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Monthly Archives: July 2017
Will Bitcoin Tear Itself Apart? – Bloomberg
Posted: July 10, 2017 at 7:49 pm
Its time for bitcoin traders to batten down the hatches.
The notoriously volatile cryptocurrency, whose 160 percent surge this year has captivated everyone from Wall Street bankers to Chinese grandmothers, could be headed for one of its most turbulent stretches yet.
Blame the bitcoin civil war. After two years of largely behind-the-scenes bickering,rival factions of computer whizzeswho play key roles in bitcoins upkeep are poised to adopt two competing software updates at the end of the month. That has raised the possibility that bitcoin will split in two, an unprecedented event that would send shockwaves through the $41 billion market.
While both sides have big incentives to reach a consensus, bitcoins lack of a central authority has made compromise difficult. Even professional traders whove followed the disputes twists and turns arent sure how it will all pan out. Their advice: brace for volatility and be ready to act fast once a clear outcome emerges.
Its a high-stakes game of chicken, said Arthur Hayes,a former market maker at Citigroup Inc. who now runs BitMEX, a bitcoin derivatives venue in Hong Kong. If youre a trader, theres a lot of uncertainty as to what happens. Once theres a definitive signal about what will be done, the price could move very quickly.
(Detailed summary of key dates and potential outcomes at bottom.)
Behind the conflict is anideological split about bitcoins rightful identity. The community has bitterly argued whether the cryptocurrency should evolve to appeal to mainstream corporations and become more attractive to traditional capital, or fortify its position as a libertarian beacon; whether it should act more as an asset like gold, or as a payment system.
The seeds of the debate were planted years ago: To protect from cyber attacks, bitcoin by design caps the amount of information on its network, called the blockchain. That puts a ceiling on how many transactions it can process -- the so-called block size limit -- just as the currencys growing popularity is boosting activity. As a result, transaction times and processing fees have soared to record levels this year, curtailing bitcoins ability to process payments with the same efficiency as services like Visa Inc.
To address this problem, two main schools of thought emerged. On one side are miners, who deploy costly computers to verify transactions and act as the backboneof the blockchain. Theyre proposing a straightforward increase to the block size limit.
On the other is Core, a group of developers instrumental in upholding bitcoins bug-proof software. They insist that to ease blockchains traffic jam, some of its data must be managed outside the main network. They claim that not only would it reduce congestion, but also allow other projects including smart contracts to be built on top of bitcoin.
But moving data off the blockchain effectively diminishes the influence of miners, the majority of whom are based in China and who have invested millions on giant server farms. Not surprisingly, Cores proposal, called SegWit, has garnered resistance from miners, the most vocal being Wu Jihan, co-founder of the worlds largest mining organization Antpool.
SegWit is itself a great technology, but the reason it hasnt taken off is because its interest doesnt align with miners, Wu said.
Still, after previous counter-proposalschampioned by Wu fell through, miners last month agreed to compromise and support SegWit, in exchange for increasing the block size. Wu says the plan will alleviate short-to-medium term congestion and give Core enough time to flesh out a long-term solution. That proposal is what is known as SegWit2x, which implements SegWit and doubles the block size limit.
You can think of the SegWit2x proposal as an olive branch, said Wu.
Support for SegWit2x has reached levels unseen for previous solutions. About 85 percent of miners have signaled they are willing to run the software once its released on July 21, and some of bitcoins largest companies have also jumped on board.
The unprecedented level of endorsement is partly prompted by anxiety of bitcoin losing its dominant status to ethereum, a newer cryptocurrency whose popularity has soared thanks to its ability to run smart contracts and its more corporate-friendly approach.
Still, hardliners say that after more than two years of bitter arguments, a split would let people part ways to explore different visions, even if prices crash.
Some of Core supporters are pushing a separate agenda called UASF (user activated soft fork). Starting from Aug. 1, it will reject transactions not compliant with SegWit. If a majority of miners do not adopt SegWit by then, two versions of bitcoin would come into existence, triggering a currency split.
Its moderates versus extremists, saidAtlanta-based Stephen Pair, chief executive officer of BitPay, one of the worlds largest bitcoin wallets. It depends on how much a person values the majority of people staying on one chain at least for a little while longer, versus splitting and allowing each pursuing their own vision for scaling.
Many Core developers continue to reject SegWit2x because they see its development and implementation as being too rushed, which they say could undermine the software underpinning bitcoin.
To suggest a hard fork happen significantly faster than even the most minor of changes in recent history is irresponsible and dangerous, said Matt Corallo, a Core contributor and former co-founder of Blockstream, which stands to benefit from SegWit.
Below is an outline of the main events that could unify or divide bitcoin:
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An Italian bank’s server was hijacked to mine bitcoin – Quartz
Posted: at 7:49 pm
Ah, those were the days, when you could steal a bit of a companys server power and mine some valuable bitcoin all for yourself.
During a presentation at a conference last week, British cybersecurity experts had some tales to tell of surreptitious and sometimes illegal bitcoin mining in the time before huge computing power was required to turn a profit at the activity. In January 2015 the British cybersecurity firm Darktrace was called to investigate a possible intrusion in the systems of an Italian bank. Darktrace uses artificial intelligence techniques to detect aberrations in computer systems.
The firm discovered streams of data were being transmitted from one of the banks servers to a European crime syndicate, Dave Palmer, director of technology at Darktrace, told the Research and Applied AI Summit in London July 30. It was a fairly well known European criminal botnet, said Palmer, director of technology at Darktrace. The data was not customer data; it turned out to be a fairly buggy implementation of bitcoin mining software.
The hijacked Italian bank server was discovered rapidly, Palmer told Quartz, and it was disabled within less than an hour of it beginning to mine bitcoin. I dont think they made very much money out of it, he says.
2014 was the heyday of criminal bitcoin mining activity. It was super fashionable to have coin mining going on alongside sending spam from botnets, he says. The case of the banking server was rare because it was usually laptops or desktop computers that were hit by this type of malware, Palmer said.
Darktrace didnt have data for the number of bitcoin mining malware cases from that period, but Palmer says it felt like it was a daily occurrence. By contrast, the firm has only detected 24 such cases in the last six months, across the 24,000 sites it monitors. It has really dropped off, he says.
While sophisticated cyber criminals did steal computing power for bitcoin mining in those days, it was far less common than employees casually mining from their standard-issue corporate laptops. Weve seen normal employees running these services on their workstations overnight, Palmer says. No surprise; people do all sorts of things like peer-to-peer file sharing and hosting Tor nodes [infrastructure for the anonymized network thats part of the dark web], so I bet there are a load of coin mining stories all over the place.
But some employees took their cryptocurrency enthusiasm a step too far. Darktrace has found servers concealed by staff in corporate data centers mining bitcoin non-stop. The servers benefit from the special cooling systems and reliable power supply at the data centers. We found employees had procured some servers, [and] had hidden them under the data center false flooring, Palmer says. They were off-the-record servers that no one recognized, mining coins 24/7.
The days of such secret bitcoin mining are now over. Too much computing power is required to profitably mine bitcoins; the scene is now dominated by professional outfits with thousands of servers stored in giant, purpose-built warehouses. Processing power devoted to bitcoin mining has risen by 770-fold since 2014, leaving little chance of profit for servers hidden in data centers or laptops churning away after work. I think we have seen the last of successful coin mining, Palmer says.
Correction: An earlier version of this post mistakenly said Darktrace investigated the Italian banks server in 2014.
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Why Bitcoin Is Booming – Wall Street Journal (subscription)
Posted: at 7:49 pm
Wall Street Journal (subscription) | Why Bitcoin Is Booming Wall Street Journal (subscription) Who says only the government can make money? This year the value of the private currency bitcoin has climbed to unprecedented levels, while at the same time becoming far less volatile than in previous periods of rapidly increasing demand. Bitcoin has ... |
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Life on the Moon: China Is Testing a Self-Sustaining Space Station That Could Allow Long-Term Lunar Living – Newsweek
Posted: at 7:49 pm
While some nations may be content to simply set foot on the moon, China has bigger things in mind. President Xi Jinping has said he wants his country to become a force in space exploration, and the plan is to start at the celestial body closest to Earth.
China wants to send a probe to the dark side of the moon by next year, and put astronauts on its surface by 2036, Reuters reports. But those astronauts may be staying for a bit longer than Neil Armstrong and Buzz Aldrin: As part of its Lunar Palace 365 project, China is testing a self-sustaining space station that provides inhabitants with everything a person needs to survive, which could lead to extended stays on the moon.
Related: How rocket fuel mined from the moon will get us to Mars
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On Sunday, four students atBeihang Universityin Beijing entered Lunar Palace-1, a 160-square-meterbioregenerative life-support base located in one of the city's suburbs. They replaced a group who lived inside the station for 60 days, but the latest batch of students to call Lunar Palace-1 home will not leave until they've been living self-sufficiently for 200 days."I'll get so much out of this," Liu Guanghui, a Ph.D. studentwho entered the bunker on Sunday,told Reuters. "It's truly a different life experience."
The station's specifications have been meticulously curated. "We've designed it so the oxygen [produced by plants at the station] is exactly enough to satisfy the humans, the animalsand the organisms that break down the waste materials," said Liu Hong, the project's principal architect.
While living in Lunar Palace-1, students will recycle everything from leftover plant matter to their own waste. The latter task may bring to mind the Matt Damoncharacter Mark Watney in the 2015 film The Martian, in which an astronaut was forced to jerry-rig a space station to support him after he was left on Mars. In addition to using his own waste to fertilize plants, Watney had to cope with the psychological toll of being isolated from the outside world. The same is true of the Chinese students testing Lunar Palace-1.
"They can become a bit depressed," Liu Hong said of the students. "If you spend a long time in this type of environment it can create some psychological problems."
Students are given specific daily tasks that help keep their spirits up, but it's difficult to gauge the psychological effect of living in an environment so radically different than what a person is used to. When NASA astronaut Scott Kelly returned from living on the International Space Station for 340 consecutive days, he spoke of how the psychological stress was "harder to quantify and perhaps as damaging" as any physical changes he experienced.
Liu Hui, a student who participated in the initial 60-day experiment at Lunar Palace-1, said she at times"felt a bit low" at the end of the day. The students currently in the station will be there for more than three times as long as Liu Hui, so the psychological effect of a prolonged stay remains to be seen. It's a trick problem, but one that China and the rest of the world will have to negotiate if humanity ever wants to colonize anything outside of the Earth's atmosphere.
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Life on the Moon: China Is Testing a Self-Sustaining Space Station That Could Allow Long-Term Lunar Living - Newsweek
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China Launches 200-Day Test Of Self-Sustaining Space Station – HuffPost
Posted: at 7:49 pm
BEIJING (Reuters) - Sealed behind the steel doors of two bunkers in a Beijing suburb, university students are trying to find out how it feels to live in a space station on another planet, recycling everything from plant cuttings to urine.
They are part of a project aimed at creating a self-sustaining ecosystem that provides everything humans need to survive.
Four students from Beijing University of Aeronautics and Astronautics entered the Lunar Palace-1 on Sunday with the aim of living self-sufficiently for 200 days.
They say they are happy to act as human guinea-pigs if it means getting closer to their dream of becoming astronauts.
Ill get so much out of this, Liu Guanghui, a PhD student, who entered the bunker on Sunday, said. Its truly a different life experience.
President Xi Jinping wants China to become a global power in space exploration, with plans to send the first probe to the dark side of the moon by 2018 and to put astronauts on the moon by 2036. The Lunar Palace 365 experiment may allow them to stay there for extended periods.
STR via Getty Images
For Liu Hong, a professor at Beijing University of Aeronautics and Astronautics and the projects principal architect, said everything needed for human survival had been carefully calculated.
Weve designed it so the oxygen (produced by plants at the station) is exactly enough to satisfy the humans, the animals, and the organisms that break down the waste materials, she said.
But satisfying physical needs is only one part of the experiment, Liu said. Charting the mental impact of confinement in a small space for such a long time is equally crucial.
They can become a bit depressed, Liu said. If you spend a long time in this type of environment it can create some psychological problems.
Liu Hui, a student leader who participated an initial 60-day experiment at Lunar Palace-1 that finished on Sunday, said that she sometimes felt a bit low after a days work.
The projects support team has found mapping out a specific set of daily tasks for the students is one way that helps them to remain happy.
But the 200-day group will also be tested to see how they react to living a for period of time without sunlight. The projects team declined to elaborate.
We did this experiment with animals... so we want to see how much impact it will have on people, Liu, the professor, said.
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China Launches 200-Day Test Of Self-Sustaining Space Station - HuffPost
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The Space Station Fires Music-Playing Satellites Into Orbit – Inverse
Posted: at 7:49 pm
A group of five softball-sized satellites have had quite the journey: After a SpaceX Falcon 9 rocket blasted them into space, astronauts on the International Space Station received the tiny instruments, and on July 7 they shot them into Earths orbit like cannonballs, whose epic flight is shown in the image below.
These five mini-satellites are cubes, not spheres, and they comprise a fleet of instruments called BIRDS, developed by AMSAT-UK, a private organization that designs, builds, and operates amateur satellites. Their mission, aided by the International Space Station, is to improve radio communications from satellites to the receiving stations used by regular folks down on Earth, aka amateurs.
Each of the five BIRD satellites is identical and built by an international team comprised of five disparate nations Bangladesh, Nigeria, Mongolia, Ghana, and Japan. As the little cubes zip around Earth, the radio operators will try and pass control of the satellites between different ground stations around the globe, with an added game-like component: If the ground stations can successfully send data to the satellites, Earthlings everywhere will be rewarded with space-made music.
To get the music, global researchers will upload digital music data (MIDI files) to the little cubes as they pass overhead, and the satellites themselves will transform the data into music using a vocal simulator. This processed music will then be emanated down to anyone interested in listening to these cosmic sounds. AMSAT-UK provides directions for tuning in here, and says that all one needs is a common hand-held receiver and hand-made Yagi antenna positioned to track the satellite at each given pass over the region.
The International Space Station shoots CubeSats into orbit using a Star Wars-like weapon, the double-barreled JEM Small Satellite Orbital Deployer, which has no malicious or defensive capabilities; it simply fires little cubes into space, sending them to their appropriate locations in Earths orbit.
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The Space Station Fires Music-Playing Satellites Into Orbit - Inverse
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One small step for US-China space cooperation – SpaceNews
Posted: at 7:49 pm
A Chinese DNA experiment was among the 25 NanoRacks-brokered experiments a SpaceX Dragon delivered to ISS in early June. Credit: NASA
This articleoriginally appeared in the June 19, 2017 issue of SpaceNews magazine.
Collaboration between China and the United States in space is difficult. Federal law prohibits NASA from bilateral cooperation with China unless the agency first receives congressional approval. Export control restrictions prevent U.S. companies from selling hardware to Chinese companies, or launching satellites on Chinese rockets.
One initiative, though, could open the door for greater cooperation between the two space powers, eventually. One of the payloads delivered to the International Space Station on a Dragon cargo spacecraft in early June was an experiment developed by Deng Yulin, a professor at the Beijing Institute of Technology in China. The experiment will test the effects of the space radiation environment on DNA.
The experiment was one of more than 25 brought to the station by NanoRacks, the Houston-based company whose services include delivering and operating experiments on the ISS. What made the experiment stand out was not so much its science or technology but that it was the first Chinese-built experiment to go to the station.
Jeffrey Manber, chief executive of NanoRacks, said the decision to fly the payload was based on business, not politics. Why are we working with China? Because theyre in space, he said during an event in New York June 5, the same day the Dragon berthed to the station.
The experiment flew once before on a Chinese mission, Manber said, with an abnormality detected in the DNA. We dont know yet if its due to the microgravity or the radiation, he said, hence the desire by Deng to fly it again, this time on the ISS.
The experiment was able to navigate a narrow path to overcome legal obstacles to U.S.-China space cooperation. Because the agreement is with NanoRacks, and not NASA, it does not violate existing limitations on bilateral cooperation between NASA and China. Moreover, since the experiment is imported to the United States, it does not run afoul of export control restrictions.
The company, in a June 5 statement, emphasized that the experiment will remain installed on a NanoRacks platform inside the station, with no access to NASA or other ISS systems. There is, NanoRacks added, no transfer of technology between NASA and China. NanoRacks also worked with NASA to ensure there were no issues flying the experiment.
For us, its not about a political statement, but that we now have another unique international customer, Manber said in that statement.
While the flight of that experiment may not have had geopolitical motivations, it might yet have geopolitical implications. In the U.S., the experiment got very little attention until after its launch. However, in China, it was major news, where it was seen as a milestone. This is a new model of cooperation that we can follow in the future, Deng told the state-run Xinhua news agency.
If a Chinese experiment can fly on the ISS, how else could the United States and China cooperate in space? For now, there are no signs of major changes in current U.S. policy, but its clear the issue cannot be ignored, especially as Chinas spaceflight capabilities grow.
Theyre very active, NASA Acting Administrator Robert Lightfoot said at a June 8 hearing of the House Science Committee, when asked about Chinese space capabilities. For us, we have to decide at some point whats going to be our interaction with them.
Manber has his own ideas of how he would like to work with the Chinese in the future. They have a space station as well, he said, and Im going to work as hard as I can to make it international.
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200,000-Year-Old Tooth Reveals Clues About Mysterious Human … – Live Science
Posted: at 7:47 pm
Scientists say the molar tooth found in Denisova Cave in Siberia estimate the tooth is at least 20,000 years older than previously examined Denisovan fossils.
DNA in a fossil from a young girl has revealed that a mysterious extinct human lineage occupied the middle of Asia longer than previously thought, allowing more potential interbreeding with Neanderthals, a new study finds.
Although modern humans are the only surviving human lineage, other hominins which include modern humans, extinct human species and their immediate ancestors once lived on Earth. These included Neanderthals, the closest extinct relatives of modern humans, as well as the Denisovans, who lived across a region that might have stretched from Siberia to Southeast Asia.
In 2010, researchers analyzed DNA from fossils to reveal the existence of the Denisovans, suggesting the lineage shared a common ancestor with Neanderthals. However, the Denisovans were nearly as genetically distinct from Neanderthals as Neanderthals were from modern humans, with the ancestors of Denisovans and Neanderthals splitting about 190,000 to 470,000 years ago. [Denisovan Gallery: Tracing the Genetics of Human Ancestors]
The 2010 study also revealed that the Denisovans might have interbred with modern humans thousands of years ago just as Neanderthalsdid. Subsequent research suggested that genetic mutations from Denisovanshave influenced modern human immune systems, as well as fat and blood sugar levels.
However, much remains unknown about the Denisovans, since all fossil evidence of them until now was limited to just three specimens: one finger bone and two molars. All three fossils were unearthed from Denisova Cave, after which the Denisovans are named, in the Altai Mountains in Siberia.
Now, scientists have revealed that they have a fourth Denisovan fossil a "baby tooth" that likely fell from the jaw of a 10- to 12-year-old girl, said study lead author Viviane Slon, a paleogeneticist at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.
"Any additional Denisovan individual that we can identify at this point is very exciting for us," Slon told Live Science.
The crown of the "baby" molar was almost completely worn away when researchers unearthed it. To help preserve the fossil, the researchers used 3D X-rays of the tooth to help find the best way to extract as little powder from the molar as possible. Next, they analyzed what little surviving DNA they could from about 10 milligrams of tooth powder, confirming that the fossil belonged to a Denisovan girl.
The deep layer of sediment in which this molar was found ranges from 128,000 to 227,000 years old. This age makes the tooth one of the oldest human specimens discovered in central Asia to date, and about 50,000 to 100,000 years older than the first known Denisovan fossil.
"This would indicate that Denisovans were present in the Altai area for a very long time at least as long as modern humans have been in Europe, if not much more," Slon said. Such a long span of time increases the chances that the Denisovans and the Neanderthals may have interacted and interbred, the researchers added.
These new findings, combined with previous data, suggest that there may have been low levels of genetic diversity among the Denisovans, comparable to the lower range of modern human genetic diversity seen among small or secluded populations.
"The low genetic diversity we infer for the Denisovans can most probably be linked to their small population size," Slon said. "This is similar to what has been inferred for Neanderthals. Both groups of archaic hominins seem to have had a far smaller population size than humans today."
Still, the researchers noted that because all four Denisovan fossils unearthed to date come from the same place, it is possible that they represent an isolated population and that Denisovan genetic diversity across
their entire geographic range was greater than that seen in these isolated samples. Additional fossils from Denisovans from other locations would help scientists more comprehensively gauge Denisovans' genetic diversity across space and time, Slon said.
The scientists detailed their findingsonline July 7 in the journal Science Advances.
Original article on Live Science.
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How we’ve evolved to fight the bugs that infect us – The Conversation AU
Posted: at 7:47 pm
Its the ability of our immune system to remember past infections, and pass this memory on to our kids, that allows us to survive infectious diseases.
This is the second article in a four-part series looking at how infectious diseases have influenced our culture and evolution, and how we, in turn, have influenced them.
Its easy to feel our survival is under threat from new and emerging infectious diseases that are going to wipe out the human race, or at least end our current way of life. The recent outbreaks of Ebola in West Africa re-ignited our interest in pandemics and reminded us of our potential frailty in the face of an overwhelming enemy.
With so many microbes capable of hijacking and destroying us, how are we as a species still enduring?
Humans are unique in the world. We are avid collectors of infectious diseases acquired from our environment throughout our evolution.
We share with our invaders a need to survive and propagate our genes. Infectious pathogens, such as bacteria and viruses, are parasitic they have to find and infect a susceptible host in order to maintain themselves and propagate. Therefore, its not really in their best interests to kill us. Our relationship with pathogens is shaped by our capacity to evolve genetically, to modify our behaviour, or to force the pathogens to evolve so that we all survive.
Viruses such as influenza replicate and spread to new hosts before the original host gets sick (with influenza symptoms such as a sore throat and sneezing), meaning the parasite can survive and thrive in new hosts.
On rare occasions the death of the host is necessary for the pathogen to reproduce. One example is trichinellosis (also known as trichinosis), which is caused by eating undercooked or raw meat from animals (usually carnivores and omnivores) infected with a worm (nematode).
To survive in the host the worm constructs a capsule around itself to avoid the immune system. The immature worms in the meat cause muscle weakness and paralysis, and eventually death, in the host. This means the victim is defenceless to predators that may come and gobble it up, thus giving the worm a new host to infect.
This is an old disease that we tackle either by avoiding eating meat (possibly the reason some religions avoid eating pork), or through cultural adaptation such as overcooking.
Evolutionary pressures through Darwinian selection, survival of the fittest, constantly shape life on Earth. This innate ability to adapt has enabled humans to develop defence mechanisms to counter some of the most devastating pathogens.
Malaria is a parasite of red blood cells that is estimated to have caused 429,000 deaths in 2015. When malaria became a human disease (it is thought to originate in primates) is unclear. One thing that is clear is that it emerged long enough ago for humans to evolve innate defences.
Sickle cell mutation is a potentially fatal blood disorder seen mainly in Africa. This mutation in a haemoglobin gene (responsible for red pigment in blood cells) is one of a number of genetic traits that actually protect against malaria. People who have this genetic mutation are protected against malaria and thus likely to reproduce and pass on their evolutionary advantage.
A second genetic mutation that protects humans against malaria affects an essential enzyme for red blood cell function. But individuals with this mutation may also develop life-threatening anaemia (deficiency in the number or quality of red blood cells) due to the destruction of red blood cells as a side effect of treatment with some modern anti-malarial drugs.
Perhaps the most significant and wondrous part of the evolutionary machinery that enables the human race to keep one step ahead of the pathogens is the major histocompatibility complex (MHC). The MHC proteins on the surface of our white blood cells evolved along with the vertebrates (animals with a spine), which makes them our oldest defence mechanism.
We have different types of white cells: mobile ones in the blood (lypmphocytes) and resident ones in lymph nodes (macrophages). When there is an infection the macrophages gobble up the bugs and present proteins from the organism on their surface like signals.
The lymphocytes containing MHC molecules that recognise this protein bind on. (Our immune system has memory cells that are produced after vaccination or past infections so we can remember how to fight them next time.) The lymphocytes then produce chemicals that recruit more lymphocytes to help. These multiply and you end up with a swollen gland.
Our bodys ability to remember past infections is one of the reasons the entire population of London didnt perish during the Black Death. MHC molecules are passed on to our offspring, which explains why we have such a wide variety of these molecules. When a disease enters a population for the first time it always more lethal than subsequent introductions because some people are now immune, and people have been born to the survivors.
Not all co-evolution leads to changes in human genetics, especially if there is no impact on our ability to procreate. Human tuberculosis is a chronic disease that continues to plague the world with little evidence that humans have developed any ability to resist infection. This is interesting because it is likely to have co-evolved with us from Neolithic times.
We will continue to face new and emerging diseases. So far our capacity to adapt and respond has served us well. But some scientists believe humans are no longer evolving due to the removal of many selection pressures, most importantly things that cause premature death.
The question is whether we are up to the challenges posed by what comes next. Perhaps the most pressing issue facing us now is that bugs seem to be evolving faster than we can create things to kill them known as anti-microbial resistance.
The spectre of life without antibiotics is terrifying given we never did overcome bacterial infections through evolution. Instead we used our ingenuity. Our future will reflect how well we exercise our collective intellect and will to dodge this bullet.
Read the first instalment in the series:
Four of the greatest infectious diseases of our time and how were overcoming them
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How we've evolved to fight the bugs that infect us - The Conversation AU
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Scientists revive an extinct virus using off-the-shelf DNA – Engadget
Posted: at 7:47 pm
As odd as it sounds, reviving the virus would most likely be helpful. The pharmaceutical company Tonix funded the work in hopes of using the relatively benign horsepox as a transport method for a more effective smallpox vaccine. It would also let scientists use other viruses for fighting diseases, such as introducing cancer-fighting systems using the vaccinia virus. If you could generate the necessary viruses on demand, it'd be that much easier to prevent or defeat illnesses that might otherwise have free rein.
The threat, as you might guess, comes from the ease of synthesizing a virus. The horsepox strain in question isn't a threat to humans or even horses, but it might only take the right genetic know-how, several months' work and a relatively modest shopping budget (this group spent $100,000) to do the same for a dangerous virus. A hostile nation or extremist group could theoretically engineer a virus and spark an outbreak in a rival country. It's not extremely likely -- they'd need access to both the DNA and corrupt scientists, and would have to take the risk that they might accidentally infect their own people.
It's not impossible, though, and it's that risk which might prevent further work. Nature and Science have refused to publish the relevant research paper because they're worried about the "dual-use" potential for the findings. They don't want to help create a bioweapon, after all. The researchers say their paper deliberately avoids providing so much information that newcomers could create their own viruses, though, and there are concerns that denying the paper might be stifling crucial progress. For better or for worse, this discovery may end up sitting in limbo for a long time.
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Scientists revive an extinct virus using off-the-shelf DNA - Engadget
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