Zhang, L. F. Region-specific vascular remodeling and its prevention by artificial gravity in weightless environment. Eur. J. Appl. Physiol. 113, 28732895 (2013).<\/p>\n
PubMed Article ADS Google Scholar <\/p>\n
Lawley, J. S. et al. Effect of gravity and microgravity on intracranial pressure. J. Physiol. 595, 21152127 (2017).<\/p>\n
MathSciNet CAS PubMed PubMed Central Article Google Scholar <\/p>\n
Chen, L. et al. BMAL1 Disrupted intrinsic diurnal oscillation in rat cerebrovascular contractility of simulated microgravity rats by altering circadian regulation of miR-103\/CaV1.2 Signal Pathway. Int. J. Mol. Sci. 20, 3947; https:\/\/doi.org\/10.3390\/ijms20163947<\/a> (2019).<\/p>\n Otsuka, K. et al. Intrinsic cardiovascular autonomic regulatory system of astronauts exposed long-term to microgravity in space: observational study. NPJ Microgravity 1, 15018; https:\/\/doi.org\/10.1038\/npjmgrav<\/a> (2015).<\/p>\n Otsuka, K. et al. Long-term exposure to spaces microgravity alters the time structure of heart rate variability of astronauts. Heliyon 2, e00211; https:\/\/doi.org\/10.1016\/j.heliyon.2016.e00211<\/a> (2016).<\/p>\n Aoyagi, N., Ohashi, K., Tomono, S. & Yamamoto, Y. Temporal contribution of body movement to very long-term heart rate variability in humans. Am. J. Physiol. Heart Circ. Physiol. 278, H1035H1041 (2000).<\/p>\n CAS PubMed Article Google Scholar <\/p>\n Aoyagi, N., Ohashi, K. & Yamamoto, Y. Frequency characteristics of long-term heart rate variability during constant-routine protocol. Am. J. Physiol. Regul. Integr. Comp. Physiol. 285, R171R176 (2003).<\/p>\n CAS PubMed Article Google Scholar <\/p>\n Le Bourg, E. A review of the effects of microgravity and of hypergravity on aging and longevity. Exp. Gerontol. 34, 319336 (1999).<\/p>\n PubMed Article Google Scholar <\/p>\n Vernikos, J. & Schneider, V. S. Space, gravity and the physiology of aging: parallel or convergent disciplines? A mini-review. Gerontology 56, 157166 (2010).<\/p>\n PubMed Article Google Scholar <\/p>\n Honda, Y. et al. Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans. Sci. Rep. 2, 487; https:\/\/doi.org\/10.1038\/srep00487<\/a> (2012).<\/p>\n Ma. L., Ma, J., & Xu, K. Effect of spaceflight on the circadian rhythm, lifespan and gene expression of Drosophila melanogaster. PLoS. One 23, 10: e0121600; https:\/\/doi.org\/10.1371\/journal.pone.0121600<\/a> (2015).<\/p>\n Garrett-Bakelman, F.E. et al. The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight. Science 364, eaau8650; https:\/\/doi.org\/10.1126\/science.aau8650<\/a> (2019).<\/p>\n Charles, J. B. & Pietrzyk, R. A. A year on the International Space Station: implementing a long-duration biomedical research mission. Aerosp. Med. Hum. Perform. 90, 411 (2019).<\/p>\n PubMed Article Google Scholar <\/p>\n Turner, K.J., Vasu, V. & Griffin, D.K. Telomere biology and human phenotype. Cells. 8, 73; https:\/\/doi.org\/10.3390\/cells8010073<\/a> (2019).<\/p>\n Lulkiewicz, M., Bajsert, J., Kopczynski, P., Barczak, W. & Rubis, B. Telomere length: how the length makes a difference. Mol. Biol. Rep. 47, 71817188 (2020).<\/p>\n CAS PubMed PubMed Central Article Google Scholar <\/p>\n Nwanaji-Enwerem, J.C. et al. A longitudinal epigenetic aging and leukocyte analysis of simulated space travel: The Mars-500 mission. Cell Rep. 33, 108406; https:\/\/doi.org\/10.1016\/j.celrep.2020.108406<\/a> (2020).<\/p>\n Otsuka. K. et al. Anti-aging effects of long-term space missions, estimated by heart rate variability. Sci. Rep. 9, 8995; https:\/\/doi.org\/10.1038\/s41598-019-45387-6<\/a> (2019).<\/p>\n Otsuka. K. et al. Astronauts well-being and possibly anti-aging improved during long-duration spaceflight. Sci Rep. 11, 14907; https:\/\/doi.org\/10.1038\/s41598-021-94478-w<\/a> (2021).<\/p>\n Otsuka. K. et al. Circadian challenge of astronauts unconscious mind adapting to microgravity in space, estimated by heart rate variability. Sci Rep. 8, 10381; org\/https:\/\/doi.org\/10.1038\/s41598-018-28740-z (2018).<\/p>\n Fernandez, L.M.J. et al. Quantifying infra-slow dynamics of spectral power and heart rate in sleeping mice.J. Vis. Exp. 126, 55863; https:\/\/doi.org\/10.3791\/55863<\/a> (2017).<\/p>\n Lecci, S. et al. Coordinated infraslow neural and cardiac oscillations mark fragility and offline periods in mammalian sleep.Sci. Adv.3, e1602026; https:\/\/doi.org\/10.1126\/sciadv.1602026<\/a> (2017).<\/p>\n Watson, B.O. Cognitive and physiologic impacts of the infraslow oscillation.Front. Syst. Neurosci. 12, 44: https:\/\/doi.org\/10.3389\/fnsys.2018.00044<\/a> (2018).<\/p>\n Okun, M., Steinmetz, N. A., Lak, A., Dervinis, M. & Harris, K. D. Distinct structure of cortical population activity on fast and infraslow timescales. Cereb. Cortex 29, 21962210 (2019).<\/p>\n PubMed PubMed Central Article Google Scholar <\/p>\n Lau, H. C. & Passingham, R. E. Unconscious activation of the cognitive control system in the human prefrontal cortex. J. Neurosci. 27, 58055811 (2007).<\/p>\n CAS PubMed PubMed Central Article Google Scholar <\/p>\n Elman, I. et al. Mechanisms Underlying unconscious processing and their alterations in post-traumatic stress disorder: neuroimaging of zero monetary outcomes contextually framed as \"no losses\" vs. \"no gains\". Front. Neurosci. 14, 604867; https:\/\/doi.org\/10.3389\/fnins.2020.604867<\/a> (2020).<\/p>\n Banaclocha, M. A. Neuromagnetic dialogue between neuronal minicolumns and astroglial network: a new approach for memory and cerebral computation. Brain Res. Bull. 73, 2127 (2007).<\/p>\n PubMed Article Google Scholar <\/p>\n Brancaccio, M., Patton, A. P., Chesham, J. E., Maywood, E. S. & Hastings, M. H. Astrocytes control circadian timekeeping in the suprachiasmatic nucleus via glutamatergic signaling. Neuron 93, 14201435 (2017).<\/p>\n CAS PubMed PubMed Central Article Google Scholar <\/p>\n Hastings, M.H., Maywood, E.S. & Brancaccio, M. The mammalian circadian timing system and the suprachiasmatic nucleus as its pacemaker. Biology (Basel) 8, 13; https:\/\/doi.org\/10.3390\/biology8010013<\/a> (2019).<\/p>\n Baevsky, R. M. Noninvasive methods in space cardiology. J. Cardiovasc. Diagn. Proced. 14, 161171 (1997).<\/p>\n CAS PubMed Google Scholar <\/p>\n Baevsky, R. M., Petrov, V. M. & Chernikova, A. G. Regulation of autonomic nervous system in space and magnetic storms. Adv. Space Res. 22, 227234 (1998).<\/p>\n CAS PubMed Article ADS Google Scholar <\/p>\n Ivanov, PCh. et al. Sleep-wake differences inscaling behavior of the human heartbeat: analysis of terrestrial and long-term space flight data. Europhys. Lett. 48, 594600 (1999).<\/p>\n CAS PubMed Article ADS Google Scholar <\/p>\n Gundel, A., Drescher, J., Spatenko, Y. A. & Polyakov, V. V. Changes in basal heart rate in spaceflights up to 438 days. Aviat. Space Environ. Med. 73, 1721 (2002).<\/p>\n PubMed Google Scholar <\/p>\n Baevski, R. M. Analysis of variability of cardiac rhythm in space medicine. Fiziol. Cheloveka 28, 7082 (2002).<\/p>\n PubMed Google Scholar <\/p>\n Norsk, P. et al. Vasorelaxation in space. Hypertension 47, 6973 (2006).<\/p>\n CAS PubMed Article Google Scholar <\/p>\n Baevsky, R. M. et al. Autonomic cardiovascular and respiratory control during prolonged spaceflights aboard the International Space Station. J. Appl. Physiol. 1985(103), 156161 (2007).<\/p>\n Article Google Scholar <\/p>\n Verheyden, B., Liu, J., Beckers, F. & Aubert, A. E. Operational point of neural cardiovascular regulation in humans up to 6 months in space. J. Appl. Physiol. 1985(108), 646654 (2010).<\/p>\n Article Google Scholar <\/p>\n Hughson, R. L. et al. Cardiovascular regulation during long-duration spaceflights to the International Space Station. J. Appl. Physiol. 1985(112), 719727 (2012).<\/p>\n Article Google Scholar <\/p>\n Xu, D., Shoemaker, J.K., Blaber, A.P., Arbeille, P., Fraser, K. & Hughson RL. Reduced heart rate variability during sleep in long-duration spaceflight. Am. J. Physiol. Regul. Integr. Comp. Physiol. 305, R164170 (2012).<\/p>\n Vandeput, S., Widjaja, D., Aubert, A. E. & Van Huffel, S. Adaptation of autonomic heart rate regulation in astronauts after spaceflight. Med. Sci. Monit. 19, 917 (2013).<\/p>\n PubMed PubMed Central Article Google Scholar <\/p>\n Norsk, P., Asmar, A., Damgaard, M. & Christensen, N. J. Fluid shifts, vasodilatation and ambulatory blood pressure reduction during long duration spaceflight. J. Physiol. 593, 573584 (2015).<\/p>\n CAS PubMed PubMed Central Article Google Scholar <\/p>\n Aubert, A. E. et al. Towards human exploration of space: the THESEUS review series on cardiovascular, respiratory, and renal research priorities. NPJ. Microgravity 2, 16031. https:\/\/doi.org\/10.1038\/npjmgrav.2016.31<\/a> (2016).<\/p>\n Article PubMed PubMed Central Google Scholar <\/p>\n Vernice, N. A., Meydan, C., Afshinnekoo, E. & Mason, C. E. Long-term spaceflight and the cardiovascular system Precis. Clin. Med. 3, 284291 (2020).<\/p>\n Google Scholar <\/p>\n Baevsky, R. M. et al. Adaptive responses of the cardiovascular system to prolonged spaceflight conditions: assessment with Holter monitoring. J. Cardiovasc. Diagn. Proced. 14, 5357 (1997).<\/p>\n CAS PubMed Google Scholar <\/p>\n Baevsky, R.M., Moser, M., Nikulina, G.A., Polyakov, V.V., Funtova, II & Chernikova, A.G. Autonomic regulation of circulation and cardiac contractility during a 14-month space flight. Acta. Astronaut. 42, 159173 (1998).<\/p>\n Baevsky, R. M., Nikulina, G. A., Funtova, I. I. & Chernikova, A. G. Vegetative regulation of blood circulation. Orbital Station MIR 2, 3668 (2001).<\/p>\n Google Scholar <\/p>\n Monk, T. H., Buysse, D. J. & Rose, L. R. Wrist actigraphic measures of sleep in space. Sleep 22, 948954 (1999).<\/p>\n CAS PubMed Google Scholar <\/p>\n Dijk, D. J. et al. Sleep, performance, circadian rhythms, and light-dark cycles during two space shuttle flights. Am. J. Physiol. Regul. Integr. Comp. Physiol. 281, R1647R1664 (2001).<\/p>\n CAS PubMed Article Google Scholar <\/p>\n Barger, L. K. et al. Prevalence of sleep deficiency and use of hypnotic drugs in astronauts before, during, and after spaceflight: an observational study. Lancet Neurol. 13, 904912 (2014).<\/p>\n PubMed PubMed Central Article Google Scholar <\/p>\n Yamamoto, N. et al. Effects of long-term microgravity exposure in space on circadian rhythms of heart rate variability. Chronobiol. Int. 32, 327340 (2015).<\/p>\n CAS PubMed Article Google Scholar <\/p>\n Task, F. of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation. 93, 10431065 (1996).<\/p>\n Saito K, Koyama A, Yoneyama K, Sawada Y, Ohtomo, N. A recent advances in time series analysis by maximum entropy method. Hokkaido University Press (Sapporo, 1994)<\/p>\n Baria, A. T., Baliki, M. N., Parrish, T. & Apkarian, A. V. Anatomical and functional assemblies of brain BOLD oscillations. J. Neurosci. 31, 79107919 (2011).<\/p>\n CAS PubMed PubMed Central Article Google Scholar <\/p>\n Bingham, C., Arbogast, B., Cornelissen, G. G., Lee, J. K. & Halberg, F. Inferential statistical methods for estimating and comparing cosinor parameters. Chronobiologia 9, 397439 (1982).<\/p>\n CAS PubMed Google Scholar <\/p>\n Cornelissen, G. Cosinor-based rhythmometry. Theor. Biol. Med. Model 11, 16; https:\/\/doi.org\/10.1186\/1742-4682-11-16<\/a> (2014).<\/p>\n Otsuka, K., Cornelissen, G. & Halberg, F. Chronomics and continuous ambulatory blood pressure monitoring Vascular chronomics: From 7-day\/24-hour to lifelong monitoring. (Tokyo: Springer Japan), pp 870 + lxxv ; https:\/\/doi.org\/10.1007\/978-4-431-54631-3<\/a> (2016).<\/p>\n Kamide, Y., Richmond, A. D. & Matsushita, S. Estimation of ionospheric electric field, ionospheric currents and field-aligned currents from ground magnetic records. J. Geophys. Res. 86, 801813 (1981).<\/p>\n Article ADS Google Scholar <\/p>\n Kamide, Y. Estimate of electromagnetic quantities in space from ground magnetic records. Science 241(4863), 328330 (1988).<\/p>\n CAS PubMed Article ADS Google Scholar <\/p>\n Kamide, Y. et al. Combining electric field and aurora observations from DE 1 and 2 with ground magnetometer records to estimate ionospheric electromagnetic quantities. J. Geophys. Res. 94, 67236738 (1989).<\/p>\n Article ADS Google Scholar <\/p>\n Kamide, Y., Shue, J.-H., Hausman, B. A. & Freeman, J. W. Toward real-time mapping of ionospheric electric fields and currents. Adv. Space Res. 26, 213222 (2000).<\/p>\n Article ADS Google Scholar <\/p>\n Kamide, Y. Our life is protected by the Earths atmosphere and magnetic field: what aurora research tells us. Biomed. Pharmacother. 55, 2124 (2001).<\/p>\n Article Google Scholar <\/p>\n Kamide, Y. & Balan, N. The importance of ground magnetic data in specifying the state of magnetosphereionosphere coupling: a personal view. Geosci. Lett. 3, 10; https:\/\/doi.org\/10.1186\/s40562-016-0042-7<\/a> (2016).<\/p>\n Hughes, M.E. et al. Harmonics of circadian gene transcription in mammals. PLoS Genet. 5, e1000442; https:\/\/doi.org\/10.1371\/journal.pgen.1000442<\/a> (2009).<\/p>\n <\/p>\n See the rest here:<\/p>\n Unconscious mind activates central cardiovascular network and promotes adaptation to microgravity possibly anti-aging during 1-year-long spaceflight |...<\/a><\/p>\n","protected":false},"excerpt":{"rendered":" Zhang, L. Continue reading