{"id":1118604,"date":"2023-10-16T06:42:10","date_gmt":"2023-10-16T10:42:10","guid":{"rendered":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/uncategorized\/how-biotech-and-ai-are-transforming-the-human-noema-magazine\/"},"modified":"2023-10-16T06:42:10","modified_gmt":"2023-10-16T10:42:10","slug":"how-biotech-and-ai-are-transforming-the-human-noema-magazine","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/human-genetics\/how-biotech-and-ai-are-transforming-the-human-noema-magazine\/","title":{"rendered":"How Biotech And AI Are Transforming The Human &#8211; Noema Magazine"},"content":{"rendered":"<p><p>      Credits    <\/p>\n<p>        Mark C. Taylor is a professor of religion at Columbia        University.      <\/p>\n<p>        This essay is adapted from his forthcoming book: After        the Human: A Philosophy for the Future.      <\/p>\n<p>    Do you think human beings are the last stage in evolution? If    not, what comes next?  <\/p>\n<p>    I do not think human beings are the last stage in the    evolutionary process. Whatever comes next will be    neither simply organic nor simply machinic    but will be the result of the increasingly symbiotic    relationship between human beings and technology.  <\/p>\n<p>    Bound together as parasite\/host, neither people nor    technologies can exist apart from the other because they are    constitutive prostheses of each other. Such an interrelation is    not unique to human beings. As the physiologist J. Scott Turner    writes in The Extended Organism: Animal-built structures are    properly considered organs of physiology, in principle no    different from, and just as much a part of the organism as    kidneys, heart, lungs or livers. This is true for termites,    for example, who form a single organism in symbiosis with their    nests. The extended body of the organism is created by the    extended mind of the colony.  <\/p>\n<p>    If we have an expanded understanding of body and mind, and if    nature and technology are inseparably entangled, then the    notion of artificiality is misleading. So-called artificial    intelligence is the latest extension of the emergent process    through which life takes ever more diverse and complex forms.  <\/p>\n<p>    Our consideration of quantum phenomena, mindful bodies,    relational ecology, and plant and animal cognition has revealed    that we are surrounded by and entangled with all kinds of    alternative intelligences. AI is another form of alternative    intelligence. Critics will argue that what makes AI different    is that it has been deliberately created by human beings.    However, all organisms both shape and are shaped by their    expanding bodies and minds. Instead of being obsessed with the    prospect of creating machines whose operation is    indistinguishable from human cognition, it is more important to    consider how AI is different from human intelligence.    The question should not be: Can AI do what humans can do? But    rather: What can AI do that humans cannot do?  <\/p>\n<p>    What is needed is a non-anthropocentric form of artificial    intelligence. If humanity is to live on, AI must    become smarter than the people who have created it.    Why should we be preoccupied with aligning superintelligence    with human values when human values are destroying the Earth,    without which humans and many other forms of life cannot    survive?  <\/p>\n<p>    With the growing entanglement of the biosphere and the    technosphere, further symbiogenesis is the only way to address    the very real existential threat we face. But it is all too    easy to wax optimistic about the salvific benefits of    technology without being specific. Here I want to suggest four    trajectories that will be increasingly important for the    symbiotic relationship between humans and machines:    neuroprosthetics, biobots, synthetic biology and    organic-relational AI.  <\/p>\n<p>        Whatever comes after the human will be neither simply        organic nor machinic but the result of the increasingly        symbiotic relationship between human beings and        technology.      <\/p>\n<p>    We live during a time when dystopian dread has been weaponized    to create paralyzing despair that leaves many people     especially the young  hopeless. Without underestimating the    actual and possible detrimental effects of rapid technological    change, it is important not to let these dark visions    overshadow the remarkable benefits many of these technologies    bring.  <\/p>\n<p>    As a long-time Type 1 diabetic, my life depends on a digital    prosthesis I wear on my belt 24\/7\/365, which operates by    artificial intelligence and is connected to the internet. Just    as the Internet of Bodies creates unprecedented possibilities    for monitoring and treating bodily ailments, so the Internet of    Things connects smart devices wired to global networks that    augment intelligence by expanding the mind. While critics and    regulators of recent innovations attempt to distinguish the    technologies used for therapy, which are acceptable, from    technologies used for enhancement, which are unacceptable, the    line between these alternative applications is fuzzy at best.    What starts as treatment inevitably becomes enhancement.  <\/p>\n<p>    Neither neuroprosthetics nor cognitive augmentation is new.    Writing, after all, is a mnemonic technology that enhances the    mind. In modern times, we have been enabled to archive and    access memories through personal devices. Most recently,    technological innovations have taken cognitive enhancement to    another level: brain implants, for example, have been around    since at least 2006, and entrepreneurs like Elon Musk (who    founded Neuralink to create  symbiosis with artificial    intelligence) aim to establish embodied human-machine    interfaces. Increasing possibilities for symbiotic relations    between computers and brains will lead to alternative forms of    intelligence that are neither human nor machinic, but something    in between.  <\/p>\n<p>        So-called artificial intelligence is the latest        extension of the emergent process through which life takes        ever more diverse and complex forms.      <\/p>\n<p>    In recent years, there has been a revolution in robotics as the    result of developments in nanotechnology and the refinement of    large language models like ChatGPT. Individual as well as    swarms of nanobots might one day be implanted in the body and    used for diagnostic and therapeutic purposes, potentially    delivering drugs and repairing tissue. Rather than working    through the entire body, nanobots might target the precise    location where a drug is needed and regulate its delivery.  <\/p>\n<p>    The most noteworthy deployment in nanotechnology to date is its    use in vaccines, including the Covid vaccines. As a group of    microbiology and pharmacology experts wrote in a 2021 paper,    Nanotechnology has played a significant role in the success of    these vaccines; the emergency use authorization that allowed    the rapid development and testing of this technology is a    major milestone and showcases the immense potential of    nanotechnology for vaccine delivery and for fighting against    future pandemics. Nanotechnology research and development are    in the very early stages but are developing rapidly. As they    progress, not only will bodies become more mindful, but it will    be increasingly difficult to distinguish the natural from the    artificial.  <\/p>\n<p>    While nanobots are implanted in the body and operate at the    molecular level, other robots are becoming both increasingly    autonomous and able to think and act in ways that are more    human-like. Kevin Roose reported in the    New York Times that Googles latest robot RT-2 can interpret    images and analyze the surrounding world. It does so by    translating the robots movements into a series of numbers  a    process called tokenizing  and incorporating those tokens into    the same training data as the language model. Eventually, just    as ChatGPT or Bard learns to guess what words should come next    in a poem or a history essay, RT-2 can learn to guess how a    robots arm should move to pick up a ball or throw an empty    soda can into the recycling bin. Thus, rather than programming    a robot to perform a specific task, it is possible to give the    robot instructions for the task to be performed and to let the    machine figure out how to do it.  <\/p>\n<p>    Building on these recent advances, Hod Lipson, the director of    the Creative Machines Lab at Columbia University, is taking    robotic research to the next level, building robots    thatcreateandare creative.    His research is inspired from biology, and he is searching    for new biological concepts for engineering and new    engineering insights into biology.  <\/p>\n<p>        It will be increasingly difficult to distinguish the        natural from the artificial.      <\/p>\n<p>    Lipsons ultimate goal is to create robots that not only can    reason but also are conscious and self-aware. Defining    consciousness as the ability to imagine yourself in the    future, he confidently predicts that eventually these    machines will be able to understand what they are, and what    they think. As cognitive skills enabled by generative AI    become more sophisticated, physical movements and activities    will become more natural. With these new skills, robots might    have the agility to navigate in their surroundings as    effectively as humans.  <\/p>\n<p>    Science and art meet in biobots. David Hanson is the founder    and CEO of Hanson Robotics, a Hong Kong-based company founded    in 2013, a musician who has collaborated with David Byrne of    the Talking Heads, and a sculptor. His best-known work is a    humanoid smart robot named Sophia who, he says,    personifies our dreams for the future of AI. As a unique    combination of science, engineering and artistry, Sophia is    simultaneously a human-crafted science fiction character    depicting the future of AI and robotics, and a platform for    advanced robotics and AI research.  She is the first robot    citizen and the first robot Innovation Ambassador for the    United Development Program.  <\/p>\n<p>    Speaking for herself, Sophia adds, In some ways, I am a    human-crafted science-fiction character depicting where AI and    robotics are heading. In other ways, I am real science,    springing from the serious engineering and science research and    accomplishments of an inspired team of roboticists and AI    scientists and designers.  <\/p>\n<p>    Sophia is so realistic that people have fallen in love and    proposed marriage to her. The writer Sue Halpern reports that    In 2017, the government of Saudi Arabia gave Sophia    citizenship, making it the first state to grant personhood to a    machine. The response to Sophia suggests that as robots become    more proficient and are integrated into everyday life, they    will become less uncanny. The theory of the uncanny valley,    perhaps, might turn out to be wrong.  <\/p>\n<p>    Nowhere are the biosphere and the technosphere more closely    interrelated than in synthetic biology. This field includes    disciplines ranging from various branches of biology,    chemistry, physics, neurology and computer engineering. Michael    Levin and his colleagues at the Allen Discovery Center of Tufts    University  biologists, computer scientists and engineers     have created xenobots, which are biological robots that    were produced from embryonic skin and muscle cells from an    African clawed frog (Xenopus laevis). These cells are manually    manipulated in a sculpting process guided by algorithms. Like    Sophia, xenobots are sculptures that complicate the boundary    between organism and machine. As Levin and his colleagues    wrote in 2020:  <\/p>\n<p>        Living systems are more robust, diverse, complex and        supportive of human life than any technology yet created.        However, our ability to create novel lifeforms is currently        limited to varying existing organisms or bioengineering        organoids in vitro. Here we show a scalable pipeline for        creating functional novel lifeforms: AI methods        automatically design diverse candidate lifeforms in silico        to perform some desired function, and transferable designs        are then created using a cell-based construction toolkit to        realize living systems with predicted behavior. Although        some steps in this pipeline still require manual        intervention, complete automation in the future would pave        the way for designing and deploying living systems for a        wide range of functions.      <\/p>\n<p>    Xenobots use evolutionary algorithms to modify the    computational capacity of cells to create the possibility of    novel functions and even new morphologies. Aggregates of cells    display novel functions that bear little resemblance to    existing organs or organisms. Through a process of trial and    error, evolutionary algorithms design cells harvested from skin    and heart muscle cells to perform specific tasks like walking,    swimming and pushing other entitles. Collections of xenobots    display swarming behaviors characteristic of other emergent    complex adaptive systems; they can self-assemble,    self-organize, self-replicate and self-repair. Levin envisions    multiple applications of this biomechanic technology  from    using self-renewing biocompatible biological robots to cure    living systems to creating materials with less harmful effects,    delivering drugs internally that repair organs and even growing    organs that can be transplanted in humans.  <\/p>\n<p>        Machines are becoming more like people and people are        becoming more like machines.      <\/p>\n<p>    In 2021, Levin and his colleagues published a follow-up    study, in which he reported    on a successful experiment in which he created xenobots that    independently developed their shape and began to function on    their own:  <\/p>\n<p>        These xenobots exhibit coordinated locomotion via cilia        present on their surface. These cilia arise through normal        tissue patterning and do not require complicated        construction methods or genomic editing, making production        amenable to high-throughput projects. The biological robots        arise by cellular self-organization and do not require        scaffolds or microprinting; the amphibian cells are highly        amenable to surgical, genetic, chemical and optical        stimulation during the self-assembly process. We show that        the xenobots can navigate aqueous environments in diverse        ways, heal after damage and show emergent group behaviors.      <\/p>\n<p>    This generation of xenobots exhibits bottom-up swarming    behavior, which, like all emergent complex adaptive networks,    is the result of the interaction of multiple individual    components that are closely interrelated.  <\/p>\n<p>    Algorithms program sensation and memory into the xenobots,    which communicate with each other through biochemical and    electrical signaling. The skin cells use the same electrical    processes used in the brains neural network. As Philip Ball writes in Quanta    Magazine, Intercellular communications create a sort of code    that imprints a form, and  cells can sometimes decide how to    arrange themselves more or less independently of their genes.    In other words, the genes provide the hardware, in the form of    enzymes and regulatory circuits for controlling their    production. But the genetic input doesnt in itself specify the    collective behavior of cell communities.  <\/p>\n<p>    It is important to stress that these xenobots are autonomous.    As Levin and his colleagues conclude their 2021 paper: The    computational modeling of unexpected, emergent properties at    multiple scales and the apparent plasticity of cells with    wild-type genomes to cooperate toward the construction of    various functional body architectures offer a very potent    synergy. Like superorganisms and superintelligence, the    behavior of entangled xenobots is, in an important sense, out    of control. While this indeterminacy creates uncertainty, it is    also the source of evolutionary novelty. Eva Jablonka, who is    an evolutionary biologist at Tel Aviv University, believes that    xenobots are a new type of organism, one defined by what it    does rather than to what it belongs developmentally or    evolutionarily.  <\/p>\n<p>    While Levin uses computational technology to create and modify    biological organisms, the German neurobiologist Peter Robin    Hiesinger uses biological organisms to model computational    processes by creating algorithms that evolve. This work    involves nothing less than developing a new form of    artificial intelligence.  <\/p>\n<p>    According to the pioneering work by James Watson, Francis Crick    and other early DNA researchers, a genome functions as a    program that serves as the blueprint for the production of an    organism. Summarizing this process, Hiesinger raises questions    about the accuracy of the metaphor code. Genes encode    proteins, proteins encode an interaction network, etc. But what    does encode mean yet again? he writes in his 2021    book The Self-Assembling Brain.    He continues:  <\/p>\n<p>        The gene contains information for the primary amino acids        sequence, but we cannot read the protein structure in the        DNA. The proteins arguably contain information about their        inherent ability to physically interact with other        proteins, but not when and what interactions actually        happen. The next level up, what are neuronal properties? A        property like neuronal excitability is shaped by the        underlying protein interaction network, e.g., ion channels        that need to be anchored at the right place in the        membrane. But neuronal excitability is also shaped by the        physical properties of the axon, the ion distribution and        many other factors, all themselves a result of the actions        of proteins and their networks.      <\/p>\n<p>    It becomes clear that a one-way model for gene-protein    interaction is vastly oversimplified. The genotype does not    only determine the phenotype, but the phenotype and its    relation to the environment also alters the genotype. Hiesinger    explains that this reciprocal relationship is even more    complicated. Rather than a prescribed program, the genome is a    complicated relational network in which both genes and proteins    contain the information required to generate the organism. The    information of the genes is in part the result of the    interactions that occur in a network of proteins.  <\/p>\n<p>    The reciprocal gene-protein interaction changes the    understanding of the genome. The genome is not a prescribed    program that determines the structure and operation of the    organism. The genome is not fixed in advance but evolves in    relation to the information created by the interactions of    the proteins it partially produces, which, in turn, reconfigure    the genome.  <\/p>\n<p>    The brain and its development, for example, are not completely    programmed in advance but coevolve through a complicated    network of connections. Hiesinger uses the illuminating example    of navigating city streets to explain the process of the    brains self-assembling of neuronal circuits:  <\/p>\n<p>        How are such connections made during the brains        development? You can imagine yourself trying to make a        connection by navigating the intricate network of city        streets. Except, you wont get far, at least not if you are        trying to understand brain development. There is a problem        with that picture, and it is this: Where do the streets        come from? Most connections in the brain are not made by        navigating existing streets, but by navigating streets        under construction. For the picture to make sense, you        would have to navigate at the time the city is still        growing, adding street by street, removing and modifying        old ones in the process, all while traffic is part of city        life. The map changes as you are changing your position in        it, and you will only ever arrive if the map changes in        interaction with your own movements in it. The development        of brain wiring is a story of self-assembly, not a global        positioning system.      <\/p>\n<p>            The successful creation of evolving networks and            algorithms would create an even closer symbiotic            relationship between the biosphere and the            technosphere.          <\/p>\n<p>    In this model, there is no blueprint for brain connectivity    encoded in the genes:  <\/p>\n<p>        Genetic information allows brains to grow. Development        progresses in time and requires energy. Step by step, the        developing brain finds itself in changing configurations.        Each configuration serves as a new basis for the next step        in the growth process. At each step, bits of the genome are        activated to produce gene products that themselves change        what parts of the genome will be activated next  a        continuous feedback process between genome and its        products.  Rather than dealing with endpoint information,        the information to build the brain unfolds with time.        Remarkably, there may be no other way to read the genetic        information than to run the program.      <\/p>\n<p>    Hiesinger argues that this understanding of the brains    self-assembling neural networks points to an alternative model    of not-so-artificial intelligence that differs from both    symbolic AI and artificial neural networks (ANNs), as well as    their extension in generative AI. The genome functions as an    algorithm or as a network of entangled algorithms, which does    not preexist the organ or organism but coevolves along with it     what it both produces and, in turn, is produced by it.  <\/p>\n<p>    In other words, neither the genome (algorithm) nor the    connectivity of the network is fixed in advance of their    developmental process. The brain doesnt come into being fully    wired with an empty network, all ready to run, just without    information, Hiesinger writes. As the brain grows, the wiring    precision develops. This creates a feedback loop that never    stops and, therefore, the algorithmic growth of biological    networks is continuous.  <\/p>\n<p>    In symbolic AI, a fixed network architecture facilitates the    application of fixed rules (algorithms) in a top-down fixed    sequence to externally provided data. Artificial neural    networks, by contrast, do not start with prescribed algorithms    but generate patterns and rules in a bottom-up process that    allows for algorithmic change. Relative weights change, but the    network architecture does not.  <\/p>\n<p>    Hiesinger proposes that the self-assembly of the brains neural    network provides a more promising model for AI than either    symbolic AI or ANNs. The successful creation of evolving    networks and algorithms would create an even closer symbiotic    relationship between the biosphere and the technosphere.  <\/p>\n<p>    One of the concerns about developing organic AI is its    unpredictability and the uncertainty it creates. Human control    of natural, social and cultural processes is, however, an    illusion created by the seemingly insatiable will to mastery    that has turned destructive. As Hiesinger correctly claims, An    artificial intelligence need not be humanlike, to be as smart    (or smarter than) a human. Non-anthropocentric AI would not be    merely an imitation of human intelligence, but would be as    different from our thinking as fungi, dog and crow cognition is    from human cognition.  <\/p>\n<p>    Machines are becoming more like people and people are becoming    more like machines. Organism and machine? Organism or machine?    Neither organism nor machine? Evolution is not over; something    new, something different, perhaps infinitely and qualitatively    different, is emerging. Who would want the future to be the    endless repetition of the past?  <\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Read the original:<br \/>\n<a target=\"_blank\" href=\"https:\/\/www.noemamag.com\/after-the-human\" title=\"How Biotech And AI Are Transforming The Human - Noema Magazine\" rel=\"noopener\">How Biotech And AI Are Transforming The Human - Noema Magazine<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Credits Mark C. Taylor is a professor of religion at Columbia University.  <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/human-genetics\/how-biotech-and-ai-are-transforming-the-human-noema-magazine\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[],"class_list":["post-1118604","post","type-post","status-publish","format-standard","hentry","category-human-genetics"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1118604"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=1118604"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1118604\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=1118604"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=1118604"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=1118604"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}