Daily Archives: August 13, 2017

Sensay advice bot to launch Ethereum-based cryptocurrency – VentureBeat

Posted: August 13, 2017 at 1:50 am

Sensay, a bot that connects people with other people for anonymous advice, announced today plans to launch an Ethereum-based cryptocurrency called SENSE.The bot currently has hundreds of thousands of monthly active users, founder Crystal Rose told VentureBeat earlier this year. Token sales will begin Oct. 10.

Sensay has been used by near 3 million people since its launch as an SMS bot in 2015. The bot surpassed the one million user mark in May 2016.

In an interview earlier this year, Rose told VentureBeat Sensay views monetization as a priority in order to provide its human network of advice givers incentive to use the bot and continue to offer advice on subjects ranging from relationships (most popular) to where to find dank memes.

Today, advice givers can receive tips in the form of tokens, and roughly 20 million coins have been awarded already. Once SENSE becomes available, coinholders will be immediately rewarded in a 1:1 basis, a Sensay spokesperson told VentureBeat in an email.

The currency may be made available to bots, apps, and services beyond Sensay in the future, a company spokesperson told VentureBeat.

SENSE is the second cryptocurrency launched for the bot ecosystem in recent months. This spring, chat app Kik announced plans to create its own cryptocurrency called Kin.

Sensay is currently available on Facebook Messenger, WeChat, Slack, Kik, Skype, SMS, iMessage and Telegram.

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Bitcoin Cash Hard Fork: It’ll Show Us Which Coin Is Best | Fortune.com – Fortune

Posted: at 1:49 am

On August 1, the digital currency Bitcoin split into two derivative currencies, Bitcoin Classic (BTC) and Bitcoin Cash (BCH). Far from being a rushed spinoff, as Blockstream Chief Strategy Officer Samson Mows August 7 op-ed in Fortune claims , the split was a long time coming.

The origins of the debate can be traced back to 2010, when a one megabyte per 10 minutes limit was quietly added into the Bitcoin codebase as a spam control measure. Because the value of a bitcoin was so low at the time, trading for pennies each, the limit was intended to prevent would-be attackers from overloading the network with a flood of cheap transactions.

This one simple variable gradually led to the emergence of two competing factions within the Bitcoin industry. One side wanted the limit raised to allow Bitcoin to scale with growing demand, while the other side claimed that allowing Bitcoin to grow too quickly would result in its centralization and shift to corporate control.

As the Bitcoin network grew in popularity, this one megabyte limit started being pushed up against in late 2016, but through organic network growth rather than by a flood of maliciously generated transactions. The result was that Bitcoin found itself unable to absorb increased demand: Every transaction would now be at the expense of another, and a fee bidding war drove the average transaction fee from pennies to a peak of more than $5 in June 2017.

Many worried that such high fees would hinder Bitcoins growing adoption and use, disenfranchising most of the worlds actual Bitcoin users, leaving only price speculators and those willing to pay high fees to transact in bitcoin.

After years spent at loggerheads with the other faction, the Bitcoin Cash supporters decided that rather than try to morph Bitcoin to their wishes, they would simply create a split of the ledger and let the market decide. The Bitcoin Classic chain retains the one megabyte limit and the legacy ticker symbol, BTC, while the Bitcoin Cash chain has increased the limit to eight megabytes and adopted a new ticker symbol, BCH (alternatively BCC, depending on who you ask).

Any person holding bitcoin at the time of the split on August 1 received identical amounts of each new coin at the time of the split. If you had one Bitcoin at the end of July, youd now have one BTC and one BCH in August. Rather than causing a market upset, the split achieved the desirable outcome of allowing both visions of Bitcoin to compete in the free market.

Many have decided to sell one side of the split to buy more of the other side, but more conservative holders can benefit from holding both and refraining from speculation. Preventing either of the two ideologically divided camps from pursuing their vision does no one any favors: Both camps were stuck with a version of Bitcoin they viewed as suboptimal. The split allows each coin to develop and grow in the way its supporters believe to be best.

And the markets seem to agree. The price of both tokens combined is now greater than the price of one Bitcoin before the split. In the long term, expect to see market demand coalesce around one of the two coins. Bitcoin has always belonged to the free marketmay the best coin win!

Jake Smith is a manager at Bitcoin.com .

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SpaceX to launch most powerful computer ever sent to space station – NBC Montana

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When SpaceX's Falcon 9 rocket blasts off Monday, one of the items on board will be a supercomputer built by Hewlett Packard Enterprise, dubbed the "Spaceborne Computer." When SpaceX's Falcon 9 rocket blasts off Monday, one of the items on board will be a supercomputer built by Hewlett Packard Enterprise, dubbed the "Spaceborne Computer." Related Content

NEW YORK (CNNMoney) - A SpaceX rocket is ready to deliver one of the most high-tech payloads ever to the International Space Station.

When the Falcon 9 rocket blasts off on Monday, one of the items on board will be a supercomputer built by Hewlett Packard Enterprise, dubbed the "Spaceborne Computer." If it works, it could be the most powerful commercial, off-the-shelf computer ever to operate in space.

Astronauts aboard the space station already have a bunch of devices you'd find at your local electronics store -- including HP laptops.

But a supercomputer is something different. It's a much more powerful piece of hardware that can crunch massive amounts of data and send the results to other computers in just moments.

According to Mark Fernandez, the HPE engineer who is heading up this new experiment, the space-bound supercomputer will have the ability to make one trillion calculations in a single second -- about 30 to 100 times more powerful than your average desktop computer.

Julie Robinson, the chief scientist for NASA's space station program, said if this supercomputer can function in the harsh conditions of space -- it'll be very exciting news for companies down here on earth.

Robinson points out that a huge point of interest for the private sector is taking high-quality satellite images of earth in order to track things like crop growth or oil exploration.

"What's happening is -- just as your TV now has so much more resolution -- the same thing is happening with [satellite imagery]," she said.

But the high-definition images require 200 to 300 times more data, which can clog up the communication pipeline between earth and space. That's where a supercomputer on board the space station would become hugely valuable, Robinson told CNNMoney.

"If you can process the data on board [the space station], you then only need to send down a subset of the data that's actually needed," she said.

Space-bound computers have been slow to reach such powerful data processing capabilities. A lot of the hardware on board the space station now has undergone significant retrofitting via a process called "hardening" -- which means it's been beefed up with extra protection to keep it safe in the rough conditions of space.

"By the time it goes through the hardening process, and then the tests needed to ensure it's ready to fly, the computers are many generations old," HPE's Fernandez said.

HPE's supercomputer, however, is just like one you'd buy on earth. Fernandez said the only thing different about the one flying to space is some special software that should be able to detect when the computer is exposed to something dangerous -- like high radiation levels -- and make small adjustments to keep it safe.

Will the avant-garde software be enough to ensure the supercomputer will survive in space?

Not everyone is so sure. "Some think it'll never power up or be fried within the first few minutes," Fernandez said.

We'll find out soon enough.

Fernandez said he expects to receive word the device has been plugged in and booted up sometime on September 4.

"I told them to let me know as soon as that happens -- anytime, day or night," Fernandez said with a laugh. "If it powers up, that's going to be my first relief. I will be very excited then."

Fernandez and his team will then run about 2-and-a-half hours of tests to determine if the computer is fully functional. That, he said, will be the next major victory.

Then, the plan is for scientists here on earth to keep running tests with the supercomputer for a full year to see how it fares on the space station.

If the supercomputer is still operational at the end of one year -- Fernandez said it'll pave the way for NASA to send up even more powerful computers.

And one day, a similar computer could be used by astronauts traveling to Mars.

HPE's Fernandez and NASA's Robinson both said having the ability to process large amounts of data on board a Mars mission would be a huge advantage.

That's because there could be long minutes of lag time in communicating with Mars-bound astronauts, and communications could even be cut off for days at a time.

"Such a long communication lag would make any on-the-ground exploration challenging and potentially dangerous if astronauts are not able to solve certain problems themselves," HPE explained.

"By sending a supercomputer to space, HPE is taking the first step in that direction," the company said.

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New NASA Mission Going to the International Space Station –"To Explore Mysteries of Cosmic Rain" – The Daily Galaxy (blog)

Posted: at 1:48 am

A new experiment set for an Aug. 14 launch to the International Space Station will provide an unprecedented look at a rain of particles from deep space, called cosmic rays, that constantly showers our planet. The Cosmic Ray Energetics And Mass mission destined for the International Space Station (ISS-CREAM) is designed to measure the highest-energy particles of any detector yet flown in space.

"The CREAM balloon experiment achieved a total sky exposure of 191 days, a record for any balloon-borne astronomical experiment," said Eun-Suk Seo, a professor of physics at the University of Maryland in College Park and the experiment's principal investigator. "Operating on the space station will increase our exposure by over 10 times, taking us well beyond the traditional energy limits of direct measurements."

Sporting new instruments, as well as refurbished versions of detectors originally used on balloon flights over Antarctica, the refrigerator-sized, 1.4-ton (1,300 kilogram) ISS-CREAM experiment will be delivered to the space station as part of the 12th SpaceX commercial resupply service mission. Once there, ISS-CREAM will be moved to the Exposed Facility platform extending from Kibo, the Japanese Experiment Module.

From this orbital perch, ISS-CREAM is expected to study the "cosmic rain" for three yearstime needed to provide unparalleled direct measurements of rare high-energy cosmic rays.

At energies above about 1 billion electron volts, most cosmic rays come to us from beyond our solar system. Various lines of evidence, including observations from NASA's Fermi Gamma-ray Space Telescope, support the idea that shock waves from the expanding debris of stars that exploded as supernovas accelerate cosmic rays up to energies of 1,000 trillion electron volts (PeV). That's 10 million times the energy of medical proton beams used to treat cancer. ISS-CREAM data will allow scientists to examine how sources other than supernova remnants contribute to the population of cosmic rays.

Protons are the most common cosmic ray particles, but electrons, helium nuclei and the nuclei of heavier elements make up a small percentage. All are direct samples of matter from interstellar space. But because the particles are electrically charged, they interact with galactic magnetic fields, causing them to wander in their journey to Earth. This scrambles their paths and makes it impossible to trace cosmic ray particles back to their sources.

"An additional challenge is that the flux of particles striking any detector decreases steadily with higher energies," said ISS-CREAM co-investigator Jason Link, a researcher at NASA's Goddard Space Flight Center in Greenbelt, Maryland. "So to better explore higher energies, we either need a much bigger detector or much more observing time. Operating on the space station provides us with this extra time."

Large ground-based systems study cosmic rays at energies greater than 1 PeV by making Earth's atmosphere the detector. When a cosmic ray strikes the nucleus of a gas molecule in the atmosphere, both explode in a shower of subatomic shrapnel that triggers a wider cascade of particle collisions. Some of these secondary particles reach detectors on the ground, providing information scientists can use to infer the properties of the original cosmic ray.

Technicians lower ISS-CREAM into a chamber that simulates the space environment during system-level testing at NASA's Goddard Space Flight Center in summer 2015. Credit: University of Maryland Cosmic Ray Physics Laboratory These secondaries also produce an interfering background that limited the effectiveness of CREAM's balloon operations. Removing that background is another advantage of relocating to orbit.

With decreasing numbers of particles at increasing energies, the cosmic ray spectrum vaguely resembles the profile of a human leg. At PeV energies, this decline abruptly steepens, forming a detail scientists call the "knee." ISS-CREAM is the first space mission capable of measuring the low flux of cosmic rays at energies approaching the knee.

"The origin of the knee and other features remain longstanding mysteries," Seo said. "Many scenarios have been proposed to explain them, but we don't know which is correct."

Astronomers don't think supernova remnants are capable of powering cosmic rays beyond the PeV range, so the knee may be shaped in part by the drop-off of their cosmic rays in this region.

"High-energy cosmic rays carry a great deal of information about our interstellar neighborhood and our galaxy, but we haven't been able to read these messages very clearly," said co-investigator John Mitchell at Goddard. "ISS-CREAM represents one significant step in this direction."

ISS-CREAM detects cosmic ray particles when they slam into the matter making up its instruments. First, a silicon charge detector measures the electrical charge of incoming particles, then layers of carbon provide targets that encourage impacts, producing cascades of particles that stream into electrical and optical detectors below while a calorimeter determines their energy. Two scintillator-based detector systems provide the ability to discern between singly charged electrons and protons. All told, ISS-CREAM can distinguish electrons, protons and atomic nuclei as massive as iron as they crash through the instruments.

ISS-CREAM will join two other cosmic ray experiments already working on the space station. The Alpha Magnetic Spectrometer (AMS-02), led by an international collaboration sponsored by the U.S. Department of Energy, is mapping cosmic rays up to a trillion electron volts, and the Japan-led Calorimetric Electron Telescope (CALET), also located on the Kibo Exposed Facility, is dedicated to studying cosmic ray electrons.

Overall management of ISS-CREAM and integration for its space station application was provided by NASA's Wallops Flight Facility on Virginia's Eastern Shore. ISS-CREAM was developed as part of an international collaboration led by the University of Maryland at College Park, which includes teams from NASA Goddard, Penn State University in University Park, Pennsylvania, and Northern Kentucky University in Highland Heights, as well as collaborating institutions in the Republic of Korea, Mexico and France.

The Daily Galaxy via NASA's Goddard Space Flight Center

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Local Boy Scout troop experiment about to take off for outer space … – Chicago Tribune

Posted: at 1:48 am

Wearing winter clothes, Andrew Frank entered a minus 20 degrees Celsius freezer at the Kennedy Space Center in Florida earlier this month to help insert hundreds of biological samples into a tiny device destined for a mission in space.

But the unit wouldn't quite fit into the 4-by-4-by-6-inch box required for the mission, so the 16-year-old Boy Scout with Palatine-based Troop 209 and other volunteers improvised with tinier screws and silicon tape to seal the container. After eight hours working off and on in the deep freeze, Frank was shaking from the cold, but the device was cleared for liftoff.

With that, a two-year process to build an experiment capable of testing DNA mutations in space while meeting strict NASA specifications was complete.

The project was chosen from a competition among Chicago-area troops sponsored by Boy Scouts of America and the Center for the Advancement of Science in Space, which runs the U.S. laboratory on the International Space Station. Some of the Scouts will be on hand to watch when the experiment is due to launch aboard a SpaceX rocket from the Florida space center on Monday.

"It's been a huge learning experience," said Frank, the team leader. "I had never done anything like this."

The experiment will test genetic mutations of bacteria in low gravity. Using a procedure called the Ames test, the Scouts will examine how much E. coli cultures change in space and compare that with what happens to them on Earth.

If they find changes in mutations, the Scouts said, it might suggest better ways to fight cancer or grow tissue to heal wounds.

"At the beginning, it's just really cool to do something that's going into outer space," said team mentor Norm McFarland. "By the end, the Scouts were coming up with their own solutions to problems they were finding."

Their device will take photos of each culture repeatedly throughout the flight, checking for a telltale color change from purple to yellow.

To fit a testing device into the restricted space, the Scouts tried out multiple designs, cameras and motors, finally settling on an octagon-shaped carousel that rotates the samples so they can be photographed. Sensors also track time, temperature and humidity.

The device must do all that without using more than the allotted power limit of about 2.5 watts, a small fraction of the power commonly used by lightbulbs.

When astronauts return the experiment to Earth after about a month, the Scouts will check the results, then run the same experiment under the same conditions but in normal gravity.

Some 20 Scouts, age 11 to 18, worked on the project, putting in more than 5,000 hours of meeting time.

The team had guidance from many adults including McFarland, an electrical engineer who retired from Siemens Building Technologies after helping develop numerous patents. Among those who also assisted were a microbiologist and a father who helped fabricate the aluminum parts for the device.

The Scouts themselves designed and soldered a circuit board to help make their experiment work. They even included a position sensor, so if the space station loses power temporarily, the device can reset itself.

Frank and teammate Harmon Bhasin were in Florida before the launch to explain their project at a NASA preflight news conference.

Adult volunteer Kathleen Cassady said she was impressed by how the Scouts grew during the project.

"I thought this would be a good thing to get them interested in STEM (science, technology, engineering and math)," she said, "but I never thought it would also give them the soft skills, to be able to work as a team, provide leadership and problem-solve."

Armando L. Sanchez/Chicago Tribune

Members of Palatine Boy Scout Troop 209 built this device to test genetic mutations of bacteria in low gravity. Its scheduled to launch on Monday, Aug. 14, 2017, aboard a SpaceX rocket in Florida.

Members of Palatine Boy Scout Troop 209 built this device to test genetic mutations of bacteria in low gravity. Its scheduled to launch on Monday, Aug. 14, 2017, aboard a SpaceX rocket in Florida. (Armando L. Sanchez/Chicago Tribune)

This isn't the only Scout experiment chosen for the space station. Explorer Post 2400, which includes males and females up to age 20 out of Calumet College of St. Joseph in Whiting, was chosen for the next space launch this fall, to test the effect of low gravity on peptides, which are thought to play a key role in Alzheimer's disease.

One of the faculty leaders on the project, Sandra Chimon Rogers, chairwoman of the college's department of biophysical chemistry and math, said the team developed an infrared spectrometer that fit into the tiny space allowed and cost only about $700, rather than the tens of thousands of dollars such devices often cost.

"It's an amazing opportunity for them, and more students should be aware of it," Rogers said.

In addition, a team of students from Deerfield High School won a separate competition to send their experiment on Monday's launch. They will test different materials for their ability to provide a shield from radiation, which could prove crucial to any long-range space mission, such as an expedition to Mars.

That Go For Launch! competition was sponsored by Higher Orbits, a nonprofit that promotes science and technology, and was judged in part by a former astronaut, Dorothy Metcalf-Lindenburger.

One of the students on the Deerfield team, 16-year-old Chirag Goel, said he was thrilled at the opportunity.

"To look into the night sky and to be a small part of that is humbling," Goel said. "To tell your kids I helped design an experiment to go into space ... what could be cooler than that?"

rmccoppin@chicagotribune.com

Twitter @RobertMcCoppin

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VIDEO: Research To Advance Disease Therapies Among Cargo Headed To Space Station On Dragon Monday – SpaceCoastDaily.com

Posted: at 1:48 am

By NASA // August 13, 2017

ABOVE VIDEO:The SpaceX CRS-12 mission will carry more than 20 ISS National Lab experiments to the International Space Station ranging from research on Parkinsons disease, DNA science to many others.

BREVARD COUNTY KENNEDY SPACE CENTER, FLORIDA The SpaceX Dragon cargo spacecraft is targeted for launch Monday, Aug. 14 from Kennedy Space Center for its 12th commercial resupply (CRS-12) mission to the International Space Station.

The flight will deliver investigations and instruments that study cosmic ray particles, protein crystal growth, stem cell-mediated recellularization and a nanosateliite technology demonstration.

The vehicle also will deliver supplies and equipment to crew members living aboard the station.

Here are some highlights of research that will be delivered:

Investigation studies cosmic ray particles

Cosmic ray particles reach Earth from far outside the solar system with energies well beyond what man-made accelerators can achieve. The Cosmic Ray Energetics and Mass (ISS-CREAM) instrument, attached to the Japanese Experiment Module Exposed Facility, measures the charges of cosmic ray particles ranging from hydrogen to iron nuclei.

The data collected from the CREAM instrument will be used to address fundamental science questions such as:

Do supernovae supply the bulk of cosmic ray particles?

What is the history of cosmic ray particles in the galaxy?

Can the energy spectra of cosmic rays result from a single mechanism?

Tested in several long duration balloon flights, the CREAM instrument holds the longest known exposure record for a single balloon-borne experiment at approximately 190 days of exposure. ISS-CREAMs three-year mission will help the scientific community build a stronger understanding of the fundamental structure of the universe.

Microgravity-grown protein crystals aid in understanding of Parkinsons disease

ABOVE VIDEO:The Michael J. Fox Foundation is sending an experiment to the ISS National Lab to investigate the LRRK2 protein, a key target in identifying the makeup of Parkinsons disease.

The microgravity environment of the space station allows protein crystals to grow larger and in more perfect shapes than earth-grown crystals, allowing them to be better analyzed on Earth.

Developed by the Michael J. Fox Foundation, Anatrace and Com-Pac International, the Crystallization of Leucine-rich repeat kinase 2 (LRRK2) under Microgravity Conditions (CASIS PCG 7) investigation will use the orbiting laboratorys microgravity environment to grow larger versions of this important protein, implicated in Parkinsons disease.

Defining the exact shape and morphology of LRRK2 would help scientists to better understand the pathology of Parkinsons and aid in the development of therapies against this target.

Telescope-hosting nanosatellite tests new concept

The Kestrel Eye (NanoRacks-KE IIM) investigation is a microsatellite carrying an optical imaging system payload. This investigation validates the concept of using microsatellites in low-Earth orbit to support critical operations, such as providing lower-cost Earth imagery in time-sensitive situations such as tracking severe weather and detecting natural disasters.

Sponsored by the space station U.S. National Laboratory, the overall mission goal for the investigation is to demonstrate that small satellites are viable platforms for providing critical path support to operations and hosting advanced payloads.

Growth of lung tissue in space could provide information about disease pathology

ABOVE VIDEO:The University of Texas Medical Branch will be sending human lung tissue to the ISS National Lab to better understand how lung tissue functions in microgravity in preparation for long-term spaceflight.

The Effect of Microgravity on Stem Cell Mediated Recellularization (Lung Tissue) uses the microgravity environment of space to test strategies for growing new lung tissue.

Using bioengineering techniques, the Lung Tissue investigation cultures different types of lung cells in controlled conditions aboard the space station.

The cells are grown in a specialized framework that supplies them with critical growth factors so that scientists can observe how gravity affects growth and specialization as cells become new lung tissue.

The SpaceX Dragon cargo spacecraft is targeted for launch Monday, Aug. 14 from Kennedy Space Center for its 12th commercial resupply (CRS-12) mission to the International Space Station.

Tissue mimic models such as this also have the potential to be used for assessing drug or chemical toxicity by biotechnology and pharmaceutical companies and could allow for rapid testing of new chemicals and compounds, considerably lowering the overall costs for research and development of new drugs.

The ultimate goal of this investigation is to produce bioengineered human lung tissue that can be used as a predictive model of human responses allowing for the study of lung development, lung physiology or disease pathology.

These investigations and others launching aboard CRS-12 will join many other investigations currently happening aboard the space station. Follow @ISS_Research for more information about the science happening on station.

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Primary students the first to code experiments for International Space Station – The Sydney Morning Herald

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About 24 primary students are the first in the country to code science experiments that will be launched on a rocket to the International Space Station this weekand completed by astronauts.

The students from six public schoolshave spent the past three months choosing an experiment and coding the hardware necessary to complete it in space.

AbdelelahFaisal, 11, who is in year 6 at Granville East Public School, and his group havecoded a mini-computer to take photographs in space and transmit the data back to earth, where theywill use it to create an artwork.

"We wanted to see how much light is actually in space because in space videosit's always so dark up there," Abdelelah said.

"No primary schools have ever done this beforeso this was our first opportunity to experience what uni students do."

The school's assistant principal Sarah Mellish, who has worked closely with the year 6 students involved in theproject being run by Cuberider, said it has previously only been offered to high school students.

"We were initially told primary students couldn't do the experiment and we said 'no,that's not true, we have really high expectations for them'," Mrs Mellish said.

She said the students"pickedup on it really quickly" once they started working with six year 7 students at Casula High School, and completed the project over four days.

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"Coding and robotics are becoming really common in primary schoolsand the idea of sending something into space was a really cool drawing card," Mrs Mellish said.

Emily Signorini, who is head teacher of STEM at Casula High School and led the project, said other experiments include measuring the temperature at the International Space Station and comparing it toearth to look at how a farm could be set up in space.

"One of the things the teachers have really enjoyed watching is all of the discussions that have broken off," Mrs Signorini said.

"Not just about the space station but about things like the terraforming ofMars, changing it so that it's fit for us to live on.

"As teachers, we were very surprised to hear that. They're going off on their own hypothetical journeys.

"We could have the first people to ever go to Mars in our classroom right now."

The codes and hardware to carry out the experiments will be launched from the Kennedy Space Center in Florida on Tuesday in a SpaceXrocket that is delivering supplies to the International space station.

Cuberider will also conduct the experiments in the earth's stratosphere through a balloon launch scheduled in October.

Abdelelah said the project has made him much more interested in science.

"I wasn't that interested in it until I went into this," he said.

"I'm excited to see how it's actually going to be launched and whether the experiment will work.

"And my friends are also jealous."

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Researchers encode malware in DNA, compromise DNA sequencing software – Ars Technica

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Enlarge / This data could potentially contain malware.

With everyone from academics to Microsoft looking at the prospect of storing data using DNA, it was probably inevitable that someone would start looking at the security implications. Apparently, they're worse than most people might have expected. It turns out it's possible to encode computer malware in DNAand use it to attack vulnerabilities on the computer that analyzes the sequence of that DNA.

The researchers didn't find an actual vulnerability in DNA analysis softwareinstead, they specifically made a version of some software with an exploitable vulnerability to show that the risk is more than hypothetical. Still, an audit of some open source DNA analysis software shows that the academics who have been writing it haven't been paying much attention to security best practices.

DNA sequencing involves determining the precise order of the bases that make up a DNA strand. While the process that generates the sequence is generally some combination of biology and/or chemistry, once it's read, the sequence is typically stored as an ASCII string of As, Ts, Cs, and Gs. If handled improperly, that chunk of data could exploit vulnerable software to get it to execute arbitrary code. And DNA sequences tend to see a lot of software, which find overlapping sequences, align it to known genomes, look for key differences, and more.

To see whether this threat was more than hypothetical, the researchers started with a really simple exploit: store more data than a chunk of memory was intended to hold, and redirect program execution to the excess. In this case, said excess contained an exploit that would use a feature of the bash shell to connect into a remote server that the researchers controlled. If it worked, the server would then have full shell access to the machine running the DNA analysis software.

Actually implementing that in DNA, however, turned out to be challenging. DNA with Gs and Cs forms a stronger double-helix. Too many of them, and the strand won't open up easily for sequencing. Too few, and it'll pop open when you don't want it to. Repetitive DNA can form complex structures that get in the way of all the enzymes we normally use to manipulate DNA. The computer code they wanted to use, however, had lots of long runs of the same character, which made for a repetitive sequence that was very low in Gs and Cs. The company they were ordering DNA from couldn't even synthesize it.

In the end, they had to completely redesign their malware so that its translation into nucleic acids produced a DNA strand that could be synthesized and sequenced. The latter created another hurdle. The most common method of sequencing is currently limited to reading a few hundred bases at a time. Since each base has two bits of information, that means the malware has to be incredibly compact. That limits what can be done, and it explains why all this particular payload did was open up a remote connection.

Then, there was the matter of getting the malware executed. Since this was a proof of concept, the researchers made it easy on themselves: the modified an existing tool to create an exploitable vulnerability. They also made some changes to the system's configuration to make the execution of random memory locations easier (made the stack executable and turned off memory address randomization). While that makes the test environment less realistic, the goal was simply to demonstrate that DNA-delivered malware was possible.

With everything in place, they ordered some DNA online then sent it off to a facility for sequencing. When their sequences came back, they sent them through a software pipeline that included their vulnerable utility. Almost immediately, the computer running the software connected into their host, providing them with access to the machine. The malware worked.

Given how easy the authors made thingsa known vulnerability and a number of safeguards turned offdoes this really pose a threat? There's good news and bad news here.

On the good side, there's the complications of translating computer instructions into DNA that can be synthesized and sequenced. Plus there's the issue that most sequencing machines are limited in how long a sequence they can read. The machine used in this work maxes out at 300 bases, which is the equivalent of 600 bits, and most facilities keep things shorter than that. Longer read machines are available, but they're also error prone, and any errors will typically disable the malware.

But it's also common for the software used to analyze DNA to look for places where two short sequences overlap and use that to build up longer sequences. This has the potential to expand the size of the malware considerably, although less of the analysis software pipeline will be exposed to these longer, assembled sequences.

Similar issues exist with how the malware is encoded. While the authors used each base to encode two bits, DNA analysis software handles DNA in various ways internally. For example, if sequencing doesn't provide a clear indication of what a base is, other characters may be used (for example, N for any base, or R for G or A). Any software that handles these ambiguous bases has to have a more complex encoding scheme; many simply use ASCII characters.

As a result, different pieces of software will be vulnerable to different malware encodings. While that means some software will be immune, the size of the DNA analysis pipelines typically means that a dozen or more pieces of software will be run in succession. Chances are good that at least one of them will use the same encoding as the malware.

The research community's habits are also a major point of vulnerability. The analysis software was generally not written with security in mind. Using the Clang compiler's analysis tools and HP's Fortify compiler, the authors searched a collection of open source DNA analysis software for potential vulnerabilities. They found widespread use of functions that are prone to buffer overflows (strcat, strcpy, sprintf, vsprintf, gets, and scanf)about two instances for every 1,000 lines of code. "Our research suggests that DNA sequencing and analysis have not to date received significantif anyadversarial pressure," they conclude.

The second issue is how easy it is to infiltrate malicious code onto other machines via DNA. The sequencing machines have such a high capacity, work from several different labs is run on a single machine at the same time. As a result, some of the sequences returned from the machine will end up mixed into an unrelated sample. When the researchers checked with another group that had their sequencing performed at the same time, they found that the other group's results contained 27 instances of the malware.

Separately, lots of services simply allow you to send in any DNA for sequencing, putting their software at risk. And many public repositories allow people to upload their sequence for analysis by others. So, you wouldn't even have to synthesize any DNA to have your exploit analyzedyou can simply upload the text of the sequence you've designed to someone else's data repository.

None of this means that a DNA-based exploit is around the corner. But it's a healthy warning that the research community and commercial DNA companies should look to improve their practices before this does become a problem.

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Researchers encode malware in DNA, compromise DNA sequencing software - Ars Technica

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DNA test leads brothers to reunite with mother — after 46 years – CNN

Posted: at 1:47 am

Raymond was speechless. He glanced at his younger brother, then his eyes darted back to the entrance to the Dallas Fort Worth International Airport baggage claim.

The woman continued to walk slowly toward them -- then she froze.

"Elsie?" Anthony called out, his voice a tone higher. "Raymond?" she asked.

It was an emotional reunion between a mother and her sons that had been 46 years in the making. "I love you," she whispered, kissing both men on the cheek again and again.

As they hugged their mother, Abreu and Wiggs were surrounded by their children and girlfriends, members of the media, airport employees and curious travelers -- each perhaps trying to understand what they had just witnessed.

Many months of late-night calls -- and a DNA test -- had led to that life-changing moment. Now 64-year-old Elsie Ramirez was finally face-to-face with her sons, Raymond, 47, and Anthony, 46. She hadn't seen them since they were infants. Before the meeting, she had been anxious. "I feel the butterflies ... and felt like a new butterfly," she said as she hugged her sons.

Ramirez said she left Aguadilla, Puerto Rico, in the 1970's shortly after her relationship with her husband broke down. He was in the military and stationed at Ramey Air Force Base.

Soon after the couple's relationship soured, social services in Puerto Rico became involved and the brothers and their mother were split up. Raymond Abreu -- 10 months older than his brother -- moved in with his grandparents. Soon after that, his father took him to San Antonio, Texas.

Meanwhile, baby Anthony had been adopted by the Wiggs family. Marta Wiggs and her family called the boy "Mikey," a nod to his birth name.

She fondly recalls the morning in 1971 that her late husband called and told her about a little boy who had been dropped off at the base's social services office -- and who needed a home.

"I think my dad panicked," Anthony Wiggs told CNN. "He didn't know what to do with me and he took me to someone he knew, who happened to be his sergeant in his platoon, who (also worked) for social services."

Marta Wiggs already had an 8-month-old boy and said that at the time she felt that she had everything she needed to raise another baby. She immediately agreed to take on the child. "A couple of hours later, we had Mikey in the house too," she remembered, chuckling. "We were overjoyed." By 1973, the adoption was official and the Wiggs family moved to California.

Ramirez said she looked for her boys after she moved from Puerto Rico to Massachusetts and was devastated that she couldn't find them. She said the separation caused her years of pain.

Anthony, meanwhile, had become curious about his family history. His adoptive mother showed him his birth certificate. He searched the white pages each day and would make a few calls to Puerto Rico, New York and Florida. Eventually he connected with Raymond's ex-wife living in Texas who put the brothers in touch. Both believed their mother was dead. Everybody they knew to ask told them so. But still they weren't convinced.

"My brother found me first when I was 28 and he continued the mission to find mom," Raymond Abreu said. "He was just die hard, 'I'm going to find her.'"

In May this year they made a massive breakthrough. Anthony's girlfriend bought him a DNA test for his birthday. He was able to connect with a large database of historical records to find living relatives who shared the same DNA.

The test threw up a match for Wiggs' cousin, Elsie Ramirez' nephew, who he then tracked down. The man broke some stunning news -- Elsie was alive and living in Massachusetts. "I got on Facebook and just started typing her name," Anthony Wiggs said. "I ended up on a Facebook page with her best friend."

Wiggs got Elsie's cell phone number from her friend and left a voice message. His mother heard his voice on her phone just an hour later. "She was actually at the mall in the restroom," Wiggs said. "There was a lady in there next to her who heard her screaming and crying out of joy."

Still in shock, Elsie explained why she was so thrilled to the stranger and then stepped outside to call her son. Anthony had Raymond join the call. Abreu said his mother told them in Spanish "I always prayed, I always tried to look for you." Then all three cried together.

Four of her five Texas grandchildren were at the airport to greet Ramirez when she made her long-awaited arrival recently. They described the experience of being introduced to a new grandma as "surreal, exciting -- and nerve-racking."

Raymond and Anthony also have seven other half-brothers and sisters -- Elsie's other children. "My brother was like, you know what, let's just take it one step at a time," Abreu said. "Let's get mom here to Dallas. Let's concentrate on her. And next we will concentrate on our siblings. I think we made the right choice. It was too much to handle."

After being separated by almost 2,000 miles, they are excited about starting a relationship together, as a family. They spent their weekend hanging out at the pool, cooking, going out to dinner, and relaxing. Nobody could sleep, so they stayed up late chatting.

Elsie said she is eager to make up for missed moments and stay as close to her boys as possible. "It doesn't matter if we're older now, we're still her babies," Wiggs said as he smiled, receiving another kiss on the cheek from his mom.

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DNA test leads brothers to reunite with mother -- after 46 years - CNN

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Now, DNA sensor for quick pathogen detection – The Hindu

Posted: at 1:46 am

An ultrasensitive DNA sensor that can detect S. pyogenes, a bacterium which causes a wide range of diseases in about 30 minutes has been developed. The DNA chip is highly specific device for S. pyogenes. The conventional method of identification takes 18-24 hours and the basic culture test does not specifically help distinguish S. pyogenes.

From mild skin and throat infections to life-threatening toxic shock syndrome, S. pyogenes infections affect 700 million people every year. If not treated during early stages of the infection, S. pyogenes can even lead to rheumatic heart disease (heart valves damage).

The sensor was developed by scientists from CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB) and National Centre for Disease Control (NCDC) Delhi, and the results were published in the International Journal of Biological Macromolecules.

The DNA chip based sensor consists of a carbon electrode embedded with gold nanoparticles. By means of a bioinformatics study, the researchers were able to design probes which are specific for S. pyogenes.

The working electrode surface of the device is attached with several small-sized, single-stranded DNA probe specific to the pathogen. When patients DNA, isolated from throat swabs, are placed on the surface, they bind to the complementary single-stranded DNA on the device and an electrochemical change is seen. This is measured using a differential pulse voltammetry.

Identification of pathogen

For confirmation, traditional culture test was used and the results matched with the DNA sensor. The sensor is highly sensitive and could detect even 60-65 bacteria in a 6 microlitre sample. It could identify the pathogen even at very low concentrations of DNA. We were able to get a peak with a concentration of even 0.001nanogram per 6 microlitre, explains Swati Singh from IGIB and the first author of the paper.

The sensor was found to be stable for 12 months with only 10% loss in initial current peak on storage at 4 degree C. We are working on construction of different biosensors for different pathogens. Early and quick diagnosis can help in preventing the diseases and seek medical treatment at the early stage of infection, adds Dr. Ashok Kumar, Chief Scientist/Professor (AcSIR) at IGIB and corresponding author of the paper.

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Now, DNA sensor for quick pathogen detection - The Hindu

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