Daily Archives: November 26, 2014

COD AW # DNA BOMB Fail – Video

Posted: November 26, 2014 at 1:47 pm


COD AW # DNA BOMB Fail
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COD AW # DNA BOMB Fail - Video

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Road to a DNA BOMB – Video

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Road to a DNA BOMB
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Road to a DNA BOMB - Video

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CoD AW – Quase DNA Bomb ( 21/0 ) – Video

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CoD AW - Quase DNA Bomb ( 21/0 )
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CoD AW - Quase DNA Bomb ( 21/0 ) - Video

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AW : "DNA BOMBE" | Ma prsentation pour la AllianceClanFR ! | [FR] – Video

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AW : "DNA BOMBE" | Ma prsentation pour la AllianceClanFR ! | [FR]
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AW : "DNA BOMBE" | Ma prsentation pour la AllianceClanFR ! | [FR] - Video

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DNA pioneer to sell Nobel Prize

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By Bryony Jones, CNN

updated 8:24 AM EST, Wed November 26, 2014

STORY HIGHLIGHTS

(CNN) -- DNA pioneer James Watson is to sell the Nobel Prize he won for his co-discovery of the double helix structure, the building block of life.

The coveted gold medal is expected to go under the hammer for up to $3.5 million in a sale at Christie's in New York on December 4.

It will be the first time a Nobel Prize has been sold by a living recipient.

Watson, now 85, was awarded the medal for work in the field of physiology or medicine alongside fellow scientists Francis Crick and Maurice Wilkins in 1962.

Nobel Peace Prize: They didn't win either

Nobel Peace Prize: They didn't win either

Nobel Peace Prize: They didn't win either

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DNA pioneer to sell Nobel Prize

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An enzyme that fixes broken DNA sometimes destroys it instead, Stanford researchers find

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PUBLIC RELEASE DATE:

26-Nov-2014

Contact: Rosanne Spector manishma@stanford.edu 650-725-5374 Stanford University Medical Center @sumedicine

Enzymes inside cells that normally repair damaged DNA sometimes wreck it instead, researchers at the Stanford University School of Medicine have found. The insight could lead to a better understanding of the causes of some types of cancer and neurodegenerative disease.

In a paper to be published online Nov. 27 in Molecular Cell, the researchers explain how the recently discovered mechanism of DNA damage occurs when genetic transcripts, composed of RNA, stick to the DNA instead of detaching from it.

Certain enzymes, called endonucleases, are attracted to DNA/RNA hybrids that form when gene transcription goes awry -- and they cut the DNA like scissors to damage it.

The researchers conducted the study with human cells in culture, using molecular biology techniques to turn off specific genes. This allowed them to induce cells to form the hybrids and to see what would happen when various enzymes were inhibited.

"What we found is when we get rid of these endonucleases, we don't see the damage," said Karlene Cimprich, PhD, professor of chemical and systems biology and the paper's senior author. "When those nucleases are present, they cut the DNA in the hybrid."

Both helpful and harmful

What's really interesting, said Cimprich, is these same enzymes are noted for fixing DNA damage. "They take part in the repair of DNA lesions from sunlight and certain chemicals, like those found in cigarette smoke," she said. The structures formed by the hybrid of RNA and DNA are similar to those formed in cells damaged by ultraviolet light.

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An enzyme that fixes broken DNA sometimes destroys it instead, Stanford researchers find

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James Watson's Nobel Prize for DNA work going on auction block

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NEW YORK, Nov. 25 (UPI) -- James Watson will become the first living Nobel laureate to sell his prize when the gold medal he was awarded for the discovery of DNA structure is auctioned in New York.

The prize could sell for as much as $3.5 million next week at Christie's in New York. Watson plans to use the proceeds to fund scientific research.

Watson, a native of Chicago, was a young researcher at the Cavendish Laboratory at Cambridge University in England when he met his collaborator, Francis Crick. He told CNN in a 2013 interview that Crick was the first person he met who shared his conviction of the importance of DNA.

Within a short time, they determined that DNA, the protein that forms genes, has a double helix structure.

"All we could say when we got it: It's so beautiful!" Watson said. "DNA was my only gold rush."

Watson, Crick and Maurice Wilkins of King's College in London, who had made important contributions in DNA research, were awarded the Nobel Prize in physiology and medicine in 1962.

Watson's notes for his acceptance speech and the manuscript of the lecture are also to be sold.

Crick died in 2004. A letter he wrote his son, Secret of Life, which explained the DNA structure days before the official announcement of the discovery, was sold last year for a record $6.06 million.

Watson, 86, is chancellor emeritus of the Cold Spring Harbor Laboratory in New York State. He said in a statement that the money from the sale would help him "in keeping the academic world an environment where great ideas and decency prevail."

"I look forward to making further philanthropic gifts to Cold Spring Harbor Laboratory, the University of Chicago, and Clare College Cambridge," he said.

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The Nightlife Genome Project – Video

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The Nightlife Genome Project
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Humanoid Opera – Paralyzed Genome (Live in The Cinema House Moscow) – Video

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Humanoid Opera - Paralyzed Genome (Live in The Cinema House Moscow)
Humanoid Opera - Paralyzed Genome (Live in The Cinema House Moscow) " " 2014.

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Blind Scottish Centipede Genome Unlocks Evolutionary Secrets

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November 26, 2014

Image Caption: This is Strigamia maritima, the centipede species genetically sequenced in the study. Credit: Dr. Carlo Brena

Eric Hopton for redOrbit.com Your Universe Online

An international group of scientists has completed the first ever genome sequence of a blind myriapod, Strigamia maritima. The species is one of a group of venomous centipedes that are unusual in the way in which they care for their eggs. The research also provides new insights into the biological evolution of Strigamia maritima and its unique absence of vision and circadian rhythm.

The work was partly carried out and the sequencing completed at Baylor College of Medicine in Houston, Texas, and the findings have been published online in the journal PLOS Biology.

This is the first myriapod and the last of the four classes of arthropods to have its genome sequenced, said Dr. Stephen Richards, assistant professor in the Human Genome Sequencing Center at Baylor. Arthropods are particularly interesting for scientific study because they diverged into more species than any other animal group as they adapted in many ways to conquer the planet. The genome of the myriapod in comparison with previously completed genomes of the other arthropod classes gives us an important view of the evolutionary changes of these exciting species.

Other scientists involved in the study were Dr. Ariel Chipman, of the Hebrew University of Jerusalem in Israel, Dr. David Ferrier, of The University of St. Andrews in the United Kingdom, and Dr. Michael Akam of the University of Cambridge in the UK.

Chipman, associate professor at the Hebrew University, said that The arthropods have been around for over 500 million years and the relationship between the different groups and early evolution of the species is not really well understood. We have good sampling of insects but this is the first time a centipede, one of the more simple arthropods simple in terms of body plan, no wings, simple repetitive segments, etc. has been sequenced. This is a more conservative genome, not necessarily ancient or primitive, but one that has retained ancient features more than other groups.

Fossil evidence shows that the myriapods, along with insects and spiders, were one of three independent arthropod invasions of the land from the sea. To adapt to life on land they had to learn to smell chemicals in the air, rather than taste them in the water. The research did indeed discover evidence of large gene expansions of the gustatory receptors which are believed to perform the same olfactory role that olfactory receptors play in insects, Richards said. This is a nice example of parallel evolution where different group of genes expanded, providing a different solution to the same problem, he added.

The findings indicate that this centipede group lost its eyes at least 200 million years ago. No vision-specific genes or genes related to the circadian (or internal) clock were found in the genome.

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Blind Scottish Centipede Genome Unlocks Evolutionary Secrets

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