{"id":1127182,"date":"2024-07-20T04:22:05","date_gmt":"2024-07-20T08:22:05","guid":{"rendered":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/uncategorized\/inside-the-texas-crime-lab-thats-cracked-hundreds-of-cold-cases-texas-monthly\/"},"modified":"2024-07-20T04:22:05","modified_gmt":"2024-07-20T08:22:05","slug":"inside-the-texas-crime-lab-thats-cracked-hundreds-of-cold-cases-texas-monthly","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/dna\/inside-the-texas-crime-lab-thats-cracked-hundreds-of-cold-cases-texas-monthly\/","title":{"rendered":"Inside the Texas Crime Lab Thats Cracked Hundreds of Cold Cases &#8211; Texas Monthly"},"content":{"rendered":"<p><p>    Allison Brocato last saw her sister alive on the afternoon of    January 13, 1995. It was a Friday, and Catherine Edwards,    Allisons 31-year-old identical twin, had just gotten off work    at Price Elementary School, in Beaumont. On her way home,    Edwards stopped to pick up her beagle, whom Brocato had been    dogsitting. She lingered a few minutes to chat and to play with    Brocatos infant daughter. She seemed kind of sad that day,    Brocato would later recall. I think she had had a fight with    an ex-boyfriend the night before.  <\/p>\n<p>    Brocato and Edwards considered themselves best friends. After    graduating from Lamar University, they both got jobs as public    school teachers and moved into a modest town house in west    Beaumont, where they lived together until Brocato got married.    The sisters looked so alikea bit shy of five feet tall, slim,    with pale skin and shy smilesthat their high school yearbook    had mixed up their photos. Later, as teachers, they would    occasionally fool their students by pretending to be each    other.  <\/p>\n<p>    The two women spoke again by phone that evening, as they    usually did before bed. Edwards had decided to break off all    contact with her ex-boyfriend. The sisters both planned to be    at the familys traditional Saturday lunch the next day at    their parents house, but Edwards never showed up. When her    parents drove to her town house to check on her, they found    their daughters body in the second-floor bathroom, slumped    over the tub. She was nude from the waist down, and her wrists    were handcuffed behind her back. Her father sounded frantic    when he told Brocato what theyd found. He said, Your    sisters dead, your sisters dead.  <\/p>\n<p>    The brutal murder made front-page news for days in Beaumont,    where Edwards was known as a dedicated teacher and a lifelong    Presbyterian. She volunteered at St. Elizabeth hospital and    served as a mentor for the I Have a Dream Program    scholarship. Neighbors remembered her walking her dog each    evening. She was loved by everybody, recalled Steve Thrower,    a now retired investigator for the Jefferson County District    Attorneys Office who was assigned to assist Beaumont Police    Department detectives with the case. Great family. Never had    any kind of criminal issue. Usually that really shrinks your    suspect pool.  <\/p>\n<p>    Crime scene investigators saw no signs of forced entry at the    town house. Either Edwards had left her door unlocked or she    had let her killer in. During the autopsy, a forensic    pathologist took a vaginal swab that collected semen, which was    also found on the comforter of her bed. The assailant appeared    to have raped Edwards and drowned her in the bathtub.    Detectives collected DNA samples from dozens of potential    suspects, including Edwardss ex-boyfriend and several of her    colleagues at Price Elementary. None matched the perpetrators    DNA. Nor did the DNA match anyone in the Federal Bureau of    Investigations recently created Combined DNA Index System, a    national database of genetic profiles from convicted criminals,    forensic evidence, and missing persons.  <\/p>\n<p>    As the investigation dragged on month after month without any    progress, the case slowly went cold. No arrest was made. For    the next quarter century, the semen collected from the Edwards    murder sat in a series of evidence-room freezers. Encoded in    its DNA was the identity of the killer. But unless he left    behind evidence at another crime scene, it seemed unlikely he    would ever be caught.  <\/p>\n<p>    Then, in 2020, a Texas scientist and entrepreneur named David    Mittelman approached Beaumont police with an intriguing offer.    Two years before, Mittelman had opened a private DNA lab in The    Woodlands, an affluent master-planned community north of    Houston. He named the company Othram, after the defensive wall of a    fortress in J.R.R. Tolkiens The Lord of the Rings.    (We serve a public-safety function, so theres a bit of a    loose connection there, Mittelman explained.) The lab    specializes in forensic genetic genealogy, a powerful new    investigative method that combines whole-genome DNA sequencing    with traditional genealogical research based on archival    documents such as birth and death records. The technique first    came to widespread public attention in 2018, when California    detectives used it to identify Joseph James DeAngelo Jr. as    the Golden State Killer, a serial murderer    and rapist who had eluded police for decades.  <\/p>\n<p>    When Beaumont detective Aaron Lewallen received Mittelmans    offer to assist with any unsolved crimes, he immediately    thought of the Catherine Edwards murder. This was Beaumonts    most high-profile homicide, recalled Lewallen, a laconic    26-year veteran who had developed a specialty in cold cases.    With the original detectives ruling out so many of the people    who were close to her in her life, it had really become a    whodunit. At Lewallens request, local officials agreed to pay    Othram about $10,000 to conduct new DNA testing. A few weeks    later, a FedEx courier dropped off a Styrofoam box at the labs    headquarters. Inside, chilled by an ice pack, was a piece of    floral-print fabric from Edwardss comforter and a vaginal swab    from the posthumous rape kit.  <\/p>\n<p>    Unless he was dead or in jail, the man who killed Edwards    remained at large. Perhaps he was still in Beaumont. Perhaps he    had moved away and started a new life. He had concealed his    crime for nearly three decades; surely, he must have thought,    the police had given up on the case. There was no way for him    to know that in the early 2020s, a small group of detectives    and scientists had dedicated themselves to unmasking him.  <\/p>\n<p>    On a cool gray morning last fall, I drove thirty miles north    from Houston to tour Othrams lab. The company rents space in a    four-story building beside a lake in a heavily wooded office    park off the aptly named Technology Forest Boulevard. David    Mittelman greeted me in the elegantly furnished lobby. Wearing    jeans and a rumpled black polo shirt, with disheveled hair and    beard stubble, the 43-year-old scientist looked like he had    been up all night. He was joined by his 45-year-old wife,    Kristen, Othrams chief development officer. A lean, angular    brunette who has moonlighted as a competitive bodybuilder, she    was dressed in stylish athleisure wear. The couple met at    Baylor College of Medicine, in Houston, where they both earned    doctoratesDavid in molecular biophysics and Kristen in    biochemistry.  <\/p>\n<p>    Together the two have turned Othram into arguably the worlds    leading forensic genetic genealogy lab. Over the past six    years, the company has been publicly credited with helping to    solve nearly 350 cases, including murders, rapes, and    unidentified bodies. That number represents only a fraction of    the thousands of cases it has actually assisted on, David told    me, because some law enforcement officials prefer not to    disclose Othrams role in their investigations. (For    comparison, Virginia-based Parabon    NanoLabs, another well-known company in the field, says it    has assisted in more than 315 cases.) Othram has ongoing    relationships with agencies around the world, including the    Australian Federal Police, the Royal Canadian Mounted Police,    and the Texas Rangers.  <\/p>\n<p>    Kristen led me through two sets of key cardoperated double    doors and down a long corridor lined with floor-to-ceiling    glass walls. On the left was a series of research labs, where    Othram scientists were exploring new ways to extract and    analyze DNA. On the right were the forensic labs, where masked    technicians in paper gowns and hairnets bent over hooded lab    benches, working on crime scene evidence. In one room, a femur,    stained dark from many decades underground, sat on a sheet of    butcher paper. Because of privacy concerns, the Mittelmans    couldnt reveal anything about the case other than that the    bone belonged to a child.  <\/p>\n<p>    Multiple times a day, packages containing crime scene    evidenceblood, bones, hair, nail clippings, teetharrive at    the lab. An Othram employee photographs the packages and then    uploads the images to the companys online portal, where law    enforcement agencies can keep tabs on their evidence. Each step    of the process is documented to maintain a chain-of-custody    record for use in subsequent legal proceedings. Especially with    cold cases, tracking the circuitous route that evidence    takesfrom a crime scene to a police property room to a    forensic-testing lab and back to the property roomis critical.    To discredit DNA evidence, defense attorneys will pounce on any    potential contamination.  <\/p>\n<p>    Othram technicians determine whether there is sufficient DNA to    build a profile from the forensic material they receive. Unlike    the cheek swabs used by medical testing companies, crime scene    evidence often contains genetic samples from multiple    individuals, and it can include plant or animal DNA. It also    deteriorates over time. No matter how well the investigators    try to keep it, its organic material, David explained. There    are things that can developbacteria and other kinds of things.    So that makes it tougher to read the data.  <\/p>\n<p>    The lab ends up rejecting about a third of the evidence it    receives. Better to wait until forensic technology improves,    the Mittelmans believe, than make a futile bid to obtain a    genetic profile. Each test uses up a portion of scarce crime    scene DNA. Some forensic labs have destroyed entire samples    without obtaining a profile. In medicine, you would never    treat a patient if you had no idea whether it would help or    not, Kristen said. If youre running the DNA on assays that    dont work, youre consuming it, which means youre consuming    someones last chance at justice.  <\/p>\n<p>    Over time, Othram researchers have developed proprietary    methods for obtaining profiles from ever-smaller amounts of    DNA. In 2021 the lab established a new milestone by using just    120 picograms of DNAabout fifteen human cells worth of    genetic materialto help identify the man who raped and    murdered a fourteen-year-old Las Vegas girl, Stephanie    Isaacson.  <\/p>\n<p>    In the Edwards case, Othram technicians determined that the    semen found on the vaginal swab had a high likelihood of    yielding a strong DNA profile. They used a technique called    differential extraction to distinguish the suspects sperm from    Edwardss skin cells and other foreign material. Then they ran    the sample through an Illumina NovaSeq 6000, a million-dollar    whole-genome sequencer about the size of an office copier.    Othrams custom software combed through the data for genetic    markersunique DNA sequences that could be used to identify the    suspect. To build a useful profile, Othram investigators need    to find hundreds of thousands of such markers. In the Edwards    case, they found more than half a million.  <\/p>\n<p>    The genetic profile they developed was then uploaded, in the    form of a digital text file, to a website called GEDmatch.    Founded in 2010, the site maintains a database of more than 1.5    million profiles voluntarily submitted by users around the    world, many of them hoping to find distant relatives. About 30    percent of those users have consented to law enforcement using    their personal information to identify violent criminals. The    website says it has helped solve more than four hundred    cases.  <\/p>\n<p>    The closest genetic match to the suspect in the database was a    woman living in Louisiana. Based on their quantity of DNA in    common, they appeared to be second cousins, which meant they    shared a pair of great-grandparents. The woman might never have    met the suspect or even known of his existence, but she had    just become an unwitting genetic informer for the Beaumont    Police Department. The information she provided was about to    break the Catherine Edwards case wide open.  <\/p>\n<p>    David Mittelmans path to Othram began in 1997, when he landed    an internship at the University of Texas Southwestern Medical    Center, in Dallas, working on the Human Genome Projectthe thirteen-year, $3 billion    effort to map our entire genetic composition. At the time, he    was a precocious student at Pearce High School, in nearby    Richardson. It just seemed like an exciting opportunity to    learn more about what all these pieces of genetic information    meant, Mittelman said. Intuitively, I could sense that this    was going to be a real driver in changing how society    works.  <\/p>\n<p>    He continued working on the project while attending college at    UT Dallas. His job was to build and program robots that would    automate various lab processes. Genomics in the nineties was    very labor-intensive, he explained. Back then, it was a lot    of human stuff and a little bit of computer stuff. That has    kind of flipped now. After earning a bachelors degree in    neuroscience from UT Dallas and his doctorate, David took a    professorship at Virginia Tech, where he won a National    Institutes of Health grant to research the use of genetic data    for medical diagnosis and treatment.  <\/p>\n<p>    One day in the early 2010s, a representative from the FBI    visited Virginia Tech to speak about the role of DNA in    criminal investigations. Humans share roughly 99.9 percent of    our genetic material, but all of us have DNA    sequencestypically along portions of the genome whose    functions arent yet well understoodthat feature enough    mutations to distinguish us as individuals. By the mid-1980s,    scientists had identified the location of thirteen such    sequences, also known as markers, which became known as a DNA    fingerprint. (The number has since expanded to twenty markers.)    Because the odds of any two unrelated individuals sharing the    same DNA fingerprint are infinitesimal, this test has become    the standard in international law enforcement. But the method    works only if police have a suspect from whom to collect a DNA    sample. If the culprit remains at large, as in the Catherine    Edwards murder, the method is all but useless.  <\/p>\n<p>    During the discussion, David realized that the field of    forensics was woefully behind the times. Rather than relying on    twenty markers, scientists could now use whole-genome    sequencing to obtain hundreds of thousands. Sequencing an    entire genome would give police detailed information about a    suspects ethnic background, eye color, sex, and skin    pigmentation. It would be like going from monochrome to    Technicolor. The FBI guy asked me how much it would cost, and    I said thirty thousand to forty thousand dollars, David    recalled. He laughed at me and left. At that time, the    economics didnt make any sense.  <\/p>\n<p>    David set aside the idea and continued working on the medical    side of genetics. In 2012 he cofounded Arpeggi, a tech start-up    that created software to help physicians sift through the    avalanche of data produced by whole-genome sequencing. Within a    year the company was acquired by Gene by Gene,    the Houston-based parent company of the popular genetic testing    website FamilyTreeDNA. David resigned from Virginia Tech    and moved back to Texas to become Gene by Genes chief    scientific officer. This gave him an introduction to the world    of direct-to-consumer DNA testing, which had exploded in    popularity. Although he soon left to work at a series of other    biomedical companies, his experience at Gene by Gene planted    the seed for Othram.  <\/p>\n<p>    The costs were coming down on sequencing, he said. I had    learned a lot at FamilyTreeDNA about how people interconnect    genetically. It was, like, maybe the economics are where they    need to be. The technology has largely been solved for medical    diagnostics. So how can we take this powerful technology to do    something good in the world? And thats what shifted my mindset    back to the problem of forensics. David soon discovered that    there were hundreds of thousands of unsolved murders and tens    of thousands of unidentified bodies in the United States alone.    Crime labs nationwide were struggling to keep up with new    investigations, let alone decades-old cold cases. The more    David learned, the more outraged he became. People do not    understand the magnitude of this problem, he told me.  <\/p>\n<p>    In 2018, with $4 million in seed money led by a San    Franciscobased investment fund, David set up shop in a    one-story office building in The Woodlands, a five-minute drive    from his house. Kristen initially declined to take a job at the    company because it seemed like such a long shot. I told him    that he had lost his mind, she said. Who is going to give you    evidence? Were medical people. We have no policing background    whatsoever. And youre going to build a forensic lab?  <\/p>\n<p>    Genetic genealogy is such a young field that few regulations or    accreditation standards exist. David knew that he would have to    win the trust of law enforcement agencies unfamiliar with    whole-genome sequencing. He would have to convince them that    such testing was worth the initial price tag of $10,000 per DNA    sample. Perhaps most important, he would need to prove that his    work would stand up in a courtroom.  <\/p>\n<p>    Brandon Bess, a bluff, plainspoken Texas Ranger who lives in    the small town of Anahuac, midway between Beaumont and Houston,    visited the lab shortly after it opened. It was David and,    like, three other people working there at the time, and it was    kind of a dump, he recalled. My first impression of David was    that he looked like a mad scientist. He had on a T-shirt that    was too small and looked like he hadnt slept in about three    days. He had hair going all over the place, a ripped-up pair of    jeans, and a pair of tennis shoes. But he was very focused. And    he could talk. (David told me Besss impression was    accurateearly on at Othram, he would often work for days with    little sleep.)  <\/p>\n<p>    Whole-genome sequencers such as the NovaSeq 6000 were built to    analyze fresh DNA obtained from cheek swabs. Othram had to    design lab processes capable of extracting data from damaged    and degraded genetic material, then create software to analyze    it. David hired engineers and molecular biologists with    experience pulling DNA from inhospitable media, such as    formaldehyde and paraffin, which are known to scramble genetic    information. We developed a number of tools, both in the    laboratory and on the computer side, that allowed us to get    reproducible and predictable success from forensic samples, he    said.  <\/p>\n<p>    In 2019 Othram built a DNA profile that enabled investigators    to identify a skeleton discovered in an Idaho cave in 1979 as    the remains of Henry Loveless, a bootlegger and    counterfeiter who was murdered in 1916. Then, in 2020, the lab    received a flood of publicity after helping to solve the 1974        murder of Carla Walker, a seventeen-year-old Fort Worth    high school student.  <\/p>\n<p>    The company soon began announcing new successes on an almost    weekly basis. It helped identify the perpetrators of the 1974    abduction and murder of a five-year-old girl from Montana; the 1977    rape and murder of a 77-year-old North Carolina woman; and the    1984 rape and murder of a nine-year-old girl in Canada. There were    also many John and Jane Does it helped identify. A victim of a traffic accident on a    Pennsylvania road in 1987. A corpse fished out of a lake in Washington    State in 1994. A     woman who mysteriously drowned in a Pecos hotel swimming    pool in 1966.  <\/p>\n<p>    To publicize Othrams work, Mittelman capitalized on Americas    fascination with true crime. He became a regular speaker at    CrimeCon, the popular annual true-crime    conference, and he consulted on a 2021 episode of Law and Order: Special Victims    Unit that featured a forensic genealogy lab inspired    by Othram. The company hosts a private genetic database where users can    upload their DNA data in hopes of helping solve a crime, and it    has launched dozens of crowdfunding campaigns to finance work    on cold cases around the country. On social media, Othram    advertises its successful investigations and solicits    donations.  <\/p>\n<p>    Among the companys earliest large donors was Carla Davis, a self-taught genealogist from    Mississippi who came across one of Othrams fund-raising    campaigns on LinkedIn in late 2020. She gave tens of thousands    of dollars that helped fund the identification of several sets    of remains found in Mississippi between 1977 and 2020. Law    enforcement agencies there are so underfunded, Davis recently    told me over Zoom from her home in Dubai, where she and her    husband have a real estate investment company. I was just    trying to help give my home state the technology to solve their    cases.  <\/p>\n<p>    After Davis continued to lend Othram both financial support and    genealogical expertise, the company hired her two years ago to    lead its thirteen-employee genealogy team. Working remotely,    Davis and her team have assisted in more than four hundred    cases. Its really exciting to be part of this moment, she    said. Were going to see so many more companies using this    technology and more cases being solved. I think were not going    to have cold cases in the future.   <\/p>\n<p>    According to the business-research platform Crunchbase, over    the past six years Othram has raised nearly $36 million in    venture capital. Among its biggest investors is Gigafund, the    Austin-based firm best known for its stake in several of Elon    Musks companies, including the Boring Company, Neuralink, and    SpaceX. Our investors are interested in the decade-long    transformational shift in the way forensic genetic testing is    done, David said. They understand its a long game. Like    many tech start-ups, Othram has spent its early years burning    through money in pursuit of its goals. In 2022 it moved to    another office building in The Woodlandswith quadruple the lab    space and additional room for a staff that now numbers more    than sixty. It currently charges law enforcement agencies only    enough to cover the incremental costs of an investigation,    though David said that wont remain the case as economies of    scale bring those costs down. He also plans to reach    profitability by licensing the companys software and processes    to other forensic labs.  <\/p>\n<p>    Othram has attracted criticism for what some consider its    sharp-    elbowed business practices. In January, the company announced    an exclusive partnership with FamilyTreeDNA, one of only two    major databases that grant law enforcement agencies access to    their profiles. (The other is GEDmatch, which is owned by    Netherlands-based biotechnology company Qiagen.) Labs    hoping to use FamilyTreeDNA to identify a suspect now have to    use Othram software. In the wake of the announcement, the    nonprofits DNA Doe Project and Intermountain Forensics temporarily stopped using    FamilyTreeDNA. They were seeking additional clarification, so    I personally got on the phone with them to talk them through    the partnership, Mittelman said. Both organizations have since    resumed working with FamilyTreeDNA.  <\/p>\n<p>    Meanwhile, the field of genetic genealogy has come under fire    from civil liberties groups concerned about the privacy of    users who upload their DNA information to websites such as    GEDmatch, and from bioethicists who worry about the dearth of    federal regulation. DNA is valuableto governments, to    bioscience companies, and to the policeand genetic databases,    like anything else that lives online, can be hacked. Mittelman    says he shares some of these concerns but points out that users    submit their DNA to these sites voluntarily and can opt out of    law enforcement searches.  <\/p>\n<p>    Forensic genetic genealogy relies on a certain degree of    ethical ambiguity. After a lab such as Othram identifies a    potential culprit, detectives must then collect the suspects    DNAoften surreptitiouslyin order to match it to DNA found at    the crime scene. Usually this is done by taking items from a    suspects garbage, as in the Golden State Killer case.    According to long-standing legal precedent, police typically do    not need a warrant to obtain evidence from garbage that has    been left on the curb. So far, courts have ruled that the same    holds true for the DNA in that trash.   <\/p>\n<p>    Some experts, including Teneille Brown, a law professor at the    University of Utah who has written about forensic genetic genealogy,    argue that courts should declare the furtive seizing of    someones DNA to be a violation of the Fourth Amendments    prohibition against unreasonable searches and seizures.    Obtaining someones entire genetic profile, after all,    constitutes a significantly greater invasion of privacy than    merely rummaging through their food scraps. DNA is not    garbage, so we shouldnt be treating it like that, Brown told    me. The American Civil Liberties Union has filed several amicus    briefs opposing warrantless DNA collection.  <\/p>\n<p>    Mittelman professes not to concern himself with such    constitutional questions, deferring to the legal experts. For    him and most law enforcement agencies, what matters is the    ability to identify a victim or a suspect. At that Othram has    proved remarkably successful. During one week in late May, the    lab announced its role in solving six cases, including one    murder and five unidentified bodies. And it is increasingly    called upon to assist in active investigations. Earlier this    year, Othram helped identify Victor Antonio Martinez-Hernandez,    a fugitive from El Salvador, as a suspect in the 2023 murder of    Maryland mother Rachel Morin. Martinez-Hernandez was arrested    in June and charged with murder and rape.  <\/p>\n<p>    With genetic-testing technology improving rapidly, the biggest    remaining hurdle to solving cold cases may be money. These    cases move at the speed of funding, David told me. In the    United States, the largest single source of law enforcement    funding is the federal government. This is where Kristen    Mittelman comes in. After earning her doctorate, she worked as    an intellectual-property specialist at Houston law firm Baker    Botts before moving with David to Virginia Tech, where she    became the universitys director of grants and contracts. In    2021 Kristen joined Othram, where she spends much of her time    in Washington, D.C., lobbying Congress for money. He was    struggling with funding, she told me. And I knew I was good    at getting federal funding.  <\/p>\n<p>    Thanks in part to Kristens efforts, Republican congressman    Kelly Armstrong, of North Dakota, introduced the Carla Walker Act in 2022.    Named after the Fort Worth teenager whose murder Othram helped    solve, the bill would provide $20 million in grants to law    enforcement agencies for forensic genetic genealogy    investigations. The bill has yet to make it out of committee.    Last August, U.S. senator John Cornyn traveled to The Woodlands to    meet the Mittelmans and tour Othram. During a press conference    at the lab, he promised to introduce a version of the Carla    Walker Act in the Senate. This sort of technology is critical    to solving crime and protecting public safety, he declared.  <\/p>\n<p>    Kristen is working with Cornyns office to draft the proposed    legislation, which she says will include reporting requirements    to assess the work of forensic genetic genealogy labs. The    Mittelmans worry about the damage an unscrupulous lab could do    to the reputation of their nascent industry. There are so many    companies out there selling the quickest way to make a profile    with fewer markers, Kristen said. Because there are currently    no metrics of success in forensics, people are taking    shortcuts. This needs to be done predictably. You need to start    collecting metrics, find technologies that work, and fund the    implementation of those technologies.  <\/p>\n<p>    After identifying the likely second cousin of Catherine    Edwardss killer, Othram passed its findings to Beaumont    detective Aaron Lewallen, who was now working with Brandon    Bess, the Texas Ranger. Othram has an in-house genealogy team,    but some law enforcement agencies use their own genealogist. In    this case, Lewallen happened to know one willing to work for    free: his wife.  <\/p>\n<p>    Tina Lewallen, a detective in the auto crimes division of    Beaumont Police Department, first got interested in genealogy    in the nineties, to explore her family history. When    direct-to-consumer DNA testing became available, she submitted    a cheek swab to AncestryDNA. The results ruled out the    French heritage her family had always claimed. That fascinated    me, because DNA doesnt lie, Tina recently told me in her    windowless Beaumont office, which was decorated with mug shots    of suspected car thieves. A pair of rose-pink handcuffs, a gift    from her husband, were clipped to her belt.  <\/p>\n<p>    Othram provided Tina with a list of the suspects closest    relatives on GEDmatch, along with how much DNA each shared and    their likely familial relationship. The listed email address    for one of the relatives, Paul Thomas LaPoint, led to his    daughter-in-law, a professional genealogist named Shera LaPoint    who lives in the small town of Bunkie, Louisiana, about eighty    miles northwest of Baton Rouge. Shera had submitted Paul    Thomass DNA to GEDmatch years before. Stunned to learn that    her father-in-law was related to a suspected killer, she    volunteered to help the Beaumont detectives with the case.    After vetting her, the Lewallens brought Shera onto the team,    forwarding the list they received from Othram.  <\/p>\n<p>    It was a bunch of Cajun names, many of them people that I    knew, because a lot of them are also into genealogy, Shera    told me. Forensic genetic genealogy investigations start by    identifying the most recent common ancestor between the suspect    and their closest genetic match. In the Edwards case, the    search was complicated by the suspects Cajun ancestry. Cajuns    descend from a small colony of French Canadians who were    expelled by the British in the mid-1700s and found refuge in    Louisiana. Over the centuries, some members of the tight-knit    Catholic community engaged in intermarriage with close    relatives, such as cousins. As a result, performing genetic    genealogy in Cajun families can be notoriously complex. Shera    and her father-in-law, for instance, share thirteen ancestors.    In a perfect world, when you look at DNA matches for a person    who has tested on AncestryDNA or FamilyTreeDNA, you should be    able to separate their four grandparents lines, Shera said.    But when youre looking at Cajun DNA, its very difficult,    because your maternal grandmother may be related to your    paternal grandfather. So it makes it very difficult to find the    common ancestor youre looking for.  <\/p>\n<p>    Using Ancestry.com, which bills itself as the worlds largest    genealogy site, Shera and Tina built a family tree for the    presumed second cousin, going back in time until they    identified her eight great-grandparents. Then they started    working back down, following branches of the tree in search of    a descendant who lived in Beaumont when Catherine Edwards was    killed. But that effort led to a dead end. Because the family    was Cajun, they realized, the presumed second cousin might    actually be the suspects third cousin. Shera and Tina were    forced to go back another generation, to the womans    great-great-grandparents. They ended up with a family tree of    more than 7,400 names.  <\/p>\n<p>    To narrow the search, they asked Aaron Lewallen and Bess to    request DNA samples from living members of these families. The    detectives spent days driving around Texas and Louisiana,    collecting dozens of cheek swabs. I thought it was going to be    difficult to talk people out of their DNA, Aaron recalled.    But youd be amazed how many people are out there interested    in helping out. Theres a lot of true-crime buffs. Each swab    was sent to Othram, which sequenced the DNA and uploaded it to    GEDmatch. The results let Shera and Tina rule out entire family    lines.  <\/p>\n<p>    About three months into the investigation, Sheras research led    to a husband and wife whod lived in Beaumont in the sixties.    Birth records indicated that the couple had two sons who would    have been about the same age as Edwards. Shera texted Tina and    Aaron, who ran the names of the couples sons through a    criminal background search. One of the brothers came up clean,    but the other had a record. In 1981, Clayton Bernard Foreman    had pleaded guilty to aggravated assault in Beaumont. I was    like, holy shit, Aaron recalled. Its him.  <\/p>\n<p>    According to the case file, Foreman, then a 21-year-old Nabisco    salesman, had been driving through Beaumont when he saw a young    woman whod had car trouble. Foreman stopped to offer her a    ride, claiming to be a cop. He drove the woman to a secluded    area, threatened to cut her throat with a knife, tied her hands    behind her back with a belt, and raped her. About two weeks    later, the traumatized woman went to the police. Foreman    readily confessed, explaining that he had been out drinking    and just got carried away. In exchange for pleading guilty to    aggravated assault, he received three years of probation. Aaron    soon learned that Foreman and Edwards were three years apart at    Forest Park High School. Edwards and her twin sister, Allison,    had even been bridesmaids at Foremans 1982 wedding.  <\/p>\n<p>    An online search revealed that Foreman, now 61, was living with    his fiance in a suburb of Columbus, Ohio, where he worked as    an Uber driver. An officer from the local police department was    dispatched to collect bags of trash from outside Foremans    house. Several of the discarded items, including dental floss    and plastic tableware, were sent to the Texas Department of    Public Safety crime lab in Houston for testing. Foremans DNA    was a clear match to that of the semen from Edwardss vaginal    swab.  <\/p>\n<p>    On April 29, 2021, Aaron and Bess flew to Ohio, where they met    Foreman face-to-face at the local police station. A video    recording of the interrogation shows an obese man with a    receding hairline, thick glasses, and a pronounced East Texas    accent. At first the detectives act as though they are merely    seeking information about Edwardss murder. Foreman says he    vaguely remembers her being a bridesmaid at his wedding but    denies having any other contact with her or even knowing that    she is dead. Only after being told that his semen had been    found in her body does Foreman stop talking and ask to see a    lawyer.  <\/p>\n<p>    Aaron and Bess allowed Foreman to leave the interrogation room    unimpeded. On his way out of the station, he was stopped and    handcuffed by police officers. Foreman may have recognized the    handcuffs. They had been sitting in an evidence room for nearly    three decades, until Aaron and Bess received special approval    to take them to Ohio. They were the same pair that had been    found on Edwards in 1995.  <\/p>\n<p>    After a three-year delay caused in part by the COVID-19    pandemic, the Clayton Foreman trial began on March 11 in    downtown Beaumont. The visitors gallery was packed. Foreman sat    calmly beside his attorney at the defense table, wearing an    inscrutable expression. He had pleaded not guilty; if    convicted, he would face a mandatory life sentence. Prosecutors    decided not to seek the death penalty.  <\/p>\n<p>    One of the first witnesses was Allison Brocato, now sixty years    old with shoulder-length hair and matronly glasses. She spoke    about her closeness with her twin sister, noting that she and    her husband named their second daughter Catherine. After the    murder, she said, the family was never the same. I think my    parents died a little bit, too, when she did, Brocato told the    jury, through tears. Neither lived to see the arrest of their    daughters killer.  <\/p>\n<p>    The prosecution also called Foremans former wife, Dianna Coe,    who testified that she had learned about Foremans rape charge    just three weeks before their wedding. When she confronted him,    he claimed that the arrest was a big misunderstanding, and    that the charges had been dropped. Coe, who was nineteen and    had been dating Foreman for three years, decided to go ahead    with the wedding. In 1984 she and Foreman had a son, who later    attended Price Elementary while Edwards was teaching there.  <\/p>\n<p>    One day Foreman confessed to his wife that in high school he    felt protective of Edwards and Brocato. He thought they were    so cute because they were twins, Coe testified. I didnt    think anything of it at the time. Sometime around 1987, Coe    discovered a briefcase in the trunk of Foremans car. Inside it    was a gun, a pair of handcuffs, and pornographic material. The    couple divorced in 1993. Years later, when Coe learned that    Edwards had been murdered, she called her ex-husband to tell    him the news. He had no feeling whatsoever, she recalled. It    dumbfounded me.  <\/p>\n<p>    David Mittelman took the stand on the third day of the trial.    Wearing a white shirt and blue blazer, with a relatively    clean-shaven face and hair that looked recently barbered, he    patiently walked the jury through Othrams role in the Edwards    case. Although the labs work has been used to convict dozens    of murderers, this was Mittelmans first time to testify before    a jury. He explained that Othram had found more than half a    million genetic markers in the crime scene DNA, far in excess    of what is necessary to produce a workable profile.  <\/p>\n<p>    After seven days of testimony, the case went to the jury. It    had taken nearly three decades to identify a suspect in the    murder of Catherine Edwards, but it took the jury less than an    hour to find Foreman guilty. He received an automatic life    sentence and will be eligible for parole in thirty years, when    he is 93. After the trial, one of the jurors gave an interview to a Beaumont TV station. He said    it was the DNA evidence that convinced the jury of Foremans    guilt: You cant deny that.  <\/p>\n<p>    In the wake of the verdict, Mittelman expressed pride in having    helped to resolve the three-decade-long investigation.    Unsolved cases take an immense toll on families, he told me.    Knowing that our technology has played even the smallest role    in bringing both answers and then justice is profoundly    moving.  <\/p>\n<p>    The future is already here, novelist William Gibson once    observed. Its just not very evenly distributed. David and    Kristen Mittelman believe that forensic genetic genealogy will    one day become as commonplace as fingerprint analysis. For now,    this investigative tool still suffers technical limitations,    including the relatively homogeneous geographical origin of the    DNA profiles on GEDmatch and FamilyTreeDNA, most of which come    from Australia, Europe, and North America. The majority of    forensic genetic genealogy teams are located in the United    States.  <\/p>\n<p>    Considerable need exists for this technology. As crime spiked    around the country during the COVID-19 pandemic, law    enforcement agencies were tasked with investigating a tide of    new offensesmore than one million violent crimes a year in the    U.S.with a steady or shrinking number of officers. Every crime    that isnt solved adds to the growing number of cold cases. In    addition to hundreds of thousands of unsolved murders in the    U.S., there are countless rape kits sitting in evidence rooms    nationwide. For a variety of reasons, including insufficient    funding, many have not received any kind of DNA testing.  <\/p>\n<p>    Even when a kit does get tested, nearly always for the standard    twenty genetic markers in a DNA fingerprint, it often doesnt    match any of the profiles in the FBIs Combined DNA Index    System. In those cases, police must either wait for the rapist    to strike againleaving DNA at another crime sceneor pay for    forensic genetic genealogy. Although costs are coming down, the    method still runs about $10,000 per case, in addition to the    expense of hiring a skilled genealogist. America spends more    than $100 billion every year on law enforcement, but little of    that is earmarked for forensic genetic genealogy. The amount    of money it costs to investigate a case using traditional    methods is absurd, David said. And the vast majority of it    goes to salaries.  <\/p>\n<p>    Thats why Othram sees government support as essential. Only    Congress has the resources to fund genetic genealogy work at    scale, and only Congress has the power to encourage local    police departments to make use of itperhaps by threatening to    withhold federal grants. (In the eighties, the federal    government compelled states to raise the drinking age to 21 by    indicating it would hold highway funding hostage.) But to be    eligible for such funding, genetic genealogy will likely need    to emerge from its Wild West era and embrace regulation. David    and Kristen told me that Othram would welcome such a change.    For a technology to be successful, it has to be predictable,    Kristen said. Thats how medical testing works. Thats how    almost everything works that is funded by the government.  <\/p>\n<p>    Like many start-up founders, David balances his frustration at    present circumstances with a supreme confidence about whats    yet to come. He predicted that the technology pioneered at his    modest lab in The Woodlands will one day become standard in    police departments throughout the world. There was a    sentiment, especially in the early years, that cases like    Catherine Edwardss were remarkable one-off successesthings    that are extraordinary, he told me. Were trying to go from    the extraordinary to the ordinary.   <\/p>\n<p>    This article originally appeared in the August 2024 issue    ofTexas Monthlywith the headline Decoding    a Killers DNA.Subscribe    today.  <\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Link:<br \/>\n<a target=\"_blank\" href=\"https:\/\/www.texasmonthly.com\/news-politics\/othram-forensic-genetic-genealogy-catherine-edwards-murder\/\" title=\"Inside the Texas Crime Lab Thats Cracked Hundreds of Cold Cases - Texas Monthly\" rel=\"noopener\">Inside the Texas Crime Lab Thats Cracked Hundreds of Cold Cases - Texas Monthly<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Allison Brocato last saw her sister alive on the afternoon of January 13, 1995. It was a Friday, and Catherine Edwards, Allisons 31-year-old identical twin, had just gotten off work at Price Elementary School, in Beaumont.  <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/dna\/inside-the-texas-crime-lab-thats-cracked-hundreds-of-cold-cases-texas-monthly\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-1127182","post","type-post","status-publish","format-standard","hentry","category-dna"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1127182"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=1127182"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1127182\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=1127182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=1127182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=1127182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}