Monthly Archives: July 2020

DNA/RNA Purification Kit Market 2020: Latest Analysis

Chicago, United States:- The report titled Global DNA/RNA Purification Kit Market is one of the most comprehensive and important additions to Report Hive Research archive of market research studies. It offers detailed research and analysis of key aspects of the global DNA/RNA Purification Kit market. The market analysts authoring this report have provided in-depth information on leading growth drivers, restraints, challenges, trends, and opportunities to offer a complete analysis of the global DNA/RNA Purification Kit market. Market participants can use the analysis on market dynamics to plan effective growth strategies and prepare for future challenges beforehand. Each trend of the global DNA/RNA Purification Kit market is carefully analyzed and researched about by the market analysts.

Competitive Landscape:

For studying various competitive dynamics of the Global DNA/RNA Purification Kit Market research, company profiling of key players is considered to gain overall market growth. Major market players present in the market and profiled in the report are: Thermo Fisher Scientific, Qiagen, Promega Corporation, Primerdesign, Bioneer, General Biosystems, BioFire Defense, MO BIO, Bio-Rad, Akonni Biosystems, Lucigen Corporation, Axol Bioscience, Geneaid

Download Free Sample PDF (including full TOC, Tables, and Figures) of DNA/RNA Purification Kit Market Research 2020-2026:- @

With the slowdown in world economic growth, the DNA/RNA Purification Kit industry has also suffered a certain impact, but still maintained a relatively optimistic growth, the past four years, DNA/RNA Purification Kit market size to maintain the average annual growth rate of 15 from XXX million $ in 2014 to XXX million $ in 2019, Our analysts believe that in the next few years, DNA/RNA Purification Kit market size will be further expanded, we expect that by 2024, The market size of the DNA/RNA Purification Kit will reach XXX million $.This Report covers the manufacturers data, including: shipment, price, revenue, gross profit, interview record, business distribution etc., these data help the consumer know about the competitors better. This report also covers all the regions and countries of the world, which shows a regional development status, including market size, volume and value, as well as price data.Besides, the report also covers segment data, including: type segment, industry segment, channel segment etc. cover different segment market size, both volume and value. Also cover different industries clients information, which is very important for the manufacturers.

NOTE:Due to the pandemic, we have included a special section on the Impact of COVID 19 on the DNA/RNA Purification Kit Market which would mention How the Covid-19 is Affecting the DNA/RNA Purification Kit Industry, Market Trends and Potential Opportunities in the COVID-19 Landscape, Covid-19 Impact on Key Regions and Proposal for DNA/RNA Purification Kit Players to Combat Covid-19 Impact.

Our exploration specialists acutely ascertain the significant aspects of the global DNA/RNA Purification Kit market report. It also provides an in-depth valuation in regards to the future advancements relying on the past data and present circumstance of DNA/RNA Purification Kit market situation. In this DNA/RNA Purification Kit report, we have investigated the principals, players in the market, geological regions, product type, and market end-client applications. The global DNA/RNA Purification Kit report comprises of primary and secondary data which is exemplified in the form of pie outlines, DNA/RNA Purification Kit tables, analytical figures, and reference diagrams. The DNA/RNA Purification Kit report is presented in an efficient way that involves basic dialect, basic DNA/RNA Purification Kit outline, agreements, and certain facts as per solace and comprehension.

Market Overview

The report includes detailed information about market drivers, restraints, challenges, threats, and potential growth opportunities of the Global DNA/RNA Purification Kit market. The report consists of precise qualitative information such as Porters five forces, PESTLE Analysis, and value chain analysis.

Market Segmentation:

The segmentation is used to decide the target market into smaller sections or segments like product type, application, and geographical regions to optimize marketing strategies, advertising techniques, and global as well as regional sales efforts of Global DNA/RNA Purification Kit Market. The common characters are also being considered for segmentation such as global market share, common interests, worldwide demand, and supply of Access Control devices. Moreover, the report compares the production value and growth rate of the Global DNA/RNA Purification Kit market across different geographies.

Segmentation by Application: HospitalLaboratoryClinic

Segmentation by Type: Human gDNAViral RNA/DNABacteria DNABacteria RNACell-free DNA

The Essential Content Covered in the GlobalDNA/RNA Purification Kit Market Report:

* Top Key Company Profiles.* Main Business and Rival Information* SWOT Analysis and PESTEL Analysis* Production, Sales, Revenue, Price and Gross Margin* Market Share and Size

The report provides a 6-year forecast (2020-2026) assessed based on how the DNA/RNA Purification Kit market is predicted to grow in major regions like USA, Europe, Japan, China, India, Southeast Asia, South America, South Africa, Others.

Key Questions Answered In this Report:

What is the overall market size in 2019? What will be the market growth during the forecast period i.e. 2020-2026?

Which region would have high demand for product in the upcoming years?

What are the factors driving the growth of the market?

Which sub-market will make the most significant contribution to the market?

What are the market opportunities for existing and entry-level players?

What are various long-term and short-term strategies adopted by the market players?

What are the key business strategies being adopted by new entrants in the DNA/RNA Purification Kit Market?

Get Full Customize report or for any Special Discount [emailprotected] https://www.reporthive.com/request_customization/2326303

Table of Contents

Market Overview: This is the first section of the report that includes an overview of the scope of products offered in the global DNA/RNA Purification Kit market, segments by product and application, and market size.

Market Competition by Player: Here, the report shows how the competition in the global DNA/RNA Purification Kit market is growing or decreasing based on deep analysis of market concentrate rate, competitive situations and trends, expansions, merger and acquisition deals, and other subjects. It also shows how different companies are progressing in the global DNA/RNA Purification Kit market in terms of revenue, production, sales, and market share.

Company Profiles and Sales Data: This part of the report is very important as it gives statistical as well as other types of analysis of leading manufacturers in the global DNA/RNA Purification Kit market. It assesses each and every player studied in the report on the basis of main business, gross margin, revenue, sales, price, competitors, manufacturing base, product specification, product application, and product category.

Market Status and Outlook by Region: The report studies the status and outlook of different regional markets such as Europe, North America, the MEA, Asia Pacific, and South America. All of the regional markets researched about in the report are examined based on price, gross margin, revenue, production, and sales. Here, the size and CAGR of the regional markets are also provided.

Market by Product: This section carefully analyzes all product segments of the global DNA/RNA Purification Kit market.

Market by Application: Here, various application segments of the global DNA/RNA Purification Kit market are taken into account for research study.

Market Forecast: It starts with revenue forecast and then continues with sales, sales growth rate, and revenue growth rate forecasts of the global DNA/RNA Purification Kit market. The forecasts are also provided taking into consideration product, application, and regional segments of the global DNA/RNA Purification Kit market.

Upstream Raw Materials: This section includes industrial chain analysis, manufacturing cost structure analysis, and key raw materials analysis of the global DNA/RNA Purification Kit market.

Marketing Strategy Analysis, Distributors: Here, the research study digs deep into behavior and other factors of downstream customers, distributors, development trends of marketing channels, and marketing channels such as indirect marketing and direct marketing.

Research Findings and Conclusion: This section is solely dedicated to the conclusion and findings of the research study on the global DNA/RNA Purification Kit market.

Appendix: This is the last section of the report that focuses on data sources, viz. primary and secondary sources, market breakdown and data triangulation, market size estimation, research programs and design, research approach and methodology, and the publishers disclaimer.

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Trending Now: COVID-19 impact on DNA/RNA Purification Kit Market Variables, Information, Emerging Trends, Analysis and Forecast 2020-2026 | Inovio...

Fans have been convinced all along that Khlo Kardashian has a different father than her sisters.

The third oldest Kardashian sister was born while mom Kris Jenner was still married to celebrity attorney Robert Kardashian, however she admitted to cheating on him during their relationship. This only adds fuel to the fire that Khlo could have another dad.

And theres other evidence, too. Khlo looks totally different than her sisters. Whats more, she looks a lot like a man who Kris admitted to having an affair with.

After the rumors surfaced, Khlo took a DNA test that mightdefinitively prove who her real father is.

RELATED: Khlo Kardashian Posted a Photo That Doesnt Even Look Like Her, According to Fans

Its not just that Kar-Jenner followers think Khlo has some random other dad theyve narrowed it down to Alex Roldan, Kriss hairdresser who bears a striking similarity to Khlo. Kylie even posted a photo of the two posing next to each other and joked, First official photo of my sister and her dad! Like father like daughter!

But Robert Kardashian didnt want to know if Khlo wasnthis biological child. Even if he had suspicions that she might not be relatedto him, he refused to find out for sure. He [Robert] didnt want a DNA testdone, family friend Joni Migdal said.

He didnt want to find out anything. But he knew that she [Khlo] wasnt his. His confirmation to me was, Shes mine and I dont care who the father is.

Its true that Khlo is much taller than her full sistersKourtney and Kim, which lends credibility to the claim that she could have a differentfather. But thanks to the popularity of DNA testing, there could be concreteevidence that Robert is truly Khlos real dad after all.

At first, Khlo refused her familys urging to get a DNA test. After all, her alleged biological father Robert died in 2003 and she wouldnt benefit from finding out he wasnt paternally linked to her. I dont need someone to tell me who my family is, Khlo insisted.

But then curiosity must have got the better of the36-year-old reality star. She and her sisters took a test through 23 and Methat seemingly confirmed Robert was her father all along. The results showedthat Khlo is of Middle Eastern descent just like Kim, Kourtney, and moreimportantly, their dad.

You are my sister, Kourtney said when Khlo revealed the shocking results. Oh my God, we are sisters, Khlo agreed.

With the question of her lineage cleared up, fans are morelikely to focus these days on Khlos ever-changing appearance. Old photos of theGood American collaborator show a woman thats unrecognizable compared to howshe looks recently. Besides hair extensions, fans speculate that Khlo has hadlip fillers, a nose job, cheek implants, and various other procedures.

The celeb has not confirmed any of these rumors. But she did joke with a fan who asked why she looked so different and said she had a face transfer.

Despite Khlos changing appearance, theres only one man who provided her DNA: Robert Kardashian.

Original post:
Khlo Kardashian Took a DNA Test That Probably Proves Who Her Real Father Is - Showbiz Cheat Sheet

The "Viral Vector & Plasmid DNA Manufacturing Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Product; Application, and Geography" report has been added to ResearchAndMarkets.com's offering.

The global viral vector & plasmid DNA manufacturing market is expected to reach US$ US$ 2, 247.7 million by 2027 from US$ 459.4 million in 2019. The market is estimated to grow with a CAGR of 22.1% from 2020 to 2027.

Driving factors such as growing awareness of gene therapy, increasing prevalence of genetic disorders and infectious diseases across the world are expected to upsurge the market growth. Additionally, growth in the global healthcare market is likely to have a positive impact on the market in coming years. However the high cost associated with gene therapy is the major factor hindering the market growth.

Gene therapies offer an effective way for the treatment of genetic diseases, the acceptance and awareness of gene therapy continues to grow, especially in developed regions. The increase in awareness of gene therapies leads to market entry of new and established players for manufacturing various gene therapy technologies. For instance, according to a study published by Alliance for Regenerative Medicine in 2018, the number of gene therapy-related clinical trials witnessed growth of an estimated 18.0% compared to the previous year across the world. This growth in the number of clinical trials indicates rise in awareness and massive investments.

Established companies, healthcare organizations, and research institutes are focusing on spreading awareness related to gene therapies as they offer a modern way of disease treatment. For instance, in 2018, Alliance for Regenerative Medicine announced the launch of a new foundation to promote comprehensive understanding and acceptance of gene therapies. This newly formed organization will work to grow public awareness and benefits of certain gene therapy-based aspects such as cell therapy, tissue-engineering, gene editing, and organ regeneration.

Reasons to Buy

Market Dynamics

Drivers

Restraints

Opportunities

Future Trends

Companies Mentioned

For more information about this report visit https://www.researchandmarkets.com/r/rok009

View source version on businesswire.com: https://www.businesswire.com/news/home/20200720005364/en/

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ResearchAndMarkets.comLaura Wood, Senior Press Managerpress@researchandmarkets.com For E.S.T Office Hours Call 1-917-300-0470For U.S./CAN Toll Free Call 1-800-526-8630For GMT Office Hours Call +353-1-416-8900

Original post:
Insights on the Viral Vector & Plasmid DNA Manufacturing Global Market to 2027 - by Product, Application and Geography - ResearchAndMarkets.com -...

Applied DNA reports positive preclinical results for COVID-19 vaccine

Applied DNA Sciences Inc. (APDN) announced that its COVID-19 vaccine candidate has yielded robust antibody and T-cell responses even at very low doses of linear DNA. The company is collaborating with Takis Biotech for developing this vaccine. Both the companies believe that no single vaccine may be able to offer a universal solution to the outbreak.

During the trial, BALB/c mice were given linear DNA at day 1 and a booster vaccination on day 21. All animals exhibited seroconversion to producing IgG against SARS-CoV-2 Spike Protein by day 14. There was also significant increase in response by Day 38. This data was in line with IgGs that in prior studies with plasmids were neutralizing. Five different candidates of linear synthetic genomic constructs of the S gene were assessed. These constructs were designed for optimal expression in muscle and maximal immunogenicity after vaccination.

Linear construct with the sequence corresponding to an abbreviated form of the Spike protein was found to have the strongest T-cell response to the linear vaccines. The T-cell response implicated both the CD4+ and CD8+ lineages, indicating that the response may be sustained for long term. Dr. James A. Hayward, president and CEO of Applied DNA, said, We look forward to supporting further studies by Takis with a goal of entering human trials in early Autumn. We believe no single vaccine will provide the security we need as a global population, and that our LineaDNA vaccines will complement those already marching toward the market.

Takesi CEO Dr. Luigi Aurisicchio stated that the companies need to move to toxicology studies and must undertake large animal studies. The companies are also looking to collaborate with third parties to help them in the marketing process.

As per the data retrieved from titration studies, antisera derived from mice vaccinated with linear DNA retained its binding activity even at dilutions of 1:50,000. Existence of IgGs against SARS-CoV-2 Spike in bronchoalveolar lavage shows that vaccination in mouse muscle may permit the consequent antibodies to combat the infection in the lower lung.

These vaccine candidates, in plasmid format, have shown to prompt neutralizing antibodies that blocked uptake of SARS-CoV-2 upon introducing functional virus to human cells in culture in the presence of the mouse antisera. Similar neutralization studies are planned to be undertaken shortly for the antisera produced by the linear DNA constructs.

Linear DNA vaccines have several advantages associated with them. These vaccines remain stable during storage and shipment. These are also amenable to mass production globally. There is also no risk of transferring antibiotic resistance genes. Further, these vaccines are highly efficient, are simple to produce and avoid bacterial vectors. Applied DNA stated that it is capable of manufacturing an improved LineaDNA vaccine in a short period of time of receiving the sequence of a mutant variant.

Applied DNA is a leading Polymerase Chain Reaction (PCR)-based DNA manufacturer, aiding in vitro diagnostic. The company also engages in development of pre-clinical nucleic acid-based therapeutic product candidates and supply chain security measures.

Berkeley Lights (BLI) showed stunning performance on its first day of trading. The stock opened at $51.05, 132 percent above its offer price of $22.00 apiece. The company is based out of California and described itself as leading digital-cell biology company focused on enabling and accelerating the rapid development and commercialization of biotherapeutics and other cell-based products. Berkeley proved to be the frontrunner in a bunch of biotech companies such as Relay Therapeutics (RLAY) and ALX Oncology (ALXO) raising funds this week.

Berkeley Lights offered 8.1 million shares at $22 per share. The company had raised both the quantity and price upward as earlier its offering was limited to 7.4 million shares. The estimated price range of $19 to $20 per share was also higher than its previous price target range of $16 and $18 per share.

The IPO market is currently in the boom stage in general, but the impact is particularly palpable in the biotech sector. Another biotech company, Relay Therapeutics, saw its stock shooting up 75 percent on the first of day of trading. ALX Oncology's stock climbed 58 percent, closing at $30 in comparison to its offer price of $19 per share. So far this year, 13 biotech companies have raised more than $200 million.

Berkeley does not produce any drug on its own, but its digital cell biology platform can be used to analyze living cells in a variety of ways. This feature is conducive to fast drug development and production processes. The platform captures deep phenotypic, functional and genotypic data for thousands of single cells in parallel. Digital cell biology platform mainly consists of proprietary consumables such as regent kits and OptoSelect chips.

The company is currently collaborating with Pfizer (NYSE:PFE) and Sanofi (NASDAQ:SNY) for antibody discovery processes. Berkeley Lights Beacon and Lightning systems and Culture Station instrument are designed for research use only and are not meant for use in diagnostic procedures.

Amicus Therapeutics (FOLD) reported that it has executed a definitive agreement with Hayfin Capital. The agreement will allow the company to avail up to $400 million in credit facility. Amicus plans to use the funds for financing various operational and strategic activities. The applicable interest rate for the debt is 6.5% above LIBOR, subject to a 100-basis-point floor.

Amicus stated that, subject to closing conditions, the new loan is likely to be funded before August 4, 2020. Daphne Quimi, Amicus Chief Financial Officer, said, Securing this financing with market setting terms gives us a strong financial platform to advance both patient and Amicus shareholder interests. Defining now a clear path to profitability, without the need for any future dilutive financing, reflects the global profile of Amicus today and our future. Hayfin Capital Management is a European alternative asset management firm with nearly 15 billion of assets under management.

Amicus Therapeutics is mainly engaged in the development of novel high-quality medicines for treating rare metabolic diseases. The company has robust development pipeline with well-formed focus on Fabry disease, Pompe disease and Batten disease. Amicus also has several plans in pre-clinical stage. Currently, it has Galafold monotherapy for Fabry in the market. The company expects the revenue to be in the range of $250 million to $260 million for this year.

Amicus has strong suite of platform technologies as well. Its pharmacological chaperone technology aims to deal with LDs that are characterized by mutated proteins. These pharmacological chaperones are small molecules and work by binding themselves to a target enzyme for potentially improving its stability factor. The company uses its proprietary Chaperone-Advanced Replacement Therapy (CHART) technology for developing chaperone or ERT combinations.

Thanks for reading. At the Total Pharma Tracker, we do more than follow biotech news. Using our IOMachine, our team of analysts work to be ahead of the curve.

That means that when the catalyst comes that will make or break a stock, weve positioned ourselves for success. And we share that positioning and all the analysis behind it with our members.

Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

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Applied DNA's COVID-19 Vaccine, And Other News: The Good, Bad And Ugly Of Biopharma - Seeking Alpha