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Daily Archives: October 17, 2012
Free speech: what it means
Posted: October 17, 2012 at 11:17 pm
Congress shall make no law respecting an establishment of religion, or prohibiting the freeexercise thereof; or abridging the freedom of speech, or of the press; or the right of thepeople peaceably to assemble, and to petition the Government for a redress of grievances.
First Amendment to the United States Constitution
From the pages rolling off our printing presses in downtown Winona, this newspaper is the First Amendment in action.
We tell you the news, our focus often on local government.
We invite you to assemble by printing your own calls for action.
We post religious gatherings, from churches that planted stones more than 150 years ago to the newest places to worship in new ways.
We celebrate your stories on these pages. You offer your opinions, your convictions, and your intimate knowledge of our region.
Together we share this mission: creating a narrative without a reaching arm of government that censors, one that limits the dialogue fundamental to democracy.
As a newspaper, we take this job very seriously.
Next week is Free Speech Week, a time to reflect on what the First Amendment really means. In the coming editions, the Winona Post will explore the rights granted by the First Amendment with an emphasis on freedom of speech and freedom of the press. First in the series is a look at the role of newspapers in both defining, and continually upholding, the right to free speech in America.
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Free speech: what it means
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Reddit Defines What Free Speech Means on Reddit
Posted: at 11:17 pm
Reddit leadership has clarified the official rules when it comes to creeps-on-Reddit, standing up for free speech on the site, said CEO Yishan Wong in a leaked memo via Gawker's Adrian Chen. "We stand for free speech," wrote Wong. "This means we are not going to ban distasteful subreddits. We will not ban legal content even if we find it odious or if we personally condemn it," he said, alluding to the recent uproar over Creep Shots and the various spin-offs that act as forums for photos of unsuspecting women in tight or revealing clothing. The site still can't get away from contradictions, however, as that "free speech" still does not include "doxxing posts," meaning anything attempting to reveal personal information, "because it incites violence and harassment against specific individuals." Or posts that link to sites that do that, like Predditors.
RELATED: Reddit Is Taking Down Its Creeps
As for elsewhere, however, Reddit admitted that it can't control the type of information the rest of the Internet circulates, as it tried to do by banning links to the entire Gawker Media network, Predditors, and anything that linked to Predditors. "We will not ban things which are legitimate investigative journalism," Wong continued. "Free speech is expressed most powerful through the press, and many times throughout history a bad actor has been exposed by an enterprising (even muckraking) journalist, and it has been to the benefit of society," he continued. Reddit had banned Chen's article about Violentacrez, the man behind a lot of the not safe for work content on the site. But Wong has since recognized that is inconsistent with their free speech mantra: "We chose to recognize that opponents have the right to criticize us, to expose us, to tell a story about useven if we don't like that story or we feel it's wrong. So we reversed the site-level ban on Chen's Gawker piece." Plus, it's not really sustainable to ban all posts that link to things which Reddit doesn't approve.
RELATED: The Internet War Over Creeps on Reddit
We'd say this is a compromise, at best, for creeps on Reddit. Sure, they get to post all the photos of women's cleavage they want. But they still have the rest of the Internet to answer to. If a website like Jezebel, for example, writes about Predditors, Reddit won't take it down. And, of course, the rest of the Internet doesn't have to play by the site's pseudo free speech rules.
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Reddit Defines What Free Speech Means on Reddit
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Tiny Satellites Launch From Space Station (Photos)
Posted: at 12:22 pm
Japan Aerospace Exploration Agency astronaut Aki Hoshide
Japan Aerospace Exploration Agency astronaut Aki Hoshide, Expedition 33 flight engineer, works near the airlock in the Kibo laboratory of the International Space Station. The Small Satellite Orbital Deployer (SSOD) previously installed on the Multi-Purpose Experiment Platform (MPEP) is visible in the airlock. This image was released Oct. 4, 2012.
Several tiny satellites float in front of the ISS in this image by an Expedition 33 crew member from the International Space Station. This image was taken Oct.4, 2012.
The satellites were released outside the Kibo laboratory using a Small Satellite Orbital Deployer attached to the Japanese module's robotic arm on Oct. 4, 2012. Japan Aerospace Exploration Agency astronaut Aki Hoshide, flight engineer, set up the satellite deployment gear inside the lab and placed it in the Kibo airlock.
Several tiny satellites float in front of the ISS in this image by an Expedition 33 crew member from the International Space Station. This image was taken Oct.4, 2012.
Several tiny satellites are featured in this image photographed by an Expedition 33 crew member on the International Space Station. The satellites were released outside the Kibo laboratory using a Small Satellite Orbital Deployer attached to the Japanese module's robotic arm on Oct. 4, 2012.
Small Satellite Orbital Deployer (SSOD) attached to the Japanese module's robotic arm is featured in this image photographed by an Expedition 33 crew member on the International Space Station. Several tiny satellites were released outside the Kibo laboratory using the SSOD on Oct. 4, 2012.
The satellites were released outside the Kibo laboratory using a Small Satellite Orbital Deployer attached to the Japanese module's robotic arm on Oct. 4, 2012.
Several tiny satellites are featured in this image photographed by an Expedition 33 crew member on the International Space Station on Oct. 4, 2012.
The Cubesat mission expands and introduces new utilization of the JEM using JEMRMS and JEM AL, which are unique features of the JEM module. The main purpose of this mission is to establish processes and procedures for satellite verifications, integration of the satellites, launching satellites to ISS, and deploying satellites into the space.
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Tiny Satellites Launch From Space Station (Photos)
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Space station investigation to test fresh food experience
Posted: at 12:22 pm
ScienceDaily (Oct. 16, 2012) With all the prepackaged gardening kits on the market, an exceptionally green thumb isn't necessary to grow your own tasty fresh vegetables here on Earth. The same may hold true for U.S. astronauts living and working aboard the International Space Station when they receive a newly developed Vegetable Production System, called VEGGIE for short, set to launch aboard SpaceX's Dragon capsule on NASA's third Commercial Resupply Services mission next year.
"Our hope is that even though VEGGIE is not a highly complex plant growth apparatus, it will allow the crew to rapidly grow vegetables using a fairly simple nutrient and water delivery approach," said Howard Levine, Ph.D. and chief scientist, NASA's Kennedy Space Center International Space Station Research Office.
Gioia Massa, a postdoctoral fellow in the Surface Systems Group of Kennedy's Engineering Directorate, has been working with the International Space Station Research Office to validate the VEGGIE hardware here on Earth before it takes flight next year.
"VEGGIE could be used to produce faster-growing species of plants, such as lettuce or radishes, bok choy or Chinese cabbage, or even bitter leafy greens" Massa said. "Crops like tomatoes, peas or beans in which you'd have to have a flower and set fruit would take a little longer than a 28-day cycle."
It may not sound like a big deal to us Earthlings who can just run out to our local produce stand or supermarket when we have a hankering for a salad, but when you're living 200 miles above the surface of the planet, truly fresh food only comes a few times a year.
"When the resupply ships get up there, the fresh produce gets eaten almost immediately," Massa said.
Weighing in at about 15 pounds and taking up the space of a stove-top microwave oven, the stowable and deployable VEGGIE system was built by Orbital Technologies Corporation, or ORBITEC, in Madison, Wis. The company designed the system to enable low-maintenance experiments, giving astronauts the opportunity to garden recreationally.
"Based upon anecdotal evidence, crews report that having plants around was very comforting and helped them feel less out of touch with Earth," Massa said. "You could also think of plants as pets. The crew just likes to nurture them."
In simple terms, the VEGGIE system works like this: Clear Teflon bellows that can be adjusted for plants as they grow are attached to a metal frame housing the system's power and light switches. A rooting pillow made of Teflon-coated Kevlar and Nomex will contain the planting media, such as soil or claylike particles, along with fertilizer pellets. Seeds either will be preloaded in the pillows on Earth or inserted by astronauts in space. To water the plants, crew members will use a reservoir located beneath the pillows and a root mat to effectively add moisture through an automatic wicking process.
VEGGIE is set to join other plant growth facilities that vary in size and complexity, such as the Lada greenhouse unit and the ABRS, short for Advanced Biological Research System. VEGGIE is the simplest of the three designs, but has the largest surface area for planting and is expected to produce data on a more regular basis. Levine noted that the ability to grow plants in microgravity has really evolved throughout the past decade.
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Space station investigation to test fresh food experience
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Space Station Opens Launch Pad for Tiny Satellites
Posted: at 12:22 pm
Astronauts on the International Space Station have transformed their high-flying laboratory into a new kind of launch pad for tiny satellites in a bid to boost student interest and access to space.
This month, the space station's Expedition 33 crew launched five tiny Cubesats, each only a few inches wide, using a small satellite orbital deployer from Japan's space agency JAXA. They were the first Cubesat satellites ever launched from the International Space Station, coming 2 1/2 years after NASA announced the CubeSat program.
"This was a learning experience for everyone," said Andres Martinez, the NASA Ames project manager for one of the satellites.
The cubesats were launched from the station's Japanese Kibo laboratory on Oct. 4, which also marked the 55th anniversary of the world's first satellite launch in 1957 that placed Russia's Sputnik 1 in orbit and ushered in the Space Age. [Photos: Tiny Satellites Launch from Space Station]
"Fifty-five years ago we launched the first satellite from Earth. Today we launched them from a spacecraft," space station commander Sunita Williams of NASA said on launch day to mark the moment. "Fifty years from now, I wonder where we'll be launching them from."
The JAXA satellite-deploying device arrived at the station aboard a Japanese cargo ship in July. Japanese astronaut Akihiko Hoshide placed the deployer, which is about the size of a small rabbit cage, into a small airlock in the Kibo lab. Then, the astronaut sealed the airlock, opened it up to space, and commanded the station's Kibo robotic armto pick up the deployer and bring it outside for satellite deployment.
All told, the procedure took only four hours of astronaut time with no spacewalk required.
"If you can imagine, deploying satellites from station can be quite risky," Martinez said. "We were going through that whole experience of conducting analysis to ensure this would be something safe to do from station, not only from the point of deployment but also taking up the satellites inside station."
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Space Station Opens Launch Pad for Tiny Satellites
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Producers embrace sheep DNA testing
Posted: at 12:22 pm
AUSTRALIA'S sheep producers are queuing up to adopt new DNA technology, with the latest Sheep Genomics Pilot Project fully subscribed.
The DNA testing program, conducted by the Co-operative Research Centre for Sheep Industry Innovation (Sheep CRC), was booked out within days of its opening in August.
The Genomics Pilot Project offers three DNA testing programs: a SNP test for parentage at $17/test; a SNP test for Merino poll/horn for $17/test; and the 50k SNP test for prediction of genomic breeding values for sires at a cost of $50/test. Merinos tested for parentage, or with the 50k SNP, are receiving the poll test results at no additional cost.
The 1500 genotyping tests available as part of Pilot Project III have been fully subscribed, and a further 1500 tests allocated for commercial scale trials has also been over-subscribed, Sheep CRC chief executive James Rowe said.
With the use of DNA analysis and genomic breeding values being a very new technology, R&D is occurring in parallel with the Genomics Pilot Projects in order to define the most effective use of the new technologies in practical breeding programs.
"For this reason, the CRCs genetics research team will be working closely with a group of nine commercial-scale breeders who have submitted expressions of interest.
This is a resounding vote of confidence in the commercial value of genomics technology for sheep breeding programs.
The Sheep CRC has conducted a Genomics Pilot Project yearly since 2010, with the number of rams tested each year increasing dramatically, from approximately 450 rams in 2010, to 860 rams in 2011 and now 3000 rams in 2012.
This years project will build on the earlier trials, which provided genomic predictions for new traits including dressing percentage and lean meat yield, together with traits for meat eating quality such as intramuscular fat and shear force that are difficult and expensive to measure.
It is expected that the accuracy levels of research breeding values (RBVs) and Australian Sheep Breeding Values (ASBVs) will further improve as a result of the additional data collected during the Genomics Pilot Project and through the Information Nucleus program.
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Producers embrace sheep DNA testing
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DNA evidence could free the innocent-if it were available
Posted: at 12:22 pm
By: Jessica Zafra October 17, 2012 3:59 PM
InterAksyon.com The online news portal of TV5
After I saw "Give Up Tomorrow," the documentary on the apparently wrongful arrest, trial, and conviction of Paco Larraaga, I wondered how many innocent persons have been doomed to rot in our overcrowded jails. Thats how I heard about the Innocence Project Philippines, a network of law schools, non-governmental organizations and academic laboratories that seeks to make justice accessible for wrongfully convicted persons. Founded in 2012, the Innocence Project is presently headquartered at the DNA Analysis Laboratory at the University of the Philippines in Diliman.
Being a compulsive viewer of the Law and Order shows and forensic dramas on TV, I asked for an interview with the head of the UP DNA Analysis Laboratory, Dr. Maria Corazon de Ungria. Unfortunately she didnt have the time, but she did answer, via email, my very elementary questions about the initiative. An NAST Outstanding Young Scientist Awardee in 2003, De Ungria is also the director of the Program on Forensic and Ethnicity of the Philippine Genome Center. She gave technical assistance in the formulation of the Rules on DNA Evidence, and has been an expert witness in criminal cases.
Incidentally, in a newspaper article she published two weeks ago, De Ungria noted that Eyewitness testimony is recognized to be the leading cause of judicial errors in the US and elsewhere. After I wrote about the Larraaga case I heard from various people who saw the accused in Manila on the day he was supposed to be committing the crimes in Cebu. As the movie points out, the Larraaga case is notable for the number of eyewitnesses whose testimony was ignored.
Have you any idea as to the number of wrongful convictions in the Philippines?
I dont think there is an estimate of the overall number of wrongful convictions. In 2004, in the case People of the Philippines v Mateo, the Supreme Court reported about 71.8% of all death penalty cases that were reviewed resulted in a modification of the sentence, a remanding of the case back to the lower courts and in some, acquittal of the accused.
Statistics would disclose that within the eleven-year period since the re-imposition of the death penalty law in 1993 until June 2004, the cases where the judgment of death has either been modified or vacated consisted of an astounding 71.77 percent of the total of death penalty cases directly elevated before the Court on automatic review that translates to a total of 651 out of 907 appellants saved from lethal injection.
What is the process for getting a conviction reviewed with your help? How has the Innocent Project been received by the Philippine police and judiciary?
The project is just about to start. We are in the process of registering the group with the SEC and launching the project. The target date and sites for the launch is December 9, 2012 at the National Bilibid Prison in the morning and the Correctional Institute of Women in the afternoon. We are still processing the papers and request forms but we are hoping to make this happen soon. Since the project is really based on the passionate commitment of volunteers and students who want to make a difference, we are actually needing financial assistance for the launch. So best to check the Facebook account for further information.
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DNA evidence could free the innocent-if it were available
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Top Ten Companies in DNA Sequencing
Posted: at 12:21 pm
NEW YORK, Oct. 17, 2012 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:
Top Ten Companies in DNA Sequencing
INTRODUCTION
The story of molecular biology is being both written and printed by sequencing toolsvarious chapters being currently authored by oncologists, ID experts, pathologists, and so forth. The narrative is understood by only those select few who have the cross discipline knowledge to comprehend what the sequencing tools output, and who also have the niche domain experience to act upon knowledge of that data. Recently, this story has begun to change as low cost next generation sequencing democratizes genome data, allowing a politics and commerce of inclusion, to enter the lab and now also the clinic.
Diagnostic manufacturers can now afford to develop sequencing tools as diagnostic shortcuts. The clinician does not need to understand the mathematical underpinnings of 16SrRNA coverage for phylogeny to run a rapid anthrax test.
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Top Ten Companies in DNA Sequencing
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"Seventy-two Is the New 30": Why Are We Living So Much Longer?
Posted: at 12:21 pm
Charles Q. Choi
The death rate in industrialized countries has dropped so much in the last century or so that, for example, a 72-year-old in Japan has the same chances of dying as a preindustrial 30-year-old did, or does, a new study says.
"In other words," the researchers write, " ... 72 is the new 30."
Humans nowadays survive much longer than our closest living relatives, chimpanzees, which rarely live past 50. Even hunter-gathererswho often lack the advanced nutrition, modern medicine, and other benefits of industrialized livinghave twice the life expectancy at birth as wild chimpanzees.
So what's changed in us since the days of our ape ancestors? Are we living so much longer mainly because of changes in our lifestyles or because of genetic mutationsin other words, evolution?
(Related: "Longevity Genes Found; Predict Chances of Reaching a Hundred.")
To find out how we got to this advanced state, the study team compared death rates in industrialized countries with those in modern-day hunter-gatherer groups, whose lifestyles more closely mirror those of early modern humans.
The researchers found that the mortality rate at younger agesduring the first couple decades of lifein the industrialized world is now about 200 times lower overall than in today's hunter-gatherer groups.
"We have a greater distance in mortality levels between today's lowest-mortality nations and hunter-gatherers than there is between hunter-gatherers and chimpanzees," said study leader Oskar Burger, an evolutionary anthropologist at the Max Planck Institute for Demographic Research in Germany.
Longevity's Great Leap Forward
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"Seventy-two Is the New 30": Why Are We Living So Much Longer?
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Idera Pharma: Itching For Touch Up…
Posted: at 12:21 pm
10/17/2012 6:08 AM ET Psoriasis, a chronic inflammatory skin disease, is said to be probably one of the oldest known diseases. It is estimated that as many as 7.5 million Americans and 125 million people worldwide have psoriasis. Though there are several different types of psoriasis, the most prevalent form of the disease is plaque psoriasis.
The truth about psoriasis is that it is not just a cosmetic problem as this devastating disease causes physical pain as well as frustration and self-consciousness to the patients. There is no cure yet for psoriasis, but a number of treatments are available to manage its symptoms.
Working on the development of a treatment for patients with moderate to severe plaque psoriasis is Idera Pharmaceuticals Inc. (IDRA: Quote), a clinical stage biotechnology company.
For readers who are new to Idera, here's a brief overview of its pipeline and the upcoming events to watch out for...
The most-advanced compound in the company's pipeline is IMO-3100, which is under phase II testing in patients with moderate to severe plaque psoriasis. The phase II trial of IMO-3100 for psoriasis was initiated in April of this year and it completed the enrollment of 44 patients this month. Idera expects reporting top-line data from this phase II study by year-end 2012.
The clinical activity of IMO-3100, including the impact on Psoriasis Area Severity Index (PASI), mean focal psoriasis severity, and Physician Global Assessment (PGA) scores are being assessed in the phase II study. In addition, biopsies of psoriasis plaques are evaluated for treatment-related changes in epidermal thickness and immune cell infiltrates consistent with the intended mechanism of action, according to the company.
The completion of the phase II study for IMO-3100 in psoriasis is expected during the first half of 2013.
Amgen's Enbrel, Abbott Labs' Humira, and Johnson & Johnson's Remicade, Simponi and Stelara are some of the FDA-approved biologic drugs for psoriasis. The global psoriasis market is estimated to be worth around $4.5 billion to $5 billion.
Idera's psoriasis drug candidate - IMO-3100, is a dual antagonist of Toll-like receptor TLR7 and TLR9, which play a key role in inflammation and immunity.
Next in the company's pipeline is IMO-8400, a first-in-class antagonist of TLRs 7, 8, and 9, for the treatment of lupus. Given the fact that IMO-8400 has demonstrated preclinical efficacy - in mouse models of lupus, Idera anticipates initiating a phase I dose escalation trial during the fourth quarter of 2012 to evaluate the safety and pharmacodynamics of IMO-8400 in healthy subjects.
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Idera Pharma: Itching For Touch Up...
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