The Prometheus League
Breaking News and Updates
- Abolition Of Work
- Ai
- Alt-right
- Alternative Medicine
- Antifa
- Artificial General Intelligence
- Artificial Intelligence
- Artificial Super Intelligence
- Ascension
- Astronomy
- Atheism
- Atheist
- Atlas Shrugged
- Automation
- Ayn Rand
- Bahamas
- Bankruptcy
- Basic Income Guarantee
- Big Tech
- Bitcoin
- Black Lives Matter
- Blackjack
- Boca Chica Texas
- Brexit
- Caribbean
- Casino
- Casino Affiliate
- Cbd Oil
- Censorship
- Cf
- Chess Engines
- Childfree
- Cloning
- Cloud Computing
- Conscious Evolution
- Corona Virus
- Cosmic Heaven
- Covid-19
- Cryonics
- Cryptocurrency
- Cyberpunk
- Darwinism
- Democrat
- Designer Babies
- DNA
- Donald Trump
- Eczema
- Elon Musk
- Entheogens
- Ethical Egoism
- Eugenic Concepts
- Eugenics
- Euthanasia
- Evolution
- Extropian
- Extropianism
- Extropy
- Fake News
- Federalism
- Federalist
- Fifth Amendment
- Fifth Amendment
- Financial Independence
- First Amendment
- Fiscal Freedom
- Food Supplements
- Fourth Amendment
- Fourth Amendment
- Free Speech
- Freedom
- Freedom of Speech
- Futurism
- Futurist
- Gambling
- Gene Medicine
- Genetic Engineering
- Genome
- Germ Warfare
- Golden Rule
- Government Oppression
- Hedonism
- High Seas
- History
- Hubble Telescope
- Human Genetic Engineering
- Human Genetics
- Human Immortality
- Human Longevity
- Illuminati
- Immortality
- Immortality Medicine
- Intentional Communities
- Jacinda Ardern
- Jitsi
- Jordan Peterson
- Las Vegas
- Liberal
- Libertarian
- Libertarianism
- Liberty
- Life Extension
- Macau
- Marie Byrd Land
- Mars
- Mars Colonization
- Mars Colony
- Memetics
- Micronations
- Mind Uploading
- Minerva Reefs
- Modern Satanism
- Moon Colonization
- Nanotech
- National Vanguard
- NATO
- Neo-eugenics
- Neurohacking
- Neurotechnology
- New Utopia
- New Zealand
- Nihilism
- Nootropics
- NSA
- Oceania
- Offshore
- Olympics
- Online Casino
- Online Gambling
- Pantheism
- Personal Empowerment
- Poker
- Political Correctness
- Politically Incorrect
- Polygamy
- Populism
- Post Human
- Post Humanism
- Posthuman
- Posthumanism
- Private Islands
- Progress
- Proud Boys
- Psoriasis
- Psychedelics
- Putin
- Quantum Computing
- Quantum Physics
- Rationalism
- Republican
- Resource Based Economy
- Robotics
- Rockall
- Ron Paul
- Roulette
- Russia
- Sealand
- Seasteading
- Second Amendment
- Second Amendment
- Seychelles
- Singularitarianism
- Singularity
- Socio-economic Collapse
- Space Exploration
- Space Station
- Space Travel
- Spacex
- Sports Betting
- Sportsbook
- Superintelligence
- Survivalism
- Talmud
- Technology
- Teilhard De Charden
- Terraforming Mars
- The Singularity
- Tms
- Tor Browser
- Trance
- Transhuman
- Transhuman News
- Transhumanism
- Transhumanist
- Transtopian
- Transtopianism
- Ukraine
- Uncategorized
- Vaping
- Victimless Crimes
- Virtual Reality
- Wage Slavery
- War On Drugs
- Waveland
- Ww3
- Yahoo
- Zeitgeist Movement
-
Prometheism
-
Forbidden Fruit
-
The Evolutionary Perspective
Monthly Archives: August 2017
Missouri governor stays execution of Marcellus Williams, says officials will probe DNA evidence in the case – Washington Post
Posted: August 25, 2017 at 3:40 am
Hours before convicted killer Marcellus Williams was scheduled to die by lethal injection, Missouri's governor has halted his execution. His attorneys argued that recent DNA evidence shows he is innocent in the killing of a former newspaper reporter. (Reuters)
Missouri Gov. Eric Greitens (R) on Tuesday stayed the scheduled execution ofMarcellus Williams, just hours before the death-row inmate was set to be put to death for the 1998 killing of a former newspaper reporter.
Williamss looming lethal injection prompted scrutiny and a last-ditch appeal to the U.S. Supreme Court from his attorneys, who pointed to new DNA evidence in arguing that Missouri may have been on the verge of executingthe wrong person.
Greitens said he would appoint a board to look into the new DNA evidence and other factors before issuing a report about whether or not Williams should be granted clemency.
A sentence of death is the ultimate, permanent punishment, Greitens said in a statement. To carry out the death penalty, the people of Missouri must have confidence in the judgment of guilt.
[Earlier this year, Arkansas executed four inmates in eight days]
Williams, 48, was convicted in 2001 of brutally killing Felicia Lisha Gayle, who had been a reporter with the St. Louis Post-Dispatch. Gayle was in her home when she was stabbed 43 times with a butcher knife, according to court records.
Williams was scheduled to be executed in 2015 for the high-profile killing, but the state Supreme Court stayed his lethal injection, allowing him time to obtain the new DNA testing.
Attorneys for Williams have arguedhe is innocent, pointing to DNA tests they say producedconclusive scientific evidence that another man committed this crime. They say this evidence shows that DNA belonging to someone else was found on the murder weapon, exonerating Williams.
Theyre never going to ever confront an actual innocence cause more persuading than this involving exonerating DNA evidence, said Kent Gipson, one of Williamss attorneys. Ive seen a lot of miscarriages of justice, but this one would take the cake.
State officials, though, said they still believed Williams is guilty because ofother compelling non-DNA evidence.
[Johnson & Johnson says its drug shouldnt be used in executions]
In court filings, the office of Joshua D. Hawley, Missouris attorney general, listed some of these other factors, describing two people a man who served time with Williams and Williamss girlfriend who both told police that he confessed to the killing. Williams had also sold a laptop stolen from Gayles home, Hawleys office wrote in the filings, and items belonging to Gayle were found in a car Williams drove the day she was killed.
Based on the other, non-DNA, evidence in this case, our office is confident in Marcellus Williams guilt and plans to move forward, Loree Anne Paradise, Hawleys deputy chief of staff, wrote in an email Tuesday.
After Williamss execution was stayed, Paradise said her office was still confident in what the jury determined in 2001.
We remain confident in the judgment of the jury and the many courts that have carefully reviewed Mr. Williams case over sixteen years, she wrote Tuesday afternoon. We applaud the work of the numerous law enforcement officers who have dedicated their time and effort to pursuing justice in this case.
Attorneys for Williams and state officials had both made their arguments to Supreme Court Justice Neil M. Gorsuch, who is assigned cases from the federal circuit covering Missouri. Neither Gorsuch nor the full court had publicly weighed in before Greitens halted the scheduled execution.
[Pfizer tightens restrictions to keep drugs from being used in executions]
Alittle more than four hours before Williams was set to be executed,Greitens signed an executive orderhalting the lethal injection. Greitens alsoappointed a board of inquiry to further consider Williamss clemency request and issue a report about whether he should be executed or have his sentence commuted.
In his statement,Greitens said he was appointing the board in light of new information.According to Greitenss executive order, the board will consider newly discovered DNA evidence as well as any other relevant evidence not available to the jury.
The controversy surrounding Williamss scheduled lethal injection had drawn unusual attention to what would be a relatively rare execution in the United States, where the death penalty has been declining for years.
There have been 16 people executed so far this year in the United States, one of them in Missouri, which is among a handful of states still regularly executing inmates. Last year, there were 20 executions in the United States, the fewest in 25 years. That number is expected to increase slightly this year, but 2017 will still see one of the lowest annual number of executions than most years since 1990.
[Why the U.S. could see more executions this year]
Death sentences have become less common nationwide, dropping from 315 such sentences in 1996 to 31 last year, according to the Death Penalty Information Center, a Washington-based group that tracks capital punishment. Public support for the death penalty has also fallen over the same period. In a Pew Research Center survey last year, American support for capital punishment fell below 50 percent for the first time since Richard Nixon was president. A Gallup poll, also conducted last year, found support remained at 60 percent. In both cases, the numbers represented a sharp drop from the mid-1990s, when 4 in 5 Americans backed the death penalty.
While some states have abandoned capital punishment or been unable to carry out executions amid an ongoing drug shortage, Missouri has been an outlier. Missouri is one of three states, along with Texas and Georgia, to execute at least one inmate each year since 2013.
In 2015, when Missouri last intended to execute Williams, the states Supreme Court stayed the lethal injection. A laboratory tested evidence from the scene of Gayles killing and a DNA expert determined that Williams could not have contributed to the DNA found on the knife that killed the former reporter, Williamss attorneys said.Last week, theMissouri Supreme Courtrejected a request to stay Williamss execution without explanation.
Missouri officials had argued in court that in order to exonerate Williams, DNA evidence would have to explain how Williams ended up with the victims property, and why two witnesses independently said he confessed to them, or at least provide a viable alternate suspect. They also said that just showing unknown DNA on the knife handle does not alone prove Williamss innocence.
The item was a kitchen knife with both male and female DNA on the handle, Hawleys office wrote in a filing to the Supreme Court. It is reasonable to assume people not involved in the murder handled the knife in the kitchen. And there is no reason to believe Williams would not have worn gloves during a burglary and murder, as he wore a jacket to conceal his bloody shirt after he left the murder scene.
[Ohio executes Ronald Phillips, resuming lethal injections after three-year break]
Gipson argued that the case against Williams was always weak, consisting primarily of the statements of two jailhouse informants who claimed Williams had confessed to the crime. Gipson also said that bloody footprints at the scene did not match Williamss shoe size and added that bloody fingerprints were never tested or compared to Williamss fingerprints because they were lost by police.
The DNA testing, which Williamss attorneys said was enabled by advances in technology, formed the main argument they made in appealing to the U.S. Supreme Court.
A DNA profile was developed from the handle of the knife that was found in the victims body and that does not match the DNA of Marcellus, Gipson said Tuesday, adding that three separate experts have concluded that the DNA left on the knife and at the scene was a match for another man and not Williams. Its clear that the DNA on the knife is the DNA of the killer. Each expert has concluded that you can scientifically exclude Marcellus as the contributor of the DNA on the knife.
Civil rights groups also weighed in on the case, both due to Williamss claims ofinnocence as well as racial undertones in the prosecution of a black man charged with killing a white woman.
The Supreme Court has emphasized over and over that because death is a unique punishment there is need for heightened reliability before its imposed, said Sam Spital, director of litigation for the NAACP Legal Defense Fund, which is not directly involved in Williamss case. One of the really significant questions raised by Mr. Williamss case is, what does it mean when you have issues of innocence?
Like Williamss attorneys, Spital noted the lack of forensic evidence linking Williams to the crime as well as the new DNA evidence. Spital also pointed to another concern, echoing attorneys for Williams, who described the case as racially charged. Spital said six of the seven potential black jurors in the case were struck from the jury pool in one case because the potential juror looked like Williams.
This execution has to be stayed so these substantial questions of innocence can be considered, in addition to some real concerns about race discrimination, Spital said before the governor had issued the stay.
This story has been updated since it was first published.
Read more:
Arkansas planned an unprecedented wave of executions because its lethal drugs were about to expire
The steady decline of Americas death rows
An Arkansas death row inmate took their fathers life. Heres why they dont want the killer executed.
Drug companies take aim at executions and demand their drugs back
Ohios youngest death row inmate never touched the murder weapon. Why was he sentenced to death?
Go here to see the original:
Missouri governor stays execution of Marcellus Williams, says officials will probe DNA evidence in the case - Washington Post
Posted in DNA
Comments Off on Missouri governor stays execution of Marcellus Williams, says officials will probe DNA evidence in the case – Washington Post
Danish police: DNA from dismembered body matches missing journalist – CNN
Posted: at 3:40 am
At a press conference, chief investigator Jens Mller Jensen said police had linked the victim to the torso with DNA obtained from her toothbrush and hairbrush. Blood found on the submarine was also a match for Wall, he said.
Mller Jensen said the body had apparently been punctured to let the air out before sinking it, and it was weighted down in a presumed attempt to prevent it floating.
Wall, 30, had boarded a 17-meter, privately built submarine on August 10 for a story she was writing about its inventor, Peter Madsen.
She was last seen on that day in an image that allegedly showed her standing with Madsen in the tower of the submarine in Copenhagen Harbor.
A passing cyclist found the torso Monday afternoon on the southwest side of Amager island near the Danish capital.
Police had earlier said the body appeared to have been deliberately dismembered.
"Naturally, the DNA match is a relatively large breakthrough in the investigation which will now continue until we have built all possible information in the case," said Mller Jensen.
Investigators and divers are carrying out an extensive search Wednesday for "remaining body parts and clothing" in coastal areas of Amager island, he said.
In a statement posted to Facebook, Wall's mother, Ingrid Wall, spoke of the family's "immense grief and shock" on learning that the journalist's remains had been found, and said many questions remained unanswered.
She recalled the impact of her daughter's disappearance on her family, friends and colleagues around the world, as well as the powerful stories she had told from remote corners of the planet.
"Following Kim's disappearance, we have received countless messages about how loved and appreciated she was -- as a human being, as a friend and as a journalist. It's a true testament to the impact she's had on others," she said.
"She gave a voice to weak, vulnerable and marginalized people. It's a voice this world needed for years to come, but that has now been silenced."
Madsen, who has been charged with manslaughter, told a closed-door court hearing Monday that Wall had died in an accident and was buried at sea in an "unspecified place" in Kge Bay, according to a statement.
Madsen, 46, originally claimed he had dropped her off on land on the night of August 10, according to a police statement.
But police later said Madsen had provided them with a "different explanation."
The inventor was charged with manslaughter on August 11 and ordered to be held in custody for 24 days.
His lawyer Betina Hald Engmark told Denmark's TV2 at the time that her client "accepts the arrest but still denies the crime."
According to CNN's Swedish affiliate Expressen, the submarine -- which had sunk -- was found at 10:30 a.m. on Friday, August 11, 15 hours after it had departed Copenhagen.
Police said there was no trace of Wall when the submarine was found by emergency services.
Expressen reporter Federico Moreno, speaking to CNN from Amager island near where the torso was found, said the search effort appeared to have intensified since Tuesday.
He said he could see about 10 divers searching the waters off the island, more than double the number he'd seen a day earlier. The spot where the torso was found is also not far from the location where the submarine sank, he said.
Danes with whom Moreno has spoken about the case say the circumstances are very strange and that they have questions about Madsen's changing accounts of what happened, he said.
Moreno said that Madsen's lawyer, Hald Engmark, had sent him a text message after Wednesday's police press briefing to say that Madsen maintained his innocence.
Madsen was already famous in Denmark before his name hit the headlines in relation to this case, Moreno said. He had launched his submarine, the UC3 Nautilus, in 2008 with the help of crowdfunding.
Wall wasn't a household name in Sweden, in part because she mostly wrote for English-language publications, Moreno said, but she was an experienced reporter and her family is well known in media circles.
Wall, a graduate of Columbia University and London School of Economics, was based between Beijing and New York. Her work appeared in the New York Times, the Guardian and TIME among others.
Her father was a photojournalist for Expressen for many years and her brother also works as a photojournalist for Swedish publications, Moreno said.
CNN's James Masters, Jim Stenman, Sophia Chalmer, Hilary McGann and Henrik Pettersson contributed to this report.
Read more here:
Danish police: DNA from dismembered body matches missing journalist - CNN
Posted in DNA
Comments Off on Danish police: DNA from dismembered body matches missing journalist – CNN
Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion – Arizona Public Media
Posted: at 3:39 am
Over millions of years, the Arizona bark scorpion has evolved into a true desert survivor.
Now, new research traces its origins to an abrupt and massive genetic event.
More than 450 million years ago, the entire genetic instruction book of spiders' and scorpions' common ancestor doubled, according to a genomic comparison of the common house spider (Parasteatoda tepidariorum) and the Arizona bark scorpion (Centruroides sculpturatus).
Kim Worley of Baylor College of Medicine, who worked on the BMC Biology study, said gene replicas help species diverge by freeing up copies for other uses.
"One copy can continue to provide the functions that it was used for originally, and the new copy is not constrained to provide those functions because the original copy's already providing it," Worley said.
Whole genome duplication is not unheard of. Copies of single genes or chromosomes are more common.
"Genomes change over time, often because of this duplication and divergent process. And sometimes that's individual genes or parts of genes, and sometimes that's larger regions parts of chromosomes, or even whole chromosomes, or even whole genomes in some cases," Worley said.
Most duplicate genes are later lost; those that remain can take on new roles.
The gene sequencing took place as part of a pilot study for i5k, a project that aims to sequence 5,000 arthropod genomes.
Read more:
Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion - Arizona Public Media
Posted in Genome
Comments Off on Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion – Arizona Public Media
Whole genome sequencing now being used to reduce food poisoning outbreaks in NSW – The Sydney Morning Herald
Posted: at 3:39 am
Food-borne illnesses caused by bugs such as salmonella could be cut by a third in NSW within five years, with food and health authorities adding a "revolutionary" tool to their arsenal.
NSW Health and NSW Food Authority have started using whole genome sequencing technology to more quickly identify a food-borne outbreak and connect it with its source, which could reduce illnesses and even deaths.
Play Video Don't Play
Play Video Don't Play
Previous slide Next slide
Norovirus causes gastroenteritis in around two million Australians every year. Here's how to avoid getting it, or passing it on.
Play Video Don't Play
After years of denials, the former PM reveals he missed a vote in Parliament in 2009 because he passed out after drinking too much.
Play Video Don't Play
From the 1930s to now, see how Botany has transformed.
Play Video Don't Play
The Queensland government plans to implement all 58 recommendations of an audit following the Dreamworld theme park ride accident last year.
Play Video Don't Play
Officers from the QPS LGBTI Liaison Program each have messages of advice and encouragement for the LGBTI community on Wear It Purple Day.
Play Video Don't Play
It has been revealed that William Tyrrell was in foster care at the time of his disappearance three years ago. Vision: Seven News.
Play Video Don't Play
The One Nation senator concedes he didnt renounce his British citizenship until after nominating for parliament.
Play Video Don't Play
An anti-vax doctor speaks out after being exposed as one of a group of Melbourne GPs under investigation after a video was made public claiming doctors have helped hundreds of families avoid vaccines.
Norovirus causes gastroenteritis in around two million Australians every year. Here's how to avoid getting it, or passing it on.
"[It's] a significant breakthrough that could help revolutionise how food-borne illnesses are identified, understood, tracked and managed," said Dr Craig Shadbolt, the Food Authority's acting chief executive.
"This will be invaluable in terms of achieving the NSW Government's Food Safety Strategy goal of reducing food-borne illnesses caused by salmonella, campylobacter and listeria by 30 per cent by 2021."
A growing number of disease control agencies around the world are using whole genome sequencing, which reveals the complete DNA make-up of an organism, to contain and control outbreaks.
In Australia, rates of food-borne salmonella poisoning have climbed from 38 per 100,000 people in 2004 to 76 per 100,000 in 2016, with a record-breaking 18,170 cases last year, according to the National Notifiable Diseases Surveillance System.
Dr Shadbolt said whole genome sequencing allowed their investigators to see the genetic sequence of a bacteria, for example, in infected patients and match it to bacteria found during an investigation.
Get the latest news and updates emailed straight to your inbox.
He said any delay in being able to definitively identify the cause of an outbreak increased the chances of more people becoming ill.
"Prior to the adoption of whole genome sequencing, which is the most significant advancement in this field in a generation, we were unable to confirm related cases as quickly as we can now," he said.
"Where in the past cases may have appeared random and unrelated we now have the ability to see the genetic sequence of bacteria found in infected patients and match them, allowing us to more quickly connect an outbreak back to its source."
The technology was first used in 2015 after 37 people became infected with a rare form of salmonellosis Salmonella Agona in Western Sydney.
Using traditional methods, the investigators concluded a tuna sushi product at a particular sushi shop was to blame and the shop was ordered to stop selling the product.
However, whole genome sequencing of several samples revealed the first cases occurred earlier than thought and the source may have been raw chicken meat, which was supplied to two sushi shops in the one shopping centre.
Since then, the tool has been further refined and used in the salmonella outbreak linked to rockmelons and a multi-jurisdictional outbreak of listeriosis last year.
NSW Health's communicable diseases director Dr Vicky Sheppeard said the technology was part of a two-year trial, and they would compare the cost and timeliness of new and existing methods.
"It did take a little time to ramp up but over the past couple of months the timelines has been getting quite similar to our existing methods and the increased sensitivity has allowed us to find outbreaks that we weren't finding before," she said.
Dr Sheppeard said one of the challenges was the large amounts of data processing and storage required.
"Our 2016 annual report is just about to go up and we have seen a downturn in salmonella in NSW, so we are seeing promising early signs the actions that have been implemented are showing results," she said.
Minister for Primary Industries Niall Blair said the results so far were "exciting".
"The use of this technology essentially means we are now looking at organisms with a microscope now instead of a magnifying glass," he said.
"The adoption of this technology will help reduce future outbreaks because we can see more, act faster and control them better."
Read this article:
Whole genome sequencing now being used to reduce food poisoning outbreaks in NSW - The Sydney Morning Herald
Posted in Genome
Comments Off on Whole genome sequencing now being used to reduce food poisoning outbreaks in NSW – The Sydney Morning Herald
Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives – Journal of Virology
Posted: at 3:39 am
Virus infection of humans and livestock can be devastating for individuals and populations, sometimes resulting in large economic and societal impact. Prevention of virus disease by vaccination or antiviral agents is difficult to achieve. A notable exception was the eradication of human smallpox by vaccination over 30 years ago. Today, humans and animals remain susceptible to poxvirus infections, including zoonotic poxvirus transmission. Here we identified a small molecule, bisbenzimide (bisbenzimidazole), and its derivatives as potent agents against prototypic poxvirus infection in cell culture. We show that bisbenzimide derivatives, which preferentially bind the minor groove of double-stranded DNA, inhibit vaccinia virus infection by blocking viral DNA replication and abrogating postreplicative intermediate and late gene transcription. The bisbenzimide derivatives are potent against vaccinia virus and other poxviruses but ineffective against a range of other DNA and RNA viruses. The bisbenzimide derivatives are the first inhibitors of their class, which appear to directly target the viral genome without affecting cell viability.
IMPORTANCE Smallpox was one of the most devastating diseases in human history until it was eradicated by a worldwide vaccination campaign. Due to discontinuation of routine vaccination more than 30 years ago, the majority of today's human population remains susceptible to infection with poxviruses. Here we present a family of bisbenzimide (bisbenzimidazole) derivatives, known as Hoechst nuclear stains, with high potency against poxvirus infection. Results from a variety of assays used to dissect the poxvirus life cycle demonstrate that bisbenzimides inhibit viral gene expression and genome replication. These findings can lead to the development of novel antiviral drugs that target viral genomes and block viral replication.
A.Y. and M.H. contributed equally to this article.
Citation Yakimovich A, Huttunen M, Zehnder B, Coulter LJ, Gould V, Schneider C, Kopf M, McInnes CJ, Greber UF, Mercer J. 2017. Inhibition of poxvirus gene expression and genome replication by bisbenzimide derivatives. J Virol 91:e00838-17. https://doi.org/10.1128/JVI.00838-17.
Read the original post:
Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives - Journal of Virology
Posted in Genome
Comments Off on Inhibition of Poxvirus Gene Expression and Genome Replication by Bisbenzimide Derivatives – Journal of Virology
Genome cloaking can protect patient privacy, Stanford researchers say – Healthcare IT News
Posted: at 3:39 am
Researchers from Stanford University have a developed a method dubbed genome cloaking, which keeps a patients private genetic information protected when doctors analyze complete human genomes.
The method uses cryptography to hide almost 99 percent of genetic information, while allowing researchers to access specific gene mutations, according to the study. Now researchers can scour complete genomes -- without seeing any genetic information irrelevant to the inquiry.
The cloaking technique could alleviate privacy and potential discrimination concerns when it comes to genomic sequencing.
[Join Your Peers at HIMSS Healthcare Security Forum! Register Today]
We now have the tools in hand to make certain that genomic discrimination doesnt happen, Gill Bejerano associate professor of developmental biology, of pediatrics and of computer science at Stanford said in a statement.
There are ways to simultaneously share and protect this information, he added. Now we can perform powerful genetic analyses while also completely protecting our participants privacy.
The genome cloaking approach lets patients encrypt their genetic data using an algorithm on their computer or smart device. The researchers said the information is uploaded into the cloud, where researchers use a multi-party computation to analyze the data and reveal only the necessary gene variants relevant to the investigation.
This means that no one has access to the complete set of genetic data other than the patient, Bejerano explained.
The researchers hope that this method -- if routinely implemented -- could help patients overcome access concerns that may be preventing them from sharing their genomic data. Many patients are concerned about how their genomic sequence could be used against them -- like in obtaining insurance.
Often people who have diseases, or those who know that a particular genetic disease runs in their family, are the most reluctant to share their genomic information because they know it could potentially be used against them in some way, Bejerano said.
They are missing out on helping themselves and others by allowing researchers and clinicians to learn from their DNA sequences.
Twitter:@JessieFDavis Email the writer: jessica.davis@himssmedia.com
View post:
Genome cloaking can protect patient privacy, Stanford researchers say - Healthcare IT News
Posted in Genome
Comments Off on Genome cloaking can protect patient privacy, Stanford researchers say – Healthcare IT News
Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion – KJZZ
Posted: at 3:39 am
KJZZ | Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion KJZZ Over millions of years, the Arizona bark scorpion has evolved into a true desert survivor.Now, new research traces its origins to an abrupt and massive genetic ... |
Here is the original post:
Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion - KJZZ
Posted in Genome
Comments Off on Rare Whole Genome Duplication Gave Rise To Arizona Bark Scorpion – KJZZ
Living to 125 Too Much of a Good Thing? – Pike County News Watchman
Posted: at 3:38 am
A 125-year life expectancy for human beings? I have zero desire to stick around that long.
Ah, yes, you speak of a debate among scientists over human longevity. I read about it at Business Insider. Some scientists argue that the maximum age humans may live is 115 years, whereas others argue that 125 years is possible.
A hundred and twenty-five years of watching Republicans and Democrats going at it? The heck with that.
Living is rife with challenges, to be sure. But living a long life has its upsides. Wouldnt you want to visit your parents and other family members for a lot more years than most of us are able? Wouldnt you like to see them all at a Sunday dinner several more times than most human beings are able?
Maybe with your family. My family has taken years off of my life!
I see, but wouldnt it be awesome if some of our finest human beings could stick around longer? Don Rickles, one of the greatest entertainers ever, died this year at 91. How great would it be to keep him around for two more decades?
True, but if Rickles were to stick around longer, that means annoying celebrities would stick around, too, and keep yapping at us every time a Republican becomes president.
There are other upsides to a longer life. What if we could keep our greatest minds around longer? Where would the world be if Einstein had another 25 years to unlock the mysteries of the universe?
But what if he figured out ways to extend human life even further, which would require me and the wife to have to keep coming up with new things to bicker about? Who has that kind of energy?
The downsides are a fair point. As people live longer, they could overburden government programs, such as Social Security. Where would we get all the money to support them?
How about we especially extend the lives of the rich so we can take them to the cleaners?
And living is expensive. If you live to 125, how will you pay for your housing and food and everyday expenses?
Thank goodness McDonalds is always hiring, but I for one have no desire to flip burgers at the age of 125.
The costs of medical care are too high for millions now. I imagine that at 125 years of age, ones medical bills would be difficult to manage.
Look, as a middle-aged guy, who is already showing signs of fatigue, here is what I know about living. Life is largely made up of colds, bills, speeding tickets and people who let you down. These experiences are connected together by a series of mundane tasks.
Did anyone tell you how cheerful you can be? Go on.
Well, these drudgeries are occasionally interrupted by a wonderful meal, a really good laugh with friends or a romantic evening with a lovely woman. Then the mundane stuff starts all over again. Who wants 125 years of that?
A lot of people do. The human lifespan has improved significantly in the past few generations. Millions are living healthy lives beyond the age of 80 today, and, when they were younger, few of them expected to live that long. Why not live relatively good lives until 125?
Because then Id really worry about my slacker son.
Why?
Hes 35 years old and still living at home. If we drastically extend lifespans, my wife will have to tell him: Son, youre 100 years old! When are you going to move out of the basement and get a job?
Follow this link:
Living to 125 Too Much of a Good Thing? - Pike County News Watchman
Posted in Human Longevity
Comments Off on Living to 125 Too Much of a Good Thing? – Pike County News Watchman
US obsession with electronics has huge human price – In Motion
Posted: at 3:38 am
By Austin Lombard Special to In Motion
My cellphone. Its so much more than just a device.
I use it to call people. I use it to navigate in the car. I use it to look up recipes in the kitchen. I use it as my shopping list in the grocery store. I use it to read the news.
Smartphones like mine and electronics like the computer Im using to write this are so ubiquitous in modern lives that few question where they come from or where they go. Electronics are so essential to civilization that we take them for granted.
But the amount of resources that go into making these devices is staggering. Manufacturing a single computer and monitor requires at least 530 pounds of fossil fuels, 50 pounds of chemicals and 3,000 pounds of water. The U.S. Environmental Protection Agency also lists copper, silver, gold and palladium as just a few of the valuable metals contained in our electronics.
Even so, the cost of sourcing and manufacturing electronics cannot strictly be measured in mineral resources. All along the supply chain and manufacturing, human labor is required to make them possible. Over the last decade, the ethical implications of sourcing and manufacturing electronics has come into sharp scrutiny, particularly because of its contrast with the exorbitant wealth the industry brings to the engineers living in technology-driven economies in cities like Cupertino, Calif. and Bellevue, Wash.
Electronics dirty secret
In 2010, manufacturing giant Foxconn experienced a rash of suicides at its Shenzhen campuses in China, prompting the company to install nets around the manufacturing plant to prevent employees from taking their own lives. The New York Times reported that one 19-year-old victim there worked over three times the legal limit of overtime in the month before his death. In 2015, Reuters news agency reported that South Korean electronics company Samsung agreed to create an $86 million fund to compensate workers who contracted cancer working with hazardous materials at its manufacturing facilities.
Sourcing materials can come at a heavy human cost. Awareness of conflict or blood diamonds hit the U.S. mainstreams attention when Kanye West released his song Diamonds from Sierra Leone in 2005. The music video contrasted images of wealthy Europeans and himself wearing diamonds, with images of child slaves mining those diamonds under the watch of armed rebel guards.
What didnt gain as much attention, however, were other valuable metals with less shine: minerals like copper and cobalt. The United Nations Office on Drugs and Crimes 2011 report on Organized Crime and Instability in Central Africa cited those two minerals as a serious source of funding for organized crime in the Democratic Republic of the Congo. Most of us probably own less diamonds than Kanye, but we all have a cell phone.
News reports have prompted electronics industry leaders such as Intel and Apple to establish initiatives to audit their supply chains and manufacturing sites for human rights violations. While a step in the right direction, these measures are not a complete solution. Even Intels 2017 Conflict Minerals White Paper a corporate communication detailing its efforts to eliminate conflict minerals from its supply chain admits that Conflict-free sourcing is not fully resolved, even after a decade of diligence. To this day, manufacturing sites draw controversy. Yet, other electronics companies have not bothered to establish official missions to eliminate human rights abuses from supply chains and manufacturing processes.
E-wastelands overseas
Our problems with electronics, unfortunately, do not end at manufacturing. The most difficult problem of all lies in the disposal of obsolete or broken electronics, or e-waste. E-waste from printers, monitors, computers and phones contains high levels of toxins, such as lead, mercury and cadmium. Because these toxins can seep out of e-waste and contaminate water sources, it is illegal to send them to landfill in the United States. Because of this, all government agencies urge consumers to recycle used electronics. But thats the problem
The Basel Action Network and Massachusetts Institute of Technology worked in partnership to conduct a study: GPS devices were attached to discarded electronics and given to certified recyclers. In the Basel Action Networks press release, it was reported that about 40 percent of the deliveries were exported, mostly to China. Recycling operations in developing countries are typically carried out by people living in abject poverty, using practices that disregard the safety of the laborers and the environment because they are unaware of the dangers the materials pose.
Yuan Chun Li and Banci Lians book, E-waste: Management, Types, and Challenges, describes approximately 1.6 million tons of e-waste sent to the junkyard town of Guiyu annually. The air there is thick with lead fumes from de-soldering operations, plastics and flame retardant chemicals are burned in the open with no breathing protection, and runoff from gold reclamation makes water so acidic that merely touching it will burn your skin. Children are stillborn or born with defects at a high rate. Farming villages are transformed into toxic wastelands.
Sustainability key to success
So if recycling is a poor option, what can we do? Some of you might be familiar with the three Rs of sustainability: Reduce, Reuse, Recycle. These three Rs are listed in order of importance. We need to look at reducing the amount of electronic waste we generate. We can start to do this by taking care of our electronics and by repairing and upgrading devices. When a part breaks or becomes obsolete, we should replace only that part, rather than throwing the entire device away and buying a new one. IFixIt.com is a wiki-styled website with user-contributed repair guides, as well as staff teardowns and reviews that rate devices on the ease with which they can be repaired. New enterprises like Fairphone put human rights, repairability and device longevity first. The first stirrings of change are in the air, if you know where to look.
The ugly burden of our digital age is a complicated problem. Fully solving it requires electronics corporations to change the way they do business. Environmental regulations must be created and enforced to prevent unscrupulous dumping of toxic waste on the impoverished people of our world. Ultimately, laymans attitudes on electronics need to shift to sustainability, using a device until it cannot be repaired, rather than upgrading every time a new device comes out on the market.
For most of us these requirements may seem out of our hands. But by choosing products built for repairability and longevity, ordinary people can influence the market to produce sustainable products. As business strategist and sustainability expert Brian Moore states in his book, IT Sustainability for Business Advantage, one of the biggest factors in promoting sustainability within business is simply that it matters to stakeholders and consumers.
Only when consumers, shareholders, and voting citizens like us begin to refuse to ignore the blood and lead staining our hands, will business and government follow suit.
. Bookmark the
.
Visit link:
US obsession with electronics has huge human price - In Motion
Posted in Human Longevity
Comments Off on US obsession with electronics has huge human price – In Motion
Graphic pictures reveal the horror of eczema sufferer ‘skinned alive … – The Sun
Posted: at 3:38 am
ANartist suffered withdrawal symptoms that left her looking like a burns victim and in too much pain to wear clothes after becoming addicted to steroid cream for eczema.
Juli-Anne Coward has spent decades battling topical steroid cream withdrawal (TSW), also known as red skin syndrome, which has caused agonising flare-ups, sore, cracked and peeling skin every time she tried to wean herself off the creams.
PA Real Life
PA Real Life
At its worst Juli-Anne, from Leominster in Herefordshire, said her entire body was covered in raw patches and oozing boils.
But now she has weaned herself off the creams for good.
She said: The longer I am without them, the better I become.
Im definitely seeing progress. I managed a four-mile walk the other day, which is something I havent done in years.
When I first came off them, my body went through hell but I finally feel like Ive turned a corner.
Juli-Anne, 50, was first diagnosed with eczema when she was just three months old and was prescribed a topical steroid cream to calm her itchy skin.
PA Real Life
Throughout her childhood she was plagued by illness and when she was nine had an allergic reaction to penicillin which caused a build-up of fluid in her lungs.
Medics prescribed a six-month course of cortisoneinjections a type of steroid hormone to help her regain her strength but as soon as they stopped her skin went completely haywire.
My eczema went absolutely crazy, and I developed the worst acne youve ever seen, she recalled.
The spots were almost like boils far beyond typical teenage blemishes. Theyd crack and bleed.
I had one on my leg which was so painful, I couldnt even put my foot down.
My confidence was absolutely gone. I hated PE at school, hated showing off my legs. I missed out on a lot.
PA Real Life
PA Real Life
By the time she reached her 20s, Juli-Anne was using a low dose steroid cream every day.
It cleared her skin and, slowly, her self-esteem began to improve.
But if she ran out, or forgot to apply it, her skin would flare up again.
She said: I lived in fear of running out of cream. I could never go anywhere impromptu just in case.
It almost felt like an addiction. If I didnt apply it, my skin would start to burn.
The only way I can describe it to people is that it feels like my clothes are made of nettles and full of wasps.
In her 30s Juli-Anne had a particularly bad reaction after doctors suggested she try a cream commonly used to treat scabies.
Her skin began to shed, peel and bleed, to the point where it was too painful to even wear clothes, leaving her housebound.
PA Real Life
PA Real Life
PA Real Life
Over the next few years Juli-Anne saw various doctors but none seemed to be able to offer a permanent solution to her problem.
In 2016 she decided to research her problem online and came across an online support group called ITSAN the international topical steroid addiction network.
Reading through posts, she became convinced that she, too, was suffering from the condition.
She recalled: It was really emotional. I sobbed and sobbed, because I couldnt believe this was happening to me.
I was terrified at the prospect of what was to come, too, but I knew I had to come off the creams to stop this once and for all.
Red Skin Syndrome, also known as Topical Steroid Addiction or Topical Steroid Withdrawal, is a condition that can arise from the use of topical steroids to treat a skin problem, such as eczema.
RSScan also arise from topical steroid use in individuals with no prior skin condition; such as with cosmetic use for skin bleaching or to treat acne, or in the case of caregivers who neglect to wash their hands after applying topical steroids on someone else.
RSS is characterised by red, itchy, burning skin that can appear after ceasing topical steroid treatments, or even between treatments.
Symptoms:
These can fall into two categories - those that appear while using creams and those that appear when not.
Treatment:
In order to treat the condition, the use of steroid creams must be stopped.
The condition resolves over time, but no medications or methods of treatment have been proven to speed up the healing process.
Source: Itsan - the red skin syndrome support group
After slowly lowering her dose, Juli-Anne stopped using steroid creams for good in September 2016.
At first her skin was in agony but over time she slowly began to improve.
Juli-Anne still wears her clothes inside out so the seams dont irritate her and wraps her skin in bandages every day to protect it.
But she sheds far less than she used to and her skin does not weep as much.
PA Real Life
Juli-Anne, who has been with her partner Carolyn, 54, for 20 years, also uses gentle, natural products on her skin instead of soaps that can be harsh on skin conditions like eczema.
Around two weeks ago she was also told by doctors that her health woes have caused osteoporosis, so shes taking calcium and vitamin D to help protect her bones.
She said: I want to say to others that I understand coming off steroid creams is scary, but support is out there.
Arm yourself with as much knowledge as you can, listen to your body and do whats right for you and your skin.
We pay for your stories! Do you have a story for The Sun Online news team? Email us attips@the-sun.co.ukor call 0207 782 4368
Excerpt from:
Graphic pictures reveal the horror of eczema sufferer 'skinned alive ... - The Sun
Posted in Eczema
Comments Off on Graphic pictures reveal the horror of eczema sufferer ‘skinned alive … – The Sun