Monthly Archives: May 2014

NASA Administrator Charles Bolden Discusses Space Station Science – Video

Posted: May 23, 2014 at 8:45 am


NASA Administrator Charles Bolden Discusses Space Station Science
NASA Administrator Bolden discusses the unique science accomplishments of the International Space Station (ISS) and plans for the future.

By: NASA

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SOUTH BY SOUTHEAST AT 1,423,884 FEET – Video

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SOUTH BY SOUTHEAST AT 1,423,884 FEET
What can you do with live streaming International Space Station hd video? Anything, once you put your mind to it. The USA to Brazil and beyond May 20 2014.

By: Douglas729

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SOUTH BY SOUTHEAST AT 1,423,884 FEET - Video

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Slowdive – "Souvlaki Space Station" (live at Village Underground, 19/5/2014) – Video

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Slowdive - "Souvlaki Space Station" (live at Village Underground, 19/5/2014)
Slowdive performing Souvlaki Space Station at their London comeback gig.

By: anorakhighst

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Slowdive - "Souvlaki Space Station" (live at Village Underground, 19/5/2014) - Video

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Space Station Robotic Handyman To Replace Canadarm2 Camera | Video – Video

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Space Station Robotic Handyman To Replace Canadarm2 Camera | Video
The Special Purpose Dexterous Manipulator (SPDM) aka Dextre, will replace a faulty camera near the elbow of its attached robotic arm. This will be the first ...

By: VideoFromSpace

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Destination Station: ISS Science Briefing – Video

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Destination Station: ISS Science Briefing
NASA #39;s Destination Station: ISS Science Forum is a public program dedicated to science aboard the International Space Station and discusses how venturing farther into the solar system to provide...

By: NASA

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Alexander Gerst: Bio and Training – Video

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Alexander Gerst: Bio and Training
In 2009, volcanologist Alexander Gerst from Germany became a member of the European Space Agency #39;s Astronaut Corps. Having undergone a rigorous international training programme, on 28 May...

By: European Space Agency, ESA

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Forum Highlights International Space Station Future Research

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Image Caption: An image of Crystal of Trypsin grown in microgravity during Expedition 4 on the International Space Station. Credit: NASA

Laura Niles, NASA

To highlight the direction for life and physical sciences aboard the International Space Station, a panel of experts gathered today for the Destination Station: International Space Station Science Forum. This forum, the first in a new series of public discussions dedicated to research aboard the station, emphasized current and future microgravity research that will prepare astronauts for long-duration missions farther into the solar system than ever before and provide lasting benefits to life on Earth.

Not only does the space station provide a one-of-a-kind orbiting laboratory for researching many science disciplines in microgravity, but it also serves as a technology development testbed for deep space exploration and is a destination to grow a robust commercial market in low-Earth orbit. While the use of the space station continues to grow, science studied aboard is underway at an unprecedented pace. In addition to continued scientific opportunity, there also are key areas in which to focus on the most crucial research needs in space.

In 2011, the National Research Council published a report on how best to use the space station. This report, entitled Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era, established priorities and provided recommendations for life and physical sciences research in microgravity for the 2010-2020 decade.

We took a broad look at what research needed to be done in the physical sciences and the life sciences to underpin the future of space exploration, said Elizabeth Cantwell, director for mission development in the engineering directorate at Lawrence Livermore National Laboratory in Livermore, California, and co-chair of the National Research Councils decadal study. We recommended that because animal studies underpin so much of our knowledge and understanding of human health terrestrially, that animal studies be supported more strongly in the space station science program and that microbial studies be beefed up in the form of long-term ability to study microbes in space on the space station.

Among other recommendations for the space station, the report endorsed a clearly defined and prioritized integrated life and physical sciences research portfolio and associated objectives. This report detailed seven major disciplines for focus by station research, including plant and microbial biology and animal and human biology.

Life science research already conducted aboard the space station includes studies of protein crystals, pharmaceutical treatments and model organisms like plants and fish. Model organisms have characteristics that allow them to easily be maintained, reproduced and studied in a laboratory and have a genetic makeup that is relatively well-documented and well-understood by scientists. Upcoming research in the area of omics, the study of the entire complement of biomolecules like proteins or genes, and in rodent research will further enable humans to carry out long-term space exploration and support a greater understanding of how gravity shapes fundamental biological processes.

In response to the report, we identified new facilities that we needed, like new rodent and plant habitats, and starting this year, those facilities are going to keep coming online one-by-one, and each will be used on every flight over and over on the space station for the next 10 years, said Julie Robinson, Ph.D., chief program scientist for the International Space Station.

Protein crystals have been studied in microgravity throughout the space stations assembly, and investigations using protein crystals continue today. High quality crystals grown on the space station are used to determine protein structure. This helps researchers understand better protein the three-dimensional structure of proteins and may lead to designing new therapeutics for diseases. In fact, a previous study of protein crystals on the space station led to the discovery of a water molecule in a protein-inhibitor complex that now is being used to develop a treatment for Duchenne muscular dystrophy.

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As defense budgets shrink, drive for international space cooperation grows

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Stars and Stripes

Published: May 22, 2014

COLORADO SPRINGS, Colo. Civilian space projects, including the International Space Station, have driven cooperation between the U.S. and its allies for more than 20 years.

With defense belt-tightening squeezing military space endeavors across Europe, North America and the Pacific, the people in uniform are hatching plans for similar cooperation in defense satellite work.

Some cooperative projects are already flying, including a military communications satellite used by American, Canadian and Australian forces. Air Force Lt. Gen. Ellen Pawlikowski told an audience at the Space Symposium in Colorado Springs on Wednesday that working with allies makes financial sense as the Pentagon plans to cuts billions from its space budget over the next decade.

"We needed to reach out and share the costs of access to space," said Pawlikowski who commands the Space and Missile Systems Center at Los Angeles Air Force Base, which develops the Air Force's new satellites and rockets.

Allies were reaching out to the U.S. at the Space Symposium, which drew a large international contingent among its 9,000 attendees.

"Let's be clear: It is very difficult for a single European nation to afford a full-spectrum capability," said Col. Dominique Arbiol, a French air force officer who oversees military space efforts there.

"My minister is very, very keen on international cooperation," said Cdmr. Volker Brasen, a German navy officer who serves as a top space officer in his country's defense ministry.

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Solestia – Genetic Engineering – Video

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Solestia - Genetic Engineering

By: BeyondTheBeyond

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Solestia - Genetic Engineering - Video

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Gene therapy extends survival in an animal model of spinal muscular atrophy

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PUBLIC RELEASE DATE:

22-May-2014

Contact: Kathryn Ruehle kruehle@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, May 22, 2014To make up for insufficient amounts of SMN protein, the cause of the inherited neuromuscular disease spinal muscular atrophy (SMA), researchers have successfully delivered a replacement SMN1 gene directly to the spinal cords of animal models of SMA. A new study demonstrating that enough copies of the SMN1 gene can be delivered to the spinal cord motor neurons to extend the survival of the treated animals is published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Human Gene Therapy website.

Marco Passini and coauthors from Genzyme (Framingham, MA), University of California San Francisco, Emory University School of Medicine (Atlanta, GA), and Georgetown University Medical Center (Washington, DC) used an adeno-associated viral vector as the delivery vehicle to transport copies of the SMN1 gene into motor neurons in the spinal cord via intrathecal delivery. They report on the effectiveness of restoring the levels of functional SMN protein in normal pig and non-human primate SMA models that would predict efficacy based on gene transfer with the same vector in an authentic mouse model of SMA in the article "Translational Fidelity of Intrathecal Delivery of Self-Complementary AAV9Survival Motor Neuron 1 for Spinal Muscular Atrophy."

"This is a very promising and thorough set of preclinical studies that supports rapid translation to the clinic," says James M. Wilson, MD, PhD, Editor-in-Chief of Human Gene Therapy, and Director of the Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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About the Journal

Human Gene Therapy, the official journal of the European Society of Gene and Cell Therapy, British Society for Gene and Cell Therapy, French Society of Cell and Gene Therapy, German Society of Gene Therapy, and five other gene therapy societies, is an authoritative peer-reviewed journal published monthly in print and online. Human Gene Therapy presents reports on the transfer and expression of genes in mammals, including humans. Related topics include improvements in vector development, delivery systems, and animal models, particularly in the areas of cancer, heart disease, viral disease, genetic disease, and neurological disease, as well as ethical, legal, and regulatory issues related to the gene transfer in humans. Its sister journals, Human Gene Therapy Methods, published bimonthly, focuses on the application of gene therapy to product testing and development, and Human Gene Therapy Clinical Development, published quarterly, features data relevant to the regulatory review and commercial development of cell and gene therapy products. Tables of content for all three publications and a free sample issue may be viewed on the Human Gene Therapy website.

About the Publisher

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