Biology for the post-genomic era <\/p>\n
Fully Open Access. Genome Biology covers all areas of biology and biomedicine studied from a genomic and post-genomic perspective. Content includes research, new methods and software tools, and reviews, opinions and commentaries. Areas covered include, but are not limited to: sequence analysis; bioinformatics; insights into molecular, cellular and organismal biology; functional genomics; epigenomics; population genomics; proteomics; comparative biology and evolution; systems and network biology; genomics of disease; and clinical genomics. All content is open access immediately on publication. <\/p>\n
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Enter exitrons <\/p>\n
Dorothee Staiger and Gordon Simpson discuss the discovery of exon-like introns and their contributions to proteome complexity and phenotypic diversity <\/p>\n
Focus on splicing <\/p>\n
Chris Burge and Daniel Dominguez discuss how splicing-regulatory proteins modulate assembly of the spliceosome to activate and repress splicing <\/p>\n
Diagnosing Mendelian diseases <\/p>\n
Advantages over clinical exome sequencing can be achieved by using an NGS-based multiplexing assay involving comprehensive gene panels. <\/p>\n
Read length cost-benefit <\/p>\n
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