Daily Archives: November 9, 2012

The Cinderella of Genomics with Peter Leigh, Microsonic Systems – Video

Posted: November 9, 2012 at 11:43 am


The Cinderella of Genomics with Peter Leigh, Microsonic Systems
Chapters: 0:47 Sample Prep - the Cinderella of Genomics 10:10 The big market for genomics will be the clinic 12:00 A linguist learns the language of genomics 17:11 High tech and bio just learning to talk to each other 22:47 Healthcare - the macro picture BONUS: 30:50 An accidental invention Summary: This week at ASHG 2012 in San Francisco, Microsonic Systems is launching their first product, a high-throughput sample prep system for NGS. We talked with CEO, Peter Leigh, about the system which makes use of an accidental discovery made by co-founder, Vibhu Vivek, when he was a grad student at the University of Hawaii (see bonus section at the end). Peter is an illustrative speaker who has had along career in the life sciences. He talks of the coming revolution of genomic medicine, saying that the new technologies such as whole genome sequencing are going to do for the 21st century what antibiotics did for the 20th century. His companies focus is sample prep, a laborious process that must be carried out with sequencing, but which doesn #39;t get much attention. In one study, Peter says, they reduced the time it takes to prepare NGS libraries from 10 days down to 1 and 1/2 days. He calls sample prep the Cinderella of Genomics.From:mendelspodViews:0 0ratingsTime:33:56More inScience Technology

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Scientists Predict Eugenics Society Within 5 Years – Video

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Scientists Predict Eugenics Society Within 5 Years
*PLEASE READ DESCRIPTION* FAIR USE Professor Armand Leroi, of Imperial College London, predicts that the ever declining cost of DNA testing means that we may be heading toward a society that is based on genetic superiority. "The search for an essence is a 2000-year-old myth. What we are left with is a sense of capacity and the role of genes in the way they give us these things," he added. "I am certain genome sequencing will be available on the NHS (UK health service) within our lifetimes. It is going to be very, very accessible very, very soon." http://www.medicaldaily.com http://www.britishcouncil.org erc.europa.eu Gattaca A science-fiction film set in the near future, it #39;s about a world controlled by the Gattaca Corporation, where everyone is categorized according to their DNA. Ethan Hawke stars as Vincent, a man whose genes have been deemed inferior by the powers-that-be. He dreams of traveling to space, but is considered fit only for menial jobs. He manages to take some genetic material from an angry disabled man (Jude Law) who is genetically superior. Uma Thurman is the woman who falls in love with Vincent, without knowing who he really is. Directed by Andrew Niccol. With Alan Arkin. Categories: Drama, Romance, Sci-Fi, Thriller. Year: 1997. http://www.youtube.com = = = = = = = = FAIR USE NOTICE: This Video may contain copyrighted () material the use of which has not always been specifically authorized by the copyright owner. Such material is made available to advance understanding of ...From:CreativeMessageViews:0 0ratingsTime:04:42More inEducation

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Chocolate genome research good for farmers, environment, sweet lovers

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About 70 percent of chocolate in the world comes from West Africa.

(Phys.org)With the help of information technology (IT), Penn State professor Mark Guiltinan makes the world a sweeter place.

Guiltinan is a professor of plant molecular biology in the Department of Horticulture in the College of Agricultural Sciences. He currently runs the Guiltinan Lab, where he studies crop improvement and sustainable farming methods. Guiltinan was a key player in The International Cocoa Genome Sequencing Consortium, a worldwide effort to sequence and analyze the genome of the Criollo variety of the Theobromo cacao plant, the key ingredient in high-quality chocolate. Using genome sequencing programs and computer clusters at Penn State and abroad, Guiltinan and his colleagues have mapped the cacao genome and are working to breed better, more disease-resistant cacao plants.

Despite the incredible popularity of chocolate, the cacao plant is surprisingly difficult to grow. About 70 percent of the world's chocolate comes from West Africa, where cacao farmers often live in poverty and operate small farms. The highest quality chocolate comes from the Criollo variety of the cocoa plant, a crop that is highly susceptible to disease. An outbreak of disease among these cacao plants can destroy the lives of the farmers and their local economies.

Unlike staple crops like corn and soy, cacao trees have not been researched extensively or engineered to resist disease, and many of these trees cannot yield enough cacao to meet the growing international demand for chocolate. Guiltinan and his colleagues' research aims to the study specific gene families of Criollo that relate to disease resistance. By understanding the cacao genome and ultimately breeding higher quality cacao trees, Guiltinan hopes to provide economic, social and environmental advantages for chocolate-producing nations.

"Understanding the chocolate genome will have so many benefits," Guiltinan explained. "Perennial tree crops like cacao are good for the soil. They protect the water shed and provide a habitat for insects, birds and other animals."

Guiltinan believes that improving the genetic makeup of the cacao plant is ultimately more beneficial than using pesticides, since cacao farmers are rarely able to afford pesticides or the equipment needed to administer them. Also, Guiltinan's genetic approach is more environmentally friendly.

"You can fight disease with chemicals, but genetics is really the best way to do it," Guiltinan said. "The technology is already in the DNA. You don't have to spray it on. It doesn't get washed off. You don't need spraying equipment. You don't need chemicals."

The incredible amount of research and data in Guiltinan's collection would not be possible without IT. In October 2009, Penn State researchers conducted a total of five genome sequencing runs using a computer sequencer called Roche/454 GS FLX. The sequencer is located on campus on the third floor of Wartik Laboratory. In order to use the sequencer, researchers loaded a sample of the DNA from the Criollo variety of the Theobromo cacao plant. The sequencer produced a series of image files, which then needed to be analyzed.

According to Guiltinan, sequencing the genome is not the most difficult aspect of his research. Rather, he believes the real challenge lies in analyzing the data and identifying which genes are most important in disease resistance.

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Psoriasis Eczema Diet Advice -no sugars- – Video

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Psoriasis Eczema Diet Advice -no sugars-
Psoriasis and Eczema is/ are caused by eating sugarsFrom:Mike RungrenViews:8 1ratingsTime:05:37More inEducation

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Great things to teach Eczema Kids

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Great things to teach Eczema Kids Babies BabySiging#1 from ScratchSleeves
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Acupressure Mat – Video

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Acupressure Mat
Buy from Amazon UK Site redirect.viglink.com?key=083bca13018b6acb381a415148cefb98 out=http%3A%2F%2Fwww%2Eamazon%2Eco%2Euk%2Fexec%2Fobidos%2FASIN%2FB005DXO5QE%2Fsport%5Ffab%2D21 Product Description Acupressure Mat This high quality Acupressure Mat measures 68cm x 42cm x 1.5cm. The mat itself is made out of a heavy duty cotton canvas and boasts 230 spike petals with an aggregate of 6210 spikes. These spikes are little miracle workers as they stimulate acupressure points in your body thus increasing the circulation of blood. It is also suggested that the pressure of the spikes encourages the release of endorphins thus raising general energy levels. Please do not use this mat if you are pregnant, have damaged skin or eczema, use blood thinners or suffer from haemophilia or skin cancer. The Acupressure Mat is not a medical device and if you have any medical concerns you should consult a doctor. Disclaimer Fabriano Boutique is a participant in the Amazon EU Associates Programme, an affiliate advertising programme designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon UK. Amazon and the Amazon logo are trademarks of Amazon, Inc. or its affiliates.From:delinda macdonaldViews:0 0ratingsTime:00:56More inSports

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Re’AL Promo2 – Video

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Re #39;AL Promo2
Re #39;Al is hand made with love with some of natures best ingredients. 100% Natural 100% of the time, the way nature intended. Ingredients Properties: Shea butter bull; Moisturizes face and body, and dry scalp bull; Relieves dry skin bull; Soothes minor rashes, including diaper rash bull; Minimizes skin peeling after sunburn bull; Heals blemishes and wrinkles bull; Relieves itching due to dryness bull; Soothes sunburn bull; Minimizes razor burn prior to shaving bull; Treats small skin wounds bull; Softens and heals cracking skin bull; Softens callouses on feet, especially heels bull; Prevents stretch marks from pregnancy bull; Heals minor burns bull; Treats mild to moderate eczema bull; Protects the skin, especially lips from sun and wind bull; Smoothes out skin tone bull; Prevents bumps after shaving bull; Treats acne, especially when used with African black soap bull; Easily absorbed, non-comedogenic, absorbs without blocking pores bull; Maintains and restores skin #39;s natural elasticity bull; Brings shine luster to hair Almond oil bull; Moisturizes and cleans skin bull; Lubricates skin for a smooth shave bull; Keeps skin shiny and soft Olive oil bull; Helps control dandruff and dry scalp problems bull; Heals scars and stretch marks bull; Improves skin elasticity Frankincense essential oil bull; Rejuvenates the skin bull; Treating acne bull; Bacterial and fungal infections bull; Wounds and scars bull; Dry hair Myrrh essential oil bull; Accelerates wound healing bull; Helps athlete #39;s foot bull; Weeping eczema bull; Bedsores bull; Severely chapped and cracked skin bull; Boils bull; Carbuncles bull; Acne and other skin ailments ...From:Alger JamesViews:0 0ratingsTime:00:40More inHowto Style

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Atopic Dermatitis – Wiki Article – Video

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Atopic Dermatitis - Wiki Article
Atopic dermatitis (AD, a type of eczema) is an inflammatory, chronically relapsing, non-contagious and pruritic (that is, itchy) skin disorder. It has been given names like "prurigo Besnier," "neurod... Atopic Dermatitis - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: James Heilman, MD Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 )From:WikiPlaysViews:0 0ratingsTime:26:45More inEducation

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Dyshidrosis – Wiki Article – Video

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Dyshidrosis - Wiki Article
Dyshidrosis (also known as "acute vesiculobullous hand eczema," "cheiropompholyx," "dyshidrotic eczema," "pompholyx," and "podopompholyx") is a skin condition that is characterized by small blisters ... Dyshidrosis - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: seav Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: Unknown Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: La belle morte Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: La belle morte Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 ) Author: kilbad Image URL: en.wikipedia.org ( Creative Commons ASA 3.0 )From:WikiPlaysViews:0 0ratingsTime:09:23More inEducation

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Probiotics may ease eczema for children: RCT data

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Daily supplements of the probioticLactobacillus plantarumCJLP133 may improve eczema in children, says a new study from South Korea.

The benefits were only observed during the supplementation period, and the probiotic did not persist in the gut after supplements were stopped, according to results published in Pediatric Allergy and Immunology .

Levels of white blood cells called eosinophils that control the mechanisms of allergy significantly decreased in children receiving the probiotic, compared with the placebo group, report researchers from Sungkyunkwan University School of Medicine, Samsung Medical Center, CJ Foods R & D Center, and Chung-Ang University College of Medicine.

Levels of the allergy marker interleukin-4 (IL-4) were also reduced in the probiotic group.

While the probiotic was associated with improvements in symptoms of eczema, the researchers caution that the long-term effects of the probiotic strain remain because it does not persist in the gut.

Probiotics for AD

Eczema, also known as atopic dermatitis, is one of the first signs of allergy during the early days of life and is said to be due to delayed development of the immune system. It is a common inflammatory skin disorder, which occurs in early childhood and may persists into adult life. According to the American Academy of Dermatologists it affects between 10 to 20% of all infants, but almost half of these kids will 'grow out' of eczema between the ages of five and 15.

Current treatments focus on alleviating symptoms, but probiotics have been studied for over 20 years for their therapeutic benefits for the condition, with numerous studies identifying significant strain-specific benefits.

Study details

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