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Daily Archives: June 26, 2017
Meet the horsemen of our environmental apocalypse – Salon.com – Salon
Posted: June 26, 2017 at 4:47 pm
Consolidation of power by the oil and coal barons began immediately after the election; president-elect Trumps transition advisors emerged as an oil industry dream team. Despite the initial antipathy between Trump and the Koch brothers, once he secured the nomination, Donald Trump extended the olive branch to the flat earth oligarchs from Kansas. His choice of Indiana Governor Mike Pence as running mate was the first ominous sign that the rift had healed. Governor Pence had financed his political career with a steady flow of Koch cash and had demonstrated his fealty to the Kochs by hiring Marc Short as his gubernatorial chief of staff. Short had previously been president of Freedom Partners, the Kochs political arm. As governor, Pence made Indiana a proving ground for the radical right-wing experiment in corporate domination devised by Koch-funded think-tanks.
Three days after the 2016 election, Pence displaced New Jersey Governor Chris Christie to become Trumps overseer of the various agency transition teams. By that time, the writing was on the wall, and the penmanship was that of David and Charles Koch. David Koch attended Trumps election night celebration. Trump soon appointed Marc Short as his director of legislative affairs, and stocked his transition team with Koch organization veterans, such as Tom Pyle, Darin Selnick, and Alan Cobb, and transition team executive committee members, Rebekah Mercer and Anthony Scaramucci. According to The Wall Street Journal, an astonishing 30 to 40 percent of Trumps advisors had Koch pedigrees. These were the men and women who would shape the new presidents agenda.
Trump appointed a notorious Koch toady, Myron Ebell, to supervise his EPA transition. Ive watched Ebells antics for decades. He is a professional deceiver. Ebell served as director of the Center for Energy and Environment at the Competitive Enterprise Institute, a Washington think-tank formerly funded by ExxonMobil and the Kochs, and staffed primarily by experts and operatives, lately employed by Koch Industries and the Kochs web of shadowy non-profit oil industry advocacy groups. Ebell, once a staunch global warming denier, has recently retrenched; Yes, we are causing climate change, he now admits, but its a good thing. Ebell preaches that the mild global warming that has occurred since the end of the Little Ice Age in the mid-nineteenth century has been largely beneficial for humanity and the biosphere. Earth is greening, food production has soared, and human longevity has increased dramatically.
Ebells seven-person team included David Schnare, a lawyer who spent thirty-three years at the EPA before matriculating to institutes funded by the Kochs. Schnare made his bones as a polluters shill by filing legal actions demanding to inspect the email inboxes of EPA administrators and climate scientists. In Trumps new era of alternative facts, there was no one better suited to purge the agency of credulous climate change believers.
Steve Groves led the State Departments landing team. Groves, a policy wonk at the Koch- and Exxon-funded Heritage Foundation, wrote a post-election article calling for the United States to pull out of the United Nations Framework Convention on Climate Change as a prelude to refuting the Paris Agreement.
The Department of Interior transition fell under the leadership of Doug Domenech, director of the Fueling Freedom Project for the Koch-funded Texas Public Policy Foundation. That groups mission is to explain the forgotten moral case for fossil fuels. Domenech knows how to make the system work for industry; during George W. Bushs presidency, he served as White House liaison and deputy chief of staff at the Interior Department, facilitating Bushs efforts to turn federal lands over to oil, gas, and mining interests and to timber barons.
President Trumps transition overseer at the Department of Energy was Michael Catanzaro, a registered Koch Industries lobbyist. His successor is Thomas Pyle, former president of the Institute for Energy Research, a think-tank founded by Charles Koch. Before joining that chamber for charlatans, Pyle was Koch Industries director of federal affairs. Pyle is also president of the American Energy Alliance, another fossil fuel front group that receives a pipeline of cash from Koch, ExxonMobil, and Peabody Energy. (Youll learn much more about the Peabody CEO in Chapter 7 of this book.)
Pyle mapped out a big change in an email to supporters in mid-November. He promised a 100-day plan and a 200-day plan to roll back Americas clean water and climate change protections. America, he promised, will pull out of the Paris Climate Agreement, and the EPA will jettison the dreaded social cost of carbon algorithm used to calculate the costs and benefits of climate change.
In December, eight hundred US scientists and energy experts sent a letter to president-elect Trump asking that he publicly identify global warming as a human caused, urgent threat. They went on: If not, you will become the only government leader in the world to deny climate science. Your position will be at odds with virtually all climate scientists, most economists, military experts, fossil fuel companies and other business leaders, and the two-thirds of Americans worried about this issue. Trump answered this urgent plea by the worlds most highly credentialed climate scientists during a Fox News interview in mid-December, assuring the audience that nobody really knows whether climate change is real. He said he was studying whether to pull America out of the Paris Climate Agreement, the hard-won treaty to reduce greenhouse gas emissions that has been signed by 196 countries. There is little doubt about who is providing him crib-notes.
The ominous direction toward global catastrophe crystallized as Trump announced his cabinet and other key positions.
SECRETARY OF STATE: REX TILLERSON
And I looked, and behold a pale horse; and his name that sat on him was Death, and Hell followed with him. And power was given unto them over the fourth part of the earth, to kill with sword, and with hunger, and with death, and with the beasts of the earth. Revelation, 6:8.
In a breathtaking act of supplication to Big Oil, the new president gave his first cabinet appointment to Russells first Horseman, ExxonMobil CEO Rex Tillerson. Tillerson has never been mistaken for an American patriot. As Exxon CEO, he often adopted company policies that were contrary to US interests, including a lucrative deal with Russia to drill in the Arctic. When a shareholder asked Tillersons predecessor and mentor, Lee Raymond, whether the company should be improving US refinery capacity as a matter of national security, Raymond dismissed patriotism as an absurd distraction from profits. He famously declared, Exxon is not a US company. Tillersons worldview is dictated by his forty years of service to the selfish ideologies of a corporation that is locked in a ruinous battle against humanity and American values.
Trumps critics wondered whether his peculiar choice to hand US foreign policy over to the worlds most visible and notorious oil man was a favor to Russian dictator Vladimir Putin. As Exxon chief, Tillerson put aside scruples to align Exxon with the bloodthirsty tyrant, a choice that made Tillerson Putins favorite American businessman. In 2013, Vladimir Putin personally presented Tillerson with Russias ultimate honor to a foreigner, the Order of Friendship Award, after Tillerson signed controversial deals with the state-owned Russian oil company. In 2011, Tillerson flew to Russia to sign a $500-billion arrangement to jointly drill in the Arctic Shelf and the Black Sea and to develop shale oil in Siberia. Tillersons company allegedly lost around $1 billion dollars due to sanctions the Obama administration placed on Russia after Putin annexed the Crimean Peninsula.
Tillerson responded by directing ExxonMobils PAC to donate $1.8 million to oil-friendly federal politicians during the 2016 election cycle, with more than 90 percent going to the Republicans, who had dutifully shielded Exxon from carbon taxes and pollution regulations. During the six election cycles when he was CEO, nine of ten dollars donated by his companys PAC went to GOP candidates.
Exxons corporate culture is not an admirable template for American idealism. Exxon already is a petro-state, wealthier than most countries, with its own private armies and intelligence apparatus. Now the head of Exxon is running our foreign affairs, with access to the many intelligence services and the capacity to bully states who dont tow the oil line.
Waterkeeper Alliance is a clean water advocacy group, of which I serve as president. Waterkeeper, which works in thirty-eight countries, has submitted a fifty-four-page petition to the EPA calling for the agency to enforce bad corporate actor rules and end all its federal contracts with ExxonMobil. The petition addresses Exxons decades of deliberate liesthe companys campaign to deceive the public, politicians, and regulators about the danger of climate change. Recently-released documents prove that the sociopaths, including Tillerson, who ran Exxon knew for decades that its business activities would cause catastrophic climate change and mass death. Putting profits before people, Exxon kept its climate change science secret, while funding professional liars and nurturing the growth of a generation of climate change deniers. Under Rex Tillersons leadership, the company continued to push government policies that buck proven science, human welfare, national security, and fundamental moral, ethical, and religious tenets. Last year, Exxon claimed as assets $330 billion in underground oil reserves that include some of the dirtiest fuels on Earth. The Securities and Exchange Commission and several states attorneys general, led by New Yorks Eric Schneiderman, are currently investigating Exxons failure to disclose to its stockholders the risks it has long known are posed to company value by the reality of global warming. According to Schneiderman, unless we are willing to write off planet Earth, about two-thirds of those reserves can never leave the ground. Exxon is therefore exaggerating its market value by hundreds of billions.
Tillerson has never expressed concern or even the slightest self-awareness that Exxons business model threatens the future of humanity and life on Earth. Americas largest oil company has accounted for more than 3 percent of global climate pollution, dating back to the mid-1800s. After years of putting Exxons stock value ahead of humanity, will Tillerson now put America and the planet first? Tillersons company would be severely impacted by the Paris Climate Accord to limit the burning of fossil fuels. His thoughts on climate change? What good is it to save the planet if humanity [read Exxon] suffers.
And Tillerson didnt waste any time as head of the State Department to scrub the website of the Office of Global Change to reflect his stance. As noted by the Environmental Data and Governance Initiative, the revised website removed any mention of President Obamas Climate Action Plan to reduce carbon pollution, promote clean sources of energy that create jobs, protect communities from the impacts of climate change and work with partners to lead international climate change efforts.
THE ENVIRONMENTAL PROTECTION AGENCY: SCOTT PRUITT
These have power to shut heaven, that it rain not in the days of their prophecy: and have power over waters to turn them to blood, and to smite the earth with all plagues, as often as they will. . . . And men were scorched with great heat. . . . And every island fled away, and the mountains were not found. Revelation, 11:6, 16:9,20
Trumps choice to run the EPA is an unctuous acolyte of Oklahomas factory meat and Big Oil barons. Scott Pruitt built his career as a patsy for polluters: Prior to Pruitts election in 2010, the Oklahoma attorney generals office had built a model environmental enforcement division under Kelly Hunter Foster, who is now a staff attorney for my organization, Waterkeeper Alliance. Foster had filed a dozen lawsuits against the poultry and industrial pork industries, which were polluting Oklahomas air and waterways, sickening its citizens with effluvia of factory meat production, and putting family farmers out of business. Pruitt was the chicken industrys handpicked attorney general. Oklahomas corporate meat barons financed Pruitts campaign to rid themselves of Fosters lawsuits. Once in office, Pruitt dutifully terminated Hunter Fosters unit and shelved her docket. As attorney general, he never filed another environmental action. Instead, Pruitt turned his offices big guns against the EPA, filing a battery of federal lawsuits against the agency to challenge the Obama administrations anti-pollution and climate safeguards. These included suing the EPA to block the Clean Power Plan and another suit aimed at gutting rules on methane emissions from the oil-and-gas sector. He let polluters off the hook and destroyed a decade of work, recalls Hunter Foster. He has no environmental experience and no conservation instincts. His only qualification for his new job was his fierce hatred for EPA. Since his ascension to the administrators post, Pruitt has frozen all new permits and scientific studies and put the agency in lockdown. He has promised to lay off 3,000 of the 15,000 EPA workers and cut the agencys already anemic budget by 31 percent, more than any other agency.
And the merchants of the earth are waxed rich . . . for thy merchants were the great men of the earth; for by thy sorceries were all nations deceived. Revelation, 18:3,23
Calvin Coolidge famously remarked that the chief business of the American people is business. Trump has made it clear that business is to be the EPAs business as well. Pruitt burnished his resume for the EPA post with a major push by his mentor, Carl Icahn, a billionaire Wall Street hedge fund titan and generous Trump campaign donor. Icahns holding company does business with the Koch brothers and TransCanadas Keystone pipeline system. A noisome EPA had accused Icahns Oklahoma-based oil company of violating environmental laws. Based on these qualifications, Trump appointed Icahn to vet the contenders for the top-level EPA jobs.
Pruitt also received a boost from another of the Horsemen featured in this bookOklahoma billionaire Harold Hamm (see Chapter 6). Hamm chaired Pruitts 2013 reelection campaign. During the 2016 presidential election, Hamm had served as candidate Trumps energy advisor, but declined the president-elects offer to head the Department of Energy.
Pruitt also boasts a direct Koch connection; as Oklahoma attorney general, Pruitt was simultaneously a director of the nonprofit Rule of Law Defense Fund, which received $175,000 in 2014 from a dark money umbrella group called Freedom Partners, the Koch networks political arm.
President Trump evidently shares Pruitts antipathy toward the environmental agency. Upon announcing Pruitts appointment, Trump added, For too long, the Environmental Protection Agency has spent taxpayer dollars on an out-of-control anti-energy agenda that has destroyed millions of jobs. In mid-March, the president announced that hed ordered Pruitt to revise one of President Obamas primary climate change policiesthe EPAs strict standards on tailpipe pollution from motor vehicles. As to climate change, Trumps director of the Office of Management and Budget said at a White House briefing, I think the president was fairly straightforward; Were not spending money on that anymore.
On March 2, Pruitt told CNBC News with his characteristic dumb as I wanna be glee that humans were not responsible for global warming. Pruitt was proudly jockeying the EPA into position as the flagship of the new administrations anti-science crusade. The Bush administration had regarded science as a vanity of the despised liberal elite. One anonymous White House official, speaking to investigative journalist Ron Suskind, famously disparaged the liberal obsession with science-based inconvenient truths like climate change as fact-based reality. But the Trump clown team has immediately achieved a new dimension of unhinged, by appointing a science-hating flat-earther as head of the worlds premier environmental agency.
Even Christie Todd Whitman, who presided over the gutting of the EPA under George W. Bush from 2001 to 2003, was sickened by Pruitts appointment. I dont recall ever having seen an appointment of someone who is so disdainful of the agency and the science behind what the agency does.
Pruitt will have help from above as he plows under the rubble of his despised agency. In late December, Trump named Carl Icahn to a new administration position created by the president: Special Adviser on Regulatory Reform. While the administration proceeded to freeze adopting other new regulations, Icahn quickly succeeded in obtaining a special IRS rule that gives a tax break to his oil-refining company, CVR Energy. Icahn is simultaneously pushing for a regulatory fix that would revamp an EPA rule (the Renewable Fuel Standard), which currently makes refiners responsible for ensuring corn-based ethanol is properly mixed into gasoline. Eliminating that requirement would have saved his company more than $200 million last year. Icahn, whose $16.6 billion is a fortune larger than all the other cabinet members combined, claims immunity from such conflict-of-interest problems because hes simply an unpaid adviser to the administration.
SECRETARY OF INTERIOR: RYAN ZINKE
And there followed hail and fire mingled with blood, and they were cast upon the earth: and the third part of trees was burnt up, and all green grass was burnt up. . . . And the third part of the creatures which were in the sea, and had life, died. . . . And the sun and the air were darkened by reason of the smoke of the pit. Revelation, 8:7,8, 9:2
My friend, Leonardo DiCaprio, a leading climate activist, gave a presentation to Trump soon after the election. He and DiCaprio Foundation president Terry Tamminen, the former Santa Monica BayKeeper and chief of California EPA under Governor Arnold Schwarzenegger, unveiled a plan for creating millions of jobs by encouraging the growth of clean, renewable energy. Looking at the plan approvingly, president-elect Trump told Leo that he wanted to be the twenty-first-century Teddy Roosevelt. Leo gave him a copy of his new documentary Before the Flood describing the perils of climate change, and the president-elect promised to watch it. Afterward, Leo learned that Trumps team had announced the appointment of Scott Pruitt, while they were still in the meeting. Trump had warned Leo, There are going to be some you will consider bad appointments. But, he promised the actor, Youre really gonna like who we put in for Interior.
That environmental superhero turned out to be Ryan Zinke, a first-term congressman from Montana who also describes himself as a Teddy Roosevelt guy. But while Roosevelt dismantled Standard Oil, Zinke has spent his career suckling at the industry teat, gagging down $345,136 of oily money from petro interests. In the House, Zinke represented the Powder River Basin, a once edenic wilderness, transformed into a moonscape by federal coal-leasing policies, championed by Zinke. In fact, in recognition of his enthusiasm as a cheerleader for coal extraction, the League of Conservation Voters awarded Zinke a 3 percent score. In 2008, Zinke said he believed in climate change, but has since dutifully recanted, in goose-step with the Republican Party leadership. It isnt proven science, he now insists.
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Meet the horsemen of our environmental apocalypse - Salon.com - Salon
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Do newborns need moisturizer? – Miami Herald
Posted: at 4:47 pm
Miami Herald | Do newborns need moisturizer? Miami Herald Parents who have older children with eczema or other similar skin conditions might want to consider moisturizing their newborn's skin because atopic dermatitis has a genetic component and runs in families. The use of moisturizer beginning in the ... |
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Do newborns need moisturizer? - Miami Herald
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Yes, There’s a Miracle Trick to Relieve Eczemaand It’s Unbelievably Simple – Reader’s Digest
Posted: at 4:47 pm
Leszek-Kobusinski/Shutterstock, Olga-Vorontsova/ShutterstockIve suffered with eczema for over 20 years. From my first year of life, the dry, scaly skin was all too familiar; every night, I would go through a nighttime routine of slathering greasy ointments and creams until the chunky layer of lotion became a whole other skin to me. The idea of short-sleeve shirts sent a shiver down my spine, and I often resorted to sweaters and jackets in 90 degree weather. When I was a kid, I even had to attend school with bandages wrapped around my inner elbows to prevent bleeding.
The perpetual itch lingering on my skin was like having a series of mosquito bites you can never scratch; do it and it just gets worse. Needless to say, it was not a pleasurable condition and Idid all Icould do to relieve it.
Fun fact: Pretty much every dermatologist you visit will look you sternly in the eyes and tell you there is no cure for eczema; its a chronic condition that youll just have to learn to live with. (Learn more about what common diseases you skin can reveal.) This is definitely not what anybody wantsto hear becauseits partly truethere is no official treatment or magical antibiotic you can swallow to completely eradicate those red patches. But fear not: there are several remedies that can come pretty close.
After speaking with several different doctors, I was told to try the topical steroid hydrocortisone at an early age. Hydrocortisone is no foreign substance to eczema sufferersthe famed medication is commonly used to treat redness, swelling, and itching, so eczema symptoms fit its usage to a T. Unfortunately, relief is oftentimes temporary, and frequent application is highly discouraged for its strong chemicals.
I wanted something that would last longer, work quicker, and treat better. Several fellow eczema sufferers proclaimed the beauty of aloe and its ability to work wonders. At the same time, my doctor informed me that using too many different eczema treatments in conjunction with one another can actually be less effective, so I dropped the army of dermatitis tubes and oatmeal scrubs sitting on my counter and replaced it with just two: aloe and hydrocortisone.
This combination worked wonders for me; using aloe alone was not effective and using hydrocortisone itself was not long-lasting. The mixture of the two, however, was able to not only soothe my nagging itch, but expunge the scaly patches entirely.
Dr. Loretta Ciraldo, a Miami-based board certified dermatologist, offered up some insight as to why this can work. As a general guideline, itchy eczema skin should be kept cool. Cortisone 10 ointment is usually very helpful as it hydrates skin while delivering 1 percent hydrocortisone which had previously been available by prescription only. Together, the combination of hydrocortisone and aloe vera brings cooling relief to the skin, saysCiraldo.
Although raw aloe works best, we know it may not be ideal to start growing a garden of aloe plants on your windowsill. If you happen to do so, break open the thick part of the leaf and apply the gel directly onto the affected area. Otherwise, organic aloe fromyour local drugstore should do the trick just fine.
Keep an eye out for creams that combine the two elements into a single treatment; the one that I use from Equate is my holy grail go-to.
The treatment should only be applied to clean, freshly washed skin; directly after a shower is most ideal as it opens up your pores for easy absorption. From personal experience, applying ointment to dirty skin can aggravate your eczema even more, so keep the application strictly to the bathroom.
To maximize results, soak skin think of staying in a room temperature shower until your fingertips get all wrinkled, saysCiraldo. At this point your skin has replenished water levels back into the dry, eczema-affected skin. Pat dry and apply the 1 percent cortisone ointment to your skin while it is still damp.
Keep in mind that everybodys skin is different, so what worked for me might not work for the next guybut the combo is definitely worth a try to those yearning for some instant effects.
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Yes, There's a Miracle Trick to Relieve Eczemaand It's Unbelievably Simple - Reader's Digest
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5 Things People With Eczema Don’t Want to Hear From You – Health.com
Posted: at 4:47 pm
Eczema, a skin condition that causes red, itchy rashes, affects over 30 million people in the United States. Because the symptoms of eczema can be so visible, many people with this condition regularly hear frustrating comments. Whether its stares from a stranger or well-intentioned advice from that friend who thinks they have a medical degree, people with eczema are often on the receiving end of insensitive questions. In this video, we share five things you should never say to someone with eczema.
One of the most common questions eczema patients will get is whether or not their condition is contagious. The answer? No. While experts dont know the exact cause of eczema, genetics and environment are thought to play a role. So go ahead, give a friend with eczema a hug.
RELATED: The Best Ways to Cope With Eczema on Your Face, According to Dermatologists
Next, try to stop yourself from saying, At least its not While its true that eczema isnt life-threatening, it can be a serious burden. People with eczema need to be extremely careful about coming in contact with potential allergens, household chemicals, and even extreme weather, all of which may exacerbate symptoms. Itchy rashes can also keep people with eczema up at night and impact their relationships.
Watch the video:What Its Like to Live With Eczema, According to Someone Who Has It
Another piece of advice to avoid giving? You should use antibacterial soap. For one thing, eczema isnt the result of a lack of cleanliness. Plus, the product can actually aggravate, rather than alleviate, symptoms, experts say.
Finally, if youre not a specialist, steer clear of suggesting medications to your friends with eczema; most people have already tried many MD-recommended treatments and are aware of what works for their skin (and what doesnt). And dont draw attention to someones eczema flare-upever. OMG! Were you in a fire? What happened to you? is never a kind thing to say.
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5 Things People With Eczema Don't Want to Hear From You - Health.com
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The Solution for Skin Ailments Could Be Right Under Your Nose – New York Times
Posted: at 4:47 pm
Next they applied the experimental balm to the volunteers forearms, drastically increasing the numbers of their own helpful skin bacteria. Within 24 hours, the probiotic lotion nearly eliminated S. aureus from their skin. The researchers were also able to identify some of the compounds that the beneficial bacteria use to deter S. aureus.
Dr. Gallo and his collaborators published their results earlier this year in Science Translational Medicine.
Its the first time anything like this has been shown, said Elizabeth Grice, a research dermatologist and microbiologist at the University of Pennsylvania who was not involved in the experiment. What remains to be seen is whether this kind of treatment can reduce the severity of skin disease over the long term.
Only in the last few years have scientists seriously studied how to therapeutically modify the skins native colonies of microbes. Understanding this unique microbiome may yield new ideas for treating various dermatologic conditions.
Some studies suggest, for example, that people prone to acne carry more of the microbe Propionibacterium acnes on their skin. A disturbance in typical bacterial populations leads to conflict between P. acnes and neighboring species, the theory goes, which in turn triggers an inflammatory response in the skin.
In another study published late last year, Dr. Gallo and his colleagues injected a beneficial strain of Staphylococcus epidermidis, along with some food that only it could digest, into the ears of mice. The combination treatment, known as a synbiotic, encouraged the growth of S. epidermidis, which in turn reduced both the number of P. acnes and level of inflammation in the mice.
Other scientists have been reporting similar findings. In 2014, a team in South Korea and the United States showed that an extract from Helicobacter pylori a common resident of the human stomach also can inhibit P. acnes and decrease skin inflammation in mice.
Scientists in Canada have demonstrated that people who take both probiotics and antibiotics have significantly fewer acne lesions after 12 weeks, compared with people who take only one or the other.
Several private companies are racing to capitalize on a growing consumer appetite for probiotic cosmetics, toiletries and topical treatments. The biotech company AOBiome offers a live probiotic spray, for instance, that is meant to replenish populations of beneficial skin bacteria.
Many microbiologists worry, however, that the science is nowhere near advanced enough to justify the proliferation of these products. Scientists still have a lot to learn about what microbial ecosystems look like on healthy skin, how they change during illness, and how to safely interfere.
Topical probiotics can easily rub off and be transferred to other parts of the body or other people, Dr. Grice pointed out. Just because a microbe kills one species of pathogen does not mean it is unwaveringly good or peaceful.
And what if the bacteria in a lotion or spray were to infiltrate the body via a cut or scratch?
Dr. Grice agreed, however, that the idea is intriguing. Whereas typical antibiotics and antiseptics indiscriminately kill all kinds of bacteria throughout the body and drive the evolution of highly dangerous microbes impervious to existing drugs, probiotics may be much more selective.
And probiotics that successfully colonize the body have the unique ability to evolve in concert with a surrounding ecosystem. After all, genuine microbe-based therapies are not just cocktails of molecules; they contain living organisms that persist and adapt. Dr. Gallo calls his experimental lotion an evolutionarily honed treatment.
There are so many new potent medicines right under our nose, he said.
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The Solution for Skin Ailments Could Be Right Under Your Nose - New York Times
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8 Celebrities on How They Cope With a Serious Health Condition – Health.com
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If you struggle with a health condition, its important to remember that youre not alone. In fact, many celebrities have dealt with serious health problems such as endometriosis and multiple sclerosis. And many of these A-listers have taken advantage of their public positions to speak out about their illness in an effort to help end any stigma surrounding it, as well as offer support to others facing similar challenges. In this video, see eight inspiring stars who have opened up about what its like to live with a serious health condition.
Watch the video: 6 Tricks to Stop Scratching if You Have Eczema
No time to watch? Check out a collection of their quotes below:
Sarah Hyland
After having a kidney transplant in 2012 for kidney dysplasia, she spoke up about dealing with body-shamers: I dont mind when you say that I look pregnant. Or fat. Because I know that my face is swollen from my medication that is saving my life. For those on prednisone I know what youre going through and I commend you sticking it out as I have. @Sarah_Hyland, 2017
Lena Dunham
After being hospitalized due to complications from endometriosis: I also want to remind all the women suffering from chronic illness that we aren't weak- quite the opposite, actually. We do our jobs with skill even when we're struggling.[E]veryone who's anyone knows that if you can battle chronic illness there's nothing you can't take on. @lenadunham, 2017
Watch the video: What It's Like to Live With Eczema, According to Someone Who Has It
Padma Lakshmi
On endometriosis: Endometriosis was definitely a major reason that my marriage failed. I dont think either of us understood it at the time. I think thats also because I hid it to a certain degree. Entertainment Weekly, 2016
Susan Sarandon
On endometriosis: Suffering should not define you as a woman, and just because youre a man it doesnt mean that it does affect you! Endometriosis Foundation of America Blossom Ball, 2009
Kim Kardashian
On psoriasis: I have that one patch on my right leg that is the most visible. I dont even really try to cover it that much anymore. Sometimes I just feel like its my big flaw and everyone knows about it, so why cover it? After this many years, Ive really learned to live with it. Kardashians app, 2016
Watch the video: 5 Things Someone With Eczema Wants You to Know
Jamie Lynn Sigler
On multiple sclerosis: When I walk, I have to think about every single step, which is annoying and frustrating.Its part of me, but its not who I am. People, 2016
Robin Roberts
On learning that she landed an interview with Barack Obama (that would occur the following day) on the day she endured a painful bone marrow extraction for the blood condition myelodysplastic syndrome: [It] reminds me that God only gives us what we can handle and that it helps to have a good sense of humor when we run smack into the absurdity of life.ABC News, 2013
Halle Berry
On living with type 1 diabetes: I became much healthier as I learned how to manage it. It took a couple of years, and some scary situations, to accept that it was a lifestyle change and not a diet I could stop in six months. LA Times, 2015
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8 Celebrities on How They Cope With a Serious Health Condition - Health.com
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Sunlight could be key to eczema relief – InDaily
Posted: at 4:47 pm
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London Monday June 26, 2017
Exposure to sunlight releases a compound from the skin that can alleviate symptoms of eczema, research has found.
The molecule, called nitric oxide, works by dampening inflammation, which causes itchy skin associated with the condition.
Scientists say their findings pave the way for new therapies which mimic the effects of the suns rays and could help patients avoid light therapy, which can have damaging side effects on the skin such as raising cancer risk.
Lead researcher Dr Anne Astier, of the Medical Research Council Centre for Inflammation Research at the University of Edinburgh, said: Our findings suggest that nitric oxide has powerful anti-inflammatory properties and could offer an alternative drug target for people with eczema.
Tests on healthy volunteers found that exposing a small patch of skin to UV light triggers a release of nitric oxide into the blood stream.
Further studies found the chemical activates specialised immune cells called regulatory T cells, which act to dampen ongoing inflammation.
The University of Edinburgh team found patients with eczema saw the increased number of these cells in their blood following light therapy fitted with disease improvement.
Researchers say their findings could lead to new therapies for the condition, which affects around one in five children and one in 20 adults in the UK.
People with severe forms are often prescribed tanning lamps to help manage their symptoms, but these can cause skin burning, accelerated ageing and increased risk of cancer.
Professor Richard Weller, senior lecturer in Dermatology at the University of Edinburgh, said: It is clear that the health benefits of sunlight stretch far beyond vitamin D and we are starting to fill in these blank spaces.
The study is published in the Journal of Allergy and Clinical Immunology.
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Local Clinical research could give more options for patients suffering from psoriasis – WTSP 10 News
Posted: at 4:47 pm
Local research study could help psoriasis patients
Shannon Valladolid, WTSP 11:32 PM. EDT June 25, 2017
Imagine living with a skin condition that leaves severe rashes all over your body.
We're talking about Psoriasis.
For years, people suffering from the condition had only one option to get rid of it, painful weekly injections.
For the past 8 years, Olga Clark has given herself two injections every week to treat her Psoriasis.
I couldn't take a bath because the water burned my skin. My scalp was really severe to where I would scratch and I felt like I was bleeding, says Clark.
She no longer has rashes on her skin, now but Olgas says at its peak, psoriasis took over her body.
There was not a spot on me that was clear. my legs were covered, everything was covered, says Clark.
In 2014, the first pill finally hit the market called Otezla.
In an effort to challenge the only that pill, Dr.Seth Forman, who is the Principal Investigator with Forward Clinical Trials, is conducting a local research study to put a new pill in the hands of patients like Olga.
Olga is one of hundreds of patients that I have on these injectable medications. I can tell you most, if not all would rather take a pill like they do for their cholesterol or their blood pressure, says Dr.Forman, MD.
Dr. Forman says the downside to only having one pill option is some patients could have an allergic reaction, then it's back to injections. That's why he says clinical research is so important.
In order for us to get there for other skin conditions like Psoriasis, eczema. The only way we can do that is by having these what I call heroes participate in clinical research, he says.
Giving people living with severe skin conditions, an option to possibly not feel the pain of a needle.
If it didn't have to take a shot I would be happy. For them just to get on a pill, I think that's going to be great for them, says Clark.
Otezla has mixed reviews. Some complain they have severe side effects. But others say its really helped them deal with their condition.
Forward Clinical Trials is also working on research studies for treating the following:
To learn more regarding these studies or how you can get involved click here.
2017 WTSP-TV
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Local Clinical research could give more options for patients suffering from psoriasis - WTSP 10 News
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Adalimumab Safe and Effective Therapy for Pediatric Psoriasis – Medical News Bulletin
Posted: at 4:47 pm
As an inhibitor of an inflammatory protein associated with the development of psoriasis, adalimumab shows promise as a therapy for pediatric patients with severe plaque psoriasis. Adalimumab treatment for 16 weeks in children and adolescents with severe plaque psoriasis provides significant improvements compared to methotrexate.
Psoriasis is a chronic skin condition characterized by scales and red patches that are typically found on the scalp, elbows, and knees. This buildup of extra skin cells on the surface of the epidermis is an autoimmune inflammatory disease, which is currently incurable. Immune system T-cells and an abundance of inflammatory protein tumor necrosis factor-alpha (TNF-) play major roles in the development of psoriasis. Though there are many types of psoriasis, plaque psoriasis is the most common condition which involves the build-up of plaque on the surface of the skin. Itching, burning, soreness, or cracked skin are some of the symptoms associated with the disease and its severity can be classified as mild, affecting less than 5% of the skins surface area, moderate, affecting 5 to 10% of the skin, or severe, with more than 10% of the skins surface affected. Affecting 2% of the general population, a third of psoriasis diagnoses made by physicians include those who are 20 years of age and younger.
Management of pediatric psoriasis can decrease the risk of psychosocial issues and comorbidities such as, hypertension and diabetes. Initial treatment for patients with limited disease includes topical therapies, while severe pediatric psoriasis is treated using ultraviolet B phototherapy, or systemic treatments, such as methotrexate, ciclosporin, or retinoids. However, though TNF- inhibitor, methotrexate, has been prescribed to treat children and adolescents, it has not been approved by the European Medicine Agency, thus making it a good candidate for clinical research assessment. Due to the lack of standardized guidelines and approved systemic therapies, managing psoriasis by the blockage of TNF-, has been challenging. However, in 2015, TNF- inhibitor, adalimumab, was approved in the United States to treat severe cases in patients who were 4 years of age and older, and who did not respond adequately to topical therapy or phototherapies. Therefore, it is important to compare both inhibitors for their safety and efficacy in treating severe pediatric plaque psoriasis.
A double-blind randomized controlled study was performed to compare the safety and efficacy of adalimumab and methotrexate in children with severe psoriasis. Treatment groups consisted of a total of 114 patients who were randomly assigned to receive either 0.8 mg/kg of adalimumab, 0.4 mg/kg of adalimumab, or 0.1-0.4 mg/kg of methotrexate. Adalimumab was given subcutaneously every other week, whereas, methotrexate was taken orally once weekly. The study consisted of four periods; identified as the 16-week primary treatment, up to 36-week withdrawal, 16-week re-treatment, and 52-week long-term follow-up. Measurements based on the Psoriasis Area and Severity Index (PASI) assessed the percentage of skin affected and 75% improvement, PASI75, was a study endpoint. The Physician Global Assessment (PGA), which measures psoriasis activity, was used to identify clear or minimal areas. At week 16, PASI75 was achieved in 58% of the patients receiving 0.8mg/kg of adalimumab, in 44% of patients receiving 0.4 mg/kg of adalimumab, and in 32% of patients taking methotrexate. Results from the PGA showed 61% of patients receiving 0.8mg/kg of adalimumab, 41% of patients receiving 0.4 mg/kg adalimumab, and 41% of patients taking methotrexate had a clear or minimal PGA score. Initial treatments resulted in adverse events, such as infections for 45% of the patients receiving 0.8 mg/kg of adalimumab, in 56% of the patients receiving 0.4 mg/kg of adalimumab, and in 51% of those taking methotrexate. Compared to methotrexate, treatment with adalimumab in children and adolescents with severe plaque psoriasis provided significant improvements in PASI75. Although there was an increase in the number of patients with a clear or minimal PGA score in the adalimumab group compared to methotrexate, these results did not reach statistical significance. Overall, adalimumab was found to be more effective than methotrexate, with a rapid response and similar safety profile after 16 weeks.
This study is one of few investigations that characterize the long-term safety of treatment of severe psoriasis in children. Though a limitation of the study was a lack of methotrexate control data to compare to the investigated population, the safety and efficacy profile of adalimumab was successfully evaluated for comparison to methotrexate. In conclusion, treatment with 0.8 mg/kg of adalimumab for 16 weeks in children and adolescents with severe plaque psoriasis provided significant improvements in PASI75 and a non-significant increase in patients who achieved clear or minimal PGA compared with methotrexate. These findings provide new insight and an additional option for safe and effective therapy of severe plaque psoriasis in a young population.
Written By:Viola Lanier, Ph. D., M. Sc.
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Catalyst for genetic kidney disease in black people identified – Medical Xpress
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June 26, 2017 Credit: CC0 Public Domain
Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness - a variance that long has puzzled researchers. Now a study has found that the gene mutation's toxic effects require higher than normal levels of a protein called suPAR to trigger the onset and progression of the disease.
The results of the study, published in a research article in the journal Nature Medicine today, could lead soon to new treatments for chronic kidney disease that target these risk factors, according to Dr. Jochen Reiser, the senior author of the paper. Reiser is the chairperson of the Department of Internal Medicine and Ralph C. Brown MD Professor of Medicine at Rush University Medical Center, Chicago.
Chronic kidney disease - or CKD for short - is a progressive failure of function that prevents kidneys from fulfilling their role filtering waste from the blood stream. Nearly 17 percent of people in the U.S. have chronic kidney disease, and approximately 4 percent require dialysis and/or a kidney transplant due to kidney failure. Currently, there are no drugs that can treat CKD in an effective way.
Study analyzed samples from more than 1,000 people with genetic risk for CKD
For the study recounted in the Nature Medicine paper, Reiser worked with a team that included researchers at Emory University, Harvard University, Johns Hopkins University, the National Institute of Health, Ruprecht Karls University of Heidelberg, the Israel Institute of Technology and others. Together, they looked at two well-known genetic risk factors for CKD in black people, the mutated G1 or G2 variations in the gene known as apolipoprotein L1 (APOL1). To be at risk for developing CKD, an individual must have inherited two of these gene variants, one from each parent.
The study analyzed blood samples for suPAR levels, screened for APOL1 gene mutations and measured kidney function from two separate cohorts of black patients - 487 people from the Emory Cardiovascular Biobank, 15 percent of whom had a high-risk APOL1 genotype; and 607 from the multi-center African American Study of Kidney Disease and Hypertension, including 24 percent with the high-risk mutation.
Using these two large, unrelated cohorts, the researchers found that plasma suPAR levelsindependently predict renal function decline in individuals with two copies of APOL1 risk variants. APOL1-related risk is reduced by lower levels of plasma suPAR and strengthened by higher levels.
The team then went on and used purified proteins to study if suPAR and APOL1 bind to each other. They found that the mutated G1 and G2 variant did so particularly well on what's known as a receptor on the surface of kidney cells, in this case the suPAR activated receptor alphavbeta3 integrin. "This binding appears to be a key step in the disease onset" adds Dr. Kwi Hye Ko, a scientist at Rush and the study's co-first author.
This binding causes kidney cells to change their structure and function, permitting disease onset. Using cell models and genetically engineered mice, the authors then could reproduce kidney disease changes upon expression of APOL1 gene variants, but the disease required the presence suPAR.
Without elevated suPAR levels, genetic mutation much less likely to trigger disease
Everybody has suPAR, which is produced by bone marrow cells, in their blood, with normal levels around 2400 picogram per milliliter (pg/ml). As levels of suPAR rise, risk for kidney disease rises in turn.
Patients with levels above 3000 picogram per milliliter carry a much higher risk for kidney disease in the general population. Black people are particularly at risk, given the study's finding that suPAR activates its receptor on kidney cells that then attract the APOL1 risk proteins. Over time, these assaults can damage and eventually destroy the kidney.
On the other hand, without high levels of suPAR, the ability of the genetic mutation of APOL1 to exert its damaging effects is impaired, which helps identify patients in most need of suPAR lowering or future anti-suPAR therapy.
"Patients with APOL1 mutations who don't get kidney disease have more commonly low suPAR levels," said Dr. Salim Hayek, co-first author of the paper and a cardiologist at Emory University School of Medicine. "The suPAR level needs to be high to activate the mechanism in the kidney that enables APOL1 proteins" and set off the chain of events the genetic mutation can trigger.
suPAR 'is to the kidneys as cholesterol is to the heart'
Like some other pathological gene mutations, the APOL1 variations may have persisted in the population, in this case in Africa, because they could protect people from infection with the parasites known as trypanosome. explained Sanja Sever, PhD, co-correspondent author of the paper and associate professor of medicine at Harvard Medical School. In the United States, however, fighting parasitic trypanosomes isn't a significant concern, while lifestyle and environmental pressures such as obesity promote the rise in suPAR levels. This scenario sets up people for high risk of kidney disease.
Reiser has spent his career studying a scarring type of chronic kidney disease, focal segmental glomerulosclerosis. In past studies, he discovered that suPAR not only is a marker for kidney disease, but also a likely cause.
"What we are learning today is that suPAR in a general way is to kidneys what cholesterol is to the heart, a substance that can cause damage if levels rise too high, or a substance that can likely make many forms of kidney disease worse," Reiser says. "Based on these fundamental insights, suPAR level testing may become a routine test at many institutions around the world."
Like cholesterol, suPAR levels vary from person to person. Some environmental factors can contribute significantly to elevated suPAR levels. "Lifestyle is a big factor, bigger than we thought," Reiser says.
Smoking, weight gain and even frequent infections can add up and send suPAR to dangerous heights. Weight loss and smoking cessation can help bring levels down, but once elevated, suPAR may not recede to a healthy level again, said Dr. Melissa Tracy, co-author of the study and an associate professor of cardiology at Rush. People at genetic risk for kidney disease should aim to live a healthy life to keep suPAR levels low.
Explore further: Circulating blood factor linked with a leading cause of kidney failure
More information: A tripartite complex of suPAR, APOL1 risk variants and v3 integrin on podocytes mediates chronic kidney disease, Nature Medicine (2017). DOI: 10.1038/nm.4362
Patients with a disease that is a leading cause of kidney failure tend to have high levels of a particular factor circulating in their blood, according to a study appearing in an upcoming issue of the Journal of the American ...
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African Americans have a heightened risk of developing chronic and end-stage kidney disease. This association has been attributed to two common genetic variants - named G1 and G2in APOL1, a gene that codes for a human-specific ...
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Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness - a variance that long has puzzled researchers. ...
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Catalyst for genetic kidney disease in black people identified - Medical Xpress
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