Mallah, S. L. et al. COVID-19: Breaking down a global health crisis. Ann. Clin. Microbiol. Antimicrob. 20(1), 35 (2021).<\/p>\n
CAS PubMed PubMed Central Google Scholar <\/p>\n
Josephson, A., Kilic, T. & Michler, J. D. Socioeconomic impacts of COVID-19 in low-income countries. Nat. Hum. Behav. 5, 557565 (2021).<\/p>\n
PubMed Google Scholar <\/p>\n
De Pue, S. et al. The impact of the COVID-19 pandemic on wellbeing and cognitive functioning of older adults. Sci. Rep. 11, 4636 (2021).<\/p>\n
ADS PubMed PubMed Central Google Scholar <\/p>\n
Trabelsi, K. et al. Sleep quality and physical activity as predictors of mental wellbeing variance in older adults during COVID-19 lockdown: ECLB COVID-19 international online survey. Int. J. Environ. Res. Public Health 18(8), 4329. https:\/\/doi.org\/10.3390\/ijerph18084329<\/a> (2021).<\/p>\n Article PubMed PubMed Central Google Scholar <\/p>\n Mallapaty, S. et al. How COVID vaccines shaped 2021 in eight powerful charts. Nature 600, 580583 (2021).<\/p>\n ADS CAS PubMed Google Scholar <\/p>\n Sriram, K. et al. Beyond vaccines: Clinical status of prospective COVID-19 therapeutics. Front. Immunol. https:\/\/doi.org\/10.3389\/fimmu.2021.752227<\/a> (2021).<\/p>\n Article PubMed PubMed Central Google Scholar <\/p>\n Jensen, N., Kelly, A. H. & Avendano, M. The COVID-19 pandemic underscores the need for an equity-focused global health agenda. Hum. Soc. Sci. Commun. 8, 15. https:\/\/doi.org\/10.1057\/s41599-020-00700-x<\/a> (2021).<\/p>\n Article Google Scholar <\/p>\n Troeger, C., Blacker, B. F. & Khalil, I. A. Respiratory disease number 1 killer Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 19902016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet 18(11), P1191-1210 (2018).<\/p>\n Google Scholar <\/p>\n Edwards, D. A. et al. Hydration for clean air today. Mol. Front. J. https:\/\/doi.org\/10.1142\/S252973252101001X<\/a> (2021).<\/p>\n Article Google Scholar <\/p>\n Ghosh, A., Boucher, R. C. & Tarran, R. Airway hydration and COPD. Cell Mol. Life Sci. 72(19), 36373652 (2015).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Moriyama, M., Hugentobler, W. J. & Iwasaki, A. Seasonality of respiratory infections. Annu. Rev. Virol. 7(1), 8391 (2021).<\/p>\n Google Scholar <\/p>\n Lauc, G., Markoti, A., Gornik, I. & Primorac, D. Fighting COVID-19 with water. J. Glob. Health 10, 010344 (2020).<\/p>\n PubMed PubMed Central Google Scholar <\/p>\n Chumlea, W. C., Guo, S. S., Zeller, C. M., Reo, N. V. & Siervogel, R. M. Total body water data for white adults 18 to 64 years of age: The Fels Longitudinal Study. Kidney Int. 56, 244252 (1999).<\/p>\n CAS PubMed Google Scholar <\/p>\n Ritz, P. et al. Influence of gender and body composition on hydration and body water spaces. Clin. Nutr. 27, 740746 (2008).<\/p>\n CAS PubMed Google Scholar <\/p>\n Stookey, J. D., Allu, P. K. R., Chabas, D., Pearce, D. & Lang, F. Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19. Med. Hypotheses. 144, 110237 (2020).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Fronius, M., Clauss, W. G. & Althaus, M. Why do we have to move fluid to be able to breathe. Front. Physiol. 3, 146 (2012).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Hou, Y. J. et al. SARS-CoV2 reverse genetics reveals a variable infection gradient in the respiratory tract. Cell 182, 429446 (2020).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Zieliski, J. & Przybylski, J. How much water is lost during breathing?. Pneumonol. Alergol. Pol. 80(3), 339342 (2012).<\/p>\n PubMed Google Scholar <\/p>\n DAmato, M. et al. The impact of cold on the respiratory tract and its consequences to respiratory health. Clin. Transl. Allergy 8, 18 (2018).<\/p>\n Google Scholar <\/p>\n Kudo, E. et al. Low ambient humidity impairs barrier function and innate resistance against influenza infection. PNAS 116, 1090510910 (2019).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Barbet, J. P., Chauveau, M., Labbe, S. & Lockhart, A. Breathing dry air causes acute epithelial damage and inflammation of the guinea pig trachea. J. Appl. Physiol. 64, 18511857 (1988).<\/p>\n CAS PubMed Google Scholar <\/p>\n Wolkoff, P. The mystery of dry indoor air: An overview. Environ. Int. 121(2), 10581065 (2018).<\/p>\n PubMed Google Scholar <\/p>\n Romaszko-Wojtowicz, A. et al. Relationship between biometeorological factors and the number of hospitalizations due to asthma. Sci. Rep. 10, 9593 (2020).<\/p>\n ADS PubMed PubMed Central Google Scholar <\/p>\n Kudo, E. et al. Influenza worsens dry air Low ambient humidity impairs barrier function and innate resistance against influenza infection. Proc. Natl. Acad. Sci. USA 116(22), 1090510910 (2019).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Mecenas, P., Bastos, R., Vallinoto, A. & Normando, D. Effects of temperature and humidity on the spread of COVID-19: A systematic review. PLoS ONE 15(9), e0238339 (2020).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Rosen, C. & Simpson, C. Operative Techniques in Laryngology (Springer-Verlag, 2008).<\/p>\n Google Scholar <\/p>\n Finck, C. & Lejeune, L. Structure and oscillatory function of the vocal folds. In Handbook of Behavioral Neuroscience Vol. 19 (ed. Brudzynski, S. M.) 427438 (Elsevier, 2010).<\/p>\n Google Scholar <\/p>\n Zhuang, P. et al. Measurement of phonation threshold power in normal and disordered voice production. Ann. Otol. Rhinol. Laryngol. 122(9), 555560 (2013).<\/p>\n PubMed PubMed Central Google Scholar <\/p>\n Finklehor, B. K., Titze, I. R. & Durham, P. L. The effect of viscosity changes in the vocal folds on the range of oscillation. J. Voice 1, 320325 (1988).<\/p>\n Google Scholar <\/p>\n Sasaki, C. & Weaver, M. Physiology of the larynx. Am. J. Med. 103(5), 9S-18S (1997).<\/p>\n CAS PubMed Google Scholar <\/p>\n Scheinherr, A. Glottal Motion and Its Impact on Airflow and Aerosol Deposition in Upper Airways During Human Breathing. PhD Thesis, Fluids mechanics\/Physics. Ecole Centrale Marseille (2015).<\/p>\n Sivasankar, M. & Leyden, C. The role of hydration in vocal fold physiology. Curr. Opin. Otolaryngol. Head Neck Surg. 18(3), 171175 (2010).<\/p>\n PubMed PubMed Central Google Scholar <\/p>\n Van Hirtum, A., Bouvet, A. & Pelorson, X. Pressure drop for adiabatic air-water flow through a time-varying constriction. Phys Fluids 30, 101901 (2018).<\/p>\n ADS Google Scholar <\/p>\n Bouvet, A., Pelorson, X. & van Hirtum, A. Influence of water spraying on an oscillating channel. J. Fluids Struct. 93, 102840 (2020).<\/p>\n ADS Google Scholar <\/p>\n Xi, J., Longest, W. & Martonin, T. Effects of the laryngeal jet on nano- and microparticle transport and deposition in an approximate model of the upper tracheobronchial airways. J. Appl Phys. 104, 17611777 (2008).<\/p>\n Google Scholar <\/p>\n Xi, J., Si, A., Dong, H. & Zhong, H. Effects of glottis motion on airflow and energy expenditure in a human upper airway model. Eur. J. Mech. B 72, 2337 (2018).<\/p>\n ADS MathSciNet MATH Google Scholar <\/p>\n Peng, C.-A., Jurman, L. & McCready, M. Formation of solitary waves on gas-sheared liquid layers. Int. J. Multiph. Flow 17(6), 767782 (1991).<\/p>\n CAS MATH Google Scholar <\/p>\n Watanabe, W. & Why, W. inhaling salt water changes what we exhale. J. Colloid Interface Sci. 307(1), 7178 (2007).<\/p>\n ADS CAS PubMed Google Scholar <\/p>\n Stadnytskyi, V., Anfinruud, P. & Bax, A. Breathing, speaking, coughing or sneezing: What drives transmission of SARS-CoV-2?. J. Int. Med. 290, 10101027 (2021).<\/p>\n CAS Google Scholar <\/p>\n Scheuch, G. Breathing is enough: For the spread of influenza virus and SARS-CoV-2 by breathing only. J. Aerosol Med. Pulm. Drug Deliv. 33(4), 230234 (2020).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Field, R. et al. Moisture and airborne salt suppress respiratory droplet generation and may reduce COVID-19 incidence and death. Mol. Front. J. 5, 110 (2021).<\/p>\n Google Scholar <\/p>\n Calmet, H. et al. Nasal sprayed particle deposition in a human nasal cavity under different inhalation conditions. PLoS ONE 14(9), e0221330 (2019).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n Alves, M., Kruger, E., Pillay, B., van Lierde, K. & van der Linde, J. The effect of hydration on voice quality in adults: A systematic review. J. Voice 33, 1328 (2019).<\/p>\n Google Scholar <\/p>\n Edwards, D. A. et al. Inhaling to mitigate exhaled bioaerosols. Proc. Natl. Acad. Sci. USA 101(50), 1738317388 (2004).<\/p>\n ADS CAS PubMed PubMed Central Google Scholar <\/p>\n Hamed, R., Schenck, D. M. & Fiegel, J. Surface rheological properties alter aerosol formation from mucus mimetic surfaces. Soft Matter 16(33), 78237834 (2020).<\/p>\n ADS CAS PubMed Google Scholar <\/p>\n Crowther, R. S. & Marriott, C. Counter-ion binding to mucus glycoproteins. J. Pharm. Pharmacol. 36(1), 2126 (1984).<\/p>\n CAS PubMed Google Scholar <\/p>\n Edwards, D. A. et al. A new natural defense against airborne pathogens. QRB Discov. 1, e5 (2020).<\/p>\n PubMed PubMed Central Google Scholar <\/p>\n Edwards, D. A., Salzman, J., Devlin, T. & Langer, R. Nasal calcium-rich salts for cleaning airborne particles from the airways of essential workers, students, and a family in quarantine. Mol. Front. J. 4, 110 (2020).<\/p>\n CAS Google Scholar <\/p>\n George, C. E. et al. Airway hygiene in children and adults for lowering respiratory droplet exposure in health and learning environments in clean and dirty air. Mol. Front. J. 4, 4657 (2020).<\/p>\n CAS Google Scholar <\/p>\n Vishnoy, A. Insacog Data Too Confirm Rise of B.1.617 Across States. (India Economic Times, 2021). https:\/\/economictimes.indiatimes.com\/news\/india\/insacog-data-too-confirm-rise-of-b-1-617-across-states\/articleshow\/82781103.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst<\/a>.<\/p>\n Edwards, D. A. et al. Exhaled aerosol increases with COVID-19 infection, age, and obesity. PNAS 118, e2021830118 (2021).<\/p>\n CAS PubMed PubMed Central Google Scholar <\/p>\n <\/p>\n Read more: Mallah, S. L Continue reading
\nCOVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea | Scientific Reports - Nature.com<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"