{"id":189159,"date":"2017-04-23T01:04:09","date_gmt":"2017-04-23T05:04:09","guid":{"rendered":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/lsd-as-therapy-how-scientists-are-reclaiming-psychedelics-hack-abc-online\/"},"modified":"2017-04-23T01:04:09","modified_gmt":"2017-04-23T05:04:09","slug":"lsd-as-therapy-how-scientists-are-reclaiming-psychedelics-hack-abc-online","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/psychedelics\/lsd-as-therapy-how-scientists-are-reclaiming-psychedelics-hack-abc-online\/","title":{"rendered":"LSD as therapy: How scientists are reclaiming psychedelics &#8211; Hack &#8230; &#8211; ABC Online"},"content":{"rendered":"<p><p>    At 6.30am on Thursday 29 October 2009, Friederike Meckel    Fischers doorbell rang. There were ten policemen outside. They    searched the house, put handcuffs on Friederike  a diminutive    woman in her 60s  and her husband, and took them to a remand    prison. The couple had their photographs and fingerprints taken    and were put in separate cells in isolation. After a few hours,    Friederike, a psychotherapist, was taken for questioning.  <\/p>\n<p>    The officer read back to her the promise of secrecy she had    each client make at the start of her group therapy sessions.    Then I knew I was really in trouble, she says.  <\/p>\n<p>      I promise not to divulge the location or names of the people      present or the medication. I promise not to harm myself or      others in any way during or after this experience. I promise      that I will come out of this experience healthier and wiser.      I take personal responsibility for what I do here.    <\/p>\n<p>    The Swiss police had been tipped off by a former client whose    husband had left her after they had attended therapy. She held    Friederike responsible.  <\/p>\n<p>    What got Friederike in trouble were her unorthodox therapy    methods. Alongside separate sessions of conventional talk    therapy, she offered a catalyst, a tool to help her clients    reconnect with their feelings, with people around them, and    with difficult experiences in their lives. That catalyst was    LSD. In many of her sessions, they would also use another    substance: MDMA, or ecstasy.  <\/p>\n<p>    Friederike was accused of putting her clients in danger,    dealing drugs for profit, and endangering society with    intrinsically dangerous drugs. Such psychedelic therapy is on    the fringes of both psychiatry and society. Yet LSD and MDMA    began life as medicines for therapy, and new trials are testing    whether they could be again.  <\/p>\n<p>    In 1943, Albert Hofmann, a chemist at the Sandoz pharmaceutical    laboratory in Basel, Switzerland, was trying to develop drugs    to constrict blood vessels when he accidentally ingested a    small quantity of lysergic acid diethylamide, LSD. The effects    shook him. As he writes in his book LSD, My Problem Child:  <\/p>\n<p>    Objects as well as the shape of my associates in the    laboratory appeared to undergo optical changes Light was so    intense as to be unpleasant. I drew the curtains and    immediately fell into a peculiar state of drunkenness,    characterised by an exaggerated imagination. With my eyes    closed, fantastic pictures of extraordinary plasticity and    intensive colour seemed to surge towards me. After two hours,    this state gradually subsided and I was able to eat dinner with    a good appetite.  <\/p>\n<p>    Intrigued, he decided to take the drug a second time in the    presence of colleagues, an experiment to determine whether it    was indeed the cause. The faces of his colleagues soon appeared    like grotesque coloured masks, he writes:  <\/p>\n<p>    I lost all control of time: space and time became more and    more disorganised and I was overcome with fears that I was    going crazy. The worst part of it was that I was clearly aware    of my condition though I was incapable of stopping it.  <\/p>\n<p>      Occasionally I felt as being outside my body. I thought I had      died. My ego was suspended somewhere in space and I saw my      body lying dead on the sofa.    <\/p>\n<p>    \"I observed and registered clearly that my alter ego was    moving around the room, moaning.  <\/p>\n<p>    But he seemed particularly struck by what he felt the next    morning: Breakfast tasted delicious and was an extraordinary    pleasure. When I later walked out into the garden, in which the    sun shone now after a spring rain, everything glistened and    sparkled in a fresh light. The world was as if newly created.    All my senses vibrated in a condition of highest sensitivity    that persisted for the entire day.  <\/p>\n<p>    Hofmann felt it was of great significance that he could    remember the experience in detail. He believed the drug could    hold tremendous value to psychiatry. The Sandoz labs, after    ensuring it was non-toxic to rats, mice and humans, soon    started offering it for scientific and medical use.  <\/p>\n<p>    One of the first to start using the drug was Ronald Sandison.    The British psychiatrist visited Sandoz in 1952 and, impressed    by Hofmanns research, left with 100 vials of what was by then    called Delysid. Sandison immediately began giving it to    patients at Powick Hospital in Worcestershire who were failing    to make progress in traditional psychotherapy. After three    years, the hospital bosses were so pleased with the results    that they built a new LSD clinic. Patients would arrive in the    morning, take their LSD, then lie down in private rooms. Each    had a record player and a blackboard for drawing on, and nurses    or registrars would check on them regularly. At 4pm the    patients would convene and discuss their experiences, then a    driver would take them home, sometimes while they were still    under the influence of the drug.  <\/p>\n<p>    Around the same time, another British psychiatrist, Humphry    Osmond, working in Canada, experimented with using LSD to help    alcoholics stop drinking. He reported that the drug, in    combination with supportive psychiatry, achieved abstinence    rates of 4045 per cent  far higher than any other treatment    at the time or since. Elsewhere, studies of people with    terminal cancer showed that LSD therapy could relieve severe    pain, improve quality of life and alleviate the fear of death.  <\/p>\n<p>    In the USA, the CIA tried giving LSD to unsuspecting members of    the public to see if it would make them give up secrets.    Meanwhile at Harvard University, Timothy Leary  encouraged by,    among others, the beat poet Allen Ginsberg  gave it to artists    and writers, who would then describe their experiences. When    rumours spread that he was giving drugs to students,    law-enforcement officials started investigating and the    university warned students against taking the drug. Leary took    the opportunity to preach about the drugs power as an aid to    spiritual development, and was soon sacked from Harvard, which    further fuelled his and the drugs notoriety. The scandal had    caught the eye of the press and soon the whole country had    heard of LSD.  <\/p>\n<p>    By 1962, Sandoz was cutting back on its distribution of LSD,    the result of restrictions on experimental drug use brought on    by an altogether different drug scandal: birth defects linked    to the morning-sickness drug thalidomide. Paradoxically, the    restrictions coincided with an increase in LSDs availability     the formula was not difficult or expensive to obtain, and those    who were determined to could synthesise it with moderate    difficulty and in great amounts.  <\/p>\n<p>    Still, moral panic about its effects on young minds was rife.    The authorities were also worried about LSDs association with    the counterculture movement and the spread of    anti-authoritarian views. Calls for a nationwide ban soon    followed, and many psychiatrists stopped using LSD as its    negative reputation grew.  <\/p>\n<p>    One of many stories in the press told of Stephen Kessler, who    murdered his mother-in-law and claimed afterwards that he    didnt remember what hed done as he was flying on LSD. In    the trial, it emerged that he had taken LSD a month earlier,    and at the time of the murder was intoxicated only with alcohol    and sleeping pills, but millions believed that LSD had turned    him into a killer. Another report told of college students who    went blind after staring at the sun on LSD.  <\/p>\n<p>    Two US Senate subcommittees held in 1966 heard from doctors who    claimed that LSD caused psychosis and the loss of all cultural    values, as well as from LSD supporters such as Leary and    Senator Robert Kennedy, whose wife Ethel was said to have    undergone LSD therapy. Perhaps to some extent we have lost    sight of the fact that it can be very, very helpful in our    society if used properly, said Kennedy, challenging the Food    and Drug Administration for shutting down LSD research    programmes.  <\/p>\n<p>    Possession of LSD was made illegal in the UK in 1966 and in the    USA in 1968. Experimental use by researchers was still possible    with licences, but with the stigma attached to the drugs legal    status, these became extremely hard to get. Research ground to    a halt, but illegal recreational use carried on.  <\/p>\n<p>    At the age of 40, after 21 years of marriage, Friederike Meckel    Fischer fell in love with another man. Sadly, as she soon    discovered, he was using her to get out of his own marriage. I    had a pain within myself with this man having left me, with my    husband whom I couldnt connect to, she says. It was just    like I was out of myself.  <\/p>\n<p>    Her solution was to become a psychotherapist. She says she    never thought of going into therapy herself, which in 1980s    West Germany was reserved for only the most serious conditions.    Besides which, her upbringing taught her to do things herself    rather than seek help from others.  <\/p>\n<p>    Friederike was at the time working as an occupational    physician. She recognised that many of the problems she saw in    her patients were rooted in problems with their bosses,    colleagues or families. I came to the conclusion that    everything they were having trouble with was connected to    relationship issues, she says.  <\/p>\n<p>    A former professor of hers recommended she try a technique    called holotropic breathwork. Developed by Stanislav Grof, one    of the pioneers of LSD psychotherapy, this is a way to induce    altered states of consciousness through accelerated and deeper    breathing, like hyperventilation. Grof had developed holotropic    breathwork in response to bans on LSD use around the world.  <\/p>\n<p>    Over three years, travelling back and forth to the USA on    holidays, Friederike underwent training with Grof as a    holotropic breathwork facilitator. At the end of it, Grof    encouraged her to try psychedelics.  <\/p>\n<p>    In the last seminar, a colleague gave her two little blue pills    as a gift. When she got back to Germany, Friederike shared one    of the blue pills with her friend Konrad, who later became her    husband. She says she felt herself lifted by a wave and thrown    onto a white beach, able to access parts of her psyche that    were off-limits before. The first experience was breathtaking    for me, she says. I only thought: Thats it. I can see    things. And I started feeling. That was, for me,    unbelievable.  <\/p>\n<p>    The pills were MDMA, a drug which had entered the spotlight in    1976 when American chemist Alexander Sasha Shulgin    rediscovered it 62 years after it was patented by Merck and    then forgotten. In a story echoing that of LSDs origins, upon    taking it, Shulgin noted feelings of pure euphoria and solid    inner strength, and felt he could talk about deep or personal    subjects with special clarity. He introduced it to his friend    Leo Zeff, a retired psychotherapist who had worked with LSD and    believed the obligation to help patients took priority over the    law. Zeff had continued to work with LSD secretly after its    prohibition. MDMAs potential brought Zeff out of retirement.    He travelled around the USA and Europe to instruct therapists    on MDMA therapy. He called it Adam because it put the patient    in a primordial state of innocence, but at the same time, it    had acquired another name in nightclubs: ecstasy.  <\/p>\n<p>    MDMA was made illegal in the UK by a 1977 ruling that put the    entire chemical family in the most tightly controlled category:    class A. In the USA, the Drug Enforcement Administration (DEA),    set up by Richard Nixon in 1973, declared a temporary ban in    1985. At a hearing to decide its permanent status, the judge    recommended that it should be placed in schedule three, which    would allow use by therapists. But the DEA overruled the    judges decision and put MDMA in schedule one, the most    restrictive category. Under American influence, the UN    Commission on Narcotic Drugs gave MDMA a similar classification    under international law (though an expert committee formed by    the World Health Organization argued that such severe    restrictions were not warranted).  <\/p>\n<p>    Schedule one substances are permitted to be used in research    under the UN Convention on Psychotropic Substances. In Britain    and the USA, researchers and their institutions must apply for    special licences, but these are expensive to obtain, and    finding manufacturers who will supply controlled drugs is    difficult.  <\/p>\n<p>    But in Switzerland, which at the time was not a signatory to    the convention, a small group of psychiatrists persuaded the    government to permit the use of LSD and MDMA in therapy. From    1985 until the mid-1990s, licensed therapists were permitted to    give the drugs to any patients, to train other therapists in    using the drugs, and to take them themselves, with little    oversight.  <\/p>\n<p>    Believing that MDMA might help her gain a deeper understanding    of her own problems, Friederike applied for a place on a    psycholytic therapy course in Switzerland. In 1992, she and    Konrad were accepted into a training group run by a licensed    therapist named Samuel Widmer.  <\/p>\n<p>    The course took place on weekends every three months at    Widmers house in Solothurn, a town west of Zurich. Central to    the training was taking the substances a number of times, 12    altogether, to get to know their effects and go through a    process of self-exploration. Friederike says the drug    experiences showed her how her whole life had been coloured by    the loss of her father at the age of 5 and the hardship of    growing up in postwar West Germany.  <\/p>\n<p>    I can detect relations, interconnections between things that I    couldnt see before, she says of her experiences with MDMA.  <\/p>\n<p>      I could look at difficult experiences in my life without      getting right away thrown into them again. I could for      example see a traumatic experience but not connect to the      horrible feeling of the moment.    <\/p>\n<p>    \"I knew it was a horrible thing, and I could feel that I have    had fear but I didnt feel the fear.  <\/p>\n<p>    People on psychedelic highs often speak of profound, spiritual    experiences. Back in the 1960s, Walter Pahnke, a student of    Timothy Leary, conducted a notorious experiment at Boston    Universitys Marsh Chapel showing that psychedelics could    induce these.  <\/p>\n<p>    He gave ten volunteers a large dose of psilocybin  the active    ingredient in magic mushrooms  and ten an active placebo,    nicotinic acid, which caused a tingling sensation but no mental    effects. Eight of the psilocybin group had spiritual    experiences, compared with one of the placebo group. In later    studies, researchers have identified core characteristics of    such experiences, including ineffability, the inability to put    it into words; paradoxicality, the belief that contradictory    things are true at the same time; and feeling more connected to    other people or things.  <\/p>\n<p>    When the experience can be really useful is when they feel a    connection even with someone who has caused them hurt, and an    understanding of what may have caused them to behave in the way    they did, says Robin Carhart-Harris, a psychedelics researcher    at Imperial College London. I think the power to achieve those    kinds of realisations really speaks to the incredible value of    psychedelics and captures why they can be so effective and    valuable in therapy. I think that can only really happen when    defences dissolve away. Defences get in the way of those    realisations.  <\/p>\n<p>    He compares the feeling of connection with things beyond    oneself to the overview effect felt by astronauts when they    look back on the Earth. All of a sudden they think, How silly    of me and people in general to have conflict and silly little    hang-ups that we think are massive and important. When youre    up in space looking down on the entirety of the Earth, it puts    it into perspective. I think a similar kind of overview is    engendered by psychedelics.  <\/p>\n<p>    Carhart-Harris is conducting the first clinical trial to study    psilocybin as a treatment for depression. He is one of a few    researchers across the world who are pushing ahead with    research on psychedelic therapy. Twelve people have taken part    in his study so far.  <\/p>\n<p>    They begin with a brain scan, and a long preparation session    with the psychiatrists. On the therapy day, they arrive at 9am,    complete a questionnaire, and have tests to make sure they    havent taken other drugs. The therapy room has been decorated    with drapes, ornaments, coloured glowing lights, electric    candles, and an aromatiser. A PhD student, who is also a    musician, has prepared a playlist, which the patient can listen    to either through headphones or from high-quality speakers in    the room. They spend most of the session lying on a bed,    exploring their thoughts. Two psychiatrists sit with them, and    interact when the patient wants to talk. The patients have two    therapy sessions: one with a low dose, then one with a high    dose. Afterwards, they have a follow-up session to help them    integrate their experiences and cultivate healthier ways of    thinking.  <\/p>\n<p>    I meet Kirk, one of the participants, two months after his    high-dose session. Kirk had been depressed, particularly since    his mothers death three years ago. He experienced entrenched    thought patterns, like going round and round on a racetrack of    negative thoughts, he says. I wasnt as motivated, I wasnt    doing as much, I wasnt exercising any more, I wasnt as    social, I was having anxiety quite a bit. It just deteriorated.    I got to the point where I felt pretty hopeless. It didnt    match really what was going on in my life. I had a lot of good    things going on in my life. Im employed, Ive got a job, Ive    got family, but really it was like a quagmire that you sink    into.  <\/p>\n<p>    At the peak of the drug experience, Kirk was deeply affected by    the music. He surrendered himself to it and felt overcome with    awe. When the music was sad, he would think of his mother, who    had been ill for many years before her death. I used to go to    the hospital and see her, and a lot of the time shed be    asleep, so I wouldnt wake her up; Id just sit on the bed. And    shed be aware I was there and wake up. It was a very loving    feeling. Quite intensely I went through that moment. I think    that was quite good in a way. I think it helped to let go.  <\/p>\n<p>    During the therapy sessions, there were moments of anxiety as    the drugs effects started to take hold, when Kirk felt cold    and became preoccupied with his breathing. But he was reassured    by the therapists, and the discomfort passed. He saw bright    colours, like being at the funfair, and felt vibrations    permeate his body. At one point, he saw the Hindu elephant god    Ganesh look in at him, as if checking on a child.  <\/p>\n<p>    Although the experience had been affecting, he noticed little    improvement in his mood in the first ten days afterwards. Then,    while out shopping with friends on a Sunday morning, he felt an    upheaval. I feel like theres space around me. It felt like    when my mum was still alive, when I first met my partner, and    everything was kind of OK, and it was so noticeable because I    hadnt had it in a while.  <\/p>\n<p>    There have been ups and downs since, but overall, he feels much    more optimistic. I havent got that negativity any more. Im    being more social; Im doing stuff. That kind of heaviness,    that suppressed feeling has gone, which is amazing, really.    Its lifted a heavy cloak off me.  <\/p>\n<p>    Another participant, Michael, had been battling depression for    30 years, and tried almost every treatment available. Before    taking part in the trial, he had practically given up hope.    Since the day of his first dose of psilocybin, he has felt    completely different. I couldnt believe how much it had    changed so quickly, he says.  <\/p>\n<p>      My approach to life, my attitude, my way of looking at the      world, just everything, within a day.    <\/p>\n<p>    One of the most valuable parts of the experience helped him to    overcome a deep-rooted fear of death. I felt like I was being    shown what happens after that, like an afterlife, he says.    Im not a religious person and Id be hard pushed to say I was    anything near spiritual either, but I felt like Id experienced    some of that, and experienced the feeling of an afterlife, like    a preview almost, and I felt totally calm, totally relaxed,    totally at peace. So that when that time comes for me, I will    have no fear of it at all.  <\/p>\n<p>    During her training with Samuel Widmer, Friederike also worked    in an addiction clinic. The insights from her drug experiences    gave her new empathy. All of a sudden I could understand my    clients in the clinic with their alcohol addiction, she says.    They were coping differently than I did. They had almost the    same problems or symptoms I had, only I hadnt started    drinking. But only a few of them were able to open up about    how those experiences made them feel. She wondered: could an    MDMA experience help them release those emotions?  <\/p>\n<p>    MDMA is a tamer relative of the classic psychedelics     psilocybin, LSD, mescaline, DMT. They have effects that can be    disturbing, like sensory distortions, the dissolution of ones    sense of self, and the vivid reliving of frightening memories.    MDMAs effects are shorter-lasting, making it easier to handle    in a psychotherapy session.  <\/p>\n<p>    Friederike opened her own private psychedelic therapy practice    in Zurich in 1997. During the next few years, she began hosting    weekend group therapy sessions with psychedelics in her home,    inviting clients who had failed to make progress in    conventional talking therapy.  <\/p>\n<p>    Since the 1950s, psychiatrists have recognised the importance    of context in determining what sort of experience the LSD taker    would have. They have emphasised the importance of set  the    users mindset, their beliefs, expectations, and experience     and setting  the physical milieu where the drug is taken,    the sounds and features of the environment and the other people    present.  <\/p>\n<p>    A supportive setting and an experienced therapist can lower the    risk of a bad trip, but frightening experiences still happen.    According to Friederike, they are part of the therapeutic    experience. If a client is able to go through or lets himself    be led through and work through, the bad trip turns into the    most important step on the way to himself, she says. But    without a correct setting, without a therapist who knows what    hes doing and without the commitment of the client, we end up    in a bad trip.  <\/p>\n<p>    Her clients would come to her house on a Friday evening, talk    about their recent issues and discuss what they wanted to    achieve in the drug session. On Saturday morning, they would    sit in a circle on mats, make the promise of secrecy, and each    take a personal dose of MDMA agreed with Friederike in advance.    Friederike would start with silence, then play music, and speak    to the clients individually or as a group to work through their    issues. Sometimes she would ask other members of the group to    assume the role of a clients family members, and have them    discuss problems in their relationship. In the afternoon they    would do the same with LSD, which would often let the    participants feel as though they were reliving traumatic    memories. Friederike would guide them through the experience,    and help them understand it in a new way. On Sunday, they would    discuss the experiences of the previous day and how to    integrate them into their lives.  <\/p>\n<p>    Friederikes practice, however, was illegal. Therapeutic    licences to use the drugs had been withdrawn by the Swiss    government around 1993, following the death of a patient in    France under the effect of ibogaine, another psychotropic drug.    (It was later determined that she died from an undiagnosed    heart condition.)  <\/p>\n<p>    The early LSD researchers had no way to look at what it was    doing inside the brain. Now we have brain scans. Robin    Carhart-Harris has carried out such studies with psilocybin,    LSD and MDMA. He tells me there are two basic principles of how    the classic psychedelics work. The first is disintegration: the    parts that make up different networks in the brain become less    cohesive. The second is desegregation: the systems that    specialise for particular functions as the brain develops    become, in his words, less different from each other.  <\/p>\n<p>    These effects go some way to explaining how psychedelics could    be therapeutically useful. Certain disorders, such as    depression and addiction, are associated with characteristic    patterns of brain activity that are difficult to break out of.    The brain kind of enters these patterns, pathological    patterns, and the patterns can become entrenched. The brain    easily gravitates into these patterns and gets stuck in them.    They are like whirlpools, and the mind gets sucked into these    whirlpools and gets stuck.  <\/p>\n<p>    Psychedelics dissolve patterns and organisation, introducing a    kind of chaos, says Carhart-Harris. On the one hand, chaos can    be seen as a bad thing, linked with things like psychosis, a    kind of storm in the mind, as he puts it. But you could also    view that chaos as having therapeutic value. The storm could    come and wash away some of the pathological patterns and    entrenched patterns that have formed and underlie the disorder.    Psychedelics seem to have the potential through this effect on    the brain to dissolve or disintegrate pathologically entrenched    patterns of brain activity.  <\/p>\n<p>    The therapeutic potential suggested by Carhart-Harriss brain    scan studies persuaded the UKs Medical Research Council to    fund the psilocybin trial for depression. Its too early to    evaluate its success, but the results so far have been    encouraging. Some patients are in remission now months after    having had their treatment, Carhart-Harris says. Previously    their depressions were very severe, so I think those cases can    be considered transformations. Im not sure if there are any    other treatments out there that really have that potential to    transform a patients situation after just two treatment    sessions.  <\/p>\n<p>    In the wake of MDMAs prohibition, American psychologist Rick    Doblin founded the Multidisciplinary Association for    Psychedelic Studies (MAPS) to support research aiming to    re-establish psychedelics place in medicine. When Swiss    psychiatrist Peter Oehen heard they were funding a study on    using MDMA to help people with post-traumatic stress disorder    (PTSD), he jumped on a plane to meet Doblin in Boston.  <\/p>\n<p>    Like Friederike, Oehen trained in psychedelic therapy while it    was legal in Switzerland in the early 1990s. Doblin agreed to    support a small study with 12 patients at Oehens private    practice in Biberist, a small town about half an hour by train    from the Swiss capital, Bern.  <\/p>\n<p>    Oehen thinks that MDMAs mood-elevating, fear-reducing and    pro-social effects make it a promising tool to facilitate    psychotherapy for PTSD. Many of these traumatised people have    been traumatised by some kind of interpersonal violence and    have lost their ability to connect, are distrustful, are    aloof, says Oehen. This helps them regain trust. It helps    build a sound and trustful therapeutic relationship. It also    puts the patient in a state of mind where they can face their    traumatic memories without becoming distressed, he says,    helping to start reprocess the trauma in a different way.  <\/p>\n<p>    When MAPSs first PTSD study in the USA was published in 2011,    the results were eye-opening. After two psychotherapy sessions    with MDMA, 10 out of 12 participants no longer met the criteria    for PTSD. The benefits were still apparent when the patients    were followed up three to four years after the therapy.  <\/p>\n<p>    Oehens results were less dramatic, but all of the patients who    had MDMA-assisted therapy felt some improvement. Im still in    touch with almost half of the people, he says. I can see    still people getting better after years going on in the process    and resolving their problems. We saw this at long-term    follow-up, that symptoms get better after time, because the    experiences enable them to get better in a different way to    normal psychotherapy. These effects  being more open, being    more calm, more willing to face difficult issues  this goes    on.  <\/p>\n<p>    In people with PTSD, the amygdala, a primitive part of the    brain that orchestrates fear responses, is overactive. The    prefrontal cortex, a more sophisticated part of the brain that    allows rational thoughts to override fear, is underactive.    Brain-imaging studies with healthy volunteers have shown that    MDMA has the opposite effects  boosting the prefrontal cortex    response and shrinking the amygdala response.  <\/p>\n<p>    Ben Sessa, a psychiatrist working around Bristol in the UK, is    preparing to carry out a study at Cardiff University testing    whether people with PTSD respond to MDMA in the same way. He    believes that early negative experiences lie at the root not    just of PTSD but of many other psychiatric disorders too, and    that psychedelics give patients the ability to reprocess those    memories.  <\/p>\n<p>    Ive been doing psychiatry for almost 20 years now and every    single one of my patients has a history of trauma, he says.    Maltreatment of children is the cause of mental illness, in my    opinion. Once a persons personality has been formed in    childhood and adolescence and into early adulthood, its very    difficult to encourage a patient to think otherwise. What    psychedelics do, more than any other treatment, he says, is    offer an opportunity to press the reset button and give the    patient a new experience of a personal narrative.  <\/p>\n<p>    Sessa is planning a separate study to test MDMA as a treatment    for alcohol dependency syndrome  picking up the trail of    Humphrey Osmonds LSD research 60 years ago.  <\/p>\n<p>    He believes psychiatry would look very different today if    research with psychedelics had proceeded unencumbered since the    1950s. Psychiatrists have since turned to antidepressants, mood    stabilisers and antipsychotics. These drugs, he says, help to    manage a patients condition, but arent curative, and also    carry dangerous side-effects.  <\/p>\n<p>    Weve become so used to psychiatry being a palliative care    field of medicine, Sessa says. That were with you for life.    You come to us in your early 20s with severe anxiety disorder;    Ill still be looking after you in your 70s.  <\/p>\n<p>      Weve become used to that. And I think were selling our      patients short.    <\/p>\n<p>    Will psychedelic drugs ever be ruled legal medicines again?    MAPS are supporting trials of MDMA-assisted psychotherapy for    PTSD in the USA, Australia, Canada and Israel, and they hope    they will have enough evidence to convince regulators to    approve it by 2021. Meanwhile, trials using psilocybin to treat    anxiety in people with cancer have been taking place at Johns    Hopkins University and New York University since 2007.  <\/p>\n<p>    Few psychiatrists I asked about the legal use of psychedelics    in therapy would give their opinions. One of the few who did,    Falk Kiefer, Medical Director at the Department of Addictive    Behaviour and Addiction Medicine at the Central Institute of    Mental Health in Mannheim, Germany, says he is sceptical about    the drugs ability to change patients behaviour. Psychedelic    treatment might result in gaining new insights, seeing the    world in a different way. Thats fine, but if it does not    result in learning new strategies to deal with your real world,    the clinical outcome will be limited.  <\/p>\n<p>    Carhart-Harris says the only way to change peoples minds is    for the science to be so good that funders and regulators cant    ignore it. The idea is that we can present data that really    becomes irrefutable, so that those authorities that have    reservations, we can start changing their perspective and bring    them around to taking this seriously.  <\/p>\n<p>    After 13 days under arrest, Friederike was released. She    appeared in court in July 2010, accused of violating the    narcotics law and endangering her clients, the latter of which    could mean up to 20 years imprisonment. A number of    neuroscientists and psychotherapists testified in her defence,    arguing that one portion of LSD is not a dangerous substance    and has no significant harmful effects when taken in a    controlled setting (MDMA was not included in the prosecutions    case).  <\/p>\n<p>    The judge accepted that Friederike had given her clients drugs    as part of a therapeutic framework, with careful consideration    for their health and welfare, and ruled her guilty of handing    out LSD but not guilty of endangering people. For the narcotics    offence, she was fined 2,000 Swiss francs and given a 16-month    suspended sentence with two years probation.  <\/p>\n<p>    I have been blessed by a very understanding lawyer and an    intelligent judge, she says. She even considers the woman who    reported her to the police a blessing, since the case has    allowed her to talk openly about her work with psychedelics.    She gives occasional lectures at psychedelic conferences, and    has written a book about her experience, which she hopes will    guide other therapists in how to work with the substances    safely.  <\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Read more: <\/p>\n<p><a target=\"_blank\" rel=\"nofollow\" href=\"http:\/\/www.abc.net.au\/triplej\/programs\/hack\/lsd-as-psychadelic-therapy\/8452814\" title=\"LSD as therapy: How scientists are reclaiming psychedelics - Hack ... - ABC Online\">LSD as therapy: How scientists are reclaiming psychedelics - Hack ... - ABC Online<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> At 6.30am on Thursday 29 October 2009, Friederike Meckel Fischers doorbell rang. There were ten policemen outside. They searched the house, put handcuffs on Friederike a diminutive woman in her 60s and her husband, and took them to a remand prison <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/psychedelics\/lsd-as-therapy-how-scientists-are-reclaiming-psychedelics-hack-abc-online\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[187761],"tags":[],"class_list":["post-189159","post","type-post","status-publish","format-standard","hentry","category-psychedelics"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/189159"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=189159"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/189159\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=189159"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=189159"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=189159"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}