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Daily Archives: March 2, 2015
Gene Therapy Section Formed Within the Alliance for …
Posted: March 2, 2015 at 6:42 pm
Edward Lanphier, President, Chief Executive Officer, Sangamo BioSciences; Jeffrey Walsh, Chief Operating Officer, bluebird bio; and Karen Kozarsky, Ph.D., Vice President, Research & Development, ReGenX Biosciences named as co-chairs
-- The Alliance for Regenerative Medicine and the American Society of Gene & Cell Therapy partner to support policies to advance novel gene therapies --
WASHINGTON, DC and SALT LAKE CITY, May 20, 2014 The Alliance for Regenerative Medicine (ARM) and the American Society of Gene & Cell Therapy (ASGCT) today announced their partnership. ARMs new Gene and GeneModified Cell Therapy Section (GTS) brings together the leading gene therapy companies and organizations in the U.S. and Europe to advocate for policies and programs to accelerate the development of new therapeutics to treat and cure a range of diseases for which no effective treatment options are available. ARMs focus on advocacy and clinical and commercial development will create a powerful alliance with the deep scientific and translational expertise resident in ASGCT.
The new ARM Gene Therapy Section is one of three technology sections that comprise the ARM membership. The other two sections focus on Cell Therapy and Tissue Engineering and Biomaterials. The Gene Therapy Section will dedicate its efforts to addressing regulatory, manufacturing, commercial and financial issues crucial to the success of the sector. In addition, the GTS will focus on building public awareness for this field of medicine and an appreciation for its potential to transform healthcare. The GTS will be led by Sarah Haecker, Ph.D., a member of ARMs senior staff. Sarah received her Ph.D. in Molecular Biology and Bioethics (with focus on gene transfer applications) and her postdoctoral scientific and business training in the Human Gene Therapy Program and the Center for Technology Transfer at the University of Pennsylvania. The three co-chairs of the group are Edward Lanphier, President, Chief Executive Officer, Sangamo BioSciences; Jeffrey Walsh, Chief Operating Officer, bluebird bio; and Karen Kozarsky, Ph.D., Vice President, Research & Development, ReGenX Biosciences.
As ARMs membership has grown, the organization has created specific technical sub-groups, such as the GTS, to focus on the unique development and commercialization needs of major sectors within advanced therapies said Lanphier. The addition of this new technology section is particularly exciting as the gene therapy field is making tremendous progress and holds great promise for transforming the lives of so many patients. It is our hope that gathering this group of technical, clinical and commercial experts in the field will help to accelerate product development and commercialization of these innovative technologies.
ASGCTs mission to bring together diverse stakeholders and advance the field of genetic and cellular therapies is closely aligned with ARMs goals, and we are looking forward to working with the organization, said Harry L. Malech, M.D., President-Elect of ASGCT. ARMs staff and members bring a wealth of knowledge involving regulatory and commercialization challenges in the field, and we feel this will nicely complement ASGCTs scientific and medical expertise.
ARM is the leading advocacy organization in the U.S. and Europe representing companies and organizations focused in the regenerative medicine and gene therapy field, and serves as an invaluable resource for all of its members. ASGCT, a nonprofit medical and scientific organization focused on genetic and cellular therapies, recently became a member of ARM and the two groups will work together to lead the advocacy and education efforts for the GTS of ARM.
Members of ARMs Gene Therapy Section: Abeona Therapeutics, AGTC, Alpha-1 Foundation, ALS Association, Association of Clinical Research Organizations (ACRO), American Society of Gene & Cell Therapy, Baxter/Chatham Therapeutics, Benitec Ltd., bluebird bio, Calimmune, Celgene Corporation, CIRM, Cornell University, Friends of Cancer Research, GenVec, Genzyme-Sanofi, Global Biotherapeutics, Juventas Therapeutics, MaxCyte, Memorial Sloan Kettering Cancer Center, National Multiple Sclerosis Society (NMSS), NeoStem, Oxford Biomedica, Parkinsons Action Network, Progenitor Cell Therapy (PCT), Pfizer, Prevent Cancer Foundation, ReGenX, Sangamo BioSciences, Shire, SironRX Therapeutics, Stop ALD, TissueGene, UniQure and Voyager Therapeutics
About The American Society of Gene & Cell Therapy: The American Society of Gene & Cell Therapy (ASGCT) is a professional nonprofit medical and scientific organization dedicated to the understanding, development and application of genetic and cellular therapies and the promotion of professional and public education in the field. For more information on ASGCT, visit its website at http://www.asgct.org.
About the Alliance for Regenerative Medicine: The Alliance for Regenerative Medicine (ARM) is a Washington, DC-based multi-stakeholder advocacy organization that promotes legislative, regulatory and reimbursement initiatives necessary to facilitate access to life-giving advances in regenerative medicine. ARM also works to increase public understanding of the field and its potential to transform human healthcare, providing business development and investor outreach services to support the growth of its member companies and research organizations. Prior to the formation of ARM in 2009, there was no advocacy organization operating in Washington, DC to specifically represent the interests of the companies, research institutions, investors and patient groups that comprise the entire regenerative medicine community. Today ARM has more than 150 members and is the leading global advocacy organization in this field. To learn more about ARM or to become a member, visit http://www.alliancerm.org.
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Gene Therapy Section Formed Within the Alliance for ...
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New Car Bonus Video #2 – Politically Incorrect/Seinfeld – Video
Posted: at 6:42 pm
New Car Bonus Video #2 - Politically Incorrect/Seinfeld
Another video of the too long conversations, this one about what is and isn #39;t PC, and also the lack of black people in Seinfeld (and we shot this a month bef...
By: PowerStationProd
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New Car Bonus Video #2 - Politically Incorrect/Seinfeld - Video
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Michael Cassidy To Star In Aseem Batra Pilot, Sam Huntington In How We Live
Posted: at 6:42 pm
Men At Work star Michael Cassidy is set as one of the two leads of another workplace comedy NBCs untitled pilot written by Aseem Batraand directed by Betsy Thomas. Thepolitically incorrect office comedy centers on best friends Dale (Cassidy) and Georgie whose relationship is upended when he starts dating the perfect woman. Batra is executive producing with Joe and Anthony Russo for Universal TV. Cassidy is with Gersh and Principal LA.
Being Human star Sam Huntington is set as the male leadin NBCs single-camera comedy pilot How WeLive,written bySteven Cragg andBrian Bradley and directed by Gail Mancuso. The projectcenters on Russell (Huntington), ablogger, and his wife Holly who move to the suburbs where he begins writing about marriage and the family lives of his suburban friends and neighbors, in the style of an anthropologist whos stumbled on an undiscovered tribe.Huntington is managed by Jared Schwartz at Generate and attorney is Harris Hartman.
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Michael Cassidy To Star In Aseem Batra Pilot, Sam Huntington In How We Live
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Local yoga teacher saw no sexual abuse from Bikram founder
Posted: at 6:42 pm
He is Bikram Choudhury, 69, the father of the famous Bikram yoga.
The reach of Bikram yoga is so far and wide that you can find a Bikram yoga-affiliated studio in almost every continent.
The man now finds himself in the midst of allegations of sexual assault and rape by women who had attended his classes.
Ms Diane Lee, 46, director of BYCH Hot Yoga here, had trained under him in 2004 at his international headquarters in Los Angeles.
She has been practising yoga since 2001 and Bikram yoga since 2003.
She says he never behaved inappropriately towards her and she did not see him misbehave with the other female students either.
But he had a habit of saying politically incorrect things.
"He said that all the time in my training. We just laughed about it.
People did say that enough is enough and it is true, it was wrong.
"But we all knew he is politically incorrect. He just says what he thinks.
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Local yoga teacher saw no sexual abuse from Bikram founder
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Chinas Internet censorship song – LoneWolf Sager (_) – Video
Posted: at 6:42 pm
Chinas Internet censorship song - LoneWolf Sager (_)
The Cyberspace Administration of China sang a song that promotes Internet censorship during a talent show hosted by the Beijing Internet Association. "Happy Valentines Day To All To All...
By: LoneWolf Sager
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Chinas Internet censorship song - LoneWolf Sager (_) - Video
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Travels with My Censor
Posted: at 6:42 pm
One reader said that the Chinese people adapt to censorship in clever ways. Credit Illusration by Javier Jan
My Chinese censor is Zhang Jiren, an editor at the Shanghai Translation Publishing House, and last September he accompanied me on a publicity tour. It was the first time Id gone on a book tour with my censor. When I rode the high-speed train from Shanghai to Beijing, Zhang sat beside me; at the hotel in Beijing, he stayed on the same floor. He sat in on my interviews with the Chinese media. He had even prepared the tour schedule on a spreadsheet, which was color-coded to represent five types of commitments, with days that lasted as long as thirteen hours. Other authors had warned me about such schedules, so before the tour I sent Zhang a request for more free time. His response was prompt: In my experience, the tours in China are always tough and exhausting. Hope you understand it.
And that was allno adjustment, no apology. In China, theres a tendency toward brutal honesty, and even the censored media may tell you things you dont want to hear. During my tour, one major Shanghai newspaper, Wenhui Daily, ran a six-thousand-word profile that began with the sentence Peter Hessler is now forty-five years old, and hes gotten a lot fatter, and he has wrinkles around the corners of his eyes. In Beijing, a television host finished his interview, shut off the camera, and said, To be honest, I liked your wifes book better than yours.
There are a couple of things that I should clarify. The first is that I weigh a hundred and fifty pounds. The second is that its not really fair to describe Zhang Jiren as a censor. Its true that he makes my books politically acceptable to the Chinese authorities, but censorship is only one of his duties. Zhang directs the nonfiction division at Shanghai Translation, where he also has to find translators, edit manuscripts, gauge political risks, and handle publicity. Hes thirty-seven years old but looks younger, a thin man with buzz-cut hair and owlish glasses. His background is in philosophy, and he wrote a masters thesis on Herbert Marcuse, the neo-Marxist thinker. Once, Zhang told me that he had studied Marcuse because his ideas are a powerful tool for Chinese to resist the long-term propaganda campaigns.
On the tour, Zhang was omnipresent, not because he wanted to monitor me but because he was responsible for virtually everything that happened. And yet his presence was quiet: usually, he was off to the side, listening and observing but saying little. He always wore sneakers, an old T-shirt, and calf-length trousers, and this casual outfit, during thirteen-hour days, sometimes made me feel like I was being given a tour of Purgatory by a neo-Marxist grad student. But I appreciated the guidance. Recently, there have been a number of articles in the foreign press about Chinese censorship, with the tone highly critical of American authors who accept changes to their manuscripts in order to publish in mainland China. The articles tend to take a narrowly Western perspective: they rarely examine how such books are read by Chinese, and editors like Zhang are portrayed crudely, as Communist Party hacks. This was one reason I went on the tourI figured that the best way to understand censorship is to spend a week with your censor.
Since Xi Jinping became President, in 2013, China has engaged in an increasingly repressive political crackdown. The authorities have also become more antagonistic toward the foreign press; its now harder for journalists to renew their visas, and many report being hassled by local authorities while on research trips. And yet the reading public has begun to discover nonfiction books about China by foreigners. More than any other editor, Zhang has tapped into this trendall but one of his six best-selling titles in the past few years have been foreign books about China. In Zhangs opinion, this reflects the new worldliness of readers, which he believes says more about the countrys long-term direction than the censorship or the propaganda does. The Party turns left this year, and maybe it turns right this year, Zhang wrote to me in 2014. In my opinion, the only certain thing is that Chinese people are much more individualized and open-minded.
In 1998, when I wrote River Town, my first book, it was inconceivable that a foreigners portrait of contemporary China would be published there, for reasons both political and commercial. There wasnt much of a market for books about China in the United States, either. I had just spent two years as a Peace Corps teacher at a college in Fuling, a small, remote city on the Yangtze River, and I finished the first draft without a contract. On the opening page, I wrote, There was no railroad in Fuling. It had always been a poor part of Sichuan Province and the roads were bad. To go anywhere you took the boat, but mostly you didnt go anywhere. The word poor appeared thirty-six times in the book; I used dirty more than two dozen times. I never thought seriously about such details until a publisher accepted the manuscript.
After that, I sent a draft to two friends from Fuling: Emily Yang, one of my former students, who was a native of the town, and Adam Meier, another Peace Corps volunteer. Their comments were almost completely contradictory. Emily wrote, I think no one would like Fuling city after reading your story. But I cant complain, as everything you write about is the fact. I wish the city would be more attractive with time. Meanwhile, Adam thought I had softened the portrayal. He was particularly concerned that I had omitted an incident that occurred near the end of our two years, when we went downtown with a video camera to record places that we wanted to remember. A crowd gathered and accused us of being journalists filming images of poverty to show Americans, which was a common charge at that time. We explained that we were teachers, but the crowd turned violent, kicking and hitting us until we ran away.
This was my most disturbing experience in Fuling, and I left it out of the first draft. One of the books main themes was the slow, sometimes painful way in which we had been accepted by locals, and I worried about undermining this message with a description of the mob in the final chapter. But, after discussing it with Adam, I decided that the scene was necessary. And this set the tone for my editing: I corrected details that were wrong, but I didnt touch anything that felt honest or raw. I left the word poor on page 1 and everywhere else that it appeared. I decided, effectively, that I would ignore a certain emotional side of the likely Chinese response.
I realized that I might not be welcome in Fuling after the book appeared. At the end of 2000, about a month before publication, I made a final trip to visit friends. I attended the wedding of one of my favorite former students, and then I gave a talk at a remote middle school where another former student was teaching. Shortly after I began my lecture, policemen arrived from Chongqing, the regional capital. They announced that the event was cancelled and escorted me off the stage. I returned to Beijing, and the following week almost everybody I had visited in Fuling was interrogated. The police detained the bride and groom to ask about our friendship, and another student telephoned me, sounding confused. Is it possible for the police to listen to what you say on the telephone? he asked. They knew all the things that you and I have been talking about recently.
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Travels with My Censor
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Serbia: Media and government
Posted: at 6:42 pm
U.S. expert on the Balkans Daniel Serwer recently published an analysis of the media scene in Serbia, regarding claims of censorship and stifling of media freedoms.
Serwer, senior research professor and senior fellow at the Center for Transatlantic Relations at the Johns Hopkins School of Advanced International Studies, wrote that he "asked a knowledgeable friend about media freedom in Serbia."
Noting that he was "prepared to publish other well-reasoned perspectives on this issue," Serwer posted the reply he received on is blog:
"Here is my theory on the Serbian media scene.
Media freedom activists (MFA) who claim there is censorship imposed directly by the Serbian government or even Prime Minister Vui himself and who consist of both journalists and nongovernmental organization representatives constitute a small fraction of people working in the media sector overall. Most journalists do not complain about censorship and perform their jobs normally.
Of course, being a minority does not mean being wrong. But in the case of the MFA, the problem is the argumentation they use in their attempts to prove that there is censorship. What they emphasize as their ultimate proof is that a vast majority of mainstream media never, or at most rarely, criticize Vui.
It is true that most media treat Vui in a positive way, but that does not necessarily have to be due to censorship by him or the government as a whole. The media do not operate in a vacuum; they are an integral part of broader society. As such, they reflect the general mood of the public. If Vui enjoys huge support from people, it is not surprising that most media might be reluctant to write or speak against him, even if they have grounds. They do not want to risk alienating their readers and followers, both actual and potential.
Even though Vui is today far more popular than Tadi ever was during his presidency (and certainly holds more power than Tadi did), when you compare the number and percentage of mainstream media that are currently pro-Vui with the number of those that were pro-Tadi when he was in power, youll see that, strangely, more media then favored Tadi than now favor Vui.
Another two factors that I believe contribute a great deal to sycophantic behavior of some media toward those in power (at any given time, not just at present) are opportunism and cowardice. An example of cowardice is when a journalist refrains from criticizing a politician in power not because someone influential warned them not to, but because of perceived fear of getting into trouble if they did. An example of opportunism is when a journalist (or editor) flatters powerful figures in hopes of earning privileges in return. Albeit different, both can be regarded as cases of self-censorship.
In terms of their attitude toward the ruling elite, Serbian mass media can be roughly classified into three basic categories.
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Serbia: Media and government
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Antivirus Maker Avast Is Latest Overseas Tech Firm Blocked In China
Posted: at 6:42 pm
Popular security software company Avast is the latest overseastechnology company to get caught in Chinas censorship net after users began reporting that its service and website were blocked inside the country.
Data from GreatFire.org shows that Avast.com has been unavailable in China since Sunday. Users of Avast which claims over 220 million global users of its antivirus and security products for Windows, Mac and Android posted screenshots on Weibo, Avasts forum and other sites showingissues.
Perhaps by coincidence, a recent Reuters report claimed that overseas antivirus firmsSymantec andKaspersky Lab had been removed froma list of approved anti-virus software vendorsfor state organizations.
We contacted Avast for comment but the company hadnot responded at the time of writing.
Update: We can confirm that Avast is being blocked in China and that we are actively investigating the situation, an Avast spokesperson told us.
Chinas so-called Great Firewall internet censorship system has treated overseas services and websites with increased hostility since the summer, when Google suffered an unusually log period of inaccessibility following the Tiananmen Square anniversary.
Gmail, among other Google sites, has yet to return to its usual levels, which has caused issues for business that rely on it for communications, while the blocking ofHSBCs online banking serviceandVerizons Edgecast networkhad repercussions.The blocking of Avast may also trigger similar frustrations from companies based in China that rely on its service (which includes a dedicated enterprise service) to maintain their security.
Image via Avast forum
It has been suggested that the crackdown on Avast could be related to a recent clamp down on VPN services, which letsusers access blocked websites from inside China. There is a VPN componentto Avasts software suite, but weve also heard unsubstantiated rumors that the company recentlyrefused to provide its source code to the Chinese government, as tech firms are now required to doaccording to a new draft law. If the latter is true, that may have led to its censoring.
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Antivirus Maker Avast Is Latest Overseas Tech Firm Blocked In China
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Donald Trump Disses Ron Paul, Calls Him Unelectable – Video
Posted: at 6:42 pm
Donald Trump Disses Ron Paul, Calls Him Unelectable
Donald Trump declares Ron Paul has zero chance and is unelectable at CPAC 2011.
By: wmerr
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Donald Trump Disses Ron Paul, Calls Him Unelectable - Video
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Political consensus urgent to protect human rights, Ban tells opening session of UN council
Posted: at 6:40 pm
2 March 2015 The United Nations has the mandates and tools it needs to prevent human rights violations, Secretary-General Ban Ki-moon told delegations gathered in Geneva today for the opening of the current session of the world bodys Human Rights Council, while he warned that the biggest challenge to using these tools is lack of political consensus among Member States.
I appeal to the Human Rights Council to unite behind early, practical steps to support national actors in promoting and protecting human rights. Early action on human rights helps to strengthen national sovereignty, rather than challenge or resist it, Mr. Ban said via video message at the opening of the three-day High-Level Segment of the 47-member bodys 28th session.
The world faces serious violations of human rights, from discrimination and inequality to oppression and violent extremism. Our shared challenge is to do far more to keep these and other abuses from occurring in the first place, added the Secretary-General, who was joined by the Councils President, Joachim Rucker, and UN High Commissioner for Human Rights, Zeid Raad Al Hussein.
The Council also heard statements from the President of The Former Yugoslav Republic of Macedonia, the Prime Minister of Fiji and dignitaries from 20 States who spoke about their concerns regarding the situation in a number of countries around the world and outlined some of the efforts their countries were undertaking in the promotion and protection of human rights.
Mr. Ban called the protection and realization of human rights intrinsic to the entire agenda of the United Nations and underscored the role of capacity-building, monitoring and reporting including through the work of the Human Rights Up Front Initiative. The conflict in Syria offers just one example where early United Nations efforts to address human rights violations might have averted a human and political catastrophe, he said, emphasizing that Member States must do their part to generate this much-needed shift in the way they work.
Also addressing the Council for the first time since taking his post last year, High Commissioner for Human Rights Zeid Raad Al Hussein said the world must be completely principled and cunning in its collective attempt to defang violent extremists.
For us, international humanitarian law and international human rights law cannot be trifled with or circumvented, but must be fully observed, Mr. Zeid stressed, saying how even though the UN Charter was established 70 years ago, with alarming regularity, human rights are disregarded, and violated, sometimes to a shocking degree.
States claim exceptional circumstances, he said. They pick and choose between rights. One Government will thoroughly support womens human rights and those of the LGBT communities, but will balk at any suggestion that those rights be extended to migrants of irregular status. Another State may observe scrupulously the right to education, but will brutally stamp out opposing political views. A third State comprehensively violates the political, civil, economic, social and cultural rights of its people, while vigorously defending the ideals of human rights before its peers.
Some of the evidence may be hidden. But the reality, in far too many countries, of massacres and sexual violence; crushing poverty; the exclusive bestowal of health-care and other vital resources to the wealthy and well-connected; the torture of powerless detainees; the denial of human dignity these things are known, he said, adding: And delegates, they are what truly make up a States reputation; together with the real steps if any taken to prevent abuses and address social inequalities.
The High-Commissioner said he is disturbed deeply by the disregard displayed by several States towards the Council's independent experts and also by the reprisals and smear campaigns that are all too frequently exercised against representatives of civil society.
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Political consensus urgent to protect human rights, Ban tells opening session of UN council
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