{"id":1090498,"date":"2022-10-02T16:42:37","date_gmt":"2022-10-02T20:42:37","guid":{"rendered":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/uncategorized\/stroke-genetics-informs-drug-discovery-and-risk-prediction-across-ancestries-nature-com\/"},"modified":"2022-10-02T16:42:37","modified_gmt":"2022-10-02T20:42:37","slug":"stroke-genetics-informs-drug-discovery-and-risk-prediction-across-ancestries-nature-com","status":"publish","type":"post","link":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/genome\/stroke-genetics-informs-drug-discovery-and-risk-prediction-across-ancestries-nature-com\/","title":{"rendered":"Stroke genetics informs drug discovery and risk prediction across ancestries &#8211; Nature.com"},"content":{"rendered":"<p><p>Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France<\/p>\n<p>Aniket Mishra,Quentin Le Grand,Ilana Caro,Constance Bordes,David-Alexandre Trgout,Marine Germain,Christophe Tzourio,Jean-Franois Dartigues,Sara Kaffashian,Quentin Le Grand,Florence Saillour-Glenisson&Stephanie Debette<\/p>\n<p>Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany<\/p>\n<p>Rainer Malik,Marios K. Georgakis,Steffen Tiedt&Martin Dichgans<\/p>\n<p>Iwate Tohoku Medical Megabank Organization, Iwate Medical University, Iwate, Japan<\/p>\n<p>Tsuyoshi Hachiya,Makoto Sasaki,Atsushi Shimizu,Yoichi Sutoh,Kozo Tanno&Kenji Sobue<\/p>\n<p>Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia<\/p>\n<p>Tuuli Jrgenson,Kristi Krebs,Kaido Lepik,Tnu Esko,Andres Metspalu,Reedik Mgi,Mari Nelis&Lili Milani<\/p>\n<p>Institute of Mathematics and Statistics, University of Tartu, Tartu, Estonia<\/p>\n<p>Tuuli Jrgenson<\/p>\n<p>Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan<\/p>\n<p>Shinichi Namba,Takahiro Konuma&Yukinori Okada<\/p>\n<p>Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, MA, USA<\/p>\n<p>Daniel C. Posner,Kelly Cho,Yuk-Lam Ho&Jennifer E. Huffman<\/p>\n<p>TIMI Study Group, Boston, MA, USA<\/p>\n<p>Frederick K. Kamanu,Nicholas A. Marston,Marc S. Sabatine&Christian T. Ruff<\/p>\n<p>Division of Cardiovascular Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA<\/p>\n<p>Frederick K. Kamanu,Nicholas A. Marston,Marc S. Sabatine&Christian T. Ruff<\/p>\n<p>Division of Molecular Pathology, Institute of Medical Sciences, The University of Tokyo, Tokyo, Japan<\/p>\n<p>Masaru Koido,Takayuki Morisaki&Yoishinori Murakami<\/p>\n<p>Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan<\/p>\n<p>Masaru Koido,Mingyang Shi,Yunye He&Yoichiro Kamatani<\/p>\n<p>Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA<\/p>\n<p>Marios K. Georgakis,Livia Parodi,Jonathan Rosand,Christopher D. Anderson,Ernst Mayerhofer&Christopher D. Anderson<\/p>\n<p>Program in Medical and Population Genetics, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA<\/p>\n<p>Marios K. Georgakis,Livia Parodi,Phil L. de Jager,Jonathan Rosand,Christopher D. Anderson,Guido J. Falcone,Phil L. de Jager,Ernst Mayerhofer&Christopher D. Anderson<\/p>\n<p>Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan<\/p>\n<p>Yi-Ching Liaw&Koichi Matsuda<\/p>\n<p>Department of Public Health and Institute of Public Health, Chung Shan Medical University, Taichung, Taiwan<\/p>\n<p>Yi-Ching Liaw,Pei-Hsin Chen&Yung-Po Liaw<\/p>\n<p>Department of Internal Medicine, University of Turku, Turku, Finland<\/p>\n<p>Felix C. Vaura&Teemu J. Niiranen<\/p>\n<p>Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Turku, Finland<\/p>\n<p>Felix C. Vaura&Teemu J. Niiranen<\/p>\n<p>Nuffield Department of Population Health, University of Oxford, Oxford, UK<\/p>\n<p>Kuang Lin,Zhengming Chen,Cornelia M. van Duijn,Robert Clarke,Rory Collins,Richard Peto,Yiping Chen,Zammy Fairhurst-Hunter,Michael Hill,Alfred Pozarickij,Dan Schmidt,Becky Stevens,Iain Turnbull,Iona Y. Millwood,Keum Ji Jung&Robin G. Walters<\/p>\n<p>Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway<\/p>\n<p>Bendik Slagsvold Winsvold,Ingrid Heuch,Linda M. Pedersen,Amy E. Martinsen,Espen S. Kristoffersen&John-Anker Zwart<\/p>\n<p>K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway<\/p>\n<p>Bendik Slagsvold Winsvold,Sigrid Brte,Kristian Hveem,Ben M. Brumpton,Jonas B. Nielsen,Maiken E. Gabrielsen,Anne H. Skogholt,Ben M. Brumpton,Maiken E. Gabrielsen,Amy E. Martinsen,Jonas B. Nielsen,Kristian Hveem,Laurent F. Thomas&John-Anker Zwart<\/p>\n<p>Department of Neurology, Oslo University Hospital, Oslo, Norway<\/p>\n<p>Bendik Slagsvold Winsvold&Anne H. Aamodt<\/p>\n<p>Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA<\/p>\n<p>Vinodh Srinivasasainagendra,Hemant K. Tiwari&George Howard<\/p>\n<p>Department of Neurology and Cerebrovascular Disease Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea<\/p>\n<p>Hee-Joon Bae<\/p>\n<p>Rajendra Institute of Medical Sciences, Ranchi, India<\/p>\n<p>Ganesh Chauhan,Amit Kumar&Kameshwar Prasad<\/p>\n<p>Thrombosis and Atherosclerosis Research Institute, David Braley Cardiac, Vascular and Stroke Research Institute, Hamilton, Ontario, Canada<\/p>\n<p>Michael R. Chong&Guillaume Par<\/p>\n<p>Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada<\/p>\n<p>Michael R. Chong&Guillaume Par<\/p>\n<p>Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland<\/p>\n<p>Liisa Tomppo,Jukka Putaala,Gerli Sibolt,Nicolas Martinez-Majander,Sami Curtze,Marjaana Tiainen,Janne Kinnunen&Daniel Strbian<\/p>\n<p>Center for Genomic and Precision Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria<\/p>\n<p>Rufus Akinyemi,Abiodun M. Adeoye&Mayowa O. Owolabi<\/p>\n<p>Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria<\/p>\n<p>Rufus Akinyemi<\/p>\n<p>Department of Epidemiology, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands<\/p>\n<p>Gennady V. Roshchupkin,Maria J. Knol,Cornelia M. van Duijn,Najaf Amin,Sven J. van der Lee,Mohsen Ghanbari,Mohammad K. Ikram&Mohammad A. Ikram<\/p>\n<p>Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands<\/p>\n<p>Gennady V. Roshchupkin<\/p>\n<p>The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel<\/p>\n<p>Naomi Habib&Anael Cain<\/p>\n<p>Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA<\/p>\n<p>Yon Ho Jee<\/p>\n<p>Department of Clinical Biochemistry, Copenhagen University HospitalRigshospitalet, Copenhagen, Denmark<\/p>\n<p>Jesper Qvist Thomassen,Anne Tybjrg-Hansen,Marianne Benn&Ruth Frikke-Schmidt<\/p>\n<p>Department of Molecular and Functional Genomics, Weis Center for Research, Geisinger Health System, Danville, VA, USA<\/p>\n<p>Vida Abedi&Jiang Li<\/p>\n<p>Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, State College, PA, USA<\/p>\n<p>Vida Abedi<\/p>\n<p>Stroke Pharmacogenomics and Genetics Laboratory, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain<\/p>\n<p>Jara Crcel-Mrquez,Nuria P. Torres-Aguila,Natalia Cullell,Elena Muio,Cristina Gallego-Fabrega,Miquel Lleds,Laia Lluci-Carol&Israel Fernndez-Cadenas<\/p>\n<p>Departament de Medicina, Universitat Autnoma de Barcelona, Barcelona, Spain<\/p>\n<p>Jara Crcel-Mrquez<\/p>\n<p>The Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark<\/p>\n<p>Marianne Nygaard&Kaare Christensen<\/p>\n<p>Department of Clinical Genetics, Odense University Hospital, Odense, Denmark<\/p>\n<p>Marianne Nygaard&Kaare Christensen<\/p>\n<p>Center for Alzheimers and Related Dementias, National Institutes of Health, Bethesda, MD, USA<\/p>\n<p>Hampton L. Leonard&Mike A. Nalls<\/p>\n<p>Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA<\/p>\n<p>Hampton L. Leonard&Mike A. Nalls<\/p>\n<p>Data Tecnica International, Glen Echo, MD, USA<\/p>\n<p>Hampton L. Leonard&Mike A. Nalls<\/p>\n<p>Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA<\/p>\n<p>Chaojie Yang,Ani Manichaikul,Stephen S. Rich,Wei Min Chen,Michle M. Sale&Wei-Min Chen<\/p>\n<p>Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA<\/p>\n<p>Chaojie Yang<\/p>\n<p>British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK<\/p>\n<p>Ekaterina Yonova-Doing,Michael Inouye&Joanna M. M. Howson<\/p>\n<p>Department of Genetics, Novo Nordisk Research Centre Oxford, Oxford, UK<\/p>\n<p>Ekaterina Yonova-Doing&Joanna M. M. Howson<\/p>\n<p>Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA<\/p>\n<p>Adam J. Lewis,Jing He,Seung Hoan Choi&Lisa Bastarache<\/p>\n<p>Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA<\/p>\n<p>Renae L. Judy<\/p>\n<p>Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan<\/p>\n<p>Tetsuro Ago&Takanari Kitazono<\/p>\n<p><!-- Auto Generated --><\/p>\n<p>Go here to read the rest:<br \/>\n<a target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41586-022-05165-3\" title=\"Stroke genetics informs drug discovery and risk prediction across ancestries - Nature.com\" rel=\"noopener\">Stroke genetics informs drug discovery and risk prediction across ancestries - Nature.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Bordeaux Population Health Research Center, University of Bordeaux, Inserm, UMR 1219, Bordeaux, France Aniket Mishra,Quentin Le Grand,Ilana Caro,Constance Bordes,David-Alexandre Trgout,Marine Germain,Christophe Tzourio,Jean-Franois Dartigues,Sara Kaffashian,Quentin Le Grand,Florence Saillour-Glenisson&#038;Stephanie Debette Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany Rainer Malik,Marios K.  <a href=\"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/transhuman-news-blog\/genome\/stroke-genetics-informs-drug-discovery-and-risk-prediction-across-ancestries-nature-com\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-1090498","post","type-post","status-publish","format-standard","hentry","category-genome"],"_links":{"self":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1090498"}],"collection":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/comments?post=1090498"}],"version-history":[{"count":0,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/posts\/1090498\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/media?parent=1090498"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/categories?post=1090498"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.euvolution.com\/prometheism-transhumanism-posthumanism\/wp-json\/wp\/v2\/tags?post=1090498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}