{"id":174152,"date":"2016-10-27T11:56:37","date_gmt":"2016-10-27T15:56:37","guid":{"rendered":"http:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/longevity-wikipedia\/"},"modified":"2016-10-27T11:56:37","modified_gmt":"2016-10-27T15:56:37","slug":"longevity-wikipedia","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/human-longevity\/longevity-wikipedia\/","title":{"rendered":"Longevity &#8211; Wikipedia"},"content":{"rendered":"<p><p>      The word \"longevity\" is sometimes used as a synonym      for \"life expectancy\" in demography -      however, the term \"longevity\" is sometimes meant to refer      only to especially long-lived members of a population,      whereas \"life expectancy\" is always defined statistically as      the average number of years remaining at a given age. For      example, a population's life expectancy at birth is the same      as the average age at death for all people born in the same      year (in the case of cohorts). Longevity is best thought of      as a term for general audiences meaning 'typical length of      life' and specific statistical definitions should be      clarified when necessary.    <\/p>\n<p>      Reflections on longevity have usually gone beyond      acknowledging the brevity of human life and have included      thinking about methods to extend life. Longevity has been a      topic not only for the scientific community but also for      writers of travel, science      fiction, and utopian novels.    <\/p>\n<p>      There are many difficulties in authenticating the longest      human life span ever by modern verification      standards, owing to inaccurate or incomplete birth      statistics. Fiction, legend, and folklore have proposed or      claimed life spans in the past or future vastly longer than      those verified by modern standards, and longevity narratives and      unverified longevity claims frequently speak of      their existence in the present.    <\/p>\n<p>      A life      annuity is a form of longevity insurance.    <\/p>\n<p>      Various factors contribute to an individual's longevity.      Significant factors in life expectancy include gender, genetics, access to      health      care, hygiene, diet and nutrition, exercise, lifestyle, and crime rates. Below is a list of life      expectancies in different types of countries:[3]    <\/p>\n<p>      Population longevities are increasing as life      expectancies around the world grow:[1][4]    <\/p>\n<p>      The Gerontology Research Group      validates current longevity records by modern standards, and      maintains a list of      supercentenarians; many other unvalidated longevity      claims exist. Record-holding individuals      include:[citation      needed]    <\/p>\n<p>      Evidence-based studies indicate that longevity is based on      two major factors, genetics and lifestyle choices.[5]    <\/p>\n<p>      Twin studies have estimated that approximately 20-30% the      variation in human lifespan can be related to genetics, with      the rest due to individual behaviors and environmental      factors which can be modified.[6] Although      over 200 gene variants have been associated with longevity      according to a US-Belgian-UK research database of human      genetic variants,[7] these      explain only a small fraction of the heritability.[8] A 2012 study found that even      modest amounts of leisure time physical exercise can extend      life expectancy by as much as 4.5 years.[9]    <\/p>\n<p>      Lymphoblastoid cell lines established      from blood samples of centenarians have      significantly higher activity of the DNA repair protein PARP      (Poly ADP ribose polymerase)      than cell lines from younger (20 to 70 year old)      individuals.[10] The lymphocytic      cells of centenarians have characteristics typical of cells      from young people, both in their capability of priming the      mechanism of repair after H2O2      sublethal oxidative DNA damage and in their PARP      gene expression.[11] These findings      suggest that elevated PARP gene expression contributes to the      longevity of centenarians, consistent with the DNA damage theory of      aging.[12]    <\/p>\n<p>      A study of the regions of the world known as blue zones, where      people commonly live active lives past 100 years of age,      speculated that longevity is related to a healthy social and      family life, not smoking, eating a plant-based diet, frequent      consumption of legumes and nuts, and engaging in regular      physical activity.[13] In a      cohort study, the combination of a plant based diet, normal      BMI, and not smoking accounted for differences up to 15 years      in life expectancy.[14] Korean      court records going back to 1392 indicate that the average      lifespan of eunuchs was 70.0  1.76 years, which was      14.419.1 years longer than the lifespan of non-castrated men      of similar socio-economic status.[15] The      Alameda County Study hypothesized      three additional lifestyle characteristics that promote      longevity: limiting alcohol consumption, sleeping 7 to 8      hours per night, and not snacking (eating between meals), although      the study found the association between these characteristics      and mortality is \"weak at best\".[16] There are      however many other possible factors potentially affecting      longevity, including the impact of high peer competition,      which is typically experienced in large cities.[17]    <\/p>\n<p>      In preindustrial times, deaths at young and middle age were      more common than they are today. This is not due to genetics,      but because of environmental factors such as disease,      accidents, and malnutrition, especially since the former were      not generally treatable with pre-20th century medicine.      Deaths from childbirth were common in women, and many      children did not live past infancy. In addition, most people      who did attain old age were likely to die quickly from the      above-mentioned untreatable health problems. Despite this, we      do find many examples of pre-20th century individuals      attaining lifespans of 75 years or greater, including      Benjamin Franklin, Thomas      Jefferson, John Adams, Cato the Elder, Thomas      Hobbes, Eric of Pomerania, Christopher Polhem, and Michelangelo.      This was also true for poorer people like peasants or laborers. Genealogists will      almost certainly find ancestors living to their 70s, 80s and      even 90s several hundred years ago.    <\/p>\n<p>      For example, an 1871 census in the UK (the first of its kind,      but personal data from other censuses dates back to 1841 and      numerical data back to 1801) found the average male life      expectancy as being 44, but if infant mortality is      subtracted, males who lived to adulthood averaged 75 years.      The present male life expectancy in the UK is 77 years for      males and 81 for females, while the United States averages 74      for males and 80 for females.    <\/p>\n<p>      Studies have shown that black American males have the      shortest lifespans of any group of people in the US,      averaging only 69 years (Asian-American females average the      longest).[18] This reflects overall poorer      health and greater prevalence of heart disease, obesity,      diabetes, and cancer among black American men.    <\/p>\n<p>      Women normally outlive men, and this was as true in      pre-industrial times as today. Theories for this include      smaller bodies (and thus less stress on the heart), a      stronger immune system (since testosterone acts as an      immunosuppressant), and less tendency to engage in physically      dangerous activities.    <\/p>\n<p>      There is a current debate as to whether or not the pursuit of      longevity is a worthwhile health care goal for the United      States. Bioethicist Ezekiel Emanuel, who is also one of the      architects of ObamaCare,      has stated that the pursuit of longevity via the compression of morbidity      explanation is a \"fantasy\" and that life is not worth living      after age 75; therefore longevity should not be a goal of      health care policy.[19]      This has been refuted by neurosurgeon Miguel Faria, who states that life can be      worthwhile in healthy old age; that the compression of      morbidity is a real phenomenon; that longevity should be      pursued in association with quality of life.[20] Faria has discussed      how longevity in association with leading healthy lifestyles      can lead to the postponement of senescence as well as happiness and      wisdom in old age.[21]    <\/p>\n<p>      All of the biological organisms have a limited longevity, and      different species of animals and plants have different      potentials of longevity. Misrepair-accumulation aging theory      [22][23] suggests      that the potential of longevity of an organism is related to      its structural complexity.[24] Limited      longevity is due to the limited structural complexity of the      organism. If a species of organisms has too high structural      complexity, most of its individuals would die before the      reproduction age, and the species could not survive. This      theory suggests that limited structural complexity and      limited longevity are essential for the survival of a      species.    <\/p>\n<p>      Longevity traditions are      traditions about long-lived people (generally supercentenarians), and practices that      have been believed to confer longevity.[25][26] A comparison and      contrast of \"longevity in antiquity\" (such as the Sumerian King List, the genealogies of Genesis, and the      Persian Shahnameh) with \"longevity in historical      times\" (common-era cases through twentieth-century news      reports) is elaborated in detail in Lucian Boia's      2004 book Forever Young: A Cultural History of Longevity      from Antiquity to the Present and other sources.[27]    <\/p>\n<p>      The Fountain of Youth reputedly restores      the youth of anyone who drinks of its waters. The New      Testament, following older Jewish tradition, attributes      healing to the Pool of Bethesda when the waters are      \"stirred\" by an angel.[28] After the      death of Juan Ponce de Len, Gonzalo Fernndez de      Oviedo y Valds wrote in Historia General y Natural de      las Indias (1535) that Ponce de Len was looking for the      waters of Bimini to      cure his aging.[29] Traditions      that have been believed to confer greater human longevity      also include alchemy,[30] such      as that attributed to Nicolas Flamel. In the modern era, the      Okinawa      diet has some reputation of linkage to exceptionally high      ages.[31]    <\/p>\n<p>      More recent longevity claims are subcategorized by      many editions of Guinness World Records      into four groups: \"In late life, very old people often tend      to advance their ages at the rate of about 17 years per      decade .... Several celebrated super-centenarians (over 110      years) are believed to have been double lives (father and      son, relations with the same names or successive bearers of a      title) .... A number of instances have been commercially      sponsored, while a fourth category of recent claims are those      made for political ends ....\"[32] The      estimate of 17 years per decade was corroborated by the 1901      and 1911 British censuses.[32] Mazess      and Forman also discovered in 1978 that inhabitants of      Vilcabamba, Ecuador, claimed      excessive longevity by using their fathers' and grandfathers'      baptismal entries.[32][33]Time magazine      considered that, by the Soviet Union, longevity had been      elevated to a state-supported \"Methuselah cult\".[34]Robert Ripley      regularly reported supercentenarian claims in Ripley's Believe It or      Not!, usually citing his own reputation as a fact-checker      to claim reliability.[35]    <\/p>\n<p>      The U.S. Census Bureau view on      the future of longevity is that life expectancy in the      United      States will be in the mid-80s by 2050 (up from 77.85 in      2006) and will top out eventually in the low 90s, barring      major scientific advances that can change the rate of human      aging itself, as opposed to merely treating the effects of      aging as is done today. The Census Bureau also predicted that      the United States would have 5.3 million people aged over 100      in 2100. The United Nations has also made projections      far out into the future, up to 2300, at which point it      projects that life expectancies in most developed countries      will be between 100 and 106 years and still rising, though      more and more slowly than before. These projections also      suggest that life expectancies in poor countries will still      be less than those in rich countries in 2300, in some cases      by as much as 20 years. The UN itself mentioned that gaps in      life expectancy so far in the future may well not exist,      especially since the exchange of technology between rich and      poor countries and the industrialization and development of      poor countries may cause their life expectancies to converge      fully with those of rich countries long before that point,      similarly to the way life expectancies between rich and poor      countries have already been converging over the last 60 years      as better medicine, technology, and living conditions became      accessible to many people in poor countries. The UN has      warned that these projections are uncertain, and cautions      that any change or advancement in medical technology could      invalidate such projections.[36]    <\/p>\n<p>      Recent increases in the rates of lifestyle diseases, such as obesity, diabetes, hypertension,      and heart disease, may eventually slow or      reverse this trend toward increasing life expectancy in the      developed world, but have not yet done so. The average age of      the US population is getting higher[37] and      these diseases show up in older people.[38]    <\/p>\n<p>      Jennifer Couzin-Frankel examined how much mortality from      various causes would have to drop in order to boost life      expectancy and concluded that most of the past increases in      life expectancy occurred because of improved survival rates      for young people. She states that it seems unlikely that life      expectancy at birth will ever exceed 85 years.[39]Michio Kaku argues that genetic engineering, nanotechnology and future breakthroughs      will accelerate the rate of life expectancy increase      indefinitely.[40] Already genetic engineering      has allowed the life expectancy of certain primates to be      doubled, and for human skin cells in labs to divide and live      indefinitely without becoming cancerous.[41]    <\/p>\n<p>      However, since 1840, record life expectancy has risen      linearly for men and women, albeit more slowly      for men. For women the increase has been almost three months      per year, for men almost 2.7 months per year. In light of      steady increase, without any sign of limitation, the      suggestion that life expectancy will top out must be treated      with caution. Scientists Oeppen and Vaupel observe that      experts who assert that \"life expectancy is approaching a      ceiling ... have repeatedly been proven wrong.\" It is thought      that life expectancy for women has increased more      dramatically owing to the considerable advances in medicine      related to childbirth.[42]    <\/p>\n<p>      Mice have been genetically engineered to live twice as long      as ordinary mice. Drugs such as deprenyl are a part of the      prescribing pharmacopia of veterinarians specifically to      increase mammal lifespan. A large plurality of research      chemicals have been described at the scientific literature      that increase the lifespan of a number of species.    <\/p>\n<p>      Some argue that molecular nanotechnology      will greatly extend human life spans. If the rate of increase      of life span can be raised with these technologies to a level      of twelve months increase per year, this is defined as      effective biological immortality and is      the goal of radical life extension.    <\/p>\n<p>      Currently living:    <\/p>\n<p>      Non-living:    <\/p>\n<p>      Certain exotic organisms do not seem to be subject to aging      and can live indefinitely. Examples include Tardigrades and Hydras. That      is not to say that these organisms cannot die, merely that      they only die as a result of disease or injury rather than      age-related deterioration (and that they are not subject to      the Hayflick limit).    <\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Read the original:<br \/>\n<a target=\"_blank\" href=\"https:\/\/en.m.wikipedia.org\/wiki\/Longevity\" title=\"Longevity - Wikipedia\">Longevity - Wikipedia<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> The word \"longevity\" is sometimes used as a synonym for \"life expectancy\" in demography - however, the term \"longevity\" is sometimes meant to refer only to especially long-lived members of a population, whereas \"life expectancy\" is always defined statistically as the average number of years remaining at a given age.  <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/human-longevity\/longevity-wikipedia\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[24],"tags":[],"class_list":["post-174152","post","type-post","status-publish","format-standard","hentry","category-human-longevity"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/174152"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=174152"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/174152\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=174152"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=174152"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=174152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}