Persons with ankylosing spondylitis (AS)with or without psoriasishave different demographic, genetic, radiographic, and clinical variables from persons with axial psoriatic arthritis (axPsA), according to results of a new study. The findings suggest that axPsA is a distinct entity.<\/p>\n
The researchers compared data of patients with AS with psoriasis (n=91) and patients with AS without psoriasis (n=675) with data of patients with axPsA (n=477) and patients with peripheral PsA (n=826).<\/p>\n
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All patients cases were followed prospectively using the same protocol. A logistic regression analysis was performed and adjusted for follow-up duration.<\/p>\n
Results showed that patients with AS with or without psoriasis were younger, were more often male, were positive for HLA-B*27 antigen, had received more treatment with biologics, and had a higher grade of sacroiliitis.<\/p>\n
Additionally, patients with AS had more back pain at presentation, worse Bath Ankylosing Spondylitis Disease Activity Index and Bath Ankylosing Spondylitis Metrology Index scores, and worse physician global assessments.<\/p>\n
Similar differences were detected when patients with AS and psoriasis were compared with those with axPsA, and in a regression model.<\/p>\n
Melinda Stevens<\/p>\n
Reference:<\/p>\n
Feld J, Ye JY, Chandran V, et al. Is axial psoriatic arthritis distinct from ankylosing spondylitis with and without concomitant psoriasis? [published online October 8, 2019]. Rheumatology. doi:10.1093\/rheumatology\/kez457.<\/p>\n<\/p>\n
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View post: Persons with ankylosing spondylitis (AS)with or without psoriasishave different demographic, genetic, radiographic, and clinical variables from persons with axial psoriatic arthritis (axPsA), according to results of a new study. The findings suggest that axPsA is a distinct entity. The researchers compared data of patients with AS with psoriasis (n=91) and patients with AS without psoriasis (n=675) with data of patients with axPsA (n=477) and patients with peripheral PsA (n=826). Continue reading
\nResearchers Identify Differences Between Axial Psoriatic Arthritis and Ankylosing Spondylitis - Consultant360<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"