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Daily Archives: April 3, 2014
NASA ISS Expedition Lead Scientist: Highlights: Week of March 24, 2014
Posted: April 3, 2014 at 8:46 pm
Aboard the International Space Station, Japan Aerospace Exploration Agency (JAXA) astronaut Koichi Wakata installed the canisters that arrived on the Soyuz spacecraft into the Protein Crystallization Research Facility for the JAXA Protein Crystal Growth (PCG) study. The main scientific objective of the investigation is to make fine quality protein crystals in space, and it will show how effective the space station is for investigations of this type. This experiment contributes to society by helping to design new drugs to fight diseases, and new catalysts for the environmental and energy industries.
NASA astronaut Steven Swanson set up blood and saliva collections for theSalivary Markersstudy. The investigationinvolves thecollection ofblood, saliva, urine and a health assessment on six subjects pre-, in- and post-flight to determine if spaceflight-induced immune systemdysregulationincreases infection susceptibility or poses a health risk to crews aboard the space station. The data collected during this study may lead to an understanding of how the immune system is affected by different factors from stress to the environment. The information could be used to help develop new treatments and preventative measures for immune dysfunctions.
The crew installed the 17 dosimeters -- a device for measuring doses of radiation -- that arrived on the Soyuz for the Area Passive Dosimeter for Life-Science Experiments in Space (Area PADLES) study. This investigation uses dosimeters to continuously monitor the radiation dose aboard the space station. Radiation exposure can have significant biological effects on living organisms, and on the biological investigations being done on the station and on the Japanese Experiment Module, known as Kibo.By installing dosimeters at 17 fixed locations inside the Kibo, continuous area radiation monitoring can be provided. The dosimetry technique is already used for dose management of radiation workers in high-energy accelelators. The high-speed microscope scanning image techniques are used in the diagnosis of cancer cells.
Wakata installed the passive dosimeters that arrived on the Soyuz for theDOSIS-3Dstudy. DOSIS-3D is short for Dose Distribution Inside the International Space Station-D. DOSIS-3D measures radiation field parameters such as absorbed dose and dose equivalent at different locations inside the space station, using active and passive radiation detector devices. The aim is to produce a three-dimensional dose distribution map of all segments of the station. This study further enlightens scientists of the use of devices for data collection and how to monitor real-time data. This could prove beneficial to radiation monitoring of commercial airline crews and military flight crews.
Operations were completed for the Superconducting Submillimeter-Wave Limb-Emission Sounder (SMILES) study. It was deactivated and will be disposed of on H-II Transfer Vehicle (HTV)-5. The main scientific objective of the SMILES mission is to study the recovery and stability of the stratospheric ozone, also known as the ozone layer. SMILES is the first aboard mechanically cooled superconducting mixer and high-resolution system for measuring atmospheric minor constituents related to stratospheric and mesospheric chemistry. It was launched on HTV-1 in 2009 and operated for over four years.
Other human research investigations continued for various crew members includingJournals,Reaction Self Test,Space Headachesand Space Linear Acceleration Mass Measurement Device (SLAMMD).
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NASA ISS Expedition Lead Scientist: Highlights: Week of March 24, 2014
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An Indie Look – Sol 0 – Video
Posted: at 8:46 pm
An Indie Look - Sol 0
The Transatlantic Gamer takes a look at an indie game, Sol 0! A mars colonization RTS type game thingamajig! You can find Sol 0 here: http://www.solzerogame....
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Seeds: A play for thinking audiences – Video
Posted: at 8:45 pm
Seeds: A play for thinking audiences
Actor Eric Peterson speaks about being drawn to the strength and determination of Percy Schmeiser. Having grown up in Saskatchewan Peterson has had a lot of ...
By: National Arts Centre Centre national des Arts
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Seeds: A play for thinking audiences - Video
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Dress and behavior of mass shooters as factors to predict and prevent future attacks
Posted: at 8:45 pm
PUBLIC RELEASE DATE:
3-Apr-2014
Contact: Kathryn Ruehle kruehle@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News
New Rochelle, NY, April 3, 2014In many recent incidents of premeditated mass shooting the perpetrators have been male and dressed in black, and may share other characteristics that could be used to identify potential shooters before they commit acts of mass violence. Risk factors related to the antihero, dark-knight persona adopted by these individuals are explored in an article in Violence and Gender, a new peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Violence and Gender website at http://www.liebertpub.com/vio.
In the article "Costuming, Misogyny, and Objectification as Risk Factors in Targeted Violence," Brian Van Brunt, EdD and W. Scott Lewis, The NCHERM Group, LLC (Malvern, PA), suggest reasons why persons who commit mass shootings are drawn to dark popular culture imagery, how these cultural factors may contribute to the violence, and what risk factors could be useful to law enforcement and behavioral investigation teams seeking to identify individuals who might be preparing for an attack.
"'Objectification' of victims and 'costuming' are specific offender behaviors that will give threat assessment teams throughout the world greater insights into the motivation of mass shooters and just how ceremonial their preparations are," says Mary Ellen O'Toole, PhD, Editor-in-Chief of Violence and Gender and Senior FBI Profiler/Criminal Investigative Analyst (ret.). "The value of this information in being able to identify these offenders beforehand based on their behavior so that we can prevent future acts of mass murder is very significant."
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About the Journal
Violence and Gender is the only peer-reviewed journal focusing on the understanding, prediction, and prevention of acts of violence. Through research papers, roundtable discussions, case studies, and other original content, the Journal critically examines biological, genetic, behavioral, psychological, racial, ethnic, and cultural factors as they relate to the gender of perpetrators of violence. Led by Editor-in-Chief Mary Ellen O'Toole, PhD, Forensic Behavioral Consultant and Senior FBI Profiler/Criminal Investigative Analyst (ret.), Violence and Gender explores the difficult issues that are vital to threat assessment and prevention of the epidemic of violence. Violence and Gender is published quarterly online with Open Access options and in print, and is the official journal of The Avielle Foundation.
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Dress and behavior of mass shooters as factors to predict and prevent future attacks
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Deadly Dinosaur Chase Reconstructed
Posted: at 8:45 pm
A set of prehistoric footprints, said to show meat-eating dinosaurs hunting vegetarian dinos, has just been recreated in a detailed 3-D model.
The frozen-in-time event, dated to at least 112 million years ago, happened at what is now the Paluxy River site in Dinosaur Valley State Park near the town of Glen Rose, Texas just southwest of Fort Worth.
The chase involved 20 to 30-foot-long predatory dinosaurs going after 30 to 50-foot-long dinosaur prey. While paleontologists arent yet certain of the species, Acrocanthosaurus (aka High-spined Lizard) is considered the likely hunter and Pleurocoelus (a hefty and impressively huge plant eater) the hunted.
Could These 10 Animals Be Resurrected?
It looks like one or more big predatory dinosaurs was stalking a herd of about 12 sauropods before the hunters went in for the kill.Some have suggested the tracks show one or more dinosaurs dying, since the footprints of young sauropods (the plant eaters) appear to trail off.
The chase scene has been known for some years. Unfortunately, after American paleontologist Roland Bird originally excavated the preserved footprints in 1940, researchers removed the tracks from their original location, divided them into blocks and transported them to various locations around the world.
Bird had documented the original site with photos and maps, but since that excavation, portions of the tracks have been lost. Peter Falkingham of the Royal Veterinary College, along with colleagues James Farlow and Karl Bates, decided to recreate the full set of dinosaur footprints.
When we first set out to map the Paluxy Rivertrack, creating an accurate 3-D model of the site required use of a large, heavy laser scanner that cost tens of thousands of pounds and was prone to failure especially in the extreme heat in Texas, Falkingham said in a press release.
Chicken from Hell Was a Fowl-Looking Dinosaur
They switched to a process called photogrammetry, which uses multiple digital photographs to generate a 3-D model. The process matches features between images and calculates relative camera positions. The researchers were even able to incorporate some of the original photos taken by Bird.
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Which couples who meet on social networking sites are most likely to marry?
Posted: at 8:45 pm
PUBLIC RELEASE DATE:
3-Apr-2014
Contact: Vicki Cohn vcohn@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News
New Rochelle, NY, April 3, 2014Nearly 7% of Americans married between 2005-2012 met on social networking sites. How those couples compare to couples who met through other types of online meetings or the "old-fashioned" way in terms of age, race, frequency of Internet use, and other factors is explored in an article in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Cyberpsychology, Behavior, and Social Networking website.
In "First Comes Social Networking, Then Comes Marriage? Characteristics of Americans Married 2005-2012 Who Met Through Social Networking Sites," Jeffrey Hall, PhD, University of Kansas, Lawrence, describes the characteristics that are more common among recently married individuals who met online via social networking sites (SNS).
"Facebook use grew dramatically during the 2005-2012 time period studied," says Brenda K. Wiederhold, PhD, MBA, BCB, BCN, Editor-in-Chief of Cyberpsychology, Behavior, and Social Networking, from the Interactive Media Institute, San Diego, CA. "It will be useful to continue to observe how these trends change as various groups of individuals become more frequent users of SNS," says Dr. Wiederhold.
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About the Journal
Cyberpsychology, Behavior, and Social Networking is a peer-reviewed journal published monthly online with Open Access options and in print that explores the psychological and social issues surrounding the Internet and interactive technologies, plus cybertherapy and rehabilitation. Complete tables of content and a sample issue may be viewed on the Cyberpsychology, Behavior, and Social Networking website.
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Which couples who meet on social networking sites are most likely to marry?
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GMO foods have caused nary a sniffle, sneeze or bellyache
Posted: at 8:45 pm
From buying organic to gluten-free, consumers seem to be more interested than ever in the ways their food is produced.
This spring, legislators in more than 20 states will consider proposals to mandate special labeling of genetically modified foods, to give shoppers one more bit of information.
Critics say genetically modified foods might be unsafe, but even if they are not, consumers have a right to know what is in what they eat.
So, why not tell people if the ingredients in their cupcakes and cereal have been engineered, and let them decide what to buy?
This may sound reasonable and seem to reflect how our choice-driven marketplace works. But, it reflects a deep misunderstanding about what genetic engineering actually is and how it compares to the changes we have been making to crop plants for thousands of years.
For starters, nearly every food on grocery store shelves has been modified by human hands at the genetic level. In the agriculture world, its called breeding. And, as many of us learned in high school biology class, breeding alters a plants genes so it expresses new traits.
This may be as simple as a new color or flavor, or even resistance to pests and plant diseases.
And, whether we use genetic engineering or more conventional techniques, breeding can mean just tweaking the genes already inside a plant or introducing entirely new ones.
The primary thing that makes genetic engineering unique is the power and precision it gives us to make those changes and then test for safety afterward. It has also given us food that is both safer for our families and better for the environment.
Plants with a built-in resistance to chewing insects, for example, have allowed farmers to use millions of gallons less pesticide every year.
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University of Nebraska Medical Center Selects Cartagenia Bench Platform for NGS and Array …
Posted: at 8:45 pm
Enabled Reduced Analysis Time Per Case, Improved Ability to Track & Query Identified Variants
BOSTON and LEUVEN, Belgium - Cartagenia, the world leader in software-based workflow support for genetic variant assessment, lab reporting, and integration of diagnostic knowledge-bases, today announced that the Human Genetics Laboratory, part of the Munroe-Meyer Institute for Genetics and Rehabilitation (MMI) at the University of Nebraska Medical Center (UNMC), has selected the Cartagenia Bench platform genetics diagnostics solution for use at its healthcare laboratory. Cartagenia Bench is a cloud-based platform that allows genetics labs and clinicians to analyze, interpret, report, and share genomic variants in routine clinical diagnostics.
Jennifer N. Sanmann, PhD, MB(ASCP)(CM)CG(CM), a representative of the Human Genetics Laboratory at UNMC, noted that its laboratory's adoption of Bench has helped them track their lab findings in a single, well-annotated database and has led to significantly reduced report turnaround times.
"Our laboratory's experience with Cartagenia has been a very positive one," Dr. Sanmann said. "The transition from our internally developed system to Bench CNV and Bench NGS went smoothly and was well supported by the Cartagenia team. It has been our experience that the Bench modules have reduced significantly the amount of analysis time per case and have improved our ability to track and query identified variants."
"The boundary between molecular genetics and cytogenetics testing is fading. NGS technology is being adopted to determine structural events; public registries such as ClinVar collect both CNVs and SNPs; and most importantly, structural variation and molecular variation are more and more often used to jointly explain the patient phenotype, and reach a diagnosis," says Steven Van Vooren, Product Marketing Director at Cartagenia. "At Cartagenia, we strongly believe in a 'single platform' approach, where joint clinical interpretation of structural and molecular events comes natural, and is agnostic of the technology used to pick up variants."
The Cartagenia Bench platform is a clinical-grade, medical device software platform that supports the assesment and reporting of structural variants such as copy number gains, losses, and changes in zygosity, as well as molecular events such as single nucleotide events, and small insertions and deletions.
"We see strong growth in labs adopting both our NGS and CNV modules on the Bench platform, and bringing together structural and molecular variants in their interpretation and reporting," says Herman Verrelst, CEO of Cartagenia. "At Cartagenia, we want to facilitate this evolution, allowing labs to automate their workflow as much as possible and use the time won to focus on the clinical setting in which to assess and report variants - whether postnatal, prenatal or in oncology."
About UNMC
UNMC's Human Genetics Laboratory is a CAP and CLIA accredited full service cytogenetic and molecular genetic laboratory combining comprehensive genetic testing with personalized clinical consultation to provide the very best in genetic medicine to every client and patient served. As genetic disease continues to become more widely identifiable, customized technology and new assays are developed and validated, meeting expanding clinician and patient needs through advancements in systems, software, and diagnoses. In addition to diagnostic and research studies in the areas of perinatal, postnatal, and oncology testing, comprehensive services at UNMC include clinical evaluation by licensed genetic counselors and board certified medical geneticists. Visit unmc.edu/geneticslab to learn more.
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University of Nebraska Medical Center Selects Cartagenia Bench Platform for NGS and Array ...
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2014 ACMG Foundation/Signature Genomic Labs, PerkinElmer Inc. Travel Award winner
Posted: at 8:45 pm
PUBLIC RELEASE DATE:
1-Apr-2014
Contact: Kathy Beal kbeal@acmg.net 301-238-4582 American College of Medical Genetics
Jun Shen, PhD was honored as the 2014 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer, Inc. Travel Award at the American College of Medical Genetics and Genomics (ACMG) 2014 Annual Clinical Genetics Meeting in Nashville, TN.
Dr. Shen was selected to receive the award for her platform presentation, "Clinical Validation of a Novel Combinatorial Algorithm that Predicts Pathogenicity of Human Missense Variants with High Accuracy."
Dr. Shen completed her PhD in Neurobiology at Harvard University, and completed her Postdoctoral Fellowship in Neurobiology with a focus on the inner ear at Howard Hughes Medical Institution/Harvard Medical School. Dr. Shen received her Bachelor of Arts in Biochemistry, Molecular Biology and Computer Science at Dartmouth College. She is currently an Instructor in Pathology at Brigham and Women's Hospital and Harvard Medical School and an Assistant Laboratory Director, Laboratory for Molecular Medicine, Partners HealthCare Center for Personalized Genetic Medicine.
The ACMG Foundation/Signature Genomics Travel Award is given to an ACMG Trainee member whose abstract submission was chosen as a platform presentation during the ACMG Annual Clinical Genetics Meeting. The ACMG Program Committee selects the Travel Award recipient based on scientific merit. In recognition of the selected presentation, Signature Genomics covers the travel costs for the recipient to the ACMG meeting.
"The Foundation for Genetic and Genomic Medicine is grateful to Signature Genomics for its continued generous support of the development of medical genetic researchers through this Travel Award," said Bruce R. Korf, MD, PhD FACMG, president of the ACMG Foundation for Genetic and Genomic Medicine.
"Signature Genomics is pleased to support the recognition of young researchers like Dr. Shen who are working in the field of genetics and genomics. This presentation is just one of the many outstanding presentations at the 2014 ACMG Annual Meeting," said Beth Torchia, PhD, FACMG, Technical Laboratory Director at Signature Genomics from PerkenElmer, Inc.
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2014 ACMG Foundation/Signature Genomic Labs, PerkinElmer Inc. Travel Award winner
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Gorilla Warfare — The Crown / Young Kannon Vs. DNA : Young Kannon Recaps His Battle With DNA – Video
Posted: at 8:44 pm
Gorilla Warfare -- The Crown / Young Kannon Vs. DNA : Young Kannon Recaps His Battle With DNA
Gorilla Warfare -- The Crown / Young Kannon Vs. DNA : Young Kannon Recaps His Battle With DNA.
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Gorilla Warfare -- The Crown / Young Kannon Vs. DNA : Young Kannon Recaps His Battle With DNA - Video
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