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Daily Archives: June 3, 2017
DNA analyst: Muscle tissue delivered to downtown Greenville is ‘pretty unique case’ – WYFF Greenville
Posted: June 3, 2017 at 12:02 pm
GREENVILLE COUNTY, S.C.
A Greenville County DNA analyst says the case of a piece of muscle tissue being found in a container in downtown Greenville is a pretty unique case.
Greenville police said they were called to the CVS on Main Street Thursday about a shipping container that appeared to have a piece of muscle inside of it.
The coroner said a preliminary evaluation shows that the tissue is not a tongue, but appears to be skeletal muscle of some kind. DNA testing will be done to determine if it is human or animal.
Brian Browning, the DNA analyst for Greenville County Forensics, will do the testing on the tissue.
Its a mystery. Thats the reason theyre trying to investigate it. They dont know, number one, is it human? And number two, where did it come from and how did it get there, Browning said.
Browning said he will take samples of the tissue, extract the DNA and then determine how much human DNA, if any, is in the sample.
This is a pretty unique case, I gotta say. Getting tissue samples in general is pretty unique for us, but in this particular instance, getting that phone call was a new type of phone call, Browning said.
Police said the container appears to have originated in North Carolina and traveled through Georgia before arriving in Greenville.
They said detectives are working to track down the container's origins to see if an industrial or other accident may have occurred, or if there's any other explanation for the tissue.
Police said the container also held other products, but none of the products were meat- or dairy-related.
The tissue was being taken to the Greenville County Law Enforcement Center, and it will be evaluated by forensic investigators, Kent Dill, with the coroner's office, said.
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DNA analyst: Muscle tissue delivered to downtown Greenville is 'pretty unique case' - WYFF Greenville
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Fully sequenced deer genome made publicly available – Baylor College of Medicine News (press release)
Posted: at 12:01 pm
Researchers at Baylor College of Medicine have played a leading role in sequencing the whole genome of the common white-tailed deer, which has recently been made public by the National Center for Biotechnology Information.
The deer genome has the potential to provide insights into bone behavior, more specifically how deer are able to regenerate and repair bone after it is lost or damaged.
We are hoping that by understanding the deer genome in greater detail, we will be able to better consider how to approach and treat bone-related illnesses and disease, such as osteoporosis, said Dr. Brendan Lee, chair of the Department of Molecular and Human Genetics at Baylor. For example, antler growth each season is an example of the fastest and largest regenerating organ in nature.
By allowing the deer genome to be publiclyaccessible to researchers around the world, the NCBI is fostering collaboration among institutions when faced with solving complex cases or unidentified genetic conditions.
Sharing data is incredibly important in developing therapies for bone disease, added Lee, who also holds the Robert and Janice McNair Endowed Chair and Professor in Molecular and Human Genetics.
The sequencing of the deer genome was made possible through collaboration among the Center for Skeletal Medicine and Biology at Baylor, the Human Genome Sequencing Center at Baylor, the Rolanette and Berdon Lawrence Bone Disease Program of Texas, Berdon and Rolanette Lawrence, and the Caesar Kleberg Wild Life Research Institute. Prior to the publishing by the NCBI, the data was submitted to the National Institutes of Health.
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Fully sequenced deer genome made publicly available - Baylor College of Medicine News (press release)
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Team Maps Genome of Mojave Desert Tortoise – Arizona Public Media
Posted: at 12:01 pm
Researchers have finished the first full genome map of the threatened Mojave desert tortoise (Gopherus agassizii), also known as Agassizs desert tortoise.
Kenro Kusumi with Arizona State Universitys School of Life Sciences said the team hopes the data will aid conservation efforts, fill in blanks in the reptiles evolutionary history and perhaps offer clues to improving human health and longevity.
For diseases, were certainly interested in what makes them susceptible, the connection we study this in humans, too between their diet and their environment and their stresses, and their ability to fight off diseases," said Kusumi.
The research was published May 31 in PLOS ONE.
Mojave desert tortoises face threats from various quarters. Invasive grasses like red brome can stunt their early growth and may reduce their resistance to illnesses including upper respiratory tract disease (URTD), which afflicts the nose, nasal sinuses and trachea of some of the creatures. Humans threaten their survival by destroying habitat and building power lines, which provide new perches for predatory ravens.
Its a new habitat for the ravens. Its great for them, but its bad for baby tortoises, which they like to look at and then swoop down and eat, said Kusumi.
Based on comparisons with other existing reptile genomes, the study found changes in Mojave desert tortoise genes that regulate shell development, longevity and water conservation.
They also found that, among three desert tortoises (Mojave desert tortoise, Sonoran desert tortoise and Goodes Thornscrub tortoise), evolutionary forces seem to have differentiated protein sequences related to circadian rhythm the daily cycle of physiological and behavioral processes and the innate immune system.
The U.S. Fish and Wildlife Service listed the Mojave population that is located north and west of the Colorado River as threatened in 1990. Nevertheless, its numbers declined by about 50 percent from 2004 to 2013.
Understanding genetic variation and responses could help wildlife managers better grasp how disease and inbreeding affect the reptiles. Kusumi said it could also help scientist understand how the creatures adapt to their environs by isolating genes related to withstanding ultraviolet radiation and controlling urine volume.
We dont really know where the genetic treasure in the gold mine is. Where is the diversity that would allow the tortoise, as a species, to survive changes? said Kusumi.
A clearer picture of Mojave desert tortoises genetics and biodiversity could also improve management of reproduction and maintenance of habitat corridors, particularly under conditions of climate change. It would also help nail down the species geographical range, which overlaps with the Sonoran desert tortoise, aka Morafka's desert tortoise (Gopherus morafkai). The two desert tortoises sometimes mix boundaries and interbreed.
Were trying to answer, based on using the genome, where is the Mojave desert tortoise? Because we actually dont know exactly where that boundary is right now, said Kusumi.
Mojave desert tortoises live 40-50 years in the wild and more than 100 years in captivity. Dark green, with brown and yellow accents, they have rounded shells, stubby hind legs and flat front limbs built for digging. They occur in western Arizona, southern Nevada, Southern California and southwestern Utah. Kusumi said genetics could also offer clues as to how the species can live in such a diverse range of environments.
If you moved one from, say, Las Vegas to Southern California, it probably wouldnt do very well, because thats not the environment that its genome is making it suited for," he said. "So, within that species, wed love to know the genetic instructions that make a tortoise better suited for one place versus another.
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Repositive launches Personal Genome Project data collection – Business Weekly
Posted: at 12:01 pm
Repositive, the Cambridge company credited with creating the worlds largest portal for accessing human genomic research materials, has expanded the range of data available with the launch of a specialist collection for the Personal Genome Project.
The new PGP collection was formally unveiled this week at Repositives satellite symposium Finding and Accessing Human Genomic Data at EHSG in Copenhagen.
The initiative collates all the data collected for the Personal Genome Project in one place combining data currently held in the US, UK, and Austria.
The Personal Genome Project aims to sequence and analyse the genomes and medical records of 100,000 global volunteers. It contains large amounts of genomic data including whole genome sequencing, methylation analysis and RNA-Seq.
The new PGP specialist collection adds to Repositives series of community led data sets which include Autism, Microbiome, Personal Genomes, Population and Methylation collections.
CEO Fiona Nielsen (pictured) said: The Repositive Specialist Data Collections are already proving to be of significant benefit to many researchers. By collecting hard to find data in one place, we can ensure that researchers are able to quickly and easily find the data they need.
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Repositive launches Personal Genome Project data collection - Business Weekly
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Personal Genome Diagnostics Highlights its Patent-Pending Microsatellite Instability Testing Technology as FDA … – PR Newswire (press release)
Posted: at 12:01 pm
"This landmark FDA approval codifies the need to determine whether cancer patients potentially eligible for immuno-oncology therapy have microsatellite instability present in their tumors," said Doug Ward, CEO of PGDx. "It is particularly fitting that the approval involves MSI, a genomic condition whose relevance to cancer therapy was first uncovered by researchers at Johns Hopkins, with assistance from researchers at PGDx. We were thrilled to license rights to the patent-pending MSI measurement technology for immuno-oncology applications developed at Johns Hopkins, and are proud to be the first to offer it in both tissue and liquid biopsy formats. PGDx is also planning to submit a tissue-based MSI assay for FDA review later this year."
PGDx's MSI testing is incorporated in the company's tissue-based CancerSELECT 125 pan cancer genomic profiling assay and its non-invasive PlasmaSELECT 64 pan cancer assay that analyzes circulating tumor DNA in patient plasma. The company also recently received grant funding from the National Cancer Institute to advance liquid biopsy tests for determining a related biomarker known as tumor mutational burden.
PGDx was an early leader in identifying the importance of MSI, contributing to a study on MMR and immune checkpoint blockade presented at the 2015 ASCO Annual Meeting. In that study, researchers found that colorectal cancer patients who had tumors with MSI/MMR deficiency had a much greater therapeutic response to pembrolizumab. The analysis showed that cancer patients with MSI/MMR deficiency on average had more than 20 times the number of mutations in their tumors as similar patients who were not mismatch repair deficient. This finding is consistent with other studies showing that PD-1/PD-L1 checkpoint blockers are most effective against tumors containing many mutations. The study was published in the New England Journal of Medicine.
"We established PGDx to advance technology invented at Johns Hopkins based on our belief that greater understanding of tumor genomics would ultimately enable more effective and less toxic treatments for cancer," noted Victor E. Velculescu, MD, PhD, a co-founder of PGDx. Dr. Velculescu also is Professor of Oncology at the Johns Hopkins University School of Medicine. "This breakthrough approval from the FDA is an important milestone in the realization of that vision. I am proud that PGDx has played a significant role in this advance and that the company will help many more patients realize the benefits of immuno-oncology approaches for cancer treatment."
PGDx representatives will be attending the 2017 ASCO Annual Meeting and are available at Booth #2078 to discuss the company's MSI testing and its complete range of cancer genome analysis tools for researchers and clinicians. Research services include exome and targeted approaches for tissue specimens, targeted approaches for plasma samples and a variety of custom tissue and plasma-based options designed to address the specific research needs of cancer researchers and drug developers. PGDx's service offerings for researchers and testing labs are complemented by the clinical services it provides to patients and physicians through its CLIA-certified laboratory, including its CancerSELECT 125 pan cancer genomic profiling assay and the non-invasive PlasmaSELECT 64 pan cancer profiling assay, both of which include MSI testing.
About Personal Genome DiagnosticsPersonal Genome Diagnostics (PGDx) is empowering the fight against cancer by unlocking actionable information from the genome for oncology researchers, drug developers, clinicians and patients. The expert team at PGDx draws on a deep understanding of cancer biology, extensive experience in cancer genomics and clinical oncology, and the company's distinctive technologies that precisely identify and characterize unique genomic alterations in tumors. PGDx is working toward broad patient access to its genomic technologies and products, through a CLIA-certified facility providing comprehensive genomic services, as well as a portfolio of tissue-based and liquid biopsy genomic testing products for laboratories worldwide. Privately-held PGDx is headquartered in Baltimore, MD. For additional information, visit PersonalGenome.com.
To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/personal-genome-diagnostics-highlights-its-patent-pending-microsatellite-instability-testing-technology-as-fda-approves-keytruda-for-msi-tumors-300467763.html
SOURCE Personal Genome Diagnostics Inc.
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Personal Genome Diagnostics Highlights its Patent-Pending Microsatellite Instability Testing Technology as FDA ... - PR Newswire (press release)
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American Horror Story: The 100-Year Life – Seeking Alpha
Posted: at 12:01 pm
You think we have a retirement crisis now? Just wait. The worst impact will be to the 20 somethings and 30 somethings, and it has nothing to do with the funding of Social Security (at least not directly). I can't even comprehend my granddaughter's (age 5) generation.
Consider the fact that for more than 200 years life expectancy in developed countries (you can argue that's us) has increased 2 or 3 years every decade. Research complied by London School of Business professors Lynda Gratton (Management Practice) and Andrew Scott (Economics) show that most children born in the West (us) will live past their 100th birthday. This is not climate change, folks: there is no debate allowed here.
While human longevity has been happening all along, we build our life stages and plan our retirements around the same assumptions our parents and grandparents did. Consider Social Security, conceived in 1935 when folks were expected to work until they retired at 65 years old, and died at age 67. Forget about anything like funding shortfalls in 2038. It was and is not equipped to deal with a 40 year retirement. NOTE: LIFE EXPECTANCY FOR CHILDREN BORN IN 1930 WAS 58 FOR MEN AND 62 FOR WOMEN. Chew on that in the context of the creation of the Social Security System.
Professors Scott and Gratton wrote a dramatic book (best book I ever read not written by Kurt Vonnegut), THE 100 YEAR LIFE, published June 2, 2016. Everyone should read it.
They state that the gift of longevity carries with it the curse of having to cope with it financially and socially. They call for "deep seated social change" to occur at the economic, social, political, business and individual level. From the book: "We either can't afford to retire at the age our parents did or will have to work for so long that our mental and physical fitness as well as our enthusiasm for life could suffer. Individuals, companies and governments all have a role to play in ensuring we structure our lives differently so we can make the most of a longer life."
For those in their 40s-60s they advise, "Failure to innovate in response to a longer life will mean stresses and strains in your life as existing models are stretched uncomfortably over a 100 years."
Most of us over 50 have been and are ingrained in a three stage life: Education/training, career/work to accumulate, and retirement. This model will not and cannot hold. Professors Scott and Gratton predict we will have to move to a multi stage life, with perhaps several different career paths combined with pauses in between. They call it "individualized sequencing." Retirement will be in your 80s, if at all.
For those in their 20s, think in terms of delayed saving for retirement, delayed accumulation careers, life experience enjoyment earlier and periodically along the way. This is not a rose-colored glasses wish; it is happening now. The 20 and 30 year olds currently are saving little now and enjoying life more. Now. They are embracing the multi stage life, maybe without even knowing it. While we old folks may cringe at this and say "how frivolous," we are wrong. They are right.
Think of the business impacts. Human Resources needs to be refocused, careers have to be redefined, and the work-life balance made more flexible. Established corporations are built around the three stage life. Mark Zuckerberg and Elon Musk businesses, maybe not. After all, they're innovators.
Governments need to move toward "lifetime measures rather than age specific policies. It has to address "pensions, education, relationships, families, households and career breaks."
Think of the impact on financial firms, insurance companies (think what Long Term Care insurance will have to look like), healthcare systems (do you think your premiums will go down?), education institutions, recreation, retirement communities. The list is almost unending. It will have to be a massive total overhaul of the entire social infrastructure.
And what about personal finance in the days of the 100 Year Life?
My learned friend and colleague, Steve Barger says, "No one is preparing today's children or young adults for the probability that they will live to 100 or beyond. Living longer changes everything we do -early education, extended work, recreation, health care, financial responsibilities, retirement targets, re-training for new skills and learning new information possibly at age 75.
The primary source for life preparedness (our educational institutions K - 16+) are so blinded by political correctness that they have completely ignored one of life's critical survival skills: managing one's wealth.
There is not one college or university in this country that requires 'personal financial proficiency' in order to graduate. Where are our educational leaders? Nowhere to be found. How selfish and thoughtless. You should be ashamed."
What does it mean for me? I won't be around to see the upheaval.
What does it mean for my kids (38-42)? They're thinking and saving and have already foregone traditional careers for more creative, holistic ones.
What does it mean for my grandchildren (5-14-16)? They WILL live that multi stage life, starting with "do it now" (whatever "it" is).
What does it mean for you? Our ancestors were artisans. Think about learning a trade, no matter what age.
Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.
I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it. I have no business relationship with any company whose stock is mentioned in this article.
Additional disclosure: Quotes from THE HUNDRED YEAR LIFE by London School of Business Professors Andrew Scott and Lynda Gratton, Published June 2, 2016, and Steve Barger.
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Dermatitis | DermNet New Zealand
Posted: at 12:00 pm
Home Topics AZ Dermatitis
Author: DrAmanda Oakley, Dermatologist, Hamilton, New Zealand,1997.
Dermatitis refers to a group of inflammatory conditions. It affects the outer layer of the skin, the epidermis.
Dermatitis affects about one in every five people at some time in their lives. It results from a variety of different causes and has various patterns.
The terms dermatitis and eczema are often used interchangeably. In some cases the term eczematous dermatitis is used. Dermatitis can be acute or chronic or both.
An in-between state is known as subacute eczema.
Psychological stresses can provoke or aggravate dermatitis, presumably by suppressing normal immune mechanisms.
Treatment of dermatitis
An important aspect of treatment is to identify and tackle any contributing factors (see above).
Dermatitis is often a long-term problem. When you notice your skin getting dry, moisturise your skin again and carefully avoid the use of soap. If the itchy rash returns, use both the moisturiser and the steroid cream or ointment. If it fails to improve within two weeks, see your doctor for further advice.
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Topical Steroids : National Eczema Society
Posted: at 12:00 pm
For some people with eczema, the regular use of emollients is all that is needed to keep the condition under control. However, for many people there will be a time when a steroid preparation is required as part of their treatment in order to bring an eczema flare under control. Topical steroids are the most common treatment for eczema flares. This is when eczema becomes red, sore and very itchy. Topical steroids are used in short treatment bursts and should be used in conjunction with emollients. Emollients for washing, cleansing and moisturising are essential to a good skin care routine for treating and preventing dry and itchy skin.Emollients need to be used all the time. For more information on emollients click here. What are topical steroids?
Topical means something that is applied to the skin. Steroids are a group of natural hormones, produced in the body by a variety of different glands. They are also produced synthetically as medicines. The topical steroids used for treating eczema are totally different from steroids used in contraceptive pills or for bodybuilding.
Topical steroids are a valuable tool in the management of eczema. They reduce redness and soreness (inflammation) and can be very effective in controlling flare-ups, as they make the skin less itchy and sore, giving it a chance to heal.
Topical steroids are mostly prescribed to treat eczema flares. In this case, you will generally be instructed to apply topical steroid for short bursts of treatment, and then stop or step down use when the eczema flare settles. If you are prescribed a milder steroid you will generally be told to stop after a burst of treatment; but if you are prescribed a stronger steroid, you may be instructed to step down back to lower potency preparations as your eczema flare settles.
Sometimes people with more severe eczema whose eczema flares very frequently are prescribed topical steroids to apply on 2 consecutive days a week on the areas where their eczema usually flares. This is known as weekend therapy and can help to prevent the almost continuous flare cycle, meaning that in the long run less topical steroid would be needed to control the eczema than if each flare were treated as it occurs.
You will generally be advised to apply your topical steroid 12 times a day to areas of active eczema i.e. where it is flaring. (NICE Guidelines for children under 12 years recommend once a day.)
It is important to use the correct amount of topical steroid for your eczema, as instructed by your healthcare professional. Topical steroids should be applied with clean hands so that the skin just glistens. It can sometimes be difficult to judge how much steroid to use and there are guidelines on the amount required to cover body areas that are affected by eczema. These are based on the Finger Tip Unit (FTU), and explained in detail in our fact sheet which you can download as a pdf from the related documents to the right of this page.
There are no standard rules regarding whether to apply a steroid preparation after or before using an emollient. However, whichever order of care you choose it is important to leave as long a period as practical, of around 30 minutes, between the two treatments.
You may be given more than one topical steroid to treat your eczema; for example a milder steroid may be prescribed for the face or genital area and a stronger steroid for other parts of the body. Make sure that you are clear which preparation to use on which part of the body. If in doubt talk to your pharmacist /nurse or contact your doctor.
In the UK topical steroids come as ointments, creams, lotions, scalp applications and impregnated tape/plasters and in four different strengths:
Mild
Moderately potent
Potent
Very Potent.
In deciding which type you need, your doctor should take account of your age, the severity of the eczema, where it occurs and any other treatments you are using. Milder preparations are usually used for the face, genital areas or on babies.
The period of time a steroid may be used depends upon the severity of the eczema and the potency of the topical steroid. Your healthcare professional will advise you on this.
Some topical steroids have added ingredients and are sometimes prescribed where eczema is infected.
If you download our topical steroids factsheet look under related documents to the right of this page you will find tables listing the topical steroids currently available in the UK showing their potencies also which ones have added ingredients. Bear in mind that outside the UK treatments with the same or a very similar name may have different active ingredients and be of a different potency.
Topical steroids, used appropriately and under supervision, are a safe and effective treatment for eczema. The likelihood of side effects occurring is directly related to the potency of the preparation, where it is being used, and the condition of the skin on which it is used and the age of the person concerned. All these factors should be taken into consideration when a prescription is given to treat eczema.
Hydrocortisone 0.05%, 0.1%, 0.5% or 1% is extremely unlikely to cause adverse effects and can be used as prescribed on the face and in young children. Be careful not to confuse this with hydrocortisone butyrate, which is a potent topical steroid.
If used inappropriately or over long periods of time, topical steroids can thin the skin; blood vessels may become more prominent, and the skin can lose its elasticity, developing stretch marks. Other possible side effects include increased hair growth of very fine hair and perioral dermatitis (i.e. a spotty rash around the mouth).
Topical steroids have been in widespread use for over 50 years and although side effects can occur, as explained in our fact sheet available to download from the right of this page, this is usually because treatment has been used incorrectly. Under the supervision of a doctor, and used properly and sensibly in combination with good skincare as part of an overall management routine, topical steroids are a valuable treatment for eczema.
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Fend off Psoriasis and Eczema with Simple, Inexpensive …
Posted: at 12:00 pm
Eczema (atopic dermatitis), and the closely associated psoriasis, are two very common skin problems.
Both eczema and psoriasis are potentially allergic conditions that can be triggered by environmental factors and dozens of other external irritants like:
While psoriasis is most often linked with external allergic triggers, eczema is often caused by food allergies.
However, although theyre different diseases and have varying triggers, their treatments have many commonalities. .
Eczema is the itch that rashes, meaning, theres really no rash until you start scratching the itchy area. Hence, the first thing you need to do is to stop scratching!
Addressing the itch -- As anyone with eczema will attest, this is easier said than done. But fortunately, there IS a really simple, inexpensive way to relieve the itch: Simply put a saltwater compress over the itchy area.
Youll want to use a high quality natural salt, such as Himalayan salt. Simply make a solution with warm water, soak a compress, and apply the compress over the affected area. Youll be amazed to find that the itching will virtually disappear!
Another method that can be helpful for reducing or stopping the itch is EFT.
Proper skin hydration When working with any type of skin condition, you need to make sure your skin is optimally hydrated. Skin creams are rarely the answer here, but rather youll want to hydrate your skin from the inside out by consuming high quality, animal-based omega-3 fats in your diet.
Your best sources for omega-3s are animal-based fats like krill oil or fish oil. I also find it helpful to include a bit of gamma linoleic acid, typically in the form of primrose oil, as this works remarkably well for eczema. Products like krill for women are good for both sexes for this condition as they have both fatty acids.
Plant-based omega-3s like flax and hemp seed, although decent omega-3 sources in general, will not provide the clinical benefit you need to reduce inflammation and swelling in your skin.
Secondly, youll want to reduce your exposure to harsh soaps and drying out your skin with excessive bathing. Use a very mild soap when you cleanse your skin, especially in the winter to avoid stripping your skin of moisture.
Taking care of your gut = Taking care of your skin Many dont realize this, but the health and quality of your skin is strongly linked to the health of your gut. I recommend taking a high quality probiotic to ensure optimal digestive health. Fermented foods can be used as well, but are neither as common nor as easy to use.
Diet and skin quality Food allergies play an enormous role in eczema. In my experience, the most common offending agent is wheat, or more specifically, gluten. Avoiding wheat and other gluten-containing grains is therefore a wise first step.
If you were to visit my clinic outside of Chicago as a new patient, one of the first steps we would advise would be to go on a gluten-free diet for a number of weeks and carefully observe any health improvements. This is an enormously common problem and many of our patients are surprised to find how much improvement they actually achieve from this step.
Avoiding grains will also reduce the amount of sugar in your system, which will normalize your insulin levels and reduce any and all inflammatory conditions you may have, including inflammation in your skin.
Other common allergens include milk and eggs. I recommend you do an elimination trial with these foods as well. You should see some improvement in about a week, sometimes less, after eliminating them from your diet if either of them is causing you trouble.
Basking in the sun Vitamin D in the form of sun exposure is your best friend when dealing with either of these skin conditions, but its especially helpful for psoriasis.
I produced a one-hour lecture that explains the health benefits of this long under-appreciated vitamin, so if you havent seen it already, I strongly recommend you take the time to watch this free video now.
Ideally, youll want to get your vitamin D from appropriate sunshine exposure because UVB radiation on your skin will not only metabolize vitamin D, but will also help restore ideal skin function. High amounts of UVB exposure directly on affected skin but not so much to cause sunburn! will greatly improve the quality of your skin.
However, if you cant get sufficient amounts of sun during the winter months, a high quality safe tanning bed can suffice. A safe tanning bed will provide the optimized forms of UVA and UVB wavelengths, without dangerous magnetic skin balance.
You dont have to use expensive, dangerous medicines to treat eczema or psoriasis!
Steroid creams especially, are clearly something youll want to avoid, because although they work initially, you will tend to rapidly develop tolerance to them. These creams contain synthetic steroids, which are absorbed into your skin, and can wreak serious havoc with your adrenal system.
So please, avoid steroid creams and other potentially dangerous medications for these skin conditions and use these natural methods instead. Youll find they work almost all the time, especially if you diligently apply them.
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Does Diet Affect Eczema Treatment? – Care2.com
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There are many recognized triggers of eczema.
However, the role that diet plays is a murky area of research.
This article reviews the current evidence surrounding eczema treatment.
What is Eczema?
Eczema, also referred to as atopic dermatitis (AD), is a chronic and recurrent inflammatory skin condition that causes itchy, red, and swollen patches of skin.
Unlike psoriasis, eczema most often appears on the inside of the elbows and knees.
There are numerous types, butinfantile eczemais the most common developing in 1 in 5 infants (1).
However, know that eczema can affect anyone at any age. In fact, 334 million people worldwide were said to have eczema in 2013, and 10-30% of people in the U.S (2).
Unfortunately, rates have increased by 2 to 3-fold in Western countries over the past few decades (3).
Summary: Eczema is a common inflammatory skin condition, and rates are on the rise. The most common type is infantile eczema (occurs in children less than 5 years old).
What are the Causes of Eczema?
Several factors contribute to the likelihood of developing eczema.
Eczema risk factors include:
Summary: Many factors increase the risk of eczema including genetics, gender and immune abnormalities. Eczema is not an allergy but has many overlapping symptoms.
Conventional Eczema Treatment
Despite no known cure for eczema, various treatments are available to manage and prevent flare ups.
Dermatologists treat severe eczema with topical (on the skin) or oral medications and phototherapy. Milder cases require skin care and lifestyle modifications (8).
Commonly prescribed medications include anti-histamines, antibiotics, and corticosteroids (oral or topical). Unfortunately, these treatments also have undesirable side effects and lack long-term relief.
Those with eczema are also typically instructed to avoid common triggers including:
Summary: Eczema has no cure, but there are useful strategies for treating and preventing future flare-ups. Alongside medication, common triggers to avoid include dry climates and high stress levels.
Dietary Triggers to Eczema
Current research is unclear about the connection between eczema and specific food triggers.
Food Allergies and Eczema
Those with eczema are more likely to have food allergies, particularly in children under the age of 3 or 4.
Common food allergies in children with eczema include cows milk, eggs, peanuts, soy, wheat, cod/catfish and cashew.
Studies suggest the connection between childhood food allergy and eczema is 33 to 63%. Adult onset eczema is less likely linked with food allergy at a rate of 10%. However, this does not mean that food allergies cause eczema (10, 11).
Additionally, age reduces the likelihood that food allergy contributes to eczema, as most children outgrow their food allergies (12).
The exception is adults with a birch pollen allergy. One study found their eczema was triggered by foods that cross-react with birch pollen like green apples, carrots, hazelnuts, celery, and pears (13).
Therefore, if you have a birch pollen allergy and eczema, consider removing these foods from the diet.
Food Sensitivities and Eczema
IgE-mediated food allergy testing may have poor reliability in those with eczema.
Adults with eczema typically dont suffer from classic food allergies (i.e. IgE-mediated allergy), but rather experience delayed reactions after eating certain foods. This type of reaction is a delayed food hypersensitivity, also referred to as a food sensitivity.
Presently, there is no gold-standard test for diagnosing food sensitivities. Therefore, if you suspect food sensitivities trigger your eczema, consider keeping a food/symptom diary and working with a healthcare provider to identify problematic foods (14).
Pseudoallergens and Eczema
The connection between pseudo-allergens like food additives, histamine, salicylates and benzoates triggering eczema is controversial (15).
While the reason is still unclear, its theorized that these chemicals can cause inflammation in mast cells, a type of white blood cell. Those with eczema have higher levels of mast cells in the areas of skin with the rash (15).
One double-blind-placebo-controlled study on 50 adults found that 63% benefited from a 6-week low-pseudo-allergen diet. This diet avoided all foods containing preservatives, dyes and or antioxidants (16).
Celiac Disease and Eczema
Those with celiac disease (CD) are 3 times more likely to suffer from eczema (17).
Even relatives of those with CD are twice as likely to have eczema. This connection is based on the possible role of autoimmunity causing eczema (18).
Summary: Childhood eczema is more likely associated with food allergies compared to adult eczema. If you have birch pollen allergy or celiac disease, removing cross reactive foods and gluten helps.
Eczema Elimination Diet
Elimination diets are commonly recommended to help identify dietary triggers for a specific symptom.
A low FODMAP diet for food intolerance is the obvious example.
In this case it can be used as a home remedy of sorts for eczema treatment.
Following an elimination diet for 4 to 6 weeks may be beneficial for eczema sufferers. Remove all possible trigger foods and notice any changes in the skin (19).
There is no standardized elimination diet for this condition, but consider developing a plan based on your suspected trigger foods.
Below is a list of eczema trigger foods to help you get started.
Monitor eczema symptoms after strict avoidance of these suspected foods. While changes in symptoms may be coincidental, presence of food hypersensitivities could also explain the change.
Thereafter, carefully rechallenge the avoided foods back into the diet, ideally under the supervision of a dietitian or other health professional. When challenging foods, allow a few days between trials for the development of delayed symptoms (12).
This rechallenge plan for those on a low FODMAP diet may help you better visualize the concept.
Keep in mind that eczema has multiple causes and triggers. An elimination diet is not appropriate for everyone, so talk to your doctor or dietitian before starting one.
Summary: Some eczema sufferers may benefit from trialing a 4 to 6-week elimination diet based on their health history. Be sure to undergo this plan with the supervision of a healthcare professional.
Other Home Remedies for Eczema
Sometimes a change in diet does not provide much help.
Many search for other natural approaches instead:
Summary: There are many other natural therapies to help relieve eczema, however the evidence on most is limited. Consider these only after consulting with your doctor.
Treating Eczema Is Complex
Eczema is a complex inflammatory skin condition.
Its most common in children, but can develop at any age.
Conventional treatment options are available, yet dont offer long-term relief or a cure.
Unfortunately, there are no solid dietary recommendations either. Removing any known food allergies or sensitivities is a good place to start, which is best done through a structured elimination diet.
There are certain probiotic strains that are also worth exploring if you are struggling with symptoms.
Until we know more, its important you pay close attention to your body and notice if there are any specific dietary triggers for you.
This post originally appeared on Diet vs Disease as Does Diet Affect Eczema Treatment?
Disclaimer: The views expressed above are solely those of the author and may not reflect those of Care2, Inc., its employees or advertisers.
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