Monthly Archives: January 2015

Manned commercial trips to ISS on track for 2017

Posted: January 26, 2015 at 9:45 pm

A Boeing CST-100 crew ferry craft blasts off atop an Atlas 5 rocket in this artist's concept. Boeing and SpaceX both expect to be ready for initial piloted test flights in 2017. NASA

Last Updated Jan 26, 2015 9:30 PM EST

NASA expects to spend some $5 billion underwriting development of commercial spacecraft built by Boeing and SpaceX to carry astronauts to and from the International Space Station, officials said Monday, ending sole reliance on the Russians for crew ferry flights and eventually lowering the average cost per seat to around $58 million.

Gwynne Shotwell, president and chief operating officer of Space Exploration Technologies, or SpaceX, said her company's upgraded Dragon V2 ferry craft should be ready for an initial unpiloted flight to the space station in late 2016 with the first crewed flight, likely carrying a SpaceX test pilot and a NASA astronaut, in early 2017.

John Elbon, vice president and general manager of Boeing Space Exploration, said his company's CST-100 spacecraft is expected to be ready for an uncrewed test flight in April 2017, followed by a crewed flight, with a Boeing pilot and a NASA astronaut, in the July 2017 timeframe.

Both companies must complete the crewed and uncrewed test flights before NASA certification, which will pave the way for the start of operational crew rotation and cargo delivery flights to the International Space Station later in 2017. Until then, NASA will continue to rely on Russia's Soyuz spacecraft to carry U.S. and partner crew members to the lab complex.

"Commercial crew is incredibly important to the space station, it's important to reduce the cost of transportation to low-Earth orbit so that NASA has within its budget the capability to develop means to explore beyond low-Earth orbit," Elbon said during a news conference at the Johnson Space Center in Houston. "And importantly, I think, it's beginning a whole new industry. ... We're making great progress on the program."

Said Shotwell: "Our crew Dragon leverages the cargo capability that we've been flying successfully to the International Space Station. However, we understand, and we've been told, that crew is clearly different. So there are a number of upgrades that we've been working for the past few years to assure that this crew version of Dragon is as reliable as it can possibly be. Ultimately, we plan for it to be the most reliable spaceship flying crew ever."

In the wake of the space shuttle's retirement, NASA started a competition to build a commercial crewed spacecraft, with the first in a series of contracts intended to encourage innovative designs for reliable, affordable transportation to and from low-Earth orbit.

Last September, NASA announced that Boeing had won a $4.2 billion Commercial Crew Transportation Capability (CCtCAP) contract to continue development of the company's CST-100 capsule while SpaceX would receive $2.6 billion to press ahead with work to perfect its futuristic Dragon crew craft.

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Manned commercial trips to ISS on track for 2017

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Integrins are essential in stem cell binding to defective cartilage for joint regeneration

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IMAGE:BioResearch Open Access is a bimonthly peer-reviewed open access journal led by Editor-in-Chief Robert Lanza, MD, Chief Scientific Officer, Advanced Cell Technology, Inc. and Editor Jane Taylor, PhD.... view more

Credit: Mary Ann Liebert, Inc., publishers

New Rochelle, NY, January 26, 2015--The promise for using mesenchymal stem cells (MSC) to repair cartilage damage caused by osteoarthritis depends on the MSC being able to attach efficiently to the defective cartilage. A novel laboratory model in which artificially created cartilage lesions and labeled MSC were used to test factors that might improve MSC binding and the effectiveness of future MSC-based therapies is described in BioResearch Open Access, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the BioResearch Open Access website.

In the article "1 Integrins Mediate Attachment of Mesenchymal Stem Cells to Cartilage Lesions," D. Zwolanek, PhD, and coauthors, University of Veterinary Medicine (Vienna, Austria), University of Cologne Medical Faculty (Germany), University Medical Center Rotterdam (The Netherlands) present the results of experiments using a combination of ex vivo and in vivo model systems of defective cartilage. They studied the effects of serum, plasma hyaluronic acid, and various cell adhesion-related proteins such as integrins on the attachment of MSC to the extracellular matrix of the cartilage.

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About the Journal

BioResearch Open Access is a bimonthly peer-reviewed open access journal led by Editor-in-Chief Robert Lanza, MD, Chief Scientific Officer, Advanced Cell Technology, Inc. and Editor Jane Taylor, PhD. The Journal provides a new rapid-publication forum for a broad range of scientific topics including molecular and cellular biology, tissue engineering and biomaterials, bioengineering, regenerative medicine, stem cells, gene therapy, systems biology, genetics, biochemistry, virology, microbiology, and neuroscience. All articles are published within 4 weeks of acceptance and are fully open access and posted on PubMed Central. All journal content is available on the BioResearch Open Access website.

About the Publisher

Mary Ann Liebert, Inc., publishers is a privately held, fully integrated media company known for establishing authoritative peer-reviewed journals in many areas of science and biomedical research, including DNA and Cell Biology, Tissue Engineering, Stem Cells and Development, Human Gene Therapy, HGT Methods, and HGT Clinical Development, and AIDS Research and Human Retroviruses. Its biotechnology trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first in its field and is today the industry's most widely read publication worldwide. A complete list of the firm's 80 journals, books, and newsmagazines is available on the Mary Ann Liebert, Inc., publishers website.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Integrins are essential in stem cell binding to defective cartilage for joint regeneration

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Inaugural Allen Distinguished Investigator Life Science Symposium

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Researchers to showcase groundbreaking work in: Cellular decision-making, human accelerated regions, medical research and lineage barcodes

The Allen Distinguished Investigator program supports high-risk, high-reward ideas in science. Award recipients typically receive nearly $1 million or more for three years of research. Without the ADI program, many of these innovative research projects would go unfunded.

Monday, February 9th, Allen Distinguished Investigator awardees will gather in La Jolla, California at the Scripps Seaside Forum for an all-day symposium. It's a unique opportunity to hear how these researchers are breaking new ground and making an impact on science today and in the future.

Presentations will feature various key award focus areas.

Cellular Decision-Making:

Thierry Emonet, Yale University; Thomas Shimizu, FOM Institute for Atomic and Molecular Physics; Steven Zucker, Yale University: Crowd Computing with Bacteria: Balancing Phenotypic Diversity and Coordinated Behavior.

Hana El-Samad, University of California, San Francisco: Untangling the Wires: An Integrated Framework for Probing Signal Encoding and Decoding in Cellular Circuits.

Jeff Gore, Massachusetts Institute of Technology: Microbial Studies of Cellular Decision-making: Game Theory and the Evolutionary Origins of Cooperation.

Suckjoon Jun, University of California, San Diego: Cell-Size Control and its Evolution at the Single-Cell Level.

Human Accelerated Regions:

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Inaugural Allen Distinguished Investigator Life Science Symposium

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AW: FR *SOLO* DNA on Solar – Video

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AW: FR *SOLO* DNA on Solar
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AW: *SOLO* SWITCH GUN EVERY KILL DNA BOMB – Video

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AW: *SOLO* SWITCH GUN EVERY KILL DNA BOMB
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AW: *SOLO* SWITCH GUN EVERY KILL DNA BOMB - Video

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Kino_Su: molecula de DNA – modelagem simplificada usando screw modifier e png – Video

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Kino_Su: molecula de DNA - modelagem simplificada usando screw modifier e png
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Kino_Su: molecula de DNA - modelagem simplificada usando screw modifier e png - Video

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DNA RNA – Video

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DNA RNA

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DNA RNA - Video

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AW: Ich bin gejoint…| DNA Bomb w/ASM1 on Comeback – Video

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AW: Ich bin gejoint...| DNA Bomb w/ASM1 on Comeback
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AW: *SOLO* DNA BOMB ( 55 GUNSTREAKS) EN CHANGEANT D’ARMES A CHAQUE KILL – Video

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AW: *SOLO* DNA BOMB ( 55 GUNSTREAKS) EN CHANGEANT D #39;ARMES A CHAQUE KILL
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AW: *SOLO* DNA BOMB ( 55 GUNSTREAKS) EN CHANGEANT D'ARMES A CHAQUE KILL - Video

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AW: Solo Double DNA HP | TOP 5 #2 – Video

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AW: Solo Double DNA HP | TOP 5 #2
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AW: Solo Double DNA HP | TOP 5 #2 - Video

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