Daily Archives: July 4, 2013

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NEW YORK (Reuters Health) - In a new review of previous research, children who took antibiotics in their first year of life were about 40 percent more likely to develop eczema, an itchy skin disorder.

Kids' exposure to antibiotics taken by their mothers during pregnancy was not tied to the common rash, however, according to the results published in the British Journal of Dermatology

Experts said the new study supports the idea that antibiotics destroy intestinal microbes that play an important role in the immune system's development after birth.

The "hygiene hypothesis" suggests that babies and children whose immune systems are not exposed to enough challenges because their environment is too clean may be prone later in life to immune overreactions like allergies and asthma.

This study brings us closer to understanding the possible link between antibiotics and eczema, Dr. Ruchi Gupta, director of the program for maternal and child health at Northwestern School of Medicine in Chicago, told Reuters Health by email.

"They may be linked through the hygiene hypothesis," said Gupta, who was not involved in the new study. Throwing one element of the delicate developing immune system off-kilter could result in allergic skin reactions like eczema, she said.

Eczema is a common skin disorder, especially among children, marked by itchy, red skin. Between 10 and 20 percent of children experience symptoms of the disease, and more than half of them continue to have symptoms into adulthood, according to the National Institutes of Health.

Patients are often prescribed steroid medications to treat the problem.

Previous research had suggested that early life exposure to antibiotics may lead to an increased risk for eczema, but the new review is the first to consolidate available results from several studies.

Researchers led by Dr. Teresa Tsakok of Guy's and St Thomas' Hospital NHS Foundation Trust in London, UK, evaluated the results of 20 studies of antibiotic use, either prenatally or in the first year of life, in connection with later skin problems.

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Study: Children given antibiotics in first year were more likely to develop eczema