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Daily Archives: February 25, 2015
DNA analyses strengths and weaknesses of the Indian Cricket team ahead of WC 2015 – Video
Posted: February 25, 2015 at 12:43 am
DNA analyses strengths and weaknesses of the Indian Cricket team ahead of WC 2015
Zee News #39; cricket panel Navjot Sidhu, Shoaib Malik, Jadeja Gaurav Kapoor will on DNA analyse the strengths and weaknesses of the Indian Cricket team ahead ...
By: Zee News
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DNA analyses strengths and weaknesses of the Indian Cricket team ahead of WC 2015 - Video
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DNA test of Aam Aadmi Party’s Delhi Assembly election promises – Video
Posted: at 12:43 am
DNA test of Aam Aadmi Party #39;s Delhi Assembly election promises
Watch DNA test of Aam Aadmi Party #39;s Delhi Assembly election promises ahead of Arvind Kejriwal #39;s swearing-in ceremony. Also watch: Audio clip of #39;Anonymous ha...
By: Zee News
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DNA test of Aam Aadmi Party's Delhi Assembly election promises - Video
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rjm324 Plays Gender Bender DNA Twister Extreme #4 – Yael – Video
Posted: at 12:43 am
rjm324 Plays Gender Bender DNA Twister Extreme #4 - Yael
The epic conclusion to Yael #39;s storyline, now with 90% fewer censor bars. --------------- Don #39;t forget to like my Facebook page: http://www.facebook.com/pages/Rjm324/1486374121596535 And...
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rjm324 Plays Gender Bender DNA Twister Extreme #4 - Yael - Video
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The DNA Show Negatibo & Hearty Tha Bomb February 14, 2015 – Video
Posted: at 12:43 am
The DNA Show Negatibo Hearty Tha Bomb February 14, 2015
Isang masayang valentines episode tayo ngayon kasama sina Negatibo at Hearty Tha Bomb! Panoorin ang ka-kwenlahan nila kasa sina Aldrin at Nirro! LIKE : http://www.facebook.com/sirbisu A Video by...
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The DNA Show Negatibo & Hearty Tha Bomb February 14, 2015 - Video
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DNA with killerryan A0WN – Video
Posted: at 12:43 am
DNA with killerryan A0WN
Call of Duty: Advanced Warfare https://store.sonyentertainmentnetwork.com/#!/tid=CUSA00803_00.
By: Ryan Armentrout
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DNA with killerryan A0WN - Video
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2014 August Breaking News Mixing Human DNA with Animal DNA Last days final hour news proph – Video
Posted: at 12:43 am
2014 August Breaking News Mixing Human DNA with Animal DNA Last days final hour news proph
2014 August Breaking News Mixing Human DNA with Animal DNA - Last Days End Times News Prophecy Update - Genetic Engineering July 2014 Breaking News Mixing Hu.
By: NEW ILLUMINATI DOCUMENTARY 2015
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2014 August Breaking News Mixing Human DNA with Animal DNA Last days final hour news proph - Video
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MAURY: DNA Will Prove That I Didnt Make A White Baby 9/23/14 – Video
Posted: at 12:43 am
MAURY: DNA Will Prove That I Didnt Make A White Baby 9/23/14
i dont own the rights. i dont own the rights. Maury Show Full Episodes I #39;ll Prove A 13 Year Old Boy Fathered My Baby Part 1 yt:crop=16:9 Episode Detail: DNA Will Prove Your Husband Got Me...
By: Tonya Daniel
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MAURY: DNA Will Prove That I Didnt Make A White Baby 9/23/14 - Video
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Yeast behind velvety stout may have Silk Road origins
Posted: at 12:43 am
The study showed that yeast used to brew the perfect lager can also be pressed into service to produce excellent stout. Photograph: The Irish Times
There is nothing more Irish than the pint of plain but a DNA analysis of the yeast used to brew stout shows its origins are actually in India.
The same study also showed that yeast used to brew the perfect lager can also be pressed into service to produce excellent stout.
A research effort to build a comprehensive family tree of yeasts is under way, involving researchers from Trinity College Dublin and University College Dublin.
It even sampled naturally occurring yeasts in the wild.
There are two main groups of yeasts used to brew lager, and the researchers found that one of them shares DNA with the yeasts used to make stout.
But this DNA is also shared by a yeast strain used to brew Toddy, a speciality from southern India.
The research had uncovered new links between stout, ale and lager yeasts, said Prof Ursula Bond, associate professor in microbiology at Trinity.
The shared links joining stout, lager and Toddy yeasts also hinted at a colonial exchange of yeast strains between India and these islands some time in the past, she added.
There seems to be a link there. We are sequencing the genomes to see.
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Yeast behind velvety stout may have Silk Road origins
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Britain first to allow babies with 3 genetic parents
Posted: at 12:43 am
In this image made available by the Oregon Health and Science University, a faint white blotch in the tube at right is DNA that has been removed from a human egg, center. The red dot is from a laser used in the procedure. AP Photo/Oregon Health & Science University
Britain has became the first country in the world to allow babies to be created with the DNA of three parents. The House of Lords voted Tuesday to approve the use of a groundbreaking and controversial in-vitro fertilization technique known as three-parent IVF. That followed a similar vote in the House of Commons earlier this month.
The technique would likely only be used in about a dozen cases a year in the U.K. involving women with faulty mitochondria, the energy-producing structures outside a cell's nucleus. The genetic flaw can cause devastating inherited conditions in a woman's offspring including muscular dystrophy, mental retardation, and problems affecting the baby's heart and other vital organs.
To prevent that, scientists remove the nucleus DNA from the mother's egg and insert it into a donor egg from which the nucleus DNA has been removed. The resulting embryo would end up with the nucleus DNA from its parents but the mitochondrial DNA from the donor.
The British government published rules in December limiting use of the technique to cases of preventing genetic disorders. The U.K.'s Chief Medical Officer, Dr. Sally Davies, supported legalization "to give women who carry severe mitochondrial disease the opportunity to have children without passing on devastating genetic disorders."
Scientists say the DNA from the donor egg amounts to just a tiny fraction of the resulting embryo's genes, but that didn't ease the concerns of opponents, including the Church of England, who tried to stop a practice they considered "playing God."
"It would be hard to imagine a more controversial or passionate debate," CBS News correspondent Mark Phillips reported before the lower house of Parliament voted to approve it Feb. 3. "There was a lot of loaded language in this ... 'designer babies,' 'playing God,' 'three-parent babies.'"
Marcy Darnovsky, director of the campaign group the Center for Genetics and Society, called Tuesday's decision a "historic mistake" that will "introduce genetic changes that will be passed down to future generations," Reuters reported.
But supporters welcomed the new option for couples who want children despite the medical odds. Jeremy Farrar, director of the Wellcome Trust medical charity, said in a statement, "Families who know what it is like to care for a child with a devastating disease are best placed to decide whether mitochondrial donation is the right option for them."
Three-parent IVF is not approved in the United States, although the U.S. Food and Drug Administration is looking into it. The FDA held a meeting to discuss the technique last year and scientists warned it could take decades to determine its long-term safety.
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Britain first to allow babies with 3 genetic parents
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Study nearly triples locations in human genome that harbor microRNAs
Posted: at 12:43 am
According to the public databases, there are currently approximately 1,900 locations in the human genome that produce microRNAs (miRNAs), the small and powerful non-coding molecules that regulate numerous cellular processes by reducing the abundance of their targets. New research published in the Proceedings of the National Academy of Sciences (PNAS) this week adds another roughly 3,400 such locations to that list. Many of the miRNA molecules that are produced from these newly discovered locations are tissue-specific and also human-specific. The finding has big implications for research into how miRNAs drive disease.
"By analyzing human deep-sequencing data, we discovered many new locations in the human genome that produce miRNAs. Our findings effectively triple the number of miRNA-generating loci that are now known" says Isidore Rigoutsos, Ph.D., Director of the Computational Medicine Center at Thomas Jefferson University, who led the study. "This new collection will help researchers gain insights into the multiple roles that miRNAs play in various tissues and diseases."
For nearly three years, the team collected and sequenced RNA from dozens of healthy and diseased individuals. The samples came from pancreas, breast, platelets, blood, prostate, and brain. To their collection they also added publicly available data eventually reaching more than 1,300 analyzed samples representing 13 human tissue types. Their analyses uncovered 3,356 new locations in the human genome that generate over 3,700 previously undescribed miRNAs.
For a handful of the 13 tissues they studied, the team also had access to information describing miRNA association with Argonaute, an essential protein member of the regulatory complex that enables miRNA to interact with their targets. They found that 45 percent of the newly discovered miRNAs were in fact associated with Argonaute, a further indication that these molecules are involved in gene regulation. "We anticipate that many more of the newly discovered miRNAs will be found loaded on Argonaute as additional such data become available for the other tissues," says Eric Londin, Ph.D., an Assistant Professor and co-first author together with Phillipe Loher, M.S., a computational biologist and software engineer, both members of Jefferson's Computational Medicine Center.
One of the key design choices that the team made was to not limit their search to conserved genomic sequences, i.e. to only those sequences that are shared across multiple organisms. Instead the researchers scanned the genome much more broadly. "Advances in sequencing technology of the last several years made it easier to generate more data, from more tissues, and do so faster," says Dr. Rigoutsos who is also a researcher at the Sidney Kimmel Cancer Center at Jefferson. "Investigating the alluring possibility that miRNAs with important roles might exist only in humans was within reach. And this is what we set out to do."
Of the new molecules, 56.7 are specific to humans and most of them (94.4 percent) are found only in primates. Because of this organism-specificity these RNA molecules are involved in regulatory events that are absent from model organisms such as mouse and the fruit fly.
Tissue-specificity is another important characteristic of these new miRNAs. It means that these molecules are behind molecular events that are present in a single tissue, or in only a few tissues. Some of these molecules could potentially prove useful as novel tissue-specific disease biomarkers.
The tissue- and primate-specificity of the new molecules are expected to have important implications for the community's attempts to understand the causes of diseases. A first step in that direction requires the identification and validation of the targets for each of these 3,707 new miRNAs. To assist in these efforts, the team generated computational predictions of each miRNA's putative targets that are available from the Computational Medicine Center's website.
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The above story is based on materials provided by Thomas Jefferson University. Note: Materials may be edited for content and length.
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Study nearly triples locations in human genome that harbor microRNAs
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