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Daily Archives: April 7, 2015
Bitcoin Foundation is effectively bankrupt, board member says
Posted: April 7, 2015 at 9:45 am
Further Reading One of the newly elected board members of the Bitcoin Foundationthe 2.5-year-old organization that was meant to bring order to the famously open source and freewheeling cryptocurrencyhas declared the group "effectively bankrupt."
While the Bitcoin Foundation obviously does not have control over Bitcoin itself, its the closest thing to a public face that the community has. Individual memberships start at $25, while corporate memberships start at $1,000 annually. The non-profits own tax filings from 2013 show that it ended that year with over $4.7 million in total assetsnearly five times as much as it had at the same time the previous year. It has yet to release financial details for 2014.
The organization was founded in 2012 by a number of Bitcoin luminaries who have since fallen, and the group itselfhas been marred by controversy in recent months. Of its original five founders, one isnowin prison (Charlie Shrem), another oversaw the collapse of the largest Bitcoin exchange (Mark Karpeles), and yet another has since left the United States for a Caribbean nation known for offshore banking (Roger Ver). Of the original board members, only Bitcoin lead developer Gavin Andresen has remained.
The Bitcoin Foundation did not immediately respond to Ars request for comment, nor did it address the issue on Twitter or its blog.
In a Saturday blog post, the new member, Olivier Janssens, claimed that the group has been hiding this financial distress from its membership. As he wrote:
The Bitcoin Foundation hates transparency. If they would have been transparent then everyone would know there is no money left. Something I think the members have a right to know, wouldnt you think? Members have a right to know that the current board failed to tell them the truth, and that their way of running the organization resulted in it going bankrupt. But instead of taking responsibility, they want to find the next executive director that will come up with another magic plan. Ironically, being transparent from the start might have prevented this whole thing to begin with.
Janssenspreviously said in May 2014 that he would resign his lifetime membership from the organization after board member Brock Pierce wasallegedlylinked to a sex abuse case. He ultimately decided not to leave it and wanted to reform thingsfrom withinJanssens recently stood for election to the groups board and succeeded on that effort.
"My big issue was that they did not tell the membership about the real financial status," Janssens told Ars via an encrypted chat on the Telegraph app."You cant be a member-run non-profit and still try to get money from your corporate or individual sponsors while hiding the fact that youre near-bankrupt. Thats the reason I came forward, I could not live with that. Thats up to the members to decide."
Janssens said he would prefer to heed whatever the groups existing members decide.
"If its up to me, Id make it a positive-only organization, no longer involved in any power position," he added."I would think its great to engage the members and make a map of every store in the USA, and have members go store to store to convince them of the benefits of Bitcoin, and in return they could get an affiliate percent or a referral reward. I also see the Foundation helping to organize mass changetip events to get a bitcoin (or bit) into the hands of every person in this world. For something like that, it can be very useful, and add a lot of value to Bitcoin itself. Its a non-threatening, positive thing to do."
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Bitcoin Foundation is effectively bankrupt, board member says
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Space From The International Space Station (ISS) – Video
Posted: at 9:44 am
Space From The International Space Station (ISS)
Space From The International Space Station (ISS) The International Space Station (ISS) is a space station, or a habitable artificial satellite, in low Earth orbit. It is a modular structure...
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Space From The International Space Station (ISS) - Video
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One-Year Space Station Mission Huge Step To Mars | Video – Video
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One-Year Space Station Mission Huge Step To Mars | Video
Slated to start at the end of March 2015, NASA astronaut Scott Kelly will spend a year aboard the International Space Station. Kelly, crewmate Mikhail Kornienko, and NASA explain how studying...
By: VideoFromSpace
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Space From The International Space Station (ISS) PT.2 – Video
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Space From The International Space Station (ISS) PT.2
Space From The International Space Station (ISS) PT.2 The International Space Station (ISS) is a space station, or a habitable artificial satellite, in low Earth orbit. It is a modular structure...
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Scott Kelly headed to space station – Video
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Scott Kelly headed to space station
Scott Kelly headed to space station.
By: ABC7 WJLA
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Scott Kelly headed to space station - Video
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INTERNATIONAL SPACE STATION ISS AND MOON FROM EARTH VISAKHAPATNAM INDIA – Video
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INTERNATIONAL SPACE STATION ISS AND MOON FROM EARTH VISAKHAPATNAM INDIA
INTERNATIONAL SPACE STATION ISS AND MOON FROM EARTH, VISAKHAPATNAM, INDIA.
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INTERNATIONAL SPACE STATION ISS AND MOON FROM EARTH VISAKHAPATNAM INDIA - Video
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Isolation Consolidation – Video
Posted: at 9:44 am
Isolation Consolidation
Bear Grilles shows that he doesn #39;t have what it takes to survive on a nearly-derelict space station. Did I mention that this is a spooky game?
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Isolation Consolidation - Video
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How to train your astronauts
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IMAGE:Astronauts Scott Kelly and Kjell Lindgren are shown during International Space Station EVA Maintenance 9 Training at the Neutral Buoyancy Lab at the Sonny Carter Training Facility. view more
Credit: NBL/Bill Brassard
Training an astronaut is no easy task. Astronauts go through years of rigorous technical, health and safety training to learn simple and complex tasks for a typical four to six month mission. They develop skills in systems, robotics, spacecraft operations, space engineering activities and even learn Russian. As NASA develops deep space exploration missions on its journey to Mars, the agency is investigating current training methods in order to adapt to the longer and longer missions.
"During the Shuttle Program, astronauts trained about 5 to 8 years for a 10 to 14 day mission, with a work-timeline scripted down to the minute." says Immanuel Barshi, a research psychologist from NASA's Ames Research Center in Moffett Field, California, in the center's Human Systems Integration division.
Decades of crew member research demonstrate that space can have adverse effects on people. Data suggests that the longer humans are in space, the greater the effects. On a trip to Mars, for instance, humans will be exposed to three years of microgravity and radiation; confined in an environment with three to five other people; separated from home; will experience altered day-night/light cycles; and will have three years to inevitably forget some of the training learned before leaving the planet.
Barshi's research, a study called Training Retention, examines to what extent these aspects of a Mars mission might affect a crew member's performance, as well as provide fresh insights into the way humans are trained for their jobs on Earth. Working with collaborators at NASA's Johnson Space Center in Houston, Barshi will study astronaut Scott Kelly's performance during his one-year mission aboard the International Space Station, in addition to that of other astronauts on six-month missions, and will compare results with astronauts on the ground over the same timeframe.
In conjunction with the Center for Research on Training at the University of Colorado in Boulder, Colorado, Barshi will compare the astronaut skill retention data from space and ground with that of undergraduate students. Much of what is known on how people learn and how well they retain information or skills is based upon university research. Such comparisons are critical to the application of ground assumptions to space operations, especially how the effects of long duration space travel affect crew members.
"Researchers know that skills retained for long periods are very specific, while generalizable skills decay much faster unless continuously practiced," says Barshi.
For example, a person can learn to enter the numbers 8675309 on a computer keypad extremely fast with excellent accuracy, and retain the skill for a long time. Ask them to do the same task, only this time using a different number sequence and the same person will be just as slow as another person who never practiced the original task. Meaning, it is the specific sequence of numbers that people remember, not the generalizable skill of entering any number.
Results from this study will not only inform choices about astronaut pre-launch, on-board and follow-on training, but they may apply to training requirements for other professional careers. Currently, high risk industries, such as oil drillers, nuclear power plant operators, medical doctors and aircraft pilots or air traffic controllers, set training requirements based upon industry consensus and not necessarily specific research.
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Sarah Brightman chases her dream to the International Space Station
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Brightman contributed to the design of her own mission patch for TMA 18/16M to commemorate her trip to the International Space Station in September. (credit: SarahBrightman.com)
In September, soprano and classical crossover performer Sarah Brightman, with cosmonaut Sergey Volkov and ESA astronaut Andreas Mogensen, will be launched from the Baikonur Cosmodrome in Kazakhstan to the International Space Station. She will be travelling as a spaceflight participant arranged by Space Adventures. Brightman will be only the second female spaceflight participant to travel to the ISS, after Anousheh Ansari in 2006.
Six men have also made the epic trip through Space Adventures. However, Brightmans worldwide fame will draw unprecedented attention to orbital personal spaceflight during her mission to and aboard the ISS. News networks will begin airing segments about her trip weeks in advance of launch. The day of launch it could be the top story on every news broadcast around the world. For Brightman, it will be the realization of a dream she has had for decades.
Brightman was born in August 1960, the first of six children. By the time of the Apollo 11 lunar landing in 1969, she had already been attending piano and dancing classes for five years. She had followed the news of the July 16 launch of the Saturn V carrying Neil Armstrong, Buzz Aldrin, and Mike Collins.
On July 20th, the Brightmans gathered their children around the television in their Berkhamsted, Hertfordshire, England home for the live broadcast. Millions of people were riveted to their TVs as the black and white video images were beamed live back to Earth. Sarah Brightman watched in wonder as Neil Armstrong stepped down the ladder of the lunar module. He cautiously placed his boot on the lunar surface and uttered those immortal words, Thats one small step for manone giant leap for mankind. At that moment, something clicked for Brightman, she recalled in an interview.
Being lucky enough to have watched the first man land on the Moon, Brightman said in a London press conference on March 10 hosted by Carol Vorderman, we thought we were going to be astronauts. It was all about space [back then]. For me to have got this far and to be able to have a taste of what I felt at the time, is an amazing thing.
Like many others who witnessed the first American astronauts to walk on the surface of the Moon, Brightman harbored the dream of one day going into space herself. She did not know how that might come about, but she always carried this dream with her. She continued her musical training and entered the Arts Education School in 1971. The die was cast, and Brightman embarked on a path that led her to stardom and worldwide fame. She focused on theater performance and later, her voice as a soprano having received her formal training at the Royal College of Music.
During the 1980s and the 1990s, Brightman continued to build a recording and performing career around the world. In 2001, she learned with interest of the flight of Dennis Tito to the ISS, arranged by Space Adventures. She became even more intrigued at the possibility when she read about Anousheh Ansarithe first female spaceflight participantwho achieved her own dream of going into space for an eight-day mission aboard the ISS.
On October 10, 2012, Brightman was in Moscow for a press conference where she would make a dramatic announcement. Also present were Alexey Krasnov, chief of Roscosmos Piloted Programs Department; Eric Anderson, Chairman of Space Adventures, Ltd.; and Neil Ford of UNESCO. The suspicions of the media that were present were confirmed before a word was even spoken. Being the consummate entertainer and performer, the conference opened with a music video showing film clips of Sarah Brightmans childhood interspaced with historic footage from American and Russian manned space missions, with a musical overlay of her singing Angel, from her upcoming album Dreamchaser.
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Can cancer vaccines prolong survival?
Posted: at 9:44 am
IMAGE:Cancer Biotherapy and Radiopharmaceuticals, published 10 times per online with open access options and in print, is under the editorial leadership of Co-Editors-in-Chief Donald J. Buchsbaum, PhD, Department of Radiation... view more
Credit: Mary Ann Liebert, Inc., publishers
ew Rochelle, NY, April 6, 2015--Therapeutic anti-cancer vaccines developed to treat metastatic disease such as advanced prostate cancer or melanoma rarely have a noticeable effect on the tumor but have been associated with a statistically significant increase in patient survival. Robert O. Dillman, MD, NeoStem, Inc., asserts that "overall survival" rather than "progression-free survival" should be the gold standard for evaluating the efficacy of cancer vaccines in clinical trials, in a provocative new article published in Cancer Biotherapy and Radiopharmaceuticals, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Cancer Biotherapy and Radiopharmaceuticals website until May 6, 2015.
In the article "Cancer Vaccines: Can They Improve Survival?" Dr. Dillman differentiates between the two key endpoints typically used to assess therapeutic cancer vaccines in clinical studies. As cancer vaccines are designed to stimulate an immune response to cancer cells and induce long-term memory recognition of a tumor, they may improve overall survival even if they do not appear to slow the progression of disease. Although measuring overall survival compared to progression-free survival would usually require longer clinical trials, overall survival may be the only relevant efficacy endpoint, the author concludes.
"This is a timely article considering the number of vaccine and antibody immunotherapy trials ongoing or planned," says Co-Editor-in-Chief Donald J. Buchsbaum, PhD, Department of Radiation Oncology, Division of Radiation Biology, University of Alabama at Birmingham. "The conclusion that overall survival is the best clinical endpoint for efficacy in therapeutic vaccine and antibody immunotherapy trials in patients with metastatic cancer is based on an analysis of four completed trials."
About the Journal
Cancer Biotherapy and Radiopharmaceuticals , published 10 times per online with open access options and in print, is under the editorial leadership of Co-Editors-in-Chief Donald J. Buchsbaum, PhD, Department of Radiation Oncology, Division of Radiation Biology, University of Alabama at Birmingham, and Robert K. Oldham, MD, CAMC-Teay's Valley Cancer Center. Cancer Biotherapy and Radiopharmaceuticals, celebrating 30 years in 2015, is the only journal with a specific focus on cancer biotherapy, including monoclonal antibodies, cytokine therapy, cancer gene therapy, cell-based therapies, and other forms of immunotherapy. The Journal includes extensive reporting on advancements in radioimmunotherapy and the use of radiopharmaceuticals and radiolabeled peptides for the development of new cancer treatments. Tables of content and a sample issue may be viewed on the Cancer Biotherapy and Radiopharmaceuticals website.
About the Publisher
Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many promising areas of science and biomedical research, including Journal of Interferon & Cytokine Research, Human Gene Therapy, and Stem Cells and Development. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN) (http://www.genengnews.com), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.
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Can cancer vaccines prolong survival?
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