Daily Archives: June 27, 2013

Live 9 205: Live DNA - 10. Remixing Live
Additional videos for this title: http://j.mp/12QnTO4 Live 9 205: Live DNA! by Noah Pred Video 10 of 22 for Live 9 205: Live DNA! Ableton Certified Trainer N...

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Live 9 205: Live DNA - 10. Remixing Live - Video

LIVE ~ Me the 12D Beings ~ Includes a DNA Fine Tuning
2013-06-20 2nd journal, Mayan day 3 Imix / Crocodile or Alligator NOTE: TO ENJOY THE MANY LINKS, PLEASE GO TO THE WRITTEN JOURNAL WHERE THEY ARE LIVE - these...

By: TheseEyesGod

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LIVE ~ Me

SPECIES, GODS, ALTERED DNA alien female hands 02 / frames
Original source - https://www.youtube.com/watch?v=5I5nmEdt94Q.

By: Pocholo986

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SPECIES, GODS, ALTERED DNA alien female hands 02 / frames - Video

I don #39;t need DNA to perform a curse
jo, this ain #39;t me. got it mailed and decided to upload it. If you want to hate on this guy, go to his channel, whereever it is. It #39;s name is "Vampiric Spektor"

By: BugBettler

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I don't need DNA to perform a curse - Video

"Voluntary" Blood and DNA Roadblocks #N3
PELL CITY, Alabama -- Motorists in Alabama #39;s St. Clair and Bibb counties were required to go through nighttime checkpoints at several locations on May 31 and...

By: NextNewsNetwork

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"Voluntary" Blood and DNA Roadblocks #N3 - Video

SMACK/URL N.O.M.E 3 DNA vs Chilla Jones intro
via YouTube Capture.

By: drpower1965

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SMACK/URL N.O.M.E 3 DNA vs Chilla Jones intro - Video

UCSF Study Identifies Thousands of Previously Unknown RNA Molecules

Newswise A new UC San Francisco study highlights the potential importance of the vast majority of human DNA that lies outside of genes within the cell.

The researchers found that about 85 percent of these stretches of DNA make RNA, a molecule that increasingly is being found to play important roles within cells. They also determined that this RNA-making DNA is more likely than other non-gene DNA regions to be associated with inherited disease risks.

The study, published in the free online journal PLOS Genetics on June 20, 2013, is one of the most extensive examinations of the human genome ever undertaken to see which stretches of DNA outside of genes make RNA and which do not.

The researchers senior author and RNA expert Michael McManus, PhD, UCSF associate professor of microbiology and immunology and a member of the UCSF Diabetes Center, graduate student Ian Vaughn, and postdoctoral fellow Matthew Hangauer, PhD identified thousands of previously unknown, unique RNA sequences.

Now that we realize that all these RNA molecules exist and have identified them, the struggle is to understand which are going to have a function that is important, McManus said. It may take decades to determine this.

The RNA most familiar from textbooks is the messenger RNA that is transcribed from DNA in genes and that encodes the amino acid building blocks of proteins. The transcription of messenger RNA from DNA is a key step in protein production. The rest of the DNA on the cells chromosomes was once thought not to be transcribed into RNA, and was referred to as junk DNA.

Today, scientists estimate that only 1.5 percent of the genome consists of genes, McManus said. But over the last two decades other kinds of RNA have been identified that are transcribed from DNA outside of gene regions. Some of these RNA molecules play important biological roles, but scientists debate whether few or most of these RNA molecules are likely to be biologically significant.

Among the RNA transcribed by the DNA outside of genes, the UCSF researchers identified thousands of previously unknown RNA sequences of a type called lincRNA. So far, only a handful of lincRNA molecules are known to play significant roles in human biology, McManus said.

Previous research has shown that lincRNAs can have diverse functions. Some control the activity of genes that encode proteins. Others guide protein production in alternative ways.

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DNA Found Outside Genes Plays Largely Unknown, Potentially Vital Roles

Researchers have unraveled the genetic code of a wild horse that loped across the frozen Yukon about 700,000 years ago, making it the oldest creature by far to reveal its DNA to modern science.

Until recently, experts believed it was impossible to recover useful amounts of DNA from fossils that old. The previous record holder for oldest genome belonged to a polar bear that lived more than 110,000 years ago. The horse sequence, described Wednesday in the journal Nature, amounts to a dramatic increase in how far back scientists can peer into the biochemical history of advanced life.

The DNA was extracted from a 6-inch slice of a fossilized horse leg bone that was found nine years ago. Under normal conditions, DNA begins to degrade soon after death. But this bone was preserved in permafrost at Thistle Creek in Canada's Yukon Territory.

Dating techniques revealed that the animal lived in an epoch when woolly mammoths, saber-toothed cats and giant beavers shared turf with ancestral humans.

The work "opens great perspectives as to the level of details we can reconstruct of our origins and the evolutionary history of every animal on the planet," said study leader Ludovic Orlando of the Center for GeoGenetics at the Natural History Museum of Denmark.

Orlando and an international team of collaborators pieced together even the tiniest of DNA fragments recovered from the bone. Such genetic puzzle assembly generally includes multiple samples from each part of the genome, sometimes as many as five or 10. In this case, the so-called coverage was just 1.12.

That's not enough detail to say much about what the horse looked like, said Eske Willerslev, an evolutionary biologist at the Natural History Museum of Denmark who worked on the study. Team members suggested the horse was about the size of a modern Icelandic or Arabian horse, though it probably was less muscular, and perhaps slower.

"If they were fast runners, it was not because of the same genes we know of today," Orlando said.

As part of the genetic sleuthing, the team also sequenced the DNA of a 43,000-year-old horse fossil, five modern domesticated horses, a wild Przewalski's horse native to the Mongolian steppes, and a donkey from the Copenhagen Zoo named Willy.

By comparing all of these genomes, the researchers determined that the most recent common ancestor of all these species as well as zebras lived 4 million to 4.5 million years ago. That's about 2 million years earlier than previously thought, and allows for far more time for horses to have evolved into the animals we know today.

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Ancient horse is oldest creature to reveal DNA sequence

June 27, 2013

Rebekah Eliason for redOrbit.com Your Universe Online

At the center of most human cells, genomic DNA lies tucked away within a nucleus. However, a surprisingly small percentage of this DNA actually codes for genes that can be translated into proteins. In fact, some researchers estimate as much as 98 percent of this DNA seems to have a puzzling lack of purpose, leading many to refer to it as junk DNA. However, a new study from UC San Francisco now emphasizes the potentially important role of DNA residing outside of genes.

Researchers discovered that about 85 percent of the previously labeled junk DNA is vital for making RNA, a versatile molecule with many vital roles within the cell. It was also found that inherited disease risk is more likely associated with RNA-making DNA than other non-gene types of DNA.

As one of the broadest studies of the human genome ever performed to identify RNA-making DNA outside of genes, thousands of previously unidentified RNA sequences were discovered.

Michael McManus, associate professor of microbiology and immunology at the University of California San Francisco and a member of the UCSF Diabetes Center explained these findings saying, Now that we realize that all these RNA molecules exist and have identified them, the struggle is to understand which are going to have a function that is important. It may take decades to determine this.

Messenger RNA, or mRNA, is the most commonly discussed type and is transcribed from genomic DNA. It is one of the key factors in building proteins from amino acids. Previously, the rest of the DNA was not thought to transcribe RNA, but this new study is changing that idea.

It is still being debated whether RNA molecules transcribed from DNA outside of gene regions play a significant biological role or not. Scientists estimate only 1.5 percent of the human genome is made of DNA that codes for actual genes, but during the last twenty years RNA transcribed from what was thought to be junk DNA has been identified numerous times.

Researchers have discovered thousands of new lincRNA sequences, but only a few are known to be significant to human biology. Previously lincRNA has been shown to have various roles including control of the activity of genes encoding for proteins.

RNA is the Swiss army knife of molecules . . . it can have so many different functions, McManus explained.

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‘Junk DNA’ May Not Be So Worthless After All

26 June 2013 Last updated at 13:46 ET By Jonathan Ball BBC News

A fragment of a fossilised bone thought to be more than 700,000 years old has yielded the genome of an ancient relative of modern-day horses.

This predates all previous ancient DNA sequences by more than 500,000 years.

The study in the journal Nature was made possible because the bone was found preserved in Canadian permafrost following the animal's demise.

The study also suggested that the ancestor of all equines existed around four million years ago.

A remnant of the long bone of an ancient horse was recovered from the Thistle Creek site, located in the west-central Yukon Territory of Canada.

Palaeontologists estimated that the horse had last roamed the region sometime between a half to three-quarters of a million years ago.

An initial analysis of the bone showed that despite previous periods of thawing during inter-glacial warm periods, it still harboured biological materials - connective tissue and blood-clotting proteins - that are normally absent from this type of ancient material.

And this finding was significant as study co-author of the paper, Dr Ludovic Orlando from the University of Copenhagen, explained to the BBC World Service programme Science in Action.

You would be amazed how much material of this kind is actually out there... museums are full of fossil material from all over the planet

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Horse DNA oldest by 500,000 years