Monthly Archives: November 2014

How We Proved There Was No Contamination in the Sasquatch Genome Project Samples – Video

Posted: November 15, 2014 at 4:42 am


How We Proved There Was No Contamination in the Sasquatch Genome Project Samples
This video shows how, as scientists, we can determine whether contamination is present in a DNA sample. It also addresses how peer reviewers failed to ask to see the raw data to determine whether...

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How We Proved There Was No Contamination in the Sasquatch Genome Project Samples - Video

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Semi-domesticated? House cats not far removed from wild, genome shows

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It may not surprise the average cat owner, but a team of researchers has discovered that the genome of domestic mousers differs only slightly from that of wildcats.

In other words, after 9,000-odd years of living alongside humans, the house cat remains only semi-domesticated, according to a report published this week in the Proceedings of the National Academy of Sciences.

After comparing the genome of an Abyssinian cat named Cinnamon with those of humans, tigers, cows, dogs and another cat breed known as the Birman, the scientists found that cats retain many of the hunting, sensory and digestive traits of their wild kin.

Researchers did find a signal for human influence on cat evolution, however, in fur color and pattern, as well as a set of genes that are thought to be associated with tameness.

We believe we have created the first preliminary evidence that depicts domestic cats as not that far removed from wildcat populations, said senior author Wes Warren, an associate professor of genomics at the Genome Institute at Washington University in St. Louis.

The discovery that as few as 13 genes may separate domestic cats from their wild ancestors was a genuinely important advance, according to John Bradshaw, an anthrozoologist at the University of Bristol School of Veterinary Sciences in Britain, who was not involved in the research.

This can only be the beginning of what will surely lead to a revolution in cat breeding, Bradshaw wrote.

By pinpointing genes responsible for cat behavior and temperament, humans could more easily guide more changes in the animal.

The potential is there to finally guide the cat through the remaining stage of domestication, not only producing cats that are better adapted to the demands of 21st century living, but at the same time enhancing their well being, Bradshaw wrote.

Unlike dogs, which some researchers say began their association with humans roughly 30,000 years ago, archaeological evidence suggests that cats first entered our living space when we began to grow crops, about 10,000 years ago.

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Semi-domesticated? House cats not far removed from wild, genome shows

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Eczema Cure – Video

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Eczema Cure
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Aveeno Eczema Therapy Moisturizing Cream – Video

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Dumaguing: Know More about Psoriasis

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FIRST and foremost, psoriasis is NOT a contagious disease. This strong statement hopefully, will remove, once and for all, the prevailing notion that psoriasis is a communicable and contagious disease, a misconception which has directly and indirectly put patients or if you may, sufferers of the disease, into pitiful situations like not being allowed to board a plane or eat in a high-end restaurant or even just being a seatmate in a classroom.

Second fact is that psoriasis is an inherited ailment. There is a trait handed down from parents to children, although not necessarily affecting all siblings. Genetic mutation has also been found to be a cause of the illness. The characteristic triad of psoriasis is thickening, redness and scaling. The extreme redness of the skin gives the impression to onlookers that there might be an infection, thus, their worry and eventual avoidance of close contact with the person.

The skin is now considered as the biggest organ in the human body, in terms of surface area. It has three layers; the epidermis being the outermost, serving as an effective protective barrier not only against microbes but also to harmful solar rays from the sun. The dermis is the middle, thickest and so-called vascular layer, whose blood vessels supply oxygen and nutrients to the overlying epidermis. The subcutaneous layer or tela subcutanea is made of fatty tissue, oleic acid being most abundant fat in it, colored bright orange-yellow because of the pigments carotene and xanthophyll. In normal, healthy individuals, it takes 28-30 days for the process of epidermidization - the replacement of the dead topmost layer of skin cells by new, young skin cells. In the case of persons with psoriasis, this process is much shorter that the skin cell turnover takes place within 3-5 days, thus resulting to an excessive accumulation of dead surface cells which later develop into scales and even bigger plaques. Dry and dead skins cells eventually slough off and shed leaving a fresh, reddish raw skin underneath the scales or plaques. Of course, itchiness or pruritus is a disturbing symptom which would make a person scratch the lesion and this invites infections especially with streptococcus and staphylococcus.

The author has been fortunate to watch the interview of Mr. Joseph de Guzman, President of Philippine Psoriasis Association and the doyenne of the VMV Skin Research Center, Dr. Vermen. M. Verallo-Rowell. The lady dermatologists, known both locally and internationally emphasized the two spikes of the occurrence of psoriasis in the lifetime of humans; the first being 18-25 years and the second spike when the person is 40-50 years old. There are sites of predilection; usually the scaling starts in the scalp, so much that dandruff or seborrheic dermatitis could be mistaken as psoriasis, although the amiable doctor said that the scalp scaling could be part and parcel of the disease. Skin folds particularly the knees and the elbows are also favored sites of psoriasis.

A whole body physical exam under natural light is imperative in the diagnosis of psoriasis, which could be mistaken as eczema, atopic dermatitis, or skin asthma. Contact dermatitis is the redness and inflammation of skin like earlobes wrist or fingers allergic to costume jewelries especially those containing nickel and alloy of metals. The treatment, although both Mr. de Guzman and Dr. Rowell were quite careful about declaring an absolute cure - depends on the extent of body surface involvement; less than 5 percent of the body would be mild, moderate if from 5-10 percent and severe if more than 15 percent of the body is involved in which, on top of the topical creams and lotions, the patient must take capsules or even receive injections to manage the signs and symptoms of psoriasis.

A very endearing and shall we say, nationalistic statement from Dr. Verallo-Rowell, who had extensive training abroad, extolled the virtues of our own coconut oil, especially if freshly-obtained. Zinc oxide applied properly serves as a skin barrier repair. While topical steroid creams significantly reduce the inflammatory skin reactions, Mr. de Guzman was quick to share experiences of his colleagues that more than two-weeks use could lead to thinning of the skin, making it susceptible to bacterial infection. Dr. Rowell encourages patients to get early morning sunshine, and swim in the sea preferably before 9 am and after 4 pm. Swimming pool has chlorine and hydrochloric acid in it so it may not be good for the psoriatic patient. Of course, for the real problematic cases, the cancer medicine Methotrexate or MTX is an effective last resort.

Dr. Verallo-Rowell clarified that a diagnosis of psoriasis is not as morbid as a death toll, sharing experiences with patients who, monitored regularly and obediently took their medicines, have had no flare-ups and in fact, brave and confident enough to walk down the ramp amidst glaring light of fashion shows or the scrutinizing close up on television interviews. More than that, she implored the public not to cast a disdainful look at persons with psoriasis but rather give them a compassionate, accepting and friendly smile.

Let's shake hands to that. Or better yet, why not a beso beso? Cheers!

Next Week: Let's hear it for deafness

Published in the Sun.Star Baguio newspaper on November 15, 2014.

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Dumaguing: Know More about Psoriasis

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Gene Analysis May Help Spot Ebola-Like Illnesses Before Symptoms Appear

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Latest Infectious Disease News

THURSDAY, Nov. 13, 2014 (HealthDay News) -- It may be possible to identify different types of hemorrhagic fevers -- including one related to Ebola -- before people develop symptoms, according to new research.

Scientists studied two hemorrhagic fevers, including a cousin of Ebola called Marburg and another called Lassa. Marburg causes occasional outbreaks in Africa that have high death rates, and Lassa is common is Western Africa, the researchers reported.

Using genetic material from white blood cells, researchers from the Boston University School of Medicine and the U.S. Army Medical Research Institute were able to recognize changes in the way the genes behaved in the early stages of infection. These changes occur before someone would even have symptoms, according to the researchers. They also occur before the infection could be passed to others, according to the study published recently in the journal BMC Genomics.

The findings could help lead to better ways to diagnose hemorrhagic fevers during the early stages, when treatments and containment efforts are more likely to be effective, the researchers suggested.

They noted that early indications of hemorrhagic fevers (fever, flu symptoms) are similar, which makes proper diagnosis difficult. More disease-specific symptoms and the ability to spread the virus from person to person don't begin until after the virus has accumulated in the blood.

"The ability to distinguish between different types of infection before the appearance of overt clinical symptoms has important implications for guiding triage and containment during epidemics," study corresponding author Nacho Caballero, a Ph.D. candidate at Boston University School of Medicine, said in a university news release.

"We hope that our study will help in the development of better diagnostics, especially during the early stages of disease, when treatments have a greater chance of being effective," he added.

However, Caballero noted that "this is not a finding that can be translated into a test tomorrow. This study supports the idea that early markers of infection are there, but significant work will still need to be done to extend these findings."

-- Robert Preidt

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Gene Analysis May Help Spot Ebola-Like Illnesses Before Symptoms Appear

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Politically Incorrect – Nov 13 2014 (made with Spreaker) – Video

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Politically Incorrect - Nov 13 2014 (made with Spreaker)
Source: http://www.spreaker.com/user/radiomarkowitz/politically-incorrect-nov-13-2014 The election is over and BHO is promising to ignore the Constitution, t...

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Politically Incorrect - Nov 13 2014 (made with Spreaker) - Video

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No point attracting young generation to F1 – Ecclestone

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Nov.14 (GMM) Bernie Ecclestone has ensured the world of Formula One on Friday will be discussing one thing -- his controversial views.

Amid collapsing teams and a so-called 'crisis' for his sport, the F1 supremo provided a diversion with a typically politically-incorrect interview for a publication called Campaign Asia-Pacific.

Now 84, the Briton once courted controversy by saying he admired Hitler, and he riled others by joking that women should be dressed white like other domestic appliances.

In Friday's interview, he said women "like to criticise", and likened collapsing backmarker teams to "ladies and credit cards".

I don't know what the so-called young generation of today really wants,

Bernie Ecclestone

And as Marussia and Caterham fight for survival, Ecclestone predicted nobody will miss them "at all" if they do fold.

"They've only got a name that people would know because of the problem they're in," said Ecclestone, comparing them the paralympic champion Oscar Pistorius who gained greater notoriety for the high-profile murder trial.

"Same with these two teams," said the F1 chief executive. "You need teams like Ferrari."

Arguably the most alarming comments, however, are about Ecclestone's attitude to social media, as he has been heavily criticised for not embracing the power of mediums like Facebook and Twitter.

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Swiss Gold Referendum, Baloney Mike Maloney & Baloney Boys Censorship – Video

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Swiss Gold Referendum, Baloney Mike Maloney Baloney Boys Censorship
SNB is..claiming..it will be willing to engage in unlimited intervention, said..JPMorgan http://www.bloomberg.com/news/2014-11-10/swiss-franc-cap-tested-as-gold-bugs-push-referendum.html...

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Common Reading Initiative – Censorship, Ownership and Digital Media – Video

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Common Reading Initiative - Censorship, Ownership and Digital Media
Dr. Scott Nokes leads a panel discussion on censorship in the digital media era.

By: TROY TrojanVision

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Common Reading Initiative - Censorship, Ownership and Digital Media - Video

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