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Monthly Archives: June 2017
Patient-inspired research uncovers new link to rare disorder – Baylor College of Medicine News (press release)
Posted: June 23, 2017 at 5:47 am
Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery. The condition, also known as peroxisomal biogenesis disorder, had been linked only to lipid or fat metabolism. Now, as a team of scientists from several institutions, including Baylor College of Medicine, reveals in PLoS Genetics, the condition also affects sugar metabolism. The discovery of this connection in animal models can potentially lead to treatments that might improve the condition.
Meeting this patient at Texas Childrens Hospital inspired me to begin a research investigation to learn more about this disorder, said first and corresponding author Dr. Michael Wangler, assistant professor of molecular and human genetics at Baylor College of Medicine. The family of the patient found out about this research and offered to help. They started Zellfest, a fundraising event in San Antonio, Texas, that has partially supported our investigation. This led us to study this disorder in the fruit fly model in collaboration with the research team led by Dr. Hugo Bellen, professor of molecular and human genetics and investigator at the Howard Hughes Medical Institute at Baylor College of Medicine.
Peroxisomal biogenesis disorder results from defects in the genes that form the peroxisomes, essential micro-machines inside the cell that are involved in breaking down and producing certain lipids. When peroxisomes do not form, people develop a wide range of conditions that may include poor muscle tone, seizures, hearing and vision loss, poor feeding, skeletal abnormalities, as well as life-threatening problems in organs such as the liver, heart and kidney. There is no cure or treatment, other than palliative care.
Its been well established that several lipid pathways are altered in this disease; these are known peroxisomal functions, but there has been very little focus on other parts of metabolism. Everybody was thinking this was mainly a lipid disorder, Wangler said.
The researchers genetically engineered the laboratory fly, Drosophila, to lack two of the genes that are needed to make peroxisomes, PEX2 and PEX16, and then analyzed the flies metabolism.
We began a collaboration with Dr. James McNew, professor in biosciences at Rice University, who had started looking at flies using a metabolomics approach, Wangler said. Metabolomics is like taking a snapshot of all the metabolism of an organism by measuring hundreds of small molecules all at once, rather than focusing on one molecule at a time. We analyzed lipids, small carbohydrates, amino acids, cholesterol and small lipids. This approach gave us a general view of the metabolism of the organism.
The scientists found that the flies lacking the peroxisome genes had many of the problems observed in patients. The scientists learned, for instance, that these flies had short lives and locomotor problems. Their thorough analysis suggests that flies without PEX genes represent an animal model in which to further investigate the human condition.
In addition, we were surprised to discover that these flies were very sensitive to low-sugar diet, Wangler said. They cannot tolerate a low-sugar diet as well as normal flies; without sugar, flies without peroxisomes appear to be starving.
The researchers also applied a metabolomics approach to mice genetically engineered to lack a mouse PEX gene. As they had found in the flies, mice without peroxisomes also had alterations in the metabolism of sugars.
Our understanding is that the enzymes that break down sugars are not directly connected to peroxisomes, Wangler said. We are continuing our investigations and hope they will lead us to better understand how sugar metabolism is linked to peroxisomal biogenesis disorders.
Peroxisomes also play a role in common diseases such as Alzheimers and cancer, Wangler said. Studying this rare disease can help us understand peroxisomes better, and, in turn, that knowledge will help clarify the role of peroxisomes in Alzheimers and other disorders. Rare diseases can help understand issues that also contribute to more common diseases.
Other authors that contributed to this work include Yu-Hsin Chao, Vafa Bayat, Nikolaos Giagtzoglou, Abhijit Babaji Shinde, Nagireddy Putluri, Cristian Coarfa, Taraka Donti, Brett H. Graham, Joseph E. Faust, Ann Moser, Marco Sardiello and Myriam Baes. The authors are affiliated with one of more of the following institutions: Baylor College of Medicine, Texas Childrens Hospital, KU Leuven, Rice University and the Howard Hughes Medical Institute.
This work was supported by the Clayton Murphy Peroxisomal Disorders Research Fund at Baylor College of Medicine, National Institutes of Health K08 (NS076547) award to Michael Wangler, a grant by the Simmons Family Foundation to foster collaborative efforts between Rice University and Texas Childrens Hospital, awarded to Michael Wangler, Hugo Bellen and James McNew, as well as the support of Hugo Bellen, a Howard Hughes Medical Investigator.
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Patient-inspired research uncovers new link to rare disorder - Baylor College of Medicine News (press release)
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Lifestyle Changes Might Prevent or Slow Dementia – Twin Falls Times-News
Posted: at 5:47 am
THURSDAY, June 22, 2017 (HealthDay News) -- Simple changes to your lifestyle might delay the start of dementia or slow its progression, a new report suggests.
Some scientific evidence indicates that keeping your mind active through "cognitive training," controlling your blood pressure and exercising more may pay dividends in terms of brain health, researchers determined.
Although not yet proven to thwart the cognitive decline that accompanies aging or dementia, the public should have access to this information, said Alan Leshner. He led the committee at the National Academies of Sciences, Engineering and Medicine that compiled the report.
"There are a few domains where the evidence that does exist suggests they might have an effect," said Leshner.
"At least two of those, we know, are good for a whole lot of other things that people do or that they could suffer from. That's controlling your blood pressure if you have hypertension and engaging in physical exercise," said Leshner, CEO emeritus of the American Association for the Advancement of Science.
Leshner's group was asked by the U.S. National Institute on Aging to research measures that might delay mild mental decline or Alzheimer's-like dementia.
Specialists welcomed the findings, which the researchers deemed encouraging even if not definitive.
"It's high time that people are given information about things they can do today to reduce their risk of cognitive decline and possibly dementia," said Keith Fargo, director of scientific programs and outreach at the Alzheimer's Association.
"Everyone is worried" about their mental functioning, he said. "But you shouldn't feel helpless. You should take control of your brain health," he added.
According to the report, which was released June 22, three promising areas for future research include:
He said the committee did not try to pinpoint which mental activities might be best; how low blood pressure should go; or how much exercise one needs to get the most benefit.
These are areas that need more research. Randomized trials are the "gold standard" of research and are the only ones that can prove or disprove a benefit from an intervention, he said.
One dementia specialist said some biological evidence supports the benefit of exercise, but in the final analysis, genetics might be the biggest determinant of whether you develop dementia.
"There is good evidence that physical exercise delays onset or slows progression [of dementia], perhaps because exercise stimulates release of nerve cell survival substances," said Dr. Sam Gandy. He directs the Center for Cognitive Health at Mount Sinai Hospital in New York City.
There is also good evidence that in people who carry the APOE4 gene mutation, which predisposes them to Alzheimer's, exercise can erase amyloid from their brains. Amyloid plaque is a hallmark of Alzheimer's disease, he said.
However, it's also possible that "genetic loading" for dementia is so strong in some people that diet and lifestyle will never be enough to prevent mental decline, he said.
Even without scientific backup for these lifestyle improvements, Leshner said they're worthwhile in their own right to improve other aspects of your health, such as preventing heart disease and strokes and improving the quality of your life.
"They're good for a whole bunch of other things," Leshner said.
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Lifestyle Changes Might Prevent or Slow Dementia - Twin Falls Times-News
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New genome sequencing method helps diagnose a rare genetic condition – Scope (blog)
Posted: at 5:47 am
When the race to sequence the human genome was reaching a fever pitch in the early 2000s, when I was in high school, I couldnt help but wonder, What comes next? Once we had full access to our genetic blueprint, what more was there to do?
As it turned out, the understanding of human genetics is much more complicated than Id imagined as a teen. And understanding how human health hinges upon the strings of molecular letters within our DNA isnt always easy, either.
Researchers at Stanford, in collaboration with the biotechnology company Pacific Biosciences, are working to push past some of the limitations of current sequencing technology. Their goal is to make full-genome sequencing accessible for clinical use. The team has used a new sequencing technology called long-read sequencing in a patient for the first time. I described their work in a press release:
Current sequencing technologies cut DNA into words that are about 100 base-pairs, or letters, long, according to the studys senior author, Euan Ashley, DPhil, FRCP, professor of cardiovascular medicine, of genetics and of biomedical data science at Stanford. Long-read sequencing, by comparison, cuts DNA into words that are thousands of letters long.
This allows us to illuminate dark corners of the genome like never before, Ashley said. Technology is such a powerful force in medicine, he added. Its mind-blowing that we are able to routinely sequence patients genomes when just a few years ago this was unthinkable.
In this study, which appears in Genetics in Medicine, the team used long-read sequencing to examinea part of Ricky Ramons genes that hadnt been successfully sequenced with current technology. Ramon, who is 26, has had benign tumors throughout his body since he was about 7 years old, but doctors couldnt pinpoint a diagnosis. Especially problematic were the tumors in Ramons heart, which required open-heart surgery to remove.
The team thought Ramons symptoms were indicative of Carney complex, an extremely rare genetic condition, but the sequencing method they used initially did not identify any changes to the gene responsible.
Carney complex arises from mutations in the PRKAR1A gene, and is characterized by increased risk for several tumor types, particularly in the heart and hormone-producing glands, such as ovaries, testes, adrenal glands, pituitary gland and thyroid. According to the National Institutes of Health, fewer than 750 individuals with this condition have been identified.
The most common symptom is benign heart tumors, or myxomas. Open heart surgery is required to remove cardiac myxomas; by the time Ramon was 18 years old, hed had three such surgeries.
The long-read sequencing gave Ramons team of doctors at Stanford a confirmed diagnosis of Carney complex, which allows them to make better-informed recommendations about his treatment.
Though having confirmation of a permanent genetic condition can be disheartening at times, Ramon told me: Im in good hands Im glad to be here.
Previously: Clinical guidance on genetic testing: A Q&A, New tool to ID disease-causing genetic changes developed at Stanfordand Mystery solved: Researchers use genetic tools to diagnose young girls rare heart condition Photo by MIKI Yoshihito
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New genome sequencing method helps diagnose a rare genetic condition - Scope (blog)
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A High School Pulled Its "Right-Wing Propaganda" Summer Reading List After Complaints – BuzzFeed News
Posted: at 5:47 am
Ponder ran an unsuccessful 2010 campaign for Alabama lieutenant governor as a Republican.
During the race, Ponder took a radical limited-government stance, and said in an email that he wanted to stop the federal government's "coercion, intimidation and blackmail" of states, according to AL.com.
He proposed that "all compulsory federal legislation that directs states to comply under threat of force by civil or criminal penalties or sanctions...be prohibited and repealed."
Local politicians from both sides of the aisle criticized Ponder's strong words. His Republican primary opponent, Hank Erwin, said "language like that" bordered on secessionist.
"We're not trying to secede from the Union," Erwin said at the time.
The mother, who asked her last name not be used, is a Democrat. Still, she said, she always taught her children to do "their own research, their own deciding on things."
But her teenage son hadn't really formed his own political beliefs before meeting Ponder, she said. And when he started the AP Government class, his sudden transformation was "scary."
"[My son] asked, 'Why shouldnt we be friends with Russia?' and 'Maybe dictatorship isnt so bad,'" said Jennifer. "He was never a racist kid. And he was a science buff."
She said she didn't complain to the school out of fear of retribution, and didn't see the reading list until it was posted online Wednesday.
"Now hes really argumentative, so we cant have good talks," said Jennifer. "Im never right, hes never wrong."
"I dont necessarily mind that he has his own mind, but this was implanted," she said. "This was purposeful by the teacher. It completely changed his ability to think about things on his own."
In a video he posted on Facebook, Morgan said the teacher is "a great Christian and a great human being" and "like a second father" to him.
He supports the reading list, but told BuzzFeed News he thinks it would be better if a few liberal books were added and students had to read one of each one liberal, one conservative.
"I don't think he purposefully tries to influence opinion, but I find that hard to believe because I actually shifted more left in his class than I originally was," Morgan said. "Before I went into his class I was far-right Republican, but now I am a libertarian. Fiscally conservative, socially liberal."
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A High School Pulled Its "Right-Wing Propaganda" Summer Reading List After Complaints - BuzzFeed News
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Chinese Authorities Crack Down on Streaming to Create a ‘Cleaner Cyberspace’ – TIME
Posted: at 5:46 am
The Weibo microblogging app displayed on an iPhone, April 22, 2014. Brent LewinBloomberg/Getty Images
China's media oversight body has ordered three major online companies to halt some of their multi-media streaming services, the government's latest move to tighten controls on an already restricted Internet.
Agence France-Presse reports that Sina Weibo the country's Twitter-like microblogging site with more than 340 million users as well as news sites iFeng.com and ACFUN, were informed they lacked permits required by the body to run audio-visual streams.
An announcement by China's State Administration of Press, Publication, Radio, Film and Television said the sites hosted "many politically-related programs that do not conform with state rules," and authorities are trying to "create a cleaner cyberspace," according to AFP.
Earlier this month another regulator, the Beijing Cyberspace Administration, ordered internet companies to terminate social media accounts that cater to "the public's vulgar taste" and disseminate celebrity gossip, AFP reports.
Willy Lam, a professor at Chinese University of Hong Kong's centre for China studies, tells TIME that Beijing has steadily tightened the screws on expression ahead of the Chinese Communist Party's 19th Congress, due to be held around October.
Lam says that Chinese President Xi Jinping " wants stability above all else in this sensitive period," but that ultimately censorship could backfire. " The more control of the media there is, the more ordinary Chinese tend to believe in speculation and innuendo," he says.
[ AFP ]
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Chinese Authorities Crack Down on Streaming to Create a 'Cleaner Cyberspace' - TIME
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Anti-Free-Speech Radicals Never Give Up – National Review
Posted: at 5:46 am
In the never-ending battle to preserve free speech, there is always good news and bad news. There are triumphs and setbacks. The struggle for liberty always encounters the will to power, and often the will to power is cloaked in terms of compassion, justice, and equality.
And so it is with the quest to censor so-called hate speech. First, lets address the good news. Earlier this week the Supreme Court ruled 80 against the U.S. Patent and Trademark Office (PTO), which had refused to register a trademark for a band called The Slants. The PTO claimed that the bands name violated provisions of the Lanham Act, which prohibits registering trademarks that disparage...or bring into contempt or disrepute any persons, living or dead.
As I wrote immediately after the decision, it would have been shocking if the Court hadnt ruled against the PTO. After all, there are literally decades of First Amendment precedents prohibiting the government from engaging in punitive viewpoint discrimination, even when the viewpoint expressed is deemed hatred or offensive. Justice Alito made short work of the notion that the government has an interest in preventing speech that expresses offensive ideas:
As we have explained, that idea strikes at the heart of the First Amendment. Speech that demeans on the basis of race, ethnicity, gender, religion, age, disability, or any other similar ground is hateful; but the proudest boast of our free speech jurisprudence is that we protect the freedom to express the thought that we hate.
But not even a ruling joined by Ruth Bader Ginsburg, Elena Kagan, and Sonia Sotomayor can persuade determined, far-left censors, and just as sure as night follows day, Laura Beth Nielsen, a research professor for the American Bar Foundation, took to the pages of the Los Angeles Times to make the case for viewpoint discrimination. Ive seen enough pieces like this to recognize the type. They always begin with misleading statements of the law, declarations that free-speech protections arent absolute, and then move to the core pitch in this case, that the state should regulate hate speech because its emotionally and physically harmful:
In fact, empirical data suggest that frequent verbal harassment can lead to various negative consequences. Racist hate speech has been linked to cigarette smoking, high blood pressure, anxiety, depression and post-traumatic stress disorder, and requires complex coping strategies. Exposure to racial slurs also diminishes academic performance. Women subjected to sexualized speech may develop a phenomenon of self-objectification, which is associated with eating disorders.
This is the very close cousin of the speech as violence argument sweeping campuses from coast to coast. Its the heart of the argument for the campus speech code that subjective listener response should dictate a speakers rights. The more fragile the listener, the greater the grounds for censorship.
And there is no limiting principle. If How does this speech make you feel? is the core question, it incentivizes victim politics and overreaction. Robust debate triggers robust emotions, and robust debate on the most sensitive issues issues like race, gender, and sexuality trigger the most robust of responses.
Lest anyone wonder about the actual definition of hate speech, look to campus and liberal activist groups. At Evergreen State College in Washington, a progressive professors statement against racial separation and division was deemed so hateful that he couldnt safely conduct classes on campus. Influential pressure groups such as the Southern Poverty Law Center label the Ku Klux Klan and other genuine racistshate groups but also apply the same label to mainstream Christian conservative organizations such as the Family Research Council. The SPLC has branded respected American Enterprise Institute scholar Charles Murray a white nationalist. Moreover, its far more forgiving of leftist extremism than of moderate speech that is conservative or libertarian.
In a stinging piece in the Wall Street Journal, Jeryl Bier notes the double standard:
Kori Ali Muhammad allegedly murdered three white people in California in April. The SPLC reports that on Facebook Mr. Muhammad wrote of grafted white devil skunks and repeatedly referred to the mythical Lost Found Asiaiatic [sic] Black Nation in America. Yet in contrast with its unequivocal (and false) tagging of Mr. Murray, the group describes Mr. Muhammad as a possible black separatist.
Got that? One of the Rights most important scholars stands condemned, while a man who shot and killed three people is just a possible separatist. Thats the through-the-looking-glass world of the anti-hate speech Left. The definitions are malleable, but one thing you can count on the Right will always lose.
Interestingly, the day before Nielsens call for censorship appeared in the Los Angeles Times, German police raided the homes of 36 people accused of hateful social-media postings. Thats where prohibitions against hate speech lead. Indeed, wannabe American censors often extol Europe as a model for their proposed American laws. Do you trust the government to decide when your viewpoint is unacceptable?
Left-wing censors discount voices like mine, claiming that its easy for me to pontificate on free speech while basking in my white privilege. Yet my family has been exposed to more vile and vicious rhetoric than most people will experience in ten lifetimes. Yes, its painful. Yes, it has consequences. But it is far more empowering to meet bad speech with better speech than it is to appeal to the government for protection even from the worst ideas.
To paraphrase Alan Charles Kors, co-founder of the Foundation for Individual Rights in Education, no class of Americans is too weak to live with freedom. Rather than indulging weakness and fear, activists left and right would do well to cultivate emotional strength and moral courage. The marketplace of ideas demands no less.
READ MORE: Free Speech Isnt Always a Tool for Virtue Speech Is Not Violence and Violence Is Not Self-Expression When Speech Inspires Violence, Protect Liberty While Restoring Virtue
David French is a senior writer for National Review, a senior fellow at the National Review Institute, and an attorney.
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Moves against Polish museum and Hungarian university stir fears of … – Christian Science Monitor
Posted: at 5:46 am
June 21, 2017 GDANSK, POLAND Housed in a $134-million, state-of-the-art building, Polands Museum of the Second World War opened early this spring. The museum, which took more than five years to construct, tells the story of Polands war experiences, which given the way the country is sandwiched between Germany and Russia are among the most tragic of all the conflict.
But even before the museum opened, it was already mired in controversy. The museums acting director, Karol Nawrocki hired when former director Pawel Machcewicz was fired, two weeks after the museum opened has complained that the exhibits about the rise of communism are too light, and the music is too happy, underplaying how deeply the political ideology inflicted damage on the Polish people.He has already indicated that he will be making changes to some exhibits.
In Hungary, meanwhile, it is a university that is in the sights of the government.Last week, students were busy finishing their spring term classes at Central European University, founded by American philanthropist George Soros. But even as faculty and students swarmed through the CEU buildings, clustered in the elegant heart of Budapest, a new law was taking aim at the Hungarian- and American-accredited university.
Both Polands Museum of the Second World War and Hungarys CEU one brand new, the other formed at the fall of communism have been seen as symbols of the advances in free thought and open societies in post-Soviet Europe. And the fact that both have become targets of their ruling governments is a sign, some critics say, of government attempts to control cultural and historic narratives and undermine academic freedom to consolidate political control.
The moves in central Europe hark back to an earlier era, in contrast to the anti-immigrant, anti-globalist nationalism taking root in western Europe, says Anton Pelinka, a professor of nationalism studies at CEU. The French nationalistic renaissance or German nationalistic renaissance is not about Alsace-Lorraine, says Professor Pelinka, referring to the historical land dispute. But Hungarian and Polish nationalism is very old fashioned. Taboos were perpetuated under communist rule, he says.But now, post-communist nationalistic regimes have created new taboos.
The war museum opened in March in the center of Gdansk, near a post office that was one of the first places Germans attacked the country during the war.It was commissioned in 2008 by then-Prime Minister Donald Tusk, today president of the European Council, and was intended to look at the war through an international lens. But the museum was barely open before the ultraconservative Law and Justice party (PiS) firedMr. Machcewicz and announced that some of the exhibits would change.
Mr. Nawrocki, the current director, says the museum the most expensive ever built in Poland has great potential. But I don't get [from the current exhibitions] the answer to a basic question what we Poles want to tell the world about our war experience, he says.
Poland suffered enormously in World War II, with 20 percent or more of its population killed,borders redrawn, and the war ending in communist rule. The new museum was not intended to diminish the Polish experience, says Machcewicz.But part of its purpose, he says, to tell a fuller story about the war, which may break ground for Poles, who havetended to cling to black-and-white ideas about victims and perpetrators.
One of the exhibits includes house keys that belonged to Jews in the village of Jedwabne, who were killed by their Polish neighbors with help from Nazis soldiers. The exhibits also spend time on atrocitiesperpetrated by the Soviet Union, as well ason the 3 million Russian soldiers who suffered in German captivity. The museum pushes Poles from the comfort zone, Machcewicz says, because we show how other nations suffered during the war.
Poles views are mixed, with some welcoming a new perspective, and others rejecting it. Kazimierz Burzynski, a retiree from Gdansk, says he is disappointed that there is not more about Poland in an educational center at the museum.But he also faults PiS opponents for politicizing the issue for political gain. [They are] discussing our issues abroad, involving foreigners in our discussion.
Internationally, the debate in Hungary has resonated even more widely.The Hungarian parliament passed a higher education law in April that effectively singles out the CEU, as it would require the school to open a campus in New York, where it is registered, or cease operations in Budapest.The university has announced that it will continue to operate in academic year 2017-2018, but its long-term future is now unclear. Negotiations between Hungary and the state of New York are expected later this month in an effort to find a solution before October, when the schools license to operate can be withdrawn under the new law.
The university was founded by Mr. Soros who was born in Hungary in 1991, with the stated intent of helping to usher in democracy in post-Soviet Europe. It has been operating in Budapest since 1993. Today CEU has over 1,400 students, including many who are seen as leaders in the region,and it is considered a major center of independent scholarship. But Hungarian Prime Minister Viktor Orban who has said that he sees illiberal democracy as the right path for Hungary says that the university has cheated by violating Hungarian rules, and that no institution should enjoy an unfair advantage.
For many observers, the new law has more to do with Mr. Soros as symbol of liberalism than with academic censorship.It is not about attacking academic freedom, its more like generating a conflict between the government and more pro-Western organizations or figures like George Soros,says Dniel Mikecz, an expert on social movements at the Republikon Institute. It is much easier to campaign with a scapegoat as enemy of the state. You dont have to raise the salaries of public servants, or introduce such benefits for the people.
Whatever Orbans motivations for moving against CEU, many observers fear its an open Hungarian society that is at stake. Orban has also clamped down on funding for NGOs and independent media, and rolled back checks and balances on the Hungarian constitution.
Globally, the fight over the CEU has stirred a firm response.
Two dozen Nobel laureates and academics and institutions around the world have declared support for the university. The law threatening its existence has been rebuked by the European Parliament, which started infringement proceedings against Hungary, prompting tens of thousands of protestors to the streets.I think free institutions and academic freedom strike a chord with a lot of people. It is a core democratic value. It is a core European value, says Michael Ignatieff, the president and rector of CEU.
For many of todays Europeans, its discomfiting to see politicians fighting for control of higher education and other cultural institutions. Machcewicz, a historian, says PiS views historic policy as one of its main pillars. He says the Polish government has set out to achieve control in ways that range from censuring art to announcing plans for new historic museums.
In rejecting our exhibition I see a growing anti-EU and xenophobic atmosphere, a rejection of Europe and multiculturalism, he says. While he says he sees a comparison between the Hungarian government's move against the CEU and the Polish government's decisions about his former museum, he characterizes Orbans move as a cynical power grab, while in Poland he suggests that something deeper is stirring. The Polish right wants power, too, but it is more ideological and radical, he says. The current government is striving for a cultural revolution in Poland.
Its not a direction that sits well with some Polish citizens. Sabina Woch is visiting the Gdansk museum with her 10-month-old son and her in-laws, eager to see the museums exhibits before the government makes any changes. World War II did not take place only in Poland or Europe, and its important to know what was happening in other continents, she says. Politicians should not decide who should run such institutions like a museum; its not their role.
Sara Miller Llana contributed reporting to this story from Paris.
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Moves against Polish museum and Hungarian university stir fears of ... - Christian Science Monitor
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National Coalition Against Censorship Chooses New Leader – Blogging Censorship
Posted: at 5:46 am
Chris Finan
CONTACT: Jas Chana, NCAC Communications Director jas@ncac.org, 212-807-6222 ext.107
New York, NY, June 21, 2017- The National Coalition Against Censorship (NCAC), an alliance of 56 national non-profit organizations, announced today that it has hired Christopher M. Finan as its next executive director. Joan Bertin, the current executive director, is stepping down after leading the organization for 20 years. NCAC promotes freedom of thought, inquiry and expression and opposes censorship in all its forms.
We are indeed lucky that a free expression advocate the caliber of Chris Finan has agreed to lead the NCAC to its next chapter, said Jon Anderson, chair of the NCAC Board of Directors and president and publisher of Simon & Schuster Childrens Publishing. In this most challenging of times for First Amendment rights, we need someone with the experience and reputation that Chris brings to the table in protecting the rights of all Americans to express themselves as they choose.
Finan has a long career as a free speech activist. He is currently director of American Booksellers for Free Expression, part of the American Booksellers Association (ABA). In 1982, he joined Media Coalition, a trade association that defends the First Amendment rights of booksellers, publishers, librarians and others who produce and distribute First Amendment-protected material. In 1998, he became president of the American Booksellers Foundation for Free Expression. The foundation merged with ABA in 2015.
Finan has worked closely with NCAC as a member of the board of directors and as a board chair. In 2007, he and Bertin created NCACs Kids Right to Read Project, which supports parents, students, teachers and librarians who are fighting efforts to ban books in schools and libraries.
I am very grateful for the opportunity to lead an organization that plays such an important role in protecting free expression. I am also very fortunate to be succeeding Joan Bertin, who has led NCACs vigorous defense of free speech during a time of growing censorship pressure, Finan said.
As examples of NCACs recent advocacy, Finan pointed to statements defending publishers who are pressured to censor books that some critics consider offensive, condemning the Trump administrations attacks on the press and criticizing the Walker Art Centers decision to dismantle a sculpture after accusations that it was cultural appropriation.
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National Coalition Against Censorship Chooses New Leader - Blogging Censorship
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Four Senate Republicans oppose draft of GOP health plan - Washington Times
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