebodys systems, including the skin, digestive and, less commonly, breathing or blood circulation.
The symptoms can be "immediate", within a few minutes of consuming cows milk or up to two hours afterwards.
The other type of milk allergy happens when symptoms are "delayed", appearing up to 72 hours after cow's milk consumption.
This is caused by a different part of the immune system reacting ina different way.
If cows milk continues to be consumed in the diet, the immune system will continue to produce such symptoms over days or even weeks.
Source: Allergy UK
Unable to get a face-to-face appointment due to Covid-19 restrictions, Charlotte took Arthur to A&E.
Within 10 minutes, he was diagnosed with CMPA and severe infected eczema.
CMPA is when the immune system sees proteins in cows milk as a threat.
It can cause the immune system to be sensitised - it recognises the protein and produces allergic symptoms every time it sees the protein, according to Allergy UK.
This can affect the skin, digestive system, breathing and blood circulation.
Doctors prescribed Arthur a new formula, stronger steroid creams and bath creams, and within a week his skin started to clear up.
But when Charlotte tried to wean him off it, the skin issues came back with a vengeance.
She said: The sleep deprivation was something else I went seven months without sleeping more than three hours of broken sleep a night.
Arthur would just scratch, cry and scream all night long. I had to wrap his arm up close to his body just so he would stop scratching for five minutes.
His sister would get very upset watching him and it was tough trying to explain things to her.
She would give me a cuddle when I would break down in tears, which was a lot.
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In October, Arthur was taken again to A&E after a bad reaction to a teething gel.
His dietician pushed for an appointment at Homerton University Hospital in London for allergy tests when he was seven months old.
Sadly, the condition of his skin was then too severe to carry out allergy testing and his body was 98 per cent covered in severe eczema.
We went home feeling very deflated and wondering how long we would have to wait for someone to see him again, Charlotte said.
But I received a phone call the next day from the Homerton childrens dermatology department asking me to take him there that second we couldnt believe it.
When Arthur was seen by the specialists, Charlotte said they were "shocked" and disgusted by how previous doctors had cared for his skin and couldn't understand how he had been left so long without proper treatment.
His new dermatologist gave him a strict skin routine which they said should help within one week.
It involved three different ointments, a gel for his scalp, and a special bath product.
Charlotte would apply steroid ointments over his whole face and body in the morning, followed by a cream 15 minutes later.
She had to reapply the cream every two hours, which dropped to every four hours in the second week.
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The mum said: At the time, I was very sceptical and didnt believe them, but he was clear in just 24 hours.
By the end of the first week, he was laughing, rolling, sitting up, grabbing things and playing.
I could change his nappy on my own without him scratching and he slept through the night for the first time ever.
His big sister found it so amazing that she could finally play with her baby brother as she couldnt touch him before.
Now, sweet Arthur is flourishing and only suffers mild eczema flare-ups occasionally, caused by environmental factors such as dust and washing detergents.
He is still on the special formula but is weaning and loving all of his food, having had his allergies retested.
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Charlotte is careful to read food labels to ensure no dairy gets into Arthurs diet, which would cause another devastating flare-up.
She added: A lot of doctors seem very standoffish when it comes to CMPA, sort of like they dont believe its a real allergy.
I have come across many people and children like our family that have gone through the same situation.
But do not give up and dont be scared to go over somebodies head to get to where your child needs to be.
Arthur is now a happy, healthy 10-month-old who is thriving he has come so far.
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Eczema Therapeutics Market 2020, Global Statistics, Facts and Figures, Investment Trends, Analysis Of Major Manufacturer Trends and Forecast By 2026 -…
Posted: at 1:22 am
Eczema Therapeutics Market Report 2021: To Know the impact of COVID-19 on the global market, Request For Free Sample
The Eczema Therapeutics Market Report is a systematic survey of the global Eczema Therapeutics market that depicts shows the current state of the business at the observatory. The Supply and demand, revenue estimates, and volume share are widely covered in the report. This predicts market progress over the forecast year 2020 to 2027. The report includes key strategies of companies operating in the market and their impact analysis. The report features an outline of the determined vendors of the market along with an overview of the major market players. Thekey players in the Eczema Therapeutics market areEncore Dermatology Inc, Eli Lilly and Co, Sanofi, LEO Pharma AS, Alliance Pharma Plc, Pfizer Inc, AbbVie Inc, Mylan NV, Bausch Health Companies Inc, Bayer AG.The report contains inventions that provide revenue segmentation and business overview, layouts for key market players. It takes into account the latest enhancements in the global Eczema Therapeutics market while assessing the market share of key players over the forecast period 2021-2027. The report estimates growth in the global Eczema Therapeutics market by estimating the limits and strengths of key players through SWOT analysis. In addition, the report highlights key product overviews and Market segments [By Product Type: Atopic Dermatitis, Contact Dermatitis, Others], and global market subsegment By Application: Hospital, Clinic, Others of the global market
Download FREE Sample Report:@ https://www.globalmarketers.biz/report/life-sciences/global-eczema-therapeutics-market-report-2020-by-key-players,-types,-applications,-countries,-market-size,-forecast-to-2026-(based-on-2020-covid-19-worldwide-spread)/154779#request_sample
This study analyzes the economic adverse effects of COVID-19 with Eczema Therapeutics supply chain scenarios, global demand, and consumers are analyzed in this report. It also provides a robust Eczema Therapeutics business strategy adopted by industry players to gain traction in the industry. It provides detailed info on marketing channels, upstream raw material suppliers, and downstream buyer analysis.The extensive assessment of Eczema Therapeutics manufacturing processes, consumption patterns, company profiles, and gross margins has been analyzed in this study. It also provides additional evaluation/analysis on pricing and demand for each product type, application, the end-users study is also offered in this research. The opportunities, restraints, growth drivers, future trends are presented effectively by Global Marketers
Main highlights from the table of contents:1. Market overview
MarketScope
Definition, classification, purpose
Eczema Therapeutics market momentum, opportunity map analysis
Analysis of market concentration and maturity
2. Market segmentation
Industry classification by top companies
By product type
Depends on the application and end-user
3. Regional diversification of the Eczema Therapeutics industry
North America
Europe
Asia Pacific
Latin America
Middle East and Africa
Other parts of the world
4. Competitive analysis
Market share, sales, revenue analysis
Import-Export details, supply and demand statistics
M & A, growth strategies, opportunities, and risk assessment
5. Important data coverage by region
Volume and value analysis
Consumption and market share survey
Revenue, price trends, and market size assessment
6. Manufacturer/Top Company Profile
Business overview
Eczema Therapeutics product analysis
Sales by region
Price, revenue, gross profit
7. Global Eczema Therapeutics Market Forecast by Type, Application, and End User
Forecast by size, share, and revenue
Predict growth opportunities, investment scope, and development
Pricing, consumption, and volume forecasts for Eczema Therapeuticss
8. Important survey results and survey methods
9. Reliable data source
10. Conclusions, analysts opinions, and appendices
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Earth Notes: The Benefits Of Showering Less – KNAU Arizona Public Radio
Posted: at 1:22 am
Showering is a significant use of water in American homes. On average, individuals typically take 8-10 minute showers every day, using about 17 gallons of water each time.
If everyone in the city of Flagstaff with its current population took showers like that - 365 days a year - it would add up to almost 460 million gallons of water annually; an amount equivalent to about 10% of the water in Lake Mary when its filled to the brim.
For residents of the Prescott Quad Cities area, those long showers add up to just over 800 million gallons a year, or about half the water in Watson Lake when its full.
Water consumption in Arizona has held steady and even declined over the last few decade - in part because of the Groundwater Management Act of 1980, which restricted irrigation on new farmland in urban areas. Even so, showering can still account for up to 20% of a persons average use of 84 gallons a day.
Cutting down on personal water usage can be as simple as installing low flow shower heads and showering half as long or half as often. An added bonus of not showering every day is that its good for our skins microbiome.
These natural communities on our skin, create antimicrobial substances that compete with unwanted pathogens. A healthy microbiome helps protect us from those bugs and can reduce skin infections like eczema.
Taking shorter, less frequent showers is not only a good way to conserve local water resources, it can also be good for our health.
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Earth Notes: The Benefits Of Showering Less - KNAU Arizona Public Radio
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How to treat your stressed-out skin | US & World News | kctv5.com – KCTV Kansas City
Posted: at 1:22 am
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How to treat your stressed-out skin | US & World News | kctv5.com - KCTV Kansas City
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Kawakawa innovation: NZ researchers to trial beverage for immunity, metabolic health gains – BeverageDaily.com
Posted: at 1:22 am
Kawakawa (Piper excelsum) is traditionally used by the indigenous Maori for medical purposes such as pain relief, alleviating eczema, and rheumatism. It is also used as a spice in the everyday cuisine.
Researchers at the Liggens Institute, University of Auckland, have been studying the plant for years and their project was recently granted nearly NZ$1.3m (US$949k) by the High-Value Nutrition (HVN) Science Challenge.
The eventual goal is to launch a functional drink by homegrown beverage firm Chia Sisters, while Wakatu Incorporation will export the product to Japan and South East Asia. The kawakawa used in this project is the Aotearoa New Zealand native species.
At the moment, the researchers are now planning two trials to test the optimal dosage amounts and the best suited beverage formats.
Kawakawa contains pharmacokinetic metabolites with interesting structures and properties. We suspect it could increase the uptake of nutrients or make nutrients more bioavailable in the body.
Some of its compounds can affect the way we metabolise glucose and fatty acids, lead researcher of the project, Dr Chris Pook from the Liggens Institute told NutraIngredients-Asia.
The first trial, which will take place later this year, will be a one-day study that looks at the short-term effects of kawakawa on fatty acid and glucose metabolism.
Participants will need to try out kawakawa in varying dosage amounts and dosage formats.
From here, researchers will measure the participants energy expenditure, as well as the amount of heat and carbon dioxide the body produces, before deciding the formats and dosages for the second trial.
Running for six weeks, the second trial will track the effects of the kawakawa beverage over time.
As part of the project, the researchers are also finding out ways to maximise their extraction of kawakawas bioactives.
The industry partner involved, Wakatu Incorporation, also intends to make functional claims on the final product.
For instance, when exporting to Japan, it plans to register the product as a Foods with Function Claims (FFC), Miriana Stephens, general manager at Wakatu Incorporation said.
This is also the first time the distributor is working on a functional beverage.
We export New Zealand food and beverages including seafood, wines, and natural foods to over 40 countries, the functional beverage space is completely new for us and we will work closely with our customer on refining the product, she said.
Ready-to-drink kawakawa beverages already exist in the New Zealand market.
Last year, Atutahi, a local carbonated drink brand containing kawakawa was launched.
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The Mild To Moderate Atopic Dermatitis Treatment Market to move on a positive note between 2020 and 2030 Atlantic Financial Management – Atlantic…
Posted: at 1:22 am
Mild-to-moderate atopic dermatitis is a chronic inflammatory skin disease often confined to the flexural surfaces of the body and usually begins in childhood. This skin disease affects a large percentage of the worlds population. Atopic dermatitis is also known as eczema which is characterized by itching, swelling, dry skin, redness, vesicle formation, crusting, cracking, scaling and weeping. Atopic dermatitis is a long-term skin disease, which is classified into different types depending on the skin condition such as contact eczema, allergic contact eczema, neurodermatitis, dyshidrotic eczema, nummular eczema, stasis dermatitis and seborrheic eczema. Multiple factors are responsible for mild-to-moderate atopic dermatitis which include low humidity, cold weather, seasonal allergies, and exposure to harsh soaps and detergents.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Drivers and Restraints
Large patient population and new product launches are factors projected to drive the growth of mild-to-moderate atopic dermatitis treatment market globally. According to the United Nations Population Fund (UNFPA), the global population is growing at a rate of 1.1%. Climatic changes and large pipeline products are factors which are estimated to fuel the growth of this market. However, stringent regulations for product approvals and generic competition are the factors which hinder the market growth of mild-to-moderate atopic treatment market globally.
Mild-to-Moderate Atopic Dermatitis Treatment Market: Segmentation
By treatment type the mild-to-moderate atopic dermatitis treatment market can be segmented into
By distribution channel the mild-to-moderate atopic dermatitis treatment market can be segmented into
Drug treatment can further be segmented into antihistamines, antibiotics, emollients, corticosteroids, and calcineurin inhibitors. Topical corticosteroids are the standard treatment for most patients with atopic dermatitis for more than 50 to 60 years. Calcineurin inhibitors are used as second line treatment drug for atopic dermatitis. Recently the U.S. Food and Drug Administration has approved Eucrisa a topical treatment for children and adults with mild-to-moderate atopic dermatitis. Eucrisa works differently than other topical treatments on the market.
Mild-to-Moderate Atopic Dermatitis Treatment Market: Overview
The medication treatment of the skin disease depends on the duration, pattern, and severity of the skin lesions. Except drug therapy, atopic dermatitis is treated with ultraviolet light therapy. According to the American Academy of Dermatology (AAD), the atopic dermatitis that emerges in adults is often different and more severe than infants and children. According to Anacor Pharmaceuticals, Inc., atopic dermatitis is estimated to affect about 18% of infants and children in developed countries. These disease often becomes milder with age.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Region-wise Outlook
Geographically, the market is segmented into North America, Latin America, Europe, Asia Pacific and Middle East and Africa. North America leads the market for mid-to-moderate atopic dermatitis reasons being lifestyle changes, new product innovations, and early treatment adoption. A large proportion of the U.S. population has symptoms of eczema. According to the National Eczema Association in the U.S., approximately 30 million people are living with eczema, and the prevalence rate of childhood eczema is 10.8%. Europe is the second leading market for mild-to-moderate atopic dermatitis treatment due to development activities and large research base. The Asia Pacific market is also expected to grow at a higher rate owing to changing lifestyle, large target patient pool, rapid population growth, adoption of western lifestyle, and growth in research and development. These factor are likely to drive the market growth of mild-to-moderate atopic dermatitis treatment market during the forecast period globally.
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Mild-to-Moderate Atopic Dermatitis Treatment Market: Key Players
The major players in mild-to-moderate atopic dermatitis treatment market include Anacor Pharmaceuticals, Inc., Astellas Pharma Inc., Meda Pharmaceuticals, Novartis International AG, Pfizer Inc., Regeneron Pharmaceuticals, Sanofi S.A., and Valeant Pharmaceuticals International, Inc.. The robust drug pipeline shows that manufacturers see a large potential market for mild-to-moderate atopic dermatitis treatments. For instance, Anacor Pharmaceuticals is developing a drug, crisaborole which is a non-steroidal topical anti-inflammatory for mild-to-moderate atopic dermatitis which can have a significant utilization. Dupilumab is expected to be approved for the treatment of moderate to severe atopic dermatitis in adults.
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Babassu Oil Hair And Skincare Benefits – What Is Babassu Oil? – Women’s Health
Posted: at 1:22 am
Theres a slew of oils out there that claim to have major beauty benefits. And while some of them have definitely become cult-favorites (ahem, coconut oil), others have fallen short. Now theres a newer-to-the-market oil that is impressing users and boasting skincare perks that make it worth mentioning. Enter: babassu oil. While its name may not sound familiar to you yet, this oil may just be the next big thing when it comes to keeping your hair, skin, and body moisturized.
Before adding babassu oil to your beauty routine, you might be curious where it comes from. FYI: It's derived from the seed of a babassu palm tree, which is native to the rainforests of South America, according to board-certified dermatologist Hadley King, MD. Like coconut oil, babassu oil is extracted from the kernels of the trees nuts.
She also notes that in Brazil, the babassu tree is known as the "tree of life," because the oil is thought to have healing properties, and is commonly used in both cooking and beauty regimens across the country. (Consider it the do-it-all oil your busy lifestyle desperately needs.)
Keep reading to learn more about this tropical oil, what its good for, how exactly to use it, and why you need to consider adding it to your hair and skincare routine ASAP.
Since babassu oil is a multitasker, its often compared to the stateside favorite coconut oil. And it's true, if babassu oil had a twin, itd probably be coconut oil, since it's composed of similar fatty acids. Texture-wise, it's also a smooth solid that liquifies once it hits your skin.
You can find it packaged either in a jar in soft solid form, like coconut oil would be, or in an oil dropper for applying it directly to your face or body. It can also be an ingredient in a thicker balm or lotion to lather on and nourish hair or skin.
There are a variety of ways to use this hydrating oil. We typically think of this oil as good for dry skin, but it can also be helpful to combat redness, Miami-based board-certified dermatologist Loretta Ciraldo, MD, FAAD, says. And since its really lightweight and easily absorbed, even those who have oily or acne-prone skin can benefit (more on that later).
Dr. King also notes that its a great oil for smoothing and hydrating the hair and scalp, since its less greasy than other oils.
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While more research and studies are required to understand all the wonders of babassu oil, there are a few known benefits that are worth mentioning.
Like many oils, babassu oil is a moisturizing go-to because it truly hydrates the skin. According to Dr. King, babassu oil contains 70 percent fatty acids, and is unique because it absorbs into the skin very quickly and leaves skin with that cool, refreshed feeling we all know and love.
Dr. Ciraldo agrees, adding that babassu oils hydrating properties are thanks to a high content of lauric acid, which is the same fatty acid that makes coconut oil so hydrating. But since babassu oil is so lightweight, it wont leave your complexion feeling greasy in the same way coconut oil sometimes does.
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The same acid that makes this tropically-derived oil hydrating also makes it antimicrobial. Peer reviewed publications attest to the fact that lauric acid helps to fight against bacteria sometimes found on the skin, including strep and staph, Dr. Ciraldo says. That being said, it's not as effective in treating a skin infection as a prescription topical antibiotic, adds Dr. Ciraldo.
If youve ever had an acne or eczema flare-up, you know how inflamed and irritated the skin can become in what seems like minutes. Because babassu oil has some anti-inflammatory properties, Dr. King says it may be helpful in improving skin conditions, like acne and eczema. One older study found that lauric acid, which is present in babassu oil, may help reduce inflammation and acne-causing bacteria on the skin. Not to mention, since this lightweight oil doesnt clog pores, it makes a great oil choice for those concerned about breakouts and blemishes.
Since research is limited on babassu oil, both Dr. King and Dr. Ciraldo agree that it can be hard to say if there are any downsides to adding babassu oil to your regimen. Dr. King recommends being cautious with this oil if youre allergic to coconut oil, since both of these oils have some of the same properties and make up.
It may be best to avoid using it if youre a pregnant or nursing mama, too, Dr. Ciraldo says, because there havent been any studies in this area. Babassu oil has also been associated with changes in thyroid function in people who have thyroid disease, she notes. So if you have a history of thyroid disease, it may be best to consult with your physician before using babassu oil in any way.
The bottom line: If coconut oil is your holy grail, babassu oil is a must-try for hydrating dry skin and hair, that doesn't clog pores or feel heavy or greasy upon applying.
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Astronomers Make a Weird Discovery: A Concentration of Smaller Black Holes Lurking Where They Expected a Single Massive Black Hole – SciTechDaily
Posted: at 1:19 am
This is an artists impression created to visualize the concentration of black holes at the center of NGC 6397. In reality, the small black holes here are far too small for the direct observing capacities of any existing or planned future telescope, including Hubble. It is predicted that this core-collapsed globular cluster could be host to more than 20 black holes. Credit: ESA/Hubble, N. Bartmann
Astronomers found something they werent expecting at the heart of the globular cluster NGC 6397: a concentration of smaller black holes lurking there instead of one massive black hole.
Globular clusters are extremely dense stellar systems, which host stars that are closely packed together. These systems are also typically very old the globular cluster at the focus of this study, NGC 6397, is almost as old as the universe itself. This cluster resides 7,800 light-years away, making it one of the closest globular clusters to Earth. Due to its very dense nucleus, it is known as a core-collapsed cluster.
At first, astronomers thought the globular cluster hosted an intermediate-mass black hole. These are the long-sought missing link between supermassive black holes (many millions of times our Suns mass) that lie at the cores of galaxies, and stellar-mass black holes (a few times our Suns mass) that form following the collapse of a single massive star. Their mere existence is hotly debated.Only a few candidates have been identified to date.
The amount of mass a black hole can pack away varies widely from less than twice the mass of our Sun to over a billion times our Suns mass. Midway between are intermediate-mass black holes weighing roughly hundreds to tens of thousands of solar masses. So, black holes come small, medium, and large. Credit: NASA, ESA, T. Brown, S. Casertano, and J. Anderson (STScI)
We found very strong evidence for an invisible mass in the dense core of the globular cluster, but we were surprised to find that this extra mass is not point-like (that would be expected for a solitary massive black hole) but extended to a few percent of the size of the cluster, said Eduardo Vitral of the Paris Institute of Astrophysics(IAP) in Paris, France.
To detect the elusive hidden mass, Vitral and Gary Mamon, also of IAP, used the velocities of stars in the cluster to determine the distribution of its total mass, that is the mass in the visible stars, as well as in faint stars and black holes. The more mass at some location, the faster the stars travel around it.
The researchers used previous estimates of the stars tiny proper motions (their apparent motions on the sky), which allow for determining their true velocities within the cluster. These precise measurements for stars in the clusters core could only be made with Hubble over several years of observation. The Hubble data were added to well-calibrated proper motion measurements provided by the European Space Agencys Gaia space observatorywhich are less precise than Hubbles observations in the core.
Our analysis indicated that the orbits of the stars are close to random throughout the globular cluster, rather than systematically circular or very elongated, explained Mamon. These moderate-elongation orbital shapes constrain what the inner mass must be.
Astronomers on the hunt for an intermediate-mass black hole at the heart of the globular cluster NGC 6397 found something they werent expecting: a concentration of smaller black holes lurking there instead of one massive black hole. Credit: NASA Goddard Space Flight Center
The researchers conclude that the invisible component can only be made of the remnants of massive stars (white dwarfs, neutron stars, and black holes) given its mass, extent,and location. These stellar corpses progressively sank to the clusters center after gravitational interactions with nearby less massive stars. This game of stellar pinball is called dynamical friction, where, through an exchange of momentum, heavier stars are segregated in the clusters core and lower-mass stars migrate to the clusters periphery.
We used the theory of stellar evolution to conclude that most of the extra mass we found was in the form of black holes, said Mamon. Two other recent studies had also proposed that stellar remnants, in particular, stellar-mass black holes, could populate the inner regions of globular clusters. Ours is thefirst study to provide both the mass and the extent of what appears to be a collection of mostly black holes in the center of a core-collapsed globular cluster, added Vitral.
The astronomers also note that this discovery raises the possibility that mergers of these tightly packed black holes in globular clusters may be an important source of gravitational waves, ripples through spacetime. Such phenomena could be detected by the Laser Interferometer Gravitational-Wave Observatory experiment, which is funded by the National Science Foundation and operated by Caltech in Pasadena, Californiaand MIT inCambridge, Massachusetts.
For more on this research, read Unexpected Discovery: Hubble Space Telescope Uncovers Concentration of Small Black Holes.
Reference: Does NGC 6397 contain an intermediate-mass black hole or a more diffuse inner subcluster? by Eduardo Vitral and Gary A. Mamon, 11 February 2021, Astronomy and Astrophysics.DOI: 10.1051/0004-6361/202039650
The Hubble Space Telescope is a project of international cooperation between NASA and ESA (European Space Agency). NASAs Goddard Space Flight Center in Greenbelt, Maryland, manages the telescope. The Space Telescope Science Institute (STScI) in Baltimore, Maryland, conducts Hubble science operations. STScI is operated for NASA by the Association of Universities for Research in Astronomy in Washington, D.C.
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Cygnus X-1’s Stellar-Mass Black Hole is More Massive than Astronomers Thought | Astronomy – Sci-News.com
Posted: at 1:19 am
A black hole in the Cygnus X-1 binary system is so massive that it challenges current stellar evolution models.
An artists impression of the Cygnus X-1 binary system. Image credit: International Centre for Radio Astronomy Research.
Discovered in 1964, Cygnus X-1 is an X-ray binary system located in the constellation Cygnus.
The primary star, HD 226868, is a hot supergiant revolving about an unseen compact companion with a period of 5.6 days.
The companion is a so-called stellar-mass black hole, a class of black holes that comes from the collapse of a massive star.
Cygnus X-1 was the focus of a famous scientific wager between physicists Stephen Hawking and Kip Thorne, with Hawking betting in 1974 that it was not a black hole. Hawking conceded the bet in 1990.
Stars lose mass to their surrounding environment through stellar winds that blow away from their surface, said Professor Ilya Mandel, an astrophysicist at Monash University and the ARC Centre of Excellence in Gravitational Wave Discovery (OzGrav).
But to make a black hole this heavy, we need to dial down the amount of mass that bright stars lose during their lifetimes.
The black hole in the Cygnus X-1 system began life as a star approximately 60 times the mass of the Sun and collapsed tens of thousands of years ago, he added.
Incredibly, its orbiting its companion star a supergiant every five and a half days at just one-fifth of the distance between the Earth and the Sun.
Professor Mandel and colleagues observed Cygnus X-1 using the Very Long Baseline Array (VLBA).
Using the new VLBA data and archival observations, they refined the distance to the binary system and found it to be farther away than previously estimated, thus raising the inferred mass of the systems black hole to 21.2 solar masses.
Over six days we observed a full orbit of the black hole and used observations taken of the same system with the same telescope array in 2011, said Professor James Miller-Jones, an astronomer at Curtin University and the International Centre for Radio Astronomy Research (ICRAR).
This method and our new measurements show the system is further away than previously thought, with a black hole thats significantly more massive.
These new observations tell us the black hole is more than 20 times the mass of our Sun a 50% increase on previous estimates, Professor Mandel said.
Using the updated measurements for the black holes mass and its distance away from Earth, we were able to confirm that Cygnus X-1 is spinning incredibly quickly very close to the speed of light and faster than any other black hole found to date, said Xueshan Zhao, a Ph.D. candidate studying at the National Astronomical Observatories of the Chinese Academy of Sciences.
The findings were published in the journal Science.
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James C.A. Miller-Jones et al. Cygnus X-1 contains a 21-solar mass black hole Implications for massive star winds. Science, published online February 18, 2021; doi: 10.1126/science.abb3363
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