Daily Archives: April 24, 2014

Space station astronauts step outside to replace dead computer

Posted: April 24, 2014 at 5:46 pm

In a spacewalk lasting less than an hour, two members aboard the International Space Station successfully restoreda critical computer system.

A pair of NASA astronauts replaced a dead backup computer on the International Space Station during a short spacewalk Wednesday (April 23) to restore a critical computer system back to full strength.

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NASA astronauts Rick Mastracchio and Steve Swanson made quick work of their repair during the spacewalk, removing the faulty station computer and installing a spare less than an hour after floating outside the orbiting laboratory at 9:56 a.m. EDT (1356 GMT).

"It looks like a good day for you guys to take a walk in space," Mission Control radioed the astronauts as the spacewalk began. The spacewalk was slated to last only 2.5 hours. [See photos from today's spacewalk]

Mastracchio and Swanson replaced a computer known in NASA parlance as a Multiplexer-Demultiplexer, or MDM. The device is a backup computer for routing commands to systems supporting the space station's solar arrays, robotic arm rail car and other critical systems along the station's backbone-like main truss.

The 10-year-oldMDM computer failed on April 11during a standard test. The primary computer in the system is working fine, but NASA station flight controllers ordered today's repair spacewalk to restore redundancy in the system.

"Looks like we've got a new MDM," Mastracchio said as he finished the job.

A quick test showed the new computer was working fine.

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Fixing computers in space requires more than IT

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Astronauts Rick Mastracchio and Steven Swanson returned to the Quest airlock aboard the International Space Station at 11:32 a.m. EDT (GMT-4), ending a short but successful one-hour 36-minute spacewalk to replace a faulty external computer.

The start of the spacewalk, known as U.S. EVA-26, came just five hours after the departure of a Russian Progress supply ship that undocked from the Zvezda command module at 4:58 a.m. After moving about 300 miles ahead of the station, the uncrewed Progress will return and re-dock Friday to test an upgraded navigation and rendezvous system planned for future vehicles.

But the spacewalk was the focus for the station's NASA crew and flight controllers at the Johnson Space Center in Houston. The goal was to replace an external multiplexer-demultiplexer, or MDM, a 49-pound computer mounted in the central S0 segment of the station's solar power truss that failed April 11.

Less than an hour into a planned 2.5-hour spacewalk, Mastracchio and Swanson pulled a failed external computer from its rack in the central S0 truss segment of the International Space Station's solar power truss Wednesday and installed a replacement, making quick work of a critical repair.

Before unbolting the computer, Mastracchio reported there were no obvious signs of any damage in the area and examining the faulty "black box" after it was removed, he said everything looked good with no evidence of anything out of the ordinary. While additional troubleshooting will be needed to make sure, it would appear that an internal component failure of some sort was responsible for the original malfunction.

With the new computer in place, flight controllers sent commands to power it up and then began a series of diagnostic tests to verify its performance before uplinking the latest software. The faulty computer was carried back inside the station for troubleshooting and repairs.

"Your R & R was successful, we have a good MDM," Hansen called. "It's in diagnostic mode as expected."

"Oh, wonderful," one of the spacewalkers replied. "Fantastic," said the other.

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Satellite images provide a fresh look at Earth

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Robonaut 2 Getting Its 'Space Legs'

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Image Caption: International Space Station crewman, Dan Burbank, shakes hands with NASAs Robonaut 2. Credit: NASA

NASA

Getting your space legs in Earth orbit has taken on new meaning for NASAs pioneering Robonaut program.

Thanks to a successful launch of the SpaceX-3 flight of the Falcon 9/Dragon capsule on Friday, April 18, the lower limbs for Robonaut 2 (R2) are aboard the International Space Station (ISS). Safely tucked inside the Dragon resupply vehicle, R2s legs are to be attached by a station crew member to Robonauts torso already on the orbiting outpost.

R2s upper body arrived on the space station back in February 2011 during the last flight of the space shuttle Discovery. That event signaled the first human-like robot to arrive in space to become a permanent resident of the laboratory.

Jointly developed by NASAs Human Exploration and Operations and Space Technology mission directorates in cooperation with with General Motors, R2 showcases how a robotic assistant can work alongside humans, whether tasks are done in space or on Earth in a manufacturing facility.

NASA has explored with robots for more than a decade, from the stalwart rovers on Mars to R2 on the station, observes Michael Gazarik, the associate administrator for NASAs Space Technology Mission Directorate (STMD). Our investment in robotic technology development is helping us to bolster productivity by applying robotics technology and devices to fortify and enhance individual human capabilities, performance and safety in space.

Some assembly required

The R2 now consists of a head and a torso with two arms and two hands. With the addition of the newly developed climbing legs, the robot can augment its chief role: to help astronauts by taking over some of their duties on the space station.

But before R2 is up and running with its new limbs, theres some assembly required.

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Spacewalkers Make Quick Work of Computer Repair on Space Station

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Two astronauts quickly replaced a bad backup computer box and took on an extra task at the International Space Station on Wednesday during one of NASA's shortest spacewalks.

Within an hour, NASA astronaut Rick Mastracchio and Steve Swanson removed the old box, which failed to respond to commands on April 11, and installed a spare. Ground controllers reported that the new box, known as a multiplexer-demultiplexer or MDM, was working fine.

Mastracchio tucked the old box into an equipment bag and told Mission Control that he had "one MDM, slightly used."

"Nice and clean," Mission Control communicator Jeremy Hansen told the spacewalkers. "Good job."

Most spacewalks run for five or six hours, but this one lasted only an hour and 36 minutes arguably making it NASA's shortest glitch-free operation outside the space station.

An astronaut performs a repair job on the International Space Station during Wednesday's spacewalk.

Routine but critical task

The backup box is part of a redundant system that plays a part in controlling critical equipment on the station, including the solar arrays, a robotic rail car and the external cooling system. The primary computer box is working just fine, but NASA didn't want to go without a working backup any longer than necessary.

Replacing the box is considered one of the space station's "Big 12" routine maintenance tasks. Mastracchio and Swanson have been trained in advance for such jobs.

While Mastracchio switched the boxes, Swanson cut some dangling lanyards that had been blocking the way for the space station's Dextre robotic hand. In the future, Dextre might be able to perform maintenance tasks like the computer replacement without the need for a spacewalk.

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Astronauts replace computer outside space station

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Flight engineers Rick Mastracchio and Steve Swanson left the station's Quest airlock just after 10 a.m. EDT (1400 GMT) for what was expected to be a 2-1/2-hour spacewalk. They carried with them a spare computer to be installed in the central section of the station's exterior power truss.

"It looks like a great day to take a walk in space," Canadian astronaut Jeremy Hansen radioed to the crew from NASA's Mission Control in Houston.

NASA scheduled the abbreviated outing - most U.S. spacewalks last more than six hours - after the computer failed on April 11.

Replacing the computer is "pretty straightforward," astronaut and former space station crewmember Chris Cassidy said in an interview last week on NASA Television.

"We anticipate it to go quickly, but as with anything in space operations ... you never know what's going to be thrown at you," Cassidy said.

Except for emergency repairs, such as the computer replacement, NASA spacewalks remain suspended while engineers continue to assess the spacesuit failure last year that caused the helmet worn by Italian astronaut Luca Parmitano to fill with water, nearly drowning him.

The leak was later traced to a blocked filter. NASA flew new parts to the station for astronauts to make spacesuit repairs. Before two emergency spacewalks in December to fix the station's cooling system, astronauts also outfitted their helmets with absorbent pads and snorkels for breathing if the leak reoccurred.

Those spacewalks were completed with no problems. Mastracchio, who is making his ninth spacewalk, and Swanson, on his fifth, also included the snorkels and pads in their helmets for Wednesday's outing.

A new spacesuit was among the cargo aboard the Space Exploration Technologies' Dragon capsule that reached the station on Sunday.

NASA expects to resume routine spacewalks for maintenance and less-pressing repairs in July.

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How Sensitive Are Plants To Gravity?

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April 22, 2014

Image Caption: Space greenhouse. Credit: NASA

ESA

It is a race against time for ESAs Gravi-2 experiment following launch last Friday on the Dragon space ferry. Stowed in Dragons cargo are lentil seeds that will be nurtured into life on the International Space Station.

Gravi-2 continues the research of its predecessor into how sensitive plants are to gravity.

To find out, 768 lentil seeds will be subjected to different levels of simulated gravity. Spinning them in centrifuges at different speeds on the Space Station will recreate gravity, similar to how astronauts and fighter pilots are subjected to high-forces in human centrifuges.

The goal is to see at what gravity level the seedlings begin to show growth differences. Kept spinning for 30 hours at four different centrifuge speeds, the seedlings will be observed as they grow.

Anyone with plants at home knows that keeping a plant happy requires the right environment. The lentils need to survive a launch and grow in microgravity before they are chemically fixed to undergo detailed lab analysis on their return to researchers on the ground.

Dragons launch was expected a few weeks earlier and Gravi-2 researchers had to check that the lentils would survive the extra waiting time before launch. After testing, the lentil seeds were declared still fit to fly.

Once aboard, the plants will be grown in ESAs space greenhouse and time-lapse photography will show how the roots curve towards the downwards force.

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Deciphering Nature’s Alphabet – 3. Developing Genetic Tools – Video

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Deciphering Nature #39;s Alphabet - 3. Developing Genetic Tools
This film describes the conversion of these new DNA handling technologies into a viable business model that puts biology on the same plane as physics -- at least in terms of products it can...

By: GenomeTV

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Genetic Tricks Could Make Bionic Ears Hear Better

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A CT scan showing a cochlear implant in the left ear of a guinea pig. Image: UNSW Australia Biological Resources Imaging Laboratory, NationalImaging Facility of Australia, and UNSW TranslationalNeuroscience Facility

Scientists have devised a strategy they hope will one day make bionic ears even sharper. The idea is to make neurons inside the ear sprout new branches and become more sensitive to signals from a cochlear implant.

The cochlear implant is arguably the most successful bionic device ever invented. More than 200,000 people with severe hearing loss have received one, allowing them to understand speech and hear things like barking dogs and fire alarms. But theres plenty of room for improvement.

Pitch perception is not so good, and that impacts music appreciation and hearing in a complex environment like a noisy room, said Gary Housley, a physiologist and neuroscientist at the University of New South Wales in Australia, and the senior author of a new study out today in Science Translational Medicine.

To appreciate what Housleys team did, you have to picture whats going on inside the inner ear. The bony, spiral cochlea is where sound waves get translated into the electrical language of neurons. Its essentially a coiled tube. The implant is thin like a wire, and it has an array of electrodes along its length. Surgeons thread it into the tube of the cochlea.A microphone worn on the ear converts sound into electrical signals and transmits them to the implant, thereby stimulating the auditory nerve directly and bypassing whatever part of the persons own hearing apparatus has broken down.

A cross section of the spiral tube of the cochlea shows the auditory nerve reaching up through the center. Image: Grays Anatomy, via WikiCommons

But a lot of information gets lost in the communication between the implant and the nerve.

Housley thinks one important reason is that in people with severe hearing loss, auditory nerve fibers degenerate and shrink into the bony core of the cochlea, farther away from the implant.

To try to overcome this communication breakdown, Housleys team borrowed some tricks from genetic engineering. We refer to it as closing the neural gap, he said.

Work by other scientists had suggested that growth factorschemicals that encourage neurons to grow new branchescouldimprove the performance of implants in lab animals. These studies used viruses to deliver genes encoding the growth factors, but Housleys team tried another strategy they think could be more precise.

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GEN Publishing introduces 'Clinical OMICs' digital publication

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PUBLIC RELEASE DATE:

24-Apr-2014

Contact: Tamlyn Oliver toliver@clinicalomics.com 914-740-2199 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, April 24, 2014GEN Publishing recently introduced Clinical OMICs a semi-monthly digital publication focusing on the application of OMICs technologies in clinical settings. These advanced techniques, such as next-gen sequencing, are beginning to transform medical care just as they revolutionized basic life science research over the past decade-and-a-half.

"GEN's editors and reporters have written about the research use of pharmacogenomics, genomics, metabolomics, transcriptomics, etc. etc. for years," said John Sterling, editor-in-chief of Genetic Engineering & Biotechnology News (GEN). "The rapid advance of OMICs technologies has reached the point where we are convinced that the time is now for a new publication that shows how these diagnostic methodologies are dramatically impacting clinical practice."

Clinical OMICs is directed at clinical lab directors and managers, oncologists, infectious disease specialists, and cardiologists. Intended to serve as a resource for the development and standardization of best OMICs practices, Clinical OMICs provides critical information and insights on the trend toward personalized medicine.

The premier issue contains articles on translating OMICs into cancer biology and medicine, how payers are grappling with reimbursement issues, a profile of Lawrence Brody, who is overseeing NHGRI's new division of genomics and society, the move of next-gen sequencing systems into the clinic, and a case study of a genomics test for coronary artery disease. Late-breaking clinical OMICs news, OMICs-related clinical APPS, and new products are also featured.

###

About Clinical OMICs

Clinical OMICs is brought to you by GEN Publishing, the parent company of Genetic Engineering & Biotechnology News.

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Genetic code of the deadly tsetse fly unraveled

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3 hours ago Side view of a pregnant tsetse fly. Credit: Geoffrey M. Attardo

Mining the genome of the disease-transmitting tsetse fly, researchers have revealed the genetic adaptions that allow it to have such unique biology and transmit disease to both humans and animals.

The tsetse fly spreads the parasitic diseases human African trypanosomiasis, known as sleeping sickness, and Nagana that infect humans and animals respectively.

Throughout sub-Saharan Africa, 70 million people are currently at risk of deadly infection. Human African trypanosomiasis is on the World Health Organization's (WHO) list of neglected tropical diseases and since 2013 has become a target for eradication. Understanding the tsetse fly and interfering with its ability to transmit the disease is an essential arm of the campaign.

This disease-spreading fly has developed unique and unusual biological methods to source and infect its prey. Its advanced sensory system allows different tsetse fly species to track down potential hosts either through smell or by sight. This study lays out a list of parts responsible for the key processes and opens new doors to design prevention strategies to reduce the number of deaths and illness associated with human African trypanosomiasis and other diseases spread by the tsetse fly.

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"Tsetse flies carry a potentially deadly disease and impose an enormous economic burden on countries that can least afford it by forcing farmers to rear less productive but more trypanosome-resistant cattle." says Dr Matthew Berriman, co-senior author from the Wellcome Trust Sanger Institute. "Our study will accelerate research aimed at exploiting the unusual biology of the tsetse fly. The more we understand, the better able we are to identify weaknesses, and use them to control the tsetse fly in regions where human African trypanosomiasis is endemic."

The team, composed of 146 scientists from 78 research institutes across 18 countries, analysed the genome of the tsetse fly and its 12,000 genes that control protein activity. The project, which has taken 10 years to complete, will provide the tsetse research community with a free-to-access resource that will accelerate the development of improved tsetse-control strategies in this neglected area of research.

The tsetse fly is related to the fruit fly a favoured subject of biologists for more than 100 years but its genome is twice as large. Within the genome are genes responsible for its unusual biology. The reproductive biology of the tsetse fly is particularly unconventional: unlike most insects that lay eggs, it gives birth to live young that have developed to a large size by feeding on specialised glands in the mother.

Researchers found a set of visual and odour proteins that seem to drive the fly's key behavioural responses such as searching for hosts or for mates. They also uncovered the photoreceptor gene rh5, the missing link that explains the tsetse fly's attraction to blue/black colours. This behaviour has already been widely exploited for the development of traps to reduce the spread of disease.

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