Monthly Archives: June 2013

Frost & Sullivan Applauds geneOnyx for its DNA Testing Solution for the Personalized Cosmeceuticals Market

Posted: June 20, 2013 at 9:44 am

- The company integrated on-the-spot DNA microchip-based test with a cloud-based server and gene-mapping engine to offer a rapid and robust cosmeceuticals solution

MOUNTAIN VIEW, California, June 20, 2013 /PRNewswire/ -- Based on its recent analysis of the personalized cosmeceuticals market, Frost & Sullivan recognizes geneOnyx Limited with the 2013 European Frost & Sullivan Award for New Product Innovation. geneOnyx leverages a DNA testing platform originally used for medical point-of-care testing to create an on-the-spot genetic test for anti-aging cosmetics.

geneOnyx's test requires only a single-step DNA collection procedure from saliva to examine single nucleotide polymorphisms (SNPs)or genetic variationsin key genes relating to important skin biochemical pathways. The sample is placed on a rapid lab-on-chip system, which is connected to a cloud-computing device linked to CosMos(TM), geneOnyx's patent-pending, cloud-based data analysis engine and ingredient library.

In 30 minutes, the system maps the personalized profile of the individual's genetic variations with compatible active ingredients and recommends a customized anti-aging serum that will be most effective for the individual. The DNA microchip will be securely disposed of immediately to ensure the confidentiality of the customer's profile.

"The DNA microchip is portable, resembling a USB memory stick, and enables testing outside the laboratory environment," said Frost & Sullivan Industry Analyst Vin Nee Lim. "geneOnyx DNA testing harnesses DNA Electronics' proprietary Genalysis(R) technology; geneOnyx(TM) obtained a worldwide exclusive license from DNA Electronics in 2012 for utilizing this technology in the cosmeceuticals sector."

The geneOnyx test is the first over-the-counter personalized genetic test. Dermatologists and cosmeticians find it highly useful in recommending skincare products with specific ingredients. As the test is user-friendly, they can easily be carried out by non-scientific trained personnel and conveniently performed in a retail setting.

geneOnyx's product will have a significant impact on the cosmetic industry by enabling an end-to-end customer service.

"The company is set to launch a flagship store in London with its own skincare range, developed in association with the genetic testing technology, providing customers with both personalized recommendations and a skincare regime solution," noted Lim. "geneOnyx's current services are focused on anti-aging skincare, but the testing system's application will extend to health and wellness as well."

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.

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Frost & Sullivan Applauds geneOnyx for its DNA Testing Solution for the Personalized Cosmeceuticals Market

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Analyzing Genome Scale Methylome Data Sets GSE44350) – Video

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Analyzing Genome Scale Methylome Data Sets GSE44350)
GSE44350 is composed 3 sub-series. Two are based on Illumina human methylation beadchips, 27000 and 450000 methylation sites respectively. 24 samples were ...

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Waldorf Rocket Synth being powered by Genome MIDI Sequencer on my iPad – Video

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Waldorf Rocket Synth being powered by Genome MIDI Sequencer on my iPad
Very easy to access CC #39;s using Genome as always.

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Say Hello to GMOs – Changing the Human Genome One Meal at a Time – Video

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Say Hello to GMOs - Changing the Human Genome One Meal at a Time

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How to download the human genome – DNA (sketch) – Video

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How to download the human genome - DNA (sketch)
What happens when human DNA falls into the public domain? Writer Gregg Lopez Cast Matthew Harris Gregg Lopez Brent Pope.

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$1,000 genome a mirage?

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Years of talk about cutting the price of sequencing a human genome to $1,000 has made one prominent genomics guru more than a little cranky. Mick Watson wrote on his blog Tuesday that such talk is "utter crap."

Watson, a genomicist/bioinformatician who heads a genomics center at the Roslin Institute, isn't at all sheepish about voicing his disdain for popular and scientific media accounts of the impending $1,000 genome. What set him off was a marketing statement in the new journal PeerJ that talked of a $99 genome.

Two even more prominent genomics experts I contacted for comment, J. Craig Venter and Eric Topol, say Watson is both right and wrong. Right that the full cost of a human genome today is much more than $1,000. Wrong because the price of that genome continues to drop, so a $1,000 genome is indeed fast approaching.

But first, some details on Watson's complaint.

Watson says just the cost of chemicals for doing a medical-grade human genome runs to more than $1,000. (Because today's DNA sequencers are fast but far from error-free, genomes must be run many times -- at least 30x is the standard -- to eliminate errors. Venter and colleagues learned that the hard way when they synthesized a bacterial genome, put it in a host cell that had its DNA removed, and nothing happened. An apparently trivial mistake -- one base pair deleted -- made the whole genome fail. They tried again and succeeded, once they had fixed the error. That's the difference between research-grade and medical-grade genomes, Venter says.)

Throw in equipment depreciation, data storage, overhead, staff time and the need for genome sequencing companies to make money, Watson says, and the current cost is more than $2,000.

"Obviously, Illumina dont charge themselves list price for reagents, and nor do LifeTech, so its possible that they themselves can sequence 30x human genomes and just pay whatever it costs to make the reagents and build the machines; but this is not reality and its not really how sequencing is done today," Watson wrote on his blog. "These guys want to sell machines and reagents, they dont want to be sequencing facilities, plus they still have to pay the staff, pay the bills, make a profit and return money to investors."

Apples and oranges, Venter said.

"Sequencing cost is the only thing anyone measures and is approaching $1k in theory, the accuracy of whole genomes is not of diagnostic quality, and the informatics cost more than the sequencing," Venter said by email. "I have been saying this for years."

Venter cited a 2011 article he wrote for Science pointing out the progress and challenges that remain.

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Dry Skin and Eczema Treatment – Video

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Dry Skin and Eczema Treatment

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Eczema Dermatitis) – Video

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Eczema Dermatitis)

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Babies given antibiotics before they’re one ‘are more prone to eczema’: Drugs increase risk by 40%

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By Jenny Hope

PUBLISHED: 19:34 EST, 19 June 2013 | UPDATED: 01:42 EST, 20 June 2013

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Babies given antibiotics before they are a year old are more likely to develop eczema, say British researchers.

After years of debate about a possible link, a huge study shows taking the drugs in the first year of life increases the chances of developing the skin disorder by 40 per cent.

Each additional course of antibiotics further raises the risk of eczema which affects one in five children in the UK by 7 per cent.

Babies given antibiotics before they are a year old are more likely to develop eczema, say British researchers

About 2.4million of the UKs 12million children have been diagnosed with the disease, caused by an over-active immune system and resulting in dry and itchy skin.

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UK & World News: Baby antibiotics ‘link to eczema’

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Jun 20 2013

The use of antibiotics in the first 12 months of life may increase the chance of developing eczema by up to 40%, according to a new study.

The report also found that each additional course of antibiotics further raises the risk of eczema by 7%.

Researchers reviewed existing data from 20 studies that explored the link between antibiotic exposure prenatally and in the baby's first year, and the subsequent development of eczema. They also examined whether the number of antibiotic courses affected the probability of developing the skin condition.

They found that children with eczema are more likely to have been treated with antibiotics in the first year of life, but not prenatally.

One of the study's authors, Dr Teresa Tsakok of Guy's and St Thomas' NHS Foundation Trust in London, said: "One potential explanation is that broad-spectrum antibiotics alter the gut microflora and that this in turn affects the maturing immune system in a way that promotes allergic disease development."

The paper's senior author, Dr Carsten Flohr of King's College London and Guy's and St Thomas', added: "A better understanding of the complex relationship between antibiotic use and allergic disease is a priority for clinicians and health policymakers alike, as determination of a true link between antibiotic use and eczema would have far-reaching clinical and public health implications."

The study, which was published in the British Journal of Dermatology, was also carried out by researchers from the University of Nottingham and the Aberdeen Royal Infirmary.

The paper added a note of caution, explaining that the use of antibiotics may be a consequence of more infections in children with eczema.

Nina Goad, of the British Association of Dermatologists, said: "Eczema is our most common skin disease, affecting one in every five children in the UK at some stage and causing a significant burden to the patient and the health service. Allergic diseases including eczema have increased over past decades, particularly for children in high-income countries, but the causes for this are not fully understood.

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