Monthly Archives: April 2014

Mayo Clinic launches 50-gene cancer panel test

Posted: April 28, 2014 at 10:43 pm

PUBLIC RELEASE DATE:

28-Apr-2014

Contact: Sam Smith newsbureau@mayo.edu 507-284-5005 Mayo Clinic

ROCHESTER, Minn. April 23, 2014 Mayo Clinic announces the launch of CANCP, a new gene panel cancer test to help tailor chemotherapy to the individual patient based on the unique genomic signature of the patient's tumor. CANCP, an abbreviation for Solid Tumor Targeted Cancer Gene Panel by Next-Generation Sequencing, scans specific regions in 50 genes known to affect tumor growth and response to chemotherapy. The test is now available to Mayo Clinic patients and to providers worldwide through Mayo Medical Laboratories.

"Every patient's cancer is different, and oncology is moving away from treating cancer based on its location in the body in favor of selecting the best medication for the individual patient based on molecular changes in the tumor," says Axel Grothey, M.D., a Mayo Clinic oncologist who orders CANCP on selected tumors. "This test helps providers identify such molecular changes without infusing irrelevant details from genes that we know will not affect our choice of medications."

The test is a hotspot panel, which means it scans specific regions of individual genes rather than the entire gene in search of tumor mutations that influence response to chemotherapy. It is designed for testing of solid tumors and focuses on clinically actionable alterations.

"We worked closely with oncologists, pathologists and molecular geneticists to develop and implement a next-generation sequencing assay that will have actionable results for providers," says Benjamin Kipp, Ph.D., a Mayo Clinic molecular geneticist and CANCP's lead designer. "This test focuses on results that oncologists can use to help find the right drug the first time."

Testing is conducted in the CLIA-certified Next-Generation Sequencing Lab of the Mayo Clinic Department of Laboratory Medicine and Pathology (DLMP). This is the second next-generation sequencing panel test offered by DLMP and Mayo Medical Laboratories. The other is a 17-gene screening test for hereditary colorectal cancers. Both were developed in collaboration with the Mayo Clinic Center for Individualized Medicine.

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Mayo Clinic launches 50-gene cancer panel test

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Film Director’s Criticism of Censorship Wins Resonance – Video

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Film Director #39;s Criticism of Censorship Wins Resonance
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Culture minister tackles censorship, smuggling

Posted: at 10:42 pm

BEIRUT: Censorship has no place in the Lebanese cultural milieu, Culture Minister Raymond Areiji told The Daily Star Monday. I am against any censorship on cultural events, and I mean movies, songs or anything else. In a country where politicians can say everything they want, insulting each other and harming national unity, it is not logical or healthy to have censorship on cultural products.

Controversial scenes in Western movies should no longer be edited out for Lebanese audiences, he added. Its been done for 30 years. But today when you cut a scene, you can find it immediately on YouTube. And when you cut a scene, you make people want to watch it even more. You emphasize it in a way the director didnt intend.

Reassessing censorship in the cultural sphere is just one of many projects Areiji hopes to tackle before a new president is elected and his mandate expires.

The Zghorta native revealed that his ministry was working on an ambitious new website that would feature more than 1,000 works by Lebanese grand masters.

These works are all held in the three official palaces to which the public have little access, he said. In collaboration with ALBA [Academie Libanaise des Beaux Arts] were creating a virtual museum where we can expose our collection.

Areiji is applying his 25-year career in law to his new post as minister. The cultural arena lacks a clear and modern legal framework, he said.

Im working on a new law for the protection of archaeological sites, he explained, and many other regulations that are lacking in this ministry.

As Lebanon has no dedicated Antiquities Ministry, questions of archaeology and preservation fall under Areijis mandate. Arbitrating between developers seeking to build glossy high-rises and conservationists hoping to protect ancient ruins has been one of the main issues his ministry faces, he said.

His predecessor, Gaby Layoun, sided with construction companies in a series of hotly disputed cases and drew particularly sharp criticism when he permitted the destruction of a Roman Hippodrome to make way for an exclusive new development.

We must find a balance between protecting our heritage and progress in the economy and real estate sectors, Areiji said.

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Can an Android App Defeat China's Internet Censors?

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By Lorenzo Franceschi-Bicchierai2014-04-28 20:22:39 +0200

China has long had one of the most pervasive online censorship systems in the world.

The country's infamous "Great Firewall" blocks access to numerous Western websites like Facebook, YouTube, Twitter and The New York Times. But China also has laws that force Chinese companies and social networks to apply censorship within their own services.

On Sina Weibo, China's Twitter-like service that boasts almost 300 million users, hundreds of posts get censored every day. The social network has a sophisticated system that automatically censors certain keywords ("June 4 massacre," referring to the Tiananmen Square protests, is blocked), and a team of in-house censors manually monitors other accounts and messages to catch whatever escapes the automated system.

Censorship on Sina Weibo is not only effective, it's lightning quick. Researchers last year found that some posts, or "Weibos," would be deleted as quickly as five minutes after being posted.

A secretive group of online activists called GreatFire has been monitoring Chinese online censorship for three years. GreatFire's three collaborators track blocked websites and collect censored posts on Weibo, which they then publish on FreeWeibo.com.

Now, the GreatFire activists are launching an app that they believe will make the Great Firewall of China and its mighty censorship powers obsolete, thanks to a relatively new approach called "collateral freedom."

The Android app, also called FreeWeibo, allows users to read posts that are deleted from Sina Weibo, giving Chinese netizens a chance to see what their government censors, and what their fellow countrymen are really talking about.

The activists believe that the way they designed the app makes it impossible to be blocked which they hope will show others an effective way to circumvent Chinese Internet restrictions, furthering their goal of ending online censorship in China.

"Since the founding of our organization, I don't think we've come as close to achieving that goal as we are about to with the release of [the FreeWeibo] Android app. Because it's really changing the rules of the game," says a GreatFire founder who goes by the pseudonym Charlie Smith, in an interview via encrypted phone with Mashable.

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Ron Paul Warned about an Armed BLM in 1997 – Video

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Ron Paul Warned about an Armed BLM in 1997
"Since groups demanding special favors from the federal government must abuse the rights and property of those who produce wealth and cherish liberty, real resentment is directed at the agents...

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Ron Paul: ‘Ukraine is not our business’ – Video

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Ron Paul: #39;Ukraine is not our business #39;
US politician Ron Paul, the so-called Godfather of the Tea Party movement, says "Ukraine is not our business".Sign up for Snowmail, your daily preview of what is on Channel 4 News, sent straight...

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Mark Driefus makes a post about libertarianism – Video

Posted: at 10:41 pm


Mark Driefus makes a post about libertarianism
ELMONT!

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Transhuman Visions – Free Lectures – Video

Posted: at 10:40 pm


Transhuman Visions - Free Lectures
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The reality will be stranger than Science Fiction: excerpt of talk at FutureDay 2014. Futurist Gerd – Video

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The reality will be stranger than Science Fiction: excerpt of talk at FutureDay 2014. Futurist Gerd
This is a brief except from my talk at Future Day 2014 in Istanbul, see http://gerd.fm/1mZmwGd for details, slides and full version, The entire talk is also ...

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The reality will be stranger than Science Fiction: excerpt of talk at FutureDay 2014. Futurist Gerd - Video

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Offline is the new luxury. Excerpt from my talk at FutureDay 2014. Futurist Speaker Gerd Leonhard – Video

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Offline is the new luxury. Excerpt from my talk at FutureDay 2014. Futurist Speaker Gerd Leonhard
Being in the moment matters, again:) This is a brief except from my talk at Future Day 2014 in Istanbul, see http://gerd.fm/1mZmwGd for details, slides and f...

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Offline is the new luxury. Excerpt from my talk at FutureDay 2014. Futurist Speaker Gerd Leonhard - Video

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