Daily Archives: November 12, 2012

Shing02 - Genome of Life
Couldn #39;t find it on youtube or the .mp3 itself on google, so I decided to upload it myself!From:iHateEmoPeopleszViews:3 0ratingsTime:03:45More inEntertainment

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Shing02 - Genome of Life - Video

Joy Genome Week 3
From:EchoNormanViews:0 0ratingsTime:36:32More inPeople Blogs

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Joy Genome Week 3 - Video

Sti Genome Exhaust
Short video of my Sti genome muffler on my V7 STI Prodrive. Rest of the system is a 3" Turbo back stainless xforce exhaust.From:chappell943Views:1 0ratingsTime:00:20More inAutos Vehicles

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Sti Genome Exhaust - Video

Parasites Reptilians Hybridizations Gods Species Macrobes -mind control Alien TV Programming
Reptilian Shapeshifter Draconian Evil Entities Devil Hybridization God Species Macrobes DNA Morph Meta Morphe Dimension Multidimensional Lizard Dracos Modified Genetic Experiment Aliens Metamorphism Altered Genome Energy Transformation NWO Mouth Tongue Snake Eyes Hybrid Features Physiognomy Reptar Dinosaur Crocodile Saurian Sauro Nonhuman People Exposed Televilsion Monsters Underground Laboratories Reptiliens Created Biological Weapon Tyranno Saurus Rex Tyrant MI6 James Casbolt NSA Intelligence Underground Bases Agents CIA Mind Control Matrix Smith Project Orion War Blood Ritual Space Mars Saturn Moon Ufos DraconiansFrom:Pocholo986Views:69 19ratingsTime:06:03More inEducation

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Parasites Reptilians Hybridizations Gods Species Macrobes -mind control Alien TV Programming - Video

Dana Waring: Personal Genetics Education Project (2012 GET Conference)
The GET Conference is an annual event for people working at the frontiers of human biology. We invite leading thinkers to discuss the important ways in which new genomic technologies will affect all of our lives in the coming years and to debate their technical, commercial, and societal impacts. We bring together scientists, industry leaders, entrepreneurs, practitioners, investors, researchers, and others to discuss advances in our ability to measure and understand human biology. See our website: http://www.getconference.org Annual GET Conference events are organized by PersonalGenomes.org, a 501(c)(3) charitable organization whose mission is to help make genomes useful for humankind. To learn more about PersonalGenomes.org and the Personal Genome Project please visit http://www.personalgenomes.org. Topics and themes explored at the GET Conference: Omics: personal genomes, microbiomes, immunomes, metabolomes, more Sensors: health and enviromental sensor technologies, self-tracking Policy: access, sharing, governance, privacy, IP Data IT: visualization, modeling, applications, tools Traits: measurement, interpretation, new products and practices Medicine: preventive + predictive + personalized + participatoryFrom:PersonalGenomesOrgViews:1 0ratingsTime:14:41More inScience Technology

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Dana Waring: Personal Genetics Education Project (2012 GET Conference) - Video

Semmelweis Symposium 2012, Opening ceremony
Semmelweis University is an internationally well known biomedical university. The Semmelweis Symposium is organized annually; it is the most prestigious scientific event of the university. The main topic of the Semmelweis Symposium 2012 is bdquo;Principal Questions of Genomic Medicine: Prediction, Prevention and Personalized Treatment". Personalized medicine is paving the way for a superior health care system. Our rapidly expanding knowledge of genetics and molecular biology is creating a stronger platform for us to move ahead into a future in which care is more closely tailored than ever before. New diagnostics for identifying disorders and new therapeutic possibilities are most likely to obtain their benefits in healthcare. The anticipated arrival of the $1000 genome this year will accelerate even further the changes that have begun.From:Semmelweis EgyetemViews:23 0ratingsTime:05:33More inEducation

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Semmelweis Symposium 2012, Opening ceremony - Video

METROLOGY (Part one)
METROLOGY Histrory of measuring system. The way from weights to the decryption of the human genome!!! (metrology. 1st movie) Description: This video shows how the science of metrology has been developing and why people needed the system of measurements. Nowadays Russia takes 3rd place in the world with it #39;s measuring capabilities. The future of our country depends on the quality of products we produce. Each one of us has the right to require high-quaility product. The video was created by the Federal state unitary enterprise VNII of metrological service. (official web-site of FSUE VNIIMS http://www.vniims.ruFrom:TheMetrologyViews:2 1ratingsTime:06:24More inScience Technology

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METROLOGY (Part one) - Video

Integrative Epigenomic Analysis of Translocation Positive and Negative Prostate Cancers
Reviews Genome-wide DNA methylation patterns that define distinct subgroups in cancer - Dr. Michal-Ruth Schweiger , Max Planck Institute for Molecular Genetics.From:AgilentNGSViews:0 0ratingsTime:16:45More inScience Technology

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Integrative Epigenomic Analysis of Translocation Positive and Negative Prostate Cancers - Video

MEMPHIS, Tenn., Nov. 12, 2012 /PRNewswire/ -- Research led by the St. Jude Children's Research Hospital Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with an extremely poor prognosis.

To view the multimedia assets associated with this release, please click: http://www.multivu.com/mnr/58586-st-jude-children-s-research-hospital-gene-sequencing-childhood-leukemia

The finding offers the first evidence of a mistake that gives rise to a significant percentage of acute megakaryoblastic leukemia (AMKL) cases in children. AMKL accounts for about 10 percent of pediatric acute myeloid leukemia (AML). The discovery paves the way for desperately needed treatment advances.

Investigators traced the genetic misstep to the rearrangement of chromosome 16, which brings together pieces of two genes and sets the stage for production of an abnormal protein. The fusion protein features the front end of CBFA2T3, a blood protein, and the back of GLIS2, a protein that is normally produced only in the kidney. Work that appears in the November 13 edition of the journal Cancer Cell reports that in a variety of laboratory models the CBFA2T3-GLIS2 protein switched on genes that drive immature blood cells to keep dividing long after normal cells had died. This alteration directly contributes to leukemia.

AMKL patients with the fusion gene were also found to be at high risk of failing therapy. Researchers checked long-term survival of 40 AMKL patients treated at multiple medical centers around the world and found about 28 percent of patients with the fusion gene became long-term survivors, compared to 42 percent for patients without CBFA2T3-GLIS2. Overall long-term survival for pediatric AML patients in the U.S. is now 71 percent.

"The discovery of the CBFA2T3-GLIS2 fusion gene in a subset of patients with AMKL paves the way for improved diagnostic testing, better risk stratification to help guide treatment and more effective therapeutic interventions for this aggressive childhood cancer," said James Downing, M.D., St. Jude scientific director and the paper's corresponding author. The first author is Tanja Gruber, M.D., Ph.D., an assistant member in the St. Jude Department of Oncology.

Co-author Richard Wilson, Ph.D., director of The Genome Institute at Washington University School of Medicine in St. Louis, noted: "We identified this unusual gene fusion by comparing the genome of children's healthy cells with the genome of their cancer cells. This type of in-depth exploration and analysis is crucial to finding unexpected structural rearrangements in the DNA that can lead to cancer. With this discovery, we now can search for more effective treatment options that target this precise defect."

The study is part of the Pediatric Cancer Genome Project, a three-year collaboration between St. Jude and Washington University to sequence the complete normal and cancer genomes of 600 children and adolescents with some of the most aggressive and least understood cancers. The human genome is the instruction book for assembling and sustaining a person. The instructions are packaged in the DNA molecule. Sequencing the genome involves determining the exact order of the four chemical bases that make up DNA. Human DNA is organized into 46 chromosomes.

"We focused on AMKL because no one had any idea of what caused this leukemia in most patients," Gruber said. The study excluded AMKL patients who were infants or children with Down syndrome because earlier research had linked their disease to other chromosomal rearrangements.

When researchers in this study sequenced just the genes that were switched on in the AMKL cells of 14 young patients, the scientists discovered half carried the CBFA2T3-GLIS2 fusion. Additional fusion genes were identified in five of the other patients. Each of those fusion genes occurred in a single patient. The genes involved included HOXA9 and MN1, both previously linked to leukemia, and GATA2 and FLII, which play roles in normal development of the megakaryocytic blood cells that are targeted in AMKL. Megakaryocytes produce the platelets that help blood clot.

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Gene sequencing project identifies abnormal gene that launches rare childhood leukemia