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Monthly Archives: September 2013
How to Recover Deleted Photos from HTC DNA – Video
Posted: September 4, 2013 at 12:48 pm
How to Recover Deleted Photos from HTC DNA
Free download the powerful HTC Droid DNA Data Recovery - Dr.Fone for Android: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/android-data...
By: Selena Lee
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How to Recover Deleted Photos from HTC DNA - Video
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How to Recover Deleted Music from HTC DNA – Video
Posted: at 12:48 pm
How to Recover Deleted Music from HTC DNA
Lost your music files on HTC Droid DNA? Here is the best way for you to get them back: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/and...
By: Selena Lee
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How to Recover Deleted Music from HTC DNA - Video
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How to Recover Deleted Files from HTC DNA – Video
Posted: at 12:48 pm
How to Recover Deleted Files from HTC DNA
Here is the best way to retrieve your deleted or lost files from HTC Droid DNA for you: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/an...
By: Selena Lee
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How to Recover Deleted Files from HTC DNA - Video
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How to Recover Deleted Videos from HTC DNA – Video
Posted: at 12:48 pm
How to Recover Deleted Videos from HTC DNA
Download HTC DNA Droid Videos Recovery program for free to retrieve your lost videos: [Dr.Fone for Android (Windows)] http://www.phone-data-recovery.org/andr...
By: Selena Lee
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How to Recover Deleted Videos from HTC DNA - Video
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Darkness, Deception, DNA – Video
Posted: at 12:48 pm
Darkness, Deception, DNA
Lisa Bradford had two beautiful children and a charming, doting husband, Dennis. She thought she had a happily ever after ahead of her. However, when Dennis ...
By: idfullepisodes
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Darkness, Deception, DNA - Video
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Dizaster: DNA Made Chilla Jones Look Like an Ant – Video
Posted: at 12:48 pm
Dizaster: DNA Made Chilla Jones Look Like an Ant
http://www.vladtv.com/ - Dizaster opened up on his history with battling in this clip from his exclusive interview with VladTV. Diz explained that he began r...
By: djvlad
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Dizaster: DNA Made Chilla Jones Look Like an Ant - Video
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Wanessa DNA Tour – em Teresina. – Video
Posted: at 12:48 pm
Wanessa DNA Tour - em Teresina.
Wanessa DNA Tour - em Teresina-PI no Villa Rio.
By: ThiagoTify
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Wanessa DNA Tour - em Teresina. - Video
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DNA CONECTIONS – Video
Posted: at 12:48 pm
DNA CONECTIONS
Dinamismo, sin importar que edad, solo en DNA CONECTIONS...
By: Christian Dasilva
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DNA CONECTIONS - Video
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'Highly programmable' DNA cubes could be used for drug delivery
Posted: at 12:48 pm
3D cages made from strands of DNA could be used as a nanotechnology solution for drug delivery.
Cubes of DNA, with molecular tentacles, or chains, attached on each corner, spontaneously create water-repellant carriages that could be used to carry drugs.
In research carried out at McGill University in Canada, lipid-tipped DNA chains attached to DNA cubes folded back inside, creating places for hydrophobic molecules to be carried. The research is detailed in a paper published in Nature Chemistry on 1 September.
Importantly, the drugs are released by snipping off the tentacles. By designing the cages with specific delivery sites in mind, the tentacles could fall off when the cages arrive at the proper location, delivering the drugs to where they are most effective.
The potential for DNA cages in drug delivery partly lies in their ability to form a variety of cell-like stable structures. As a 2013 paper from Universite Bordeaux Segalen noted, "the ability of DNA to form predicatble and complex nano-architectures is virtually unlimited."
"We are able to create DNA cages with any geometry, size or shape, and that's unique among drug delivery vehicles," says Hanadi Sleiman, who led the research. "They are extremely programmable."
Finding novel ways of inducing these cages to carry a cargo and then release it at the appropriate point is currently a very active area of research. This study is the first time molecules that don't actively attach to DNA have been transported inside a DNA cage.
"[Putting molecules] in a DNA cage is difficult as the pore size is very large," says Sleiman.
To solve this problem, the team added altered DNA chains -- dendritic DNA or "D-DNA" -- to each of the corners of a DNA cube. The chains are known as "amphipiles", meaning that that they are attracted to both water and lipids. As the chains themselves have lipids on the ends, they are therefore attracted to each other.
"When there are eight amphiphiles, they engage in an intramolecular "handshake" inside the cube [] this encapsulates small molecules and releases them by DNA recognition," the team note in the paper.
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'Highly programmable' DNA cubes could be used for drug delivery
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DNA 'cages' hope for drug delivery
Posted: at 12:48 pm
Tiny "cages" of DNA can be used to deliver drugs to diseased cells, new research has shown.
The discovery opens up new avenues for highly-precise targeted treatments.
Scientists are conducting cell and animal studies to see if the DNA "smart bombs" can be used to tackle leukaemia and prostate cancer.
Lead scientist Professor Hanadi Sleiman, from McGill University in Canada, said: "This research is important for drug delivery, but also for fundamental structural biology and nanotechnology."
DNA carries all the genetic information of living organisms, but can also be used to build microscopic structures.
Prof Sleiman's team first created cubes from short strands of DNA, then modified them with fatty lipid molecules.
The lipids created a sticky "core" within the cube that could hold cargo such as a drug.
Scientists from the same laboratory have previously shown that gold nanoparticles can be loaded and released from DNA tubes.
The "cages" can trap much smaller particles than gold, making them suitable for medical applications.
A major advantage is that they can be designed to release drugs in the presence of a specific genetic code sequence.
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DNA 'cages' hope for drug delivery
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