Monthly Archives: March 2014

Genome: A healthcare revolution – Newsnight – Video

Posted: March 25, 2014 at 7:43 am


Genome: A healthcare revolution - Newsnight
Rohan Silva investigates the potential of the human genome in creating a personalised healthcare revolution Follow @BBCNewsnight on Twitter https://twitter.c...

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Genome: A healthcare revolution - Newsnight - Video

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INOKI GENOME FIGHT 1 – Video

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INOKI GENOME FIGHT 1
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IBM's Watson helps genome research

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IBM says it is joining a 'genomic medicine' initiative, using its Watson supercomputer to deliver customised treatment options for cancer patients.

The US computing group said on Wednesday it was teaming with the New York Genome Center in a program to help doctors develop treatments tailored to each patient's genetic makeup.

The first phase will help oncologists find treatments for patients with glioblastoma, an aggressive and malignant brain cancer that kills more than 13,000 people in the United States each year.

The supercomputer will be used to scan medical journals, new studies and clinical records and correlate those with a patient's genetic mutations.

'Clinicians lack the tools and time required to bring DNA-based treatment options to their patients,' said a statement from IBM and the Genome Center.

'This joint NYGC Watson initiative aims to speed up this complex process, identifying patterns in genome sequencing and medical data to unlock insights that will help clinicians bring the promise of genomic medicine to their patients.'

Because Watson can continually 'learn' from new data, the initiative aims to update databases that give doctors the best treatment options.

'Since the human genome was first mapped more than a decade ago, we've made tremendous progress in understanding the genetic drivers of disease,' said Robert Darnell, president and scientific director of the centre.

'The real challenge before us is how to make sense of massive quantities of genetic data and translate that information into better treatments for patients.

'Applying the cognitive computing power of Watson is going to revolutionise genomics and accelerate the opportunity to improve outcomes for patients with deadly diseases.'

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Eczema Stress – How To Cure Eczema Stress Easily – Video

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Eczema Stress - How To Cure Eczema Stress Easily
Cure Eczema Stress Easily ,Read this : http://bit.ly/OAMCRo While you cannot always control this, try to avoid sweating as much as possible. If you work out ...

By: Jay Sornint

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Eczema – KidsHealth

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Most kids get itchy rashes at one time or another. But eczema can be a nuisance that may prompt scratching that makes the problem worse.

The term eczema refers to a number of different skin conditions in which the skin is red and irritated and occasionally results in small, fluid-filled bumps that become moist and ooze. The most common cause of eczema is atopic dermatitis, sometimes called infantile eczema although it occurs in infants and older children.

The word "atopic" describes conditions that occur when someone is overly sensitive to allergens in their environment such as pollens, molds, dust, animal dander, and certain foods. "Dermatitis" means that the skin is inflamed, or red and sore.

Kids who get eczema often have family members with hay fever, asthma, or other allergies. Some experts think these kids may be genetically predisposed to get eczema, which means characteristics have been passed on from parents through genes that make a child more likely to get it.

About half of the kids who get eczema will also someday develop hay fever or asthma themselves. Eczema is not an allergy itself, but allergies can trigger eczema. Some environmental factors (such as excessive heat or emotional stress) can also trigger the condition.

About 1 out of every 10 kids develops eczema. Typically, symptoms appear within the first few months of life, and almost always before a child turns 5. But the good news is that more than half of the kids who have eczema today will be over it by the time they're teenagers.

Signs and symptoms of eczema can vary widely during the early phases. Between 2 and 6 months of age (and almost always before they're 5 years old), kids with eczema usually develop itchy, dry, red skin and small bumps on their cheeks, forehead, or scalp. The rash may spread to the extremities (the arms and legs) and the trunk, and red, crusted, or open lesions may appear on any area affected.

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Mind, body & Soul: Foods for nourishing the skin

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Mind, body & Soul: Foods for nourishing the skin

2:33pm Monday 24th March 2014 in Health, Beauty & Wellbeing By Sally Duffin

Spring sunshine hints at the warm summer months to come and thoughts of peeling back our layers of winter clothing.

Your skin can really suffer during winter, being stifled under vests and thick jumpers or exposed to harsh cold weather and by spring it can feel dry, flaky and dull.

Natural skincare products are great for cleansing and moisturising whilst eating foods that nourish your skin from within can help redress a wide variety of chronic conditions including sensitive skin, acne, eczema and psoriasis.

Your skin is covered by a fine layer of natural oils which protect it from damage and retain moisture in the top layer of skin cells. This natural oil barrier is affected by harsh skincare products and a diet low in healthy fats and water.

Including cold pressed flaxseed oil in salad dressings, smoothies or yoghurt, drinking plenty of water and eating fresh oily fish, nuts and seeds several times a week tops up your levels of healthy fats and maintains your skins hydration and oil balance.

Even if you have oily skin you still need these fats otherwise your skin produces more oil to compensate for a lack of them.

Eczema is derived from the Greek work exzein which literally means to boil over and skin looks sore, red and inflamed. From a naturopathic viewpoint, your skin is a reflection of what is going on inside the body and if your liver and bowels are not getting rid of wastes properly, this will affect your skin!

Food intolerances are frequently a factor in both eczema and psoriasis as they can trigger your immune system and produce skin inflammation.

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Jill Reveals Her Fight Against Plaque Psoriasis – Video

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Jill Reveals Her Fight Against Plaque Psoriasis
Watch Jill #39;s uplifting plaque psoriasis story. Jill has been battling moderate to severe plaque psoriasis since she was 23. She always felt she had to wear l...

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TCM Treatment For Psoriasis Of Sami From Saudi Arabia – Video

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TCM Treatment For Psoriasis Of Sami From Saudi Arabia
TCM Treatment For Psoriasis Of Sami From Saudi Arabia.

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Forget drugs: You can beat psoriasis by TALKING about it

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Toby Hadoke, 40, from London has suffered with psoriasis since childhood Has recently found a surprising treatment - cognitive behavioural therapy

By Grace Mccann

PUBLISHED: 20:12 EST, 24 March 2014 | UPDATED: 20:14 EST, 24 March 2014

Toby Hadoke has suffered with psoriasis since childhood. The condition, which causes red, scaly patches of skin, is distressing and can be painful.

'At its worst, I felt like I'd been stung by a thousand bees,' says Toby, a 40-year-old comedian and writer from north London.

But recently he's found a surprising treatment that has transformed his symptoms. Much of his skin used to be covered in flaky patches. Today, these areas are merely slightly pink and dry.

Toby Hadoke, 40, from London has suffered with psoriasis since childhood and has recently found a treatment

The difference is not down to a new ointment but, he says, it's thanks to a form of talking therapy, known as cognitive behavioural therapy (CBT).

'I tried everything - Chinese medicine, mud from the Dead Sea, bathing in lavender,' says Toby. 'But CBT has helped massively - I finally feel I'm in control of my psoriasis.'

It may seem surprising that a psychological treatment could have such a marked effect on a physical condition, but it is increasingly being used outside the mental health field.

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Forget drugs: You can beat psoriasis by TALKING about it

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Deletion of FAT10 gene reduces body fat, slows down aging in mice

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PUBLIC RELEASE DATE:

24-Mar-2014

Contact: Andrea Grossman 617-636-3728 Tufts University, Health Sciences Campus

Boston, MA [March 24, 2014, 3:00 p.m. EDT] A single gene appears to play a crucial role in coordinating the immune system and metabolism, and deleting the gene in mice reduces body fat and extends lifespan, according to new research by scientists at the Jean Mayer USDA Human Nutrition Research Center (USDA HNRCA) on Aging at Tufts University and Yale University School of Medicine. Their results are reported online today in the Proceedings of the National Academy of Sciences.

Based on gene expression studies of fat tissue conducted at the USDA HNRCA, the Tufts University researchers initiated studies of the role of FAT10 in adipose tissue and metabolism. "No one really knew what the FAT10 gene did, other than it was 'turned on' by inflammation and that it seemed to be increased in gynecological and gastrointestinal cancers." said co-author Martin S. Obin, Ph.D., an adjunct scientist in the Functional Genomics Core Unit at the USDA HNRCA at Tufts University. "Turning off the FAT10 gene produces a variety of beneficial effects in the mice, including reduced body fat, which slows down aging and extends lifespan by 20 percent."

Typically, mice gain fat as they age. The authors observed that activation of the FAT10 gene in normal mice increases in fat tissue with age. Mice lacking FAT10 consume more food, but burn fat at an accelerated rate. As a result, they have less than half of the fat tissue found in normal, aged mice. At the same time their skeletal muscle ramps up production of an immune molecule that increases their response to insulin, resulting in reduced circulating insulin levels, protection against type 2 diabetes and longer lifespan.

The authors note that eliminating FAT10 will not fully address the dilemma of aging and weight gain. "Laboratory mice live in a lab under ideal, germ-free conditions," said Obin, who is also an associate professor at the Friedman School of Nutrition Science and Policy at Tufts University. "Fighting infection requires energy, which can be provided by stored fat. Mice without the FAT10 gene might be too lean to fight infection effectively outside of the laboratory setting. More research is needed to know how to achieve that balance in mice and then hopefully, at some point, people."

The possibilities for future research of FAT10 are exciting. Recent high-profile studies reported that FAT10 interacts with hundreds of other proteins in cells. Now the Tufts and Yale researchers have demonstrated that it impacts immune response, lipid and glucose metabolism, and mitochondrial function.

"Now there is dramatic road map for researchers looking at all of the proteins that FAT10 gets involved with," said co-first and corresponding author Allon Canaan, Ph.D., an associate scientist in the Department of Genetics at Yale. "Blocking what FAT10 does to coordinate immunity and metabolism could lead to new therapies for metabolic disease, metabolic syndrome, cancer and healthy aging, because when we knock it out the net result is mice live longer."

Canaan and colleagues initially developed the FAT10-deficient mouse to study the role of FAT10 in sepsis. In an attempt to increase sensitivity for sepsis, Canaan aged the FAT10 knockout mice and made the discovery that mice lacking the gene were lean and aged more slowly. The mice appear younger and more robust than comparably-aged normal mice, have better muscle tone, and do not develop age-related tumors.

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Deletion of FAT10 gene reduces body fat, slows down aging in mice

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